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This page shows you the most recent publications within this specialty of the MedWorm directory.

1: Fetal ECG analysis of the ST segment as an adjunct to intrapartum fetal heart rate monitoring: a randomized clinical trial
Fetal ECG analysis of the ST segment (STAN) is used in Europe as an adjunct to conventional intrapartum fetal heart rate (FHR) monitoring. We sought to determine whether STAN improves perinatal outcomes and decreases operative deliveries at 26 hospitals within the United States. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: George Saade Tags: Oral plenary session I Source Type: research

5: Nifedipine versus atosiban for tocolysis in preterm labour (Assessment of Perinatal Outcome after Specific Tocolysis in Early Labour: APOSTEL III-trial)
To compare the effectiveness and safety of nifedipine and atosiban for tocolysis in women with preterm labour on perinatal outcome and prolongation of pregnancy. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Elvira Vliet, Ewoud Schuit, Karst Heida, Marjolein Kok, Wilfried Gyselaers, Martina Porath, Mallory Woiski, Caroline Bax, Kitty Bloemenkamp, Hubertina Scheepers, Yves Jacquemyn, Erik van Beek, Johannes Duvekot, Maureen Franssen, Joke Kok, Joris Van der Po Tags: Oral plenary session I Source Type: research

9: Neonatal, not maternal, copy number variants are associated with spontaneous preterm birth
Copy number variants (CNVs) contribute to human genetic diversity and are associated with complex disorders. Given the complex nature of spontaneous preterm birth (SPTB), we sought to examine the association between maternal or neonatal CNVs and SPTB at (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Joseph Biggio, Feifei Xiao, Don Baldwin, Radek Bukowski, Samuel Parry, M. Esplin, William Andrews, George Saade, Michael Varner, Yoel Sadovsky, Uma Reddy, John Ilekis, Heping Zhang Tags: Oral concurrent session 1 Source Type: research

12: Composite neonatal morbidity and cerebral palsy between presenting versus non-presenting twin
The primary objective was to ascertain if the composite neonatal morbidity (CNM) differs between presenting (A) versus non-presenting (B) twins. The secondary objectives were to determine if the CNM differed for 1) twin A and B among women with preterm labor (PTL) vs. preterm premature ruptured membranes (PPROM); 2) discordant (> 20%) vs. non-discordant (< 20%) twins. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Hector Mendez-Figueroa, Hind Moussa, Amy E. O'Neil, Joshua Dahlke, Suneet Chauhan Tags: Oral concurrent session 1 Source Type: research

19: Optimizing second stage outcomes: a randomized controled trial assessing the ability of precise maternal feedback to reduce adverse perinatal outcomes
Regional anesthesia reduces biofeedback impeding pushing efficacy during second stage labor. Long second stage is associated with adverse outcomes. We assessed the clinical impact of providing laboring women real-time audiovisual feedback regarding fetal descent during second stage. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Merlin Fausett, P. Barrilleaux, Jonnie Buford Tags: Oral concurrent session 2 Source Type: research

22: Metabolic acidemia at birth and risk of adverse neonatal outcomes in term pregnancies
Metabolic acidemia (MA) is considered to be in the putative pathway of hypoxic -ischemic organ injury including development of neonatal encephalopathy (NE). Our objective was to assess the association of MA with serious neonatal complications. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Sean Blackwell Tags: Oral concurrent session 2 Source Type: research

40: Duration of mechanical ventilation is an independent risk factor for cerebral palsy
Several antepartum and intrapartum risk factors are associated with cerebral palsy (CP); however, need and duration of neonatal mechanical ventilation (MV) may contribute to CP. One function of MV is to protect the brain from hypoxemia and asphyxia; however, MV use has been associated with adverse effects on the brain of a preterm infant. Currently, there is limited information regarding the duration of MV and incidence of CP; our objective, was to investigate this association. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Robyn Roberts, Nana-Ama Ankumah, Hector Mendez-Figueroa, Baha Sibai, Suneet Chauhan, Sean Blackwell Tags: Oral plenary session II Source Type: research

38: Outcomes of term induction in trial of labor after cesarean section (TOLAC) – analysis of a modern obstetric cohort
The primary objective of this study is to evaluate maternal and neonatal outcomes in women with 1 prior cesarean delivery undergoing induction of labor, compared with those who were expectantly managed, in a large, modern obstetric cohort. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Justin Lappen, David Hackney, Jennifer Bailit Tags: Oral plenary session II Source Type: research

53: Successful transnasal delivery of stem cells in a rat model of perinatal hypoxic-ischemic brain injury
New routes for cell transplantation into the brain need to be explored as intracerebral or intrathecal applications have a high risk to cause damage to the central nervous system. It has been hypothesized that transnasally administrated cells bypass the blood-brain barrier and migrate along the olfactory neural route into the brain and cerebrospinal fluid. Our goal is to confirm this hypothesis by transnasally administrating Wharton’s Jelly mesenchymal stem cells (WJ-MSC) and neural progenitor cells (NPC) to perinatal rats in a model of hypoxic-ischemic brain injury. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Byron Oppliger, Martin Müller, Marianne Jörger-Messerli, Ursula Reinhart, Andreina Schoeberlein, Daniel Surbek Tags: Oral concurrent session 5 Source Type: research

57: Alterations in the intestinal microbiome of infants are associated with breastfeeding practice
Cesarean delivery (CD) has been implicated in dysbiosis of the neonatal microbiome (totality of microbes and their genomes). However, it is possible that colinearity of CD with breastfeeding practice may confound these findings. Formula does not mimic the complexity of human breastmilk, which retains both macromolecules as well as a unique microbiome. We thus sought to employ a population-based cohort of mothers and their infants to determine if breastfeeding impacts the neonatal microbiome, potentially negating early cesarean-mediated dysbiosis. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Derrick Chu, Jun Ma, Amanda Prince, Kathleen Antony, Diana Racusin, Michelle Moller, Brigid Boggan, Kjersti Aagaard Tags: Oral concurrent session 5 Source Type: research

55: Neonatal complications in vacuum-assisted vaginal delivery: are they associated with number of pulls or cup dislodgement?
Although vacuum cup manufacturers suggest a maximum safe number of 3 pulls before proceeding with cesarean delivery, the effect of number of pulls on neonatal complications has not been explored. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Alessandro Ghidini, Daniel Stewart, Natazia Davidson, John Pezzullo Tags: Oral concurrent session 5 Source Type: research

61: Gomco versus mogen clamp circumcision: which is associated with less neonatal pain and stress? A randomized controlled trial: the GoMo study
Our objective is to compare pain/stress levels of newborns among the two most common circumcision techniques after resident-wide education. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Rachel Sinkey, Michaela Eschenbacher, Peggy Walsh, Rita Doerger, Donna Lambers, Baha Sibai, Mounira Habli Tags: Oral concurrent session 5 Source Type: research

60: Use of protease inhibitors in pregnancy is not associated with preterm birth or small for gestational age infants
Considering the conflicting data, as noted in the NIH perinatal guidelines, we sought to determine if the use of protease inhibitors (PI) in pregnancy is associated with preterm birth or small for gestational age infants. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Elaine Duryea, Fiona Nicholson, Sara Cooper, Scott Roberts, Vanessa Rogers, Donald McIntire, Jeanne Sheffield, Robert Stewart Tags: Oral concurrent session 5 Source Type: research

75: Twin birth study: incidence of caesarean delivery in induction of twin pregnancies
The Twin Birth Study demonstrated that in a planned vaginal birth between 32 and 38 weeks gestation in twin pregnancies where the first twin was a cephalic presentation, there was no difference in fetal and neonatal outcomes from a planned caesarean section. The Twin Birth Study necessitated an induction for women in the planned vaginal delivery group when completing 38 weeks of gestation. However, induction of labor can fail and lead to an unplanned caesarean delivery. The aim of this secondary analysis was to evaluate the incidence of factors which led to caesarean deliveries between the two approaches for induction, pro...
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Elad Mei-Dan, Elizabeth Asztalos, Andrew Willan, Alexander Allen, B. Anthony Armson, Amiram Gafni, Mary Hannah, Eileen Hutton, Ks Joseph, Arne Ohlsson, Susan Ross, Jon Barrett Tags: Oral concurrent session 7 Source Type: research

82: Detection of microbial invasion of the amniotic cavity by analysis of cervicovaginal proteins in preterm labor with intact membranes
Microbial invasion of the amniotic cavity (MIAC) is common in early preterm labor (PTL) and is associated with maternal and neonatal infectious morbidity. MIAC is often occult and is reliably detected only with amniocentesis. We sought to develop a noninvasive test to predict MIAC based on protein biomarkers in cervicovaginal fluid (CVF) in a cohort with PTL and to validate the test in an independent cohort. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: C Andrew Combs, Jodi Lapidus, Michael Gravett, Thomas Garite, Jerome Lapointe, ProteoGenix/Obstetrix Collaborative Research Network Tags: Oral concurrent session 8 Source Type: research

80: Impact of fetal gender on the risk of preterm birth
To study the influence of fetal gender on preterm birth and neonatal outcome in Caucasian women. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Myrthe Peelen, Brenda Kazemier, Anita Ravelli, Christianne de Groot, Petra Hajenius, Ben Mol, Marjolein Kok Tags: Oral concurrent session 8 Source Type: research

79: Metagenomics of a population-based prospective cohort reveals no discernable impact of mode of delivery (MOD) on the infant microbiome by 6 weeks of age
The infant microbiome is relatively sparse at birth, and populated early in life. The reported relative impact of MOD on the neonatal microbiome has garnered attention due to Cesarean (CD) prevalence and its association with later in life disease. Although previous small studies suggested that CD adversely impacted microbiome diversity, they were limited by potential confounding and lack of longitudinal sampling. We thus sought to interrogate whether MOD impacts the infant microbiome over time in a robust population-based cohort. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Derrick Chu, Jun Ma, Amanda Prince, Kathleen Antony, Michelle Moller, Brigid Boggan, Kjersti Aagaard Tags: Oral concurrent session 8 Source Type: research

86: Fetal and neonatal outcomes of non-primary cytomegalovirus maternal infection: a 13-year follow-up
To evaluate fetal and neonatal outcomes in case of non-primary cytomegalovirus (CMV) infection. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Giuliana Simonazzi, Francesca Cervi, Alessandra Curti, Chiara Puccetti, Sara Zagonari, Margherita Contoli, Tiziana Lazzarotto, Nicola Rizzo, Brunella Guerra Tags: Oral concurrent session 8 Source Type: research

83: Weight gain in pregnancy: does the IOM have it right?
We aimed to examine whether women who adhered to Institute of Medicine (IOM) recommendations for gestational weight gain had improved perinatal outcomes. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Yen Truong, Yvonne Cheng, Lynn Yee, Aaron Caughey Tags: Oral concurrent session 8 Source Type: research

92: Stillbirth in growth restricted twin pregnancies: when is the risk highest?
The optimal timing of the delivery of the twin fetus with growth restriction (FGR) remains a perinatal challenge. Our objective is to determine the gestation at which the risk for stillbirth (SB) is maximal. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Anthony Odibo, Amanda Trudell, Methodius Tuuli Tags: Poster session I Source Type: research

89: The pathway not taken: understanding ‘omics data in the perinatal context
Understanding 'omics data is important for perinatal research, but data analysis is challenging because most programs are curated for adult biology. Here we compared interpretation of fetal gene expression by Ingenuity Pathway Analysis (IPA) to Gene Set Enrichment Analysis (GSEA) with specific fetal functional annotation (Developmental FunctionaL Annotation at Tufts [DFLAT], http://dflat.cs.tufts.edu/). (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Andrea Edlow, Donna Slonim, Heather Wick, Lisa Hui, Diana Bianchi Tags: Poster session I Source Type: research

104: Altered amniotic fluid induces autophagy and cell death that leads to preterm birth after fetoscopic laser surgery (FLS) for twin-twin transfusion syndrome (TTTS)
Extreme prematurity after FLS for TTTS is associated with severe perinatal mortality and morbidity. We hypothesized that amniotic fluid (AF) alterations due to disease process prior to laser surgery induces autophagy and cell death in fetal membranes as a possible mechanism for extreme preterm delivery (EPD: (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Lovepreet Mann, Ramesha Papanna, Mi-Ae Lyu, Arshad Khan, Chinnaswamy Jagannath, Heinrich Taegtmeyer, Kenneth Moise, Anthony Johnson, Michael Bebbington Tags: Poster session I Source Type: research

102: Pregnancy complications are increased among women with cardiomyopathy compared to those with other cardiac diseases
In this study, we sought to identify perinatal outcomes in pregnant women with cardiomyopathy as compared to other types of cardiac disease. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Katherine Bianco, Ian Harris, Dana Henry, Molly Killion, Valerie Bosco, Mari-Paule Thiet, Juan Gonzalez Tags: Poster session I Source Type: research

110: Preterm premature rupture of membranes (PPROM) after fetoscopic laser surgery (FLS) for twin-twin transfusion syndrome (TTTS): risk factors and outcomes
FLS has increased perinatal survival for TTTS, but PPROM remains the main complication of the procedure. The natural history of PPROM after FLS and the associated factors have yet to be studied. Our objective was to determine the risk factors and outcomes of PPROM after FLS. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Saul Snowise, Lovepreet Mann, Kenneth Moise, Anthony Johnson, Michael Bebbington, Noemi Boring, Yisel Morales, Erin Canon, Genevieve Campbell, Ramesha Papanna Tags: Poster session I Source Type: research

123: Preexisting maternal depression confers increased risk of neonatal morbidity
To determine the relationship between maternal depression and adverse neonatal outcomes. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Amanda Yeaton-Massey, Teresa Sparks, Aaron Caughey Tags: Poster session I Source Type: research

132: Maternal height and risk for spontaneous preterm birth across BMI categories
Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality. Short stature and obesity have each been associated with increased risk for PTB. However, the effect of short height on PTB risk, across BMI categories has not been studied. Our objective was to determine the influence of maternal height on the risk for PTB within BMI categories. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Bat zion Shachar, Jonathan Mayo, Henry Lee, Gary Shaw, Jeffrey Gould Tags: Poster session I Source Type: research

137: Periventricular leukomalacia with PPROM: obstetric antecedents and infants’ outcomes
Verma et al (AJOG 1997) reported that periventricular leukomalacia (PVL), a known risk factor for neonatal morbidity, occurred in 8% (95% confidence interval [CI] 5-11%) of women with preterm premature rupture of membranes (PPROM). Our objective was to confirm the rate of PVL in contemporary practice and ascertain if it is linked with cerebral palsy (CP). (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Caroline Marrs, Hector Mendez-Figueroa, Suneet Chauhan Tags: Poster session I Source Type: research

133: Cardiovascular doppler assessments in IUGR: are they associated with adverse perinatal outcome? Results from the multicenter prospective PORTO trial
The objective of this analysis is to evaluate the relationship between cardiovascular Doppler assessments and perinatal outcome. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Breffini Anglim, Jennifer Walsh, Sean Daly, Julia Unterscheider, Michael Geary, Keelin O'Donoghue, Mairead Kennelly, Fionnuala McAuliffe, Alyson Hunter, John Morrison, Gerard Burke, Patrick Dicker, Elizabeth Tully, Fergal Malone Tags: Poster session I Source Type: research

139: Cord blood (CB) haptoglobin (Hp) switch-on as a biomarker of exposure to intra-uterine inflammation and adverse neonatal and childhood outcomes
In healthy term newborns Hp is absent at birth. Proteomics studies on CB led to the discovery that antenatal exposure to intra-uterine inflammation results in precocious “switch-on” of Hp (positive immunoreactivity on western blot). Here, we investigated the relationship between fetal Hp switch-on and childhood outcomes up to 2 years of life. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Catalin Buhimschi, Irina Buhimschi Tags: Poster session I Source Type: research

147: Immediate neonatal outcomes in infants exposed to magnesium sulfate at the time of delivery
Magnesium sulfate has proven to be beneficial for neuroprotection; however, there are conflicting reports on its effect on immediate neonatal resuscitation. The multicenter trial of magnesium sulfate for the prevention of cerebral palsy found no difference in immediate neonatal outcomes. Their analysis was performed by intent to treat and as such included patients that delivered with minimal magnesium exposure, after magnesium had been discontinued, or that delivered at term. Our objective was to determine whether exposure to magnesium sulfate at the time of delivery affects initial neonatal resuscitation. (Source: America...
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Daphnie Drassinower, Sarah Običan, Heather Levin, Cynthia Gyamfi-Bannerman Tags: Poster session I Source Type: research

151: Screening for fetal growth restriction (FGR) using universal third trimester ultrasonography: a prospective cohort study of 3,977 nulliparous women
To determine whether universal ultrasonographic screening of unselected nulliparous women for fetal growth restriction (FGR) could identify infants at increased risk of neonatal morbidity. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Ulla Sovio, Gordon Smith, Alison Dacey, Dharmintra Pasupathy, Ian White Tags: Poster session I Source Type: research

155: Ten year very low birth weight infant mortality/morbidity trends at a regional perinatal center: effect of perinatal and neonatal quality improvement program
Our hospital's incidence of VLBW infants ( (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Giancarlo Mari, Ramasubbareddy Dhanireddy Tags: Poster session I Source Type: research

156: Rupture in the scarred uterus
Uterine rupture is a devastating obstetrical complication associated with significant maternal & neonatal morbidity & mortality. Over the years, in relation to trial of labor after cesarean (TOLAC), research has focused on risk factors, but uterine rupture remains unpredictable. The role of oxytocin is still controversial & labor complications are poorly studied. Our goal here was to identify the main preceding factors contributing to rupture of the scarred uterus in a large population. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Gustavo Vilchez, Navleen Gill, Jing Dai, Anushka Chelliah, Helen Jaramillo, Robert Sokol Tags: Poster session I Source Type: research

159: Therapeutic N-acetyl-cysteine (NAC) following the initiation of maternal inflammation attenuates long term offspring cerebral injury evident by magnetic resonance imaging (MRI)
Maternal infection/inflammation may induce fetal inflammatory responses which have been associated with long term offspring cerebral injury. We previously demonstrated that prophylactic NAC, administered prior to and following maternal lipopolysaccharide (LPS), reduced cerebral injury evident on MRI. In the present study, we examined the effect of therapeutic NAC following maternal LPS-induced inflammation on neonatal brain injury as measured by MRI. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Hila Sharabi, Yuval Ginsberg, Nizar Khatib, Zeev Weiner, Michael Ross, Mordechai Hallak, Ron Beloosesky Tags: Poster session I Source Type: research

166: Episiotomies: who does them and do they help?
To examine episiotomy rates in relation to obstetric provider characteristics and maternal and neonatal injury. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Janet Burlingame, Chieko Kimata, Kelly Yamasato, Bruce Huegel, Marsha Durbin, Melinda Ashton Tags: Poster session I Source Type: research

173: A comparison of cervical cerclage and vaginal pessaries in the prevention of spontaneous preterm birth in women with a short cervix
Cervical cerclage and vaginal pessaries are both used as treatment strategies for the prevention of spontaneous preterm birth. Our objective was to compare pregnancy and neonatal outcomes in women who had either an ultrasound or exam-indicated cervical cerclage or a vaginal pessary placed for the treatment of a short cervix ( (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Katherine Scolari Childress, Amy Flick, Erin Dickert, Jeffrey Gavard, Ricardo Bolanos, Gilad Gross Tags: Poster session I Source Type: research

182: The risks of fetal and neonatal death in large-for-gestational age neonates: a population based study
To compare the risks of fetal death (FD) and neonatal death (ND) between 34 and 42 weeks gestational age (GA) in average-for-gestational age (AGA) and large-for-gestational age (LGA) pregnancies. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Lena Braginsky, Alicia Mandujano, Stephen Myers, Thaddeus Waters Tags: Poster session I Source Type: research

181: Recurrence rate of placental abruption: a longitudinal linked cohort study in the Netherlands
Placental abruption (PA) is associated with significant perinatal mortality and morbidity. Women who suffered PA have a risk of recurrence, but exact information to quantify this risk is currently not available. We studied the recurrence rate of placental abruption in a subsequent pregnancy. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Laura Ruiter, Anita Ravelli, Irene de Graaf, Ben Willem Mol, Eva Pajkrt Tags: Poster session I Source Type: research

189: Fetal growth restriction < 5% versus 5-9%: multi-center study for comparison of neonatal morbidity (ULTRA TOT)
While it is known that neonatal birth weight < 5% has greater morbidity than those at 5-9% for gestational age (GA), there is paucity of publications with fetal growth restriction (FGR) categorized according to sonographic estimated fetal weight (SEFW) < 5 vs. 5-9% for GA. Our objective was to determine if the composite neonatal morbidity (CNM) differed for FGR < 5% vs. 5-9%. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Malgorzata Mlynarczyk, Suneet Chauhan, Hind Baydoun, Catherine Wilkes, Kimberly Earhart, Christopher Goodier, Eugene Chang, Nicole Lee, E Kaitlyn Mize, Michelle Owens, Shilpa Babbar, Dev Maulik, Emily DeFranco, David McKinney, Alfred Abuhamad Tags: Poster session I Source Type: research

192: Optimal gestational age (GA) for delivery of twins with advanced maternal age (AMA)
Epidemiologic data suggests that delivery of a singleton gestation at 39wks minimizes fetal/infant mortality in women ≥40yrs.There is a paucity of data regarding the optimal timing of twin deliveries in women ≥40yrs.We sought to compare delivery outcomes for dichorionic/diamniotic(di/di) twin pregnancies who delivered at ≥34wks in women ≥40yrs compared to 34wks is associated with neonatal/maternal morbidity. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Maria Teresa Mella, Meredith Miller, Katherine Hrebinko, Keila Smilen, Chole Getradjman, Joanna Stone, Angela Bianco Tags: Poster session I Source Type: research

199: Does induction with misoprostol impact small for gestational age neonates?
To compare outcomes in small for gestational age (SGA) neonates induced with misoprostol to other cervical ripening agents. We hypothesized that misoprostol in pregnancies with SGA neonates will result in no significant differences in neonatal outcomes (NEO) compared to alternative agents such as other prostaglandins (PG), mechanical dilation and oxytocin. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Megan Foeller, Meredith Cruz, Michelle Kominiarek, Judith Hibbard Tags: Poster session I Source Type: research

198: A new model of pre-eclampsia in rats designed by MRI to assess perinatal outcomes
The physiopathology of pre-eclampsia (PE) begins with placental hypoxia followed by an ill-defined maternal aberrant inflammatory response. The classical RUPP model (Reduced Uterine Perfusion Pressure) creates severe uterine hypoxia and prevents long-term evaluation of pups. Furthermore, metallic clips used in this model prevent evaluation by MRI. We propose to use adapted rodent RUPP models in which the clips used are replaced by surgical sutures. Our objective is to develop and characterize (by MRI) modified models of RUPP which will reproduce varying degrees of PE. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Maxime Godmaire, Simon Blouin, Lisette Haddad, Krystel Paris, Jean-Charles Pasquier Tags: Poster session I Source Type: research

205: Extreme obesity and neonatal outcomes in the MFMU cesarean registry
To investigate the association between maternal obesity and neonatal outcomes in cesarean deliveries. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Morgan Kearney, Marcela Smid, David Stamilio Tags: Poster session I Source Type: research

201: Prevalence of prior gastric bypass surgery among obese pregnant women and associated adverse pregnancy outcomes
To evaluate whether a prior gastric bypass is associated with adverse perinatal outcomes. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Meiling Hua, Vincenzo Berghella, Jugnu Nijjar Tags: Poster session I Source Type: research

214: Late entrants to prenatal care: a predictor of infant mortality?
To examine the risk of neonatal and infant death in women who present late to prenatal care. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Rachel Pilliod, Leah Savitsky, Allison Allen, Jennifer Katz Eriksen, Aaron Caughey Tags: Poster session I Source Type: research

226: Prenatal detection of congenital heart disease
Prenatal detection of major congenital heart disease (CHD) improves neonatal survival and reduces morbidity. NHS guidelines suggest a minimum standard with a target of at least 50% of such lesions being detected prenatally. Our objective was to evaluate the precision of prenatal diagnosis of CHD at a single tertiary referral unit (of approximately 8,500 deliveries per year) over a six-year period (2006-2012), encompassing 51,822 deliveries during this time. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Siobhan Corcoran, Kaleigh Briggs, Hugh O' Connor, Siglinde Muellers, Cathy Monteith, Jennifer Donnelly, Patrick Dicker, Orla Franklin, Fergal Malone, Fionnuala Breathnach Tags: Poster session I Source Type: research

230: Maternal-neonatal transfer of preoperative cefazolin at cesarean section (C/S)
ACOG currently recommends a single dose of antibiotic prophylaxis prior to all C/S. This recommendation is based on pharmacokinetic (PK) studies which include only non-obese patients. Cefazolin is commonly used despite Enterococcus, E. Coli and Klebsiella resistance. We sought to evaluate 1) Cefazolin pharmacokinetics for obese and non-obese patients following administration of a single 2g dose for prevention of wound infections, and 2) whether umbilical cord blood (UCB) levels of Cefazolin may be protective against possible pathogens causing early onset neonatal sepsis. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Stephanie McKenney, Azadeh Farzin, Samuel Yang, Jamie Murphy, Mark Marzinke, Carlton Lee, Irina Burd Tags: Poster session I Source Type: research

227: Fetal growth restriction co-existing with gestational diabetes – impact on perinatal outcome: results of the multicenter PORTO study
The incidence of Fetal Growth Restriction(FGR) is similar for patients with gestational diabetes (GDM) as it is for healthy non-diabetic pregnant patients.There are little data available on the outcome of pregnancies complicated by GDM coexisting with FGR. We sought to examine FGR in gestational diabetics and to determine perinatal outcome. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Siobhan Corcoran, Julia Unterscheider, Sean Daly, Michael Geary, Mairead Kennelly, Fionnuala McAuliffe, Keelin O'Donoghue, Alyson Hunter, John Morrison, Gerard Burke, Patrick Dicker, Elizabeth Tully, Fergal Malone Tags: Poster session I Source Type: research

235: Structural congenital hearth disease (CHD) in neonates delivered to women with CHD: results from the national perinatal research consortium (NPRC) registry for adverse rare events (RARE)
To describe factors associated with the diagnosis of structural CHD among neonates delivered to women with structural CHD. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Tracy Manuck, Zachary Rubeo, Victoria Jauk, Kelli Barbour, Fara Behnia, Joseph Biggio, Michelle DiVito, Karen Dorman, Miaoying Fan, Christine Horton, Maggie Joe Kuhlmann, Rachel LeDuke, Laurie Lesher, George Saade, Ashley Salazar, Shanna Salmon, Alison St Tags: Poster session I Source Type: research

233: Cannabis in pregnancy: legal, but safe?
Cannabis use in the United States is common, though data on its effects in pregnancy are limited. As more states move to decriminalize cannabis, the importance of accurate data on risks associated with cannabis use in pregnancy grows. We evaluated maternal and neonatal outcomes in pregnancies exposed to cannabis. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 19, 2014 Category: OBGYN Authors: Teresa Worstell, Margaret Gorman, Aaron Caughey Tags: Poster session I Source Type: research