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This page shows you the most recent publications within this specialty of the MedWorm directory.

Electric shocks to brain help students solve maths problems, scientists say
Psychologists find students do puzzles 27% faster after non-invasive procedure than those who had no treatmentPeople who struggle with maths problems might fare better after a course of gentle electric shocks to the brain, scientists have claimed.Psychologists at Oxford University found that students scored higher on mental arithmetic tasks after a five-day course of brain stimulation.If future studies prove that it works – and is safe – the cheap and non-invasive procedure might be used routinely to boost the cognitive power of those who fall behind in maths, the scientists said. Researchers led by Roi Cohen Kadosh za...
Source: Guardian Unlimited Science - May 16, 2013 Category: Science Authors: Ian Sample Tags: University of Oxford Psychology News guardian.co.uk Mathematics Higher education UK news Science Source Type: news

Accelerometry-based gait analysis and its application to Parkinson's disease assessment. Part 1: Detection of stride event accelerometry-based gait analysis and its application to Parkinson's disease assessment. Part 2: a new measure for quantifying walking behavior - Yoneyama M, Mitoma H, Watanabe K, Kurihara Y.
Gait analysis is a valuable tool for obtaining quantitative information on motor deficits in Parkinson's disease (PD). Since the characteristic gait patterns of PD patients may not be fully identified by brief examination in a clinic, long-term and unobtru... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - May 16, 2013 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Aggressive behavior: A comprehensive review of its neurochemical mechanisms and management - Umukoro S, Aladeokin AC, Eduviere AT.
Aggression is a deliberate series of actions that lead to harm, injury, or destruction of another organism, and is the most common factor promoting violent crimes. Beyond being the immediate cause of physical injury, aggressive behavior also produces profo... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - May 16, 2013 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Brugada electrocardiographic pattern in carbon monoxide poisoning - Palaniswamy C, Aronow WS, Sugunaraj JP, Kang JJ, Kar K, Kalra A.
[Abstract unavailable] Language: Eng... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - May 16, 2013 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Effect of HFACS and non-HACFS-related factors on fatalities in general aviation accidents using neural networks - Liu D, Nickens T, Hardy L, Boquet A.
This study applied a backpropagation artificial neural network approach to investigate both the Human Factors Analysis and Classification System (HFACS)-related unsafe act tiers of factors and other non-HFACS factors in an attempt to recognize patterns for... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - May 16, 2013 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

When worlds collide--elite sport, doping, and scientific research
(Source: Journal of Applied Physiology)
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Wagner, P. D. Tags: EDITORIALS Source Type: research

Reconsideration of a Tour de France cyclist
(Source: Journal of Applied Physiology)
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Coyle, E. F. Tags: EDITORIALS Source Type: research

Ethical considerations for experiments involving elite athletes and "doping"
(Source: Journal of Applied Physiology)
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Schumacher, Y. O., Garvican, L. A., Pottgiesser, T., Martin, D. T., Ahlgrim, C., Gore, C. J. Tags: LETTERS TO THE EDITOR Source Type: research

Reply to Schumacher et al.
(Source: Journal of Applied Physiology)
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Lundby, C., Robach, P. Tags: LETTERS TO THE EDITOR Source Type: research

Scientific research using elite athletes: WADA point of view
(Source: Journal of Applied Physiology)
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Howman, D. Tags: LETTERS TO THE EDITOR Source Type: research

Phosphorylation of myocardial eNOS is altered in patients suffering from type 2 diabetes
The present study investigated whether endothelial nitric oxide synthase (eNOS) activation may be dysregulated in cardiac tissue of patients suffering from type 2 diabetes (T2D). We performed immunohistochemical measurements of translocated eNOS activation as well as eNOS phosphorylation at Ser1177, Thr495, Ser 635, Ser114, and of the protein kinase B (Akt) in isolated right atrial trabeculae of patients undergoing cardiac bypass or valve surgery with (n = 12, 68.1 ± 2.5 yr) and without T2D (n = 12, 64.7 ± 2.7 yr). In addition, we investigated oxidative (8-isoprostane) and nitrosative stress markers (nitrotyr...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Streit, U., Reuter, H., Bloch, W., Wahlers, T., Schwinger, R. H. G., Brixius, K. Tags: ARTICLES Source Type: research

Racial differences in the response of cardiorespiratory fitness to aerobic exercise training in Caucasian and African American postmenopausal women
African American (AA) women have an elevated risk of cardiovascular disease and have been reported to have lower cardiorespiratory fitness (CRF) compared with Caucasian American (CA) women. However, little data exist that evaluate racial differences in the change in CRF following aerobic exercise training. CA (n = 264) and AA (n = 122) postmenopausal women from the Dose-Response to Exercise in Women study were randomized to 4, 8, and 12 kcal·kg body wt–1·wk–13 (KKW) of aerobic training or the control group for 6 mo. CRF was evaluated using a cycle ergometer. A greater increase in relative CRF was ...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Swift, D. L., Johannsen, N. M., Lavie, C. J., Earnest, C. P., Johnson, W. D., Blair, S. N., Church, T. S., Newton, R. L. Tags: ARTICLES Source Type: research

Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults
Recently, several high-impact reviews suggest that regular aerobic exercise is beneficial for maintaining cognitive function in aging adults. Higher cerebral blood flow and/or cerebrovascular reactivity may explain the favorable effect of exercise on cognition. In addition, prostaglandin-mediated vasodilator responses may be influenced by regular exercise. Therefore, our purpose was to evaluate middle cerebral artery (MCA) vasodilator responses in healthy adults before and after cyclooxygenase inhibition. A total of 16 young (26 ± 6 yr; 8 males, 8 females) and 13 older (64 ± 6 yr; 7 males, 6 females) healthy ...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Barnes, J. N., Taylor, J. L., Kluck, B. N., Johnson, C. P., Joyner, M. J. Tags: ARTICLES Source Type: research

Inactivity-induced phrenic and hypoglossal motor facilitation are differentially expressed following intermittent vs. sustained neural apnea
Reduced respiratory neural activity elicits a rebound increase in phrenic and hypoglossal motor output known as inactivity-induced phrenic and hypoglossal motor facilitation (iPMF and iHMF, respectively). We hypothesized that, similar to other forms of respiratory plasticity, iPMF and iHMF are pattern sensitive. Central respiratory neural activity was reversibly reduced in ventilated rats by hyperventilating below the CO2 apneic threshold to create brief intermittent neural apneas (5, ~1.5 min each, separated by 5 min), a single brief massed neural apnea (7.5 min), or a single prolonged neural apnea (30 min). Upon restorat...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Baertsch, N. A., Baker-Herman, T. L. Tags: ARTICLES Source Type: research

Bubbles, microparticles, and neutrophil activation: changes with exercise level and breathing gas during open-water SCUBA diving
The study goal was to evaluate responses in humans following decompression from open-water SCUBA diving with the hypothesis that exertion underwater and use of a breathing mixture containing more oxygen and less nitrogen (enriched air nitrox) would alter annexin V-positive microparticle (MP) production and size changes and neutrophil activation, as well as their relationships to intravascular bubble formation. Twenty-four divers followed a uniform dive profile to 18 m of sea water breathing air or 22.5 m breathing 32% oxygen/68% nitrogen for 47 min, either swimming with moderately heavy exertion underwater or remaining sta...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Thom, S. R., Milovanova, T. N., Bogush, M., Yang, M., Bhopale, V. M., Pollock, N. W., Ljubkovic, M., Denoble, P., Madden, D., Lozo, M., Dujic, Z. Tags: ARTICLES Source Type: research

Active, passive, and motor imagery paradigms: component analysis to assess neurovascular coupling
The association between neural activity and cerebral blood flow (CBF) has been used to assess neurovascular coupling (NVC) in health and diseases states, but little attention has been given to the contribution of simultaneous changes in peripheral covariates. We used an innovative approach to assess the contributions of arterial blood pressure (BP), PaCO2, and the stimulus itself to changes in CBF velocities (CBFv) during active (MA), passive (MP), and motor imagery (MI) paradigms. Continuous recordings of CBFv, beat-to-beat BP, heart rate, and breath-by-breath end-tidal CO2 (EtCO2) were performed in 17 right-handed subjec...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Salinet, A. S. M., Robinson, T. G., Panerai, R. B. Tags: ARTICLES Source Type: research

Antibody and CD8+ T cell memory response to influenza A/PR/8/34 infection is reduced in treadmill-exercised mice, yet still protective
Moderate exercise may decrease the severity of influenza infection and reduce lung viral load. The possibility that an exercise-associated reduction in lung viral load early in infection could contribute to decreased serum antibody and reduced memory response were investigated. BALB/c mice exercised for 8 wk and were then infected with influenza A/PR/8/34 (intranasal route). Influenza-specific serum antibody was assessed for 6 mo post primary infection, at which time mice were infected again with influenza A/PR/8/34. After primary infection, exercise reduced morbidity/mortality, attenuated lung cytokines, and decreased ser...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Warren, K., Thompson, N., Wannemuehler, M., Kohut, M. Tags: ARTICLES Source Type: research

Local metabolic rate during whole body vibration
Whole body vibration (WBV) platforms are currently used for muscle training and rehabilitation. However, the effectiveness of WBV training remains elusive, since scientific studies vary largely in the vibration parameters used. The origin of this issue may be related to a lack in understanding of the training intensity that is imposed on individual muscles by WBV. Therefore, this study evaluates the training intensity in terms of metabolic rate of two lower-extremity muscles during WBV under different vibration parameters. Fourteen healthy male subjects were randomly exposed to 0 (control)-, 10-, 17-, and 28-Hz vibrations ...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Friesenbichler, B., Nigg, B. M., Dunn, J. F. Tags: ARTICLES Source Type: research

Comparison of neuromuscular adjustments associated with sustained isometric contractions of four different muscle groups
In conclusion, despite different times to task failure when sustaining an isometric contraction at 50% MVC force for as long as possible, diverse muscle groups present similar loss of MVC force after task failure. Thus the extent of muscle fatigue is not affected by time to task failure, whereas this latter determines the etiology of fatigue. (Source: Journal of Applied Physiology)
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Neyroud, D., Ruttimann, J., Mannion, A. F., Millet, G. Y., Maffiuletti, N. A., Kayser, B., Place, N. Tags: ARTICLES Source Type: research

Dihydrotestosterone is elevated following sprint exercise in healthy young men
In conclusion, our data demonstrate that DHT is acutely elevated following sprint cycle exercise and that this response is influenced by cycling cadence. The importance of DHT in the context of exercise training and sports performance remains to be determined. (Source: Journal of Applied Physiology)
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Smith, A. A., Toone, R., Peacock, O., Drawer, S., Stokes, K. A., Cook, C. J. Tags: ARTICLES Source Type: research

Altitude, pasture type, and sheep breed affect bone metabolism and serum 25-hydroxyvitamin D in grazing lambs
This study aimed to investigate the bone development of two mountain sheep breeds during natural summer grazing either in the lowlands or on different characteristic alpine pastures. Pasture types differed in topographic slope, plant species composition, general nutritional feeding value, Ca and P content, and Ca:P ratio of herbage. Twenty-seven Engadine sheep (ES) lambs and 27 Valaisian Black Nose sheep (VS) lambs were divided into four groups of 6 to 7 animals per breed and allocated to three contrasting alpine pasture types and one lowland pasture type. The lambs were slaughtered after 9 wk of experimental grazing. The ...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Willems, H., Leiber, F., Kohler, M., Kreuzer, M., Liesegang, A. Tags: ARTICLES Source Type: research

Two-layer model of coronary artery vasoactivity
Since vascular tone is regulated by smooth muscle cells in the media layer, a multilayer mechanical model is required for blood vessels. Here, we performed biaxial mechanical tests in the intima-media layer of right coronary artery to determine the passive and active properties in conjunction with the passive properties of adventitia for a full vessel wall model. A two-layer (intima-media and adventitia) model was developed to determine the transmural stress and stretch across the vessel wall. The mean ± SE values of the outer diameters of intima-media layers at transmural pressure of 60 mmHg in active state were 3....
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Huo, Y., Zhao, X., Cheng, Y., Lu, X., Kassab, G. S. Tags: ARTICLES Source Type: research

Airway narrowing and bronchodilation to deep inspiration in bronchial segments from subjects with and without reported asthma
The present study presents preliminary findings on how structural/functional abnormalities of the airway wall relate to excessive airway narrowing and reduced bronchodilatory response to deep inspiration (DI) in subjects with a history of asthma. Bronchial segments were acquired from subjects undergoing surgery, mostly to remove pulmonary neoplasms. Subjects reported prior doctor-diagnosed asthma (n = 5) or had no history of asthma (n = 8). In vitro airway narrowing in response to acetylcholine was assessed to determine maximal bronchoconstriction and sensitivity, under static conditions and during simulated tidal and DI m...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Noble, P. B., Jones, R. L., Cairncross, A., Elliot, J. G., Mitchell, H. W., James, A. L., McFawn, P. K. Tags: ARTICLES Source Type: research

Quantification of left and right atrial kinetic energy using four-dimensional intracardiac magnetic resonance imaging flow measurements
Kinetic energy (KE) of atrial blood has been postulated as a possible contributor to ventricular filling. Therefore, we aimed to quantify the left (LA) and right (RA) atrial blood KE using cardiac magnetic resonance (CMR). Fifteen healthy volunteers underwent CMR at 3 T, including a four-dimensional phase-contrast flow sequence. Mean LA KE was lower than RA KE (1.1 ± 0.1 vs. 1.7 ± 0.1 mJ, P < 0.01). Three KE peaks were seen in both atria: one in ventricular systole, one during early ventricular diastole, and one during atrial contraction. The systolic LA peak was significantly smaller than the RA peak (P &...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Arvidsson, P. M., Toger, J., Heiberg, E., Carlsson, M., Arheden, H. Tags: ARTICLES Source Type: research

Calpain and caspase-3 play required roles in immobilization-induced limb muscle atrophy
Prolonged skeletal muscle inactivity results in a rapid decrease in fiber size, primarily due to accelerated proteolysis. Although several proteases are known to contribute to disuse muscle atrophy, the ubiquitin proteasome system is often considered the most important proteolytic system during many conditions that promote muscle wasting. Emerging evidence suggests that calpain and caspase-3 may also play key roles in inactivity-induced atrophy of respiratory muscles, but it remains unknown if these proteases are essential for disuse atrophy in limb skeletal muscles. Therefore, we tested the hypothesis that activation of b...
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Authors: Talbert, E. E., Smuder, A. J., Min, K., Kwon, O. S., Powers, S. K. Tags: ARTICLES Source Type: research

Corrigendum
(Source: Journal of Applied Physiology)
Source: Journal of Applied Physiology - May 16, 2013 Category: Physiology Tags: CORRIGENDA Source Type: research