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This page shows you the most recent publications within this specialty of the MedWorm directory.

COGNITION–CHILDHOOD MALTREATMENT INTERACTIONS IN THE PREDICTION OF ANTIDEPRESSANT OUTCOMES IN MAJOR DEPRESSIVE DISORDER PATIENTS: RESULTS FROM THE iSPOT‐D TRIAL
ConclusionsThe effect of CM on prefrontal circuitry involved in executive function is a potential predictor of antidepressant outcomes. (Source: Depression and Anxiety)
Source: Depression and Anxiety - April 28, 2015 Category: Psychiatry Authors: Shefali Miller, Lisa M. McTeague, Anett Gyurak, Brian Patenaude, Leanne M. Williams, Stuart M. Grieve, Mayuresh S. Korgaonkar, Amit Etkin Tags: Research Article Source Type: research

Functional and Structural Remodeling of Glutamate Synapses in Prefrontal and Frontal Cortex Induced by Behavioral Stress
Laura Musazzi, Giulia Treccani and Maurizio Popoli (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 28, 2015 Category: Psychiatry Source Type: research

The ‘disconnect’ between initial judgments of lamotrigine vs. its real‐world effectiveness in managing bipolar disorder. A tale with wider ramifications
ConclusionThe lamotrigine disconnect story provides a number of salutary lessons that are salient to evaluating the effectiveness and ecological niche of any psychotropic medication. The lamotrigine story presented here argues strongly for the wisdom of encouraging an iterative process between efficacy studies and clinical observation. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - April 28, 2015 Category: Psychiatry Authors: G. Parker, S. McCraw Tags: Clinical Overview Source Type: research

Prevention of homicidal behaviour in men with psychiatric disorders
The World Journal of Biological Psychiatry, Ahead of Print. (Source: World Journal of Biological Psychiatry)
Source: World Journal of Biological Psychiatry - April 28, 2015 Category: Psychiatry Tags: article Source Type: research

Effects of sodium butyrate on aversive memory in rats submitted to sepsis
Publication date: 19 May 2015 Source:Neuroscience Letters, Volume 595 Author(s): Amanda V. Steckert , Clarissa M. Comim , Dhébora M. Dall Igna , Diogo Dominguini , Bruna P. Mendonça , Felipe Ornell , Gabriela D. Colpo , Carolina Gubert , Flávio Kapczinski , Tatiana Barichello , João Quevedo , Felipe Dal-Pizzol Epigenetic mechanisms are involved in normal behavior and are implicated in several brain neurodegenerative conditions, psychiatric and inflammatory diseases as well. Moreover, it has been demonstrated that sepsis lead to an imbalance in acetylation of histones and that histone deacetylase inhibitors (HDACi) ca...
Source: Neuroscience Letters - April 28, 2015 Category: Neuroscience Source Type: research

Baclofen as relapse prevention in the treatment of Gamma- Hydroxybutyrate (GHB) dependence: an open label study
DiscussionIt is hypothesized that baclofen treatment compared to TAU will be associated with significantly reduced GHB use. In addition, we hypothesize that baclofen treatment will be associated with decreased craving and anxiety levels, and higher quality of life. If results are in line with our hypotheses, further studies on the efficacy of baclofen using placebo controlled designs and long term follow-up are warranted.Trial registrationThe Netherlands Trial Register with number NTR4528. Registered 19 April 2014. (Source: BMC Psychiatry)
Source: BMC Psychiatry - April 28, 2015 Category: Psychiatry Authors: Rama KamalArnt SchellekensCornelis De JongBoukje Dijkstra Source Type: research

Aberrant high frequency oscillations recorded in the rat nucleus accumbens in the methylazoxymethanol acetate neurodevelopmental model of schizophrenia
Conclusion Together these findings suggest that increased HFO frequency represents an important feature in certain animal models of schizophrenia. These findings support the hypothesis that altered functioning of the NAc is a core feature in animal models of schizophrenia. (Source: Progress in Neuro Psychopharmacology and Biological Psychiatry)
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - April 28, 2015 Category: Psychiatry Source Type: research

Effect of metabotropic glutamate receptor-3 variants on prefrontal brain activity in schizophrenia: An imaging genetics study using multi-channel near-infrared spectroscopy
Discussion The rs274622 C carriers with schizophrenia were associated with significantly smaller prefrontal activation than patients with TT genotype. This between-genotype difference tended to be confined to the patient group. GRM3 polymorphisms are associated with prefrontal activation during cognitive task in schizophrenia. (Source: Progress in Neuro Psychopharmacology and Biological Psychiatry)
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - April 28, 2015 Category: Psychiatry Source Type: research

Stress is a principal factor that promotes tobacco use in females
Publication date: Available online 22 April 2015 Source:Progress in Neuro-Psychopharmacology and Biological Psychiatry Author(s): Oscar V. Torres , Laura E. O'Dell Tobacco use is a major economic and health problem. It is particularly concerning that women consume more tobacco products, have a more difficult time quitting smoking and are less likely to benefit from smoking cessation therapy than men. As a result, women are at higher risk of developing tobacco-related diseases. Clinical evidence suggests that women are more susceptible to anxiety disorders, and are more likely to smoke in order to cope with stress than me...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - April 28, 2015 Category: Psychiatry Source Type: research

Amphetamine and other pharmacological agents in human and animal studies of recovery from stroke
Publication date: Available online 18 April 2015 Source:Progress in Neuro-Psychopharmacology and Biological Psychiatry Author(s): D. Walker-Batson , J. Mehta , P. Smith , M. Johnson Neuromodulation with pharmacological agents, including drugs of abuse such as amphetamine, when paired with behavioral experience, has been shown to positively modify outcomes in animal models of stroke. A number of clinical studies have tested the efficacy of a variety of drugs to enhance recovery of language deficit post-stroke. The purpose of this paper is to: (1) present pertinent animal studies supporting the use of dextro-amphetamine su...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - April 28, 2015 Category: Psychiatry Source Type: research

The NVL gene confers risk for both major depressive disorder and schizophrenia in the Han Chinese population
Publication date: Available online 17 April 2015 Source:Progress in Neuro-Psychopharmacology and Biological Psychiatry Author(s): Meng Wang , Jianhua Chen , Kuanjun He , Qingzhong Wang , Zhiqiang Li , Jiawei Shen , Zujia Wen , Zhijian Song , Yifeng Xu , Yongyong Shi NVL (nuclear VCP (valosin containing protein)/p97-Like), a member of the AAA-ATPase (ATPases associated with various cellular activities) family, encodes a novel hTERT (human telomerase reverse transcriptase)-interacting protein NVL2 which is a telomerase component essential for holoenzyme assembly. Previous researches have reported the impacts of telomerase ...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - April 28, 2015 Category: Psychiatry Source Type: research

Animal models of major depression and their clinical implications
Publication date: Available online 17 April 2015 Source:Progress in Neuro-Psychopharmacology and Biological Psychiatry Author(s): Boldizsár Czéh , Eberhard Fuchs , Ove Wiborg , Mária Simon Major depressive disorder is a common, complex, and potentially life-threatening mental disorder that imposes a severe social and economic burden worldwide. Over the years, numerous animal models have been established to elucidate pathophysiology that underlies depression and to test novel antidepressant treatment strategies. Despite these substantial efforts, the animal models available currently are of limited utility for these pu...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - April 28, 2015 Category: Psychiatry Source Type: research

Partial agonism and fast dissociation of LASSBio-579 at dopamine D2 receptor
Publication date: Available online 17 April 2015 Source:Progress in Neuro-Psychopharmacology and Biological Psychiatry Author(s): Thais Emanoelle T. Pompeu , Fernando Monteiro do Monte , Barbara Bosier , Carlos A.M. Fraga , Eliezer J. Barreiro , Ricardo Menegatti , Emmanuel Hermans , François Noël In an attempt to better understand the molecular mechanism of action of the antipsychotic lead LASSBio-579 and of its main metabolite LQFM 037, the aim of this work was to evaluate their intrinsic activity and binding kinetics at the dopamine D2 receptor. In transfected HEK cells expressing the D2L receptor under an inducible...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - April 28, 2015 Category: Psychiatry Source Type: research

Potential of the cannabinoid CB2 receptor as a pharmacological target against inflammation in Parkinson's disease
In conclusion, we have provided the first evidence on the up-regulation of CB2 receptors in glial elements in postmortem tissues of PD patients, which has been confirmed in an inflammatory model of this disease. In addition, we have provided evidence on the benefits derived from their activation in relation with the activation of microglial cells, the infiltration of macrophages and also certain capability of these cells to generate proinflammatory factors. (Source: Progress in Neuro Psychopharmacology and Biological Psychiatry)
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - April 28, 2015 Category: Psychiatry Source Type: research

Making (anti-) sense out of huntingtin levels in Huntington disease
Conclusions: We found small differences in allelic huntingtin mRNA levels in adult-onset HD brain, with significantly lower mutant huntingtin mRNA levels. Wild-type and mutant huntingtin protein were not significantly different in adult-onset HD brain samples. Conversely, in juvenile HD brain samples mutant huntingtin protein levels were lower compared with wild-type huntingtin, showing subtle differences between juvenile HD and adult-onset HD. Since most HD model systems harbor juvenile repeat expansions, our results suggest caution with the interpretation of huntingtin mRNA and protein studies using HD cell and animal mo...
Source: Epidemiologic Perspectives and Innovations - April 27, 2015 Category: Epidemiology Authors: Melvin M EversMenno H SchutBarry A PepersMelek AtalarMartine J van BelzenRichard FaullRaymund RoosWilleke van Roon-Mom Source Type: research

Postsecondary study and mental ill-health: a meta-synthesis of qualitative research exploring students’ lived experiences
Journal of Mental Health, Volume 24, Issue 2, Page 111-119, April 2015. (Source: Journal of Mental Health)
Source: Journal of Mental Health - April 27, 2015 Category: Psychiatry Tags: article Source Type: research

Book Review
Journal of Mental Health, Volume 24, Issue 2, Page 122-122, April 2015. (Source: Journal of Mental Health)
Source: Journal of Mental Health - April 27, 2015 Category: Psychiatry Tags: book review Source Type: research

Consumer perspectives on the therapeutic value of a psychiatric environment
Journal of Mental Health, Volume 24, Issue 2, Page 63-67, April 2015. (Source: Journal of Mental Health)
Source: Journal of Mental Health - April 27, 2015 Category: Psychiatry Tags: article Source Type: research

Book Review
Journal of Mental Health, Volume 24, Issue 2, Page 120-120, April 2015. (Source: Journal of Mental Health)
Source: Journal of Mental Health - April 27, 2015 Category: Psychiatry Tags: book review Source Type: research

Book Review
Journal of Mental Health, Volume 24, Issue 2, Page 121-121, April 2015. (Source: Journal of Mental Health)
Source: Journal of Mental Health - April 27, 2015 Category: Psychiatry Tags: book review Source Type: research

“Work is good for me”: views of mental health service users seeking work during the UK recession, a qualitative analysis
Journal of Mental Health, Volume 24, Issue 2, Page 93-97, April 2015. (Source: Journal of Mental Health)
Source: Journal of Mental Health - April 27, 2015 Category: Psychiatry Tags: article Source Type: research

Home treatment teams: what should they do? A qualitative study of patient opinions
Journal of Mental Health, Volume 24, Issue 2, Page 98-102, April 2015. (Source: Journal of Mental Health)
Source: Journal of Mental Health - April 27, 2015 Category: Psychiatry Tags: article Source Type: research

“We all go a little mad sometimes”: the problematic depiction of psychotic and psychopathic disorders in cinema
Journal of Mental Health, Volume 24, Issue 2, Page 61-62, April 2015. (Source: Journal of Mental Health)
Source: Journal of Mental Health - April 27, 2015 Category: Psychiatry Tags: article Source Type: research

Does Artificial Food Coloring Contribute to ADHD in Children?
The FDA maintains dyes are safe, but some studies have linked them to hyperactivity in children -- Read more on ScientificAmerican.com (Source: Scientific American - Official RSS Feed)
Source: Scientific American - Official RSS Feed - April 27, 2015 Category: Science Tags: More Science Biology Chemistry Society & Policy Health Mind Brain Psychiatry Source Type: research

Hypochondriasis as an early manifestation of dementia with Lewy bodies: an autopsied case report
Abstract Discrepancies between clinical and pathological diagnoses of dementia with Lewy bodies (DLB) may occur because the full disease progression remains unclear, especially during the early stage. Herein, we report the case of a 78‐year‐old Japanese man with hypochondriasis who had autopsy‐confirmed limbic‐type DLB pathology. He exhibited no core clinical features of DLB. We attempted to identify the clinicopathological correlations in the early stages of DLB. At the age of 77, he became hypochondriacal and exhibited progressive cognitive decline after the death of his wife. He was concerned about his poor phys...
Source: Psychogeriatrics - April 27, 2015 Category: Geriatrics Authors: Hiroshige Fujishiro, Shuji Iritani, Hirotaka Sekiguchi, Chikako Habuchi, Youta Torii, Shinji Matsunaga, Norio Ozaki, Mari Yoshida, Kiyoshi Fujita Tags: Case Report Source Type: research

Secondary mania due to AIDS and cryptococcal meningitis in a 78‐year‐old patient
We report a 78‐year‐old man without past psychiatric history who experienced his first manic episode successfully treated with quetiapine and lorazepam, but was ultimately found to have AIDS and Cryptococcus neoformans meningitis. Our presented case highlights the importance of comprehensive differential diagnoses to rule out secondary causes of psychiatric symptoms presenting for the first time in elderly patients. (Source: Psychogeriatrics)
Source: Psychogeriatrics - April 27, 2015 Category: Geriatrics Authors: Po‐Han Chou, Wen‐Chen Ouyang, Tsuo‐Hung Lan, Chin‐Hong Chan Tags: Case Report Source Type: research

Presenile onset of spinocerebellar ataxia type 1 presenting with conspicuous psychiatric symptoms and widespread anti‐expanded polyglutamine antibody‐ and fused in sarcoma antibody‐immunopositive pathology
Abstract A 50‐year‐old Japanese man showed slowly progressive gait disturbance and dysarthria. Neurological examination 5 years after onset revealed slow eye movement with nystagmus as well as limb and truncal ataxia. Magnetic resonance imaging showed atrophy of the cerebellum and brainstem. Because genetic examination revealed CAG repeat expansion of the ataxin‐1 gene, the patient was diagnosed with spinocerebellar ataxia type 1. Ten years after onset, he showed psychiatric symptoms with cognitive impairment, and antipsychotic drugs were administered. As psychiatric symptoms gradually worsened, particularly with reg...
Source: Psychogeriatrics - April 27, 2015 Category: Geriatrics Authors: Yasushi Iwasaki, Keiko Mori, Masumi Ito, Maya Mimuro, Mari Yoshida Tags: Case Report Source Type: research

Antipsychotics can induce pre‐shock in very elderly patients: a report of two cases
We report two cases of very elderly patients who developed pre‐shock after the administration of antipsychotics in a clinical consultation‐liaison setting. These cases suggest that antipsychotics can induce fatal adverse events in very elderly patients. Although there has been little evidence regarding the most appropriate kind of drug and dosage for such patients, psychiatrists should exercise great caution in the use of antipsychotics for the very elderly, including deciding to prescribe the lowest dose or not prescribing them at all. (Source: Psychogeriatrics)
Source: Psychogeriatrics - April 27, 2015 Category: Geriatrics Authors: Satoshi Ueda, Ataru Omori, Touko Shioya, Yoshiro Okubo Tags: Case Report Source Type: research

A comparative analysis of dementia inpatient characteristics: results from a nationwide survey of different care facilities in Japan
ConclusionResult showed that dementia patients in psychiatric hospitals had a higher proportion of men, younger age groups, and severe dementia than other types of facilities. These features contrast markedly with status of dementia patients in other Long‐Term Care Insurance care facilities. In order to facilitate dementia patients' early discharge from psychiatric hospitals to other care facilities or to home, further fulfilment care services corresponding to severe dementia and early‐onset dementia may be needed. (Source: Psychogeriatrics)
Source: Psychogeriatrics - April 27, 2015 Category: Geriatrics Authors: Atsuko Yoshimura, Adam Lebowitz, Shogyoku Bun, Miyuki Aiba, Chiaki Ikejima, Takashi Asada Tags: Original Article Source Type: research

Letter From Stockholm
Some of the ideas of Sigmund Freud were preceded in a literary form by the Swedish writer August Strindberg in the late 19th century. Psychoanalysis itself was introduced in Sweden about a decade into the 20th century by two rivalling pioneers, the doctors Emanuel af Geijerstam and Poul Bjerre. After a slow start, the Danish‐Norwegian Psychoanalytical Society and the Finnish‐Swedish Psychoanalytical Society were formed in 1934 in Stockholm. The same year, Ericastiftelsen [The Erica Foundation], a psychotherapeutic clinic for children, was founded by Hanna Bratt. Five years later, in 1939, also in Stockholm, the organiz...
Source: The International Journal of Psychoanalysis - April 27, 2015 Category: Psychiatry & Psychology Authors: Per Magnus Johansson Tags: Letter From Source Type: research

Black Celebrities, Selfhood, and Psychiatry in the Civil Rights Era: The Wiltwyck School for Boys and the Floyd Patterson House
This paper contends that a color-blind psychologisation of black interiority constituted one way in which activists imagined African Americans as both fully human and deserving of equal citizenship during the long civil rights era. Between 1954 and 1964, the Wiltwyck School for Boys, a reform school with a predominantly black student body in Esopus, New York, expanded their therapeutic services into Manhattan, creating one of the US's first psychiatric aftercare programmes. Singer Harry Belafonte and boxing champion Floyd Patterson, two black culture heroes linked to the civil rights movement, lent their support as the Wil...
Source: Social History of Medicine - April 27, 2015 Category: History of Medicine Authors: Doyle, D. A. Tags: Original Articles Source Type: research

Bipartisan bill reauthorizes mental health, criminal justice collaboration law
(Source: Mental Health Weekly)
Source: Mental Health Weekly - April 27, 2015 Category: Psychiatry Authors: Valerie A. Canady Tags: Articles Source Type: research

MH providers urged to consider nontypical partners in crisis care
(Source: Mental Health Weekly)
Source: Mental Health Weekly - April 27, 2015 Category: Psychiatry Authors: Gary Enos Tags: Article Source Type: research

FQHC look‐alikes working to provide PC to underserved groups
(Source: Mental Health Weekly)
Source: Mental Health Weekly - April 27, 2015 Category: Psychiatry Authors: Valerie A. Canady Tags: Articles Source Type: research

National guidelines released to help people facing suicide loss
(Source: Mental Health Weekly)
Source: Mental Health Weekly - April 27, 2015 Category: Psychiatry Authors: Valerie A. Canady Tags: Articles Source Type: research

Core competencies for peers available for public comment
(Source: Mental Health Weekly)
Source: Mental Health Weekly - April 27, 2015 Category: Psychiatry Authors: Valerie A. Canady Tags: Articles Source Type: research

Briefly Noted
(Source: Mental Health Weekly)
Source: Mental Health Weekly - April 27, 2015 Category: Psychiatry Tags: Briefly Noted Source Type: research