Pediatrics Research This is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 24.
Sacrococcygeal myxopapillary ependymoma with anaplastic ependymoma component in an infant
We report a rare case of sacrococcygeal MPE in an 11-month-old female child who showed typical myxopapillary ependymal histology along with anaplastic ependymal component. Ki-67 labeling index in the myxopapillary component was 4-5% and in the anaplastic component was 70%. Six weeks after gross total resection of the tumor, the child presented with local recurrence and metastasis in the right inguinal lymph nodes and was treated with chemotherapy. The present case of sacrococcygeal MPE with anaplastic ependymoma component is the second case on record in the medical literature, and the first case without any s...
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Shrijeet ChakrabortiHema KiniK Ganesh PaiVidya Upadhyaya Source Type: research
Superficial siderosis: A rare occurrence in children
We present the case of a twelve-year-old boy who had a surgery of the posterior fossa at the age of two years and then developed recurrent headaches, instability of gait, and hearing deficit at around ten years of age. Clinical examination revealed progressive ataxia and mild sensorineural hearing loss. He also had infrequent seizures with mild electroencephalographic abnormality. His serial magnetic resonance imaging (MRIs) showed a progressive deposition of hemosiderin in the cerebellar folia and around the brainstem, confirming a diagnosis of superficial siderosis. This case report draws attention to this rare condition...
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Trupti M JadhavAnaita U Hegde Source Type: research
Chondromyxoid fibroma of the temporal bone: A rare entity
We report one such case involving the temporal bone. Till date, only nine such cases including this patient, involving the temporal bone have been reported to the best of our knowledge. Grant Medical College and Sir J.J Group of Hospitals, Byculla, Mumbai, Maharashtra, India. A 12-year-old female patient presented with a history of headache associated with left earache of 1 month duration. This was followed by swelling over the left preauricular region 15 days later. Imaging was suggestive of an expansile lesion involving the squamous part of the left temporal bone with calcifications suggestive of a benign chondroid lesio...
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Mayur SharmaVernon VelhoRachana BinayakeChandranath Tiwari Source Type: research
Intracerebral metastasis in pediatric acute lymphoblastic leukemia: A rare presentation
Müge Gokce, Selin Aytac, Ilhan Altan, Sule Unal, Murat Tuncer, Fatma Gumruk, Mualla CetinJournal of Pediatric Neurosciences 2012 7(3):208-210Central nervous system leukemia may present in different ways. However, intraparenchymal mass is extremely rare in childhood leukemia. Herein, we report a boy who presented with right hemiparesis and anisocoria 1 year after the cessation of the chemotherapy protocol for acute lymphoblastic leukemia. Cranial imaging demonstrated an extensive mass located in the anterior white matter of left frontal lobe, and cerebrospinal fluid examination revealed concomitant lymphoblasts. Immu...
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Müge GokceSelin AytacIlhan AltanSule UnalMurat TuncerFatma GumrukMualla Cetin Source Type: research
Lateral intraventricular epidermoid in a child with hydrocephalus
We report a rare case of large bulky right intraventricular epidermoid tumor in a child. This tumor was associated with mass effect on the surrounding structures and hydrocephalus.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: B Aher RajendraDaljit SinghHukum SinghRK Saran Source Type: research
Precocious puberty due to human chorionic gonadotropin secreting germinoma
This study aims to report a rare case of precocious puberty (PP) due to a human chorionic gonadotropin (hCG)-producing germinoma located in the suprasellar region. A 10-year-old male patient presented with sexual precocity, headache, drowsiness, loss of appetite, and papilledema. Significant acceleration of bone age in relation to chronological age, high serum total testosterone levels, and hypopituitarism (unresponsiveness to stimulation test) were observed. Magnetic resonance imaging (MRI) of the brain showed a large suprasellar tumor and triventricular dilatation. High hCG levels were found in both blood and cerebrospin...
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Daiane J NascimentoCarolina G.S LeãesJulia F.S. Pereira-LimaMiriam C Oliveira Source Type: research
Multiple cerebral cavernous haemangiomas in an infant
We report a 20-month old male with multiple CCMs associated with Krev interaction trapped 1 (KRIT1) c.845 + 1 G > C heterozygous transversion mutation. This case demonstrates the importance of molecular genetic analysis in cases of multiple CCM.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Poonam VermaRashid SaleemPooja HarijanNahin Hussain Source Type: research
Heterogeneity in spinal muscular atrophy with respiratory distress type 1
This report describes a male infant with genetically confirmed SMARD1 presenting with onset of disease in the first two weeks of life with respiratory compromise and urinary retention, which has not been reported before and adds to the phenotypic variability of SMARD 1.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Aziz MajidKhan TalatLumsden ColinRoss CarolineKingston HelenDe Goede Christian Source Type: research
Spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis
Muge GokceJournal of Pediatric Neurosciences 2012 7(3):194-196The involvement of the central nervous system (CNS) in familial hemophagocytic lymphohistiocytosis (FHL) has known to be limited to the brain, brain stem, and cerebellum. Herein, we report an 11-year-old boy who presented with neurological symptoms and was diagnosed as FHL by molecular diagnosis. The hemophagocytic lesions in the CNS were shown to extend to the thoracal level of spinal cord which completely disappeared after the completion of hemophagocytic lymphohistiocytosis-2004 protocol.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Muge Gokce Source Type: research
Scoliotic deformity and asymptomatic cervical syrinx in a 9 year old with caudal regression syndrome
We report late presentation of caudal regression syndrome in a 9 year old presenting with a scoliotic deformity. She in addition had an asymptomatic cervical syrinx and vitiligo. We discuss the reasons for this unusual constellation of symptomatology present in our case.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Ankur SinghSeema KapoorGaurav PradhanVK GautamSimmi K Ratan Source Type: research
Neurenteric cyst of the ventral cervicomedullary region
G Lakshmi Prasad, Sachin Anil Borkar, Kiran Chikkanahalli Subbarao, Mehar Chand Sharma, Ashok Kumar MahapatraJournal of Pediatric Neurosciences 2012 7(3):188-190Neurenteric cysts are rare, benign, endodermally derived tumors of the central nervous system. Intracranial neurenteric cysts are rare with posterior fossa being the most common location among them. Neurenteric cyst of the craniocervical region is very rare. Authors report a rare case of neurenteric cyst located in the ventral cervicomedullary region. The pertinent literature is reviewed regarding this uncommon entity.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: G Lakshmi PrasadSachin Anil BorkarKiran Chikkanahalli SubbaraoMehar Chand SharmaAshok Kumar Mahapatra Source Type: research
Acalvaria: A rare congenital malformation
Vipul Gupta, Sunil KumarJournal of Pediatric Neurosciences 2012 7(3):185-187Acalvaria is described as a rare congenital malformation in a 1-month-old female baby who presented with classical clinical features of soft, lax skull as a result of absent skull bones and associated muscles. Acalvaria is usually a fatal anomaly and is rarely discussed in English literature. Thus, we herein report a living case of acalvaria along with a review of the literature.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Vipul GuptaSunil Kumar Source Type: research
Neurocristic cutaneous hamartoma of the scalp
We describe the clinicopathologic features of an example occurring in a 2-month-old girl presenting with a large parietooccipital swelling. The literature is reviewed.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Mazda K TurelGeeta ChackoA RajaBernd W Scheithauer Source Type: research
GM1gangliosidosis: Clinical and radiological clue to diagnosis
We describe a case of GM1gangliosidosis with dysostosis multiplex and characteristic magnetic resonance imaging findings.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Renu SutharJitendra K SahuPratibha Singhi Source Type: research
Muscular myopathies other than myotonic dystrophy also associated with (CTG) n expansion at the DMPK locus
Conclusion: Results suggest a role of (CTG) n expansion at the DMPK locus in unexplained hypotonias and muscular myopathies other than DM. This calls for screening of the triplet repeat expansion at the DMPK locus in cases of idiopathic myopathies and hypotonia.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Vasavi MohanYR AhujaQurratulain Hasan Source Type: research
Effective dose of topiramate in pediatric migraine prophylaxis
Conclusion: The results of this study demonstrated that low-dose of topiramate (<2 mg/kg/day) is effective, well-tolerated, safe, and suggested as an alternative prophylactic treatment for pediatric migraine.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: Ali AbbaskhanianHamid Reza SadeghiAli ErfaniMohammad Sadegh Rezai Source Type: research
Split cord malformation with dorsally located bony spur: Report of four cases and review of literature
GL Prasad, Sachin A Borkar, GD Satyarthee, AK MahapatraJournal of Pediatric Neurosciences 2012 7(3):167-170Split cord malformations (SCM) with a dorsally located bony spur are a very rare entity. The authors report a series of four such cases. The literature is reviewed regarding the pathogenesis and management of this uncommon variant of SCM. The presenting features include - scoliosis with motor and autonomic dysfunction (n = 1), scoliosis with cutaneous patch (n = 1), hypertrichotic area (n = 1), and motor deficits alone (n = 1). The location of spur was thoracic and lumbar in two patients (50%) each. Low-lying c...
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: GL PrasadSachin A BorkarGD SatyartheeAK Mahapatra Source Type: research
Abdominal epilepsy in chronic recurrent abdominal pain
Conclusions: A diagnosis of AE must be considered in children with chronic recurrent abdominal pain, especially in those with suggestive history, and an EEG can save a child from lot of unnecessary investigations and suffering.
Source: Journal of Pediatric Neurosciences - January 25, 2013 Category: Neuroscience Authors: VY KshirsagarSuhel NagarsenkarMinhajuddin AhmedSylvia ColacoKC Wingkar Source Type: research
Clozapine in Severe Conduct Disorder
Journal of Child and Adolescent Psychopharmacology , Vol. 0, No. 0.
Source: Journal of Child and Adolescent Psychopharmacology - January 24, 2013 Category: Pediatrics Tags: article Source Type: research
Answers to CME questions
Perinatal exposure to nicotine and implications for subsequent obstructive lung disease A 1 True, 2 True, 3 True, 4. False, 5. True
Source: Paediatric Respiratory Reviews - January 24, 2013 Category: Respiratory Medicine Tags: Answers to CME Questions 2012 Source Type: research
Accessible and diverse educational strategies
The art of medicine consists of amusing the patient while nature cures the disease. ∼Voltaire We would like to think much progress has been made over the last 300 years in medicine. These include chest radiographs, antibiotics, computer imaging and of course electronic billing for those in private practice. Beyond the tools of the trade there is the approach to teaching and learning that is so fundamental to medicine. Varying phenotypes of physicians as clinicians and educators have been previously suggested, but clearly these only apply to colleagues working at other institutions. In recognition of the fact that others...
Source: Paediatric Respiratory Reviews - January 24, 2013 Category: Respiratory Medicine Authors: Dominic A. Fitzgerald Tags: Main Editorial Source Type: research
Impact of antenatal glucocorticosteroids on whole genome expression in preterm babies
ConclusionAntenatal steroid therapy affects a limited number of genes and gene pathways in leukocytes in preterm babies at day five of life. The effect is short lived, but long‐term effects cannot be ruled out.©2013 The Author(s)/Acta Pædiatrica ©2013 Foundation Acta Pædiatrica
Source: Acta Paediatrica - January 24, 2013 Category: Pediatrics Authors: Ola Didrik Saugstad, Przemko Kwinta, Embjørg Julianne Wollen, Mirosław Bik – Multanowski, Anna Madetko – Talowska, Mateusz Jagła, Tomasz Tomasik, Jacek Józef Pietrzyk Tags: Regular Article Source Type: research
The relation of serum nesfatin‐1 level with metabolic and clinical parameters in obese and healthy children
ConclusionsThis is the first study to evaluate nesfatin‐1 levels in relation with anthropometric and metabolic parameters in obese patients who had significantly lower nesfatin‐1 levels. Our results underline that nesfatin‐1 may play an important role in regulation of food intake in obese individuals.
Source: Pediatric Diabetes - January 24, 2013 Category: Endocrinology Authors: Ayhan Abaci, Gonul Catli, Ahmet Anik, Tuncay Kume, Ece Bober Tags: Original Article Source Type: research
Two Different Solicitation Methods for Obtaining Information on Adverse Events Associated with Methylphenidate in Adolescents: A 12-Week Multicenter, Open-Label Study
Journal of Child and Adolescent Psychopharmacology , Vol. 0, No. 0.
Source: Journal of Child and Adolescent Psychopharmacology - January 24, 2013 Category: Pediatrics Tags: article Source Type: research
Simultaneous Sequencing of 24 Genes Associated with Steroid-Resistant Nephrotic Syndrome.
CONCLUSIONS: This study shows that next generation sequencing analysis of pediatric steroid-resistant nephrotic syndrome patients is accurate and revealing. This analysis should be considered part of the routine genetic workup of diseases such as childhood steroid-resistant nephrotic syndrome, where the chance of genetic mutation is high but requires sequencing of multiple genes. PMID: 23349334 [PubMed - as supplied by publisher]
Source: Clinical Journal of the American Society of Nephrology : CJASN - January 24, 2013 Category: Urology & Nephrology Authors: McCarthy HJ, Bierzynska A, Wherlock M, Ognjanovic M, Kerecuk L, Hegde S, Feather S, Gilbert RD, Krischock L, Jones C, Sinha MD, Webb NJ, Christian M, Williams MM, Marks S, Koziell A, Welsh GI, Saleem MA, on behalf of RADAR, the UK SRNS Study Group Tags: Clin J Am Soc Nephrol Source Type: research
[Clinical impact of introducing ventilation with high flow oxygen in the treatment of bronchiolitis in a paediatric ward.]
CONCLUSIONS: High-flow ventilation therapy achieved a significant improvement in heart rate, respiratory rate, and scale of severity in patients with bronchiolitis. This novel therapeutic strategy allows safe management of bronchiolitis patients in the regular ward, reducing admissions to the PICU. PMID: 23352386 [PubMed - as supplied by publisher]
Source: Anales de Pediatria - January 24, 2013 Category: Pediatrics Authors: González Martínez F, González Sánchez MI, Rodríguez Fernández R Tags: An Pediatr (Barc) Source Type: research
Multicenter Spanish study of spectral‐domain optical coherence tomography in normal children
Conclusions: Normative paediatric SD‐OCT data might facilitate use of SD‐OCT for assessing childhood ophthalmic diseases. This study provides a multicenter paediatric normative database of SD‐OCT peripapillary RNFL and macular data.
Source: Acta Ophthalmologica - January 24, 2013 Category: Opthalmology Authors: Jesús Barrio‐Barrio, Susana Noval, Marta Galdós, Miguel Ruiz‐Canela, Elvira Bonet, María Capote, Maialen Lopez Source Type: research
Different effects of HLA disparity on transplant outcomes after single-unit cord blood transplantation between pediatric and adult patients with leukemia.
Conclusions The effect of HLA disparity on transplant outcome differed between children and adults. In children, an increased number of mismatched HLA loci correlated with an increased risk of mortality. In adults, there was no increase in mortality with an increase in the number of mismatched HLA loci. PMID: 23349300 [PubMed - as supplied by publisher]
Source: Haematologica - January 24, 2013 Category: Hematology Authors: Atsuta Y, Kanda J, Takanashi M, Morishima Y, Taniguchi S, Takahashi S, Ogawa H, Ohashi K, Ohno Y, Onishi Y, Aotsuka N, Nagamura-Inoue T, Kato K, Kanda Y Tags: Haematologica Source Type: research
NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia.
Conclusions: Mutations of PTEN highly significantly indicate a poor prognosis in patients who have been stratified to the medium risk group of the BFM-protocol. This effect is clinically neutralized by NOTCH1 mutations. Although these results are not yet explained by an obvious molecular mechanism, they contribute to the development of new molecularly defined stratification algorithms. Furthermore, these data have unexpected potential implications for the development of NOTCH1 inhibitors in the treatment of T-cell acute lymphoblastic leukemia in general and in those with a combination of PTEN and NOTCH1 mutations in partic...
Source: Haematologica - January 24, 2013 Category: Hematology Authors: Bandapalli OR, Zimmermann M, Kox C, Stanulla M, Schrappe M, Ludwig WD, Koehler R, Muckenthaler MU, Kulozik AE Tags: Haematologica Source Type: research
Comparison of the effects of dexmedetomidine, ketamine, and placebo on emergence agitation after strabismus surgery in children.
CONCLUSIONS: Dexmedetomidine and ketamine appear to prevent postoperative agitation and pain after sevoflurane anesthesia for pediatric strabismus surgery. Dexmedetomidine also prevents POV. PMID: 23344921 [PubMed - as supplied by publisher]
Source: Canadian Journal of Anaesthesia - January 24, 2013 Category: Anesthesiology Authors: Chen JY, Jia JE, Liu TJ, Qin MJ, Li WX Tags: Can J Anaesth Source Type: research
Epstein–Barr Virus Infection and Posttransplant Lymphoproliferative Disorder
Epstein–Barr virus (EBV) is an important pathogen in recipients of solid organ transplants (SOT). Infection with EBV manifests as a spectrum of diseases/malignancies ranging from asymptomatic viremia through infectious mononucleosis to posttransplant lymphoproliferative disorder (PTLD). EBV disease and its associated PTLD is more frequently seen when primary EBV infection occurs after transplant, a common scenario in pediatric SOT recipients. Intensity of immunosuppressive therapies also influences the risk for PTLD. The use of EBV viral load monitoring facilitates the diagnosis and management of EBV/PTLD as well as bein...
Source: American Journal of Transplantation - January 24, 2013 Category: Transplant Surgery Authors: M. Green, M. G. Michaels Tags: Continuing Medical Education Source Type: research
Current options for management of biliary atresia
Abstract It is encouraging that we are improving the technical aspects of treatment modalities for biliary atresia. However, it is clear that more needs to be done to best develop new treatment plans while applying the modalities we have (porto‐enterostomy or liver transplantation or both) in a way that will afford the best survival and quality‐of‐life. This review article will discuss a number of points that are vital to improving care and illustrates the need to further scrutinize treatment decisions.
Source: Pediatric Transplantation - January 24, 2013 Category: Transplant Surgery Authors: Amy Gallo, Carlos O. Esquivel Tags: Review Article Source Type: research
Liver transplantation for urea cycle disorders in pediatric patients: A single‐center experience
Abstract LT has emerged as a surgical treatment for UCDs. We hypothesize that LT can be safely and broadly utilized in the pediatric population to effectively prevent hyperammonemic crises and potentially improve neurocognitive outcomes. To determine the long‐term outcomes of LT for UCDs, charts of children with UCD who underwent LT were retrospectively reviewed at an academic institution between July 2001 and May 2012. A total of 23 patients with UCD underwent LT at a mean age of 3.4 yr. Fifteen (65%) patients received a whole‐liver graft, seven patients (30%) received a reduced‐size graft, and one patient received...
Source: Pediatric Transplantation - January 24, 2013 Category: Transplant Surgery Authors: Irene K. Kim, Anna‐Kaisa Niemi, Casey Krueger, Clark A. Bonham, Waldo Concepcion, Tina M. Cowan, Gregory M. Enns, Carlos O. Esquivel Tags: Original Article Source Type: research
Transumbilical single‐incision laparoscopic ileocecal resection for Crohn's disease in a child
We report the pediatric case of ileal Crohn's disease in which the patient underwent transumbilical single‐incision laparoscopic ileocecal resection. A 14‐year‐old boy with severe growth disturbance presented with intestinal obstruction. Transanal double‐balloon enteroscopy and contrast study during endoscopy revealed a cobble stone appearance and a severe stricture 15 cm in length located slightly proximal to the ileocecal valve. There was no evidence of fistula or abscess formation. Ileocecal resection was performed via an umbilical incision with conventional laparoscopic instruments, and the postoperative cour...
Source: Asian Journal of Endoscopic Surgery - January 24, 2013 Category: Surgery Authors: Mikihiro Inoue, Keiichi Uchida, Kohei Otake, Masato Okigami, Yoshiki Okita, Junichiro Hiro, Toshimitsu Araki, Masato Kusunoki Tags: Case Report Source Type: research
Socio-demographic determinants of hearing impairment studied in 103 835 term babies
Conclusions: The socio-demographic factors found to be associated with CHI extend the list of classic risk factors as defined by the American Academy of Pediatrics (AAP). Assessment of these additional factors may alert the treating physician to the increased risk of newborn hearing impairment and urge the need for accurate follow-up. Moreover, this extended assessment may improve decision making in medical practice and screening policy.
Source: The European Journal of Public Health - January 24, 2013 Category: Journals (General) Authors: Van Kerschaver, E., Boudewyns, A. N., Declau, F., Van de Heyning, P. H., Wuyts, F. L. Tags: Social Determinants Source Type: research
Hemophagocytic lymphohistiocytosis in syntaxin-11-deficient mice: T-cell exhaustion limits fatal disease
Syntaxin-11 (Stx11), an atypical member of the SNARE protein family, is part of the cytolytic machinery of T and NK cells and involved in the fusion of lytic granules with the plasmamembrane. Functional loss of syntaxin-11 in humans causes defective degranulation and impaired cytolytic activity of T and NK cells. Furthermore, patients with STX11 deficiency develop familial hemophagocytic lymphohistiocytosis type 4 (FHL4), a life-threatening disease of severe hyperinflammation. We established Stx11-deficient mice as an animal model for FHL4. Stx11-deficient mice exhibited severely reduced degranulation and cytolytic activit...
Source: Blood - January 24, 2013 Category: Hematology Authors: Kogl, T., Muller, J., Jessen, B., Schmitt-Graeff, A., Janka, G., Ehl, S., zur Stadt, U., Aichele, P. Tags: Pediatric Hematology, Immunobiology, Free Research Articles Source Type: research
Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11
Inherited defects of granule-dependent cytotoxicity led to the life-threatening immune disorder hemophagocytic lymphohistiocytosis (HLH), characterized by uncontrolled CD8 T-cell and macrophage activation. In a cohort of HLH patients with genetic abnormalities expected to result in the complete absence of perforin, Rab27a, or syntaxin-11, we found that disease severity as determined by age at HLH onset differed significantly, with a severity gradient from perforin (early onset) > Rab27a > syntaxin-11 (late onset). In parallel, we have generated a syntaxin-11–deficient (Stx11–/–) murine model that fa...
Source: Blood - January 24, 2013 Category: Hematology Authors: Sepulveda, F. E., Debeurme, F., Menasche, G., Kurowska, M., Cote, M., Pachlopnik Schmid, J., Fischer, A., de Saint Basile, G. Tags: Pediatric Hematology, Immunobiology, Free Research Articles Source Type: research
BET 3: Management of paediatric minor head injuries: safe discharge?
Report by: Dr Fiona Hunter, ST4 Emergency Medicine Search checked by: Dr Vincent Choudhery, Consultant in Paediatric Emergency Medicine Institution: Yorkhill Hospital, Glasgow, UK Abstract A short-cut review was carried out to establish whether the finding of a normal cranial CT scan, in a child with a history of minor head injury, a Glasgow coma scale (GCS) score of 15 and normal neurological examination could facilitate safe discharge from hospital. Ninety-eight articles were found using the reported search and a further two papers were found from the references of selected papers. A total of 11 trials were included with...
Source: Emergency Medicine Journal - January 24, 2013 Category: Emergency Medicine Tags: EMJ Best evidence topic reports, Patients, Coma and raised intracranial pressure, Trauma CNS / PNS, Radiology, Clinical diagnostic tests, Radiology (diagnostics), Trauma Source Type: research
Drug-induced movement disorders in children at paediatric emergency department: 'dystonia'
Conclusion Dystonia is a common side effect of certain drugs, even when therapeutic doses are administered. Although the most common DIDRs were abnormal postures of the head and neck, rare life-threatening conditions, may develop particularly due to use of antipsychotics. In treatment, diphenhydramine could effectively be used through parenteral way to eliminate the cholinergic effects of those drugs. However, the easiest and the safest way to prevent the development of DRs is to avoid unnecessary drug usage. In conclusion, physicians should be aware that antiemetic and antipsychotic drugs are associated with DRs in normal...
Source: Emergency Medicine Journal - January 24, 2013 Category: Emergency Medicine Authors: Derinoz, O., Caglar, A. A. Tags: Child and adolescent psychiatry (paedatrics), Psychotic disorders (incl schizophrenia), Ear, nose and throat/otolaryngology Original articles Source Type: research
Sodium valproate induced increased frequency of micturition and enuresis
We present a case of sodium valproate induced enuresis in child. This ADR of valproate is an underreported ADR and requires special attention of pediatricians as it can interfere with the further treatment of the disease.
Source: Indian Journal of Pharmacology - January 24, 2013 Category: Drugs & Pharmacology Authors: Devesh D GosaviAkanksha SumanManish Jain Source Type: research
Validation of the Hong Kong Oral Health Literacy Assessment Task for Paediatric Dentistry (HKOHLAT‐P)
ConclusionInitial testing of HKOHLAT‐P suggested that it is a valid and reliable instrument.
Source: International Journal of Paediatric Dentistry - January 24, 2013 Category: Dentistry Authors: Hai Ming Wong, Susan M. Bridges, Cynthia K. Y. Yiu, Colman P. J. McGrath, Terry K. Au, Divya S. Parthasarathy Tags: Original Article Source Type: research
Nitroglycerin for severe ischaemic injury after peripheral arterial line in a preterm infant
Source: Acta Paediatrica - January 24, 2013 Category: Pediatrics Authors: Rita Kamar, Jeroen J van Vonderen, Enrico Lopriore, Arjan B te Pas Tags: Readers' Forum Source Type: research
Talking via the Child: Discursively Created Interaction Between Parents and Health Care Professionals in a Pediatric Oncology Ward
The aim of this study was to describe discursively constructed interactions between parents and health care professionals (HCPs) in a pediatric oncology ward. Field notes from 70 focused participant observations and 16 informal interviews with 25 HCPs interacting with 25 parents of children with cancer were analyzed using discursive psychology. Six dominant interpretative repertoires (flexible parts of discourses used in everyday interaction) were found. Repertoires used by the HCPs were child, parent, or family oriented, mirroring the primary focus of the interaction. Parents used a spokesperson repertoire to use their ow...
Source: Journal of Family Nursing - January 24, 2013 Category: Nursing Authors: Ringner, A., Oster, I., Bjork, M., Graneheim, U. H. Tags: Articles Source Type: research
Calendar of Events
Source: International Journal of Pediatric Otorhinolaryngology - January 23, 2013 Category: ENT & OMF Source Type: research
Supporting children with hearing and vestibular problems is a complex and challenging process. Whereas textbooks provide important foundations for audiological assessment and intervention for children, case studies can be an important supplementary tool for putting concepts in the context of the clinical process. The Pediatric Audiology Casebook was written to compliment Madell and Flexer's textbook Pediatric Audiology: Diagnosis, Technology and Management , supporting the theoretical concepts with over 65 in-depth case studies. The topics range broadly from basic pediatric audiological assessment to multifaceted examples ...
Source: International Journal of Pediatric Otorhinolaryngology - January 23, 2013 Category: ENT & OMF Authors: Ryan McCreery Tags: Book reviews Source Type: research
Massilia sp. isolated from otitis media
Abstract: Common bacterial pathogens of otitis media include Haemophilus influenzae, Moraxella catarrhalis, Streptococcus pneumoniae, Staphylococcus aureus, Pseudomonas aeruginosa, alpha-hemolytic streptococci, and Group A streptococci. We recently isolated a gram-negative, rod-shaped, non-spore-forming bacterium from a patient with otitis media following tympanocentesis. 16S rRNA gene sequence similarity studies of effusion identified this strain (CCUG 43427AT) as Massilia sp. (99.7%). Massilia spp. have been isolated from soil, air, and immunocompromised patients. However, there are no reports of their isolation from cas...
Source: International Journal of Pediatric Otorhinolaryngology - January 23, 2013 Category: ENT & OMF Authors: Moo Kyun Park, Hee Bong Shin Tags: Case reports Source Type: research
An Usher syndrome type 1 patient diagnosed before the appearance of visual symptoms by MYO7A mutation analysis
This study examined the frequency of USH1 before the appearance of visual symptoms in Japanese deaf children by MYO7A mutation analysis. We report the case of 6-year-old male with profound hearing loss, who did not have visual symptoms. The frequency of MYO7A mutations in profound hearing loss children is also discussed. We sequenced all exons of the MYO7A gene in 80 Japanese children with severe to profound non-syndromic HL not due to mutations of the GJB2 gene (ages 0–14 years). A total of nine DNA variants were found and six of them were presumed to be non-pathogenic variants. In addition, three variants of them were ...
Source: International Journal of Pediatric Otorhinolaryngology - January 23, 2013 Category: ENT & OMF Authors: Hidekane Yoshimura, Satoshi Iwasaki, Yukihiko Kanda, Hiroshi Nakanishi, Toshinori Murata, Yoh-ichiro Iwasa, Shin-ya Nishio, Yutaka Takumi, Shin-ichi Usami Tags: Case reports Source Type: research