Perinatology & Neonatology Top 20This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

The Use of Sildenafil in Persistent Pulmonary Hypertension of the NewbornEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Amer J PerinatolDOI: 10.1055/s-0029-1239496ABSTRACTWe evaluated the effectiveness of sildenafil in the treatment of neonatal pulmonary hypertension. We performed a double-blind randomized clinical trial in 51 full-term infants with persistent pulmonary hypertension confirmed by Doppler echocardiography. Patients were divided in two groups: 20 infants in group A received placebo when the oxygenation index was >20, and 31 infants in group B received 3 mg/kg of oral sildenafil every 6 hours. Arterial blood gases were taken at 1, 4, 7, 13, 19, and 25 hours after treatment was started. Main outcome measures were oxygenation ...
Source: American Journal of Perinatology - October 29, 2009 Category: Perinatology & Neonatology Source Type: journals

Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The CNS-active VPA analogs containing a urea moiety, which have better anticonvulsant potency and lack teratogenicity, are good potential candidates as second-generation VPA antiepileptic drugs. Birth Defects Res (Part B) xx:1-8, 2009. © 2009 Wiley-Liss, Inc. (Source: Birth Defects Research Part B: Developmental and Reproductive Toxicology)
Source: Birth Defects Research Part B: Developmental and Reproductive Toxicology - October 14, 2009 Category: Perinatology & Neonatology Authors: Akinobu Okada, Hiroko Noyori, Boris Yagen, Jakob Avi Shimshoni, Meir Bialer, Michio Fujiwara Source Type: journals

Perinatal Neurofibromatosis: Two Case Reports and Review of the LiteratureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Amer J PerinatolDOI: 10.1055/s-0029-1241737ABSTRACTNeurofibromatosis-1 (NF-1) is an autosomal-dominant genetic disorder with many different manifestations. Some may have evidence of the disease at birth. A 66-year (1942 to 2008) retrospective review of 36 patients including 7 fetuses and 29 neonates with NF-1 was performed. Only patients with NF-1 lesions detected before birth by imaging or noted in the first month of life were entered into the review. There was a strongly positive family history of the disease of 70%. The most common presenting findings in the fetus were hydrops, macrocephaly, and thickened neck soft tiss...
Source: American Journal of Perinatology - October 29, 2009 Category: Perinatology & Neonatology Source Type: journals

Transport of the Neonatal Patient With Persistent Pulmonary HypertensionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article will review the pathophysiology, assessment, diagnosis, and treatment options for a newborn with persistent pulmonary hypertension of the newborn, and considerations for infant transport to a higher level of care will be emphasized. (Source: Newborn and Infant Nursing Reviews)
Source: Newborn and Infant Nursing Reviews - November 16, 2009 Category: Perinatology & Neonatology Authors: Peter Brust, Marjorie Hamburger, Patricia Larkin Tags: Articles Source Type: journals

Placental growth hormone and growth hormone binding protein are first trimester maternal serum markers of Down syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Placental growth hormone (PGH) is synthesised by the placenta, and its function is modulated by growth hormone binding protein (GHBP). The potential of PGH and GHBP as maternal serum screening markers for Down syndrome (DS) was examined.Maternal serum concentrations of PGH and GHBP were determined by ELISA in 74 DS and 261 control pregnancies in gestational week 8+0 to 13+4. Log10 MoM distributions of the markers were established. The performance of DS screening was estimated by Monte Carlo simulation.PGH log10 MoM (SD) was decreased (p < 0.001) to -0.201 (0.373) and GHBP log10 MoM to -0.116 (0.265) (p = 0.04), in DS pregn...
Source: Prenatal Diagnosis - October 20, 2009 Category: Perinatology & Neonatology Authors: Michael Christiansen Source Type: journals

Limb splinting for intravenous cannulae in neonates: a randomised controlled trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Joint immobilisation with splint at cannula site did not improve the functional duration of peripheral IV cannula. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - October 21, 2009 Category: Perinatology & Neonatology Authors: Dalal, S S, Chawla, D, Singh, J, Agarwal, R K, Deorari, A K, Paul, V K Tags: Clinical trials (epidemiology), Editor's choice, Immunology (including allergy), Child health, Neonatal and paediatric intensive care, Neonatal health, Radiology, Clinical diagnostic tests Original articles Source Type: journals

Gastroschisis: sonographic diagnosis, associations, management and outcomeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Gastroschisis is a defect in the abdominal wall, typically on the right side of a normally inserted umbilical cord through which bowel and other abdominal contents herniate. Classically, no membrane covers the herniated abdominal contents, which distinguishes the defect from exomphalos, an important differential diagnosis. Gastroschisis is usually diagnosed prenatally using ultrasound examination. The prevalence is increasing worldwide from approximately 0.1 per 10 000 total births in the 1970s to over 5 in the early 2000s. The reasons for this are unknown, but factors such as maternal smoking, recreational drugs and young...
Source: Prenatal Diagnosis - June 13, 2008 Category: Perinatology & Neonatology Authors: Anna L. David, Aileen Tan, Joseph Curry Source Type: journals

The effect of maternal obesity on the course of laborEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Maternal obesity is associated with active phase labor dysfunction, specifically arrest of dilatation. (Source: Journal of Perinatal Medicine)
Source: Journal of Perinatal Medicine - November 13, 2009 Category: Perinatology & Neonatology Source Type: journals

Parallel session 15: Fetal and neonatal neurodevelopmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Perinatal Medicine 37 (s1): 98-103 (Source: Journal of Perinatal Medicine)
Source: Journal of Perinatal Medicine - October 22, 2009 Category: Perinatology & Neonatology Source Type: journals

Prenatal factors in the development of chronic lung diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary: Chronic lung disease (CLD), defined as chronic oxygen dependency, is a common outcome of neonatal intensive care. It occurs most frequently in infants born very prematurely, but also in infants born at term who had severe lung disease and those with abnormal antenatal lung growth due particularly to reduction in fetal breathing movements, amniotic fluid volume or intrathoracic space. There are, however, other causes and the importance of antenatal infection/inflammation regarding impairment of antenatal lung growth is increasingly recognised. Affected infants can suffer chronic respiratory morbidity including an e...
Source: Seminars in Fetal and Neonatal Medicine - September 7, 2009 Category: Perinatology & Neonatology Authors: Anne Greenough Source Type: journals

Diagnosis and treatment of maternal acute myeloid leukemia during pregnancy imitating HELLP syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Perinatal Medicine 37 (6): 713-714 No abstract available (Source: Journal of Perinatal Medicine)
Source: Journal of Perinatal Medicine - November 13, 2009 Category: Perinatology & Neonatology Source Type: journals

Placental protein 13 as a first trimester screening marker for aneuploidyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To determine whether Placental Protein 13 (PP13) could be an additional marker in first trimester screening for aneuploidies.To evaluate differences in multiples of the gestation-specific normal median (MoMs), PP13 concentrations were measured in serum samples from Down syndrome, trisomy 18 and 13 affected pregnancies and euploid singleton pregnancies (four for each case matched for duration of storage, maternal weight and age).The PP13 MoM in Down syndrome cases (n = 153) was 0.91 [not statistically significant from controls (n = 853); P = 0.06; Wilcoxon rank sum test, two-tail]. PP13 MoMs were decreased in trisomy 18 (n ...
Source: Prenatal Diagnosis - October 19, 2009 Category: Perinatology & Neonatology Authors: M. P. H. Koster, E. J. Wortelboer, H. S. Cuckle, Ph. Stoutenbeek, G. H. A. Visser, P. C. J. I. Schielen Source Type: journals

Chorioamnionitis and Intrauterine Fetal Death after Second-Trimester AmniocentesisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Fetal Diagn Ther (DOI:10.1159/000257087) (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 4, 2009 Category: Perinatology & Neonatology Source Type: journals

Drug therapies in bronchopulmonary dysplasia: debunking the mythsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary: Bronchopulmonary dysplasia (BPD), also known as chronic lung disease (CLD), is one of the most challenging complications in premature infants. The incidence of BPD has been increasing over the past two decades in parallel with an improvement in the survival of this population. Furthermore, the clinical characteristics and the natural history of infants affected by BPD have changed considerably, and newer definitions to clarify the term ‘BPD’ have also evolved since its first description more than four decades ago. Several drug therapies have also evolved, either to manage these infants' respiratory distress sy...
Source: Seminars in Fetal and Neonatal Medicine - September 11, 2009 Category: Perinatology & Neonatology Authors: Win Tin, Thomas E. Wiswell Source Type: journals

Prologue: Advances in Bronchopulmonary DysplasiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
It has been 42 years since our first published report of bronchopulmonary dysplasia (BPD); it is still a problem for premature infants. The original goal of using mechanical ventilation to treat premature infants with respiratory distress syndrome and respiratory failure was to decrease the significant mortality. During the ensuing decades, a decrease in mortality has indeed occurred. Once recognized, it was hoped that a reduction of supplemental oxygen concentrations and ventilatory pressure would eliminate or decrease the incidence of BPD. This has, for the most part, been achieved in the 33 week gestational age infants ...
Source: Seminars in Fetal and Neonatal Medicine - September 25, 2009 Category: Perinatology & Neonatology Authors: William H. Northway Source Type: journals

Epidemiology of bronchopulmonary dysplasiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary: First described more than 40 years ago, bronchopulmonary dysplasia (BPD) remains one of the most serious and vexing challenges in the care of very preterm infants. Affecting approximately one-quarter of infants born (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - September 28, 2009 Category: Perinatology & Neonatology Authors: Linda J. Van Marter Source Type: journals

Symposium 2: Diabetes in pregnancyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Perinatal Medicine 37 (s1): 3-5 (Source: Journal of Perinatal Medicine)
Source: Journal of Perinatal Medicine - October 22, 2009 Category: Perinatology & Neonatology Source Type: journals

Parallel session 31: Obesity and perinatal outcomeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Perinatal Medicine 37 (s1): 165-167 (Source: Journal of Perinatal Medicine)
Source: Journal of Perinatal Medicine - October 22, 2009 Category: Perinatology & Neonatology Source Type: journals

Parallel session 11: Thrombophilia and pregnancyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Perinatal Medicine 37 (s1): 87-89 (Source: Journal of Perinatal Medicine)
Source: Journal of Perinatal Medicine - October 22, 2009 Category: Perinatology & Neonatology Source Type: journals

AmniSure International, LLCEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Perinatal Medicine 37 (s1): 956-956 (Source: Journal of Perinatal Medicine)
Source: Journal of Perinatal Medicine - October 22, 2009 Category: Perinatology & Neonatology Source Type: journals