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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 22.

Child development: agreement between the child health handbook and the guide for monitoring child development
CONCLUSIONS: The agreement between both tools was poor.OBJETIVO: Verificar la concordancia entre los instrumentos Libreta de Salud del Niño (CSC, sigla en portugués) y Manual para Vigilancia del Desarrollo Infantil en el Contexto de la Atención Integrada a las Enfermedades Prevalentes en la Infancia (AIDPI, sigla en portugués) en la evaluación del desarrollo infantil en niños de dos a 24 meses de edad. MÉTODOS: Estudio transversal realizado en una Unidad Básica de Salud (UBS) de Belo Horizonte (Minas Gerais, Brasil), entre marzo de 2009 y marzo de 2010. Después de inventariar el número de niños adscritos a la UB...
Source: Revista Paulista de Pediatria - January 8, 2013 Category: Pediatrics Source Type: research

Importance of neurodevelopment monitoring in preterm newborn infants
Source: Revista Paulista de Pediatria - January 8, 2013 Category: Pediatrics Source Type: research

Temporal resolution in sensorineural hearing loss and brain injury
Com o objetivo de compreender as relações entre o gesto e a linguagem e a relevância do gesto no desenvolvimento de competências comunicativo-linguísticas foi realizada uma pesquisa da literatura nacional e internacional. A análise dos dados de múltiplas áreas científicas indica influências transversais do gesto natural na evolução da competência comunicativo-linguística do Homem. Assim, a identificação do sistema de neurónios-espelho promoveu o emergir de vários trabalhos que levantaram hipóteses sobre o paralelismo entre a evolução do gesto versus a evolução da linguagem. A literatura aponta que os...
Source: Revista da Sociedade Brasileira de Fonoaudiologia - January 8, 2013 Category: Audiology Source Type: research

Food in liquid consistency and deglutition: a critical review of the literature
O objetivo da presente revisão de literatura foi analisar artigos científicos internacionais publicados sobre a fisiologia da deglutição de alimentos líquidos nas fases oral e faríngea. A metodologia empregada envolveu a formulação da pergunta; localização e seleção dos estudos; avaliação crítica dos artigos; conforme os preceitos do Cochrane Handbook. Foram identificados 185 artigos, dos quais se excluiu 141 por não relacionarem-se diretamente ao tema e analisou-se 29 estudos. As pesquisas estão fortemente relacionadas às formas de identificação de disfagia e não as características proporcionadas pel...
Source: Revista da Sociedade Brasileira de Fonoaudiologia - January 8, 2013 Category: Audiology Source Type: research

Reducing Serum Uric Acid Attenuates TGF-β1-Induced Profibrogenic Progression in Type 2 Diabetic Nephropathy
Nephron Exp Nephrol 2012;121:e108–e120 (DOI:10.1159/000343567)
Source: Nephron Experimental Nephrology - January 8, 2013 Category: Neurology Source Type: research

Influences of Personality Traits on Quality of Life after Stroke
Eur Neurol 2013;69:185–192 (DOI:10.1159/000345699)
Source: European Neurology - January 8, 2013 Category: Neurology Source Type: research

Dexter Talks Psychopath Stress Management
Michael C. Hall: “I think what is most remarkable about Dexter is his capacity for stress management.” [More]
Source: Scientific American - Official RSS Feed - January 8, 2013 Category: Science Tags: Mind & Brain,Psychiatry,Psychology,Mind Source Type: research

Causes and Trends in Traumatic Brain Injury for United States Adolescents
Journal of Neurotrauma Jan 2013, Vol. 30, No. 2: 67-75.
Source: Journal of Neurotrauma - January 8, 2013 Category: Neurology Tags: article Source Type: research

Medial Septal Nucleus Theta Frequency Deep Brain Stimulation Improves Spatial Working Memory after Traumatic Brain Injury
Journal of Neurotrauma Jan 2013, Vol. 30, No. 2: 131-139.
Source: Journal of Neurotrauma - January 8, 2013 Category: Neurology Tags: article Source Type: research

A Multiscale Computational Approach to Estimating Axonal Damage under Inertial Loading of the Head
Journal of Neurotrauma Jan 2013, Vol. 30, No. 2: 102-118.
Source: Journal of Neurotrauma - January 8, 2013 Category: Neurology Tags: article Source Type: research

Remote Epidural Hemorrhage after Unilateral Decompressive Hemicraniectomy in Brain-Injured Patients
Journal of Neurotrauma Jan 2013, Vol. 30, No. 2: 96-101.
Source: Journal of Neurotrauma - January 8, 2013 Category: Neurology Tags: article Source Type: research

Trends in Outcomes and Hospitalization Costs for Traumatic Brain Injury in Adult Patients in the United States
Journal of Neurotrauma Jan 2013, Vol. 30, No. 2: 84-90.
Source: Journal of Neurotrauma - January 8, 2013 Category: Neurology Tags: article Source Type: research

Bone Flap Resorption: Risk Factors for the Development of a Long-Term Complication following Cranioplasty after Decompressive Craniectomy
Journal of Neurotrauma Jan 2013, Vol. 30, No. 2: 91-95.
Source: Journal of Neurotrauma - January 8, 2013 Category: Neurology Tags: article Source Type: research

Cognitive Recovery and Development after Traumatic Brain Injury in Childhood: A Person-Oriented, Longitudinal Study
Journal of Neurotrauma Jan 2013, Vol. 30, No. 2: 76-83.
Source: Journal of Neurotrauma - January 8, 2013 Category: Neurology Tags: article Source Type: research

A Clinical Trial and Suicide Leave Many Questions: Part 4: The University of Minnesota's Response
[caption id="attachment_4186" align="alignleft" width="300" caption="Bowl of antidepressants"] [/caption]In earlier posts, we've looked at issues of consen t, investigator responsibilities , and conflicts of interest on the case of Dan Markingson's suicide while participating in a clinical trial of anti-psychotics at the University of Minnesota. This time, we turn to the University's response. [More]
Source: Scientific American - Official RSS Feed - January 8, 2013 Category: Science Tags: Health,Mind & Brain Source Type: research

Investigation of the Human Brain Metabolome to Identify Potential Markers for Early Diagnosis and Therapeutic Targets of Alzheimer’s Disease
Analytical ChemistryDOI: 10.1021/ac303163f
Source: Analytical Chemistry - January 8, 2013 Category: Chemistry Authors: Stewart F. Graham, Olivier P. Chevallier, Dominic Roberts, Christian Hölscher, Christopher T. Elliott and Brian D. Green Source Type: research

Psychologists Uncover Hidden Signals of Trust Using a Robot
“In spite of the hardness and ruthlessness I thought I saw in his face, I got the impression that here was a man who could be relied upon when he had given his word." [More]
Source: Scientific American - Official RSS Feed - January 8, 2013 Category: Science Tags: Mind & Brain,Psychology,Mind Source Type: research

Comparison of fetal heart rate patterns using nonlinear dynamics in breech versus cephalic presentation at term
Conclusion: Our data suggest that breech fetuses have neither more active ANS nor less active complexity control systems than do cephalic fetuses. This indicates that the neurologic maturation of breech fetuses is not inferior to cephalic ones. The practical implication of these findings is that the nervous system integrity of breech fetuses may not result directly in neonatal complications.
Source: Early Human Development - January 8, 2013 Category: Perinatology & Neonatology Authors: Young-Sun Park, Ki-Young Ryu, Soon-Sup Shim, Jeong-Kyu Hoh, Moon-Il Park Source Type: research

Early detection of minor neurodevelopmental dysfunctions at age 6months in prematurely born neonates
Conclusions: Premature neonates, even those born at 33 to 36weeks, are found to have MNDs as early as 6months corrected age by BSID-II and DDST, with risk increasing as gestation decreases.
Source: Early Human Development - January 8, 2013 Category: Perinatology & Neonatology Authors: Jen-Fu Hsu, Ming-Horng Tsai, Shih-Ming Chu, Ren-Huei Fu, Ming-Chou Chiang, Fan-Ming Hwang, Miao-Ju Kuan, Yu-Shu Huang Source Type: research

Neurobehavioral assessment of infants born at term and in utero exposure to serotonin reuptake inhibitors
Conclusion: Results of this study show differences in autonomic and gross motor activity between neonates who were or were not exposed to SRIs in utero after controlling for active maternal psychiatric illness. Future longitudinal work should compare longer term outcomes of exposed and unexposed infants of depressed mothers.
Source: Early Human Development - January 8, 2013 Category: Perinatology & Neonatology Authors: Megan V. Smith, Anita Sung, Bhavesh Shah, Linda Mayes, Deborah S. Klein, Kimberly A. Yonkers Source Type: research

Development of clinical signs in low risk term born infants with neonatal hyperexcitability
Conclusion: Our data suggest that neonatal tremors can have a variable evolution and rate of resolution, with 70% of recovery by 9months with a normal outcome at 24months in all. The risk of persistence of signs (at 12months) in infants with either isolated tremors or increased resistance to passive movements is lower than in the subgroup with both signs at one month.
Source: Early Human Development - January 8, 2013 Category: Perinatology & Neonatology Authors: Daniela Leone, Claudia Brogna, Daniela Ricci, Domenico M. Romeo, Giuseppina Leo, Francesca Serrao, Francesca Gallini, Giovanni Cioni, Costantino Romagnoli, Eugenio Mercuri Source Type: research

Asymmetry in neural fields: a spatiotemporal encoding mechanism.
Abstract Neural field models have been successfully applied to model diverse brain mechanisms like visual attention, motor control, and memory. Most theoretical and modeling works have focused on the study of the dynamics of such systems under variations in neural connectivity, mainly symmetric connectivity among neurons. However, less attention has been given to the emerging properties of neuron populations when neural connectivity is asymmetric, although asymmetric activity propagation has been observed in cortical tissue. Here we explore the dynamics of neural fields with asymmetric connectivity and show, in the...
Source: Biological Cybernetics - January 8, 2013 Category: Science Authors: Cerda M, Girau B Tags: Biol Cybern Source Type: research

Molecular characterization of a mosaic NIPBL deletion in a Cornelia de Lange patient with severe phenotype.
We describe a CdLS patient with classic severe phenotype who was found negative to mutations in the NIPBL and SMC1A genes by DHPLC and direct sequencing. MLPA analysis performed to disclose potential intragenic NIPBL deletions/duplications, suggested a partial deletion which was confirmed by FISH with a BAC clone encompassing the NIPBL region that highlighted asymmetric signals in a fraction of cells (72%). The occurrence of a genomic deletion in mosaic condition was validated by array-CGH analysis. Long-range PCR and sequencing of the junction fragment mapped the telomeric and the centromeric breakpoint within NIPBL IVS1 ...
Source: European Journal of Medical Genetics - January 8, 2013 Category: Genetics & Stem Cells Authors: Gervasini C, Parenti I, Picinelli C, Azzollini J, Masciadri M, Cereda A, Selicorni A, Russo S, Finelli P, Larizza L Tags: Eur J Med Genet Source Type: research

The Adult Netherlands Twin Register: Twenty-Five Years of Survey and Biological Data Collection.
This article provides an overview of the sources of information available, the main research findings, and an outlook for the future. Between 1991 and 2012, longitudinal surveys were completed by twins, their parents, siblings, spouses, and offspring. Data are available for 33,957 participants, with most individuals having completed two or more surveys. Smaller projects provided in-depth phenotyping, including measurements of the autonomic nervous system, neurocognitive function, and brain imaging. For 46% of the ANTR participants, DNA samples are available and whole genome scans have been obtained in more than 11,000 indi...
Source: Twin Research and Human Genetics - January 8, 2013 Category: Genetics & Stem Cells Authors: Willemsen G, Vink JM, Abdellaoui A, den Braber A, van Beek JH, Draisma HH, van Dongen J, van 't Ent D, Geels LM, van Lien R, Ligthart L, Kattenberg M, Mbarek H, de Moor MH, Neijts M, Pool R, Stroo N, Kluft C, Suchiman HE, Slagboom PE, de Geus EJ, Boomsma Tags: Twin Res Hum Genet Source Type: research

An Overview of Multidisciplinary Research Resources at the Osaka University Center for Twin Research.
Abstract Osaka University Center for Twin Research is currently organizing a government-funded, multidisciplinary research project using a large registry of aged twins living in Japan. The purpose of the project is to collect various information as well as biological resources from registered twins, and to establish a biobank and databases for preserving and managing these data and resources. The Center is collecting data from twin pairs, both of whom have agreed to participate in a one-day comprehensive medical examination. The following data are being collected: physical data (e.g., height, body mass, blood press...
Source: Twin Research and Human Genetics - January 8, 2013 Category: Genetics & Stem Cells Authors: Hayakawa K, Iwatani Y, the Osaka Twin Research Group Tags: Twin Res Hum Genet Source Type: research

Hereditary hemorrhagic telangiectasia, liver vascular malformations and cardiac consequences.
CONCLUSION: Performing echocardiography in HHT patients with dyspnea allowed us to better understand the physiological processes of high-CO failure complicating liver vascular malformations and may improve follow-up of patients and treatment decisions. PMID: 23312966 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - January 8, 2013 Category: Internal Medicine Authors: Ginon I, Decullier E, Finet G, Cordier JF, Marion D, Saurin JC, Dupuis-Girod S Tags: Eur J Intern Med Source Type: research

Prognostic Value of Preoperative Border-zone (Watershed) Infarcts on the Early Postoperative Outcomes of Carotid Endarterectomy after Acute Ischemic Stroke.
CONCLUSION: CBZIs, compared to TCIS, were associated with a higher neurological complication rate during the postoperative period after CEA for SCS in cases of AIS. Further studies are required to better define the timing and the best treatment modality for patients with CBZI related to an SCS in order to reduce associated procedural complications. PMID: 23312506 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - January 8, 2013 Category: Surgery Authors: Jean-Baptiste E, Perini P, Suissa L, Lachaud S, Declemy S, Mahagne MH, Mousnier A, Hassen-Khodja R Tags: Eur J Vasc Endovasc Surg Source Type: research

Safe surgical technique: cement-augmented pedicle screw instrumentation and balloon-guided kyphoplasty for a lumbar burst fracture in a 97-year-old patient.
CONCLUSION: Especially in older patients, the presented technique of PMMA-augmented pedicle screw instrumentation combined with balloon-assisted kyphoplasty could be an option to address unstable vertebral fractures in "a minor-invasive way". The standard procedure of a two-step dorsoventral approach could be reduced to a one-step procedure. PMID: 23298619 [PubMed - as supplied by publisher]
Source: Patient Safety in Surgery - January 8, 2013 Category: Surgery Authors: Freude T, König B, Martetschläger F, Siebenlist S, Neumaier M, Stöckle U, Döbele S Tags: Patient Saf Surg Source Type: research

Hypersexual Behavior in Frontotemporal Dementia: A Comparison with Early-Onset Alzheimer's Disease.
This study reviewed 47 patients with bvFTD compared to 58 patients with Alzheimer's disease (AD) for the presence of heightened sexual activity to the point of distress to caregivers and others. Hypersexual behavior occurred in 6 (13 %) bvFTD patients compared to none of the AD patients. Caregivers judged all six bvFTD patients with hypersexual behavior as having a dramatic increase in sexual frequency from premorbid levels. All had general disinhibition, poor impulse control, and actively sought sexual stimulation. They had widened sexual interests and experienced sexual arousal from previously unexciting stimuli. One pa...
Source: Archives of Sexual Behavior - January 8, 2013 Category: Psychiatry & Psychology Authors: Mendez MF, Shapira JS Tags: Arch Sex Behav Source Type: research

Axonopathy in an α-Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal-Truncated α-Synuclein.
Abstract Progressive accumulation of α-synuclein (α-syn) in limbic and striatonigral systems is associated with the neurodegenerative processes in dementia with Lewy bodies (DLB) and Parkinson's disease (PD). The murine Thy-1 (mThy1)-α-syn transgenic (tg) model recapitulates aspects of degenerative processes associated with α-syn accumulation in these disorders. Given that axonal and synaptic pathologies are important features of DLB and PD, we sought to investigate the extent and characteristics of these alterations in mThy1-α-syn tg mice and to determine the contribution of α-syn c-terminally cleaved at ami...
Source: The American Journal of Pathology - January 8, 2013 Category: Pathology Authors: Games D, Seubert P, Rockenstein E, Patrick C, Trejo M, Ubhi K, Ettle B, Ghassemiam M, Barbour R, Schenk D, Nuber S, Masliah E Tags: Am J Pathol Source Type: research

Animal model of Mycoplasma fermentans respiratory infection
Conclusions: Mycoplasma fermentans induced a respiratory tract infection and persisted in different organs for several weeks in hamsters. This finding may help to explain the ability of Mycoplasma fermentans to induce pneumonia and chronic infectious diseases in humans.
Source: BMC Research Notes - January 8, 2013 Category: Research Authors: Antonio YáñezAzucena Martínez-RamosTeresa CalixtoFrancisco González-MatusJosé Rivera-TapiaSilvia GionoConstantino GilLilia Cedillo Source Type: research

Pachymeningeal Enhancement on MRI: A Venous Phenomena Not Always Related to Intracranial Hypotension (Resolving Pachymeningeal Enhancement and Cerebral Vein Thrombosis).
PMID: 23298153 [PubMed - as supplied by publisher]
Source: Headache - January 8, 2013 Category: Neurology Authors: Rozen TD Tags: Headache Source Type: research

Unique Case of "Post-Lumbar Puncture Headache"
We report a unique case of a spontaneous frontal epidural hematoma following a therapeutic lumbar puncture in a patient with a history of idiopathic intracranial hypertension. This case highlights the importance of symptomatology in patients following LPs by revealing a rare intracranial presentation that would be devastating if not discovered promptly and appropriately managed. PMID: 23298181 [PubMed - as supplied by publisher]
Source: Headache - January 8, 2013 Category: Neurology Authors: Patel BA, Williams NR, Pritchard PB Tags: Headache Source Type: research

Visual Evoked Potentials in Interictal Migraine: No Confirmation of Abnormal Habituation.
CONCLUSION.-: Reversal rate and check-size differences do not seem to explain the discrepant visual evoked potential habituation results in the migraine literature. Furthermore, no differences in first block amplitudes or N70, P100, and N145 latencies between healthy controls and migraineurs were found. We recommend blinded evaluation designs in future habituation studies in migraine. PMID: 23298223 [PubMed - as supplied by publisher]
Source: Headache - January 8, 2013 Category: Neurology Authors: Omland PM, Nilsen KB, Uglem M, Gravdahl G, Linde M, Hagen K, Sand T Tags: Headache Source Type: research

Ketorolac in the Treatment of Acute Migraine: A Systematic Review.
Abstract This systematic review examined the effectiveness of parenteral ketorolac (KET) in acute migraine. Acute migraine headaches are common emergency department presentations, and despite evidence for various treatments, there is conflicting evidence regarding the use of KET. Searches of MEDLINE, EMBASE, Cochrane, CINAHL, and gray literature sources were conducted. Included studies were randomized controlled trials in which KET alone or in combination with abortive therapy was compared with placebo or other standard therapy in adult patients with acute migraine. Two reviewers assessed relevance, inclusion, and ...
Source: Headache - January 8, 2013 Category: Neurology Authors: Taggart E, Doran S, Kokotillo A, Campbell S, Villa-Roel C, Rowe BH Tags: Headache Source Type: research

[EEG - when and how?].
This article is based on articles from personal literature archives and literature searches in PubMed, textbook on methods in clinical neurophysiology, the work of one of the authors on a new European standard for EEG and the authors' clinical experience.RESULTS EEG is primarily indicated for assessing suspected epileptic seizures and encephalopathies. Standard EEG, sleep-deprived EEG and long-term EEG examinations are used in diagnosing epilepsy. EEG will identify epileptiform activity in about 90 % of patients with epilepsy. Epileptiform EEG activity in these patients will provide support for the diagnosis of epilepsy, ...
Source: Tidsskrift for den Norske Laegeforening - January 8, 2013 Category: Journals (General) Authors: Herigstad A, Stefansdottir S, Aurlien H Tags: Tidsskr Nor Laegeforen Source Type: research

EEG in connection with coma.
Abstract BACKGROUND Coma is a dynamic condition that may have various causes. Important changes may take place rapidly, often with consequences for treatment. The purpose of this article is to provide a brief overview of EEG patterns in comas with various causes, and indicate how EEG contributes in an assessment of the prognosis for coma patients.METHOD The article is based on many years of clinical and research-based experience of EEG used for patients in coma. A self-built reference database was supplemented by searches for relevant articles in PubMed.RESULTS EEG reveals immediate changes in coma, and can provide...
Source: Tidsskrift for den Norske Laegeforening - January 8, 2013 Category: Journals (General) Authors: Wilson JA, Nordal HJ Tags: Tidsskr Nor Laegeforen Source Type: research

[Polysomnography (PSG) for studying sleep disorders].
Abstract BACKGROUND. Sleeping problems are very common, and many patients need a comprehensive assessment with polysomnography, possibly followed by a sleep latency test. These methods and indications for the tests are described below.METHOD. The article is based on the authors' own literature archives, clinical experience and Retningslinjer for metoder i klinisk neurofysiologi [Guidelines for methodology in clinical neurophysiology]RESULTS. Polysomnography involves monitoring sleep through the course of one night and scoring the stages of sleep on the basis of EEG activity, eye movements and muscular tension. Also...
Source: Tidsskrift for den Norske Laegeforening - January 8, 2013 Category: Journals (General) Authors: Engstrøm M, Rugland E, Skard Heier M Tags: Tidsskr Nor Laegeforen Source Type: research

[A case of glucose-sensitive insulinoma accompanied by slightly elevated serum insulin levels and persisting convulsions after the surgically removed neuroendocrine tumor].
Abstract Insul(in)oma is a usually solitary or, in some cases, multifocal tumor of pancreatic beta cells. It may be a component of multiple endocrine neoplasia type 1. or von Hippel-Lindau syndrome. In typical forms the diagnosis - based on the Whipple triad - is simple, however, it may be difficult to recognize in cases with near normal or only slightly elevated serum insulin levels, as well as in patients with known convulsive episodes. With the case presentation of an 81-year-old woman the authors draw attention to the pitfalls of the correct diagnosis. A special feature of the presented case is that convulsions...
Source: Orvosi Hetilap - January 8, 2013 Category: Journals (General) Authors: Soós Z, Czégeni A, Salamon F, Salamon M, Kenessey I, Folyovich A, Tihanyi T, Winkler G Tags: Orv Hetil Source Type: research

Attentional functioning in patients with posttraumatic stress disorder: a preliminary study.
Conclusion PTSD patients were impaired relative to participants without psychiatric diagnoses on a measure of focused attention. Several factors, including the small sample size, suggest that the results should be considered preliminary. PMID: 23298713 [PubMed - as supplied by publisher]
Source: CNS Spectrums - January 8, 2013 Category: Neurology Authors: Horner MD, Mintzer JE, Turner TH, Edmiston KR, Brawman-Mintzer O Tags: CNS Spectr Source Type: research

Correlation of microrna-372 upregulation with poor prognosis in human glioma
MicroRNA-372 (miR-372) acts as either an oncogenic miRNA or an anti-oncomiR in varioushuman malignancies. However, its roles in gliomas have not been elucidated. To address thisproblem, we here detected miR-372 expression in human gliomas and non-neoplastic braintissues by real-time quantitative RT-PCR assay. The association of miR-372 expression withclinicopathological factors or prognosis of glioma patients was also statistically analyzed. Asthe results, miR-372 expression levels were significantly upregulated in glioma tissuescompared to the corresponding non-neoplastic brain tissues (P
Source: Diagnostic Pathology - January 8, 2013 Category: Pathology Authors: Gang LiZhiguo ZhangYanyang TuTianbo JinHongjuan LiangGuangbin CuiShiming HeGuodong Gao Source Type: research

The short- and long-term risk of venous thromboembolism in patients with acute spinal cord injury. A prospective cohort study.
In conclusion, the risk of VTE in patients suffering from SCI is high despite the use of thromboprophylaxis, in particular in some patients categories. However, this risk appears to be limited to the first 3 months after the index event. PMID: 23223906 [PubMed - in process]
Source: Thrombosis and Haemostasis - January 8, 2013 Category: Hematology Authors: Giorgi Pierfranceschi M, Donadini MP, Dentali F, Ageno W, Marazzi M, Bocchi R, Imberti D Tags: Thromb Haemost Source Type: research

Correlation of microrna-372 upregulation with poor prognosis in human glioma
MicroRNA-372 (miR-372) acts as either an oncogenic miRNA or an anti-oncomiR in varioushuman malignancies. However, its roles in gliomas have not been elucidated. To address thisproblem, we here detected miR-372 expression in human gliomas and non-neoplastic braintissues by real-time quantitative RT-PCR assay. The association of miR-372 expression withclinicopathological factors or prognosis of glioma patients was also statistically analyzed. Asthe results, miR-372 expression levels were significantly upregulated in glioma tissuescompared to the corresponding non-neoplastic brain tissues (P
Source: Diagnostic Pathology - January 8, 2013 Category: Pathology Authors: Gang LiZhiguo ZhangYanyang TuTianbo JinHongjuan LiangGuangbin CuiShiming HeGuodong Gao Source Type: research

Cochlear implant electrode misplacement: Incidence, evaluation, and management
Conclusions:Electrode array malpositioning is a rare, but serious and correctable complication in cochlear implant surgery. A multidisciplinary approach, including prompt audiologic evaluation and imaging, is important, particularly when benefit from the implant is limited or absent. Management of electrode arrays in the IAC may be more challenging. Laryngoscope, 2012
Source: The Laryngoscope - January 8, 2013 Category: ENT & OMF Authors: Yu‐Lan Mary Ying, Jerry W. Lin, John S. Oghalai, Robert A. Williamson Tags: Otology/Neurotology Source Type: research

Optical imaging with a high‐resolution microendoscope to identify cholesteatoma of the middle ear
Conclusions:This study demonstrates the feasibility of high‐resolution optical imaging to discriminate cholesteatoma from uninvolved middle ear mucosa based on the unique staining properties of keratin. Use of real‐time imaging may facilitate more complete extirpation of cholesteatoma by identifying areas of residual disease. Laryngoscope, 2012
Source: The Laryngoscope - January 8, 2013 Category: ENT & OMF Authors: Lauren L. Levy, Nancy Jiang, Eric Smouha, Rebecca Richards‐Kortum, Andrew G. Sikora Tags: Otology/Neurotology Source Type: research

Are Some Individuals Diagnosed With ADHD Prone to Alcohol Abuse?: Consideration of Two Possible Mediating Factors for This Susceptibility
Some studies conducted on ADHD have found a statistically significant relationship between those diagnosed with the disorder and a higher susceptibility to abuse alcohol. However, other studies have found no such correlation, or have found this to be true of only a nonstatistically significant subset of the population of individuals with ADHD. This research found an answer to what may be causing these discrepancies in findings. Various studies on ADHD have discovered both biological and cognitive differences in some individuals with ADHD that may be responsible for this predisposition toward alcohol abuse found in a subset...
Source: Journal of Attention Disorders - January 8, 2013 Category: Psychiatry Authors: Maxwell, A. Tags: Literature Review Source Type: research

Forebrain GABAergic projections to locus coeruleus in mouse
Abstract The noradrenergic locus coeruleus (LC) regulates arousal, memory, sympathetic nervous system activity and pain. Forebrain projections to LC have been characterized in rat, cat and primates, but not systematically in mouse. We surveyed mouse forebrain LC projecting neurons by examining retrogradely labeled cells following LC iontophoresis of fluorogold and anterograde LC labeling after forebrain injection of biotinylated dextran‐amine or viral tracer. Similar to other species, the central amygdalar nucleus (CAmy), anterior hypothalamus, paraventricular nucleus, and posterior lateral hypothalamic area (PLH) provid...
Source: The Journal of Comparative Neurology - January 8, 2013 Category: Neurology Authors: Eugene L. Dimitrov, Yuchio Yanagawa, Ted B. Usdin Tags: Research Article Source Type: research

Morphological analysis of the primary center receiving spatial information transferred by the waggle dance of honeybees
This study demonstrates somatotopic organization within the dSEG of the central projections of the mechanosensory neurons of the NHs. The terminals of the NH afferents in dSEG are in close apposition to those of Johnston's organ (JO) afferents. The sensory axons of both terminate in a region posterior to the crossing of the ventral intermediate tract (VIT) and the maxillary dorsal commissures I and III (MxDCI, III) in the subesophageal ganglion. These features of the terminal areas of the NH and JO afferents are common to the worker, drone, and queen castes of honeybees. Analysis of the spatial relationship between the NH ...
Source: The Journal of Comparative Neurology - January 8, 2013 Category: Neurology Authors: Hiroyuki Ai, Hiromi Hagio Tags: Research Article Source Type: research

Cell death atlas of the postnatal mouse ventral forebrain and hypothalamus: Effects of age and sex
Abstract Naturally‐occurring cell death is essential to the development of the mammalian nervous system. Although the importance of developmental cell death has been appreciated for decades, there is no comprehensive account of cell death across brain areas in the mouse. Moreover, several regional sex differences in cell death have been described inthe ventral forebrain and hypothalamus, but it is not known how widespread the phenomenon is. We used immunohistochemical detection of activated caspase‐3 to identify dying cells in the brains of male and female mice from postnatal day (P)1 to P11. Cell death density, total ...
Source: The Journal of Comparative Neurology - January 8, 2013 Category: Neurology Authors: Todd H. Ahern, Stefanie Krug, Audrey V. Carr, Elaine K. Murray, Emmett Fitzpatrick, Lynn Bengston, Jill McCutcheon, Geert J. De Vries, Nancy G. Forger Tags: Research Article Source Type: research

Differential connectivity of short‐ VS. long‐range extrinsic and intrinsic cortical inputs to perirhinal neurons
Abstract The perirhinal cortex plays a critical role in recognition and associative memory. However, the network properties that support perirhinal contributions to memory are unclear. To shed light on this question, we compared the synaptic articulation of short‐ and long‐range inputs from the perirhinal cortex or temporal neocortex with perirhinal neurons in rats. Iontophoretic injections of the anterograde tracer Phaseolus vulgaris‐leucoagglutinin (PHAL) were performed at different rostrocaudal levels of the ventral temporal neocortex or perirhinal cortex, and electron microscopic observations of anterogradely lab...
Source: The Journal of Comparative Neurology - January 8, 2013 Category: Neurology Authors: Gunes Unal, Jean‐Francois Pare, Yoland Smith, Denis Pare Tags: Research Article Source Type: research