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This page shows you the most recent publications within this specialty of the MedWorm directory.
Accumulation of GABAergic Neurons, Causing a Focal Ambient GABA Gradient, and Downregulation of KCC2 Are Induced During Microgyrus Formation in a Mouse Model of Polymicrogyria
Although focal cortical malformations are considered neuronal migration disorders, their formation mechanisms remain unknown. We addressed how the -aminobutyric acid (GABA)ergic system affects the GABAergic and glutamatergic neuronal migration underlying such malformations. A focal freeze-lesion (FFL) of the postnatal day zero (P0) glutamic acid decarboxylase–green fluorescent protein knock-in mouse neocortex produced a 3- or 4-layered microgyrus at P7. GABAergic interneurons accumulated around the necrosis including the superficial region during microgyrus formation at P4, whereas E17.5-born, Cux1-positive pyramidal...
Source: Cerebral Cortex - March 10, 2014 Category: Neurology Authors: Wang, T., Kumada, T., Morishima, T., Iwata, S., Kaneko, T., Yanagawa, Y., Yoshida, S., Fukuda, A. Tags: Articles Source Type: research
Intrauterine growth restriction modifies gene expressionprofiling in cord blood
ConclusionsExpression of certain genes was modified in SGA newborns in the fetal period.These genes have been associated with metabolic syndrome.To clarify the association between modified gene expression incord blood and individual vulnerability to metabolic syndromein adulhood,these SGA newborns will be have along‐term follow‐upfor examination of genetic and postnatal environmental factors.Gene expression of cord blood can be a usefuland noninvasive method of investigation of genetic alterationsin the fetal period. (Source: Pediatrics International)
Source: Pediatrics International - March 10, 2014 Category: Pediatrics Authors: Taketoshi Yoshida, Ichiro Takasaki, Hirokazu Kanegane, Satomi Inomata, Yasunori Ito, Kentaro Tamura, Masami Makimoto, Shigeru Saito, Yuko Yoshimoto, Toshio Miyawaki Tags: Original Article Source Type: research
Intra‐hospital Mortality among Neonates Transported by Ambulance in Colombia
ConclusionsWeight <1500 g, renal failure, congenital defects (except congenital cardiopathies) and high TRIPs values were associated with a higher risk of intra‐hospital mortality. The findings suggest that improving transfer time and quality of care in ambulances would decrease mortality. (Source: Pediatrics International)
Source: Pediatrics International - March 10, 2014 Category: Pediatrics Authors: Jorge Alvarado‐Socarras, Anderson Bermon, Nancy Bernal, Néstor F. Naranjo‐Estupiñán, Alvaro J. Idrovo Tags: Original Article Source Type: research
N‐terminal pro‐brain natriuretic peptide in the assessment of respiratory distress in term neonates
ConclusionTerm neonates with RD have significantly higher NT‐proBNP than healthy neonates. A single measurement of NT‐proBNP level cannot be used as the sole biomarker for distinguishing between cardiac and pulmonary cause of RD in term neonates. (Source: Pediatrics International)
Source: Pediatrics International - March 10, 2014 Category: Pediatrics Authors: Gordana Markovic‐Sovtic, Jovan Kosutic, Borisav Jankovic, Dragana Bojanin, Aleksandar Sovtic, Zoran Radojicic, M. Zorica Rakonjac Tags: Original Article Source Type: research
Factors influencing timing of neonatal discharge in Japan: Retrospective study
ConclusionsJapanese parents prefer the convenience of weekends over old superstitions about using the lunar calendar to determine the discharge date. (Source: Pediatrics International)
Source: Pediatrics International - March 10, 2014 Category: Pediatrics Authors: Yasushi Ishida, Yuko Nagaoki, Machiko Nakagawa, Michio Hirata, Rinshu Shimabukuro, Isao Kusakawa, Ryota Hosoya, Tsuguya Fukui Tags: Original Article Source Type: research
Respiratory severity score on day of life 30 is predictive of mortality and the length of mechanical ventilation in premature infants with protracted ventilation
ConclusionRSS ≥ 6 on day of life 30 is associated with higher mortality and longer period of mechanical ventilation in premature infants requiring mechanical ventilation through 30 days of life. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - March 10, 2014 Category: Respiratory Medicine Authors: Manish B. Malkar, William P. Gardner, George T. Mandy, Michael R. Stenger, Leif D. Nelin, Edward G. Shepherd, Stephen E. Welty Tags: Original Article: Neonatal Lung Disease Source Type: research
Pulmonary hypertension in bronchopulmonary dysplasia
Pulmonary hypertension is common in bronchopulmonary dysplasia and is associated with increased mortality and morbidity. This pulmonary hypertension is due to abnormal microvascular development and pulmonary vascular remodeling resulting in reduced cross‐sectional area of pulmonary vasculature. The epidemiology, etiology, clinical features, diagnosis, suggested management, and outcomes of pulmonary hypertension in the setting of bronchopulmonary dysplasia are reviewed. In summary, pulmonary hypertension is noted in a fifth of extremely low birth weight infants, primarily those with moderate or severe bronchopulmonary dys...
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - March 10, 2014 Category: Perinatology & Neonatology Authors: Namasivayam Ambalavanan, Peter Mourani Tags: Original Article Source Type: research
Polymorphisms of the gene encoding Kit ligand are associated with bronchopulmonary dysplasia
Conclusions: We show that KITLG polymorphisms are associated with susceptibility to moderate‐to‐severe BPD. In addition, higher Kit ligand concentrations were observed in infants that subsequently developed BPD. These results support the possibility that KITLG gene is involved in predisposition to BPD. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - March 9, 2014 Category: Respiratory Medicine Authors: Johanna M. Huusko, Mari Mahlman, Minna K. Karjalainen, Tuula Kaukola, Ritva Haataja, Riitta Marttila, Gergely Toldi, Miklós Szabó, Stephen F. Kingsmore, Mika Rämet, Pascal M. Lavoie, Mikko Hallman, Tags: Original Article: Neonatal Lung Disease Source Type: research
The Prevalence and Risk Factors of Paternal Depression from the Antenatal to the Postpartum Period and the Relationships between Antenatal and Postpartum Depression among Fathers in Hong Kong.
Conclusions. The present study points to the need for greater research and clinical attention to paternal depression given that it is a highly prevalent problem and could be detrimental to their spouse and children development. The present findings contribute to theoretical basis of the prevalence and risk factors of paternal perinatal depression and have implications of the design of effective identification, prevention, and interventions of these clinical problems. PMID: 24600517 [PubMed] (Source: Depression Research and Treatment)
Source: Depression Research and Treatment - March 8, 2014 Category: Psychiatry Tags: Depress Res Treat Source Type: research
At the Edges of Embodiment: Determinants of Breastfeeding for First Nations Women
Breastfeeding Medicine , Vol. 0, No. 0. (Source: Breastfeeding Medicine)
Source: Breastfeeding Medicine - March 8, 2014 Category: Perinatology & Neonatology Tags: article Source Type: research
Pregnancy complications in HIV‐positive women: 11‐year data from the Frankfurt HIV Cohort
ConclusionsIn the 11 years of our analysis, there was a significant reduction in the rate of preterm deliveries and an increase in the vaginal delivery rate, possibly reflecting changes in treatment policies in the same period and the availability of more effective antiretroviral therapy options. The rates of complications such as GDM, pre‐eclampsia, preterm contractions, PROM and postnatal complications were stable over the 11 years, but were still increased compared with the general population. (Source: HIV Medicine)
Source: HIV Medicine - March 7, 2014 Category: Infectious Diseases Authors: A Reitter, AU Stücker, R Linde, C Königs, G Knecht, E Herrmann, R Schlößer, F Louwen, A Haberl Tags: Original Research Source Type: research
Dangerous Combo: Violence in Pregnancy and HIV in South Africa
By Alisa HatfieldJOHANNESBURG, Mar 7 2014 (IPS) When Phumzile Khoza* came to the central Johannesburg antenatal clinic on a chilly day in August 2013, she was feeling on edge. Not about the medical procedures – she already had two children – but about talking to the nurse. One in four South African women experience intimate partner violence during pregnancy. Credit: Alisa Hatfield This was her third pregnancy living with HIV, but the first with a new partner from whom she had been hiding her status for the past two years. This pregnancy had been rocky from the start. Khoza had been trying to convince her partner to joi...
Source: IPS Inter Press Service - Health - March 7, 2014 Category: Global & Universal Authors: Alisa Hatfield Tags: Africa Countdown to ZERO Crime & Justice Featured Gender Gender Violence Headlines Health Population Poverty & MDGs Women's Health Domestic Violence HIV/AIDS Pregnancy South Africa Source Type: news
A Second Infant Reportedly Cleared of HIV After Early Therapy (FREE)
By Joe Elia A California baby is apparently the second case of an infant infected perinatally with HIV and showing no signs of infection after beginning early antiretroviral therapy. Details have been presented at the Conference … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 7, 2014 Category: Primary Care Source Type: news
Impact of environmental noise on growth and neuropsychological development of newborn rats
In conclusion, our results demonstrated that high noise exposure could decrease the production of growth hormone and SYP in neonatal rats, which may retard the growth of weight and length and the capability of learning and memory. Anat Rec, 2014. © 2014 Wiley Periodicals, Inc. (Source: The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology)
Source: The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology - March 7, 2014 Category: Molecular Biology Authors: Yanyan Zheng, Meng Meng, Congmin Zhao, Wei Liao, Yuping Zhang, Liyan Wang, Enyi Wen Tags: Full Length Article Source Type: research
Prenatal evaluation of the conus medullaris position in normal fetuses and fetuses with spina bifida occulta using three‐dimensional ultrasonography
Conclusions3D ultrasonography may accurately determine the CM vertebral level. Prenatal evaluation of the CM position may improve the detection and diagnosis of SBO. This article is protected by copyright. All rights reserved. (Source: Prenatal Diagnosis)
Source: Prenatal Diagnosis - March 7, 2014 Category: Perinatology & Neonatology Authors: Ting Lei, Hong‐Ning Xie, Ju Zheng, Jie‐Ling Feng, Liu Du, Nan Wang Tags: Original Article Source Type: research
Prenatal examination and postmortem findings in fetuses with gastroschisis and omphalocele
ConclusionThis study shows that the correlation between prenatal ultrasound findings and postmortem examination is good and has improved over time. Comparing full agreement during the first 10 years with the last 15 years showed an improvement (p = 0.05) for fetuses with omphalocele. This article is protected by copyright. All rights reserved. (Source: Prenatal Diagnosis)
Source: Prenatal Diagnosis - March 7, 2014 Category: Perinatology & Neonatology Authors: Tone Mæland Faugstad, Anne Brantberg, Harm‐Gerd K. Blaas, Christina Vogt Tags: Original Article Source Type: research
Innate defense regulator peptide 1018 protects against perinatal brain injury
ObjectiveThere is currently no pharmacological treatment that provides protection against brain injury in neonates. It is known that activation of an innate immune response is a key, contributing factor in perinatal brain injury; therefore, the neuroprotective therapeutic potential of innate defense regulator peptides (IDRs) was investigated. MethodsThe anti‐inflammatory effects of 3 IDRs was measured in lipopolysaccharide (LPS)‐activated murine microglia. IDRs were then assessed for their ability to confer neuroprotection in vivo when given 3 hours after neonatal brain injury in a clinically relevant model that combin...
Source: Annals of Neurology - March 7, 2014 Category: Neurology Authors: Hayde Bolouri, Karin Sävman, Wei Wang, Anitha Thomas, Norbert Maurer, Edie Dullaghan, Christopher D. Fjell, C. Joakim Ek, Henrik Hagberg, Robert E. W. Hancock, Kelly L. Brown, Carina Mallard Tags: Research Article Source Type: research
Is essential newborn care provided by institutions and after home births? Analysis of prospective data from community trials in rural South Asia
Conclusions: There remains substantial scope for health facilities to improve thermal care for the newborn and to encourage immediate and exclusive breastfeeding. For unattended home deliveries, increased handwashing, use of clean delivery kits and basic thermal care offer great scope for improvement. (Source: BMC Pregnancy and Childbirth - Latest articles)
Source: BMC Pregnancy and Childbirth - Latest articles - March 7, 2014 Category: OBGYN Authors: Christina PagelAudrey ProstMunir HossenKishwar AzadAbdul KuddusSwati RoyNirmala NairPrasanta TripathyNaomi SavilleAman SenCatherine SikorskiDharma ManandharAnthony CostelloSonya Crowe Source Type: research
Methicillin-Resistant Staphylococcus aureus Transmission and Infections in a Neonatal Intensive Care Unit despite Active Surveillance Cultures and Decolonization: Challenges for Infection Prevention
Victor O. Popoola, MBBS, MPH, ScM; Alicia Budd, MPH; Sara M. Wittig, MPH; Tracy Ross, BS; Susan W. Aucott, MD; Trish M. Perl, MD, MSc; Karen C. Carroll, MD; Aaron M. Milstone, MD, MHS Infection Control and Hospital Epidemiology, Volume 35, Issue 4, Page 412-418, April 2014. (Source: Infect Control Hosp Epidemiol Latest Issue)
Source: Infect Control Hosp Epidemiol Latest Issue - March 6, 2014 Category: Epidemiology Tags: article Original Articles Source Type: research
Another Class I recall for GE Healthcare
The FDA warns on new issues with GE Healthcare's neonatal warmers and resuscitation systems, which were recalled in October 2013. Federal healthcare regulators put their highest-risk Class I label on a new warning issued over GE Healthcare's (NYSE:GE) Giraffe and Panda neonatal infant warmers and resuscitation systems. Food & Drug Administration (FDA), GE HealthcareNews Well, Food & Drug Administration (FDA), Pediatrics, Recalls, Respiratory, Resuscitationread more (Source: Mass Device)
Source: Mass Device - March 6, 2014 Category: Medical Equipment Authors: Arezu Sarvestani Source Type: news
Angola: Malaria Remains Public Health Concern
[ANGOP]Malaria still remains a major public health concern in the country and particularly in its capital, Luanda, as the disease claims 40 percent of perinatal deaths and 25% of maternal mortality per year, said Wednesday the provincial director of Health, Rosa Bessa. (Source: AllAfrica News: Malaria)
Source: AllAfrica News: Malaria - March 6, 2014 Category: Infectious Diseases Source Type: news
Premature babies 'disadvantaged'
Research suggests that premature babies may be disadvantaged later in life by a dated educational system which doesn't accommodate them. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - March 6, 2014 Category: Consumer Health News Source Type: news
Is age at initiation of extracorporeal life support associated with mortality and intraventricular hemorrhage in neonates with respiratory failure?
Is age at initiation of extracorporeal life support associated with mortality and intraventricular hemorrhage in neonates with respiratory failure? Journal of Perinatology advance online publication, March 6 2014. doi:10.1038/jp.2013.156 Authors: K M Smith, D M McMullan, S L Bratton, P Rycus, J P Kinsella & T V Brogan (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 6, 2014 Category: Perinatology & Neonatology Authors: K M SmithD M McMullanS L BrattonP RycusJ P KinsellaT V Brogan Tags: neonatal respiratory distress syndrome meconium aspiration syndrome nitric oxide central nervous system hemorrhage Source Type: research
Association of adverse perinatal outcomes with screening measures of obstructive sleep apnea
amp; K M Aagaard (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 6, 2014 Category: Perinatology & Neonatology Authors: K M AntonyA AgrawalM E ArndtA M MurphyP M AlapatK K GuntupalliK M Aagaard Tags: obesity obstructive sleep apnea preeclampsia sleep-disordered breathing Source Type: research
The Children’s Hospitals Neonatal Database: an overview of patient complexity, outcomes and variation in care
The Children’s Hospitals Neonatal Database: an overview of patient complexity, outcomes and variation in care Journal of Perinatology advance online publication, March 6 2014. doi:10.1038/jp.2014.26 Authors: K Murthy, F D Dykes, M A Padula, E K Pallotto, K M Reber, D J Durand, B L Short, J M Asselin, I Zaniletti & J R Evans (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 6, 2014 Category: Perinatology & Neonatology Authors: K MurthyF D DykesM A PadulaE K PallottoK M ReberD J DurandB L ShortJ M AsselinI ZanilettiJ R Evans Tags: neonatal intensive care unit (NICU) outcomes levels of neonatal care Children’s Hospitals Neonatal Consortium (CHNC) practice variation regional NICU Source Type: research
Maternal pre-gravid body mass index and obstetric outcomes in twin gestations
C Maxwell (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 6, 2014 Category: Perinatology & Neonatology Authors: S Al-ObaidlyJ ParrishK E MurphyC Maxwell Tags: body mass index twins gestational hypertension gestational diabetes (GDM) preterm delivery neonatal intensive care unit (NICU) Source Type: research
Attitudes towards non-invasive prenatal testing for aneuploidy among US adults of reproductive age
p; M K Cho (Source: Journal of Perinatology)
Source: Journal of Perinatology - March 6, 2014 Category: Perinatology & Neonatology Authors: M AllyseL C SayresT A GoodspeedM K Cho Tags: prenatal testing prenatal diagnosis ethics Source Type: research
The usefulness of volume NT software in measuring the fetal nasal bone at 11 to 13 + 6 weeks of gestation
ConclusionsA 3D ultrasound supported by the volume nuchal translucency software may provide reliable measurements of the fetal NB in the first trimester. © 2014 John Wiley & Sons, Ltd. (Source: Prenatal Diagnosis)
Source: Prenatal Diagnosis - March 6, 2014 Category: Perinatology & Neonatology Authors: Michela Nanni, Elisa Maroni, Maurizio Bevini, Gianpaolo Cucchi, Elettra Pignotti, Gianluigi Pilu, Nicola Rizzo, Tullio Ghi Tags: Original Article Source Type: research
Cutaneous Fungal Infection in a Neonatal Intensive Care Unit Patient: A Case Report and Literature Review
We present the case of a premature neonate twin with cutaneous fungal infection in a neonatal intensive care unit. Because there were doubts concerning the correspondence of the clinical features with the cultured species in the newborn, a literature review was performed searching for similar clinical cases. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - March 6, 2014 Category: Dermatology Authors: Vesta Kucinskiene, Auguste Sutkute, Skaidra Valiukeviciene Tags: Case Report Source Type: research
Analysis of nitric oxide synthase gene polymorphisms in neonatal respiratory distress syndrome among the Chinese Han population
Aim: To evaluate the association of NOS1 and NOS3 gene polymorphisms with the risk/severity of neonatal respiratory distress syndrome (RDS) among preterm infants. Methods: The patient group was 189 preterm infants diagnosed with RDS. The control group was 227 preterm neonates who did not develop RDS. NOS genotyping was performed using an improved multiplex ligation detection reaction (iMLDR) technique based on LDR. Results: It was found that genotype and allele frequencies of rs2682826 of the NOS1 gene and rs1799983 of the NOS3 gene were not significantly different between the RDS group and the control group. However, when...
Source: Italian Journal of Pediatrics - March 6, 2014 Category: Pediatrics Authors: Wei ShenJiang DuBin WangQiyi Zeng Source Type: research
Neonatal invasive fungal infection in England 2004–2010
This study aimed to describe the current epidemiology of invasive neonatal fungal infections in a UK neonatal infection surveillance network. From 2004 to 2010 prospective multicentre surveillance was conducted by 14 neonatal units using a web‐based database. Clinicians then completed a standardized pro forma for each positive fungal blood and/or cerebrospinal fluid culture. The overall incidence was 2.4/1000 neonatal unit admissions and was highest among babies <1000 g (extreme low birthweight, 18.8/1000). Only five infants (6%) were >1500 g. The majority of infections were caused by Candida albicans (59; 69%) a...
Source: Clinical Microbiology and Infection - March 6, 2014 Category: Microbiology Authors: C. Oeser, S. Vergnano, R. Naidoo, M. Anthony, J. Chang, P. Chow, P. Clarke, N. Embleton, N. Kennea, S. Pattnayak, B. Reichert, T. Scorrer, I. Tiron, T. Watts, M. Sharland, P. T. Heath, Tags: Original Article Source Type: research
New England Journal of Medicine, Volume 370, Issue 10, Page 958, March 2014. (Source: New England Journal of Medicine)
Source: New England Journal of Medicine - March 5, 2014 Category: Internal Medicine Tags: article Source Type: research
Is the Presence of a Support Person During Prenatal Ultrasound Visits Associated With Improved Pregnancy Outcomes in Adolescents and Young Adults?
The objective of this study was to determine whether the presence of support person(s) at prenatal ultrasound visits of pregnant adolescents and young adults (AYA) is a marker for improved pregnancy outcomes and if the type of relationship has an effect on outcome. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - March 5, 2014 Category: OBGYN Authors: Margaret Kuper-Sassé, Sara Lee, Rina Lazebnik, Sara Bohac, Noam Lazebnik Tags: Poster Abstracts Source Type: research
Prevalence of Group B Beta Hemolytic Streptococcus in Teenagers
Group B Beta hemolytic streptococcus (GBBS) is a Gram positive bacteria known to cause significant morbidity and mortality in newborns. In 2010, there were more than 1,200 cases of neonatal sepsis with 30% mortality in infants delivered prior to 33 weeks gestation. Risk factors for early onset GBBS neonatal sepsis include teenage pregnancy and low maternal levels of GBS specific anticapsular antibody. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - March 5, 2014 Category: OBGYN Authors: Rachael L. Polis, Mark G. Martens, Jacqueline E. Feinberg, Jonathan D. Baum, Albert Rojtman Tags: Poster Abstracts Source Type: research
Serum and Urinary NGAL in Septic Newborns.
Abstract Neutrophil gelatinase-associated lipocalin (NGAL) is postulated to be a potentially new and highly specific/sensitive marker of acute kidney injury (AKI). The aim of this study was to assess the impact of inflammation on serum and urine NGAL in newborns that were treated due to infection. We determined serum and urine NGAL concentrations in 73 infants (51 with sepsis; 22 with severe sepsis) admitted to the Intensive Care Unit in the first month of life, for three consecutive days during the course of treatment for infection. 29 neonates without infection served as the control group. Septic patients, in par...
Source: Biomed Res - March 5, 2014 Category: Research Authors: Smertka M, Wroblewska J, Suchojad A, Majcherczyk M, Jadamus-Niebroj D, Owsianka-Podlesny T, Brzozowska A, Maruniak-Chudek I Tags: Biomed Res Int Source Type: research
Partial Correction of the CNS Lysosomal Storage Defect in a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis by Neonatal CNS Administration of an AAV Serotype rh.10 Vector Expressing the Human CLN3 Gene
Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)
Source: Human Gene Therapy - March 5, 2014 Category: Genetics & Stem Cells Tags: article Source Type: research
Gentamicin, genetic variation and deafness in preterm children
DiscussionIf there is an increased burden of hearing loss with m.1555A > G and aminoglycoside use, consideration will be given to genetic testing during pregnancy, postnatal testing prior to drug administration, or the use of an alternative first line antibiotic. Detailed perinatal data collection will also allow greater definition of the causal pathway of acquired hearing loss in very preterm children. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - March 5, 2014 Category: Epidemiology Authors: Maria Bitner-GlindziczShamima RahmanKathy ChantNeil Marlow Source Type: research
Balanced Diet During Pregnancy May Lower Risk of Preterm Delivery
Increasing intake of healthy foods more important than eliminating unhealthy foods, study finds Source: HealthDay Related MedlinePlus Pages: Pregnancy and Nutrition, Premature Babies (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 5, 2014 Category: Consumer Health News Source Type: news
A Knock‐in Foxj1CreERT2::GFP mouse for recombination in epithelial cells with motile cilia
Summary The transcription factor Foxj1 is expressed by cells destined to differentiate into epithelial cells projecting motile cilia into fluid‐ or air‐filled cavities. Here, we report the generation of an inducible knock‐in Foxj1CreERT2::GFP mouse, which we show reliably induces Cre‐mediated recombination for genetic studies in epithelial cells with motile cilia throughout embryonic and postnatal development. Induction during embryonic stages revealed efficient recombination in the epithelial component of the choroid plexus in the developing brain as early as E12.5. Induction during late embryonic stages showed co...
Source: genesis - March 5, 2014 Category: Genetics & Stem Cells Authors: Nagendran Muthusamy, Akshitha Vijayakumar, Gang Cheng, H. Troy Ghashghaei Tags: Technology Report Source Type: research
Tuberous sclerosis underlying neonatal poliosis
(Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - March 5, 2014 Category: Dermatology Authors: C. Schepis, M. Siragusa, A. Puzzo, C. Amato, M. Elia Tags: Letter to the Editor Source Type: research
Psychosocial Factors Are an Important Aspect of Parent and Patient-Reported Outcomes in Neonatal Brachial Plexus Palsy: Commentary on an article by Emily A. Eismann, MS, et al.: "The Relationship Between Medical Malpractice Litigation and Parent Reports of Patient Function Following Neonatal Brachial Plexus Palsy".
PMID: 24599215 [PubMed - in process] (Source: The Journal of Bone and Joint Surgery. American volume)
Source: The Journal of Bone and Joint Surgery. American volume - March 5, 2014 Category: Orthopaedics Authors: Abzug JM Tags: J Bone Joint Surg Am Source Type: research
The relationship between medical malpractice litigation and parent reports of patient function following neonatal brachial plexus palsy.
CONCLUSIONS: Litigation is associated with worse parent reports of children's function and pain following neonatal brachial plexus palsy, independent of age, injury severity, and the patients' own report of their function. Litigation status should be considered a confounding variable in the use of parent-reported outcomes in neonatal brachial plexus palsy research. Parents involved in litigation may benefit from additional support. PMID: 24599198 [PubMed - in process] (Source: The Journal of Bone and Joint Surgery. American volume)
Source: The Journal of Bone and Joint Surgery. American volume - March 5, 2014 Category: Orthopaedics Authors: Eismann EA, Bauer A, Kozin SH, Louden E, Cornwall R Tags: J Bone Joint Surg Am Source Type: research
Out-of-Hospital Births Up, but Key Data Missing
(MedPage Today) -- A federal government report suggested that out-of-hospital births are increasing, but the report omitted key information about attendants at home births and neonatal outcomes, according to one expert. (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - March 4, 2014 Category: OBGYN Source Type: news
Indicators of surgical treatment of patent ductus arteriosus in preterm neonates in the first week of life
CONCLUSION: The parameters DAD²/birth weight index > 5 mm²/kg, LA:Ao ratio > 1.5 and high ductal shunting were statistically significant indicators (P
Source: Revista Brasileira de Cirurgia Cardiovascular - March 4, 2014 Category: Cardiovascular & Thoracic Surgery Source Type: research
Tocolytics for preterm premature rupture of membranes.
CONCLUSIONS: Our review suggests there is insufficient evidence to support tocolytic therapy for women with PPROM, as there was an increase in maternal chorioamnionitis without significant benefits to the infant. However, studies did not consistently administer latency antibiotics and corticosteroids, both of which are now considered standard of care. PMID: 24578236 [PubMed - in process] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - March 4, 2014 Category: Journals (General) Authors: Mackeen AD, Seibel-Seamon J, Muhammad J, Baxter JK, Berghella V Tags: Cochrane Database Syst Rev Source Type: research
Probiotics for preventing gestational diabetes.
CONCLUSIONS: One trial has shown a reduction in the rate of GDM when women are randomised to probiotics early in pregnancy but more uncertain evidence of any effect on miscarriage/IUFD/stillbirth/neonatal death. There are no data on macrosomia. At this time, there are insufficient studies to perform a quantitative meta-analysis. Further results are awaited from four ongoing studies. PMID: 24574258 [PubMed - in process] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - March 4, 2014 Category: Journals (General) Authors: Barrett HL, Dekker Nitert M, Conwell LS, Callaway LK Tags: Cochrane Database Syst Rev Source Type: research