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This page shows you the most recent publications within this specialty of the MedWorm directory.

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Vivus promotes COO to presidentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Vivus Inc. promoted Peter Tam, its chief operating officer, to president. (XOMA) (VVUS) (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - November 3, 2009 Category: Pharmaceuticals Source Type: journals

Advanced Medical Isotope Corporation Receives Positive Results from Initial Tests of a Proprietary and Innovative Method for the Domestic Production of Molybdenum-99Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
KENNEWICK, Wash., Nov. 3, 2009 (GLOBE NEWSWIRE) -- Advanced Medical Isotope Corporation ("AMIC") (Pinks Sheets:ADMD) (www.isotopeworld.com), a company engaged in the production and distribution of medical isotopes, is delighted to announce the encouraging results from initial tests conducted at Idaho State University (Pocatello, Idaho) in conjunction with researchers from the University of Missouri (Columbia, Missouri). (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - November 3, 2009 Category: Pharmaceuticals Source Type: news

Rigel reports $26.7M loss in Q3Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the third quarter ended September, Rigel Pharmaceuticals Inc. lost $26.7 million, down from a loss of $37.7 million in the same quarter a year earlier. (RIGL) (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - November 3, 2009 Category: Pharmaceuticals Source Type: journals

NanoLogix Inc.: NanoLogix Files International Patent Applications, Reclaims 18 Existing Patents, Noted in Department of Defense Quarterly Publication and Provides Operations UpdateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
HUBBARD, OH (MARKET WIRE) NanoLogix, Inc. (PINKSHEETS: NNLX) announces that the company has recently filed BNP™ (BioNanoPore) national patent applications in China, Japan, India, Brazil, Russia and the EU. These applications were filed in order to obtain intellectual property protection for the company's technology in countries viewed as representing the largest potential international market for BNP rapid detection, a revolutionary sandwiched-membrane Petri-based technology that can reduce microorganism detection times by 100-400%. (Source: Market Wire - Pharmaceuticals and Biotech)
Source: Market Wire - Pharmaceuticals and Biotech - November 3, 2009 Category: Pharmaceuticals Tags: Pharmaceuticals and Biotech Medical and Healthcare NNLX Source Type: news

Brookdale curbs losses in 3QEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Brookdale Senior Living Inc. reported a loss in the third quarter, but still showed improvement over the same period last year. (BKD) (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - November 3, 2009 Category: Pharmaceuticals Source Type: journals

N.C. workers’ comp premiums to drop 9.6%Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Businesses in North Carolina will pay less for workers’ compensation insurance next year, according to the N.C. Department of Insurance. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - November 3, 2009 Category: Pharmaceuticals Source Type: journals

Ambrilia Biopharma Inc.: Ambrilia Biopharma Provides Bi-Weekly Status UpdateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
MONTREAL, QUEBEC (MARKET WIRE) Ambrilia Biopharma Inc. (TSX: AMB) is providing today its bi-weekly Default Status Report under National Policy 12-203 - Cease Trade Orders for Continuous Disclosure Defaults ("Default Status Report"). (Source: Market Wire - Pharmaceuticals and Biotech)
Source: Market Wire - Pharmaceuticals and Biotech - November 3, 2009 Category: Pharmaceuticals Tags: Pharmaceuticals and Biotech AMB Source Type: news

Cutting Edge Information: Pharmaceutical Speaker Programs an Important Source of Medical Education, Says Cutting Edge InformationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
RESEARCH TRIANGLE PARK, NC (MARKET WIRE) Like many other marketing activities within the industry, pharmaceutical speaker programs -- and the physician-industry relationships that they consist of -- are under attack, most recently by the Boston Globe. (Source: Market Wire - Pharmaceuticals and Biotech)
Source: Market Wire - Pharmaceuticals and Biotech - November 3, 2009 Category: Pharmaceuticals Tags: Pharmaceuticals and Biotech Medical and Healthcare Source Type: news

J&J to Cut Up to 7% of Work ForceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Johnson & Johnson announced plans to lay off as many as 8,400 employees worldwide -- 7%of its work force -- as part of a move to save up to $1.7 billion in 2011. (Source: WSJ.com: Health)
Source: WSJ.com: Health - November 3, 2009 Category: Pharmaceuticals Tags: PAID Source Type: news

IPOdesktop.com Internet Radio Series Interviews Orthopedic Surgeon Dr. Eugene Wolf, Who Sees Multiple Applications in His Specialty for BioSpecifics' XIAFLEX(TM)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
LYNBROOK, N.Y., Nov. 3, 2009 (GLOBE NEWSWIRE) -- IPOdesktop.com, in a continuation of its Internet radio interviews featuring BioSpecifics Technologies Corp. (Nasdaq:BSTC), today features an interview with Dr. Eugene Wolf. Dr. Wolf is based in San Francisco, and is a board certified orthopedic surgeon who has practiced in the Bay area for the past 30 years. In the interview, Dr. Wolf says that XIAFLEX may have broad applications within his area of specialization, particularly in frozen shoulder and knee surgery, where XIAFLEX has the potential to shorten the entire healing process. (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - November 3, 2009 Category: Pharmaceuticals Source Type: news

Quintiles Announces Clinical Pharmacology Alliance With AstraZenecaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Quintiles today announced that it has entered into in an industry-leading clinical pharmacology alliance with AstraZeneca to deliver AstraZeneca's clinical pharmacology studies across multiple therapy areas and around the globe. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - November 3, 2009 Category: Pharmaceuticals Source Type: news

Viking Systems, Inc. Reports Third Quarter Results; Provides Business UpdatesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
WESTBOROUGH, Mass., Nov. 3, 2009 (GLOBE NEWSWIRE) -- Viking Systems, Inc. (OTCBB:VKNG), a supplier of 2D and 3D visualization systems for the medical market, today announced results for the quarter ended September 30, 2009. The Company reported that it has made significant progress in its objective to reach sustainable positive cash flow from operations and that it is exploring strategic and financing options in order to fund anticipated 2010 operating losses while the Company develops and launches its "Next Generation" 3DHD Visualization System. Additionally, the Company discussed a significant order for its current 3Di s...
Source: Medical News (via PRIMEZONE) - November 3, 2009 Category: Pharmaceuticals Source Type: news

K2M Enters Japanese Spine MarketEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
MESA Spinal System Clearance Enables Sale and Distribution in Japan LEESBURG, Va., Nov. 3--(HSMN NewsFeed)--K2M, Inc., the spinal device company developing innovative and simplified solutions for the treatment of complex spinal pathologies and procedure... Devices, Orthopaedic, NeurosurgeryK2M, MESA Spinal System, spine surgery (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 3, 2009 Category: Pharmaceuticals Source Type: news

LDR's VerteBRIDGE Plating Technology Reaches New MilestoneEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
AUSTIN, Texas, Nov 3--(HSMN NewsFeed)--LDR, a total spine solution company, announced today that since product launch 18 months ago there have been more than 3,000 devices with VerteBRIDGE plating technology implanted worldwide. Over 2,500 of these device... Devices, Orthopaedic, NeurosurgeryLDR Spine, VerteBRIDGE, ROI-A, ROI-C, spine surgery (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 3, 2009 Category: Pharmaceuticals Source Type: news

29.10.09: Bonds: EMTN ProgramEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bonds: EMTN ProgramNew: Supplement dated October 28, 2009 Link to websiteAll changes (Source: Bayer IR Newsfeed: New on this site)
Source: Bayer IR Newsfeed: New on this site - November 3, 2009 Category: Pharmaceuticals Source Type: news

ZEVALIN® Receives Positive Reimbursement Ruling Using Average Sales Price (ASP) MethodologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ZEVALIN Was Recently Approved by the FDA for the Treatment Of Patients With Previously Untreated Follicular Non-Hodgkins Lymphoma (NHL), Who Achieve A Partial Or Complete Response To First-Line Chemotherapy IRVINE, Calif., Nov 3--(HSMN NewsFeed)--Spect... Biopharmaceuticals, Oncology, ReimbursementSpectrum Pharmaceuticals, ZEVALIN, ibritumomab tiuxetan, non-Hodgkins Lymphoma (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 3, 2009 Category: Pharmaceuticals Source Type: news

VIVUS Announces Promotion of Peter Tam to PresidentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Tam Also Appointed to VIVUS Board of Directors MOUNTAIN VIEW, Calif., Nov. 3 (HSMN NewsFeed) -- VIVUS, Inc. (Nasdaq: VVUS ) today announced the promotion of Peter Tam to president of VIVUS. In this position, Mr. Tam will lead and have overall responsi... Biopharmaceuticals, PersonnelVIVUS (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 3, 2009 Category: Pharmaceuticals Source Type: news

Symphogen Opens US Operations in Princeton, New JerseyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
US Subsidiary Supports Expanding Opportunities for Symphogens Novel Antibody Pipeline and Discovery and Expression Platforms COPENHAGEN & PRINCETON, N.J., Nov 3--(HSMN NewsFeed)--Symphogen A/S today announced the opening of its United States headquarte... BiopharmaceuticalsSymphogen (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 3, 2009 Category: Pharmaceuticals Source Type: news

Johnson & Johnson Announces Restructuring Initiatives for Sustainable Growth (Nov 3, 2009)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New Brunswick, NJ (Nov. 3, 2009) – Johnson & Johnson today announced global restructuring initiatives designed to strengthen the company’s position as the world’s leading global health care company. The company is taking steps to prioritize its innovation efforts around the many growth opportunities in health care and to execute aggressively on bringing key new products to market. ..... (Source: Johnson and Johnson)
Source: Johnson and Johnson - November 3, 2009 Category: Pharmaceuticals Source Type: organizations

LHC Group and Twin Lakes Regional Medical Center Announce Home Health Joint VentureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
LAFAYETTE, La., Nov. 3, 2009 (GLOBE NEWSWIRE) -- LHC Group, Inc. (Nasdaq:LHCG), one of the largest providers of home health services in the United States, announced today that it has entered into a home health joint venture with Twin Lakes Regional Medical Center in Leitchfield, Kentucky. (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - November 3, 2009 Category: Pharmaceuticals Source Type: news

Trading Outlook for Illumina Inc. Issued by StockPreacher.comEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
DALLAS, Nov. 3, 2009 (GLOBE NEWSWIRE) -- StockPreacher.com announces an investment report featuring Illumina Inc. (Nasdaq:ILMN). The report includes financial, comparative and investment analyses, and pertinent industry information you need to know to make an educated investment decision. (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - November 3, 2009 Category: Pharmaceuticals Source Type: news

Heart Valve for Boy With Swine FluEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Doctors at Children's Hospital Boston successfully implanted an experimental heart valve in a boy with a congenital heart defect to relieve potentially fatal complications caused by swine flu. (Source: WSJ.com: Health)
Source: WSJ.com: Health - November 3, 2009 Category: Pharmaceuticals Tags: FREE Source Type: news

Matsyafed sniffs new biz in nutraceutical domainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Matsyafed has been engaged in the implementation of a broad range of welfare schemes for the fishing community, with the objective of ensuring their socio-economic uplift. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 3, 2009 Category: Pharmaceuticals Source Type: news

Accentia to tap European marketEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Healthcare receivables cycle management major Accentia Technologies based at the Technopark here has commenced operations from the UK, with the objective of tapping potential markets in Northern Ireland, England and Scotland (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 3, 2009 Category: Pharmaceuticals Source Type: news

Sikkim turns into a pharma hubEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sikkim, which is the least populous state in the country and the second-smallest after Goa, has already attracted pharma investment upwards of Rs 2,500 crore. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 3, 2009 Category: Pharmaceuticals Source Type: news

Twice Daily Oral Medication Shows Promise In Treating Patients With Hepatitis CEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
All approved therapy regimens to treat patients with hepatitis C are based on interferon, which must be injected. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - November 3, 2009 Category: Pharmaceuticals Source Type: news

ViiV Healthcare launches: A new specialist HIV company dedicated to delivering advances in HIV treatment and careEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dr Dominique Limet, CEO of ViiV Healthcare, promises 'relentless pursuit' of new treatments (Source: GSK news)
Source: GSK news - November 3, 2009 Category: Pharmaceuticals Source Type: organizations

Air Powered Industrial Vacuum Cleaner For Liquid RecoveryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The VAC-U-MAX Model TK-01 is a unique industrial vacuum cleaner designed for high-speed transfer of various liquids directly into a closed top 55-gallon drum. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - November 3, 2009 Category: Pharmaceuticals Source Type: news

New Twin Stick Dual Chamber Stick Pack DesignEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PTI Packaging Systems recently introduced new Twin Stick, the new innovative design for stick packaging that consists of a dual chamber stick pack to create product combinations such as sugar and spoon, salt and pepper, sugar and coffee creamer, shampoo and conditioner, etc. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - November 3, 2009 Category: Pharmaceuticals Source Type: news

Flash Points Linger in Health BillEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
House Democrats are wrestling with how their health-care bill will deal with abortion and immigration issues as they prepare to bring the bill to the floor. (Source: WSJ.com: Health)
Source: WSJ.com: Health - November 3, 2009 Category: Pharmaceuticals Tags: FREE Source Type: news

Home Flu Cures: Bad Medicine?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Amid the frenzy to fight swine flu, folk remedies such as keeping raw onion in the room or eating homemade chicken soup are gaining ground. Melinda Beck asks if any of them actually work. (Source: WSJ.com: Health)
Source: WSJ.com: Health - November 3, 2009 Category: Pharmaceuticals Tags: FREE Source Type: news

Heart Valve Implanted in Boy With Swine FluEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Doctors at Children's Hospital Boston successfully implanted an experimental heart valve in a boy with a congenital heart defect to relieve potentially fatal complications caused by swine flu. (Source: WSJ.com: Health)
Source: WSJ.com: Health - November 3, 2009 Category: Pharmaceuticals Tags: FREE Source Type: news

Is There a Case of the Flu in Your Future?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Imagine if a simple test could tell whether you were going to come down with the flu or a cold even before you get hit by a sore throat, runny nose or fever. Stay tuned, scientists say. (Source: WSJ.com: Health)
Source: WSJ.com: Health - November 3, 2009 Category: Pharmaceuticals Tags: FREE Source Type: news

Sanofi-aventis delivers a solid performance in third quarter 2009Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In the third quarter of 2009, sanofi-aventis generated net sales of €7,400 million, up 8.0% on a reported basis. Exchange rate movements had a favorable effect of 2.0 percentage points, with the appreciation of the U.S. dollar (and to a lesser extent the yen) against the euro more than offsetting the unfavorable effects of some other currencies. (Source: World Pharma News)
Source: World Pharma News - November 3, 2009 Category: Pharmaceuticals Source Type: news

An FDA Expert on Protecting Yourself Against the FDAEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cerulean's co-founder and managing director, John Avellanet, will reprise his talk from September this coming December in an encore presentation of 'Bulletproof Yourself against FDA Enforcement in 2010'. "I received at least half a dozen emails from folks who wanted to attend another live event," said Mr Avellanet. "This is probably the most popular webinar and teleconference I give – it fills up every single time." In ninety minutes Mr Avellanet covers the FDA's directions and priorities for the following year, how firms can identify and mitigate their specific challenges when it comes ... (Source: Drug Development Technology)
Source: Drug Development Technology - November 3, 2009 Category: Pharmaceuticals Source Type: info

Heart Valve Implanted in Boy With Swine FluEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Doctors at Children's Hospital Boston successfully implanted an experimental heart valve in a boy with a congenital heart defect to relieve potentially fatal complications caused by swine flu. (Source: WSJ.com: Health)
Source: WSJ.com: Health - November 2, 2009 Category: Pharmaceuticals Tags: FREE Source Type: news

Amylin Pharmaceuticals and Eli Lilly and Company Statement on FDA's Byetta (Exenatide) Injection UpdateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
SAN DIEGO and INDIANAPOLIS, Nov. 2, 2009 /PRNewswire-FirstCall/ -- Amylin Pharmaceuticals, Inc., (NASDAQ:AMLN) and Eli Lilly and Company (NYSE:LLY) today issued the following statement in response to the U.S. Food and Drug Administration (FDA)... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 2, 2009 Category: Pharmaceuticals Source Type: news

Mayo Clinic Proceedings Publishes Study of NUVIGIL in Patients with Shift Work DisorderEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
FRAZER, Pa., Nov. 2 /PRNewswire-FirstCall/ -- Cephalon, Inc. (Nasdaq: CEPH) today announced that the November issue of Mayo Clinic Proceedings has published data from a pivotal Phase III trial demonstrating that NUVIGIL® (armodafinil) Tablets... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - November 2, 2009 Category: Pharmaceuticals Source Type: clinical trials

Schering-Plough Reports Potent Antiviral Activity With Narlaprevir (SCH 900518), an Investigational, Once-Daily Protease Inhibitor for Hepatitis CEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Interim results of Phase IIa NEXT-I study presented at American Association for the Study of Liver Diseases (AASLD) Annual Meeting BOSTON, Nov. 2 /PRNewswire-FirstCall/ -- Schering-Plough Corporation (NYSE: SGP) today reported that interim results... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - November 2, 2009 Category: Pharmaceuticals Source Type: clinical trials

Byetta (exenatide) - Altered kidney function, including acute renal failure/renal insufficiency, in patients on ByettaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ROCKVILLE, Md., Nov. 2, 2009--FDA notified healthcare professionals of revisions to the prescribing information for Byetta (exenatide) to include information on post-marketing reports of altered kidney function, including acute renal failure... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 2, 2009 Category: Pharmaceuticals Source Type: news

Pacifiers Linked to Speech DisordersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New medical findings on children who use pacifiers for at least three years developing speech disorders, nicotine patches that promote the spread of cancer, and more. (Source: WSJ.com: Health)
Source: WSJ.com: Health - November 2, 2009 Category: Pharmaceuticals Tags: FREE Source Type: news

GOP Health Bill Gives Insurers LeewayEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
House Minority Leader John Boehner said a Republican health-care bill being released this week wouldn't seek to prevent health-insurance companies from denying sick people insurance. (Source: WSJ.com: Health)
Source: WSJ.com: Health - November 2, 2009 Category: Pharmaceuticals Tags: FREE Source Type: news

Competitive Technologies Booking Revenue From Worldwide Shipments of Pain Therapy Medical DevicesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
FAIRFIELD, Conn., Nov. 2, 2009 (GLOBE NEWSWIRE) -- Competitive Technologies, Inc. (NYSE Amex:CTT) announced today that it is moving forward with its plan to restore profitability. Its Calmare Therapy Treatment*, pain therapy medical device is treating patients in several locations worldwide. Revenue for product shipments has been recorded for shipments made during the fiscal quarter ended October 31, 2009. (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - November 2, 2009 Category: Pharmaceuticals Source Type: news

NovaBay's Aganocides Show Penetration and Efficacy in a Pre-Clinical Infected Human Nail Model of OnychomycosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Data to be presented at Infectious Diseases Society of America Conference EMERYVILLE, Calif., Oct. 30 /PRNewswire-FirstCall/ -- NovaBay Pharmaceuticals, Inc. (NYSE-Amex: NBY) today announced that its Aganocide® compounds demonstrate potent... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - November 2, 2009 Category: Pharmaceuticals Source Type: clinical trials