Perinatology & Neonatology
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A possible association of periodontal infectious diseases in pregnant women with isolated orofacial clefts in their children: A population-based case-control study
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The aim of the study was to check the association of maternal periodontal infectious disease (MPID) during pregnancy and the possible risk for birth outcomes, mainly structural birth defects: congenital abnormalities (CAs) in their children.The population-based data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities, 1980-1996, was evaluated. The occurrence of medically recorded MPID in the prenatal maternity logbook was compared in 22,843 cases with different CAs and 38,151 matched controls without defects.Twenty-one case mothers who had offspring with a CA (case group) and 17 pregnant women...
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 20, 2010 Category: Perinatology & Neonatology Authors: Ferenc Bánhidy, Nándor Ács, Erzsébet H. Puhó, Andrew E. Czeizel Source Type: journals
Elevated glucose induces congenital heart defects by altering the expression of tbx5, tbx20, and has2 in developing zebrafish embryos
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Maternal diabetes increases the risk of congenital heart defects in infants, and hyperglycemia acts as a major teratogen. Multiple steps of cardiac development, including endocardial cushion morphogenesis and development of neural crest cells, are challenged under elevated glucose conditions. However, the direct effect of hyperglycemia on embryo heart organogenesis remains to be investigated.Zebrafish embryos in different stages were exposed to D-glucose for 12 or 24 hr to determine the sensitive window during early heart development. In the subsequent study, 6 hr post-fertilization embryos were treated with either 25 mmol...
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 19, 2010 Category: Perinatology & Neonatology Authors: Jintao Liang, Yonghao Gui, Wei Wang, Shan Gao, Jing Li, Houyan Song Source Type: journals
Human embryogenesis review
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No abstract. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 19, 2010 Category: Perinatology & Neonatology Authors: Armand Lione Source Type: journals
A new methodology to preserve the original proportion and integrity of cell-free fetal DNA in maternal plasma during sample processing and storage
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To develop a standardized blood collection device that preserves fetal cell-free DNA and minimizes the cell-free DNA background in maternal plasma.Blood samples were drawn from healthy pregnant donors into K3EDTA (BD vacutainer®) and Cell-free DNATM BCT tubes (Streck®, Inc.) and kept at ambient temperature. Plasma was separated by centrifugation and cell-free DNA was extracted. Cell-free DNA from plasma was quantified by quantitative real-time polymerase chain reaction.Blood drawn into Cell-free DNATM BCT tubes showed no change in the original proportion of fetal cell-free DNA during a 14-day storage period at ambient te...
Source: Prenatal Diagnosis - March 19, 2010 Category: Perinatology & Neonatology Authors: M. R. Fernando, K. Chen, S. Norton, G. Krzyzanowski, D. Bourne, B. Hunsley, W. L. Ryan, C. Bassett Source Type: journals
Prenatal diagnosis of autosomal dominant hereditary spastic paraplegia (SPG42) caused by SLC33A1 mutation in a Chinese kindred
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No Abstract. (Source: Prenatal Diagnosis)
Source: Prenatal Diagnosis - March 19, 2010 Category: Perinatology & Neonatology Authors: Pengfei Lin, Fei Mao, Qiji Liu, Changshun Shao, Chuanzhu Yan, Yaoqin Gong Source Type: journals
The impact of rapid aneuploidy detection (RAD) in addition to karyotyping versus karyotyping on maternal quality of life
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To assess the impact of rapid aneuploidy detection (RAD) combined with fetal karyotyping versus karyotyping only on maternal anxiety and health-related quality of life.Women choosing to undergo amniocentesis were selected into group 1, i.e. receiving a karyotype result only (n = 132) or to group 2, i.e. receiving both the result of RAD and karyotyping (n = 181).There were no systematic differences in time of RAD combined with karyotyping versus karyotyping only in terms of anxiety (P = 0.91), generic physical health (P = 0.76, P = 0.46), generic mental health (P = 0.52, P = 0.72), personal perceived control (P = 0.91) and ...
Source: Prenatal Diagnosis - March 19, 2010 Category: Perinatology & Neonatology Authors: E. M. A Boormans, E. Birnie, D. Oepkes, C. M. Bilardo, H. I. J. Wildschut, J. Creemers, G. J. Bonsel, J. M. M. van Lith, on behalf of the M.A.K.E.study group Source Type: journals
The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells
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This article reviews chondrogenesis and osteogenesis during skeletogenesis, and then considers the role of mechanics in regulating limb development and regenerative events such as fracture repair. However, observing skeletal changes under altered loading conditions can only partially explain the role of mechanics in controlling MSC differentiation. Increasingly, understanding how epigenetic factors, such as the mechanical environment, regulate stem cell fate is undertaken using tightly controlled in vitro models. Factors such as bioengineered surfaces, substrates, and bioreactor systems are used to control the mechanical f...
Source: Birth Defects Research Part C: Embryo Today: Reviews - March 18, 2010 Category: Perinatology & Neonatology Authors: Daniel J. Kelly, Christopher R. Jacobs Tags: Reviews Source Type: journals
Therapeutic potential of the immunomodulatory activities of adult mesenchymal stem cells
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Adult mesenchymal stem cells (MSCs) include a select population of resident cells within adult tissues, which retain the ability to differentiate along several tissue-specific lineages under defined media conditions and have finite expansion potential in vitro. These adult progenitor populations have been identified in various tissues, but it remains unclear exactly what role both transplanted and native MSCs play in processes of disease and regeneration. Interestingly, increasing evidence reveals a unique antiinflammatory immunomodulatory phenotype shared among this population, lending support to the idea that MSCs play a...
Source: Birth Defects Research Part C: Embryo Today: Reviews - March 18, 2010 Category: Perinatology & Neonatology Authors: Caren E. Petrie Aronin, Rocky S. Tuan Tags: Reviews Source Type: journals
Tissue-dependent induction of apoptosis by matrix metalloproteinase stromelysin-3 during amphibian metamorphosis
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Matrix metalloproteinases (MMPs) are a superfamily of Zn2+-dependent proteases that are capable of cleaving the proteinaceous component of the extracellular matrix (ECM). The ECM is a critical medium for cell-cell interactions and can also directly signal cells through cell surface ECM receptors, such as integrins. In addition, many growth factors and signaling molecules are stored in the ECM. Thus, ECM remodeling and/or degradation by MMPs are expected to affect cell fate and behavior during many developmental and pathological processes. Numerous studies have shown that the expression of MMP mRNAs and proteins associates ...
Source: Birth Defects Research Part C: Embryo Today: Reviews - March 18, 2010 Category: Perinatology & Neonatology Authors: Smita Mathew, Liezhen Fu, Takashi Hasebe, Atsuko Ishizuya-Oka, Yun-Bo Shi Tags: Reviews Source Type: journals
Extracellular matrix provides an optimal niche for the maintenance and propagation of mesenchymal stem cells
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Relatively little is known about the cellular and molecular mechanisms underlying the control of mesenchymal stem cell (MSC) proliferation, differentiation, and survival. This presents difficulties in following and characterizing cells along the lineage because of our inability to isolate and obtain a sufficient number of homogeneous MSCs using current culture systems for in vitro expansion. Adjusting the cellular machinery to allow greater proliferation can lead to other unwanted outcomes, such as unmanageable precancerous changes, or differentiation down an undesired pathway. Recently, it has become increasingly evident ...
Source: Birth Defects Research Part C: Embryo Today: Reviews - March 18, 2010 Category: Perinatology & Neonatology Authors: Xiao-Dong Chen Tags: Reviews Source Type: journals
Heparan sulfate in lung morphogenesis: The elephant in the room
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Heparan sulfate (HS) is a structurally complex polysaccharide located on the cell surface and in the extracellular matrix, where it participates in numerous biological processes through interactions with a vast number of regulatory proteins such as growth factors and morphogens. HS is crucial for lung development; disruption of HS synthesis in flies and mice results in a major aberration of airway branching, and in mice, it results in neonatal death as a consequence of malformed lungs and respiratory distress. Epithelial-mesenchymal interactions governing lung morphogenesis are directed by various diffusible proteins, many...
Source: Birth Defects Research Part C: Embryo Today: Reviews - March 18, 2010 Category: Perinatology & Neonatology Authors: Sophie M. Thompson, Edwin C. Jesudason, Jeremy E. Turnbull, David G. Fernig Tags: Reviews Source Type: journals
Basement membranes in development and disease
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Basement membranes (BMs) are specializations of the extracellular matrix that act as key mediators of development and disease. Their sheet like protein matrices typically serve to separate epithelial or endothelial cell layers from underlying mesenchymal tissues, providing both a biophysical support to overlying tissue as well as a hub to promote and regulate cell-cell and cell-protein interactions. In the latter context, the BM is increasingly being recognized as a mediator of growth factor interactions during development. In this review, we discuss recent findings regarding the structure of the BM and its roles in mediat...
Source: Birth Defects Research Part C: Embryo Today: Reviews - March 18, 2010 Category: Perinatology & Neonatology Authors: Fenny Wiradjaja, Tia DiTommaso, Ian Smyth Tags: Reviews Source Type: journals
First trimester maternal serum placental growth factor in trisomy 21 pregnancies
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To examine placental growth factor (PlGF) levels in first trimester maternal serum in trisomy 21 pregnancies and to investigate the potential value of PlGF in a first trimester screening test.First trimester maternal serum from 70 trisomy 21 cases and 375 euploid controls were retrospectively analyzed for PlGF using a DELFIA® Xpress immunoassay platform. Results were expressed as multiples of medians (MoM) for comparison.PlGF levels were significantly decreased in pregnancies with trisomy 21, 0.76 MoM versus 0.98 MoM in controls. Inclusion of PlGF into the first trimester combined test [maternal age, pregnancy associated ...
Source: Prenatal Diagnosis - March 18, 2010 Category: Perinatology & Neonatology Authors: N. J. Cowans, A. Stamatopoulou, K. Spencer Source Type: journals
Successful photocoagulation on both sides of inter-twin membrane for twin-twin transfusion syndrome in a case of iatrogenic septostomy after an amnioreduction
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No Abstract. (Source: Prenatal Diagnosis)
Source: Prenatal Diagnosis - March 18, 2010 Category: Perinatology & Neonatology Authors: Efua B. Leke, Ramesha Papanna, Kenneth J. Moise Jr, Anthony Johnson Source Type: journals
Mandibular dimensions and growth in 11- to 26-week-old Danish fetuses studied by 3D ultrasound
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To present normative data on prenatal mandibular morphology and growth.Fifty-four normal fetuses (Danish Caucasian) were included in the study (gestational age: 11-26 weeks). Fetuses were scanned using a GE Voluson 730 Expert 3D scanner. Scans were visualized and analyzed using GE 4DVIEWTM software. Mandibular dimensions [base length (B), ramus height (H), and total length (L)] and the mandibular angle ([phiv]) were measured, and the mandibular index was calculated. Method error was estimated by duplicate measurements. Growth was calculated by regressing measured variables on age.Mandibular measurements were found to be re...
Source: Prenatal Diagnosis - March 18, 2010 Category: Perinatology & Neonatology Authors: Nuno V. Hermann, Tron A. Darvann, Karin Sundberg, Sven Kreiborg, Connie Jørgensen Source Type: journals
Distributions of current and new first-trimester Down syndrome screening markers in twin pregnancies
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To study the distributions of pregnancy-associated plasma protein A (PAPP-A), the free [beta] subunit of human chorion gonadotrophin (f[beta]-hCG), A Disintegrin and Metalloprotease 12 (ADAM12) and Placental Protein 13 (PP13) in first trimester twin pregnancies.Serum marker concentrations were measured in monochorionic and dichorionic twin pregnancies and singleton controls to study differences in multiples of the gestation-specific normal medians (MoMs).Median PAPP-A and f[beta]-hCG MoMs were 2.03 and 1.87 for monochorionic twins (n = 116) and 2.18 and 1.89 for dichorionic twins (n = 650). Furthermore, ADAM12 and PP13 MoM...
Source: Prenatal Diagnosis - March 18, 2010 Category: Perinatology & Neonatology Authors: M. P. H. Koster, E. J. Wortelboer, Ph. Stoutenbeek, G. H. A. Visser, P. C. J. I. Schielen Source Type: journals
Adrenal function in newborns undergoing surgery
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mp; K L Watterberg (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 18, 2010 Category: Perinatology & Neonatology Authors: E F FernandezR MontmanK L Watterberg Tags: adrenal insufficiency surgery infants cortisol critically ill hypotension Source Type: journals
High-flow nasal cannula and extubation success in the premature infant: a comparison of two modalities
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& S A Dowd (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 18, 2010 Category: Perinatology & Neonatology Authors: S M MillerS A Dowd Tags: Vapotherm Fisher & Paykel premature infant extubation high flow nasal cannula Source Type: journals
The changing pattern of inhaled nitric oxide use in the neonatal intensive care unit
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& A R Spitzer (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 18, 2010 Category: Perinatology & Neonatology Authors: R H ClarkR L UrsprungM W WalkerD L EllsburyA R Spitzer Tags: neonate inhaled nitric oxide respiratory distress prematurity Source Type: journals
Effect of topical anesthesia and age on pain scores during retinopathy of prematurity screening
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mp; D K VanderVeen (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 18, 2010 Category: Perinatology & Neonatology Authors: M MehtaT MansfieldD K VanderVeen Tags: retinopathy of prematurity screening topical anesthesia Premature Infant Pain Profile PIPP Source Type: journals
Generating expected growth curves and Z-scores for premature infants
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amp; S C DonLevy (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 18, 2010 Category: Perinatology & Neonatology Authors: W R RiddleS C DonLevy Tags: growth charts neonates preterm infants Z-scores Source Type: journals
Maternal interleukin-6 (−174) C/C polymorphism is associated with chorioamnionitis and cystic periventricular leucomalacia of the preterm infant
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Maternal interleukin-6 (−174) C/C polymorphism is associated with chorioamnionitis and cystic periventricular leucomalacia of the preterm infant
Journal of Perinatology advance online publication, March 18, 2010. doi:10.1038/jp.2010.30
Authors: B Resch, A Radinger, C Mannhalter, B Horvath, A Binder, W Zenz, W Walcher, J Haas, W D Müller
& B Pertl (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 18, 2010 Category: Perinatology & Neonatology Authors: B ReschA RadingerC MannhalterB HorvathA BinderW ZenzW WalcherJ HaasW D MüllerB Pertl Tags: interleukin-6 G( −174)C polymorphism clinical chorioamnionitis cystic periventricular leukomalacia preterm newborn Source Type: journals
Anesthetic technique and postoperative outcome in preterm infants undergoing PDA closure
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& J Lavoie (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 18, 2010 Category: Perinatology & Neonatology Authors: A JanvierJ L MartinezK BarringtonJ Lavoie Tags: anaesthesia postoperative instability preterm infant ligation of ductus arteriosus Source Type: journals
The Treatment of Preeclampsia in a Rat Model Employing Digibind®
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This study investigated the effects of Digibind in a rat model of PE. We induced a syndrome in rats, which includes many of the phenotypic characteristics of human PE. Digibind, in escalating doses, was given on days 10 to 20 of pregnancy. Digibind produced significant lowering of the blood pressure and reduced proteinuria in our rat model of PE. However, it also did not avert IUGR. In view of these findings, in our experimental model of human PE, further studies in the quest for effective treatment of PE need to focus on pharmaceuticals that can remedy the syndrome without compromising the fetus.[...]© Thieme Medical P...
Source: American Journal of Perinatology - March 17, 2010 Category: Perinatology & Neonatology Source Type: journals
Mixoploidy: Perinatal Diagnosis and Pregnancy Outcome
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We report on two cases of abnormal midtrimester ultrasound showing placental abnormalities. Karyotype assessment showed mixoploidy, and both cases had satisfactory pregnancy outcome.[...]© Thieme Medical PublishersGet connected:Table of contents | Abstract | Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - March 17, 2010 Category: Perinatology & Neonatology Source Type: journals
Maternal Outcomes Associated with Planned Vaginal Versus Planned Primary Cesarean Delivery
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Amer J PerinatolDOI: 10.1055/s-0030-1249765ABSTRACTWe compared maternal morbidity between planned vaginal and planned cesarean delivery. A university hospital's database was queried for delivery outcomes. Between 1995 and 2005, 26,356 deliveries occurred. Subjects were divided into two groups: planned vaginal and planned cesarean delivery. This was based on intent to deliver vaginally or by cesarean, despite actual route of delivery. Planned vaginal delivery included successful vaginal delivery and labored cesarean delivery intended for vaginal delivery. Planned cesarean delivery included unlabored and labored cesarean del...
Source: American Journal of Perinatology - March 17, 2010 Category: Perinatology & Neonatology Source Type: journals
Risk of Cesarean Delivery When Second-Trimester Ultrasound Dating Disagrees with Definite Last Menstrual Period
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Amer J PerinatolDOI: 10.1055/s-0030-1249359ABSTRACTEstimates of gestational age based on early second-trimester ultrasound often differ from that based on the last menstrual period (LMP) even when a woman is certain about her LMP. Discrepancies in these gestational age estimates may be associated with an increased risk of cesarean section and low birth weight. We analyzed 7228 singleton, low-risk, white women from The Routine Antenatal Diagnostic Imaging with Ultrasound trial. The women were recruited at less than 14 weeks of gestation and received ultrasound exams between 15 and 22 weeks. Our results indicate that among n...
Source: American Journal of Perinatology - March 16, 2010 Category: Perinatology & Neonatology Source Type: journals
Digoxin Immune Fab Treatment for Severe Preeclampsia
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Amer J PerinatolDOI: 10.1055/s-0030-1249762ABSTRACTWe evaluated the efficacy, safety, and biological mechanisms of digoxin immune Fab (DIF) treatment of severe preeclampsia. Fifty-one severe preeclamptic patients were randomized in double-blind fashion to DIF ( = 24) or placebo ( = 27) for 48 hours. Primary outcomes were change in creatinine clearance (CrCl) at 24 to 48 hours and antihypertensive drug use. Serum sodium pump inhibition, a sequela of endogenous digitalis-like factors (EDLF), was also assessed. CrCl in DIF subjects was essentially unchanged from baseline versus a decrease with placebo ...
Source: American Journal of Perinatology - March 16, 2010 Category: Perinatology & Neonatology Source Type: journals
Oral versus Nasal Route for Placing Feeding Tubes: No Effect on Hypoxemia and Bradycardia in Infants with Apnea of Prematurity.
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Conclusion: We could not confirm an advantage of placing a feeding tube orally in these infants with AOP, as the oral route did not improve their symptoms of AOP. Possible explanations include: (i) the increase in nasal airway resistance by the 5-Fr nasogastric tube, inserted into the smaller nostril, is too small to have any effect on AOP; (ii) any benefit of the oral route is neutralized by the negative effects of an enhanced vagal stimulation, or (iii) study duration was too short to detect a difference in AOP.
PMID: 20234138 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - March 16, 2010 Category: Perinatology & Neonatology Authors: Bohnhorst B, Cech K, Peter C, Doerdelmann M Tags: Neonatology Source Type: journals
Lamellar Body Count and Stable Microbubble Test on Gastric Aspirates from Preterm Infants for the Diagnosis of Respiratory Distress Syndrome.
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Conclusion: LBC on gastric aspirates diluted in a solution of dithiothreitol can be rapidly and easily performed, and may be used alone or in combination with SMT as a predictor of RDS, allowing selective prophylaxis or very early treatment only in surfactant-deficient newborns.
PMID: 20234139 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - March 16, 2010 Category: Perinatology & Neonatology Authors: Daniel IW, Fiori HH, Piva JP, Munhoz TP, Nectoux AV, Fiori RM Tags: Neonatology Source Type: journals
Effect of Bifidobacterium lactis on the Incidence of Nosocomial Infections in Very-Low-Birth-Weight Infants: A Randomized Controlled Trial.
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Conclusion: In the present setting, B. lactis at a dosage of 6 x 2.0 x 10(9) CFU/kg/day (12 billion CFU/kg/day) did not reduce the incidence density of nosocomial infections in VLBW infants. No adverse effect of B. lactis was observed.
PMID: 20234140 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - March 16, 2010 Category: Perinatology & Neonatology Authors: Mihatsch WA, Vossbeck S, Eikmanns B, Hoegel J, Pohlandt F Tags: Neonatology Source Type: journals
Effects of Maternal Cervical Incompetence on Morbidity and Mortality of Very Low Birthweight Neonates.
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Conclusion: We found that cervical incompetence does not negatively affect the postnatal adverse outcomes and mortality after stratified analysis by gestational age.
PMID: 20234141 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - March 16, 2010 Category: Perinatology & Neonatology Authors: Sung TJ, Lee KY, Ju YS Tags: Neonatology Source Type: journals
Standardized versus Individualized Parenteral Nutrition in Very Low Birth Weight Infants: A Comparative Study.
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Conclusions: Compared to STD-PN infants, IND-PN infants achieved significantly better growth without added clinical or laboratory complications, had a shorter period of exclusive PN and less electrolyte corrections. IND-PN, in accordance with the current more aggressive nutritional approach, appears optimal for PN of VLBW infants. Yet, STD-PN with adequate composition is an appropriate alternative.
PMID: 20234142 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - March 16, 2010 Category: Perinatology & Neonatology Authors: Smolkin T, Diab G, Shohat I, Jubran H, Blazer S, Rozen GS, Makhoul IR Tags: Neonatology Source Type: journals
Assessment of a New Piezoelectric Transducer Sensor for Noninvasive Cardiorespiratory Monitoring of Newborn Infants in the NICU.
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Conclusion: The PZT sensor is noninvasive and does not cause skin irritation, and we believe it does provide a reliable, accurate cardiorespiratory monitoring tool for use in the NICU, although the issue of mechanical-ventilation noise remains to be solved.
PMID: 20234143 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - March 16, 2010 Category: Perinatology & Neonatology Authors: Sato S, Ishida-Nakajima W, Ishida A, Kawamura M, Miura S, Ono K, Inagaki N, Takada G, Takahashi T Tags: Neonatology Source Type: journals
Effect of Furosemide on Ductal Closure and Renal Function in Indomethacin-Treated Preterm Infants during the Early Neonatal Period.
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Conclusions: Use of furosemide in combination with indomethacin increased the incidence of ARF but did not affect the PDA closure rate in preterm infants.
PMID: 20234144 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - March 16, 2010 Category: Perinatology & Neonatology Authors: Lee BS, Byun SY, Chung ML, Chang JY, Kim HY, Kim EA, Kim KS, Pi SY Tags: Neonatology Source Type: journals
Maturation of Adrenal Function Determined by Urinary Glucocorticoid Steroid Excretion Rates in Preterm Infants of More than 30 Weeks of Gestational Age.
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Conclusion: There was a positive association between severity of illness and CPR in preterm infants >30 weeks, indicating a maturation of the adrenal stress response.
PMID: 20234145 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - March 16, 2010 Category: Perinatology & Neonatology Authors: Grofer B, Bödeker RH, Gortner L, Heckmann M Tags: Neonatology Source Type: journals
What Is Their Fate after Magnesium Sulfate?
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PMID: 20234146 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - March 16, 2010 Category: Perinatology & Neonatology Authors: Leonard AS, Mikati MA Tags: Neonatology Source Type: journals
Aortic isthmus Doppler velocimetry: role in assessment of preterm fetal growth restriction
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Intrauterine fetal growth restriction (IUGR) is an important pregnancy complication associated with significant adverse clinical outcome, stillbirth, perinatal morbidity and cerebral palsy. To date, no uniformly accepted management protocol of Doppler surveillance that reduces mortality and cognitive morbidity has emerged. Aortic isthmus (AoI) evaluation has been proposed as a potential monitoring tool for IUGR fetuses. In this review, the current knowledge of the relationship between AoI Doppler velocimetry and preterm fetal growth restriction is reviewed. Relevant technical aspects and reproducibility data are reviewed a...
Source: Prenatal Diagnosis - March 16, 2010 Category: Perinatology & Neonatology Authors: M. M. Kennelly, N. Farah, M. J. Turner, B. Stuart Source Type: journals
Congenital urinary bladder outlet obstruction
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Research ArticlesMARIE-KLAIRE FARRUGIA, ADRIAN S WOOLF, Fetal and Maternal Medicine Review, Volume 21 Issue 01 , pp 55-73Abstract (Source: Fetal and Maternal Medicine Review)
Source: Fetal and Maternal Medicine Review - March 15, 2010 Category: Perinatology & Neonatology Source Type: journals
Cystic fibrosis – a guide for clinicians in reproductive and obstetric medicine
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Research ArticlesFRANK P EDENBOROUGH, ALISON M MORTON, Fetal and Maternal Medicine Review, Volume 21 Issue 01 , pp 36-54Abstract (Source: Fetal and Maternal Medicine Review)
Source: Fetal and Maternal Medicine Review - March 15, 2010 Category: Perinatology & Neonatology Source Type: journals
Fetal anaesthesia: is this necessary for fetoscopic therapy?
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Research ArticlesMARC VAN DE VELDE, FREDERIK DE BUCK, TIM VAN MIEGHEM, LEONARDO GUCCIARDO, PHILIP DE KONINCK, JAN DEPREST, Fetal and Maternal Medicine Review, Volume 21 Issue 01 , pp 24-35Abstract (Source: Fetal and Maternal Medicine Review)
Source: Fetal and Maternal Medicine Review - March 15, 2010 Category: Perinatology & Neonatology Source Type: journals
Proteinuria in preeclampsia: from bench to bedside
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Research ArticlesANGUS RITCHIE, MARK A BROWN, Fetal and Maternal Medicine Review, Volume 21 Issue 01 , pp 1-23Abstract (Source: Fetal and Maternal Medicine Review)
Source: Fetal and Maternal Medicine Review - March 15, 2010 Category: Perinatology & Neonatology Source Type: journals
Treatment of asphyxiated newborns with moderate hypothermia in routine clinical practice: how cooling is managed in the UK outside a clinical trial
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(Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - March 15, 2010 Category: Perinatology & Neonatology Authors: Quinn, M. W, Munyard, P. F Tags: PostScript Source Type: journals
Survival of extremely preterm infants
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(Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - March 15, 2010 Category: Perinatology & Neonatology Authors: Matta, N., Young, D., Boulton, R., Mactier, H. Tags: PostScript Source Type: journals
Systemic inflammatory response syndrome (SIRS) definition and correlation with early-onset bacterial infection of the newborn
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(Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - March 15, 2010 Category: Perinatology & Neonatology Authors: Hofer, N, Miiller, W, Resch, B Tags: PostScript Source Type: journals
The Italian Ministry of Health recommends resuscitation for all preterm infants irrespective of gestational age and parental consent
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(Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - March 15, 2010 Category: Perinatology & Neonatology Authors: Pignotti, M S., Moratti, S. Tags: PostScript Source Type: journals
Choice of booking: postnatal implications for infants requiring neonatal community care
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(Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - March 15, 2010 Category: Perinatology & Neonatology Authors: Mahaveer, A K, May, J, Curley, A Tags: PostScript Source Type: journals
How minimal is "minimal" enteral feeding?
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(Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - March 15, 2010 Category: Perinatology & Neonatology Authors: McHale, S M, McCarthy, R, O'Donnell, C P F Tags: PostScript Source Type: journals
Neonatal albumin infusions in paediatric intensive care
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(Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - March 15, 2010 Category: Perinatology & Neonatology Authors: Low, E, Healy, M, Molloy, E J Tags: Postscript Source Type: journals
Pain in neonates during screening for retinopathy of prematurity using binocular indirect ophthalmoscopy and wide-fi eld digital retinal imaging: a randomised comparison
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Conclusion
WFDRI and BIO with eyelid speculum are similarly painful for infants. The authors speculate that the eyelid speculum rather than the examination method may contribute most to the pain experienced. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - March 15, 2010 Category: Perinatology & Neonatology Authors: Dhaliwal, C A, Wright, E, McIntosh, N, Dhaliwal, K, Fleck, B W Tags: Eye Diseases, Pain (neurology), Ophthalmology, Child health, Infant health, Neonatal health, Screening (epidemiology), Screening (public health) Short reports Source Type: journals
