Neuroscience
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(Source: Neurobiology of Aging)
Source: Neurobiology of Aging - March 17, 2010 Category: Neuroscience Source Type: journals
New Study Sheds Light On A Neurochemical Vulnerability That Could Contribute To Psychopathic BehaviorsEmail this article to a colleague.
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Normal individuals who scored high on a measure of impulsive/antisocial traits display a hypersensitive brain reward system, according to a brain imaging study by researchers at Vanderbilt University. The findings provide the first evidence of differences in the brain's reward system that may underlie vulnerability to what's typically referred to as psychopathy... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 17, 2010 Category: Neuroscience Tags: Psychology / Psychiatry Source Type: news
The Human Brain: Exploring Status Quo BiasEmail this article to a colleague.
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The more difficult the decision we face, the more likely we are not to act, according to new research by UCL scientists that examines the neural pathways involved in 'status quo bias' in the human brain... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 16, 2010 Category: Neuroscience Tags: Neurology / Neuroscience Source Type: news
Effect of tDCS with an extracephalic reference electrode on cardio-respiratory and autonomic functionsEmail this article to a colleague.
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Conclusions:
Applying tDCS with an extracephalic reference electrode in healthy volunteers did not significantly modulate the activity of the brainstem autonomic centres. Therefore, using an extracephalic reference electrode for tDCS appears safe in healthy volunteers, at least under similar experimental conditions. (Source: BMC Neuroscience - Latest articles)
Source: BMC Neuroscience - Latest articles - March 16, 2010 Category: Neuroscience Authors: Yves VandermeerenJacques JamartMichel Ossemann Source Type: journals
ContentsEmail this article to a colleague.
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(Source: Cortex)
Source: Cortex - March 15, 2010 Category: Neuroscience Source Type: journals
Editorial Board/Title PageEmail this article to a colleague.
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(Source: Cortex)
Source: Cortex - March 15, 2010 Category: Neuroscience Source Type: journals
Cover FigureEmail this article to a colleague.
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(Source: Cortex)
Source: Cortex - March 15, 2010 Category: Neuroscience Source Type: journals
License Agreement To Develop Treatments For Neurological Disease Announced By Brain Science InstituteEmail this article to a colleague.
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Johns Hopkins University's newly formed Brain Science Institute's NeuroTranslational Program has entered into a licensing agreement with pharmaceutical company Eisai Inc. to discover and develop small molecule glutamate carboxypeptidase II (GCPII) inhibitors... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 15, 2010 Category: Neuroscience Tags: Neurology / Neuroscience Source Type: news
Development and Validation of a Spike Detection and Classification Algorithm Aimed at Implementation on Hardware DevicesEmail this article to a colleague.
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Neurons cultured in vitro on MicroElectrode Array (MEA) devices connect to each other, forming a network. To study electrophysiological activity and long term plasticity effects, long period recording and spike sorter methods are needed. Therefore, on-line and real time analysis, optimization of memory use and data transmission rate improvement become necessary. We developed an algorithm for amplitude-threshold spikes detection, whose performances were verified with (a) statistical analysis on both simulated and real signal and (b) Big O Notation. Moreover, we developed a PCA-hierarchical classifier, evaluated on simulated...
Source: Computational Intelligence and Neuroscience - March 14, 2010 Category: Neuroscience Source Type: journals
Nightmare frequency and nightmare topics in a representative German sampleEmail this article to a colleague.
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Abstract Nightmares are defined as disturbing mental experiences that generally occur during REM sleep and often result in awakening.
Whereas the number of publications addressing nightmare frequency and psychopathology, nightmare etiology and treatment is
increasing rapidly in the last few years, nightmare content has been studied very rarely in a systematic way, especially in
adults. The present study investigated nightmare frequency and the frequency of various nightmare topics in a representative
German sample. The five most common themes were falling, being chased, paralyzed, being late, and the deaths ...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 14, 2010 Category: Neuroscience Tags: European Archives of Psychiatry and Clinical Neuroscience Source Type: journals
Neuropeptides and Large Dense Core VesiclesEmail this article to a colleague.
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We continue to be recognized by for the quantity and quality of our Neuropeptide and Neuropeptide Receptor Antibodies for studying Neurotransmission and Pain.We wanted to feature an new article referencing use of our Guinea Pig Substance Antibody. Dr. Richard Mains and his team shed light on the function and behavior of large dense corevesicles (LDCVs) concluding that under basal conditions, LDCVs move faster away from the soma than toward the soma, but fewer LDCVs travel anterograde than retrograde. Stimulation decreased average anterograde velocity and increases granule pausing. Data from antibody uptake, quantification ...
Source: Neuromics - March 13, 2010 Category: Neuroscience Tags: Substance P Antibody Large Dense Core Vesicles Neuropeptide Receptor Antibodies Neuropeptide Antibodies Substance P Antibodies LDCVs Neurotransmission Source Type: organizations
The Human Brain Processes Predictable Sensory Input In A Particularly Efficient MannerEmail this article to a colleague.
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It turns out that there is a striking similarity between how the human brain determines what is going on in the outside world and the job of scientists. Good science involves formulating a hypothesis and testing whether this hypothesis is compatible with the scientist's observations... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 13, 2010 Category: Neuroscience Tags: Neurology / Neuroscience Source Type: news
Moderate Use Of Video Games Can Be A Very Useful Educational Tool For Teaching ChildrenEmail this article to a colleague.
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Video games can have a very positive influence in the education of children, and, when used in moderation, they do not harm children's academic performance... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 12, 2010 Category: Neuroscience Tags: IT / Internet / E-mail Source Type: news
Rehabilitation After Stroke: Current State of the ScienceEmail this article to a colleague.
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Abstract Stroke rehabilitation is evolving into a clinical field based on the neuroscience of recovery and restoration. There has been
substantial growth in the number and quality of clinical trials performed. Much effort now is directed toward motor restoration
and is being led by trials of constraint-induced movement therapy. Although the results do not necessarily support that constraint-induced
movement therapy is superior to other training methods, this treatment has become an important vehicle for developing clinical
trial methods and studying the physiology underlying activity-based rehabilitation str...
Source: Current Neurology and Neuroscience Reports - March 12, 2010 Category: Neuroscience Tags: Current Neurology and Neuroscience Reports Source Type: journals
Corrigendum to "Potential mechanism of cell death in the developing rat brain induced by propofol anesthesia"International Journal of Developmental Neuroscience 27(3) 279-287 (2009).Email this article to a colleague.
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PMID: 20211421 [PubMed - in process] (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - March 12, 2010 Category: Neuroscience Authors: Pesić V, Milanović D, Tanić N, Popić J, Kanazir S, Jevtović-Todorović V, Ruzdijić S Tags: Int J Dev Neurosci Source Type: journals
Cytoarchitectonic and chemoarchitectonic characterization of the prefrontal cortical areas in the mouse.Email this article to a colleague.
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This study describes cytoarchitectonic criteria to define the prefrontal cortical areas in the mouse brain (C57BL/6 strain). Currently, well-illustrated mouse brain stereotaxic atlases are available, which, however, do not provide a description of the distinctive cytoarchitectonic characteristics of individual prefrontal areas. Such a description is of importance for stereological, neuronal tracing, and physiological, molecular and neuroimaging studies in which a precise parcellation of the prefrontal cortex (PFC) is required. The present study describes and illustrates: the medial prefrontal areas, i.e., the infralimbic, ...
Source: Brain Structure and Function - March 12, 2010 Category: Neuroscience Authors: Van De Werd HJ, Rajkowska G, Evers P, Uylings HB Tags: Brain Struct Funct Source Type: journals
Information Communication Networks in Severe Traumatic Brain Injury.Email this article to a colleague.
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In this study we explored the use of coherence and Granger causality (GC) to separate patients in minimally conscious state (MCS) from patients with severe neurocognitive disorders (SND) that show signs of awareness. We studied 16 patients, 7 MCS and 9 SND with age between 18 and 49 years. Three minutes of ongoing electroencephalographic (EEG) activity was obtained at rest from 19 standard scalp locations, while subjects were alert but kept their eyes closed. GC was formulated in terms of linear autoregressive models that predict the evolution of several EEG time series, each representing the activity of one channel. The e...
Source: Brain Topography - March 12, 2010 Category: Neuroscience Authors: Pollonini L, Pophale S, Situ N, Wu MH, Frye RE, Leon-Carrion J, Zouridakis G Tags: Brain Topogr Source Type: journals
The Genetics of Pediatric Brain TumorsEmail this article to a colleague.
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Abstract Brain tumors are the most common childhood solid malignancy and the leading cause of cancer-related death in children. Medulloblastoma,
ependymoma, supratentorial primitive neuroectodermal tumors, and pilocytic astrocytoma are the most prevalent types, all of
which are clinically, histologically, and genetically heterogeneous. Despite an incomplete molecular understanding of these
tumors, we have made significant headway in the past 5 years in identifying and classifying important genetic alterations
and pathways central to the disease process. This review summarizes our current state of knowle...
Source: Current Neurology and Neuroscience Reports - March 11, 2010 Category: Neuroscience Tags: Current Neurology and Neuroscience Reports Source Type: journals
Music Composition from the Brain Signal: Representing the Mental State by MusicEmail this article to a colleague.
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This paper proposes a method to translate human EEG into music, so as to represent mental state by music. The arousal levels of the brain mental state and music emotion are implicitly used as the bridge between the mind world and the music. The arousal level of the brain is based on the EEG features extracted mainly by wavelet analysis, and the music arousal level is related to the musical parameters such as pitch, tempo, rhythm, and tonality. While composing, some music principles (harmonics and structure) were taken into consideration. With EEGs during various sleep stages as an example, the music generated from them had...
Source: Computational Intelligence and Neuroscience - March 11, 2010 Category: Neuroscience Source Type: journals
Link Between Brain Chemical And Cognitive Decline In SchizophreniaEmail this article to a colleague.
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In one of the first such studies involving human patients with schizophrenia, researchers at UC Davis have provided evidence that deficits in a brain chemical may be responsible for some of the debilitating cognitive deficits - poor attention, memory and problem-solving abilities - that accompany the delusions and hallucinations that are the hallmarks of the disorder... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 11, 2010 Category: Neuroscience Tags: Schizophrenia Source Type: news
Sickle Cell Pain May Be From Damaged Tissues Or NervesEmail this article to a colleague.
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Researchers at the University of Illinois at Chicago have discovered the pain caused by sickle cell disease may not occur solely from damaged tissues, but also from injured nerves. The research is published in the Journal of the National Medical Association. Sickle cell disease is a hereditary disorder where red blood cells change from round to a sickle shape... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 11, 2010 Category: Neuroscience Tags: Neurology / Neuroscience Source Type: news
Researchers Discover First Direct Evidence Of Neuroplastic Changes Following Brainwave TrainingEmail this article to a colleague.
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A pioneering collaboration between two laboratories from the University of London has provided the first evidence of neuroplastic changes occurring directly after natural brainwave training... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 11, 2010 Category: Neuroscience Tags: Neurology / Neuroscience Source Type: news
SMISS Launches Online Minimally Invasive Spine ProgramsEmail this article to a colleague.
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Since its founding in 2007, the Society for Minimally Invasive Spine Surgery (SMISS) has become the pre-eminent professional society for MIS surgeons. On March 1, 2010, the organization's educational activities expanded dramatically with the launch of SMISS Highlights, an online series of CME-accredited education modules that are free of charge for spine surgeons... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 11, 2010 Category: Neuroscience Tags: Neurology / Neuroscience Source Type: news
Congenital Muscular Dystrophies: Toward Molecular Therapeutic InterventionsEmail this article to a colleague.
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Abstract Congenital muscular dystrophies (CMDs) are a clinically and genetically heterogeneous group of neuromuscular disorders that
typically present at birth or in early infancy with hypotonia, weakness, and histologic evidence of a dystrophic myopathy.
CMD biochemical types include various abnormalities of α-dystroglycan O-mannosyl glycosylation as well as defects in integrin matrix receptors, the extracellular matrix proteins laminin-α2 and collagen VI, nuclear proteins such as lamin A/C, and a protein of the endoplasmic reticulum, selenoprotein N. Current
therapies are directed mostly at supportive car...
Source: Current Neurology and Neuroscience Reports - March 11, 2010 Category: Neuroscience Tags: Current Neurology and Neuroscience Reports Source Type: journals
Advances in Pediatric NeurovirologyEmail this article to a colleague.
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Abstract Viral infections of the pediatric central nervous system (CNS) encompass a broad spectrum of both perinatally and postnatally
acquired diseases with potentially devastating effects on the developing brain. In children, viral infections have been associated
with chronic encephalopathy, encephalitis, demyelinating disease, tumors, and epilepsy. Older diagnostic techniques of biopsy,
viral culture, electron microscopy, gel-based polymerase chain reaction (PCR), and viral titer quantification are being replaced
with more rapid, sensitive, and specific real-time and microarray-based PCR technologies. Adv...
Source: Current Neurology and Neuroscience Reports - March 11, 2010 Category: Neuroscience Tags: Current Neurology and Neuroscience Reports Source Type: journals
A visual distracter task during adaptation reduces the proprioceptive movement aftereffect.Email this article to a colleague.
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Visual processing of basic perceptual attributes depends on attention. This has been well documented since the surprising initial report on attentional modulation of the visual motion aftereffect (Chaudhuri 1990). Here, we investigate proprioception and show for the first time that attention modulates adaptation to perceived limb movement. We used biceps vibration to induce illusory forearm extension in 10 participants and measured the aftereffect-perceived movement in the opposite direction. The aftereffect was largest when participants focused on the illusory extension during the adaptation period. To divert attentio...
Source: Experimental Brain Research - March 11, 2010 Category: Neuroscience Authors: Seizova-Cajic T, Azzi R Tags: Exp Brain Res Source Type: journals
Forthcoming conferences.Email this article to a colleague.
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PMID: 20221668 [PubMed - as supplied by publisher] (Source: Cognitive Processing)
Source: Cognitive Processing - March 11, 2010 Category: Neuroscience Tags: Cogn Process Source Type: journals
Acalculia in a patient with severe language disturbances: how do we test it?Email this article to a colleague.
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The present paper describes a case of a patient with severe Wernicke aphasia, which when tested with a number processing and calculation battery adapted to his difficulties showed remarkable arithmetic skills. These findings suggest that the patients with severe cognitive impairments (e.g., aphasia, apraxia) should be tested with batteries adapted to their disturbances because using a standard test may bias the results.
PMID: 20221669 [PubMed - as supplied by publisher] (Source: Cognitive Processing)
Source: Cognitive Processing - March 11, 2010 Category: Neuroscience Authors: Rosca EC Tags: Cogn Process Source Type: journals
Role of prostaglandin E receptor subtypes EP2 and EP4 in autocrine and paracrine functions of vascular endothelial growth factor in the inner earEmail this article to a colleague.
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Conclusions:
These findings demonstrate that EP2 and EP4 agonists stimulate VEGF production in the inner ear, particularly in the spiral ganglions. Moreover, the Flt-1 and Flk-1 expression observed in the present study suggests that VEGF has autocrine and paracrine actions in the cochlea. Thus, EP2 and EP4 might be involved in the mechanisms underlying the therapeutic effects of PGE1 on acute sensorineural hearing loss via VEGF production. (Source: BMC Neuroscience - Latest articles)
Source: BMC Neuroscience - Latest articles - March 11, 2010 Category: Neuroscience Authors: Ryusuke HoriTakayuki NakagawaNorio YamamotoKiyomi HamaguchiJuichi Ito Source Type: journals
Top-down and bottom-up modulation in processing bimodal face/voice stimuli.Email this article to a colleague.
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Conclusions:
Our data demonstrate that in a gender categorisation task the processing of faces dominate over the processing of voices. Brain activity showed different modulation by top-down and bottom-up information. Top-down influences modulated early brain activity whereas bottom-up interactions occurred relatively late. (Source: BMC Neuroscience - Latest articles)
Source: BMC Neuroscience - Latest articles - March 11, 2010 Category: Neuroscience Authors: Marianne LatinusRufin VanRullenMargot Taylor Source Type: journals
Utility of Skin Biopsy to Evaluate Peripheral NeuropathyEmail this article to a colleague.
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Abstract Skin biopsy for epidermal nerve fiber analysis provides an important objective test for the diagnosis of peripheral neuropathy,
particularly small fiber sensory neuropathy (SFSN). The determination of epidermal nerve fiber density (ENFD) is reliable,
with high diagnostic specificity and good sensitivity. Because of false negatives, biopsy results must be interpreted in conjunction
with neurologic findings and laboratory results, including objective tests of sensory and autonomic function. SFSN most commonly
is length dependent and is idiopathic in about half the patients. Biopsy of a proximal site (...
Source: Current Neurology and Neuroscience Reports - March 10, 2010 Category: Neuroscience Tags: Current Neurology and Neuroscience Reports Source Type: journals
Brain Activity Predicts Emotional Resiliency Following A Fight With A PartnerEmail this article to a colleague.
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Common wisdom tells us that for a successful relationship partners shouldn't go to bed angry. But new research from a psychologist at Harvard University suggests that brain activity - specifically in the region called the lateral prefrontal cortex - is a far better indicator of how someone will feel in the days following a fight with his or her partner... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 10, 2010 Category: Neuroscience Tags: Psychology / Psychiatry Source Type: news
MSRC Comments On Stanford University Reportedly Halting CCSVI Treatments After Two Serious Adverse EventsEmail this article to a colleague.
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Researchers at Stanford University have halted treatments for chronic cerebrospinal venous insufficiency (CCSVI) due to two serious adverse events which may not have been accurately reported in some of the press... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 10, 2010 Category: Neuroscience Tags: Neurology / Neuroscience Source Type: news
Anthropologist/Neuroscientist Team Propose That Religion Is Ubiquitous And Persistent Because The Human Brain Needs ItEmail this article to a colleague.
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In the fractious debate on the existence of God and the nature of religion, two distinguished scientists radically alter the discussion... (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 10, 2010 Category: Neuroscience Tags: Psychology / Psychiatry Source Type: news
Bimanual movement control is moderated by fixation strategies.Email this article to a colleague.
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Our study examined the effects of performing a pointing movement with the left hand on the kinematics of a simultaneous grasping movement executed with the right hand. We were especially interested in the question of whether both movements can be controlled independently or whether interference effects occur. Since previous studies suggested that eye movements may play a crucial role in bimanual movement control, the effects of different fixation strategies were also studied. Human participants were either free to move their eyes (Experiment 1) or they had to fixate (Experiment 2) while doing the task. The results show...
Source: Experimental Brain Research - March 10, 2010 Category: Neuroscience Authors: Hesse C, Nakagawa TT, Deubel H Tags: Exp Brain Res Source Type: journals
Depression research: where are we now?Email this article to a colleague.
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Extensive studies have led to a variety of hypotheses for the molecular basis of depression and related mood disorders, but a definite pathogenic mechanism has yet to be defined. The monoamine hypothesis, in conjunction with the efficacy of antidepressants targeting monoamine systems, has long been the central topic of depression research. While it is widely embraced that the initiation of antidepressant efficacy may involve acute changes in monoamine systems, apparently, the focus of current research is moving toward molecular mechanisms that underlie long-lasting downstream changes in the brain after chronic antidepressa...
Source: Molecular Brain - March 10, 2010 Category: Neuroscience Authors: Saebom LeeJaehoon JeongYongdo KwakSang Ki Park Source Type: journals
CREB's control of intrinsic and synaptic plasticity: implications for CREB-dependent memory models.Email this article to a colleague.
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The activation of cAMP-response element binding protein (CREB)-dependent gene expression seems a crucial step in the molecular cascade that mediates the formation of long-lasting memories. This view is based both on correlative evidence and on functional assays that demonstrate, through loss- and gain-of-function experiments, the impact of CREB manipulation on memory performance. Mechanistically, CREB's role in memory is thought to be a consequence of its participation in long-term forms of synaptic plasticity. Recent studies demonstrate that CREB, in addition to synaptic plasticity, also modulates the intrinsic excita...
Source: Trends in Neurosciences - March 9, 2010 Category: Neuroscience Authors: Benito E, Barco A Tags: Trends Neurosci Source Type: journals
Reactive grip force control in persons with cerebellar stroke: effects on ipsilateral and contralateral hand.Email this article to a colleague.
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This study investigates the cerebellar contribution to reactive grip control by examining differences between (22-48 years) subjects with focal cerebellar lesion due to ischaemic stroke (CL) and healthy subjects (HS). The subjects used a pinch grip to grasp and restrain an instrumented handle from moving when it was subject to unpredictable load forces of different rates (2, 4, 8, 32 N/s) or amplitudes (1, 2, 4 N). The hand ipsilateral to the lesion of the cerebellar subjects showed delayed and more variable response latencies, e.g., 278 +/- 162 ms for loads delivered at 2 N/s, compared to HS 180 +/- 53 ms (P = 0.005). The...
Source: Experimental Brain Research - March 9, 2010 Category: Neuroscience Authors: Anens E, Kristensen B, Häger-Ross C Tags: Exp Brain Res Source Type: journals
Changes in corticospinal excitability evoked by common peroneal nerve stimulation depend on stimulation frequency.Email this article to a colleague.
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This study was designed to determine the effect of different frequencies of NMES applied over the common peroneal nerve on changes in CS excitability for the tibialis anterior (TA) muscle. We hypothesized that higher frequencies of stimulation would produce larger increases in CS excitability than lower frequencies. NMES was applied at 10, 50, 100, or 200 Hz during separate sessions held at least 48 h apart. The stimulation was delivered in a 20 s on, 20 s off cycle for 40 min using a 1 ms pulse width. The intensity of stimulation was set to evoke an M-wave in response to a single pulse that was 15% of the maximal M-wave. ...
Source: Experimental Brain Research - March 9, 2010 Category: Neuroscience Authors: Mang CS, Lagerquist O, Collins DF Tags: Exp Brain Res Source Type: journals
The role of the right temporoparietal junction in intersensory conflict: detection or resolution?Email this article to a colleague.
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The right temporoparietal junction (rTPJ) is a polysensory cortical area that plays a key role in perception and awareness. Neuroimaging evidence shows activation of rTPJ in intersensory and sensorimotor conflict situations, but it remains unclear whether this activity reflects detection or resolution of such conflicts. To address this question, we manipulated the relationship between touch and vision using the so-called mirror-box illusion. Participants' hands lay on either side of a mirror, which occluded their left hand and reflected their right hand, but created the illusion that they were looking directly at their...
Source: Experimental Brain Research - March 9, 2010 Category: Neuroscience Authors: Papeo L, Longo MR, Feurra M, Haggard P Tags: Exp Brain Res Source Type: journals
Tyrosine Phosphorylation of Apoptotic Proteins During Hyperoxia in Mitochondria of the Cerebral Cortex of Newborn Piglets.Email this article to a colleague.
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The present study tests the hypothesis that hyperoxia results in increased tyrosine phosphorylation of apoptotic proteins Bcl-2, Bcl-xl, Bax & Bad in the mitochondrial fraction of the cerebral cortex of newborn piglets. Twelve newborn piglets were divided into normoxic [Nx, n = 6], exposed to a FiO(2) of 0.21 for 1 h and hyperoxic [Hyx, n = 6], exposed to FiO(2) of 1.0 for 1 h. PaO(2) in Hyx group was maintained at 400 mmHg while the Nx group was kept at 80 to100 mmHg. The density (O.D.x mm(2)) of phosphorylated Bcl2 protein on westernblot was 19.3 +/- 3.6 in Nx and 41.5 +/- 18.3 in Hyx, (P < 0.05). The density ...
Source: Neurochemical Research - March 9, 2010 Category: Neuroscience Authors: Mudduluru M, Zubrow AB, Ashraf QM, Delivoria-Papadopoulos M, Mishra OP Tags: Neurochem Res Source Type: journals
Flavonoids and Astrocytes Crosstalking: Implications for Brain Development and Pathology.Email this article to a colleague.
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Flavonoids are naturally occurring polyphenolic compounds that are present in a variety of fruits, vegetables, cereals, tea, and wine, and are the most abundant antioxidants in the human diet. Evidence suggests that these phytochemicals might have an impact on brain pathology and aging; however, neither their mechanisms of action nor their cell targets are completely known. In the mature mammalian brain, astroglia constitute nearly half of the total cells, providing structural, metabolic, and trophic support for neurons. During the past few years, increasing knowledge of these cells has indicated that astrocytes are pi...
Source: Neurochemical Research - March 9, 2010 Category: Neuroscience Authors: Nones J, Stipursky J, Costa SL, Gomes FC Tags: Neurochem Res Source Type: journals
Multimodal investigations of trans-endothelial cell trafficking under condition of disrupted blood-brain barrier integrityEmail this article to a colleague.
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Conclusions:
Our data show that targeted CNS cell therapy requires blood-brain barrier disruption. MRI-detectable cytotoxic anti-neoplastic cells can be forced to transverse the BBB and accumulate in the perivascular space. The virtual absence of toxicity, the high anti-tumor activity of TALL-104, and the clinical feasibility of human osmotic BBBD suggest that this approach may be adopted to treat brain or spinal cord tumors. In addition, BBBD may favor CNS entry of other cells that normally lack CNS tropism. (Source: BMC Neuroscience - Latest articles)
Source: BMC Neuroscience - Latest articles - March 9, 2010 Category: Neuroscience Authors: Nicola MarchiQingshan TengMinh NguyenLinda FranicNirav DesaiThomas MasarykPeter RasmussenSilvia TrasciattiDamir JanigroUndefined Undefined Source Type: journals
Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependenceEmail this article to a colleague.
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Conclusions:
It is known that chronic morphine treatment decreases dendritic arborization and hippocampal neurogenesis, and Wnt proteins are essential for these processes. We therefore propose that the morphine-mediated MOR/GPR177 interaction may result in decreased Wnt secretion in the CNS, resulting in atrophy of dendritic arbors and decreased neurogenesis. Our results demonstrate a previously unrecognized role for GPR177 in regulating cellular response to opioid drugs. (Source: BMC Neuroscience - Latest articles)
Source: BMC Neuroscience - Latest articles - March 9, 2010 Category: Neuroscience Authors: Jay JinSaranya KittanakomVictoria WongBeverly ReyesElisabeth Van BockstaeleIgor StagljarWade BerrettiniRobert Levenson Source Type: journals
Non-neuronal cells, inflammation and epilepsy (Commentary on Aronica et al.)Email this article to a colleague.
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(Source: European Journal of Neuroscience)
Source: European Journal of Neuroscience - March 9, 2010 Category: Neuroscience Authors: Paolo F. Fabene Source Type: journals
59. Development of cognitive ability of children aged 2–3 years applying the “doll mother” modelEmail this article to a colleague.
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Introduction: In the development of children’s cognitive abilities making doll models plays an important role. Aim: Aim of this work was to develop children’s cognitive ability through visual art. (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 8, 2010 Category: Neuroscience Authors: B. Popovic, J. Milenovic, S. Ciprovac, S. Golubovic Tags: Society Proceedings: 9th Congress of Clinical Neurophysiology Society of Serbia and Montenegro with International Participation, Belgrade, Serbia, October 15-17, 2009 Source Type: journals
58. Possible prenatal causes for clinical expression of autismEmail this article to a colleague.
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Autism is severe developmental disorder with onset around age of three years. Main characteristics of autistic children are problems with social interaction, emotional correspondence and difficulty with verbal and nonverbal communication. One of the most intriguing questions is the possible reasons causing the expression of autism. Aim of this study was to evaluate the possible prenatal causes for clinical expression of autism. (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 8, 2010 Category: Neuroscience Authors: B. Popovic, M. Sekularac, L. Marjanovic Tags: Society Proceedings: 9th Congress of Clinical Neurophysiology Society of Serbia and Montenegro with International Participation, Belgrade, Serbia, October 15-17, 2009 Source Type: journals
57. Anxiety in the patients with rheumatoid arthritisEmail this article to a colleague.
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The aim was to identify the frequency and level of anxiety in the patients with rheumatoid arthritis (RA). In 60 patients with RA, aged 49.87±7.56 yrs., we evaluated: disease activity by DAS28 score, functional ability by the HAQ, and anxiety by Spielberger test (state and trai anxiety). (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 8, 2010 Category: Neuroscience Authors: S. Tomasevic-Todorović, K. Boskovic, D. Filipovic, N. Naumović, S. Pantelinac Tags: Society Proceedings: 9th Congress of Clinical Neurophysiology Society of Serbia and Montenegro with International Participation, Belgrade, Serbia, October 15-17, 2009 Source Type: journals
56. The effect of pain on cognitive abilities of patients with rheumatoid arthritisEmail this article to a colleague.
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The aim was to examine the impact of the pain on the cognitive abilities in the patients with rheumatoid arthritis (RA). Material and methods: we investigated 60 patients with RA and 30 healthy subjects. The intensity of pain was determined by VAS, cognitive abilities by the Wechsler memory scale, functional ability by HAQ questionnaire, and disease activity by DAS28 score. (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - March 8, 2010 Category: Neuroscience Authors: S. Tomasevic-Todorović, D. Filipovic, K. Boskovic Tags: Society Proceedings: 9th Congress of Clinical Neurophysiology Society of Serbia and Montenegro with International Participation, Belgrade, Serbia, October 15-17, 2009 Source Type: journals
