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Contrast Enhancement and Histopathological Findings in Vestibular SchwannomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a case of a large vestibular schwannoma with heterogeneous contrast uptake on MRI. Using neuronavigation, histological samples were obtained during surgery from an area with homogeneous contrast uptake and from a central tumor portion without contrast enhancement on MRI. Intraoperative investigation found no evidence of necrotic tumor, and histopathological examination revealed an active tumor in both sections, with no central necrosis. This finding illustrates the surgical experience that “necrotic tumor areas” on MRI may not be consistent with intraoperative findings. Lack of contrast uptake in pre...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - November 21, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Formation of Two Consecutive Intrathecal Catheter Tip Granulomas within Nine MonthsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Zentralbl NeurochirDOI: 10.1055/s-0029-1202359AbstractThe formation of catheter tip granulomas is an increasingly observed serious complication of intrathecally administered medication. This complication, which is frequently associated with neurological disturbances, has previously been attributed to high dosages and high concentrations of intrathecal morphine. Much less commonly, intrathecal hydromorphone and intrathecal baclofen have also been associated with intrathecal granuloma formation. In the current case, we report a patient who developed her first catheter tip granuloma after 20 months of intrathecal morphine. Af...
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - November 19, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

Endoscopic Anatomy for Transnasal Transsphenoidal Pituitary Surgery in the Presence of a Persistent Trigeminal ArteryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Zentralbl Neurochir 2009; 70: 207-210DOI: 10.1055/s-0028-1093354Abstract Endoscopic procedures are becoming increasingly important for transnasal transsphenoidal approaches to the skull base and particularly for pituitary surgery. A persistent trigeminal artery (PTA) is rare. Its presence, if it goes unnoticed or if the surgeon is not aware of such a variant, may endanger the success of surgery.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - November 18, 2009 Category: Neurosurgery Tags: Case Report Source Type: journals

The neurology of olfactionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Berendse, H W Tags: PostScript Source Type: journals

The old age psychiatry handbook. A practical guideEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Philpot, M P Tags: PostScript Source Type: journals

Epilepsy in womenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Jackson, M Tags: PostScript Source Type: journals

Behavioural abnormalities associated with rapid deterioration of language functions in semantic dementia respond to sertralineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Prodan, C I, Monnot, M, Ross, E D Tags: PostScript Source Type: journals

Posterior circulation strokes without systemic involvement as the presenting feature of Fabry diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Gregoire, S M, Brown, M M, Collas, D M, Jacob, P, Lachmann, R H, Werring, D J Tags: PostScript Source Type: journals

Characteristics of abnormal eating behaviours in frontotemporal lobar degeneration: a cross-cultural surveyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Shinagawa, S, Ikeda, M, Nestor, P J, Shigenobu, K, Fukuhara, R, Nomura, M, Hodges, J R Tags: PostScript Source Type: journals

Immunotherapy: responsive autoimmune encephalopathy associated with bullous pemphigoidEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Soni, A, Irani, S R, Lang, B, Taghipour, K, Mann, R, Vincent, A, Collins, D Tags: PostScript Source Type: journals

Genetic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Kovacs, G G, Horvath, S, Strobel, T, Puskas, M, Bakos, A, Summers, D M, Will, R G, Budka, H Tags: PostScript Source Type: journals

Johann Cristian Reil on the 200th anniversary of the first description of the insula (1809)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Fusar-Poli, P, Howes, O, Borgwardt, S Tags: Historical notes Source Type: journals

Clinical and mutational spectrum of limb-girdle muscular dystrophy type 2I in 11 French patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This study reveals inter- and intrafamilial phenotypic variability in LGMD2I, with a preponderance of myocardiopathy and restrictive respiratory insufficiency. It also demonstrates central nervous involvement, probably associated with changes in -dystroglycan expression in the brain. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Bourteel, H, Vermersch, P, Cuisset, J-M, Maurage, C-A, Laforet, P, Richard, P, Stojkovic, T Tags: Genetics, Muscle disease, Neuroimaging, Neuromuscular disease, Stroke, Musculoskeletal syndromes Short reports Source Type: journals

Frequency and phenotype of SPG11 and SPG15 in complicated hereditary spastic paraplegiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: TCC seems to be the best phenotypic predictor for SPG11 as well as SPG15. No clinical features could discriminate between SPG11 and SPG15. Therefore, priority of genetic testing should be driven by mutation frequency that appears to be substantially higher in SPG11 than in SPG15. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Schule, R, Schlipf, N, Synofzik, M, Klebe, S, Klimpe, S, Hehr, U, Winner, B, Lindig, T, Dotzer, A, Riess, O, Winkler, J, Schols, L, Bauer, P Tags: Genetics, Brain stem / cerebellum, Neuromuscular disease, Peripheral nerve disease, Child and adolescent psychiatry Short reports Source Type: journals

Long-term mortality and vascular event risk after aneurysmal subarachnoid haemorrhageEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: SAH patients who recover to a functional independent state have an excess mortality compared with the general population. The risk of vascular events after SAH is lower than after minor stroke, but higher than the population risks reported in the literature. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Wermer, M J H, Greebe, P, Algra, A, Rinkel, G J E Tags: Stroke Short reports Source Type: journals

Bilateral periventricular nodular heterotopia in France: frequency of mutations in FLNA, phenotypic heterogeneity and spectrum of mutationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bilateral periventricular nodular heterotopia (BPNH) is the most common form of periventricular heterotopia. Mutations in FLNA, encoding filamin A, are responsible for the X linked dominant form of BPNH (FLNA-BPNH). Recently, atypical phenotypes including BPNH with Ehlers–Danlos syndrome (BPNH-EDS) have been recognised. A total of 44 FLNA mutations have so far been reported in this phenotype. Most of these mutations lead to a truncated protein, but few missense mutations have also been described. Here, the results of a mutation screening conducted in a series of 32 BPNH patients with the identification of 12 novel po...
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Sole, G, Coupry, I, Rooryck, C, Guerineau, E, Martins, F, Deves, S, Hubert, C, Souakri, N, Boute, O, Marchal, C, Faivre, L, Landre, E, Debruxelles, S, Dieux-Coeslier, A, Boulay, C, Chassagnon, S, Michel, V, Routon, M-C, Toutain, A, Philip, N, Lacombe, D, Tags: Genetics, Connective tissue disease Short reports Source Type: journals

Tongue pseudohypertrophy in idiopathic hypoglossal nerve palsyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Holle, D, Kastrup, O, Sheu, S-Y, Obermann, M Tags: Immunology (including allergy), Cranial nerves, Multiple sclerosis, Muscle disease, Neuromuscular disease, Peripheral nerve disease, Radiology, Musculoskeletal syndromes, Surgical diagnostic tests Neurological pictures Source Type: journals

Impact of posterior communicating artery on basilar artery steno-occlusive diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Fetal-variant PcoA appears to act as a safeguard against ischaemic insult in acute stroke victims involving the brainstem with BA occlusive disease. This result can be explained by the fact that patients with fetal-variant PcoA have a smaller area of posterior circulation and a possibility of retrograde filling into the upper brainstem through the fetal-variant PcoA. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Hong, J M, Choi, J Y, Lee, J H, Yong, S W, Bang, O Y, Joo, I S, Huh, K Tags: Stroke, Radiology, Radiology (diagnostics) Short reports Source Type: journals

Inherited Creutzfeldt-Jakob disease in a Dutch patient with a novel five octapeptide repeat insertion and unusual cerebellar morphologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
An atypical case of inherited Creutzfeldt–Jakob disease (CJD) is described in a 35-year-old Dutch woman, homozygous for methionine at codon 129 of the prion protein gene (PRNP). The clinical phenotype was characterised by slowly progressive cognitive decline and parkinsonism. Neuropathological findings consisted of scanty spongiosis and only faint to absent immunohistochemical staining for the abnormal prion protein, PrPSc, with patchy deposits in the cerebellar cortex. Purkinje cells were abnormally located in the molecular layer of the cerebellum. Western blot analysis showed the co-occurrence of PrPSc types 1 and ...
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Jansen, C, van Swieten, J C, Capellari, S, Strammiello, R, Parchi, P, Rozemuller, A J M Tags: Genetics, Immunology (including allergy), Brain stem / cerebellum, Memory disorders (neurology), Infection (neurology), Parkinson's disease, Neuropathology, Memory disorders (psychiatry) Short reports Source Type: journals

Prospective surveillance of drain associated meningitis/ventriculitis in a neurosurgery and neurological intensive care unitEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: To the best of the authors' knowledge, this study represents the first to provide data on EVD as well as LD associated meningitis rates calculated per 1000 DD; a parameter that is well established for other invasive devices such as central venous and urinary tract catheters. However, further prospective studies are needed to investigate the possible risk factors for meningitis. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Scheithauer, S, Burgel, U, Ryang, Y-M, Haase, G, Schiefer, J, Koch, S, Hafner, H, Lemmen, S Tags: Meningitis, Infection (neurology) Research papers Source Type: journals

A reappraisal of the value of lateral spread response monitoring in the treatment of hemifacial spasm by microvascular decompressionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Monitoring MVD by recording LSRs intraoperatively could be of value not only to indicate the resolution of the vasculonervous conflict at the end of surgery, but also to predict a successful clinical outcome in the long term after the surgical intervention. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Neves, D O, Lefaucheur, J-P, de Andrade, D C., Hattou, M, Ahdab, R, Ayache, S S, Le Guerinel, C, Keravel, Y Tags: Research papers Source Type: journals

The diagnostic value of provocative clinical tests in ulnar neuropathy at the elbow is marginalEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The diagnostic value of provocative clinical tests in UNE is poor. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Beekman, R, Schreuder, A H C M L, Rozeman, C A M, Koehler, P J, Uitdehaag, B M J Tags: Neuromuscular disease, Peripheral nerve disease Research papers Source Type: journals

Validity of diagnostic criteria for chronic inflammatory demyelinating polyneuropathy: a multicentre European studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: In our patient populations, the EFNS/PNS criteria were the most sensitive and allowed identification of a highly significantly greater number of patients than Koski et al’s criteria. The latter were comparable in specificity with the "definite/probable" EFNS/PNS electrodiagnostic subcategories. More extensive nerve-conduction studies improved diagnostic yield but resulted in loss of specificity. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Rajabally, Y A, Nicolas, G, Pieret, F, Bouche, P, Van den Bergh, P Y K Tags: Neuromuscular disease, Peripheral nerve disease Research papers Source Type: journals

Epidemiology and pathophysiology of falls in facioscapulohumeral diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: These findings demonstrate the high prevalence and clinical relevance of falls in FSHD. The relation between muscle weakness and instability among fallers is also highlighted. Because patients fell mainly at home, fall prevention strategies should focus on home adaptations. As mainly intrinsic causes underlie falls, the impact of adopting balance strategies or balance training should be explored in this patient group. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Horlings, C G C, Munneke, M, Bickerstaffe, A, Laverman, L, Allum, J H J, Padberg, G W A M, Bloem, B R, van Engelen, B G M Tags: Muscle disease, Neuromuscular disease, Musculoskeletal syndromes Research papers Source Type: journals

A case of stroke induced micrographiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Capone, F, Pilato, F, Profice, P, Pravata, E, Di Lazzaro, V Tags: Neuroimaging, Stroke, Hypertension Neurological pictures Source Type: journals

Assessment of spinal somatosensory systems with diffusion tensor imaging in syringomyeliaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The data indicate that diffusion tensor imaging with 3D-fibre tracking is a new imaging method suitable for the objective and quantitative anatomical assessment of spinal somatosensory system dysfunction. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Hatem, S M, Attal, N, Ducreux, D, Gautron, M, Parker, F, Plaghki, L, Bouhassira, D Tags: Spinal cord Research papers Source Type: journals

Proinflammatory cell stress in sporadic inclusion body myositis muscle: overexpression of {alpha}B-crystallin is associated with amyloid precursor protein and accumulation of {beta}-amyloidEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Our results suggest that B-crystallin is associated with overexpression of APP in sIBM muscle and that upregulation of B-crystallin precedes accumulation of β-amyloid. The data help to better understand early pathological changes and underscore the fact that a network of cell stress, inflammation and degeneration is relevant to sIBM. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Muth, I E, Barthel, K, Bahr, M, Dalakas, M C, Schmidt, J Tags: Immunology (including allergy), Muscle disease, Neuromuscular disease, Radiology, Musculoskeletal syndromes, Surgical diagnostic tests Research papers Source Type: journals

New acute and chronic black holes in patients with multiple sclerosis randomised to interferon beta-1b or glatiramer acetateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Background: Hypointense lesions on T1 weighted MRI, referred to as black holes (BH), are a marker of demyelination/axonal loss in multiple sclerosis (MS). There is some evidence that glatiramer acetate (GA) may decrease the conversion of new brain lesions to BH. Methods: Monthly 3-Tesla brain MRI scans were used for up to 2 years to study the development and evolution of new BH in 75 patients with MS randomised to GA or Interferon β-1b (IFNβ1b) in the BECOME study. Findings: Of 1224 newly enhancing lesions (NEL) appearing at baseline through 24 months in 61 patients, 767 (62.7%) showed an acute BH (ABH). The ma...
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Cadavid, D, Cheriyan, J, Skurnick, J, Lincoln, J A, Wolansky, L J, Cook, S D Tags: Immunology (including allergy), Multiple sclerosis, Neuroimaging, Radiology, Radiology (diagnostics) Research papers Source Type: journals

MR spectroscopy indicates diffuse multiple sclerosis activity during remissionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The absence of early tissue atrophy and apparent axonal dysfunction (NAA loss) in these RR MS patients suggests that both are preceded by diffuse glial proliferation (astrogliosis), as well as possible inflammation, demyelination and remyelination reflected by elevated mI, Cho and Cr, even during clinical remission and despite immunomodulatory treatment. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Kirov, I I, Patil, V, Babb, J S, Rusinek, H, Herbert, J, Gonen, O Tags: Immunology (including allergy), Multiple sclerosis Research papers Source Type: journals

Double depressor palsy caused by bilateral paramedian thalamic infarctsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Pal, S, Ferguson, E, Madill, S A, Salman, R A.-S. Tags: Cranial nerves, Drugs: CNS (not psychiatric), Neuroimaging, Sleep disorders (neurology), Stroke, Ophthalmology, Sleep disorders, Disability Neurological pictures Source Type: journals

Functional magnetic resonance imaging study on dysphagia after unilateral hemispheric stroke: a preliminary studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The results indicate that unilateral stroke of either cerebral hemisphere can produce dysphagia. Effective recovery is associated with cerebral activation related to cortical swallowing representation in the compensating or recruited areas of the intact hemisphere. Functional MRI is a useful method for exploring the spatial localisation of changes in neuronal activity during tasks that may be related to recovery. Therefore, the subsequent information gleaned from changes in neural plasticity could be useful for assessing the prognosis of dysphagic stroke. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Li, S, Luo, C, Yu, B, Yan, B, Gong, Q, He, C, He, L, Huang, X, Yao, D, Lui, S, Tang, H, Chen, Q, Zeng, Y, Zhou, D Tags: Stroke, Radiology, Radiology (diagnostics) Research papers Source Type: journals

Somatosensory temporal discrimination in patients with primary focal dystoniaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: These results provide definitive evidence that STDT abnormalities are a generalised feature of patients with primary focal dystonias and are a valid tool for screening subclinical sensory abnormalities. (Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Scontrini, A, Conte, A, Defazio, G, Fiorio, M, Fabbrini, G, Suppa, A, Tinazzi, M, Berardelli, A Tags: Movement disorders (other than Parkinsons) Research papers Source Type: journals

Diagnosis and new treatments in genetic neuropathiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The genetic neuropathies are a clinically and genetically heterogeneous group of diseases of which the most common types are Charcot–Marie–Tooth disease (CMT), the hereditary sensory and autonomic neuropathies and the distal hereditary motor neuropathies. More than 30 causative genes have been described, making an accurate genetic diagnosis increasingly possible. Although no specific therapies are yet available, research into their pathogenesis has revolutionised our understanding of the peripheral nervous system and allowed the development of rational approaches to therapy. The first therapeutic trials in CMT ...
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Reilly, M M, Shy, M E Tags: Genetics, Immunology (including allergy), Multiple sclerosis, Neuromuscular disease, Peripheral nerve disease Review Source Type: journals

Can mutations of prion protein shed light on its normal function?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Mallucci, G. R Tags: Immunology (including allergy), Brain stem / cerebellum, Infection (neurology), Neuropathology, Memory disorders (psychiatry) Editorial commentaries Source Type: journals

Drain associated meningitis and ventriculitis remains a pivotal problem in neurointensive care: to understand their causes we need better surveillance dataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Kasper, E. M. Tags: Meningitis, Infection (neurology) Editorial commentaries Source Type: journals

Sporadic inclusion body myositis: evidence of a link between inflammation, cell stress and {beta}-amyloid depositionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of Neurology, Neurosurgery & Psychiatry)
Source: Journal of Neurology, Neurosurgery & Psychiatry - November 16, 2009 Category: Neurosurgery Authors: Mastaglia, F. Tags: Immunology (including allergy), Muscle disease, Neuromuscular disease, Radiology, Drugs: musculoskeletal and joint diseases, Musculoskeletal syndromes, Surgical diagnostic tests Editorial commentaries Source Type: journals

Long-term results of thalamic deep brain stimulation for essential tremor.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Deep brain stimulation of the VIM is an efficient and safe treatment for ET. Tremor and handwriting improvements in long-term follow-up are stable. The patients' perception of their outcome is quite good. However, tolerance may develop in some patients requiring changes in stimulation parameters. PMID: 19911883 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Zhang K, Bhatia S, Oh MY, Cohen D, Angle C, Whiting D Tags: J Neurosurg Source Type: journals

Ventricular enlargement due to acute hypernatremia in a patient with a ventriculoperitoneal shunt.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Patients requiring CSF shunts frequently have comorbidities that can influence water and electrolyte balances. The authors report on a case involving a ventriculoperitoneal shunt in a patient who underwent intravenous hyperhydration and withdrawal of vasopressin substitution prior to scheduled high-dose chemotherapy regimen for a metastatic suprasellar germinoma. After acute neurological deterioration, the patient underwent CT scanning that demonstrated ventriculomegaly. A shunt tap revealed no flow and negative opening pressure. Due to suspicion of proximal shunt malfunction, the comatose patient underwent immediate s...
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Andres RH, Pendharkar AV, Kuhlen D, Mariani L Tags: J Neurosurg Source Type: journals

Atypical teratoid/rhabdoid tumor of the pineal region in an adult.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
An atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant embryonal tumor most often occurring in the posterior fossa in children younger than 3 years of age. Adult cases of AT/RT are very rare, and 27 cases with a diagnosis of either AT/RT or (malignant) rhabdoid tumor have been reported to date. The authors report an adult case of an AT/RT occurring in the pineal region with molecular cytogenetic and immunohistochemical confirmation. A 33-year-old woman presented with a 2-month history of headache and blurred vision progressing to diplopia, and was admitted emergently due to deteriorating mental status. An MR...
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Takei H, Adesina AM, Mehta V, Powell SZ, Langford LA Tags: J Neurosurg Source Type: journals

Hypomania with hypersexuality following bilateral anterior limb stimulation in obsessive-compulsive disorder.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This 28-year-old Chinese man was referred for deep brain stimulation (DBS) evaluation for an 8-year history of refractory obsessive-compulsive disorder. After the patient had signed an informed consent, the authors implanted DBS leads. Hypomania with hypersexuality was noted on stimulation at Contact 2 and became aggravated with a higher voltage (>/=3 V) during chronic bilateral DBS. After the voltage was decreased to 1 V, the patient's hypomanic symptoms subsided and his libido returned to baseline. PMID: 19911886 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Chang CH, Chen SY, Hsiao YL, Tsai ST, Tsai HC Tags: J Neurosurg Source Type: journals

Nationwide study of decompressive surgery for malignant supratentorial infarction in the Czech Republic: utilization and outcome predictors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In 2006 decompressive surgery was underutilized and occurred late in the clinical course in the Czech Republic. Revision of national guidelines is necessary to incorporate the latest data and ensure that the patients who can benefit most receive treatment. PMID: 19911887 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Bar M, Mikulik R, Skoloudík D, Czerny D, Lipina R, Klecka L, Juran V, Mraček J, Vondráčková D, Hrabalek L, Brzezny R, Dienelt J Tags: J Neurosurg Source Type: journals

Resection of malignant brain tumors in eloquent cortical areas: a new multimodal approach combining 5-aminolevulinic acid and intraoperative monitoring.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The authors' first results show that tumor resections with 5-ALA in combination with intraoperative cortical stimulation have the advantages of both methods and, thus, provide additional safety for the neurosurgeon during resections of primary malignant brain tumors in eloquent areas. Nonetheless, more cases and additional studies are necessary to further prove the advantages of this multimodal strategy. PMID: 19911888 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Feigl GC, Ritz R, Moraes M, Klein J, Ramina K, Gharabaghi A, Krischek B, Danz S, Bornemann A, Liebsch M, Tatagiba MS Tags: J Neurosurg Source Type: journals

Cerebrospinal fluid shunt insertion: techniques of peritoneal catheter placement separate from abdominal fascial and peritoneal incisions.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this report, the authors describe a simple technique for passing the peritoneal catheter of a ventriculoperitoneal shunt through the abdominal wall on a pathway separate from the fascial opening. This technique minimizes the risk of abdominal wall-related complications and is especially important in high-risk patients such as those with obesity and/or diabetes and in children. PMID: 19911889 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Elashaal AA, Corrin M, Cusimano MD Tags: J Neurosurg Source Type: journals

Intracellular free magnesium of brain and cerebral phosphorus-containing metabolites after subarachnoid hemorrhage and hypermagnesemic treatment: a (31)P-magnetic resonance spectroscopy study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The MRS finding of elevated brain free intracellular magnesium after intravenous magnesium sulfate infusion is novel, and the changes in membrane metabolism provide insight into the metabolic effects of aneurysmal SAH and future pathophysiological studies. PMID: 19911890 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Wong GK, Yeung DK, Ahuja AT, King AD, Lam CW, Chan MT, Gin T, Poon WS Tags: J Neurosurg Source Type: journals

Burst stimulation of the auditory cortex: a new form of neurostimulation for noise-like tinnitus suppression.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Burst stimulation is a new form of neurostimulation that might be helpful in treating symptoms that are intractable to conventional tonic stimulation. Further exploration of this new stimulation design is warranted. PMID: 19911891 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: De Ridder D, Vanneste S, van der Loo E, Plazier M, Menovsky T, van de Heyning P Tags: J Neurosurg Source Type: journals

Age- and time-dependent effects on functional outcome and cortical activation pattern in patients with median nerve injury: a functional magnetic resonance imaging study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Following a median nerve injury (1-11 years after injury) there may be an initial increase in the volume of the cortical representation, which subsequently declines during the restoration phase. These dynamic changes may involve both median and ulnar nerve cortical representation, because both showed negative correlation with time after injury. These findings are in agreement with animal studies showing that cortical plasticity is an important mechanism for functional recovery after peripheral nerve injury and repair. PMID: 19911892 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Fornander L, Nyman T, Hansson T, Ragnehed M, Brismar T Tags: J Neurosurg Source Type: journals

Cellular transplantation for the nervous system: impact of time after preparation on cell viability and survival.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The authors' results indicate that that there can be significant losses in viability between preparation and implantation and that more sophisticated methods of evaluation, such as the ability of cells to attach to a substrate and grow, may be required to detect decreases in viability. The time between preparation and implantation will be an important factor in clinical trial design. PMID: 19911893 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Gobbel GT, Kondziolka D, Fellows-Mayle W, Uram M Tags: J Neurosurg Source Type: journals

Continuous hypertension and tachycardia after resection of a hemangioblastoma behind the dorsal medulla oblongata: relationship to sympathetic overactivity at the neurogenic vasomotor center.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A very rare case of continuous hypertension and tachycardia after excision of a cerebellar hemangioblastoma at the dorsal medulla oblongata is presented. This 21-year-old man was admitted to the authors' hospital with a headache and dizziness. Radiological examination revealed a tumor located behind the dorsal medulla oblongata and compressing it substantially. The tumor was completely resected, but after the surgery the patient experienced prolonged hypertension and tachycardia. Postoperative MR imaging showed a small injury at the dorsocaudal medulla that was located at the caudal site of the nucleus of the tractus s...
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Ideguchi M, Kajiwara K, Yoshikawa K, Kato S, Ishihara H, Fujii M, Fujisawa H, Suzuki M Tags: J Neurosurg Source Type: journals

Effectiveness of an epidural blood patch for patients with intracranial hypotension syndrome and persistent spinal epidural fluid collection after treatment.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions An epidural blood patch is effective for sealing of CSF leaks, but the resolution of SIHS-related symptoms does not always imply complete eradication of the leakage. PMID: 19911895 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2009 Category: Neurosurgery Authors: Horikoshi T, Watanabe A, Uchida M, Kinouchi H Tags: J Neurosurg Source Type: journals

ErratumEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Zentralbl NeurochirDOI: 10.1055/s-0029-1243182© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | FREE: Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - November 12, 2009 Category: Neurosurgery Tags: Erratum Source Type: journals