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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 3.

STI Rates Increase Among Mississippi Teensemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Teenagers ages 15 through 19 now comprise nearly 40% of Mississippi's sexually transmitted infection cases, the Jackson Clarion-Ledger reports. The number of chlamydia cases among teens increased 25% over the last five years, and numbers of cases in 2008 were close to the 2007 total.
Source: Pediatrics News From Medical News Today - November 18, 2009 Category: Pediatrics Tags: Sexual Health / STDs Source Type: news

Health, Policy Experts Gather For 3-Day Conference On Family Planningemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
By offering family planning services to people seeking HIV/AIDS information and treatment, Africa's population growth rate could be curbed by 2.5 percent, health experts said Monday during an international family health conference in Kampala, Uganda, Agence France-Presse reports (11/16).
Source: Pediatrics News From Medical News Today - November 18, 2009 Category: Pediatrics Tags: Sexual Health / STDs Source Type: news

Studies Suggest Parental Monitoring Can Help Decrease Adolescent Marijuana Useemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Marijuana is the most widely used illicit drug by adolescents, with almost 42% of high school seniors admitting to having experimented with it. Continued marijuana use may result in a number of serious consequences including depression, cognitive impairment, cardiovascular disease, and certain forms of cancer. As such, it is critical to prevent marijuana use by adolescents and numerous behavioral and medical scientists have been trying to establish the best means of prevention.
Source: Pediatrics News From Medical News Today - November 18, 2009 Category: Pediatrics Tags: Alcohol / Addiction / Illegal Drugs Source Type: news

New presenting symptoms of Chiari I malformation: report of two casesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions  These case reports can suggest the association of hemihypertrophy and claw hand with Chiari I malformation and syringomyelia. Further studies are necessary to assess the real incidence of focal motor deficits and mesodermic disorders in Chiari I malformation in order to clarify their pathogenetical mechanisms. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00381-009-1043-zAuthors Benedetta Ludovica Pettorini, Birmingham Children’s Hospital Paediatric Neurosurgery Birmingham UKChenur Oesman, Birmingham Children’s Hospital Paediatric Neurosurgery Birmingham UKShailendra Mag...
Source: Child's Nervous System - November 18, 2009 Category: Pediatrics Tags: Child's Nervous System Source Type: journals

Tween: Child Developmentemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Tween: Child DevelopmentCategory: Health and LivingCreated: 11/18/2009 10:41:00 AMLast Editorial Review: 11/18/2009 10:41:12 AM
Source: MedicineNet Kids Health General - November 18, 2009 Category: Pediatrics Source Type: consumer

Folic Acid, B12 May Increase Cancer Riskemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Folic Acid, B12 May Increase Cancer RiskCategory: Health NewsCreated: 11/18/2009 9:39:00 AMLast Editorial Review: 11/18/2009 9:39:21 AM
Source: MedicineNet Kids Health General - November 18, 2009 Category: Pediatrics Source Type: consumer

Viagra Helpful for Children With Heart Defectemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Viagra Helpful for Children With Heart DefectCategory: Health NewsCreated: 11/17/2009 4:10:00 PMLast Editorial Review: 11/18/2009
Source: MedicineNet Kids Health General - November 18, 2009 Category: Pediatrics Source Type: consumer

Cytokine levels in neonatal necrotizing enterocolitis and long-term growth and neurodevelopmentemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: This study suggests that increased serum levels of pro-inflammatory cytokines may play a role in the poor growth and neurodevelopment associated with this high-risk population.
Source: Acta Paediatrica - November 18, 2009 Category: Pediatrics Authors: A Lodha, E Asztalos, AM Moore Source Type: journals

Correlation between 6-min walk test and exercise stress test in healthy childrenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: SMWT distance is significantly correlated with the eVO2 obtained during the EST. This indicates that SMWT is also one of the predictive markers for EST performance.
Source: Acta Paediatrica - November 18, 2009 Category: Pediatrics Authors: A Limsuwan, R Wongwandee, P Khowsathit Source Type: journals

Most common allergic march sequences identifiedemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
There are numerous variants of the “allergic march,” with eczema followed by asthma and then rhinitis being the most common sequence, say UK researchers.
Source: MedWire News - Pediatrics - November 18, 2009 Category: Pediatrics Source Type: news

High-dose Folic Acid and B12 May Hike Cancer Risk (CME/CE)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
High-dose folic acid and vitamin B12 supplements were associated with an increased incidence of cancer (MedPage Today) -- particularly lung cancer -- in a post-hoc analysis of two Norwegian trials.
Source: MedPage Today Pediatrics - November 17, 2009 Category: Pediatrics Source Type: news

Uninsured trauma victims more likely to die of their injuriesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Research from Children’s Hospital Boston’s Heather Rosen, MD, MPH, finds that people who are admitted to the hospital for trauma are more likely to die from their injuries if they don’t have health insurance than if they do. In this WBUR report, Rosen offers some possible explanations for the alarming disparity. Her research was also reported on by the Associated Press. Related posts:Health headlines: Premature babies, burn injuries and cherry flavored TamifluGlass-table injuries to children prompts industry changesConcussion injuries in youth athletes
Source: Thrive, Children's Hospital Boston - November 17, 2009 Category: Pediatrics Authors: Erin Graham Tags: All posts health disparities trauma and children trauma injury and health care Source Type: organizations

A New Normal for Cancer Survivorsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Learn how Duke is changing care to meet the needs of an exploding patient population -- cancer survivors
Source: DukeHealth.org: Duke Health Features - November 17, 2009 Category: Pediatrics Tags: Cancer Patient Support Cancer Services Source Type: organizations

More and more teens infected with STDsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The CDC just released its annual report on sexually transmitted diseases and the results for teens are pretty disturbing. Although 15- to 24-year-olds represent only 25% of the sexually experienced population, they acquire nearly half of all new STDs. The report notes that sexually active teens are at a higher risk of contracting an STD because of a combination of behavioral, biological and cultural reasons. Barriers to accessing quality STD prevention services– like lack of insurance and transportation, or concerns about confidentiality, may also play a big role, the study concludes. It’s well known that alco...
Source: Thrive, Children's Hospital Boston - November 17, 2009 Category: Pediatrics Authors: Kristin Cantu Tags: All posts Research at Children's alcohol Center for Disease Control drugs sex education sexually transmitted disease STD teen health teenagers Source Type: organizations

Boys, Twins And Firstborn Babies More Likely To Have Flat Spotsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Since the American Academy of Pediatrics recommended in 1992 that all infants sleep on their back to reduce the risk of Sudden Infant Death Syndrome, pediatricians have seen an increased number of infants who develop flat spots on the back of their head - a condition called deformational plagiocephaly (DP). In a study, "Risk Factors Associated With Deformational Plagiocephaly," published in the December issue of Pediatrics (appearing online Nov.
Source: Pediatrics News From Medical News Today - November 17, 2009 Category: Pediatrics Tags: Pediatrics / Children's Health Source Type: news

Exergen TemporalScanner Effective In Detecting Fevers In Children Aged 1 - 4 Years, Study Findsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
"Temporal artery thermometry is an effective screening tool in identifying fever in children one to four years of age," according to a recent study published in the journal Clinical Pediatrics. The study investigated the sensitivity and specificity of scanning the forehead area to detect temporal artery temperature, as a substitute for rectal temperatures in children 1-4 years old.
Source: Pediatrics News From Medical News Today - November 17, 2009 Category: Pediatrics Tags: Pediatrics / Children's Health Source Type: news

Psychologists Welcome Tobacco Curbs In New Health Actemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The British Psychological Society welcomes the passage of measures protecting young people from harm caused by tobacco into law in the Health Act 2009. The President of the Society, Sue Gardner, says: "We regard the protection of children and young people from smoking as an extremely high priority. All the available evidence suggests that the earlier young people start to smoke the more difficult they will find it to quit.
Source: Pediatrics News From Medical News Today - November 17, 2009 Category: Pediatrics Tags: Smoking / Quit Smoking Source Type: news

FDA Expands Use Of CSL Limited's Seasonal And H1N1 Vaccines To Infants And Childrenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The U.S. Food and Drug Administration has approved the use of the CSL Limited's seasonal and 2009 H1N1 influenza vaccines to include children ages 6 months and older. These vaccine were previously approved for use in adults, ages 18 years and older "Because children are among those most vulnerable to the 2009 H1N1 virus, having a broader range of vaccines available for use in children is an important step in responding to the H1N1 outbreak," said Margaret A. Hamburg, M.D.
Source: Pediatrics News From Medical News Today - November 17, 2009 Category: Pediatrics Tags: Swine Flu Source Type: news

Young Children: Child Developmentemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Young Children: Child DevelopmentCategory: Health and LivingCreated: 11/17/2009 3:25:00 PMLast Editorial Review: 11/17/2009 3:25:05 PM
Source: MedicineNet Kids Health General - November 17, 2009 Category: Pediatrics Source Type: consumer

'Fearless' 3-Year-Olds Might Be Tomorrow's Criminalsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: 'Fearless' 3-Year-Olds Might Be Tomorrow's CriminalsCategory: Health NewsCreated: 11/17/2009 8:10:00 AMLast Editorial Review: 11/17/2009
Source: MedicineNet Kids Health General - November 17, 2009 Category: Pediatrics Source Type: consumer

A stump appendicitis in a child: a case reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Stump appendicitis is rare and should be considered in any patient with right lower quadrant pain even if there is a history of appendectomy. Complete removal of the appendix is the only mean to prevent the occurrence of this complication.
Source: Italian Journal of Pediatrics - November 17, 2009 Category: Pediatrics Authors: Manef GasmiFatma FitouriSondes SahliRadhia JemaiMourad Hamzaoui Source Type: journals

CKS topic review: Teethingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: No information given Area: Evidence > Guidelines This Topic Review from the Clinical Knowledge Service (CKS) covers the management of teething in infants under 3 years.
Source: NeLM - Paediatrics - November 17, 2009 Category: Pediatrics Source Type: organizations

Birth weight deviation and early postnatal growth are related to optic nerve morphology at school age in children born very preterm.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The aim of this study was to evaluate the influence of early and later postnatal growth variables on optic disc morphology in children (n=53) born at gestational age (GA) <32 weeks. On fundus photographs taken at a median age of 5.4 years the optic discs were evaluated using digital image analysis, and compared with those of a control group (n=203). The results were analyzed in relation to GA, birth weight (BW) standard deviation score (SDS), insulin-like growth factor 1 (IGF-1), weight at postmenstrual age 32 weeks (SDS), and weight, length and head circumference (SDS) at follow-up. The preterm children's optic dis...
Source: Pediatric Research - November 17, 2009 Category: Pediatrics Authors: Wikstrand MH, Hård AL, Niklasson A, Hellström A Tags: Pediatr Res Source Type: journals

Severe gastrointestinal bleeding and thrombocytopenia in a child with an anti-GATA1 autoantibody.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, this study is the first report of an anti-GATA1 autoantibody leading to severe thrombocytopenia and gastrointestinal bleeding from multiple pinpoint hemangiomata. PMID: 19924028 [PubMed - as supplied by publisher]
Source: Pediatric Research - November 17, 2009 Category: Pediatrics Authors: Waele LD, Freson K, Louwette S, Thys C, Wittevrongel C, Vos RD, Debeer A, Geet CV Tags: Pediatr Res Source Type: journals

Should babies watch videos or tv?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
You may have heard the recent controversy about “Baby Einstein” videos. Originally touted as educational products for babies, in 2006 the Disney Company stopped marketing the videos as educational. This was due to studies coming out showing that infants and toddlers exposed to daily doses of television has a propensity to develop attention disorders by age 7. Attention disorders include ADHD and ADD, which affects a child’s ability to focus, their attention span, leading them to have learning and behavior disorders.Of concern is children’s perception of events they see on television. When they see violence, do they...
Source: Pediatric Health Associates - November 16, 2009 Category: Pediatrics Tags: Recalls Source Type: organizations

Robots in the ORemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Learn how robots are changing the face of surgery.
Source: DukeHealth.org: Duke Health Features - November 16, 2009 Category: Pediatrics Tags: Robotic Surgery Source Type: organizations

Rationing Health Care: Why We Shouldn't Always Get What We Needemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Bioethicist Gopal Sreenivasan, PhD, asserts that a seemingly severe approach to health care reform -- rationing -- is not only part of a workable solution, but a moral duty.
Source: DukeHealth.org: Duke Health Features - November 16, 2009 Category: Pediatrics Tags: Other Source Type: organizations

One son’s story: Getting to know my father thanks to advances in epilepsy medicationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Steve Coldwell and his father, Stephen, in 1974 When I think of my father’s epilepsy, I always go back to a seizure he had during one of my Boy Scout camping trips. It wasn’t the first time I saw my dad have an epileptic seizure, but it was the first time I was the only member of our family around to deal with it. We were playing softball and he was at bat. After a pitch or two went past him, he simply let the bat fall to the ground and sat down on home plate. I immediately knew he was having a seizure, so I helped him up, walked him off the field and talked to him until he came back around. When my mother heard about...
Source: Thrive, Children's Hospital Boston - November 16, 2009 Category: Pediatrics Authors: Steve Coldwell Tags: All posts epilepsy Source Type: organizations

Replyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
To the Editor: We appreciate the interest of Ting and Cheung in our report of similar cerebral blood flow velocities in extremely low birth weight (ELBW) infants with and without hypotension (before treatment). We, too, feel that our case-control study provides valuable information to the literature and hope it will aid in the design of a large scale, multi-center trial evaluating the treatment of hypotension (including permissive hypotension) in ELBW infants. As addressed in their letter, it was previously reported that cerebral blood flow (CBF) was reduced in ELBW infants with hypotension. However, the 12 infants with h...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Jeffrey R. Kaiser, Marla H. Lightburn Tags: Letters to the Editor Source Type: journals

Nasal continuous positive airway pressure devices: Separating science from religionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
To the Editor: We read with great interest the article by Gupta et al comparing bubble continuous positive airway pressure (BCPAP) with Infant Flow Driver CPAP (IFD-CPAP), along with the accompanying editorial by Polin. It is commendable that neonatologists are actively investigating different methods of delivering CPAP, a therapy that we use with regularity. Although the authors found no significant differences between the 2 devices in terms of the primary outcome of extubation failure rate within 72 hours, given what we know about the devices, we are surprised by the large difference in extubation success rates favoring...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Doron J. Kahn, Sherry E. Courtney Tags: Letters to the Editor Source Type: journals

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To the Editor: We thank Kahn and Courtney for their comments. As they note, some studies, including their own, have compared the physiological effects of “continuous flow” with “variable flow” CPAP and shown advantages of the variable flow system. The clinical outcome of interest, however, can only be judged when the devices are used in vivo, and any conclusions of superiority can only be made after studying the safety and long-term outcomes data in human subjects. For instance, despite the stated putative advantages, a large randomized controlled trial comparing “variable flow” CPAP and “continuous flow” ...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Sunil K. Sinha, Samir Gupta, Win Tin, Steven M. Donn Tags: Letters to the Editor Source Type: journals

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To the Editor: Kahn and Courtney have written a Letter to the Editor in response to the recent publication of Gupta et al (and my accompanying editorial) comparing CPAP delivered by Infant Flow Driver with a Bubble CPAP device. The letter raises a few issues pertinent to the debate about the best way to deliver CPAP.
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Richard A. Polin Tags: Letters to the Editor Source Type: journals

Neoplasia in Familial Dysautonomia: A 20-Year Review in a Young Patient Populationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We reviewed the charts of all patients with familial dysautonomia (n = 631) and found that 2% had been diagnosed with tumors. We hypothesize that the IκB Kinase-associated protein gene mutation, which causes aberrant RNA splicing in patients with familial dysautonomia, may contribute to tumorigenesis in this genetically homogenous patient population.
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Gabrielle Gold-von Simson, Eleny Romanos-Sirakis, Channa Maayan, Felicia B. Axelrod Tags: Clinical and Laboratory Observations Source Type: journals

Hepatoblastoma in a Patient with Sotos Syndromeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report a case of hepatoblastoma that developed in a child with Sotos syndrome, an overgrowth syndrome with an increased risk of neoplasms. Genome-wide analysis of copy number alterations showed a gain of chromosome 2, uniparental disomy of 18q, and microdeletion of 5q35.
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Motohiro Kato, Junko Takita, Kan Takahashi, Masakazu Mimaki, Yuyan Chen, Katsuyoshi Koh, Kohmei Ida, Akira Oka, Masashi Mizuguchi, Seishi Ogawa, Takashi Igarashi Tags: Clinical and Laboratory Observations Source Type: journals

Effective Desensitization to Imiglucerase in a Patient with Type I Gaucher Diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We describe a child who had anaphylactic hypersensitivity to imiglucerase therapy for Gaucher disease. Treatment was stopped and symptoms returned. After immune desensitization to imiglucerase using a rush protocol, the patient was able to resume treatment and has not had further hypersensitivity complications to date.
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Diego G. Peroni, Lydia Pescollderungg, Giorgio L. Piacentini, Walburga Cassar, Attilio L. Boner Tags: Clinical and Laboratory Observations Source Type: journals

An Unusual Case of Cardiomegalyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
An otherwise healthy 9-year-old boy with a history of asthma was referred to our institution secondary to cardiomegaly observed on a chest radiograph. His history was significant for several weeks of intermittent epigastric pain, 2 days of fever, and mild shortness of breath. Results of his physical examination, routine laboratory data, and electrocardiogram (; available at www.jpeds.com) were within normal limits. His chest radiograph demonstrated severe cardiomegaly and left-sided basilar streaky opacities ().
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Amanda L. Cook, Derek A. Williams, Milan Nadkarni Tags: Insights Source Type: journals

Unrecognized Invasive Infection in a Neonate Colonized with Methicillin-Resistant Staphylococcus aureusemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A 3-month-old, 26-week premature infant presented to a regional hospital with macrocephaly. Head computed tomography revealed abnormal brain with limited cortical tissue, ventriculomegaly, and ring-enhancing foci, prompting referral to our center. Magnetic resonance imaging confirmed extensive cerebral abscesses ().
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Rebecca S. Woodlief, Jonathan E. Markowitz Tags: Insights Source Type: journals

Cerebral blood flow velocities in extremely low birth weight infantsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
To the Editor: We read with great interest the article of Lightburn et al, which reported similar cerebral blood flow (CBF) velocities of extremely low birth weight (ELBW) infants with and without hypotension. The relationship between low early postnatal CBF and subsequent neurodisability is always the concern of clinicians. Hypotension in ELBW infants during the first postnatal day is not uncommon and may be caused by delayed adaptation of the immature myocardium, the sudden increase in systemic vascular resistance, and/or vasodilatation related to chorioamnionitis and funisitis. Munro et al reported that CBF was reduce...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Joseph Y. Ting, Po-Yin Cheung Tags: Letters to the Editor Source Type: journals

The Importance of Sweat Testing for Older Siblings of Patients with Cystic Fibrosis Identified by Newborn Screeningemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report cystic fibrosis (CF) care center instructions for sweat testing in older siblings after implementation of the French nationwide newborn screening program, and we evaluate the incidence of unrecognized CF. Nearly 9% of families with an infant screened for CF were unaware of an affected older sibling. We strongly recommend sweat testing for all first-degree older children.
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Anne Munck, Elise Houssin, Michel Roussey Tags: Clinical and Laboratory Observations Source Type: journals

Pachydermatodactyly Mimics Polyarticular Juvenile Idiopathic Arthritisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report 2 cases erroneously diagnosed as polyarticular juvenile idiopathic arthritis, then referred to pediatric rheumatology for further assessment because of lack of improvement after initial treatment.
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Basil M. Fathalla, Donald P. Goldsmith Tags: Clinical and Laboratory Observations Source Type: journals

Asymptomatic Maternal Combined Homocystinuria and Methylmalonic Aciduria (cblC) Detected through Low Carnitine Levels on Newborn Screeningemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A symptom-free woman gave birth to a girl with a low carnitine level on newborn screening. The baby was unaffected, but the mother had biochemical abnormalities and mutations characteristic of the cblC defect of vitamin B12 metabolism (late-onset form). This patient with cblC was detected through her infant's newborn screening.
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Henry J. Lin, Julie A. Neidich, Denise Salazar, Evangela Thomas-Johnson, Barbara F. Ferreira, Alan M. Kwong, Amy M. Lin, Adam J. Jonas, Steven Levine, Fred Lorey, David S. Rosenblatt Tags: Clinical and Laboratory Observations Source Type: journals

Inflaming the Debate on Infant Colicemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Research in infant colic is beleaguered in its progress toward etiology and subsequent targeted therapy by the lack of a precise definition, relying on pattern recognition from the history, which is usually provided by the infant's mother. Consequently, little reliable and reproducible epidemiology has been generated due to the inevitable variability in reported frequency of the disorder. A systematic review of the frequency of infant colic in community-based prospective and retrospective studies found that the incidence of infant colic ranged widely, from 3% to 40%. Even with the authors selecting studies with the perhaps...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: David J. Moore Tags: Editorials Source Type: journals

Treatment of the Patent Ductus Arteriosus: When, How, and for How Long?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In the vast majority of neonates, both term and preterm, the decrease in pulmonary vascular resistance after birth reverses the direction of the shunt flow through the ductus arteriosus to primarily left to right. In healthy term neonates, the ductus then closes within the first 2 to 3 postnatal days, but the shunt persists in most of the very preterm infants (≤28 weeks). With the lungs becoming the organ of gas exchange after birth, the systemic and pulmonary circulations separate and the cardiovascular system functions as a circulation in series. Under these circumstances there are no hemodynamic benefits of shunts bet...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Shahab Noori, Istvan Seri Tags: Editorials Source Type: journals

Update on “The Choking Game”email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This report summarizes the current understanding of a risk-taking behavior by older children and young adolescents. Asphyxial games, often referred to as “the choking game” by the media and in the medical literature, are now a recognized thrill-seeking behavior among young people. Recent reports indicate that knowledge of and participation in such activities is more common than previously recognized by most adults, and that death can occur, particularly when the activity is solitary in nature. Most pediatricians recognize that the behavior itself is not new, but there are critical differences in how this “game” is ...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Thomas A. Andrew, Andrew Macnab, Patricia Russell Tags: Medical Progress Source Type: journals

The choking gameemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
refers to risk taking behavior by older children and adolescents that involve asphyxia; the name “The Choking Game” has appeared in the media and the medical literature. In this issue of The Journal, Andrew et al present a Medical Progress article concerning this disturbing epidemic.
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Robert W. Wilmott Tags: The Editors' Perspectives Source Type: journals

Pediatric sudden deathemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Sudden death is often thought of as an adult phenomenon, usually the result of cardiovascular disease. However, sudden death does occur in the pediatric age range and may have a variety of causes. Unfortunately, there are fewer population-based data than optimum on this subject. In this issue of The Journal, Wu et al report on a population-based study of pediatric sudden death in Taiwan. They used a National Health Insurance database, and they found that the incidence of sudden death for individuals age 1-18 years was 2.7 / 100 000 person years. Incidence rates reached a peak in infancy, then declined and reached a nadir a...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Stephen R. Daniels Tags: The Editors' Perspectives Source Type: journals

Early child care exposure and risk of childhood asthmaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Gurka et al from the University of Virginia recently completed a study of 939 children and their families enrolled in the National Institute of Child Health and Development Study of Early Child Care and Youth Development. They assessed risk factors for persistent or late onset asthma by 15 years of age and found that the number of children in the child care environment when the child was a toddler was significantly associated with the odds of asthma, even after adjusting for respiratory illnesses and other risk factors. The fewer the children exposed to as toddlers, the higher of the probability of persistent or late onset...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Robert W. Wilmott Tags: The Editors' Perspectives Source Type: journals

“Simple dimples” and deviated gluteal foldsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Pediatricians have been comfortable with assessing as insignificant the common low-lying midline dimple or deviated gluteal folds found at the nursery or first well-infant examination. The current prospective study from Tel Aviv assessed 254 infants less than 6 months of age who were referred for neurosurgical consultation; 154 had these isolated, low-risk skin findings – “simple dimple” (ie, midline, within 2.5 cm of the anus, and with no other abnormality) or deviated gluteal folds (ie, abnormal folds whether bifid, split symmetrically, or asymmetrically without a mass). Of 151 ultrasound examinations performed on ...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Sarah S. Long Tags: The Editors' Perspectives Source Type: journals

Changing providers is associated with poor asthma controlemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this issue of The Journal, Dombkowski et al from the University of Michigan have studied the relationship between continuity of medical providers and exacerbations of asthma. The results showed that children with multiple prescribers in different practices had an increased risk of requiring a visit to the emergency room; this relationship was true for those with both high and those with low prescription frequency. The results suggest that relative disorganization of care is associated with poor asthma control. They also show that providers may not be able to identify high risk patients based simply on the number of pres...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Robert W. Wilmott Tags: The Editors' Perspectives Source Type: journals

Pulmonary vasodilation with sildenafil in newbornsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Although inhaled nitric oxide (iNO) is widely used for pulmonary hypertension from multiple causes in newborns, not all patients respond. The iNO works as a vasodilator by increasing cGMP in pulmonary vascular smooth muscle. There are other ways to increase cGMP levels, and one is to prevent degradation of cGMP by inhibition of the type 5 phosphodiesterase in the lung with sildenafil. This drug is available as a pill but not as an intravenous preparation. In this issue of The Journal, Steinhorn et al report a multicenter dose range study of intravenous sildenafil for infants with severe pulmonary hypertension. The infants ...
Source: The Journal of Pediatrics - November 16, 2009 Category: Pediatrics Authors: Alan H. Jobe Tags: The Editors' Perspectives Source Type: journals