Neurosurgery 
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41914 records returned
Beta Amyloid Alters Cognition Even in Healthy AdultsBeta Amyloid Alters Cognition Even in Healthy Adults
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About 20% of participants older than 60 years in a new study had amyloid accumulations. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 6, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Pain Negatively Affects Cognition in FibromyalgiaPain Negatively Affects Cognition in FibromyalgiaEmail this article to a colleague.
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Pain decreased mathematical abilities and attention control more than depression, anxiety, fatigue, sleep complaints, or medication use. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 6, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Spinal Cord Stimulation Effective for HIV NeuropathySpinal Cord Stimulation Effective for HIV NeuropathyEmail this article to a colleague.
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This approach should be "a first-line therapy once individuals are identified with this peripheral neuropathic pain process," says researcher. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 6, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
WHO Grade III Anaplastic Meningioma Metastasizing to the Parotid Gland and the Lungs: Case Report and Review of the LiteratureEmail this article to a colleague.
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Cen Eur NeurosurgDOI: 10.1055/s-0032-1304564[...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | FREE Full text (Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery)
Source: Zentralblatt fur Neurochirurgie - Central European Neurosurgery - February 6, 2012 Category: Neurosurgery Authors: Herbst, A.Mueller-Vogt, U.Brawanski, A.Proescholdt, M.Riemenschneider, M. J.Schebesch, K.-M. Tags: Erratum Source Type: research
An intraoperative multimodal neurophysiologic approach to successful resection of precentral gyrus epileptogenic lesionsEmail this article to a colleague.
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We present an illustrative case of intractable epilepsy where judicious use of intraoperative neurophysiologic–techniques guided resection of precentral CD, under general anesthesia and in the absence of preoperative electrophysiologic mapping data. Ictal onset was accurately delineated using electrocorticography (ECoG). Phase reversal of the median somatosensory‐evoked potentials (MSSEPs) localized the central sulcus (CS). Motor evoked potentials (MEPs) triggered by high‐frequency monopolar anodal electrical cortical stimulation at the primary motor cortex (PMC) threshold delineated the PMC. Using this technique, PM...
Source: Epilepsia - February 6, 2012 Category: Neurology Authors: Mirela V. SimonAndrew J. ColeEric C. ChangBradley R. BuchbinderSteve M. StufflebeamAla NozariAnat O. Stemmer‐RachamimovEmad N. Eskandar Tags: BRIEF COMMUNICATION Source Type: research
A Patient With ALS and Atypical Clinical FeaturesA Patient With ALS and Atypical Clinical FeaturesEmail this article to a colleague.
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The presentation of amyotrophic lateral sclerosis can be variable, and proper diagnosis is essential for prognosis and management. In this case, symptoms were atypical, and diagnosis came too late. Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 5, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news
Solitaire Clot Retrieval Device Outperforms Merci in StrokeSolitaire Clot Retrieval Device Outperforms Merci in StrokeEmail this article to a colleague.
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The study was halted early because of numerous significant improvements with the Solitaire device. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 5, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
What Are the Major Diseases Involving Copper Metabolism?Email this article to a colleague.
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Discussion
Nutritional problems can occur in all parts of the world and in all socioeconomic strata. Caloric and/or protein inadequacy unfortunately plagues too many people because of inadequate supplies or availability. Supplemental food programs around the world attempt to provide appropriate nutrition, but can be stymied because of war, political instability, economic instability and many other social factors.
The most common specific nutrient deficiencies are iron and Vitamin D deficiencies. Minerals important for essential nutrition include copper, iodine, selenium and zinc. A typical mixed diet usually provides enou...
Source: PediatricEducation.org - February 5, 2012 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news
WSSF Society NewsEmail this article to a colleague.
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Stereotact Funct Neurosurg 2012;90:66 (DOI:10.1159/000336392) (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 5, 2012 Category: Neurosurgery Source Type: research
ASSFN Society NewsEmail this article to a colleague.
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Stereotact Funct Neurosurg 2012;90:67 (DOI:10.1159/000336394) (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 5, 2012 Category: Neurosurgery Source Type: research
ESSFN MissionEmail this article to a colleague.
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Stereotact Funct Neurosurg 2012;90:68 (DOI:10.1159/000336396) (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 5, 2012 Category: Neurosurgery Source Type: research
Front & Back MatterEmail this article to a colleague.
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Stereotact Funct Neurosurg 2012;90:X (DOI:10.1159/000337008) (Source: Stereotactic and Functional Neurosurgery)
Source: Stereotactic and Functional Neurosurgery - February 5, 2012 Category: Neurosurgery Source Type: research
Treating Brain Injuries With Stem Cell Transplants - Promising ResultsEmail this article to a colleague.
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The February edition of Neurosurgery reports that animal experiments in brain-injured rats have shown that stem cells injected via the carotid artery travel directly to the brain, greatly enhancing functional recovery... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 4, 2012 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news
Study Looks At Reasons For Lack Of Improvement In Outcomes For Treatment Of Unruptured Brain AneurysmsEmail this article to a colleague.
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Despite advances in the diagnosis and treatment of unruptured brain aneurysms, outcomes have remained stagnant over the last 10 years. This can be explained by the dramatic proliferation of minimally invasive endoscopic coiling procedures at lower-volume community hospitals, where outcomes are inferior. These findings are reported in a study by neurologists, neurosurgeons and neuro-anesthesiologists at NewYork-Presbyterian Hospital/Columbia University Medical Center and published in the journal Stroke... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 4, 2012 Category: Consumer Health News Tags: Stroke Source Type: news
Brain Blood Flow And Oxygen Monitored By First-Of-Its-Kind Head PatchEmail this article to a colleague.
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A research team led by investigators at Mayo Clinic in Florida has found that a small device worn on a patient's brow can be useful in monitoring stroke patients in the hospital. The device measures blood oxygen, similar to a pulse oximeter, which is clipped onto a finger. Their study, published in Neurosurgical Focus, suggests this tool, known as frontal near-infrared spectroscopy (NIRS), could offer hospital physicians a safe and cost-effective way to monitor patients who are being treated for a stroke, in real time... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 4, 2012 Category: Consumer Health News Tags: Stroke Source Type: news
Aspirin as Effective as Warfarin in Heart Failure: WARCEFAspirin as Effective as Warfarin in Heart Failure: WARCEFEmail this article to a colleague.
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Although there was an edge for warfarin for those treated for 4 or more years, there is "no compelling" reason to anticoagulate these patients, researchers say. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 3, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
No Stroke Prevention Benefit of Clopidogrel Plus AspirinNo Stroke Prevention Benefit of Clopidogrel Plus AspirinEmail this article to a colleague.
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A new study shows that the combination clopidogrel and aspirin increases risk of hemorrhage and mortality including non-vascular mortality vs aspirin alone. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 3, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Continuous Near-Infrared Regional Cerebral Perfusion Monitoring Shows Promise in Stroke PatientsEmail this article to a colleague.
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Researchers at Mayo Clinic in Florida have shown that cerebral optically-based near infra-red spectroscopic oximetry applied to patients who have suffered a stroke can help monitor regional cerebral perfusion in real time, and thus “may serve as a useful, noninvasive, bedside intensive care unit monitoring tool to assess brain oxygenation in a direct manner.” The study looked at the device called Fore-Sight from Casmed of Branford, CT, that measures blood oxygen, similar to a finger clip pulse oximeter. The Mayo study results have been published in Journal of Neurosurgery this month.Regional cerebral blood flo...
Source: Medgadget Anesthesiology - February 3, 2012 Category: Anesthesiology Authors: Jan Sinnige Tags: Anesthesiology Cardiac Surgery Critical Care Neurological Surgery Neurology Source Type: news
Single low dose adjuvant Gamma knife radiosurgery for Thyrotropin secreting pituitary adenomaEmail this article to a colleague.
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Content Type Journal ArticleCategory Letter to the editorPages 1-2DOI 10.1007/s00701-012-1284-6Authors
Manish K. Kasliwal, Department of Neurosurgery and Gamma Knife Neurosciences Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India 110029Aditya Gupta, Department of Neurosurgery and Gamma Knife Neurosciences Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India 110029Manish S. Sharma, Department of Neurosurgery and Gamma Knife Neurosciences Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India 110029
Journal Acta NeurochirurgicaOnline...
Source: Acta Neurochirurgica - February 3, 2012 Category: Neurology Tags: Acta Neurochirurgica Source Type: research
Types and severity of operated supraclavicular brachial plexus injuries caused by traffic accidentsEmail this article to a colleague.
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Conclusion Study results indicate that the most common injury was an upper plexus palsy. It was characteristic of bicycle accidents,
and significantly more common in car and motorcycle accidents. The results also indicate that it is important to consider
the potential of a brachial plexus injury after serious traffic accidents and to examine both upper extremities in detail
even if some motor function is preserved.
Content Type Journal ArticleCategory Clinical ArticlePages 1-5DOI 10.1007/s00701-012-1291-7Authors
Radek Kaiser, Third Faculty of Medicine, Department of Neurosurgery, Hospital Kralovske...
Source: Acta Neurochirurgica - February 3, 2012 Category: Neurology Tags: Acta Neurochirurgica Source Type: research
Brain Tissue Oxygenation and Cerebral Perfusion Pressure Thresholds of Ischemia in a Standardized Pig Brain Death ModelEmail this article to a colleague.
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Conclusions A severe increase of ICP leading to CPP below 30 mmHg and BtipO2 below 10 mmHg is associated with an increase of the L/P ratio, thus seems to be critical thresholds for cerebral ischemia
under these conditions.
Content Type Journal ArticleCategory Translational ResearchPages 1-8DOI 10.1007/s12028-012-9675-3Authors
Karlis Purins, Department of Neuroscience, Section of Neurosurgery, Uppsala University, 751 85 Uppsala, SwedenPer Enblad, Department of Neuroscience, Section of Neurosurgery, Uppsala University, 751 85 Uppsala, SwedenLars Wiklund, Department of Surgical Sciences, Secti...
Source: Neurocritical Care - February 3, 2012 Category: Neurology Tags: Neurocritical Care Source Type: research
Rapid Assessment of Sleep-Wake Behavior in MiceEmail this article to a colleague.
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Sleep is a fundamental biological rhythm involving the interaction of numerous brain structures and diverse neurotransmitter systems. The primary measures used to define sleep are the electroencephalogram (EEG) and electromyogram (EMG). However, EEG-based methods are often unsuitable for use in high-throughput screens as they are time-intensive and involve invasive surgery. As such, the dissection of sleep mechanisms and the discovery of novel drugs that modulate sleep would benefit greatly from further development of rapid behavioral assays to assess sleep in animal models. Here is described an automated noninvasive appro...
Source: Journal of Biological Rhythms - February 3, 2012 Category: Research Authors: Fisher, S. P., Godinho, S. I. H., Pothecary, C. A., Hankins, M. W., Foster, R. G., Peirson, S. N. Tags: Articles Source Type: research
Dexpramipexole in ALS: Cautious OptimismDexpramipexole in ALS: Cautious OptimismEmail this article to a colleague.
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Might the experimental drug dexpramipexole slow disease progression in ALS? Results of a Phase II trial are promising. Journal Watch (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 2, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news
Cardiac Telemetry Identifies Atrial Fibrillation in Cryptogenic Stroke Cardiac Telemetry Identifies Atrial Fibrillation in Cryptogenic StrokeEmail this article to a colleague.
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Outpatient monitoring for 21 days detected atrial fibrillation in 17% of patients, and this could change management. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 2, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Prognostic Significance of Angiogenesis in Relation to Ki-67, p-53, p-27, and bcl-2 Expression in Embryonal TumorsEmail this article to a colleague.
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Pediatr Neurosurg (DOI:10.1159/000335398) (Source: Pediatric Neurosurgery)
Source: Pediatric Neurosurgery - February 2, 2012 Category: Neurosurgery Source Type: research
Improved Outcomes in Acute Stroke: An Effective ProtocolImproved Outcomes in Acute Stroke: An Effective ProtocolEmail this article to a colleague.
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Dr. Hans-Cristoph Diener looks at the impact of evidence-based management protocols in fever, hyperglycemia, and swallowing dysfunction associated with acute stroke. Medscape Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 2, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery Commentary Source Type: news
Severe Anemia Potent Predictor of Death After StrokeSevere Anemia Potent Predictor of Death After StrokeEmail this article to a colleague.
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Study results should prompt physicians to take a closer look at what’s causing anemia in stroke patients. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 2, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
High Rate of Sleep Apnea in Patients With Silent StrokesHigh Rate of Sleep Apnea in Patients With Silent StrokesEmail this article to a colleague.
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A new study finds half of patients with clinically silent stroke and a third of those with microvascular changes have sleep apnea. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 2, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Cardinal Health Releases Smart-Seal Surgical MaskEmail this article to a colleague.
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Cardinal Health has made available its Smart-Seal surgical mask that improves both its fit and reduces interior fogging while providing a high level of filtration and resistance to liquids.From the announcement:Read More (Source: Medgadget Anesthesiology)
Source: Medgadget Anesthesiology - February 2, 2012 Category: Anesthesiology Authors: Gene Ostrovsky Tags: Anesthesiology Cardiac Surgery Emergency Medicine Neurological Surgery Ob/Gyn Orthopedic Surgery Plastic Surgery Thoracic Surgery Urology Source Type: news
An essential role for p38 MAPK in cerebellar granule neuron precursor proliferationEmail this article to a colleague.
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Abstract Development of the cerebellum occurs postnatally and is marked by a rapid proliferation of cerebellar granule neuron precursors
(CGNPs). CGNPs are the cells of origin for SHH-driven medulloblastoma, the most common malignant brain tumor in children.
Here, we investigated the role of ERK, JNK, and p38 mitogen-activated protein kinases in CGNP proliferation. We found high
levels of p38α in proliferating CGNPs. Concomitantly, members of the p38 pathway, such as ASK1, MKK3 and ATF-2, were also
elevated. Inhibition of the Shh pathway or CGNP proliferation blunts p38α levels, irrespective of Shh treatme...
Source: Acta Neuropathologica - February 2, 2012 Category: Neurology Tags: Acta Neuropathologica Source Type: research
Computer-aided volumetric analysis as a sensitive tool for the management of incidental meningiomasEmail this article to a colleague.
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Conclusion Overall, we found that computer-aided perimeter methods showed a more accurate picture of tumor progression than traditional
methods, which generally underestimated growth.
Content Type Journal ArticleCategory Clinical ArticlePages 1-9DOI 10.1007/s00701-012-1273-9Authors
Victor Chang, Department of Neurosurgery, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USAJayang Narang, Department of Radiology Neuroscience Institute, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USALonni Schultz, Department of Biostatistics and Research Epidemiology, Henry Ford Heal...
Source: Acta Neurochirurgica - February 2, 2012 Category: Neurology Tags: Acta Neurochirurgica Source Type: research
Frequency of mutations in the genes associated with hereditary sensory and autonomic neuropathy in a UK cohortEmail this article to a colleague.
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Abstract The hereditary sensory and autonomic neuropathies (HSAN, also known as the hereditary sensory neuropathies) are a clinically
and genetically heterogeneous group of disorders, characterised by a progressive sensory neuropathy often complicated by ulcers
and amputations, with variable motor and autonomic involvement. To date, mutations in twelve genes have been identified as
causing HSAN. To study the frequency of mutations in these genes and the associated phenotypes, we screened 140 index patients
in our inherited neuropathy cohort with a clinical diagnosis of HSAN for mutations in the coding region...
Source: Journal of Neurology - February 2, 2012 Category: Neurology Tags: Journal of Neurology Source Type: research
Acute Treatment Options for Spinal Cord InjuryEmail this article to a colleague.
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Opinion statement Most treatment options for acute traumatic spinal cord injury (SCI) are directed at minimizing progression of the initial
injury and preventing secondary injury. Failure to adhere to certain guiding principles can be detrimental to the long-term
neurologic and functional outcome of these patients. Therapy for the hyperacute phase of traumatic SCI focuses on stabilizing
vital signs and follows the Advanced Trauma Life Support (ATLS) algorithm for ensuring stability of airway, breathing and
circulation, and disability (neurologic evaluation)—with spinal stabilization—and exposure. Spinal ...
Source: Current Treatment Options in Neurology - February 2, 2012 Category: Neurology Tags: Current Treatment Options in Neurology Source Type: research
Relationship between kidney damage and stroke types in Japanese patientsEmail this article to a colleague.
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Conclusions This study shows that kidney damage is common in Japanese stroke patients, and proteinuria and renal insufficiency are differentially
related to development and prognosis, depending stroke types.
Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s10157-012-0594-6Authors
Kosuke Kudo, Department of Nephrology, Yamagata City Hospital Saiseikan, Yamagata, JapanTsuneo Konta, Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata, 990-9585 JapanNoriyuki Degawa, Department of Nephrology, Yamagata City Hosp...
Source: Clinical and Experimental Nephrology - February 2, 2012 Category: Urology & Nephrology Tags: Clinical and Experimental Nephrology Source Type: research
A meningioma with peripheral rim enhancement on MRIEmail this article to a colleague.
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Abstract Meningiomas are common, typically benign intracranial neoplasms with well-demarcated borders. Meningiomas with indistinct
boundaries have been reported. These can invade surrounding structures, and present surgical and diagnostic challenges. We
present the case of an unusual meningioma in a 53-year-old male in which preoperative magnetic resonance imaging (MRI) revealed
an irregular lesion with clear boundaries and peripheral rim enhancement. Intraoperatively, however, no cleavage plane was
apparent. Histological examination showed an increase of fibroconnective tissue with proliferation of dilated ...
Source: Brain Tumor Pathology - February 2, 2012 Category: Neurology Tags: Brain Tumor Pathology Source Type: research
Deep-Brain Stimulation in Parkinson Disease: 10-Year OutcomesDeep-Brain Stimulation in Parkinson Disease: 10-Year OutcomesEmail this article to a colleague.
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A blinded study seeks to determine whether the benefits of deep-brain stimulation in Parkinson disease are sustained over the long term. Medscape Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 2, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery Viewpoint Source Type: news
Severe, Rapid Memory Loss Could Herald StrokeSevere, Rapid Memory Loss Could Herald StrokeEmail this article to a colleague.
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A new study finds that fatal stroke victims had sharp memory declines before event. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 2, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Anterolateral Mini Fronto-Orbito-Zygomatic Craniotomy via an Eyebrow Incision in Pediatrics: Technical Notes and EvaluationEmail this article to a colleague.
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Pediatr Neurosurg (DOI:10.1159/000335399) (Source: Karger Publishers)
Source: Karger Publishers - February 2, 2012 Category: Cancer & Oncology Source Type: research
Protective Effects of Edaravone on Experimental Spinal Cord Injury in RatsEmail this article to a colleague.
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Pediatr Neurosurg (DOI:10.1159/000335400) (Source: Karger Publishers)
Source: Karger Publishers - February 2, 2012 Category: Cancer & Oncology Source Type: research
Surveillance Study of Healthcare-Associated Infections in a Pediatric Neurosurgery Unit in ItalyEmail this article to a colleague.
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Pediatr Neurosurg (DOI:10.1159/000335401) (Source: Karger Publishers)
Source: Karger Publishers - February 2, 2012 Category: Cancer & Oncology Source Type: research
Recombinant Human Bone Morphogenetic Protein-2 as an Adjunct for Spine Fusion in a Pediatric PopulationEmail this article to a colleague.
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Pediatr Neurosurg (DOI:10.1159/000335424) (Source: Karger Publishers)
Source: Karger Publishers - February 2, 2012 Category: Cancer & Oncology Source Type: research
Retroclival Epidural Hematoma in a Child Affected by Whiplash Cervical Injury: A Typical Case of a Rare ConditionEmail this article to a colleague.
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Pediatr Neurosurg (DOI:10.1159/000335446) (Source: Karger Publishers)
Source: Karger Publishers - February 2, 2012 Category: Cancer & Oncology Source Type: research
Chiari III MalformationEmail this article to a colleague.
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Pediatr Neurosurg (DOI:10.1159/000335651) (Source: Karger Publishers)
Source: Karger Publishers - February 2, 2012 Category: Cancer & Oncology Source Type: research
The relation between zoledronic acid infusion and interbody fusion in patients undergoing transforaminal lumbar interbody fusion surgeryEmail this article to a colleague.
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Conclusions There was no association between ZOL treatment and nonunion of the lumbar spinal bone. Thus, undergoing lumbar interbody fusion
surgery is not a valid reason to suspend or avoid treatment with ZOL.
Content Type Journal ArticleCategory Clinical ArticlePages 1-8DOI 10.1007/s00701-012-1283-7Authors
Chao Li, Department of Orthopedics, Zhongshan Hospital, Fudan University, Shanghai, ChinaHui-Ren Wang, Department of Orthopedics, Zhongshan Hospital, Fudan University, Shanghai, ChinaXi-Lei Li, Department of Orthopedics, Zhongshan Hospital, Fudan University, Shanghai, ChinaXiao-Gang Zhou, Departme...
Source: Acta Neurochirurgica - February 2, 2012 Category: Neurology Tags: Acta Neurochirurgica Source Type: research
GM-CSF protects rat photoreceptors from death by activating the SRC-dependent signalling and elevating anti-apoptotic factors and neurotrophinsEmail this article to a colleague.
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Conclusions The data suggest that GM-CSF is a potent therapeutic agent in photoreceptor degeneration caused by mutation of the receptor
tyrosine kinase gene (Mertk), and may be also effective in other photoreceptor degeneration.
Content Type Journal ArticleCategory Basic SciencePages 1-14DOI 10.1007/s00417-012-1932-9Authors
Maurice Schallenberg, Department of Experimental Ophthalmology, School of Medicine, University Eye Hospital Münster and Interdisciplinary Centre for Clinical Research (IZKF), Domagkstrasse 15, 48149 Münster, GermanyPetar Charalambous, Department of Experimental Ophthalmology, Sc...
Source: Graefe's Archive for Clinical and Experimental Ophthalmology - February 2, 2012 Category: Opthalmology Tags: Graefe's Archive for Clinical and Experimental Ophthalmology Source Type: research
Genetic screening of Greek patients with Huntington's disease phenocopies identifies an SCA8 expansionEmail this article to a colleague.
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In this study we screened a cohort of 21 Greek patients with
HD phenocopy syndromes for mutations causing HDL2, SCA17, SCA1, SCA2, SCA3, SCA8, SCA12 and DRPLA. Fifteen patients (71%)
had a positive family history. We identified one patient (4.8% of the total cohort) with an expansion of 81 combined CTA/CTG
repeats at the SCA8 locus. This falls within what is believed to be the high-penetrance allele range. In addition to the classic
HD triad, the patient had features of dystonia and oculomotor apraxia. There were no cases of HDL2, SCA17, SCA1, SCA2, SCA3,
SCA12 or DRPLA. Given the controversy surrounding the SCA8 expa...
Source: Journal of Neurology - February 2, 2012 Category: Neurology Tags: Journal of Neurology Source Type: research
Visualization versus Neuromonitoring of Recurrent Laryngeal Nerves during Thyroidectomy: What About the Costs?Email this article to a colleague.
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Conclusions The regional DRG tariff for thyroid surgery is barely sufficient to cover conventional surgery costs. Intraoperative neural
monitoring accounts for 5–7% of the hospitalization costs for a thyroidectomy.
Content Type Journal ArticlePages 1-7DOI 10.1007/s00268-012-1452-0Authors
Gianlorenzo Dionigi, Department of Surgical Sciences, Endocrine Surgery Research Center, University of Insubria Varese-Como, Via Guicciardini, 21100 Varese, ItalyAlessandro Bacuzzi, Department of Anesthesia, University of Insubria, 21100 Varese, ItalyLuigi Boni, Department of Surgical Sciences, Endocrine Surgery Re...
Source: World Journal of Surgery - February 2, 2012 Category: Surgery Tags: World Journal of Surgery Source Type: research
Clazosentan Reduces Vasospasm After Subarachnoid HemorrhageClazosentan Reduces Vasospasm After Subarachnoid HemorrhageEmail this article to a colleague.
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However, clinical outcomes, including neurological deficits, were not improved. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 1, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Neurologists Weigh in on Tourette's-Like 'Mystery Illness'Neurologists Weigh in on Tourette's-Like 'Mystery Illness'Email this article to a colleague.
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Experts say conversion disorder explains the symptoms experienced by a cluster of girls at a New York school, but environmentalists question chemical spill. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 1, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Restenosis Similar With Carotid Stenting or Surgery: CRESTRestenosis Similar With Carotid Stenting or Surgery: CRESTEmail this article to a colleague.
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At 2 years, carotid restenosis is infrequent and appears similar whether patients were treated with carotid stenting or endarterectomy. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 1, 2012 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
