Neuroscience Top 20This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

High Protein Diet Shrinks BrainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
One of the many reasons to pick a low-calorie, low-fat diet rich in vegetables, fruits, and fish is that a host of epidemiological studies have suggested that such a diet may delay the onset or slow the progression of Alzheimer's disease (AD). Now a study published in BioMed Central's open access journal Molecular Neurodegeneration tests the effects of several diets, head-to-head, for their effects on AD pathology in a mouse model of the disease. (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - October 21, 2009 Category: Neuroscience Tags: Alzheimer's / Dementia Source Type: news

Possible Link Between Epstein-Barr Virus And Progression Of MSEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Epstein-Barr virus (EBV), the pathogen that causes mononucleosis, appears to play a role in the neurodegeneration that occurs in persons with multiple sclerosis, researchers at the University at Buffalo and the University of Trieste, Italy, have shown. Multiple sclerosis (MS) is an autoimmune disease that can cause major disability. There currently is no cure. (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - March 4, 2009 Category: Neuroscience Tags: Multiple Sclerosis Source Type: news

In Fight Against Deadly Brain Tumors Common Virus May Serve As Target For VaccineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
By targeting a common virus, doctors may be able to extend the lives of patients diagnosed with the most prevalent and deadly type of brain tumor, according to a study led by researchers in Duke's Preston Robert Tisch Brain Tumor Center.A type of herpes virus called human cytomegalovirus (CMV) is found in up to 80 percent of Americans, though the virus normally produces very few clinical symptoms, is dormant, and usually undetectable in most people. (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - May 18, 2008 Category: Neuroscience Source Type: news

Localization of NADPH oxidase in sympathetic and sensory ganglion neurons and perivascular nerve fibersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Superoxide anion (O2−•) production was previously reported to be increased in celiac ganglia (CG) during DOCA–salt hypertension, possibly via activation of the reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase. This suggested a role for neuronal NADPH oxidase in autonomic neurovascular control. However, the expression and localization of NADPH oxidase in the peripheral neurons are not fully known. The purpose of this study was to examine the subcellular localization of NADPH oxidase in sympathetic and sensory ganglion neurons and perivascular nerve fibers. In rat CG, p22phox and neuropepti...
Source: Autonomic Neuroscience: Basic and Clinical - November 2, 2009 Category: Neuroscience Authors: Xian Cao, Stacie L. Demel, Mark T. Quinn, James J. Galligan, David Kreulen Tags: Basic Autonomic Neuroscience Source Type: journals

Optimizing brain processingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Neuroscience 12, 1359 (2009). doi:10.1038/nn1109-1359 Author: Alexander Thiele Cholinergic neurons in the basal forebrain enable alert and attending brain states. A study now shows how basal forebrain activity increases coding abilities of cortical neurons and at what stages these changes occur. (Source: Nature Neuroscience)
Source: Nature Neuroscience - October 27, 2009 Category: Neuroscience Authors: Alexander Thiele Tags: News and Views Source Type: journals

Hospital For Special Surgery Establishes A Comprehensive Spine Care InstituteEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hospital for Special Surgery announced the establishment of one of the most comprehensive centers of excellence in the country for the treatment of all nonoperative and operative spine disorders. The newly formed Spine Care Institute brings together a multidisciplinary team of experts in an academic setting to ensure that every need is met for a patient with a spine condition. Back pain is a widespread problem affecting 8 out of 10 people in the U.S. (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - November 15, 2009 Category: Neuroscience Tags: Neurology / Neuroscience Source Type: news

Neurological disorders: Connectivity in RettEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nature Reviews Neuroscience 10, 765 (2009). doi:10.1038/nrn2744 Author: Claudia Wiedemann Rett syndrome is a neurodevelopmental disorder that manifests in early childhood and is caused by mutations in the gene encoding methyl-CpG-binding protein 2 (MECP2). Previous studies have shown that synaptic input to layer 5 pyramidal neurons is abnormal in Mecp2-null mice, (Source: Nature Reviews Neuroscience)
Source: Nature Reviews Neuroscience - October 13, 2009 Category: Neuroscience Authors: Claudia Wiedemann Tags: Research Highlight Source Type: journals

Influence of bariatric surgery on indices of cardiac autonomic controlEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study therefore sought to assess longitudinal changes in indices of cardiac autonomic control following two types of bariatric procedure, laparascopic gastric banding (LGB) and biliopancreatic diversion (BPD).Methods: Eleven morbidly obese subjects aged 47.8±7.9years (mean±SD) with BMI 48.2±6.9kg·m-2 underwent weight-reduction surgery: five received BPD and six received LGB. Holter ECG was recorded and HRV was quantified together with a QT variability index (QTVI), a complexity index (SampEn), and a fractal (scaling) index (DFAα). Repeated measures ANOVA compared the indices for the two groups as a function of ti...
Source: Autonomic Neuroscience: Basic and Clinical - November 2, 2009 Category: Neuroscience Authors: I. Alam, M.J. Lewis, K.E. Lewis, J.W. Stephens, J.N. Baxter Tags: Clinical Autonomic Neuroscience Source Type: journals

Mechanism of action in CBT (MAC): methods of a multi-center randomized controlled trial in 369 patients with panic disorder and agoraphobiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Cognitive behavioral therapy (CBT) is efficacious for panic disorder with agoraphobia (PD/A). Nevertheless, the active ingredients of treatment and the mechanisms through which CBT achieves its effects remain largely unknown. The mechanisms of action in CBT (MAC) study was established to investigate these questions in 369 patients diagnosed with PD/A. The MAC study utilized a multi-center, randomized controlled design, with two active treatment conditions in which the administration of exposure was varied, and a wait-list control group. The special feature of MAC is the way in which imbedded experim...
Source: European Archives of Psychiatry and Clinical Neuroscience - October 29, 2009 Category: Neuroscience Tags: European Archives of Psychiatry and Clinical Neuroscience Source Type: journals

The assessment of the phenomenology of sleep paralysis: the Unusual Sleep Experiences Questionnaire (USEQ).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Previous research has found a relationship between sleep paralysis (SP) and anxiety states and higher rates have been reported among certain ethnic groups. To advance the cross-cultural study of SP, we developed a brief assessment instrument (which can be self-administered), the Unusual Sleep Experiences Questionnaire (USEQ). In this article, we report on a pilot study with the USEQ in a sample of 208 college students. The instrument was easily understood by the participants, with one quarter reporting at least one lifetime episode of SP. As in previous studies, SP was associated with anxiety (in particular, panic atta...
Source: CNS Neuroscience and Therapeutics - August 22, 2009 Category: Neuroscience Authors: Paradis C, Friedman S, Hinton DE, McNally RJ, Solomon LZ, Lyons KA Tags: CNS Neurosci Ther Source Type: journals

Paraneoplastic Cerebellar Degeneration Mimicking Acute Post-Infectious Cerebellitis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Acute cerebellitis is a monophasic non-progressive encephalitis restricted to the cerebellum, while paraneoplastic cerebellar degeneration is a subacute progressive disorder, which may either accompany or herald Hodgkin's disease. In the present report, we describe a young man with clinical and laboratory features of acute post-infectious cerebellitis in whom the progressive relapsing course subsequently led to the diagnosis of Hodgkin's disease. Dynamic changes observed on repeated MRIs during the protracted clinical course imply the presence of early active inflammation and subsequent neuronal atrophy. PMID: 1972...
Source: Cerebellum - September 1, 2009 Category: Neuroscience Authors: Karmon Y, Inbar E, Cordoba M, Gadoth N Tags: Cerebellum Source Type: journals

Galantamine-ER for cognitive dysfunction in bipolar disorder and correlation with hippocampal neuronal viability: a proof-of-concept study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Bipolar subjects had cognitive dysfunction; treatment with Galantamine-ER was associated with improved cognition and with increases in neuronal viability and normalization of lipid membrane metabolism in the left hippocampus. This study was registered on ClinicalTrials.gov (NCT00181636). PMID: 19889129 [PubMed - in process] (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - November 7, 2009 Category: Neuroscience Authors: Iosifescu DV, Moore CM, Deckersbach T, Tilley CA, Ostacher MJ, Sachs GS, Nierenberg AA Tags: CNS Neurosci Ther Source Type: journals

Electrical acupuncture reduces the inhibitory effect of butylscopolamine on gastric motilityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Electrical acupuncture of lower limb ST36 point reportedly facilitates gastric activity in healthy subjects. We studied the effect of this stimulation on butylscopolamine-induced inhibition of gastric motility in healthy subjects. Physiological post-prandial gastric activity was observed for 30 min after food ingestion (Ensure liquid(tm), 1.5 ml/kg of body weight (BW) and water, 1.5 ml/kg BW) with continuous ultrasonographic recordings (B-mode, 5 MHz convex probe) of the gastric antrum and external electrogastrography (EGG) for 40 min in 10 healthy subjects (control group). Butylscopolamine (4 μg/kg BW) was administ...
Source: Autonomic Neuroscience: Basic and Clinical - November 2, 2009 Category: Neuroscience Authors: Nauru Shimizu, Eiichi Chihara Tags: Abstracts: The Japanese Autonomic Nervous System Source Type: journals

Vagus nerve stimulation-induced bradyarrhythmias in ratsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: The autonomic consequences of seizures can be severe. Death can follow from autonomic overactivity that causes a parasympathetically mediated bradyarrhythmia. We studied the cardiovascular consequences of unilateral and bilateral stimulation of the distal segments of transected vagus nerve in rats anesthetized with urethane. The range of stimulation rates tested is comparable to the firing rates observed in vagus nerve during seizures. There was a consistent inverse relation between stimulus rate and heart rate with nodal block appearing at 5–10Hz and minimum HR levels (cardiac standstill) occurring at 50Hz. Ca...
Source: Autonomic Neuroscience: Basic and Clinical - November 2, 2009 Category: Neuroscience Authors: Harumi Hotta, Jason Lazar, Rena Orman, Kiyomi Koizumi, Kanako Shiba, Haroon Kamran, Mark Stewart Tags: Basic Autonomic Neuroscience Source Type: journals

Findings That Should Speed The Development Of Drugs For Parkinson's DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Australian scientists have significantly advanced our understanding of dopamine release from nerve cells, findings that should speed the development of more effective drugs for treating Parkinson's Disease. People with Parkinson's Disease suffer from muscle rigidity, tremor, a slowing of physical movement and, in extreme cases, a loss of physical movement. These primary symptoms are caused by the loss of dopamine producing nerve cells in the brain. (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - November 19, 2009 Category: Neuroscience Tags: Parkinson's Disease Source Type: news

The Protein Srebp2 Drives Cholesterol Formation In Prion-Infected Neuronal Cells Which May Promote Prion-Dependent DiseasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Prions are causing fatal and infectious diseases of the nervous system, such as the mad cow disease (BSE), scrapie in sheep or Creutzfeldt-Jakob disease in humans. Scientists of Helmholtz Zentrum MÃ¼nchen and Technische UniversitÃ¤t MÃ¼nchen have now succeeded in elucidating another disease mechanism of prion diseases: The prion-infected cell changes its gene expression and produces increased quantities of cholesterol. Prions need this for their propagation. (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - November 19, 2009 Category: Neuroscience Tags: Neurology / Neuroscience Source Type: news

The Formation Of Lasting Memories Deciphered By ScientistsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Researchers at Karolinska Institutet have discovered a mechanism that controls the brain's ability to create lasting memories. In experiments on genetically manipulated mice, they were able to switch on and off the animals' ability to form lasting memories by adding a substance to their drinking water. The findings, which are published in the scientific journal PNAS, are of potential significance to the future treatment of Alzheimer's and stroke. (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - November 11, 2009 Category: Neuroscience Tags: Alzheimer's / Dementia Source Type: news

Potential mechanisms involved in the prevention of neurodegenerative diseases by lithium.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Lithium is a monovalent cation that was introduced in 1949 by John Cade for the treatment of bipolar disorder. Clinical reports and subsequent studies confirmed this application and the beneficial effects of this compound. However, over the last 15 years, various authors have also demonstrated the neuroprotective effects of lithium against several neurotoxic paradigms. Thus, experimental studies in neuronal cell cultures and animal models of Alzheimer disease and others pathologies have provided strong evidence for the potential benefits of lithium. The main mechanism underlying its neuroprotective effects is thought t...
Source: CNS Neuroscience and Therapeutics - November 7, 2009 Category: Neuroscience Authors: Camins A, Verdaguer E, Junyent F, Yeste-Velasco M, Pelegrí C, Vilaplana J, Pallás M Tags: CNS Neurosci Ther Source Type: journals

Correlations between peripheral blood mononuclear cell production of BDNF, TNF-alpha, IL-6, IL-10 and cognitive performances in multiple sclerosis patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion our study shows a correlation between low BDNF and high IL-6 production by PBMCs and poorer performances in cognitive tasks in RRMS patients suggesting a possible role of these factors in cognitive impairment in MS. © 2009 Wiley-Liss, Inc. (Source: Journal of Neuroscience Research)
Source: Journal of Neuroscience Research - November 2, 2009 Category: Neuroscience Authors: A.K. Patanella, M. Zinno, D. Quaranta, V. Nociti, G. Frisullo, G. Gainotti, P.A. Tonali, A.P. Batocchi, C. Marra Source Type: journals

FDA Grants Approval To Talecris Biotherapeutics For Gamunex(R) As A Treatment For Neurological Disorder CIDP In The United StatesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Talecris Biotherapeutics, Inc. announced the U.S. Food and Drug Administration (FDA) has granted approval for Gamunex (Immune Globulin Intravenous [Human], 10% Caprylate/Chromatography Purified) as a treatment for chronic inflammatory demyelinating polyneuropathy (CIDP). CIDP is a debilitating neurological disorder that results in muscle weakness and fatigue, which can lead to severe impairment of motor skills. (Source: Neurology / Neuroscience News From Medical News Today)
Source: Neurology / Neuroscience News From Medical News Today - September 17, 2008 Category: Neuroscience Tags: Neurology / Neuroscience Source Type: news