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This page shows you the most recent publications within this specialty of the MedWorm directory.

Association between preterm birth and thoracic musculoskeletal static alterations in adolescents
CONCLUSION: Adolescents born prematurely presented greater thoracic musculoskeletal static alterations compared to those born at term. Factors associated with these alterations were: very low birth weight and longer duration of mechanical ventilation in the neonatal unit. (Source: Revista Brasileira de Fisioterapia)
Source: Revista Brasileira de Fisioterapia - March 1, 2015 Category: Physiotherapy Source Type: research

Intrauterine growth retardation in foetuses of women with epilepsy
Conclusion Impaired intrauterine growth of foetuses in women with epilepsy was identified. The frequency of SGA and low ponderal index was highest in Lamotrigine exposed infants. The epilepsy group had a higher risk profile for having smaller babies, in being younger at age, lower in body weight and more frequent smokers. However despite these differences, the effects of epilepsy and AED exposure were significant. The ponderal index may be a useful supplement to more established measures assessing intrauterine growth in epilepsy. (Source: Seizure)
Source: Seizure - March 1, 2015 Category: Neurology Source Type: research

A Reason to Celebrate!
This year marks the 50th anniversary of the nurse practitioner (NP) profession. A shortage of pediatricians to serve in rural areas prompted both Dr. Loretta Ford and Dr. Henry Silver to envision a new level of nurse who could provide pediatric primary care for those most in need. Their collaboration as nurse and physician resulted in the development of the Pediatric NP Program in Colorado. From that initial program, the profession has blossomed into several other programs, specifically family, acute care, women’s health, neonatal, psychiatric, and adult/gerontological. (Source: The Journal for Nurse Practitioners)
Source: The Journal for Nurse Practitioners - March 1, 2015 Category: Nursing Authors: Kenneth P. Miller Tags: From the AANP President Source Type: research

Preconception Care: Planning for the Future
In the United States, rates of maternal mortality, unplanned pregnancies, low birthweight infants, and preterm infants continue to rise, making the need for preconception care a priority in the delivery of care. Traditionally, women have viewed preconception care as a single visit made before attempting pregnancy; however, the maximum benefits are obtained when the woman and her partner receive care throughout the reproductive years, whether pregnancy is immediately planned or not. The primary care nurse practitioner has a pivotal role in the identification of risk factors and encouragement of healthy behaviors that have t...
Source: The Journal for Nurse Practitioners - March 1, 2015 Category: Nursing Authors: Helen M. Hurst, Denise M. Linton Tags: Feature Article Source Type: research

Very long apnea events in preterm infants
We describe here very long (>60 s) central apnea events (VLAs) with bradycardia and desaturation, discovered using a computerized detection system applied to our database of over 100 infant years of electronic signals. Eighty-six VLAs occurred in 29 out of 335 VLBW infants. Eighteen of the 29 infants had a clinical event or condition possibly related to the VLA. Most VLAs occurred while infants were on nasal continuous positive airway pressure, supplemental oxygen, and caffeine. Apnea alarms on the bedside monitor activated in 66% of events, on average 28 s after cessation of breathing. Bradycardia alarms activated late...
Source: Journal of Applied Physiology - March 1, 2015 Category: Physiology Authors: Mohr, M. A., Vergales, B. D., Lee, H., Clark, M. T., Lake, D. E., Mennen, A. C., Kattwinkel, J., Sinkin, R. A., Moorman, J. R., Fairchild, K. D., Delos, J. B. Tags: ARTICLES Source Type: research

Development of a 12month screener based on items from the Bayley II Scales of Infant Development for use in Low Middle Income countries
The purpose of the current study was to adapt the Bayley Scales of Infant Development II for use as a screening measure that could be used by health care professionals in Low Middle Income (LMI) countries with 12month old infants to determine if they needed further assessment and early intervention. (Source: Early Human Development)
Source: Early Human Development - February 28, 2015 Category: Perinatology & Neonatology Authors: Fred J. Biasini, Desiree De Jong, Sarah Ryan, Vanessa Thorsten, Carla Bann, Roopa Bellad, Niranjana S. Mahantshetti, Sangappa M. Dhaded, Omrana Pasha, Elwyn Chomba, Shivaprasad S. Goudar, Waldemar A. Carlo, Elizabeth McClure Source Type: research

Newborn survives rare heart transplant surgery
Baby Oliver had a major heart defect when he was born seven weeks premature, but he got a second chance (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - February 28, 2015 Category: Consumer Health News Source Type: news

Six-day old newborn survives rare heart surgery
Baby Oliver may be the youngest heart transplant recipient ever. He was born seven weeks premature at Phoenix Children's Hospital with a bad heart. Doctors feared for the worst, but the baby survived the surgery. Carter Evans reports. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - February 28, 2015 Category: Consumer Health News Source Type: news

N-acetylcysteine effectively diminished meconium-induced oxidative stress in adult rabbits.
Authors: Mokra D, Drgova A, Mokry J, Antosova M, Durdik P, Calkovska A Abstract Since inflammation and oxidative stress are fundamental in the pathophysiology of neonatal meconium aspiration syndrome (MAS), various anti-inflammatory drugs have been used in experimental and clinical studies on MAS. This pilot study evaluated therapeutic potential of N-acetylcysteine in modulation of meconium-induced inflammation and oxidative lung injury. Oxygen-ventilated adult rabbits were intratracheally given 4 ml/kg of meconium (25 mg/ml) or saline (Sal, n = 6). Thirty minutes later, meconium-instilled animals were treated with...
Source: Journal of Physiology and Pharmacology - February 28, 2015 Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research

Neonatal sepsis caused by Shewanella algae: A case report
We report a case of S. algae blood stream infection in a newborn with early onset neonatal sepsis. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - February 28, 2015 Category: Journals (General) Source Type: research

Use of Selective Serotonin Reuptake Inhibitor Antidepressants in Pregnancy Does Carry Risks, but the Risks Are Small
Abstract: The paper by Robinson posits that risks from prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants are not different from the risks encountered in the general population and that untoward effects of SSRIs are difficult to distinguish from those of the mood disorder. Indeed, maternal depression and anxiety can have negative consequences for fetal and postnatal development. Fortunately, experimental evidence suggests that mood and anxiety disorder symptoms often respond to psychosocial interventions. If pharmacotherapy becomes necessary, it is, however, important to know that even if SS...
Source: The Journal of Nervous and Mental Disease - February 28, 2015 Category: Psychiatry Tags: Clinical Controversies Source Type: research

Controversies About the Use of Antidepressants in Pregnancy
Abstract: There is controversy about the use of antidepressant medication during pregnancy. Decisions about their use are affected by understanding the risks of these medications causing pregnancy loss, congenital malformations, neonatal adaptation syndrome, persistent pulmonary hypertension of the newborn, autism spectrum disorder, or long-term neurocognitive deficits. Although some research has raised concerns about antidepressants causing harm to the fetus and neonate, other studies have disputed these findings or noted that any risks found do not exceed the risk of congenital problems found in 1% to 3% of neonates in t...
Source: The Journal of Nervous and Mental Disease - February 28, 2015 Category: Psychiatry Tags: Clinical Controversies Source Type: research

New phenotype and neonatal onset of sodium channel myotonia in a child with a novel mutation of gene
We reported a 4-year-old female who presented with diffuse stiffness, bilateral clubfoot, hip dislocation, facial dysmorphisms and myotonia at birth. At 4years of age the neurological examination showed characteristic “Hercules-like appearance” hyporeflexia, mild grip myotonia and bilateral pes cavus. The stiffness was worst at rest and in the early morning which improves with exercise. (Source: Brain and Development)
Source: Brain and Development - February 28, 2015 Category: Neurology Authors: Carlo Fusco, Daniele Frattini, Grazia Gabriella Salerno, Elena Canali, Pia Bernasconi, Lorenzo Maggi Tags: Case Report Source Type: research

Discordance in fetal biometry and doppler are independent predictors of the risk of perinatal loss in twin pregnancies
Discordance in estimated fetal weight and cerebroplacental ratio are independent predictors of the risk of perinatal loss in twin pregnancies. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - February 28, 2015 Category: OBGYN Authors: Asma A. Khalil, Naila Khan, Sophie Bowe, Alessandra Familiari, Aris Papageorghiou, Amar Bhide, Basky Thilaganathan Source Type: research

The argument for operative approach to asymptomatic lung lesions
Antenatal detection of Congenital Pulmonary Airway Malformations (CPAM) has improved immeasurably from its initial application in the 1980s and probably encompasses >80% of all such lesions. Accurate diagnosis still remains less reliable and definitive diagnosis requires detailed anatomical imaging (typically with CT scan) in the post-natal period. About 10% of all lesions will present with symptoms during the neonatal period and the choice of surgical intervention is then easy. For those that remain asymptomatic then there is still a degree of controversy about elective surgical resection. (Source: Seminars in Pediatric Surgery)
Source: Seminars in Pediatric Surgery - February 28, 2015 Category: Pediatrics Authors: Rashmi Singh, Mark Davenport Tags: #7 Source Type: research

The pathology of congenital lung lesions
The spectrum of complications associated with congenital lung malformation is wide. They can range from fetal hydrops in utero to postnatal problems of ventilation, obstruction and infection; presentation may occur from the neonatal period to adulthood. Many lesions will remain asymptomatic while at the other end of the complication spectrum, there is a small risk of neoplasia associated with some forms of cystic lung. A better understanding of the pathology has shown that bronchial atresia / obstruction is the likely hidden pathology underlying many congenital lung lesions leading to downstream cystic maldevelopment. (Sou...
Source: Seminars in Pediatric Surgery - February 28, 2015 Category: Pediatrics Authors: Darren Fowler, Steve Gould Source Type: research

Environmental stimulation improves performance in the ox-maze task and recovers Na+,K+-ATPase activity in the hippocampus of hypoxic–ischemic rats
In conclusion, EE was effective in recovering learning and memory impairment in the ox-maze task and Na+,K+-ATPase activity in the hippocampus caused by HI. The present data provide further support for the therapeutic potential of environmental stimulation after neonatal HI in rats. (Source: Neuroscience)
Source: Neuroscience - February 28, 2015 Category: Neuroscience Source Type: research

Neonatal Outcomes after Oral Administration of Antenatal Corticosteroid: A Case Report
Publication date: Available online 27 February 2015 Source:Saudi Pharmaceutical Journal Author(s): Doua AlSaad , Palli Valapila Abdulrouf , Hussain Parappil , Asma Tarannum , Binny Thomas The use of antenatal corticosteroids is associated with reduction in morbidity and mortality rates in preterm delivery. A 34 year-old pregnant woman, gravida 2 para1, was planned for elective cesarean section at 36 weeks of gestation as ultrasound study showed intrauterine growth retardation. She has idiopathic thrombocytopenia and anemia, with suspected hypoplastic anemia. Due to mother’s low platelet count, antenatal intramuscular c...
Source: Saudi Pharmaceutical Journal - February 28, 2015 Category: Drugs & Pharmacology Source Type: research

Predictors of Unfavorable Thermal Outcome During Newborn Emergency Retrievals
Conclusion Abnormal temperature at the start of the retrieval, very low transport weight, and respiratory support were strong predictors of unfavorable thermal outcome during neonatal emergency transports. (Source: Air Medical Journal)
Source: Air Medical Journal - February 28, 2015 Category: Emergency Medicine Source Type: research

Intramuscolar epinephrine during neonatal resuscitation
Nicoletta Doglioni wrote the first draft of the manuscript, non honorarium, grant, or other form of payment was given to anyone to produce the manuscript. (Source: Resuscitation)
Source: Resuscitation - February 28, 2015 Category: Emergency Medicine Authors: Nicoletta Doglioni, Lino Chiandetti, Daniele Trevisanuto Tags: Letter to the Editor Source Type: research

Correlation between veno-venous anastomoses, TTTS and perinatal mortality in monochorionic twin pregnancies
The clinical significance of veno-venous (VV) anastomoses in monochorionic (MC) placentas remains inconclusive and controversial. The purpose of this study was to investigate the correlation between the presence of VV anastomoses and clinical outcome in a large cohort of MC twin pregnancies. (Source: Placenta)
Source: Placenta - February 28, 2015 Category: Reproduction Medicine Authors: S.F. de Villiers, D.P. Zhao, D. Cohen, E.W. van Zwet, T. Duan, D. Oepkes, E. Lopriore Source Type: research

South Africa: Curbing Maternal Deaths High On KZN's Priorities
[SAnews.gov.za]Pretoria -The reduction of maternal, neonatal and child mortality will be the focus for the KwaZulu-Natal Provincial Government over the next five years. (Source: AllAfrica News: Pregnancy and Childbirth)
Source: AllAfrica News: Pregnancy and Childbirth - February 27, 2015 Category: OBGYN Source Type: news

“Can I Ask That?”: Perspectives on Perinatal Care After Resettlement Among Karen Refugee Women, Medical Providers, and Community-Based Doulas
This study characterized the perspectives of Karen refugee women in Buffalo, NY, their medical providers, and Karen interpreters/doulas on perinatal care for Karen women in resettlement. In-depth qualitative interviews with Karen women (14), Karen doulas/interpreters and key informants (8), and medical providers (6) were informed by the social contextual model and focused on women’s questions about and opinions of perinatal care in Buffalo and on providers’ experiences caring for Karen patients. Karen women expressed gratitude for and understanding of perinatal care in Buffalo, and providers described Karen patients as...
Source: Journal of Immigrant and Minority Health - February 27, 2015 Category: Global & Universal Source Type: research

[Correspondence] Post-partum depressive episodes and bipolar disorder
With great interest, we read the Lancet Series on perinatal health. Louise Howard and colleagues' Series paper1 discussed non-psychotic mental disorders in the perinatal period. In the second paper of the Series, Ian Jones and colleagues2 provided a comprehensive overview of post-partum psychotic episodes occurring in the context of bipolar disorder or schizophrenia. Although Howard and colleagues1 methodically reviewed non-psychotic disorders, including major depressive disorder occurring during the perinatal period, an important topic that is not addressed is post-partum depression arising from an underlying bipolar diso...
Source: LANCET - February 27, 2015 Category: Journals (General) Authors: Mustaq Khan, Verinder Sharma Tags: Correspondence Source Type: research

Why Is Initial Bacterial Colonization of the Intestine Important to Infants' and Children's Health?
ABSTRACT: Microbial colonization of the infant occurs during a critical time window for immune and gastrointestinal development. Infant colonization sets the stage for the adult microbiome. This review is a broad survey of the factors affecting infant colonization and the downstream effects on gastrointestinal health and disease. Major topics affecting colonization include initial inoculation dependent on birth mode, the impact of breast-feeding, and inside-out modulation of the developing microbiome by the immune system. Major outcomes of colonization include the timing-dependent education of the neonatal immune system, w...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 27, 2015 Category: Gastroenterology Tags: Invited Review Source Type: research

Birth order and risk of hepatocellular carcinoma in chronic carriers of hepatitis B virus: a case‐control study in The Gambia
ConclusionsCompared to controls, HCC cases had earlier birth order, a proxy for young maternal age and maternal HBV viraemia at birth. This finding suggests that in chronic HBV carriers perinatal mother‐to‐infant transmission may increase HCC risk more than horizontal transmission. Providing HBV vaccine within 24 hours of birth to interrupt perinatal transmission might reduce the incidence of HCC in The Gambia.This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - February 27, 2015 Category: Gastroenterology Authors: Yusuke Shimakawa, Maud Lemoine, Christian Bottomley, Harr Freeya Njai, Gibril Ndow, Abdoulie Jatta, Saydiba Tamba, Lamin Bojang, Makie Taal, Ousman Nyan, Umberto D'Alessandro, Ramou Njie, Mark Thursz, Andrew J. Hall Tags: Original Article Source Type: research

Placental pathology in smoking and non-smoking preeclamptic women
The Journal of Maternal-Fetal & Neonatal Medicine, Ahead of Print. (Source: Journal of Maternal-Fetal and Neonatal Medicine)
Source: Journal of Maternal-Fetal and Neonatal Medicine - February 27, 2015 Category: Perinatology & Neonatology Tags: article Source Type: research

Prenatal Diagnosis and Treatment of Spina Bifida
Fetal Diagn Ther 2015;37:161 (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - February 27, 2015 Category: Perinatology & Neonatology Source Type: research

Ultrasound Assessment of Umbilical Cord Morphology in the First Trimester: A Feasibility Study
Conclusions: Umbilical cord morphology can be consistently studied in the first trimester. A subjective method of evaluation of the morphology may be a more reproducible technique until measurement strategies are refined and operator experience developed.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - February 27, 2015 Category: Perinatology & Neonatology Source Type: research

Scottish ministers announce review of maternity and neonatal services
The Scottish Government has announced a “refresh” of its policies on maternity and neonatal services to ensure “every mother and baby continues to get the best possible care”. (Source: Nursing Times Breaking News)
Source: Nursing Times Breaking News - February 27, 2015 Category: Nursing Source Type: news

Placental vitamin D receptor expression is decreased in human idiopathic fetal growth restriction
Abstract Fetal growth restriction (FGR) affects up to 5 % of pregnancies worldwide, and trophoblast function plays a significant role on the outcome. An epidemiological study has linked vitamin D deficiency to adverse perinatal outcomes, which include decreased birth weight. The placenta as an important source of vitamin D regulates its metabolism through the vitamin D receptor (VDR), but the mechanism by which VDR regulates trophoblast function is poorly understood. Our study aimed at determining placental VDR expression in FGR and gestation-matched control (GMC) pregnancies and identifying the actions of VDR i...
Source: Journal of Molecular Medicine - February 27, 2015 Category: Molecular Biology Source Type: research

Inhibition of MAPK/ERK signaling blocks hippocampal neurogenesis and impairs cognitive performance in prenatally infected neonatal rats
Abstract Hippocampus endogenous neurogenesis has been postulated to play a favorable role in brain restoration after injury. However, the underlying molecular mechanisms have been insufficiently deciphered. Here we investigated the potential regulatory capacity of MAPK/ERK signaling on neurogenesis and the associated cognitive performance in prenatally infected neonatal rats. From our data, intrauterine infection could induce hippocampal neuronal apoptosis and promote endogenous repair by evoking neural stem cell proliferation and survival. We also found intrauterine infection could induce increased levels of ...
Source: European Archives of Psychiatry and Clinical Neuroscience - February 27, 2015 Category: Neuroscience Source Type: research

Lung function following very preterm birth in the era of ‘new’ bronchopulmonary dysplasia
Abstract One of the most significant complications of preterm birth is bronchopulmonary dysplasia (BPD). The pathophysiology of BPD has changed in recent years as advances in neonatal care have led to increased survival of smaller, more preterm, infants who display alterations to alveolar and pulmonary microvascular development. It is becoming clear that infants with ‘new’ BPD experience lung disease that persists into later childhood, however, the oldest of these children are just now entering young adulthood and therefore the longer term pulmonary implications remain unknown. The role of lung function testing in the ...
Source: Respirology - February 27, 2015 Category: Respiratory Medicine Authors: Shannon J. Simpson, Graham L. Hall, Andrew C. Wilson Tags: Invited Review Series: Respiratory Disease: Using Lung Function Measurements to Greater Advantage Source Type: research

Obstetric and neonatal outcome of multifetal pregnancy reduction
Conclusion MFPR procedure seems to be good and acceptable option for patients with HOMP but not totally safe. (Source: Middle East Fertility Society Journal)
Source: Middle East Fertility Society Journal - February 27, 2015 Category: Reproduction Medicine Source Type: research

Porcine epidemic diarrhea virus infection: etiology, epidemiology, pathogenesis and immunoprophylaxis
Publication date: Available online 26 February 2015 Source:The Veterinary Journal Author(s): Kwonil Jung , Linda J. Saif Porcine epidemic diarrhea virus (PEDV), a member of the genera Alphacoronavirus in the family Coronaviridae, causes acute diarrhea/vomiting, dehydration and high mortality in seronegative neonatal piglets. For the last three decades, PEDV infection has resulted in significant economic losses in the European and Asian pig industries, but in 2013-2014 the disease was also reported in the US, Canada and Mexico. The PED epidemic in the US, from April 2013 to the present, has led to the loss of more than 10...
Source: The Veterinary Journal - February 27, 2015 Category: Veterinary Research Source Type: research

Analytic Characteristics of Three Bayer Contour Blood Glucose Monitoring Systems in Neonates
Hypoglycemia in infants is common, is difficult to recognize, and may lead to permanent neurologic impairment. Low glucose concentrations and high hematocrits in newborns pose significant analytic challenges for whole blood glucose meters. Three Bayer glucose monitoring systems were evaluated using 211 blood samples from 162 neonates (age range 5 hours to 29 days, median age 3 days). Hematocrit and whole blood glucose were determined in heparinized whole blood, and plasma glucose was determined using the Roche Cobas® 6000. Accuracy was evaluated against plasma concentrations using ISO 15197:2013 and CLSI POCT 12-A3 cri...
Source: Journal of Diabetes Science and Technology - February 27, 2015 Category: Endocrinology Authors: Dietzen, D. J., Nenninger, D. A., Simmons, D. A., Pardo, S., Pandya, M., Fullam, J. Tags: Original Articles Source Type: research

Review Article: Role of methylxanthines in preventing acute renal failure in hypoxic newborns
Publication date: Available online 26 February 2015 Source:Apollo Medicine Author(s): Kiran P. Sathe , Anjali Kulkarni Background Acute renal failure secondary to perinatal asphyxia is a serious & common problem in developing countries due to lack of appropriate delivery facilities. Under hypoxic conditions, there is an excess of adenosine production, which by its virtue of renal vasoconstriction serves to reduce the glomerular filtration rate. Studies have reported beneficial role of adenosine blockade by methylxanthines in preventing acute oliguric renal failure in hypoxic neonates. Methods We reviewed the ava...
Source: Apollo Medicine - February 27, 2015 Category: Journals (General) Source Type: research

Current Resources for Evidence‐Based Practice, March/April 2015
(Source: Journal of Obstetric, Gynecologic, and Neonatal Nursing)
Source: Journal of Obstetric, Gynecologic, and Neonatal Nursing - February 27, 2015 Category: Nursing Authors: Nicole S. Carlson Tags: Special Report Source Type: research

Preferences for infant delivery site among pregnant women and new mothers in Northern Karnataka, India
Conclusions: In the literature, quality of care beyond access has largely been overlooked in favour of support for incentives on the demand side, and more trained doctors, facilities and equipment on the supply side. Taking a comprehensive approach to quality of care in line with cultural values and community needs is imperative for improving experiences, utilization, and ultimately maternal and neonatal health outcomes at the time of delivery. (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - February 27, 2015 Category: OBGYN Authors: Sharon BruceAndrea BlanchardKaveri GuravAnuradha RoyKrishnamurthy JayannaHaranahalli MohanBanadakoppa RameshJames BlanchardStephen MosesLisa Avery Source Type: research

Maternal psychological distress and visitation to the neonatal intensive care unit
ConclusionDistress is an important predictor of visitation. In turn, visitation is associated with long‐term maternal distress. (Source: Acta Paediatrica)
Source: Acta Paediatrica - February 27, 2015 Category: Pediatrics Authors: Michelle M. Greene, Beverly Rossman, Kousiki Patra, Amanda Kratovil, Samah Khan, Paula P. Meier Tags: Regular Article Source Type: research

Methods of milk expression for lactating women.
CONCLUSIONS: The most suitable method for milk expression may depend on the time since birth, purpose of expression and the individual mother and infant. Low-cost interventions including early initiation when not feeding at the breast, listening to relaxation music, massage and warming of the breasts, hand expression and lower cost pumps may be as effective, or more effective, than large electric pumps for some outcomes. Small sample sizes, large standard deviations, and the diversity of the interventions argue caution in applying these results beyond the specific method tested in the specific settings. PMID: 25722103 ...
Source: Cochrane Database of Systematic Reviews - February 27, 2015 Category: Journals (General) Authors: Becker GE, Smith HA, Cooney F Tags: Cochrane Database Syst Rev Source Type: research

Ensemble of trees approaches to risk adjustment for evaluating a hospital’s performance
Abstract A commonly used method for evaluating a hospital’s performance on an outcome is to compare the hospital’s observed outcome rate to the hospital’s expected outcome rate given its patient (case) mix and service. The process of calculating the hospital’s expected outcome rate given its patient mix and service is called risk adjustment (Iezzoni 1997). Risk adjustment is critical for accurately evaluating and comparing hospitals’ performances since we would not want to unfairly penalize a hospital just because it treats sicker ...
Source: Health Care Management Science - February 26, 2015 Category: Health Management Source Type: research

Semi-quantitative Assessment of Brain Maturation by Conventional Magnetic Resonance Imaging in Neonates with Clinically Mild Hypoxic-ischemic Encephalopathy.
CONCLUSIONS: The TMS system, based on conventional MRI, is an effective method to detect delayed brain maturation in clinically mild HIE. The conventional MRI can reveal the different retardations in subtle structures and development processes among the different patterns of mild HIE. PMID: 25698186 [PubMed - in process] (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - February 26, 2015 Category: Journals (General) Authors: Gao J, Sun QL, Zhang YM, Li YY, Li H, Hou X, Yu BL, Zhou XH, Yang J Tags: Chin Med J (Engl) Source Type: research

A case with neonatal hyperinsulinemic hypoglycemia: It is a characteristic complication of sotos syndrome
In conclusion, our patient supported that HIH could be one of the characteristic symptoms of SoS in the neonatal period, and could be useful for early diagnosis. © 2015 Wiley Periodicals, Inc. (Source: American Journal of Medical Genetics Part A)
Source: American Journal of Medical Genetics Part A - February 26, 2015 Category: Genetics & Stem Cells Authors: Yoshie Nakamura, Masaki Takagi, Hiroshi Yoshihashi, Masaru Miura, Satoshi Narumi, Tomonobu Hasegawa, Yoshishige Miyake, Yukihiro Hasegawa Tags: Research Article Source Type: research

Perinatal mental health service provision in Switzerland and in the UK.
CONCLUSIONS: The main difference between the UK and Switzerland was the absence of guidelines, regular assessment and plans for future development of perinatal psychiatry in Switzerland. There are still geographical differences in the provision of perinatal-psychiatric services in the UK. PMID: 25701656 [PubMed - in process] (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - February 26, 2015 Category: Journals (General) Authors: Amiel Castro RT, Schroeder K, Pinard C, Blöchlinger P, Künzli H, Riecher-Rössler A, Kammerer M Tags: Swiss Med Wkly Source Type: research

Weight gain in pregnancy: does the Institute of Medicine have it right?
We aimed to examine whether women who adhered to Institute of Medicine (IOM) guidelines for gestational weight gain (GWG) had improved perinatal outcomes. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - February 26, 2015 Category: OBGYN Authors: Yen N. Truong, Lynn M. Yee, Aaron B. Caughey, Yvonne W. Cheng Tags: Research Source Type: research

Vitamin C supplementation ameliorates the adverse effects of nicotine on placental hemodynamics and histology in nonhuman primates
This study utilizes noninvasive imaging techniques and histological analysis in a nonhuman primate model to test the hypothesis that prenatal nicotine exposure adversely effects placental hemodynamics and development but is ameliorated by vitamin C. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - February 26, 2015 Category: OBGYN Authors: Jamie O. Lo, Matthias C. Schabel, Victoria H.J. Roberts, Terry K. Morgan, Juha P. Rasanen, Christopher D. Kroenke, Sophie R. Shoemaker, Eliot R. Spindel, Antonio E. Frias Tags: Research Source Type: research

Clinical Value of Maternal Bile Acid Quantification in Intrahepatic Cholestasis of Pregnancy as an Adverse Perinatal Outcome Predictor
Conclusions: ICP patients have higher rates of adverse neonatal outcomes when compared to those with gestational pruritus. Some of this neonatal morbidity may be secondary to late spontaneous preterm deliveries, multiple gestation and a policy of elective induction of labour after 37 weeks of gestation. A comparison of outcomes among patients with mild and severe ICP shows that the severely affected group has higher rates of meconium-stained amniotic fluid and neonatal morbidity.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - February 26, 2015 Category: OBGYN Source Type: research

Remission of Severe Neonatal Diabetes With Very Early Sulfonylurea Treatment.
PMID: 25715421 [PubMed - as supplied by publisher] (Source: Diabetes Care)
Source: Diabetes Care - February 26, 2015 Category: Endocrinology Authors: Marshall BA, Green RP, Wambach J, White NH, Remedi MS, Nichols CG Tags: Diabetes Care Source Type: research