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Crossing the Boundaries of Privacy in Accidental Encounters: Interpretative Phenomenological Analysis of Therapists' Experiences.
Authors: Pietkiewicz IJ, Włodarczyk M Abstract This qualitative study explores psychodynamic therapists' experiences associated with unexpected encounters with their patients outside the clinical setting. Information was collected using a semi-structured interview protocol from 10 experienced practitioners in Poland and examined according to the interpretative phenomenological analysis principles. Four overarching themes are discussed in the paper. Results show that accidental encounters often challenged practitioners' privacy, led to involuntary self-disclosure (causing discomfort and distress) and required re-ne...
Source: Clinical Psychology and Psychotherapy - October 31, 2014 Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research

The Other Side of the Broken Window: A Methodology that Translates Building Permits into an Ecometric of Investment by Community Members.
Authors: O'Brien DT, Montgomery BW Abstract Much research has focused on physical disorder in urban neighborhoods as evidence that the community does not maintain local norms and spaces. Little attention has been paid to the opposite: indicators of proactive investment in the neighborhood's upkeep. This manuscript presents a methodology that translates a database of approved building permits into an ecometric of investment by community members, establishing basic content, criteria for reliability, and construct validity. A database from Boston, MA contained 150,493 permits spanning 2.5 years, each record including...
Source: American Journal of Community Psychology - October 31, 2014 Category: Psychiatry Tags: Am J Community Psychol Source Type: research

How Does Stress-Induced Activation of the Kappa Opioid System Increase Addiction Risk?
In their article in this issue of Biological Psychiatry, Polter et al. (1) show that cold-water swim stress exposure blocks long-term potentiation of GABAergic synaptic input (LTPGABA) recorded in ventral tegmental area (VTA) dopamine neurons of male Sprague-Dawley rats. The effects of stress exposure on LTPGABA were blocked by pretreatment with the glucocorticoid antagonist RU-486 or the kappa opioid receptor (KOR) antagonist norbinaltorphimine (norBNI). When norBNI was given 4 days after stress exposure, it reversed the effects of swim stress on LTPGABA and blocked stress-induced reinstatement of cocaine self-administrat...
Source: Biological Psychiatry - October 31, 2014 Category: Psychiatry Authors: Charles Chavkin, Jonathan M. Ehrich Tags: Commentary Source Type: research

Reductions of p11 and 5-HT1B Receptor Availability in Limbic Brain Regions in Cocaine Dependence
Results from the 2012 National Survey on Drug Use and Health reported that approximately 1.6 million individuals aged 12 or over are cocaine abusers in the United States (1). In addition, cocaine abusers often have comorbid disorders, and it has been estimated that 30% to 40% of individuals suffering from drug abuse have a mood or anxiety disorder (2). The high rate of comorbidity between mood disorders and cocaine dependence suggests shared anatomical pathways and molecular mechanisms. Accordingly, it has been reported that both depression and cocaine dependence are associated with alterations in the reward circuitry of t...
Source: Biological Psychiatry - October 31, 2014 Category: Psychiatry Authors: Per Svenningsson Tags: Commentary Source Type: research

More Cocaine—More Glutamate—More Addiction
Over the last 15 years, animal models of cocaine reinforcement and reinstated drug seeking have pointed to the involvement of nucleus accumbens dopamine and glutamate neurotransmission in regulating drug intake and drug seeking, respectively (1,2). For reinstated drug seeking, evidence supporting glutamate transmission in the core subcompartment of the accumbens (NAcore) is conclusive, including: 1) α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor antagonists prevent reinstatement of cocaine seeking; and 2) there exist enduring neuroadaptations in glutamate transmission, such as downregulated glutamat...
Source: Biological Psychiatry - October 31, 2014 Category: Psychiatry Authors: Cassandra D. Gipson, Peter W. Kalivas Tags: Commentary Source Type: research

Table of Contents
(Source: Biological Psychiatry)
Source: Biological Psychiatry - October 31, 2014 Category: Psychiatry Source Type: research

Subscribers Page
(Source: Biological Psychiatry)
Source: Biological Psychiatry - October 31, 2014 Category: Psychiatry Source Type: research

Editorial Board Page
(Source: Biological Psychiatry)
Source: Biological Psychiatry - October 31, 2014 Category: Psychiatry Source Type: research

A brief summary of the articles appearing in this issue of .
Glück et al. (767–774) evaluated the involvement of G protein-coupled receptor kinases (GRKs) in opioid dependence and in agonist-selective μ-opioid receptor phosphorylation using GRK-deficient mice. Their findings show that μ-opioid receptor phosphorylation in vivo is regulated by agonist-selective recruitment of distinct GRK isoforms that, in turn, influence different opioid-related behaviors. These findings suggest that modulation of GRK function may serve as a potential new approach for preventing opioid addiction, while retaining the clinical benefits of opioid drugs. (Source: Biological Psychiatry)
Source: Biological Psychiatry - October 31, 2014 Category: Psychiatry Tags: In This Issue Source Type: research

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An error in the text has been discovered in the commentary “Deep Repetitive Transcranial Magnetic Stimulation for Smoking Cessation: Is Going Deeper Better?” by Barr and George (2014;76:678–680). The affected section of incorrect text begins on the 5th line of the second paragraph and currently states “… employing the H-coil, which has been shown to target brain regions approximately 5–7 cm deep. This focal depth with the H-coil is very exciting…”. The corrected version of this text is as follows: “ … employing the H-coil, which has been shown to target brain regions up to approximately 3–4 cm deep. (...
Source: Biological Psychiatry - October 31, 2014 Category: Psychiatry Tags: Erratum Source Type: research

Manuscript Submission Form
(Source: Biological Psychiatry)
Source: Biological Psychiatry - October 31, 2014 Category: Psychiatry Source Type: research

Guide for Authors
(Source: Biological Psychiatry)
Source: Biological Psychiatry - October 31, 2014 Category: Psychiatry Source Type: research

A cross‐sectional study of thyroid function in 66 patients with bipolar disorder receiving lithium for 10–44 years
ConclusionsThese results confirm the greater susceptibility of female subjects for disturbances of thyroid hormones during lithium therapy, with one‐fifth of them showing some features of hypothyroidism. Abnormally high levels of anti‐TPO and anti‐TG antibodies were shown in a significant proportion of patients. However, in contrast to the effect of lithium on kidney function, our results do not show an association between the duration of lithium therapy and thyroid dysfunction. (Source: Bipolar Disorders)
Source: Bipolar Disorders - October 31, 2014 Category: Psychiatry Authors: Agnieszka Kraszewska, Maria Chlopocka‐Wozniak, Maria Abramowicz, Jerzy Sowinski, Janusz K Rybakowski Tags: Original Article Source Type: research

Using self‐reported callous‐unemotional traits to cross‐nationally assess the DSM‐5 ‘With Limited Prosocial Emotions’ specifier
ConclusionsRefined self‐report scales developed on the basis of IRT findings provided good assessments of most of the symptoms used in the DSM‐5 criteria. These scales may be used as one component of a multimethod assessment of the ‘With Limited Prosocial Emotions’ specifier for Conduct Disorder. (Source: Journal of Child Psychology and Psychiatry)
Source: Journal of Child Psychology and Psychiatry - October 31, 2014 Category: Psychiatry Authors: Eva R. Kimonis, Kostas A. Fanti, Paul J. Frick, Terrie E. Moffitt, Cecilia Essau, Patricia Bijttebier, Monica A. Marsee Tags: Original Article Source Type: research

Meta‐analysis of the association between suicidal ideation and later suicide among patients with either a schizophrenia spectrum psychosis or a mood disorder
ConclusionAlthough our findings suggest that the association between suicidal ideation and later suicide is stronger in schizophrenia spectrum psychosis than in mood disorders this result should be interpreted cautiously due to the high degree of between‐study heterogeneity and because studies that used stronger methods of reporting had a weaker association between suicidal ideation and suicide. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - October 31, 2014 Category: Psychiatry Authors: C. L. Chapman, K. Mullin, C. J. Ryan, A. Kuffel, O. Nielssen, M. M. Large Tags: Meta‐analysis Source Type: research

Increased prefrontal hemodynamic change after atomoxetine administration in pediatric attention‐deficit/hyperactivity disorder as measured by near‐infrared spectroscopy
ConclusionsThis increase in oxyhemoglobin changes might indicate an intensified prefrontal hemodynamic response induced by atomoxetine. Near‐infrared spectroscopy is a sensitive tool for measuring the pharmacological effects of atomoxetine in children with attention‐deficit/hyperactivity disorder. (Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - October 31, 2014 Category: Neuroscience Authors: Toyosaku Ota, Junzo Iida, Yoko Nakanishi, Satomi Sawada, Hiroki Matsuura, Kazuhiko Yamamuro, Shotaro Ueda, Mitsuhiro Uratani, Naoko Kishimoto, Hideki Negoro, Toshifumi Kishimoto Tags: Regular Article Source Type: research

Annual Research Review: Attachment disorders in early childhood – clinical presentation, causes, correlates, and treatment
ConclusionsAlthough many questions remain to be answered, especially regarding appropriate interventions, we know considerably more about attachment disorders than we did only a decade ago. (Source: Journal of Child Psychology and Psychiatry)
Source: Journal of Child Psychology and Psychiatry - October 31, 2014 Category: Psychiatry Authors: Charles H. Zeanah, Mary Margaret Gleason Tags: Annual Research Review Source Type: research

Age of onset and the subclassification of conduct/dissocial disorder
ConclusionsPhenotypic findings differentiated between childhood‐onset and adolescent‐onset CD. ADHD and family dysfunction predicted persistence of antisocial behavior into young adulthood. (Source: Journal of Child Psychology and Psychiatry)
Source: Journal of Child Psychology and Psychiatry - October 31, 2014 Category: Psychiatry Authors: Judy Silberg, Ashlee A. Moore, Michael Rutter Tags: Original Article Source Type: research

The circadian system of patients with bipolar disorder differs in episodes of mania and depression
ConclusionsThe data revealed differences in the functional state of the circadian system in patients with bipolar disorder depending on whether they were experiencing a manic or a depressive episode. (Source: Bipolar Disorders)
Source: Bipolar Disorders - October 31, 2014 Category: Psychiatry Authors: Marta Nováková, Ján Praško, Klára Látalová, Martin Sládek, Alena Sumová Tags: Original Article Source Type: research

Neurofunctional effects of quetiapine in patients with bipolar mania
ConclusionsThese findings are consistent with suggestions that mania involves a loss of emotional modulatory activity in the prefrontal cortex—restoration of the relatively greater elevation in prefrontal activity widely observed in euthymic patients is associated with clinical improvement. It is not clear, however, whether changes are related to quetiapine treatment or represent a non‐specific marker of affective change. (Source: Bipolar Disorders)
Source: Bipolar Disorders - October 31, 2014 Category: Psychiatry Authors: Andrew K Davis, Melissa P DelBello, James Eliassen, Jeffrey Welge, Thomas J Blom, David E Fleck, Wade A Weber, Kelly B Jarvis, Emily Rummelhoff, Stephen M Strakowski, Caleb M Adler Tags: Brief Report Source Type: research

Screening for alcohol misuse within people attending a psychiatric intellectual disability community service
ConclusionsThe study suggests that alcohol use disorders seem to be a hidden problem within the ID population, existing alongside multiple physical and mental health needs. (Source: Journal of Intellectual Disability Research)
Source: Journal of Intellectual Disability Research - October 30, 2014 Category: Disability Authors: V. Pezzoni, C. Kouimtsidis Tags: Original Article Source Type: research

Lifetime autism spectrum features in a patient with a psychotic mixed episode who attempted suicide.
We present a case report of a young man who attempted suicide during a mixed episode with psychotic symptoms. The patient's history revealed the lifetime presence of signs and features belonging to the autism spectrum realm that had been completely overlooked. We believe that this case is representative of an important and barely researched topic: what happens to children with nondiagnosed and nontreated subthreshold forms of autism when they grow old. The issue of early recognition of autism spectrum signs and symptoms is discussed, raising questions on the diagnostic boundaries between autism and childhood onset psychoti...
Source: Case Reports in Psychiatry - October 30, 2014 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Acknowledgment of Reviewers.
Authors: PMID: 25348639 [PubMed - as supplied by publisher] (Source: American Journal of Community Psychology)
Source: American Journal of Community Psychology - October 30, 2014 Category: Psychiatry Tags: Am J Community Psychol Source Type: research

A Prospective Comparison of Informant-based and Performance-based Dementia Screening Tools to Predict In-Hospital Delirium.
Authors: Zeng L, Josephson SA, Fukuda KA, Neuhaus J, Douglas VC Abstract Dementia is an important risk factor for delirium, but the optimal strategy for incorporating cognitive impairment into delirium risk assessment at the time of hospital admission is unknown. We compared 2 informant-based screening tools for dementia and mild cognitive impairment [AD8 and D=(MC)] to the Mini Mental State Examination (MMSE) and Mini-cog in predicting hospital-acquired delirium. This prospective cohort study at an academic medical center consisted of 162 medical inpatients over age 50 years without delirium upon admission. Each p...
Source: Alzheimer Disease and Associated Disorders - October 30, 2014 Category: Psychiatry Tags: Alzheimer Dis Assoc Disord Source Type: research

Early parent–child relationships and risk of mood disorder in a Canadian sample of offspring of a parent with bipolar disorder: findings from a 16‐year prospective cohort study
ConclusionsNeglect from mother is a significant early predictor of mood disorder in offspring at familial risk for BD and may increase emotional sensitivity. Psychosocial support and interventions for high‐risk families could be beneficial in reducing early adversity, maternal neglect and the risk of subsequent mood disorders in offspring. (Source: Early Intervention in Psychiatry)
Source: Early Intervention in Psychiatry - October 30, 2014 Category: Psychiatry Authors: Sarah Doucette, Adrian Levy, Gordon Flowerdew, Julie Horrocks, Paul Grof, Mark Ellenbogen, Anne Duffy Tags: Original Article Source Type: research

Sleep problems predict comorbid externalizing behaviors and depression in young adolescents with attention-deficit/hyperactivity disorder
This study provides an initial examination of the 1-year prospective association between sleep problems and comorbid symptoms in youth diagnosed with ADHD. Participants were 81 young adolescents (75 % male) carefully diagnosed with ADHD and their parents. Parents completed measures of their child’s sleep problems and ADHD symptoms, oppositional defiant disorder (ODD) symptoms, and general externalizing behavior problems at baseline (M age = 12.2) and externalizing behaviors were assessed again 1 year later. Adolescents completed measures of anxiety and depression at both time-points. Medication use was not ...
Source: European Child and Adolescent Psychiatry - October 30, 2014 Category: Psychiatry Source Type: research

Striatal dopamine D1 and D2 receptors are differentially regulated following buprenorphine or methadone treatment
Conclusions Our results demonstrated that methadone and buprenorphine were able to differentially regulate dopamine receptor density depending on the withdrawal period and the administration pattern. (Source: Psychopharmacology)
Source: Psychopharmacology - October 30, 2014 Category: Psychiatry Source Type: research

The effects of post-extinction exercise on cocaine-primed and stress-induced reinstatement of cocaine seeking in rats
Conclusion These results indicate that chronic wheel running can attenuate some forms of reinstatement, even when initiated after the cessation of cocaine self-administration, supporting the idea that voluntary exercise programs may help maintain abstinence in clinical populations. (Source: Psychopharmacology)
Source: Psychopharmacology - October 30, 2014 Category: Psychiatry Source Type: research

Estimating the burden of psychiatric disorders in adolescence: the impact of subthreshold disorders
Conclusion The results indicate that SUB disorders constitute a major public health burden in terms of psychiatric morbidity among adolescents. Given their substantial impairment and their high prevalence, consideration should be given to including SUB disorders in estimates of the public health burden psychiatric morbidity. Doing so would provide a more accurate estimate of psychiatric morbidity. (Source: Social Psychiatry and Psychiatric Epidemiology)
Source: Social Psychiatry and Psychiatric Epidemiology - October 30, 2014 Category: Psychiatry Source Type: research

Evaluating Patient Acceptability of a Culturally Focused Psychiatric Consultation Intervention for Latino Americans with Depression
Abstract Significant disparities exist in both access to and quality of mental health care for Latino Americans with depression compared to Caucasians, resulting in a greater burden of disability in this underserved population. Our aim is to evaluate participant acceptability of a Culturally Focused Psychiatric (CFP) consultation program for depressed Latino Americans. Latino American adult primary care patients endorsing depressive symptoms on a screening questionnaire were targeted in their primary care clinic. The intervention addressed participants’ depressive symptoms using culturally adapted clinical asse...
Source: Journal of Immigrant and Minority Health - October 30, 2014 Category: Global & Universal Source Type: research

Detecting Depression in Pregnancy: Validation of EPDS in British Pakistani Mothers
Abstract Recent reports suggest that antenatal depression is as prevalent as postnatal depression. The Edinburgh Postnatal Depression Scale (EPDS) is the most widely used tool to detect postnatal depression, which can also detect depression during the antenatal period. Mothers of Pakistani origin have the highest birth rate in the UK. The validity of EPDS has not been assessed in this group. A prospective cohort of 714 women in their third trimester of pregnancy completed the EPDS while waiting for their antenatal visit. Women scoring 12 or more on the EPDS, and a random sample of low scores were assessed with th...
Source: Journal of Immigrant and Minority Health - October 30, 2014 Category: Global & Universal Source Type: research