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This page shows you the most recent publications within this specialty of the MedWorm directory.

Nutritional status and nutrition risk screening in hospitalized children in New Zealand
ConclusionHospitalized children have higher rates of under‐nutrition than healthy children in NZ. The three NRS tools were able to identify children at nutritional risk with differing utility. In this setting, STRONGkids was the most reliable tool.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - May 23, 2013 Category: Pediatrics Authors: Vesal Moeeni, Tony Walls, Andrew S Day Tags: Regular Article Source Type: research

Outcomes of a mentored research competition for authoring pediatric case reports in chiropractic.
CONCLUSION: The project ultimately fulfilled the goal of using a mentorship model to facilitate scientific writing education and ease the anxiety of authoring a first publication. The overall experience was "good"; however, there are opportunities for improvement. PMID: 23519131 [PubMed] (Source: The Journal of Chiropractic Education)
Source: The Journal of Chiropractic Education - May 23, 2013 Category: Podiatry Authors: Pohlman KA, Vallone S, Nightingale LM Tags: J Chiropr Educ Source Type: research

Medical progress, psychological factors and global care of the patient: lessons from the treatment of childhood leukemia.
Abstract The history of treatment of childhood leukemia is a meaningful model of ethical, bioethical and organizational repercussions of medical progress. Specifically, it has provided precious indications and very useful tools to cope with several of the more important problems of modern medicine: the value of controlled randomized studies; the risks of intense medicalization impairing the quality of care; the importance of a valid doctor-patient relationship; the psycho-emotive involvement of the pediatric staff; and last but not least, the need of an unrelenting effort of humanization of the procedures and envir...
Source: Ann Ist Super Sanita - May 22, 2013 Category: Biomedical Science Authors: Digilio G, Digilio M Tags: Ann Ist Super Sanita Source Type: research

Potential Advantages of Using Synchrotron X-ray Based Techniques in Pediatric Research.
Abstract Synchrotron radiation (SR), which combines extremely high intensity, high collimation, tunability, and continuous energy spectrum, allows the development of advanced X-ray based techniques that are becoming a uniquely useful tool in life science research, along providing exciting opportunities in biomedical imaging and radiotherapy. This review summarize emerging techniques and their potential to greatly enhance the exploration of dynamical biological process occurring across various spatial and temporal regimes, from whole body physiology, down to the location of individual chemical species within single ...
Source: Current Medicinal Chemistry - May 22, 2013 Category: Chemistry Authors: Pascolo L, Esteve F, Rizzardi C, James S, Menk RH Tags: Curr Med Chem Source Type: research

MDM2 Non-Genotoxic Inhibitors as Innovative Therapeutic Approaches for the Treatment of Pediatric Malignancies.
Abstract Since the discovery of p53 as "guardian of the genome" , a large number of efforts have been put in place in order to find molecular strategies aiming to restore p53 wild-type functions, particularly in the light of the fact that its pathway results ineffective in most tumors even though they have non-mutated p53. In this context, pediatric cancers, that are mostly p53 wild-type at the time of diagnosis, represent an ideal target for such therapeutic approach. Within the several mechanisms and proteins ruling p53 activity, the murine double minute 2 (MDM2) is its crucial negative regulator, frequently foun...
Source: Current Medicinal Chemistry - May 22, 2013 Category: Chemistry Authors: Tisato V, Norcio A, Voltan R, Celeghini C, Zella D, Secchiero P Tags: Curr Med Chem Source Type: research

TRAIL-Based Therapeutic Approaches for the Treatment of Pediatric Malignancies.
We describe the extrinsic and intrinsic pro-apoptotic pathways of TRAIL, together with the evidences for its pro-survival signaling, and with the relevance of these pathways in therapy. Possible mechanisms of resistance to TRAIL-induced apoptosis are highlighted (i.e. c-FLIP, Bcl-2, IAPs, p53, NF-κ B) and the rationale for the combined administration of TRAIL with drugs targeting these mechanisms is provided. Preclinical data are reported and show encouraging evidences for TRAIL consideration in pediatric malignancies (i.e., leukemia, lymphomas, neuroblastoma, osteosarcoma, medulloblastoma). Clinical trials of TRAIL-based...
Source: Current Medicinal Chemistry - May 22, 2013 Category: Chemistry Authors: Gasparini C, Brumatti LV, Monasta L, Zauli G Tags: Curr Med Chem Source Type: research

Perspectives offered by single-domain antibodies in clinical diagnostic of pediatric tumors.
Abstract The results accrued in the last few years have clearly showed that recombinant antibodies, and specifically single- domain antibodies, represent valid alternatives to conventional IgGs for in vivo imaging. It does not simply mean that antibody fragments can substitute full-length antibodies, but that they are substantially more suitable for some applications and can perform other functions for which no real alternative is available. Brain imaging with multi-functional probes is an evident example, but the promising results obtained with micro-PET and -SPECT in murine models could lead in short time to a re...
Source: Current Medicinal Chemistry - May 22, 2013 Category: Chemistry Authors: de Marco A Tags: Curr Med Chem Source Type: research

Raman spectroscopy and imaging: promising optical diagnostic tools in pediatrics.
Abstract This review focuses on the use of Raman spectroscopy, an analytical technique based on the inelastic scattering of harmless laser light with biological tissues, as an innovative diagnostic tool in pediatrics. After a brief introduction to explain the fundamental concepts behind Raman spectroscopy and imaging, a short summary is given of the most important and common issues arising when handling spectral data with multivariate statistics. Then, the most relevant papers in which Raman spectroscopy or imaging has been applied with diagnostic purposes to pediatric patients are reviewed, and grouped according t...
Source: Current Medicinal Chemistry - May 22, 2013 Category: Chemistry Authors: Beleites C, Bonifacio A, Codrich D, Krafft C, Sergo V Tags: Curr Med Chem Source Type: research

Editorial (hot topic: innovative approaches for the management of pediatric malignancies).
PMID: 23458622 [PubMed - in process] (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - May 22, 2013 Category: Chemistry Authors: Zauli G Tags: Curr Med Chem Source Type: research

Prevalence of contact allergy in children suffering from atopic dermatitis, seborrhoeic dermatitis and in healthy controls.
CONCLUSIONS: The statistically significant positive results in the highest proportion of patch tests in the youngest age subpopulation of children with atopic dermatitis, and detection of contact allergy most commonly in the youngest subgroup of healthy children, may suggest nonspecifically positive results associated with the immaturity of the epidermal barrier during the first years of life. Concentrations of contact allergens included in current pediatric sets of patch tests seems to be too high and should be verified. PMID: 23540212 [PubMed - in process] (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - May 22, 2013 Category: Environmental Health Authors: Silny W, Bartoszak L, Jenerowicz D, Żukiewicz-Sobczak W, Goździewska M Tags: Ann Agric Environ Med Source Type: research

A simulation study of spine biofidelity in the hybrid-III 6-year-old ATD.
CONCLUSIONS: Future ATD spine modification should focus on reducing the neck and lumbar tension stiffness and adding additional flexibility both in flexion/extension and tension at the thoracic spine region. The child ATD model developed in this study can be used as an important tool to improve child ATD biofidelity and child restraint system design in motor vehicle crashes. PMID: 23531263 [PubMed - in process] (Source: Traffic Injury Prevention)
Source: Traffic Injury Prevention - May 22, 2013 Category: Occupational Health Authors: Wu J, Cao L, Reed MP, Hu J Tags: Traffic Inj Prev Source Type: research

Severe Left Main Coronary Artery Stenosis with Abnormal Branching Pattern in a Patient with Mild Supravalvar Aortic Stenosis and Williams‐Beuren Syndrome
Abstract Williams–Beuren syndrome (WBS) is a multisystem genetic disorder comprising of craniofacial, developmental, and cardiac malformations. The most common cardiac defects found are supravalvar aortic stenosis and peripheral pulmonary stenosis. However, WBS should be regarded as a general arteriopathy consisting of stenoses of medium‐ and large‐sized arteries including the coronary arteries. Cardiac manifestations are often the initial reason for referral and careful cardiovascular assessment is important as coronary artery involvement confers a significant anesthetic risk and may be associated with ischemia and ...
Source: Congenital Heart Disease - May 22, 2013 Category: Cardiology Authors: Guido E. Pieles, Victor Ofoe, Gareth J. Morgan Tags: Case Report Source Type: research

Integrating a sense of coherence into the neonatal environment
DiscussionIn this paper we present a new perspective to neonatal care based on Aaron Antonovksy's Sense of Coherence (SOC) theory of well-being and positive health. Whilst the SOC was originally conceptualised as a psychological-based construct, the SOC's three underpinning concepts of comprehensibility, manageability and meaningfulness provide a theoretical lens through which to consider and reflect upon meaningful care provision in this particular care environment. By drawing on available FCC research, we consider how the SOC concepts considered from both a parental and professional perspective need to be addressed. The ...
Source: BMC Pediatrics - Latest articles - May 22, 2013 Category: Pediatrics Authors: Gill ThomsonVictoria Hall MoranAnna AxelinFiona DykesRenée Flacking Source Type: research

The burden of rotavirus gastroenteritis and hospital-acquired rotavirus gastroenteritis among children aged less than 6 years in Japan: a retrospective, multicenter epidemiological survey
Conclusions: Both community- and hospital-acquired rotavirus gastroenteritis are significant public health problems in Japan. Data from this study justify the need for the introduction and implementation of rotavirus vaccination in the Japanese national immunization program.Trial registration: ClinicalTrials.gov, NCT01202201 (Source: BMC Pediatrics - Latest articles)
Source: BMC Pediatrics - Latest articles - May 22, 2013 Category: Pediatrics Authors: Hitoshi TajiriYuriko TakeuchiTomoko TakanoToshihiro OhuraAyano InuiKimie YamamotoYoshihito HigashidateHisashi KawashimaShigeru ToyodaKosuke UshijimaGunasekaran RamakrishnanMats RosenlundKatsiaryna Holl Source Type: research

Evaluation of functional skills and self care of Down's syndrome people included in therapeutic workshop
OBJETIVO: avaliar as habilidades funcionais e de auto cuidado de indivíduos com Síndrome de Down em uma oficina interdisciplinar terapêutica. MÉTODO: investigação prospectiva, exploratória, comparativa, de corte transversal e abordagem quantitativa com amostra de um grupo teste(T), com síndrome de Down (N=17) e, grupo controle (C) sem a síndrome (n= 20). O instrumento utilizado foi o Inventario de avaliação pediátrica (PEDI) que avalia aspectos funcionais do desempenho de crianças. RESULTADOS: a amostra foi pareada (idade média 5 a 7 ½ anos,desvio padrão 1a 6 meses). O grupo T apresentou um repertório de h...
Source: Revista CEFAC - May 21, 2013 Category: Speech Therapy Source Type: research

Abducens palsy as a clue of unexpected contralateral cerebral sinovenous thrombosis
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - May 21, 2013 Category: Pediatrics Authors: Marco Piastra, Maria Fioretti, Daniele Luca, Giorgio Conti, Donato Rigante Tags: Letter to the Editor Source Type: research

Multifactorial intervention for children with asthma and overweight (Mikado): study design of a randomised controlled trial
DiscussionIn this randomised controlled trial we will study the potential of a multifactorial weight reduction intervention to improve asthma-related outcome measures in asthmatic children with overweight. Moreover, it will provide information about the underlying mechanisms in the relationship between asthma and a high body weight in children. These findings can contribute to optimal management programs and better clinical guidelines for children with asthma and overweight.Trial registration: Clinicaltrial.gov NCT00998413 (Source: BMC Public Health - Latest articles)
Source: BMC Public Health - Latest articles - May 21, 2013 Category: Consumer Health News Authors: Maartje WilleboordseKim van de KantMaroeska de LaatOnno van SchayckSandra MulkensEdward Dompeling Source Type: research

Deceased donor liver transplantation in infants and small children: Are partial grafts riskier than whole organs?
Conclusions: Deceased‐donor partial liver transplantation has become less risky over time, and now has comparable outcomes to whole liver transplantation in infants and young children. This study supports the use of partial DD liver grafts in young children in an attempt to significantly increase the pediatric organ pool. Liver Transpl, 2013. © 2013 AASLD. (Source: Liver Transplantation)
Source: Liver Transplantation - May 21, 2013 Category: Transplant Surgery Authors: Ryan P. Cauley, Khashayar Vakili, Kristina Potanos, Nora Fullington, Dionne A. Graham, Jonathan A. Finkelstein, Heung Bae Kim Tags: Original Article Source Type: research

Case series: Elevated lead levels following ingestion of sinkers
(Source: Journal of Paediatrics and Child Health)
Source: Journal of Paediatrics and Child Health - May 21, 2013 Category: Pediatrics Authors: Kate McCloskey, Winita Hardikar, Noel Cranswick Tags: Instructive Case Source Type: research

Moyamoya syndrome in a Malaysian child with Down syndrome
(Source: Journal of Paediatrics and Child Health)
Source: Journal of Paediatrics and Child Health - May 21, 2013 Category: Pediatrics Authors: Sunitha Vimalesvaran, Nachal Nachiappan, Yogeswery Sithamparanathan Tags: Instructive Case Source Type: research

Emergency department presentations by Aboriginal children: Issues for consideration for appropriate health services
ConclusionsA significant proportion of ED presentations were potentially preventable with the use of culturally appropriate and accessible local community and primary health care services and better referral pathways back to these services. Community engagement is required to raise awareness of common presentations and to look at strategies to prevent common problems both occurring and presenting to the ED. This will enhance the health of urban Aboriginal children. (Source: Journal of Paediatrics and Child Health)
Source: Journal of Paediatrics and Child Health - May 21, 2013 Category: Pediatrics Authors: Catriona Duncan, Katrina Williams, Dania Nathanson, Susan Thomas, Carolyn Cottier, Matthew O'Meara, Karen Zwi Tags: Original Ariticle Source Type: research

Prevalence, associated risk factors and antimicrobial susceptibility pattern of Campylobacter species among under five diarrheic children at Gondar University Hospital, Northwest Ethiopia
Conclusion: Isolation rate of Campylobacter species were frequent among under five children. The frequency was higher in those children who were malnourished, drinking of unprotected water and direct contact with infected animals (especially cats, dogs, pigeons, hens and their products). The antimicrobial resistance patterns for some of the commonly prescribed antibiotics were high. Therefore, awareness of hand washing and proper boiling of drinking water are probably important in preventing infection with Campylobacter species and childhood diarrhea should not be underestimated and effectiveness of the drugs should be con...
Source: BMC Pediatrics - Latest articles - May 21, 2013 Category: Pediatrics Authors: Ayalew LengerhFeleke MogesChandrashekhar UnakalBelay Anagaw Source Type: research

Manipulation of drugs to achieve the required dose is intrinsic to paediatric practice but is not supported by guidelines or evidence
Conclusion: Manipulations to achieve the required dose occur throughout paediatric in-patient settings. The impact of manipulations on the efficacy of the drugs, the accuracy of the dose and any adverse effects on patients is not known. There is a need to develop evidence-based guidance for manipulations of medicines in children. (Source: BMC Pediatrics - Latest articles)
Source: BMC Pediatrics - Latest articles - May 21, 2013 Category: Pediatrics Authors: Roberta RicheyUtpal ShahMatthew PeakJean CraigJames FordCatrin BarkerAnthony NunnMark Turner Source Type: research

CDC issues guidance for Pentacel, Daptacel and Pediarix shortages [NEWS AND FEATURES]
(Source: AAP News)
Source: AAP News - May 21, 2013 Category: Pediatrics Authors: O'Connell, P. M. Tags: NEWS AND FEATURES Source Type: research

Sample volume matters when sampling saliva in paediatric clinical analysis
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - May 21, 2013 Category: Pediatrics Authors: Evalotte Morelius, Elvar Theodorsson, Nina Nelson Tags: Letter Source Type: research

Rights-based services for adolescents living with HIV: adolescent self-efficacy and implications for health systems in Zambia
Abstract: A rights-based approach in HIV service delivery for adults is increasingly taking root in sub-Saharan Africa in the context of greater availability of antiretroviral therapy. Yet there has been comparatively little progress in strengthening a rights-based approach to adolescent HIV services, which we learned during a qualitative study in 2010 among 111 adolescents living with HIV, 21 parents and 38 health providers in three districts in Zambia. Adolescents in the study expressed a range of information and support needs and wanted locally relevant interventions to meet those needs. They wanted greater access to HI...
Source: Reproductive Health Matters - May 20, 2013 Category: Global & Universal Authors: Gitau Mburu, Ian Hodgson, Anja Teltschik, Mala Ram, Choolwe Haamujompa, Divya Bajpai, Beatrice Mutali Source Type: research

Childhood ADHD Linked to Obesity in Adulthood
Identification and treatment issues surrounding attention deficit hyperactivity disorder (ADHD) are challenging enough. Now research is shedding light on long-term outcomes for people with ADHD. A May 20 study in Pediatrics reports that men who had ADHD in childhood are twice as likely to be obese in middle age, even if they no longer exhibit symptoms of the disorder. [More] (Source: Scientific American - Official RSS Feed)
Source: Scientific American - Official RSS Feed - May 20, 2013 Category: Science Tags: Health,Thought & Cognition,Addiction Recovery,Psychology,Mind Brain,Society Policy Source Type: research

Abiotrophia Endocarditis in Children with No Underlying Heart Disease: A Rare but a Virulent Organism
We report two cases of Abiotrophia infective endocarditis in children without any predisposing factors. Both patients presented with nonspecific symptoms leading to delay in diagnosis. While bacteriological clearance was achieved in both cases, both had a complicated course including development of brain mycotic aneurysms, splenic infarction, renal failure, and irreversible damage to the mitral valve. Both patients required surgical removal of the native mitral valve and replacement. We also present review of seven cases with similar diagnosis published previously in literature and highlight important differences. Our case...
Source: Congenital Heart Disease - May 20, 2013 Category: Cardiology Authors: Deepti P. Bhat, Lakshmi Nagaraju, Basim I. Asmar, Sanjeev Aggarwal Tags: Case Report Source Type: research

Aortic Dissection in Hospitalized Children and Young Adults: A Multiinstitutional Study
Conclusions.AD is rare in children and young adults but most commonly occurs in CHD and CTD and in males. AD is associated with high inpatient mortality. (Source: Congenital Heart Disease)
Source: Congenital Heart Disease - May 20, 2013 Category: Cardiology Authors: Pirouz Shamszad, Jeff N. Barnes, Shaine A. Morris Tags: Original Article Source Type: research

Establishing reference intervals for electrolytes in newborns and infants using direct ISE analyzer
Conclusion: Combined RIs are suggested for the interpretation of electrolyte values in newborns and infants without taking the effect of maternal, neonatal and infantile factors into account. Since the RIs were different from previously reported values, it will be appropriate to apply such RIs for the interpretation of electrolyte values in Ethiopian pediatric population. (Source: BMC Research Notes)
Source: BMC Research Notes - May 20, 2013 Category: Research Authors: Mulugeta MelkieMahilet YigeremuPaulos NigussieTilahun TekaSamuel Kinde Source Type: research

Yes, we can – achieve adequate early postnatal growth in very preterm infants
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - May 20, 2013 Category: Pediatrics Authors: C. Maas, C. F. Poets, A. R. Franz Tags: Letter to the Editor Source Type: research

Can the Retinal Microvasculature offer Clues to Cardiovascular Risk Factors in Early Life?
Conclusion This review supports the theory that major vascular diseases has pathological predisposition early in life by providing morphological evidence on retinal microcirculation in vivo. This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - May 20, 2013 Category: Pediatrics Authors: Ling‐Jun Li, Yung‐Seng Lee, Tien‐Yin Wong, Carol Yim‐Lui Cheung Tags: Review Article Source Type: research

Bench‐top accuracy of SiPAP‐generated nasal intermittent positive pressure ventilation
(Source: Acta Paediatrica)
Source: Acta Paediatrica - May 20, 2013 Category: Pediatrics Authors: LS Owen, CJ Morley, PG Davis Tags: Short Communication Source Type: research

Screening of the Families of the Cases with Left‐sided Cardiovascular Anomalies
ConclusionsBAV and other LSCAs are of clinical significance. Because the clustering of LSCAs in some families is observed, we recommend echocardiographic screening of those relatives. If not possible, at least it should be achieved for BAV. (Source: Pediatrics International)
Source: Pediatrics International - May 20, 2013 Category: Pediatrics Authors: Fikri Demir, Cem Karadeniz, Semra Atalay, Mustafa Tekin, Ercan Tutar Tags: Original Article Source Type: research

Pragmatic controlled trial to prevent childhood obesity in maternity and child health care clinics: pregnancy and infant weight outcomes (The VACOPP Study)
Conclusion: Since the intervention reduced the prevalence of gestational diabetes mellitus, it may have the potential to diminish obesity risk in offspring. However, results from earlier studies suggest that the possible effect on the offspring's weight gain may manifest only later in childhood.Trial registration: Clinical Trials gov: NCT00970710 (Source: BMC Pediatrics - Latest articles)
Source: BMC Pediatrics - Latest articles - May 20, 2013 Category: Pediatrics Authors: Taina MustilaJani RaitanenPäivi KeskinenAntti SaariRiitta Luoto Source Type: research