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Perinatology & Neonatology

This page shows you the most recent publications within this specialty of the MedWorm directory.

Local inactivation of Gpr88 in the nucleus accumbens attenuates behavioral deficits elicited by the neonatal administration of phencyclidine in rats
allet & R Meloni (Source: Molecular Psychiatry)
Source: Molecular Psychiatry - August 26, 2014 Category: Psychiatry Authors: M IngallinesiL Le BouilN Faucon BiguetA Do ThiC Mannoury la CourM J MillanP RavassardJ MalletR Meloni Source Type: research

Marked methylation changes in intestinal genes during the perinatal period of preterm neonates
Conclusions: Pre- and postnatal changes in intestinal DNA methylation may contribute to high NEC sensitivity in preterm neonates. Optimizing gene methylation changes via environmental stimuli (e.g. diet, nutrition, gut microbiota), may help to make immature newborn infants more resistant to gut dysfunctions, both short and long term. (Source: BMC Genomics - Latest articles)
Source: BMC Genomics - Latest articles - August 26, 2014 Category: Genetics & Stem Cells Authors: Fei GaoJuyong ZhangPingping JiangDesheng GongJun-Wen WangYudong XiaMette ØstergaardJun WangPer Sangild Source Type: research

Human neonatal microbiome [Microbiology]
In the weeks after birth, the gut acquires a nascent microbiome, and starts its transition to bacterial population equilibrium. This early-in-life microbial population quite likely influences later-in-life host biology. However, we know little about the governance of community development: does the gut serve as a passive incubator where the first... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - August 26, 2014 Category: Science Authors: La Rosa, P. S., Warner, B. B., Zhou, Y., Weinstock, G. M., Sodergren, E., Hall-Moore, C. M., Stevens, H. J., Bennett, W. E., Shaikh, N., Linneman, L. A., Hoffmann, J. A., Hamvas, A., Deych, E., Shands, B. A., Shannon, W. D., Tarr, P. I. Tags: Biological Sciences Source Type: research

Validation of Registries: A Neglected, but Indispensable Investment
(Source: Paediatric and Perinatal Epidemiology)
Source: Paediatric and Perinatal Epidemiology - August 26, 2014 Category: Perinatology & Neonatology Authors: Lone Krebs, Jens Langhoff‐Roos Tags: Commentary Source Type: research

Using Bayesian Models to Assess the Effects of Under‐reporting of Cannabis Use on the Association with Birth Defects, National Birth Defects Prevention Study, 1997–2005
ConclusionsUnder‐reporting of the exposure may have obscured some cannabis‐birth defect associations in previous studies. However, the resulting bias is likely to be limited. (Source: Paediatric and Perinatal Epidemiology)
Source: Paediatric and Perinatal Epidemiology - August 26, 2014 Category: Perinatology & Neonatology Authors: Marleen M. H. J. Gelder, A. Rogier T. Donders, Owen Devine, Nel Roeleveld, Jennita Reefhuis, Tags: Methodology Article Source Type: research

Issue Information
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - August 26, 2014 Category: Perinatology & Neonatology Tags: Issue Information Source Type: research

Papers from the eighth international neural tube defects conference
(Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - August 26, 2014 Category: Perinatology & Neonatology Tags: Editorial Source Type: research

Index
Note: Page numbers of article titles are in boldface type. Abdominal ectopic kidney, 683–684 (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 25, 2014 Category: Perinatology & Neonatology Source Type: research

CME Accreditation Page
(Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 25, 2014 Category: Perinatology & Neonatology Source Type: research

Forthcoming Issues
Controversies in Perinatology Robert M. Kliegman and Robert H. Lane, Editors (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 25, 2014 Category: Perinatology & Neonatology Source Type: research

Contents
Lucky Jain Michelle N. Rheault and Larry A. Greenbaum (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 25, 2014 Category: Perinatology & Neonatology Source Type: research

Contributors
LUCKY JAIN, MD, MBA Richard W. Blumberg Professor and Executive Vice Chairman, Department of Pediatrics, Emory University School of Medicine; Executive Medical Director, Children’s Physician Group, Emory Children’s Center, Children’s Healthcare of Atlanta, Atlanta, Georgia (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - August 25, 2014 Category: Perinatology & Neonatology Source Type: research

Successful transportation managing common respiratory conditions of precious cargo: becoming an expert neonatal transport nurse.
PMID: 25136748 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Authors: Snow TM Tags: Adv Neonatal Care Source Type: research

Responding to traumatic birth: subgaleal hemorrhage, assessment, and management during transport.
Abstract Subgaleal hemorrhage is an uncommon but often fatal complication of a traumatic birth. Careful assessment and monitoring of the infant following birth are necessary to ensure prompt intervention, referral, and improved outcomes. Additional care, planning, and communication are especially important in the transport environment. PMID: 25136749 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Authors: Schierholz E, Walker SR Tags: Adv Neonatal Care Source Type: research

Family-centered care during acute neonatal transport.
CONCLUSIONS: The integration of FCC core concepts during an acute neonatal transport is important to parents. The orientation of parents to FCC during the transport process may facilitate communication and help them become active participants in their infants' care. PMID: 25136750 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Authors: Mullaney DM, Edwards WH, DeGrazia M Tags: Adv Neonatal Care Source Type: research

Neonatal transport supplement.
Authors: PMID: 25136753 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Tags: Adv Neonatal Care Source Type: research

Managing common neonatal respiratory conditions during transport.
This article reviews the history of respiratory management during neonatal transport and discusses current methodologies and innovations in transport respiratory management. PMID: 25136752 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Authors: Coe KL, Jamie SF, Baskerville RM Tags: Adv Neonatal Care Source Type: research

Writing an abstract to sell your scholarly work.
Authors: PMID: 25137596 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Tags: Adv Neonatal Care Source Type: research

NANN Shares Member Spotlight and New Educational Offerings.
Authors: PMID: 25137598 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Tags: Adv Neonatal Care Source Type: research

Noteworthy professional news.
Authors: PMID: 25137597 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Tags: Adv Neonatal Care Source Type: research

Wolf-hirschhorn syndrome: a case study and disease overview.
Abstract Wolf-Hirschhorn syndrome is caused by a deletion of a segment on the short arm (p) of chromosome 4. The major features of this disorder include a characteristic facial appearance known as the "Greek helmet," delayed growth and development; prenatally and postnatally, intellectual disabilities, and seizures. To provide comprehensive and appropriate nursing and medical care to infants with Wolf-Hirschhorn syndrome, it is imperative to know and understand the disorder. A case study of a 36 weeks' gestational age white-Hispanic male infant with Wolf-Hirschhorn syndrome is presented with the purpose of increasi...
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Authors: Bailey R Tags: Adv Neonatal Care Source Type: research

Osteogenesis Imperfecta Types I-XI: Implications for the Neonatal Nurse.
Authors: PMID: 25137599 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Tags: Adv Neonatal Care Source Type: research

The Neonatal Nurse's Role in Preventing Abusive Head Trauma.
Abstract Abusive head trauma in infants occurs in 24.6 to 39.8 per 100,000 infants in developed countries. Abusive head trauma refers to any type of intentional head trauma an infant sustains, as a result of an injury to the skull or intracranial contents from a blunt force and/or violent shaking. The clinical question was: what evidence-based interventions have been implemented by neonatal nurses to prevent abusive head trauma in infants? PubMed was searched to obtain English language publications from 2005 to May 2014 for interventions focused on preventing abusive head trauma using the key term "shaken baby synd...
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Authors: Allen KA Tags: Adv Neonatal Care Source Type: research

What Opportunities Does NANN Provide to Support Evidence-Based Practice and Research?
PMID: 25137602 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Authors: Samra HA, Damato E, Rubarth LB Tags: Adv Neonatal Care Source Type: research

Vitamin A administration using nasogastric tubes
Administering oral medications to very small and immature neonates using nasogastric tube (NGT) is often necessary because of their inability to swallow. Inappropriate prescribing behavior and incorrect procedure in the extemporaneous preparation of oral suspensions given via NGT may be harmful for infants and children alike. Of note, many drugs have not been tested for oral absorption and with regard to bioavailability following NGT dosing [1]. Moreover, physicochemical incompatibilities with tube materials may also be present and of relevance [2]. (Source: Early Human Development)
Source: Early Human Development - August 25, 2014 Category: Perinatology & Neonatology Authors: Sascha Meyer, Ludwig Gortner, Dominik Monz, Ellen Maurer, Donatus Nohr, Hans Konrad Biesalski, on behalf of the NeoVitaA Study Group Source Type: research

Neonatal monosodium glutamate treatment causes obesity, diabetes, and macrovesicular steatohepatitis with liver nodules in DIAR mice
ConclusionsDIAR‐MSG had NASH‐like liver pathology and liver nodules typically associated with MS symptoms. DIAR‐MSG provides a valuable animal model to analyze NASH pathogenesis and carcinogenesis. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - August 25, 2014 Category: Gastroenterology Authors: Koichi Tsuneyama, Takeshi Nishida, Hayato Baba, Shu Taira, Makoto Fujimoto, Kazuhiro Nomoto, Shinichi Hayashi, Shigeharu Miwa, Takahiko Nakajima, Mitsuko Sutoh, Emu Oda, Ryoji Hokao, Johji Imura Tags: Hepatology Source Type: research

Fetoscopic laser coagulation for twin–twin transfusion syndrome before 17 weeks' gestation: laser data, complications and neonatal outcome
ConclusionIn the event of early TTTS, fetoscopic laser coagulation is technically feasible before 17 gestational weeks and obstetric and neonatal outcomes are comparable with those in cases of laser treatment performed after 17 weeks. Copyright © 2014 ISUOG. Published by John Wiley & Sons Ltd (Source: Ultrasound in Obstetrics and Gynecology)
Source: Ultrasound in Obstetrics and Gynecology - August 25, 2014 Category: Radiology Authors: L. Lecointre, N. Sananes, A. S. Weingertner, M. Kohler, F. Guerra, G. Fritz, B. Viville, B. Langer, I. Nisand, R. Favre Tags: Original Paper Source Type: research

Fetal MRI insular cortical morphometry and its association with neurobehavior in late‐onset small‐for‐gestational‐age fetuses
ConclusionsInsular cortical morphometry was significantly different in late‐onset SGA fetuses and correlated with poorer neurobehavioral performance. These data support the impact of growth restriction on brain development and the potential value of cortical assessment as a biomarker of neurodevelopment in at‐risk fetuses. Copyright © 2014 ISUOG. Published by John Wiley & Sons Ltd (Source: Ultrasound in Obstetrics and Gynecology)
Source: Ultrasound in Obstetrics and Gynecology - August 25, 2014 Category: Radiology Authors: G. Egaña‐Ugrinovic, M. Sanz‐Cortes, F. Figueras, C. Couve‐Perez, E. Gratacós Tags: Original Paper Source Type: research

Rates of Intracardiac Umbilical Venous Catheter Placement in Neonates
Conclusions— A high proportion of ELBW neonates in a busy NICU had UVCs placed with the tips in the RA or LA despite common placement practices. We recommend adding TNE to radiography to position UVCs, especially in ELBW neonates. (Source: Journal of Ultrasound in Medicine)
Source: Journal of Ultrasound in Medicine - August 25, 2014 Category: Radiology Authors: Harabor, A., Soraisham, A. Tags: Original Research Source Type: research

Clinical Utility of Ductus Venosus Flow in Fetuses With Right-Sided Congenital Heart Disease
Conclusions— Fetuses with obstructive right-sided congenital heart disease have ductus venosus reversal at baseline; an abnormal peak velocity index can be used to predict compromise. Fetuses with nonobstructive disease rarely have ductus venosus reversal; the peak velocity index cannot be used to predict outcomes in this group. (Source: Journal of Ultrasound in Medicine)
Source: Journal of Ultrasound in Medicine - August 25, 2014 Category: Radiology Authors: Arya, B., Krishnan, A., Donofrio, M. T. Tags: Original Research Source Type: research

Does Early Second-Trimester Sonography Predict Adverse Perinatal Outcomes in Monochorionic Diamniotic Twin Pregnancies?
Conclusions— In our cohort, only second-trimester abdominal circumference and estimated fetal weight discordances in monochorionic diamniotic twin pregnancies were predictive of adverse composite obstetric outcomes. Twin-twin transfusion syndrome and adverse neonatal outcomes were not predicted by any of the intertwin discordances measured. (Source: Journal of Ultrasound in Medicine)
Source: Journal of Ultrasound in Medicine - August 25, 2014 Category: Radiology Authors: Allaf, M. B., Campbell, W. A., Vintzileos, A. M., Haeri, S., Javadian, P., Shamshirsaz, A. A., Ogburn, P., Figueroa, R., Wax, J., Markenson, G., Chavez, M. R., Ravangard, S. F., Ruano, R., Sangi-Haghpeykar, H., Salmanian, B., Meyer, M., Johnson, J., Ozhan Tags: Original Research Source Type: research

Father participation in a community‐doula home‐visiting intervention with young, african american mothers
This article examines the extent and nature of father participation in a perinatal, community‐based doula home‐visiting intervention that served young, African American mothers from low‐income backgrounds and their infants. Home‐visitor service records were used to assess the quantity, setting, and content of father‐attended visits. Correlates of fathers’ participation and thematic insights from mothers’ and home‐visitors’ perspectives on how fathers perceived and interacted with the home‐visiting program were analyzed to further characterize the nature of father participation. Although the community‐...
Source: Infant Mental Health Journal - August 25, 2014 Category: Child Development Authors: Matthew J. Thullen, Stephen Edward McMillin, Jon Korfmacher, Marisha L. Humphries, Jennifer Bellamy, Linda Henson, Sydney Hans Tags: ARTICLE Source Type: research

Protective effects of melatonin therapy in model for neonatal hyperoxic lung injury.
Conclusion • MT therapy was found to have a protective effect in a model for hyperoxic lung injury in neonatal rats. Therefore, the research team suggests that MT therapy may be used for prevention of BPD in preterm infants after confirmation of this data by future clinical studies. PMID: 25141368 [PubMed - in process] (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - August 23, 2014 Category: Complementary Medicine Authors: Suleymanoglu S, Cekmez F, Cetinkaya M, Tayman C, Canpolat FE, Kafa IM, Tanju A, Arzıman IK, Fidancı M, Tunc T, Sarıcı SU Tags: Altern Ther Health Med Source Type: research

Neurodevelopmental assessment after anesthesia in childhood: review of the literature and recommendations.
Abstract Preclinical studies have established that anesthesia is toxic to the brain in neonatal animals, but scant research investigates the neurodevelopmental effects of exposure to anesthesia. In this article, we discuss the issue of outcome measurement of children after anesthesia administered between infancy and approximately 4 years of age. Recent studies are reviewed with the goal of understanding the contributions and limitations of the extant literature with respect to neurodevelopmental outcome. A review of school-based information (academic achievement and learning disability characterization), which are ...
Source: Anesthesia and Analgesia - August 23, 2014 Category: Anesthesiology Authors: Beers SR, Rofey DL, McIntyre KA Tags: Anesth Analg Source Type: research

The neonatal nurse's role in preventing abusive head trauma - Allen KA.
Abusive head trauma in infants occurs in 24.6 to 39.8 per 100,000 infants in developed countries. Abusive head trauma refers to any type of intentional head trauma an infant sustains, as a result of an injury to the skull or intracranial contents from a bl... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - August 23, 2014 Category: Global & Universal Tags: Age: Infants and Children Source Type: news

Impact of oxygen concentration on time to resolution of spontaneous pneumothorax in term infants: a population based cohort study
Conclusions: Supplemental oxygen use or nitrogen washout was not associated with faster resolution of SP. Infants treated with room air remained stable and did not require supplemental oxygen at any point of their admission. (Source: BMC Pediatrics - Latest articles)
Source: BMC Pediatrics - Latest articles - August 23, 2014 Category: Pediatrics Authors: Huma ShaireenYacov RabiAmy MetcalfeMajeeda KamaluddeenHarish AminAlbert AkiermanAbhay Lodha Source Type: research

Haematopoietic development and leukaemia in Down syndrome
Summary Children with constitutional trisomy 21 (cT21, Down Syndrome, DS) are at a higher risk for both myeloid and B‐lymphoid leukaemias. The myeloid leukaemias are often preceded by a transient neonatal pre‐leukaemic syndrome, Transient Abnormal Myelopoiesis (TAM). TAM is caused by cooperation between cT21 and acquired somatic N‐terminal truncating mutations in the key haematopoietic transcription factor GATA1. These mutations, which are not leukaemogenic in the absence of cT21, are found in almost one‐third of neonates with DS. Analysis of primary human fetal liver haematopoietic cells and of human embryonic ste...
Source: British Journal of Haematology - August 22, 2014 Category: Hematology Authors: Irene Roberts, Shai Izraeli Tags: Review Source Type: research

Folding and Function of a Proinsulin Diastereomer [Molecular Bases of Disease]
Misfolding of proinsulin variants in the pancreatic β-cell, a monogenic cause of permanent neonatal-onset diabetes mellitus, provides a model for a disease of protein toxicity. A hot spot for such clinical mutations is found at position B8, conserved as glycine within the vertebrate insulin superfamily. We set out to investigate the molecular basis of the aberrant properties of a proinsulin clinical mutant in which residue GlyB8 is replaced by SerB8. Modular total chemical synthesis was used to prepare the wild-type [GlyB8]proinsulin molecule and three analogs: [d-AlaB8]proinsulin, [l-AlaB8]proinsulin, and the clinical mu...
Source: Journal of Biological Chemistry - August 22, 2014 Category: Chemistry Authors: Avital-Shmilovici, M., Whittaker, J., Weiss, M. A., Kent, S. B. H. Tags: Protein Structure and Folding Source Type: research

Dying neurons in thalamus of asphyxiated term newborns and rats are autophagic
ABSTRACT Objective: Neonatal hypoxic‐ischemic encephalopathy (HIE) still carries a high burden by its mortality and long term neurological morbidity in survivors. Apart from hypothermia, there is no acknowledged therapy for HIE, reflecting the lack of mechanistic understanding of its pathophysiology. (Macro)autophagy, a physiological intracellular process of lysosomal degradation has been proposed to be excessively activated in excitotoxic conditions such as HIE. The present study examines whether neuronal autophagy in the thalamus of asphyxiated human newborns or P7 rats is enhanced and related to neuronal death process...
Source: Annals of Neurology - August 22, 2014 Category: Neurology Authors: Vanessa Ginet, Marie P. Pittet, Coralie Rummel, Maria Chiara Osterheld, Reto Meuli, Peter G.H Clarke, Julien Puyal, Anita C. Truttmann Tags: Research Article Source Type: research

Effectiveness of progestogens to improve perinatal outcome in twin pregnancies: an individual participant data meta‐analysis
BackgroundIn twin pregnancies, the rates of adverse perinatal outcome and subsequent long‐term morbidity are substantial, and mainly result from preterm birth (PTB). ObjectivesTo assess the effectiveness of progestogen treatment in the prevention of neonatal morbidity or PTB in twin pregnancies using individual participant data meta‐analysis (IPDMA). Search strategyWe searched international scientific databases, trial registration websites, and references of identified articles. Selection criteriaRandomised clinical trials (RCTs) of 17–hydroxyprogesterone caproate (17Pc) or vaginally administered natural progesterone...
Source: BJOG: An International Journal of Obstetrics and Gynaecology - August 22, 2014 Category: OBGYN Authors: E Schuit, S Stock, L Rode, DJ Rouse, AC Lim, JE Norman, AH Nassar, V Serra, CA Combs, C Vayssiere, MM Aboulghar, S Wood, E Çetingöz, CM Briery, EB Fonseca, K Worda, A Tabor, EA Thom, SN Caritis, J Awwad, IM Usta, A Perales, J Meseguer, K Maurel, T Garit Tags: Systematic Review Source Type: research

A single centre study on birth of children with transfusion dependent thalassaemia in Malaysia and reasons for ineffective prevention
ConclusionThe current poor uptake of voluntary thalassaemia screening in Malaysia and inadequate access to counselling and prenatal diagnostic services contributed to ineffective prevention. A considerable number of Malaysian Muslims may accept the termination option if given access to comprehensive genetic counselling services. This article is protected by copyright. All rights reserved. (Source: Prenatal Diagnosis)
Source: Prenatal Diagnosis - August 22, 2014 Category: Perinatology & Neonatology Authors: C. F. Ngim, H. Ibrahim, N. M. Lai, C. S. Ng Tags: Original Article Source Type: research

Psychological impact of first‐trimester prevention for preeclampsia on anxiety
ConclusionA strategy of first‐trimester screening for preeclampsia does not increase maternal anxiety. This article is protected by copyright. All rights reserved. (Source: Prenatal Diagnosis)
Source: Prenatal Diagnosis - August 22, 2014 Category: Perinatology & Neonatology Authors: Serena Simeone, Cristina Lojo, Lluïsa Garcia‐Esteve, Stefania Triunfo, Francesca Crovetto, Angela Arranz, Eduard Gratacos, Francesc Figueras Tags: Original Article Source Type: research

More than a gut feeling – sonographic prenatal diagnosis of imperforate anus in a high‐risk population
ConclusionsIn a CAKUT population, absence of the AM in the posterior perineal triangle in the axial trans‐perineal view emerges as an important sonographic marker for prenatal diagnosis of AA. © 2014 John Wiley & Sons, Ltd. (Source: Prenatal Diagnosis)
Source: Prenatal Diagnosis - August 22, 2014 Category: Perinatology & Neonatology Authors: Sharon Perlman, Ron Bilik, Leah Leibovitch, Eldad Katorza, Reuven Achiron, Yinon Gilboa Tags: Original Article Source Type: research

Design considerations for point-of-care clinical trials comparing methadone and buprenorphine treatment for opioid dependence in pregnancy and for neonatal abstinence syndrome
The growing opioid-use epidemic in the U.S. has been associated with a significant increase in the prevalence of pregnant opioid-dependent women and of neonatal abstinence syndrome (NAS), which is caused by withdrawal from in-utero exposure to drugs. While methadone-maintenance currently is the standard of care for opioid dependence during pregnancy, recent research suggests that buprenorphine-maintenance may be associated with shorter infant hospital lengths of stay (LOS) relative to methadone-maintenance. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - August 22, 2014 Category: Radiology Authors: Theresa Winhusen, Christine Wilder, Scott L. Wexelblatt, Jeffrey Theobald, Eric S. Hall, Daniel Lewis, James Van Hook, Michael Marcotte Source Type: research

Therapeutic hypothermia on transport: providing safe and effective cooling therapy as the link between birth hospital and the neonatal intensive care unit.
Abstract Therapeutic hypothermia as a neuroprotective strategy in neonates is an established standard of care for infants with hypoxic-ischemic encephalopathy (HIE) in tertiary care neonatal intensive care units (NICUs). To maximize the neuroprotective effect in infants with HIE, hypothermia is initiated as soon as possible after birth. Many infants who would benefit from therapeutic hypothermia are not born at centers that have intensive care units or offer therapeutic hypothermia and are thus transported to a tertiary care center with a NICU, offering specialty services of therapeutic hypothermia and pediatric ne...
Source: Adv Data - August 21, 2014 Category: Epidemiology Authors: Schierholz E Tags: Adv Neonatal Care Source Type: research

The selective noradrenergic reuptake inhibitor reboxetine restores spatial learning deficits, biochemical changes, and hippocampal synaptic plasticity in an animal model of depression
This study furthers the existing understanding of the effects of antidepressants on learning, memory, and synaptic plasticity and could ultimately assist in the development of better therapeutic strategies to treat depression and associated cognitive impairments. © 2014 Wiley Periodicals, Inc. (Source: Journal of Neuroscience Research)
Source: Journal of Neuroscience Research - August 21, 2014 Category: Neuroscience Authors: V. Bhagya, B.N. Srikumar, T.R. Raju, B.S. Shankaranarayana Rao Tags: Research Article Source Type: research

Establishing a reference range for triiodothyronine levels in preterm infants
Thyroid dysfunction affects clinical complications in preterm infants and older children. However, thyroid hormone replacement in preterm infants has no proven benefits, possibly owing to the lack of an appropriate reference range for thyroid hormone levels. We aimed to establish a reference range for triiodothyronine (T3) levels at 1-month postnatal age (PNA) in preterm infants. (Source: Early Human Development)
Source: Early Human Development - August 21, 2014 Category: Perinatology & Neonatology Authors: Ki Won Oh, Mi Sung Koo, Hye Won Park, Mi Lim Chung, Min-ho Kim, Gina Lim Source Type: research

Predicting the outcome of specific language impairment at five years of age through early developmental assessment in preterm infants
Very preterm infants ( (Source: Early Human Development)
Source: Early Human Development - August 21, 2014 Category: Perinatology & Neonatology Authors: Patricia L. Woods, Ingrid Rieger, Crista Wocadlo, Adrienne Gordon Source Type: research