Pediatrics Research This is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.
40 men in Canada are playing the world's longest hockey game to raise money for pediatric cancer research. The game will be over 10 days long! For more info or to donate, visit the website.
This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 7.
Subcutaneous panniculitis‐like T‐cell lymphoma in the pediatric age group: A lymphoma of low malignant potential
ConclusionsPediatric SPTCL shares many clinical and pathologic features with adult SPTCL. The presence of partial involvement or admixed plasma cells makes the differential diagnosis with reactive conditions challenging in some cases. Pediatr Blood Cancer © 2013 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - February 4, 2013 Category: Cancer & Oncology Authors: Alison R. Huppmann, Liqiang Xi, Mark Raffeld, Stefania Pittaluga, Elaine S. Jaffe Tags: Research Article Source Type: research
Lurie Children's Hospital ranks 10th in nation
The Ann & Robert H. Lurie Children’s Hospital of Chicago ranked 10th-best nationally of 66 standalone children’s hospitals, according to Parents magazine. The publication released its rankings Monday of the “Best Children’s Hospitals in America” and announced the results on NBC’s “Today Show.” The rankings were decided with input from a team of medical advisers. The magazine ranked the pediatric hospitals based on quality of care. Parents magazine cited Lurie Children's for spending…
Source: bizjournals.com Health Care:Hospitals headlines - February 4, 2013 Category: Hospital Management Source Type: research
Children's Hospital ranks fourth in nation
Children’s Hospital of Wisconsin in Milwaukee ranked fourth-best nationally of 66 standalone children’s hospitals, according to Parents magazine. The publication released its rankings Monday of the “Best Children’s Hospitals in America” and announced the results on NBC’s “Today Show.” The rankings were decided with input from a team of medical advisers. The magazine ranked the pediatric hospitals based on quality of care. Here are the top 10 hospitals, in order: •The Children’s…
Source: bizjournals.com Health Care:Hospitals headlines - February 4, 2013 Category: Hospital Management Authors: Rich Kirchen Source Type: research
[Evaluation of the abstracts submitted to the French Society of Pediatrics (SFP) in 2012.]
PMID: 23391446 [PubMed - as supplied by publisher]
Source: Archives de Pediatrie - February 4, 2013 Category: Pediatrics Authors: Testefort A, Giraudeau B, Lamireau T, Tounian P, Dubus JC, Chabrol B, Bader-Meunier B, Hankard R Tags: Arch Pediatr Source Type: research
[Managing pain in children with cancer in Africa: A survey from the French-African Pediatric Oncology group.]
CONCLUSION: In recent years, pain prevention and relief, whatever its origin, have become a priority for all medical teams, especially for children with cancer. With its profound sociocultural changes, Africa is no exception. All teams in our group are aware of the situation and hope for major improvement in pain management in the near future through increased resources and training. PMID: 23391447 [PubMed - as supplied by publisher]
Source: Archives de Pediatrie - February 4, 2013 Category: Pediatrics Authors: Yao A, Coze C, Traoré F, André N, Moreira C, Pondy A, Randriamihoatra S, Bouda C, Lukamba R, Koffi G, Harif M Tags: Arch Pediatr Source Type: research
[Aneurysmal cyst of ethmoid bone: A case report.]
CONCLUSION: Aneurysmal bone cyst is a benign bone lesion which rarely involves the facial bones. Imaging plays an important role in the diagnostic approach, the assessment of the lesions, and the treatment using the techniques of interventional radiology. PMID: 23391448 [PubMed - as supplied by publisher]
Source: Archives de Pediatrie - February 4, 2013 Category: Pediatrics Authors: Fikri M, Meziane M, El Hassani MR, Ech-Cherif El Kettani N, Essakalli L, Kzadri M, Jiddane M Tags: Arch Pediatr Source Type: research
Management of subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex (TSC): Clinical recommendations.
This report summarizes the clinical recommendations for the management of SEGA made by a panel of European experts in March 2012. Current treatment options and outstanding questions are outlined. PMID: 23391693 [PubMed - as supplied by publisher]
Source: European Journal of Paediatric Neurology - February 4, 2013 Category: Neurology Authors: Jóźwiak S, Nabbout R, Curatolo P, On behalf of the participants of the TSC Consensus Meeting for SEGA and Epilepsy Management Tags: Eur J Paediatr Neurol Source Type: research
Population Pharmacokinetics of Atorvastatin and Its Active Metabolites in Children and Adolescents With Heterozygous Familial Hypercholesterolemia: Selective Use of Informative Prior Distributions from Adults.
Abstract The population pharmacokinetics (PPK) of atorvastatin and its principal active metabolite, o-hydroxyatorvastatin, were described in 6-17 years old pediatric hypercholesterolemia patients with a 2-compartment model for both parent and metabolite. Informative prior distributions on selected parameters, based on adult data, were required to stabilize the model and were implemented using a Bayesian penalty term on the likelihood function in the nonlinear mixed effects model (NONMEM VI with PRIOR). Concentrations below the limit of quantitation were treated as censored data using a conditional likelihood functi...
Source: The Journal of Clinical Pharmacology - February 4, 2013 Category: Drugs & Pharmacology Authors: Knebel W, Gastonguay MR, Malhotra B, El-Tahtawy A, Jen F, Gandelman K Tags: J Clin Pharmacol Source Type: research
Striving for a zero-error patient surgical journey through adoption of aviation-style challenge and response flow checklists: a quality improvement project.
CONCLUSIONS: We have created a reproducible model of care involving multiple checklists at high-risk points in the patient surgical journey. The model is reliable and has a high degree of staff engagement. It promotes patient safety by ensuring the patient, team and equipment are correctly configured at every key transition stage in the surgical journey. We have been able to achieve this with no measurable increase in turnover times or reduction in operating room efficiency. PMID: 23373830 [PubMed - as supplied by publisher]
Source: Paediatric Anaesthesia - February 4, 2013 Category: Anesthesiology Authors: Low DK, Reed MA, Geiduschek JM, Martin LD Tags: Paediatr Anaesth Source Type: research
Development of an Evidence-Based Clinical Guideline for Age-Appropriate Screening, Prevention, and Management of Bone Abnormalities in Children Post-Hematopoietic Stem Cell Transplant.
Abstract Musculoskeletal complaints, pain, and weakness are common among children post-hematopoietic stem cell transplant (HSCT). Bone abnormalities include decreased bone mineral density and avascular necrosis, both affecting ambulation and quality of life for survivors. Several risk factors for both disorders among adults have been described along with suggested interventions. However, similar recommendations for screening and management of bone abnormalities among children and adolescents post-HSCT are not clearly defined. A review of the literature using PubMed, CINAHL, National Guideline Clearinghouse, and Coc...
Source: Pain Physician - February 4, 2013 Category: Anesthesiology Authors: McDonald L, Luke J, Jude V, Chan K, Cuellar N Tags: J Pediatr Oncol Nurs Source Type: research
The knowledge, attitudes and practices of parents of children with asthma in 29 cities of China: a multi-center study
Conclusions: Generally, the parents' KAP were poor. A gap between recommended and actual practice was observed, which may be related to inadequate knowledge about and poor attitudes toward childhood asthma. Improving knowledge and attitudes may encourage better practices among parents of children with asthma.
Source: BMC Pediatrics - Latest articles - February 4, 2013 Category: Pediatrics Authors: Jing ZhaoKungling ShenLi XiangGuoqing ZhangMeng XieJuan BaiQiyi Chen Source Type: research
Striving for a zero‐error patient surgical journey through adoption of aviation‐style challenge and response flow checklists: a quality improvement project
ConclusionsWe have created a reproducible model of care involving multiple checklists at high‐risk points in the patient surgical journey. The model is reliable and has a high degree of staff engagement. It promotes patient safety by ensuring the patient, team and equipment are correctly configured at every key transition stage in the surgical journey. We have been able to achieve this with no measurable increase in turnover times or reduction in operating room efficiency.
Source: Pediatric Anesthesia - February 4, 2013 Category: Anesthesiology Authors: Daniel K. Low, Mark A. Reed, Jeremy M. Geiduschek, Lynn D. Martin Tags: Original Article Source Type: research
The correlation between T helper type 17 cells and clinical characters in Chinese paediatric patients with chronic hepatitis B
Summary Interleukin (IL)‐17‐mediated immune response has been shown to play a critical role in inflammation‐associated disease. However, its role in the pathogenesis of chronic hepatitis B virus (HBV) in paediatric patients remains unknown. We investigated the frequency of T helper type 17 (Th17) cells and evaluated the association between the Th17 and clinical characters in paediatric patients with chronic hepatitis B (CHB). The frequency of Th17 cells was detected by flow cytometry analyses from 65 paediatric patients with CHB and nine healthy controls. The degree of hepatic inflammation was graded using the histol...
Source: Clinical and Experimental Immunology - February 4, 2013 Category: Allergy & Immunology Authors: S. Zhu, H. Zhang, Y. Dong, Z. Xu, D. Chen, L. Wang, Y. Gan, F. Wang, Y. Wang, X. Xing, S. Hu, Z. Li, L. Long, L. Liu, Y. Zhong Tags: Original Article Source Type: research
Outcomes of the International Pediatric Perfusion Symposiums
Source: Artificial Organs - February 4, 2013 Category: Transplant Surgery Authors: Thomas Markmann, Akif Ündar Tags: Invited Editorial Source Type: research
International Society for Pediatric Mechanical Cardiopulmonary Support Selects Artificial Organs as Its Official Journal
Source: Artificial Organs - February 4, 2013 Category: Transplant Surgery Authors: Paul S. Malchesky, D. Eng Tags: Editorial Source Type: research
Intravenous N‐acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: A placebo‐controlled clinical trial
Conclusion: NAC did not improve 1‐year survival in non‐APAP PALF. One‐year LTx‐free survival was significantly lower with NAC, particularly among those <2 years old. These results do not support broad use of NAC in non‐APAP PALF and emphasizes the importance of conducting controlled pediatric drug trials, regardless of results in adults. (HEPATOLOGY 2012)
Source: Hepatology - February 4, 2013 Category: Internal Medicine Authors: Robert H. Squires, Anil Dhawan, Estella Alonso, Michael R. Narkewicz, Benjamin L. Shneider, Norberto Rodriguez‐Baez, Dominic Dell Olio, Saul Karpen, John Bucuvalas, Steven Lobritto, Elizabeth Rand, Philip Rosenthal, Simon Horslen, Vicky Ng, Girish Subba Tags: Liver Biology/Pathobiology Source Type: research
Secular trends and latitude gradients in sex ratios at birth in Asia over the past sixty years
ConclusionM/F is overall increasing in Asia, unlike the decline previously noted in Europe and North America. Moreover, it had been shown that there is a higher incidence of male births in southern Europe than in the north, with the opposite gradient in North America. This paper shows M/F latitude gradients in Asia are in keeping with those of Europe. The overall M/F in Asia may be rising due to improving socioeconomic conditions, and the interplay of several poorly understood factors is likely.
Source: Pediatrics International - February 4, 2013 Category: Pediatrics Authors: Grech Victor Tags: Original Article Source Type: research
Can outcomes in Duchenne muscular dystrophy be improved by public reporting of data?
Conclusions: CF longevity has increased by almost 33% from 1986 to 2010, in part due to a CF patient registry that has been stratified by individual care centers since 1999, and publically available since 2006. Implementation of outcome reporting for MDA clinics might promote a similar benefit to patients with DMD.
Source: Neurology - February 4, 2013 Category: Neurology Authors: Scully, M. A., Cwik, V. A., Marshall, B. C., Ciafaloni, E., Wolff, J. M., Getchius, T. S., Griggs, R. C. Tags: Outcome research, Muscle disease, All Pediatric, Models of care CONTEMPORARY ISSUES Source Type: research
Everolimus long-term safety and efficacy in subependymal giant cell astrocytoma
Conclusion: Everolimus therapy is safe and effective for longer term (median exposure 34.2 months) treatment of patients with TSC with SEGA. Classification of evidence: This study provides Class III evidence that everolimus, titrated to trough serum levels of 5–15 ng/mL, was effective in reducing tumor size in patients with SEGA secondary to TSC for a median of 34 months.
Source: Neurology - February 4, 2013 Category: Neurology Authors: Krueger, D. A., Care, M. M., Agricola, K., Tudor, C., Mays, M., Franz, D. N. Tags: Primary brain tumor, All Pediatric, All Epilepsy/Seizures, Other neurocutaneous disorders ARTICLE Source Type: research
Childhood obesity and risk of pediatric multiple sclerosis and clinically isolated syndrome
Conclusion: Our findings suggest the childhood obesity epidemic is likely to lead to increased morbidity from MS/CIS, particularly in adolescent girls.
Source: Neurology - February 4, 2013 Category: Neurology Authors: Langer-Gould, A., Brara, S. M., Beaber, B. E., Koebnick, C. Tags: Autonomic diseases, All Pediatric, All Demyelinating disease (CNS), Multiple sclerosis ARTICLE Source Type: research
Neonatal outcomes after preterm birth by mothers' health insurance status at birth: a retrospective cohort study
Conclusions: The underlying reasons for the lower rate of special care admissions in infants of publicly insured women compared with privately insured women despite the higher rate of low Apgar scores is yet to be determined. Future research is warranted in order to clarify the meaning of our findings for future obstetric care and whether more equitable use of paediatric services should be recommended.
Source: BMC Health Services Research - February 4, 2013 Category: Journals (General) Authors: Kristjana EinarsdóttirFatima HaggarAmanda LangridgeAnthony GunnellHelen LeonardFiona Stanley Source Type: research
Functional limitations in Romanian children with haemophilia: further testing of psychometric properties of the Paediatric Haemophilia Activities List
The objective was to gain further insight into the psychometric properties of the PedHAL and to study the functional health status of Romanian children and adolescents with haemophilia. Children attending to the rehabilitation centre of Buzias in Romania were sampled consecutively. Construct validity of the PedHAL was evaluated by concurrent testing with objective and subjective measures of physical function and functional ability. Reproducibility was tested by a 3‐day test–retest by intraclass correlation coefficient (ICC) and limits of agreement (LOA). Responsiveness to rehabilitation was assessed by Haemophilia Join...
Source: Haemophilia - February 4, 2013 Category: Hematology Authors: W. Groen, J. Net, A. M. Lacatusu, M. Serban, P. J. M. Helders, K. Fischer Tags: Original Article Source Type: research
Current practice patterns for sleep‐disordered breathing in children
ConclusionsPediatric otolaryngologists are noncompliant with the 2002 American Academy of Pediatrics and the 2011 American Academy of Otolaryngology–Head and Neck Surgery guidelines. Despite noncompliance, they fortunately have a lower threshold to monitor high‐risk children overnight following surgery. The recommended Center for Disease Control measures to diagnose childhood obesity occasionally are being utilized. An educational campaign is necessary to update clinicians who take care of children on the new evidence‐based guidelines. Level of Evidence5. Laryngoscope, 2013
Source: The Laryngoscope - February 4, 2013 Category: ENT & OMF Authors: Norman R. Friedman, Jonathan N. Perkins, Bryan McNair, Ron B. Mitchell Tags: Sleep Medicine Source Type: research
Exploring the profile of articles on traumatic dental injuries in pediatric dental journals
ConclusionsThere is an urgent need for expanding the number and quality of research on TDI in pediatric dental journals, especially with better quality study designs. Cohort studies and investigations focusing on the assessment of health services and technologies are important targets for future research.
Source: Dental Traumatology - February 4, 2013 Category: Dentistry Authors: Carlos Alberto Feldens, Paulo Floriani Kramer, Eliane Gerson Feldens Tags: Original Article Source Type: research
Effects of adenotonsillectomy on polysomnographic parameters in children with sickle cell disease
Abstract Obstructive sleep apnea (OSA) in the pediatric sickle cell disease (SCD) population can promote nightly hemoglobin oxygen desaturation, which increases the risk of central nervous system insult and may impair cognitive function. Adenotonsillectomy can ameliorate OSA symptoms, but its effect in children with SCD has not been fully investigated. We reviewed the effects of adenotonsillectomy in thirteen children with SCD by comparison of pre and post‐adenotonsillectomy polysomnography (PSG) parameters. Significant reduction in hemoglobin oxygen desaturation, decreased apnea‐hypopnea index, and increased rapid eye...
Source: Pediatric Blood and Cancer - February 4, 2013 Category: Cancer & Oncology Authors: Paul Finch, Rose Mary Stocks, Matthew P. Smeltzer, Amy Kimble, Robert Schoumacher, Jane S. Hankins Tags: Brief Report Source Type: research
Anthracycline induced cardiac toxicity in pediatric Ewing sarcoma: A longitudinal study
ConclusionsThe high incidence of cardiotoxicity associated with higher administered anthracycline dose, young age, bolus infusion, and EF decline warrants evaluation in a larger cohort. Pediatr Blood Cancer © 2013 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - February 4, 2013 Category: Cancer & Oncology Authors: Tanya Renae Brown, Chodchanok Vijarnsorn, Jim Potts, Ruth Milner, George G.S. Sandor, Christopher Fryer Tags: Research Article Source Type: research
The safety of cefepime and ceftazidime in pediatric oncology patients
ConclusionsThe use of cefepime in pediatric oncology patients is not associated with increased mortality when compared to ceftazidime, however the small number of deaths in this study limits the strength of this conclusion. Previous associations between antimicrobial therapy and increased all‐cause mortality may have been confounded by patients' demographic characteristics and co‐morbid conditions. All‐cause mortality may be an insensitive outcome for studies examining the efficacy and safety of these agents. Pediatr Blood Cancer © 2013 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - February 4, 2013 Category: Cancer & Oncology Authors: James M. Hoffman, Jamie Frediani, Michael Herr, Patricia M. Flynn, Elisabeth E. Adderson Tags: Research Article Source Type: research
Cytokine profiles in children with primary Epstein–Barr virus infection
Abstract Primary Epstein–Barr virus (EBV) infection causes infectious mononucleosis and hemophagocytic lymphohistiocytosis (HLH) in children, where EBV infects B and CD8+ T cells, respectively. We measured pro‐inflammatory and anti‐inflammatory cytokines in both diseases. Significantly higher concentrations of various mediators, including interferon‐γ, neopterin, interleukin (IL)‐6, IL‐10, IL‐18, and heme oxygenase‐1, were observed in EBV‐HLH. Because of their similarity to the profile of familial HLH, this profile was likely a consequence of HLH, but not ectopic infection. TNF‐α levels were elevated ...
Source: Pediatric Blood and Cancer - February 4, 2013 Category: Cancer & Oncology Authors: Taizo Wada, Masahiro Muraoka, Tadafumi Yokoyama, Tomoko Toma, Hirokazu Kanegane, Akihiro Yachie Tags: Brief Report Source Type: research
Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes
ConclusionsThe low overlap of dysregulated genes in AT/RTs and KRTs suggests that factors in addition to SMARCB1 loss play a role in determining subsequent gene expression. Drugs which target cell cycle or epigenetic genes may be useful in all RTs. Additionally, targeted therapies tailored to specific RT subset molecular profiles should be considered. Pediatr Blood Cancer © 2013 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - February 4, 2013 Category: Cancer & Oncology Authors: Diane K. Birks, Andrew M. Donson, Purvi R. Patel, Alexandra Sufit, Elizabeth M. Algar, Christopher Dunham, B.K. Kleinschmidt‐DeMasters, Michael H. Handler, Rajeev Vibhakar, Nicholas K. Foreman Tags: Research Article Source Type: research
Persistent defective membrane trafficking in epithelial cells of patients with familial hemophagocytic lymphohistiocytosis type 5 due to STXBP2/MUNC18‐2 mutations
ConclusionMutations in STXBP2 do not only affect cytotoxic T lymphocytes but also cause changes in the intestinal and renal epithelium resulting in severe, osmotic diarrhea and renal proximal tubular dysfunction. These defects persist after successful treatment of hemophagocytic lymphohistocytosis by HSCT. Clinical manifestations in FHL5 patients despite successful HSCT may therefore be related to defective membrane trafficking in the gut and kidney. Pediatr Blood Cancer © 2013 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - February 4, 2013 Category: Cancer & Oncology Authors: Polina Stepensky, Jack Bartram, Thomas F. Barth, Kai Lehmberg, Paul Walther, Kerstin Amann, Alan D. Philips, Ortraud Beringer, Udo Zur Stadt, Ansgar Schulz, Persis Amrolia, Michael Weintraub, Klaus‐Michael Debatin, Manfred Hoenig, Carsten Posovszky Tags: Research Article Source Type: research
Treatment of refractory hemorrhage with factor XIII in a patient with hemophilia A with inhibitor
Abstract An 11‐year‐old male with hemophilia A and a known high‐titer Factor VIII inhibitor was admitted with retroperitoneal hemorrhage. The patient was receiving infusions of recombinant activated Factor VII (rFVIIa) for a recent elbow hemorrhage when retroperitoneal bleeding commenced. Despite increased dosing of rFVIIa and a dose of activated prothrombin complex concentrate (aPCC), he continued to hemorrhage and required several blood transfusions. Factor XIII was administered 1 hour after rFVIIa and the patient demonstrated cessation of bleeding and normalization of clot strength. Factor XIII may act as an adj...
Source: Pediatric Blood and Cancer - February 4, 2013 Category: Cancer & Oncology Authors: Christopher Ng, Christopher C. Silliman, Gabrielle Pearl, Whitney Smith, Marilyn Manco‐Johnson, Michael Wang Tags: Brief Report Source Type: research
Wolff‐Parkinson‐White Syndrome and Adenosine Response in Pediatric Patients
ConclusionsIn these pediatric patients with WPW pattern on ECG, a significant minority blocked AP conduction with adenosine and this finding had 100% specificity and PPV for nonrapid baseline antegrade AP conduction. The finding of blocked AP conduction with adenosine may aid in risk stratification.
Source: Pacing and Clinical Electrophysiology : PACE - February 4, 2013 Category: Cardiology Authors: PHILIP WACKEL, LEE BEERMAN, GAURAV ARORA Tags: ORIGINAL ARTICLE Source Type: research
The Impact of Neonatal Care Resources on Regional Variation in Neonatal Mortality Among Very Low Birthweight Infants in Korea
ConclusionsRegional disparity in mortality of VLBW infants in Korea is most marked in the lowest‐birthweight group, <750 g. This disparity is primarily due to lack of resources for neonatal intensive care in most of provincial areas.
Source: Paediatric and Perinatal Epidemiology - February 4, 2013 Category: Perinatology & Neonatology Authors: Jae Won Shim, Myo Jing Kim, Ee‐Kyung Kim, Hyun Kyung Park, Eun Song Song, Soon Min Lee, Jang Hoon Lee, Hyun‐Seung Jin, Eun Sun Kim, Yun Sil Chang, Tags: Neonatal Care Source Type: research
Association Between Transient Hypothyroxinaemia of Prematurity and Adult Autism Spectrum Disorder in a Low‐Birthweight Cohort: An Exploratory Study
ConclusionWhile the primary relation between THOP and ASD found here is not statistically significant, the magnitude of association and significant relationship observed in the subgroup whose mothers did not have hypertension during pregnancy suggest that it is worthy of further investigation.
Source: Paediatric and Perinatal Epidemiology - February 4, 2013 Category: Perinatology & Neonatology Authors: Steven J. Korzeniewski, Jennifer A. Pinto‐Martin, Agnes H. Whitaker, Judith F. Feldman, John M. Lorenz, Susan E. Levy, Tammy Z. Movsas, Athina Pappas, Nigel Paneth Tags: Short and Long‐term Infant Outcomes Source Type: research
Risk Factors for Acute Respiratory Morbidity in Moderately Preterm Infants
ConclusionWe conclude that acute respiratory morbidity in moderately preterm infants is common and predicted by multiparity, caesarean section, low Apgar score and male sex.
Source: Paediatric and Perinatal Epidemiology - February 4, 2013 Category: Perinatology & Neonatology Authors: Maria Altman, Mireille Vanpée, Sven Cnattingius, Mikael Norman Tags: Short and Long‐term Infant Outcomes Source Type: research
Clustering of Neonatal Deaths in Bangladesh: Results From the Projahnmo Studies
ConclusionThe preceding sibling's outcome may be a surrogate for genetic and other maternal health factors such as nutrition, infection or environmental factors that were not measured within Projahnmo. Further research into these factors is required in order to explain the variation in the risk for NM.
Source: Paediatric and Perinatal Epidemiology - February 4, 2013 Category: Perinatology & Neonatology Authors: Bareng A. S. Nonyane, Emma K. Williams, Carla Blauvelt, Mohammad R. Shah, Gary L. Darmstadt, Lawrence Moulton, Abdullah H. Baqui Tags: Infant Health: Mortality Source Type: research
An Algorithm for the Estimation of Gestational Age at the Time of Fetal Death
ConclusionsPrecise assignment of GA at death, defined as reliable dating criteria and a short interval (≤1 week) during which fetal death was known to have occurred, was possible in 46.6% of cases. Fetal foot length is a relatively accurate measure of GA at death and should be collected in all stillbirth cases.
Source: Paediatric and Perinatal Epidemiology - February 4, 2013 Category: Perinatology & Neonatology Authors: Deborah L. Conway, Nellie I. Hansen, Donald J. Dudley, Corette B. Parker, Uma M. Reddy, Robert M. Silver, Radek Bukowski, Halit Pinar, Barbara J. Stoll, Michael W. Varner, George R. Saade, Carol Hogue, Marian Willinger, Donald Coustan, Matthew A. Koch, Ro Tags: Infant Health: Mortality Source Type: research
A Test of Agreement of Customised Birthweight Models
ConclusionAll published CBMs demonstrated ability to predict birthweight with reasonable accuracy. The effects of maternal and fetal characteristics on birthweight appear to be consistent across birthweight models. This finding is a further step in validating the CBM, and provides greater evidence for the creation of a global model.
Source: Paediatric and Perinatal Epidemiology - February 4, 2013 Category: Perinatology & Neonatology Authors: Kristen S. Gibbons, Allan M. Z. Chang, Vicki J. Flenady, Kassam Mahomed, Peter H. Gray, Glenn J. Gardener, Dominique Rossouw Tags: Birthweight Source Type: research
Differences in Birthweight Curves Between Newborns of Immigrant Mothers vs. Infants Born in Their Corresponding Native Countries: Systematic Overview
ConclusionsTerm birthweight percentiles are typically higher among term infants born to mother who immigrate to Canada than those of infants born in their respective native country.
Source: Paediatric and Perinatal Epidemiology - February 4, 2013 Category: Perinatology & Neonatology Authors: Talia Boshari, Marcelo L. Urquia, Michael Sgro, Leanne R. De Souza, Joel G. Ray Tags: Birthweight Source Type: research
Characteristics in the First Vaginal Birth and Their Association with Mode of Delivery in the Subsequent Birth
ConclusionsObstetrical interventions and adverse pregnancy outcomes in the first birth were associated with increased risk of operative delivery in the second birth.
Source: Paediatric and Perinatal Epidemiology - February 4, 2013 Category: Perinatology & Neonatology Authors: Jian Sheng Chen, Jane B. Ford, Amanda Ampt, Judy M. Simpson, Christine L. Roberts Tags: Mode of Delivery Source Type: research
Health-Related Quality of Life and Cognitive Functioning at On- and Off-Treatment Periods in Children Aged between 6-13 Years Old with Brain Tumors: A Prospective Longitudinal Study.
Conclusion: The cognitive ability and intelligence level of the patients significantly declined between on and off treatment periods, and higher intelligence functioning at both on and off treatment was correlated with long-term higher HRQOL. Further investigations that monitor intelligence, HRQOL and parenting stress over a longer period, using a greater number of participants, are needed. PMID: 23364961 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: An KJ, Joung YS, Sung KW, Kim JH Tags: Yonsei Med J Source Type: research
[New tool for drug dosing in life-threatening pediatric emergencies.]
PMID: 23377370 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - February 3, 2013 Category: Anesthesiology Authors: Zugck TO Tags: Anaesthesist Source Type: research
Pediatric allergy and immunology in Israel
Abstract After the geographic and sociodemographic settings as well as the health care in Israel are briefly described, the scope of pediatric allergy and immunology in Israel is presented. This includes specific disorders commonly encountered, the environment that induces symptoms, the specialists who treat them, and the common challenges of patients, parents, doctors, and allied health personnel who collaborate to manage the maladies and patient care. Allergies usually affect some overall 15–20% of the pediatric population. The main allergens are inhaled, ingested, or injected (insects stings). Generally, the incidence...
Source: Pediatric Allergy and Immunology - February 3, 2013 Category: Allergy & Immunology Authors: Carmi Geller‐Bernstein, Amos Etzioni Tags: Original Article Source Type: research
Prednisolone reduces recurrent wheezing after first rhinovirus wheeze: a 7‐year follow‐up
ConclusionsOur data strengthen the role of rhinovirus‐associated wheeze as an important risk factor for recurrent wheezing and asthma in young first‐time wheezing children. Prospective randomized trials on the efficacy of corticosteroids in rhinovirus‐associated early wheezing are warranted. (ClinicalTrials.gov number, NCT 00494624)
Source: Pediatric Allergy and Immunology - February 3, 2013 Category: Allergy & Immunology Authors: Minna Lukkarinen, Heikki Lukkarinen, Pasi Lehtinen, Tytti Vuorinen, Olli Ruuskanen, Tuomas Jartti Tags: Original Article Source Type: research
Prevalence of confirmed immediate type drug hypersensitivity reactions among school children
ConclusionOur results suggest that a positive clinical history is not enough to make a diagnosis of drug allergy, which highlights the significance of undertaking further diagnostic evaluation.
Source: Pediatric Allergy and Immunology - February 3, 2013 Category: Allergy & Immunology Authors: Mustafa Erkoçoğlu, Aysenur Kaya, Ersoy Civelek, Celal Özcan, Banu Çakır, Aysegül Akan, Müge Toyran, Tayfur Ginis, Can Naci Kocabas Tags: Original Article Source Type: research
Allergic contact dermatitis in children: which factors are relevant? (review of the literature)
Abstract Allergic Contact Dermatitis (ACD) in children is increasing. Sensitization to contact allergens can start in early infancy. The epidermal barrier is crucial for the development of sensitization and elicitation of ACD. Factors that may influence the onset of sensitization in children are atopic dermatitis, skin barrier defects and intense or repetitive contact with allergens. Topical treatment of ACD is associated with cutaneous sensitization, although the prevalence is not high. ACD because of haptens in shoes or shin guards should be considered in cases of persistent foot eruptions or sharply defined dermatitis o...
Source: Pediatric Allergy and Immunology - February 3, 2013 Category: Allergy & Immunology Authors: Flora B. Waard‐van der Spek, Klaus E. Andersen, Ulf Darsow, Charlotte G. Mortz, David Orton, Margitta Worm, Antonella Muraro, Peter Schmid‐Grendelmeier, Ramon Grimalt, Radoslaw Spiewak, Odilija Rudzeviciene, Carsten Flohr, Susanne Halken, Alessandro F Tags: Review Article Source Type: research
Standardized treatment planning methodology for passively scattered proton craniospinal irradiation
Conclusions: This study described and evaluated a standardized method for proton treatment planning for CSI. Overall, the standardized planning methodology yielded consistently high quality treatment plans and perhaps most importantly, it did so for an anatomically diverse patient population.
Source: Radiation Oncology - February 3, 2013 Category: Cancer & Oncology Authors: Annelise GiebelerWayne NewhauserRichard AmosAnita MahajanKenneth HomannRebecca Howell Source Type: research