Bp decline during 24 hours after stroke predicts outcomes
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Stroke patients' outcomes at 3 months worsen the further their blood pressure declines in the 24 hours after their attack, suggest findings from an analysis of NINDS tissue plasminogen activator stroke studies data. (Source: MedWire News - Stroke)
Source: MedWire News - Stroke - May 17, 2008 Category: Neurology Source Type: news
Improved cerebral vasoreactivity following percutaneous transluminal angioplasty with stenting of high-grade internal carotid artery stenosis
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Cerebrovasc Dis 2008;25:555-560 (DOI:10.1159/000132201) (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - May 17, 2008 Category: Neurology Source Type: journals
High satisfaction with an individualised stroke care programme after hospitalisation of patients with a tia or minor stroke: a pilot study
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Cerebrovasc Dis 2008;25:566-571 (DOI:10.1159/000132203) (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - May 17, 2008 Category: Neurology Source Type: journals
Stroke incidence in women under 60 years of age related to alcohol intake and smoking habit
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Cerebrovasc Dis 2008;25:517-525 (DOI:10.1159/000131669) (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - May 17, 2008 Category: Neurology Source Type: journals
Safety and efficacy of mri-based thrombolysis in unclear-onset stroke
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Cerebrovasc Dis 2008;25:572-579 (DOI:10.1159/000132204) (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - May 17, 2008 Category: Neurology Source Type: journals
Transient hyperperfusion after superficial temporal artery/middle cerebral artery bypass surgery as a possible cause of postoperative transient neurological deterioration
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Cerebrovasc Dis 2008;25:580-586 (DOI:10.1159/000132205) (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - May 17, 2008 Category: Neurology Source Type: journals
Executive functions and cognitive subprocesses in patients with obstructive sleep apnoea
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Journal of Sleep Research, Volume 0, Issue 0, Page ???, OnlineEarly Articles.
SummaryIn recent years, special interest has been focused on impairments of executive functions in patients with obstructive sleep apnoea syndrome (OSAS). However, the majority of studies have not clearly separated deficits in executive functions from ... (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - May 16, 2008 Category: Neurology Tags: article Source Type: journals
Anisotropy in the representation of direction preferences in cat area 18
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European Journal of Neuroscience, Volume 0, Issue 0, Page ???, December 2004.
AbstractHigher visual cortical areas are involved in the perception of complex stimuli, such as the optic flow created by self-motion. On the other hand, area 18 is thought to extract primitive visual features, feeding higher cortical areas for further ... (Source: European Journal of Neuroscience)
Source: European Journal of Neuroscience - May 16, 2008 Category: Neurology Tags: article Source Type: journals
Egr-1 is regulated by n-methyl-d-aspartate-receptor stimulation and associated with patient survival in human high grade astrocytomas
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Brain Pathology, Volume 0, Issue 0, Page ???, OnlineEarly Articles.
Abstract Early growth response-1 (EGR-1) is considered a central regulator in tumor cell proliferation, migration and angiogenesis and a promising candidate for gene therapy in human astrocytomas. However, conflicting data have been reported suggesting ... (Source: Brain Pathology)
Source: Brain Pathology - May 16, 2008 Category: Neurology Tags: article Source Type: journals
Multiple alpha-synuclein gene polymorphisms are associated with parkinson’s disease in a norwegian population
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Acta Neurologica Scandinavica, Volume 0, Issue 0, Page ???, December 2003.
Myhre R, Toft M, Kachergus J, Hulihan MM, Aasly JO, Klungland H, Farrer MJ. Multiple alpha-synuclein gene polymorphisms are associated with Parkinson’s disease in a Norwegian population.Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2008.01019.x© 2008 NTNU ... (Source: Acta Neurologica Scandinavica)
Source: Acta Neurologica Scandinavica - May 16, 2008 Category: Neurology Tags: article Source Type: journals
Alzheimer's and parkinson's diseases: progress and new perspectives. proceedings of the 8th international conference ad/pd, salzburg, austria, march 14-18, 2007.
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Alzheimer's and Parkinson's Diseases: Progress and New Perspectives. Proceedings of the 8th International Conference AD/PD, Salzburg, Austria, March 14-18, 2007.
Neurodegener Dis. 2008;5(3-4):109-266
Authors:
PMID: 18481370 [PubMed - indexed for MEDLINE] (Source: Neuro-Degenerative Diseases)
Source: Neuro-Degenerative Diseases - May 16, 2008 Category: Neurology Tags: Neurodegener Dis Source Type: journals
Beta blockers raise stroke risk in noncardiac surgery patients
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Giving beta blockers to patients undergoing noncardiac surgery reduces their risk for myocardial infarction but increases their risk for stroke and death, compared with placebo, results of POISE show. (Source: MedWire News - Stroke)
Source: MedWire News - Stroke - May 16, 2008 Category: Neurology Source Type: news
Profess: combination therapy falls short of noninferiority vs clopidogrel
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Results of a secondary stroke prevention trial show that the combination of aspirin and extended-release dipyridamole do not meet prespecified noninferiority criteria vs clopidogrel. Medscape Medical News (Source: Medscape Neurology & Neurosurgery Headlines)
Source: Medscape Neurology & Neurosurgery Headlines - May 16, 2008 Category: Neurology Tags: Neurology & Neurosurgery Source Type: info
Repeated administration of a dopamine d1 receptor agonist reverses the increased proportions of striatal dopamine d1high and d2high receptors in methamphetamine-sensitized rats
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European Journal of Neuroscience, Volume 0, Issue 0, Page ???, December 2004.
AbstractRepeated administration of psychostimulants produces a behavioural sensitization. Amphetamine-sensitized animals are known to have a higher proportion of high-affinity states of dopamine D2 receptors (D2High receptors) in the striatum. We recently ... (Source: European Journal of Neuroscience)
Source: European Journal of Neuroscience - May 16, 2008 Category: Neurology Tags: article Source Type: journals
Fine-tuning clot-busting treatment for bleeding in brain dramatically increases survival
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A multicenter study led by Johns Hopkins doctors has fine-tuned the dosage and timing for administering clot-busting tissue plasminogen activator (tPA) to patients with strokes caused by bleeding within the brain. The treatment, as reported this week at the European Stroke Conference in Nice, France, has been shown to dramatically decrease death and disability in patients with this typically lethal subset of stroke. (Source: Stroke / Neuroprotection News From Medical News Today)
Source: Stroke / Neuroprotection News From Medical News Today - May 16, 2008 Category: Neurology Source Type: news
23andme and the parkinson's institute announce initiative to advance parkinson's disease research
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23andMe, a privately-held personal genetics company, and The Parkinson's Institute and Clinical Center ("Parkinson's Institute") announced a research initiative under which Parkinson's Institute patients, with financial support from The Michael J. Fox Foundation, will enroll in the 23andMe Personal Genome Service™ to support the development of advanced methods for clinical and epidemiologic research for Parkinson's disease. (Source: Parkinson's Disease News From Medical News Today)
Source: Parkinson's Disease News From Medical News Today - May 16, 2008 Category: Neurology Source Type: news
Age 60 or older? get shingles vaccine
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Title: Age 60 or Older? Get Shingles VaccineCategory: Health NewsCreated: 5/16/2008Last Editorial Review: 5/16/2008 (Source: MedicineNet Migraine General)
Source: MedicineNet Migraine General - May 16, 2008 Category: Neurology Source Type: consumer
A comparison of parametric models for the investigation of the shape of cognitive change in the older population.
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Conclusions:
The combination of a latent growth model with a model for the missing data has permitted to make use of all available data and quantify the effect of significant predictors of dropout on the dropout and observational processes. Cognitive decline over time in older persons is often modelled as a linear process, though we have presented other parametric curves that may be considered. (Source: BMC Neurology)
Source: BMC Neurology - May 16, 2008 Category: Neurology Authors: Graciela Muniz, Fiona Matthews and Carol Brayne Source Type: journals
Leucine induces phosphorylation and activation of p70s6k in cortical neurons via the system l amino acid transporter
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Journal of Neurochemistry, Volume 0, Issue 0, Page ???, October 2004.
Abstractp70S6 kinase is a multipotent kinase that phosphorylates substrates in response to extracellular stimuli. This kinase activity inhibits apoptosis, regulates cell size and controls translation. In the CNS, p70S6K also participates in synaptic ... (Source: Journal of Neurochemistry)
Source: Journal of Neurochemistry - May 15, 2008 Category: Neurology Tags: article Source Type: journals
Utility, economic rationalism and the circumscription of agency
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Journal of Intellectual Disability Research, Volume 0, Issue 0, Page ???, December 2004.
Abstract Background Great strides have been achieved over the past few decades in service provision for people with intellectual disability (ID). However, there has also been a growth in the use of economic rationalism and a related rise in ... (Source: Journal of Intellectual Disability Research)
Source: Journal of Intellectual Disability Research - May 15, 2008 Category: Neurology Tags: article Source Type: journals
Post-stroke sexual functioning in first stroke patients
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European Journal of Neurology, Volume 0, Issue 0, Page ???, OnlineEarly Articles.
Background and purpose: Although physical problems after stroke have been well studied, there is little information on one of the crucial aspects of the quality of life of those patients, namely sexual functioning and satisfaction. The aim of this study ... (Source: European Journal of Neurology)
Source: European Journal of Neurology - May 15, 2008 Category: Neurology Tags: article Source Type: journals
Stroke risk identifies patients vulnerable to cognitive decline
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An individual's stroke risk is directly related to their cognitive function, researchers report. (Source: MedWire News - Stroke)
Source: MedWire News - Stroke - May 15, 2008 Category: Neurology Source Type: news
Combating stroke - outfitting device with drugs to prevent future stroke
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Dr. Pierre Gobin is the inventor of the MERCI Retriever, a catheter corkscrew device that slips into the blood vessels of the brain to hook onto and then remove blood clots. But now, Dr. Gobin is working on another pioneering advancement: the combination of the MERCI device with a drug delivery system to protect the affected part of the brain as blockages are removed. (Source: Stroke / Neuroprotection News From Medical News Today)
Source: Stroke / Neuroprotection News From Medical News Today - May 15, 2008 Category: Neurology Source Type: news
Profess(r) results announced at xvii european stroke conference
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Results of the PRoFESS(R) (Prevention Regimen For Effectively avoiding Second Strokes) trial -- the world's largest clinical research study for secondary stroke prevention -- were presented at the XVII European Stroke Conference in Nice, France. In the study, recurrent stroke event rates for Aggrenox(R) and clopidogrel were similar (9.0% and 8.8%, respectively; HR 1.01, 95% CI 0.92-1.11). (Source: Stroke / Neuroprotection News From Medical News Today)
Source: Stroke / Neuroprotection News From Medical News Today - May 15, 2008 Category: Neurology Source Type: news
Neurobiological technologies, inc. presents dosing rationale for viprinex(tm) (ancrod) at the european stroke conference
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Neurobiological Technologies, Inc. (NTI(R)) (Nasdaq: NTII) reported for the first time at the European Stroke Conference detailed analyses supporting the dosing regimen in NTI's two ongoing Phase 3 studies of Viprinex(TM) (ancrod) for ischemic stroke. (Source: Stroke / Neuroprotection News From Medical News Today)
Source: Stroke / Neuroprotection News From Medical News Today - May 15, 2008 Category: Neurology Source Type: news
Hypoxic preconditioning up-regulates glucose transport activity and glucose transporter (glut1 and glut3) gene expression after acute anoxic exposure in the cultured rat hippocampal neurons and astrocytes.
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In this study, the effects of hypoxic preconditioning on glucose transport activity and the gene expression of two major forms of glucose transporters (GLUT1 and GLUT3) in the brain were investigated in cultured rat hippocampal neurons and astrocytes. The neuronal and astroglial cultures were preconditioned for 6 days by intermittently exposing the cells to sublethal hypoxic gas mixture (1% O(2)/10% CO(2)/89% N(2)) for 20 min each day. 24 h after the last hypoxic exposure, the cells were exposed to a lethal anoxic gas mixture (10% CO(2)/90% N(2)) for 6 h and the uptake rate of [(3)H] 2-deoxyglucose (2-DG) and the levels of...
Source: Brain Research - May 15, 2008 Category: Neurology Authors: Yu S, Zhao T, Guo M, Fang H, Ma J, Ding A, Wang F, Chan P, Fan M Tags: Brain Res Source Type: journals
Study highlights need for early learning intervention in some children with ms
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Italian researchers compared cognitive function between 63 children with MS and 57 controls without MS, and found significant impairment in about one-third of the children with MS. The study results highlight the need for early interventions - such as accommodations that can be made in school - to address cognitive function in children with MS. Interventions of these types are among the comprehensive services offered at the National MS Society's network of Pediatric MS Centers of Excellence. (Source: Multiple Sclerosis News From Medical News Today)
Source: Multiple Sclerosis News From Medical News Today - May 15, 2008 Category: Neurology Source Type: news
Pharmacists play important part in stroke services
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The English Pharmacy Board of the Royal Pharmaceutical Society of Great Britain welcomes the government's emphasis on stroke treatment, as outlined in the recent announcement by the Department of Health to boost funding for stroke services. The number of patients receiving anticoagulation therapy has increased over the last years. (Source: Stroke / Neuroprotection News From Medical News Today)
Source: Stroke / Neuroprotection News From Medical News Today - May 15, 2008 Category: Neurology Source Type: news
Developmental and comparative aspects of posterior medial thalamocortical innervation of the barrel cortex in mice and rats
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The thalamocortical projection to the rodent barrel cortex consists of inputs from the ventral posterior medial (VPM) and posterior medial (POm) nuclei that terminate in largely non-overlapping territories in and outside of layer IV. This projection in both rats and mice has been used extensively to study development and plasticity of highly organized synaptic circuits. Whereas the VPM pathway has been well characterized in both rats and mice, organization of the POm pathway has only been described in rats, and no studies have focused exclusively on the development of the POm projection. Here, using transport of Phaseolus ...
Source: The Journal of Comparative Neurology - May 15, 2008 Category: Neurology Authors: Elizabeth A. Kichula, George W. Huntley Tags: Articles Source Type: journals
Tranilast ameliorates experimental mesangial proliferative glomerulonephritis
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Nephron Exp Nephrol 2008;109:e1 (DOI:10.1159/000131752) (Source: Nephron Experimental Nephrology)
Source: Nephron Experimental Nephrology - May 15, 2008 Category: Neurology Source Type: journals
Dexamethasone's prosurvival benefits in podocytes require extracellular signal-regulated kinase phosphorylation
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Nephron Exp Nephrol 2008;109:e8 (DOI:10.1159/000131892) (Source: Nephron Experimental Nephrology)
Source: Nephron Experimental Nephrology - May 15, 2008 Category: Neurology Source Type: journals
Levodopa-induced dyskinesias in parkinson's disease: etiology, impact on quality of life, and treatments
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Eur Neurol 2008;60:57-66 (DOI:10.1159/000131893) (Source: European Neurology)
Source: European Neurology - May 15, 2008 Category: Neurology Source Type: journals
Pure eye muscle involvement in endocrine orbitopathy
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Eur Neurol 2008;60:67-72 (DOI:10.1159/000131894) (Source: European Neurology)
Source: European Neurology - May 15, 2008 Category: Neurology Source Type: journals
Clock-drawing test performance in the normal elderly and its dependence on age and education
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Eur Neurol 2008;60:73-78 (DOI:10.1159/000131895) (Source: European Neurology)
Source: European Neurology - May 15, 2008 Category: Neurology Source Type: journals
Mri-based score for acute basilar artery thrombosis
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Cerebrovasc Dis 2008;25:511-516 (DOI:10.1159/000131668) (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - May 15, 2008 Category: Neurology Source Type: journals
Association between metabolic syndrome and risk of stroke: a meta-analysis of cohort studies
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Cerebrovasc Dis 2008;25:539-547 (DOI:10.1159/000131672) (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - May 15, 2008 Category: Neurology Source Type: journals
The impact of stroke on unpaid caregivers: results from the auckland regional community stroke study, 2002--2003
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Cerebrovasc Dis 2008;25:548-554 (DOI:10.1159/000131673) (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - May 15, 2008 Category: Neurology Source Type: journals
Long-term stroke prognosis in relation to medical prevention and lifestyle factors
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Cerebrovasc Dis 2008;25:526-532 (DOI:10.1159/000131670) (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - May 15, 2008 Category: Neurology Source Type: journals
Clinical severity predicts time to hospital admission in patients with spontaneous intracerebral hemorrhage
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Cerebrovasc Dis 2008;25:533-538 (DOI:10.1159/000131671) (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - May 15, 2008 Category: Neurology Source Type: journals
Myelin-induced microglial neurotoxicity can be controlled by microglial metabotropic glutamate receptors
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Journal of Neurochemistry, Volume 0, Issue 0, Page ???, October 2004.
AbstractMicroglia are present in an activated state in multiple sclerosis lesions. Incubation of primary cultured rat microglia with rat-brain derived myelin (0.1–1 μg/mL) for 24 h induced microglial activation; cells displayed enhanced ED1 staining, ... (Source: Journal of Neurochemistry)
Source: Journal of Neurochemistry - May 15, 2008 Category: Neurology Tags: article Source Type: journals
Cycloserine-induced encephalopathy: evidence on brain mri
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European Journal of Neurology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. (Source: European Journal of Neurology)
Source: European Journal of Neurology - May 15, 2008 Category: Neurology Tags: article Source Type: journals
Hexosaminidase a deficiency as a differential of amyotrophic lateral sclerosis
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European Journal of Neurology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. (Source: European Journal of Neurology)
Source: European Journal of Neurology - May 15, 2008 Category: Neurology Tags: article Source Type: journals
Frontotemporal dementia linked to chromosome 3 (ftd-3) – current concepts and the detection of a previously unknown branch of the danish ftd-3 family
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European Journal of Neurology, Volume 0, Issue 0, Page ???, OnlineEarly Articles.
Background: Among patients with onset of dementia below the age of 65 years, frontotemporal dementia (FTD) is the second most prevalent cause, secondary only to Alzheimer’s disease. Recent advances in understanding the heterogeneous genetic background for ... (Source: European Journal of Neurology)
Source: European Journal of Neurology - May 15, 2008 Category: Neurology Tags: article Source Type: journals
Cardiovagal modulation upon postural change is altered in huntington’s disease
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Conclusions: The pattern of linear heart rate variability we found in mid ... (Source: European Journal of Neurology)
Source: European Journal of Neurology - May 15, 2008 Category: Neurology Tags: article Source Type: journals
Monitoring of cbfv and time characteristics of oxygen-induced acute cns toxicity in humans
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European Journal of Neurology, Volume 0, Issue 0, Page ???, OnlineEarly Articles.
Background: Hyperbaric oxygen can cause central nervous system (CNS) toxicity with seizures. We tested the hypothesis that CNS toxicity could be predictable by cerebral blood flow velocity (CBFV) monitoring.Method: We monitored 369 mandatory oxygen ... (Source: European Journal of Neurology)
Source: European Journal of Neurology - May 15, 2008 Category: Neurology Tags: article Source Type: journals
The ipsilateral cortico-spinal tract is activated after hemiparetic stroke
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European Journal of Neurology, Volume 0, Issue 0, Page ???, OnlineEarly Articles.
Background and purpose: The presence of a projection from the primary motor cortex to the ipsilateral muscles has been established in human, but whether this pathway contributes to functional recovery after stroke is unclear. We investigated whether the ... (Source: European Journal of Neurology)
Source: European Journal of Neurology - May 15, 2008 Category: Neurology Tags: article Source Type: journals
Pedunculopontine nucleus stimulation influences rem sleep in parkinson’s disease
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European Journal of Neurology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. (Source: European Journal of Neurology)
Source: European Journal of Neurology - May 15, 2008 Category: Neurology Tags: article Source Type: journals
Drd3 ser9gly variant is not associated with essential tremor in a series of italian patients
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European Journal of Neurology, Volume 0, Issue 0, Page ???, OnlineEarly Articles.
Background: Essential tremor (ET) is the most common movement disorder worldwide. Three susceptibility loci on chromosomes 3q13, 2p24.1, and 6p23 have been reported, but no causative genes were found. The Ser9Gly variant of dopamine D3 receptor (DRD3) ... (Source: European Journal of Neurology)
Source: European Journal of Neurology - May 15, 2008 Category: Neurology Tags: article Source Type: journals
Do tias require investigation by thin-slice high-resolution diffusion mri with a 3t mr unit?
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European Journal of Neurology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. (Source: European Journal of Neurology)
Source: European Journal of Neurology - May 15, 2008 Category: Neurology Tags: article Source Type: journals
The prevalence of the g2019s and r1441c/g/h mutations in lrrk2 in german patients with parkinson’s disease
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European Journal of Neurology, Volume 0, Issue 0, Page ???, OnlineEarly Articles.
Background and purpose: The prevalence of the heterozygous G2019S and R1441C/G/H mutations in LRRK2 in patients with Parkinson’s disease (PD) has shown a great variability depending on the sample population. Here we investigated the prevalence of these ... (Source: European Journal of Neurology)
Source: European Journal of Neurology - May 15, 2008 Category: Neurology Tags: article Source Type: journals
