Psychiatry Research This is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 11.
Comorbidities and Mortality in Persons With Schizophrenia: A Swedish National Cohort Study.
CONCLUSIONS Schizophrenia patients had markedly premature mortality, and the leading causes were ischemic heart disease and cancer, which appeared to be underdiagnosed. Preventive interventions should prioritize primary health care tailored to this population, including more effective risk modification and screening for cardiovascular disease and cancer. PMID: 23318474 [PubMed - as supplied by publisher]
Source: The American Journal of Psychiatry - January 15, 2013 Category: Psychiatry Authors: Crump C, Winkleby MA, Sundquist K, Sundquist J Tags: Am J Psychiatry Source Type: research
Association Between Maternal Depressogenic Cognitive Style During Pregnancy and Offspring Cognitive Style 18 Years Later.
CONCLUSIONS Although the mechanisms remain to be elucidated, the findings are consistent with the idea that a mother's cognitive style (irrespective of her depression status) influences that of her child. This suggests that interventions to improve a mother's cognitive style could help prevent her offspring from developing depression during adulthood. PMID: 23318526 [PubMed - as supplied by publisher]
Source: The American Journal of Psychiatry - January 15, 2013 Category: Psychiatry Authors: Pearson RM, Fernyhough C, Bentall R, Evans J, Heron J, Joinson C, Stein AL, Lewis G Tags: Am J Psychiatry Source Type: research
Perinatal Choline Effects on Neonatal Pathophysiology Related to Later Schizophrenia Risk.
CONCLUSIONS Neonatal developmental delay in inhibition is associated with attentional problems as the child matures. Perinatal choline activates timely development of cerebral inhibition, even in the presence of gene mutations that otherwise delay it. PMID: 23318559 [PubMed - as supplied by publisher]
Source: The American Journal of Psychiatry - January 15, 2013 Category: Psychiatry Authors: Ross RG, Hunter SK, McCarthy L, Beuler J, Hutchison AK, Wagner BD, Leonard S, Stevens KE, Freedman R Tags: Am J Psychiatry Source Type: research
Symptomiatry: Interdisciplinary scope and implications.
PMID: 23322912 [PubMed - as supplied by publisher]
Source: The Australian and New Zealand Journal of Psychiatry - January 15, 2013 Category: Psychiatry Authors: Hassan I Tags: Aust N Z J Psychiatry Source Type: research
Sleep-wake patterns in schizophrenia patients compared to healthy controls.
Conclusion. Schizophrenia patients have more disturbed sleep-wake patterns and poor sleep quality and quality of life compared with healthy controls. PMID: 23316764 [PubMed - as supplied by publisher]
Source: The World Journal of Biological Psychiatry - January 15, 2013 Category: Psychiatry Authors: Afonso P, Figueira ML, Paiva T Tags: World J Biol Psychiatry Source Type: research
Development of metaphors to explain cognitive behavioural principles for patients with medically unexplained symptoms in Sri Lanka.
DISCUSSION: Metaphor is an effective clinical tool. The author's clinical experience and patients' feedback suggest that these metaphors are helpful in conveying the CBT principles to patients. To develop metaphors appealing to the client and effective clinically, carrying out qualitative research among patients' explanatory model is an important prerequisite. The generic and MUS-specific metaphors reported here should be tried in other cultural and clinical settings and evaluated. Further systematic work including qualitative work for consensus evaluation among CBT experts as well as opinion on user-friendliness of these ...
Source: The International Journal of Social Psychiatry - January 15, 2013 Category: Psychiatry Authors: Sumathipala A Tags: Int J Soc Psychiatry Source Type: research
Safely cared for or empowered in mental health care? Yes, please.
CONCLUSIONS: High-quality services are flexible enough to adjust to users' varying symptoms and needs. PMID: 23321388 [PubMed - as supplied by publisher]
Source: The International Journal of Social Psychiatry - January 15, 2013 Category: Psychiatry Authors: Rise MB, Westerlund H, Bjørgen D, Steinsbekk A Tags: Int J Soc Psychiatry Source Type: research
Review: Interventions for patient transition from hospital to primary care may improve outcomes.
CONCLUSION Several interventions to improve the transition of patient care from hospital to primary care may have positive effects on various processes or patient outcomes.Interventions to improve patient transition from hospital to primary careOutcomesNumber of trialsNumber of trials showing significant positive effects*Information sharingCoordination of careCommunicationPatient status†196 of 1311 of 179 of 17Errors, near-misses, or adverse events‡82 of 71 of 32 of 6Hospital use§207 of 129 of 179 of 18*Out of the number of trials assessing the outcome. Interventions could include ≥ 1 component.†Quality of life, ...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Schectman JM Tags: Ann Intern Med Source Type: research
A single screening for type 2 diabetes in high-risk adults did not reduce mortality over 10 years.
CONCLUSION A single screening for type 2 diabetes in high-risk persons did not reduce mortality over 10 years compared with no screening.Screening vs no screening for type 2 diabetes in high-risk persons‡OutcomesEvent rate/1000 patient-yAt a median 9.6 y of follow-upScreeningNo screeningRRI (95% CI)All-cause mortality10.59.896% (-10 to 24)Cardiovascular mortality3.303.252% (-25 to 37)Cancer mortality4.784.438% (-10 to 29)Diabetes-related mortality0.510.4226% (-25 to 110)‡Abbreviations defined in Glossary. RRI and CI calculated from event rates and hazard ratios (adjusted for clustering) in article. PMID: 23318338 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Mahon J Tags: Ann Intern Med Source Type: research
Professionals' perceptions of and views about vocational rehabilitation for people with psychiatric disabilities.
CONCLUSIONS: These professionals dealt with a complex vocational rehabilitation system; they felt that their organizations' directives and inability to collaborate successfully with other authorities restricted their scope of action and hindered their exercise of good practice. PMID: 23324725 [PubMed - as supplied by publisher]
Source: Work - January 15, 2013 Category: Occupational Health Authors: Hillborg H, Danermark B, Svensson T Tags: Work Source Type: research
Evaluating the impact of imputations for missing participant outcome data in a network meta-analysis.
CONCLUSIONS: Sensitivity analysis to account for missing outcome data and their uncertainty in the NMA can be undertaken by extending the idea of IMOR. In two case examples, we found no differences between the various models due to low missing data rate. In line with previous observations, data carry little information about the reason of missingness. PMID: 23321265 [PubMed - as supplied by publisher]
Source: Clinical Trials - January 15, 2013 Category: Research Authors: Spineli LM, Higgins JP, Cipriani A, Leucht S, Salanti G Tags: Clin Trials Source Type: research
Plasma brain-derived neurotrophic factor levels, learning capacity and cognition in patients with first episode psychosis
Conclusion: Our results suggest that BDNF is associated with the cognitive impairment seen after a FEP. Further investigations of the role of this neurotrophin in the symptoms associated with psychosis onset are warranted.
Source: BMC Psychiatry - Latest articles - January 15, 2013 Category: Psychiatry Authors: Sonia de AzuaCarlos MatuteLaura StertzFernando MosqueraAitor PalominoIris de la RosaSara BarbeitoPatricia VegaFlávio KapczinskiAna González-Pinto Source Type: research
Working alliance and its relationship to outcomes in a randomized controlled trial (RCT) of antipsychotic medication
Conclusion: This is the first study to show that the prescription of depot atypical depot medication is associated with detrimental effects on clinical relationships after 2 years of continual treatment.
Source: BMC Psychiatry - Latest articles - January 15, 2013 Category: Psychiatry Authors: Til WykesDiana RosePaul WilliamsAnthony David Source Type: research
Air ions and mood outcomes: a review and meta-analysis
Conclusions: No consistent influence of positive or negative air ionization on anxiety, mood, relaxation, sleep, and personal comfort measures was observed. Negative air ionization was associated with lower depression scores particularly at the highest exposure level. Future research is needed to evaluate the biological plausibility of this association.
Source: BMC Psychiatry - Latest articles - January 15, 2013 Category: Psychiatry Authors: Vanessa PerezDominik AlexanderWilliam Bailey Source Type: research
Behaviorally based adherence program for pediatric patients treated with positive airway pressure
Conclusions: The program shows some promise and provides a framework for future program development and research.
Source: Clinical Child Psychology and Psychiatry - January 15, 2013 Category: Psychiatry Authors: Harford, K.-L., Jambhekar, S., Com, G., Pruss, K., Kabour, M., Jones, K., Ward, W. L. Tags: Articles Source Type: research
A case of pervasive refusal syndrome: A diagnostic conundrum
A case is presented of an 11-year-old girl with pervasive refusal syndrome (PRS) who ultimately recovered acutely and completely after an 18-month paediatric hospitalisation. There was an apparent absence of previously proposed important aetiological factors in PRS, such as family pathology and markedly traumatic or abusive experiences, and her recovery was sudden and complete. The authors consider the differential diagnoses of PRS paying particular attention to the possibility of a conversion disorder or catatonia, given the absence of PRS in the North American literature. Consideration of catatonia is important as it has...
Source: Clinical Child Psychology and Psychiatry - January 15, 2013 Category: Psychiatry Authors: McNicholas, F., Prior, C., Bates, G. Tags: Articles Source Type: research
Addressing trauma in collaborative mental health care for refugee children
Primary care institutions, including clinics, schools and community organizations, because of their closeness to the family living environment, are often in a privileged position to detect problems in traumatized refugee children and to provide help. In a collaborative care model, the child psychiatrist consultant can assist the primary care consultee and family in holding the trauma narrative and organizing a safe network around the child and family. The consultant can support the establishment of a therapeutic alliance, provide a cultural understanding of presenting problems and negotiate with the consultee and the famil...
Source: Clinical Child Psychology and Psychiatry - January 15, 2013 Category: Psychiatry Authors: Rousseau, C., Measham, T., Nadeau, L. Tags: Articles Source Type: research
Intercepting the intergenerational cycle of maternal trauma and loss through mother-infant psychotherapy: A case study using attachment-derived methods
Some mothers who have recently lost a significant attachment figure may become mentally incoherent and sporadically even enter a trancelike, dissociative state. Such states of mind have been shown to predict infant attachment disorganization. Infants born close to the time of a parental loss are at a greater risk for intergenerational trauma. A background of maternal substance abuse is also known to increase such risk. We illustrate by way of a case study how a mother–infant group psychotherapy programme aimed at substance-abusing mothers may help to prevent the transmission of mother’s unresolved trauma to the...
Source: Clinical Child Psychology and Psychiatry - January 15, 2013 Category: Psychiatry Authors: Belt, R. H., Kouvo, A., Flykt, M., Punamaki, R.-L., Haltigan, J. D., Biringen, Z., Tamminen, T. Tags: Articles Source Type: research
"That must be so hard"- Examining the impact of children's palliative care services on the psychological well-being of parents
In 2003 the New Opportunities Fund (NOF, now known as The Big Lottery) awarded £48 million to 70 home-based care teams to enable them to provide a range of services to allow children with non-malignant life-limiting conditions to be cared for at home. Four grants were made available in Bristol, North Somerset, South Gloucestershire and Bath and North East Somerset to enhance existing children’s palliative care services. As there is limited evidence about the impact of palliative care services on psychological well-being, this study measured parental stress and the psychological wellbeing of parents of newly ref...
Source: Clinical Child Psychology and Psychiatry - January 15, 2013 Category: Psychiatry Authors: Gupta, V., Prescott, H. Tags: Articles Source Type: research
A qualitative exploration into young children's perspectives and understandings of emotional difficulties in other children
Research into children’s perspectives and understandings of emotional difficulties is limited and methodologically varied. In this paper we explore young children’s perspectives and understandings of emotional difficulties in their peers. We conducted five focus groups involving a total of 25 children. The children, aged eight and nine, were presented with vignettes representing peers experiencing emotional difficulties, and invited to discuss their perspectives on possible causes. We also explored their emotional and behavioural reactions to the vignette characters. Using interpretative phenomenological analys...
Source: Clinical Child Psychology and Psychiatry - January 15, 2013 Category: Psychiatry Authors: Dixon, C., Murray, C., Daiches, A. Tags: Articles Source Type: research
Using video feedback to improve early father-infant interaction: A pilot study
Preventive interventions with parents of infants have tended to focus on mothers. Recent research focused on fathers suggests that their involvement in interventions might enhance effectiveness. One effective approach with mothers is the brief, home-based Video-feedback Intervention to promote Positive Parenting (VIPP). This paper is a report of a pilot study of VIPP with fathers to assess its feasibility. Five fathers were recruited from an existing longitudinal study of parents. The primary outcome was acceptability, assessed using a semi-structured questionnaire after completion of the intervention. All fathers complete...
Source: Clinical Child Psychology and Psychiatry - January 15, 2013 Category: Psychiatry Authors: Lawrence, P. J., Davies, B., Ramchandani, P. G. Tags: Articles Source Type: research
I wish I could tell you but I can't: Adolescents with perinatally acquired HIV and their dilemmas around self-disclosure
This study aims to describe and explore the attitudes and opinions of adolescents with perinatally acquired HIV towards disclosure. Semi-structured interviews were conducted with nine young people aged 13–19 and analysed using Interpretative Phenomenological Analysis. Four themes emerged to illuminate the young people’s attitudes towards disclosure. These were 1) myths and assumptions, 2) the disclosure dilemma, 3) fear and 4) keeping HIV in its place. This study confirms that many young people with HIV are choosing not to disclose. However, it appears that it is a complex decision-making process that changes o...
Source: Clinical Child Psychology and Psychiatry - January 15, 2013 Category: Psychiatry Authors: Hogwood, J., Campbell, T., Butler, S. Tags: Articles Source Type: research
A systems relations model for Tier 2 early intervention child mental health services with schools: An exploratory study
Over the last 15 years, policy initiatives have aimed at the provision of more comprehensive Child and Adolescent Mental Health care. These presented a series of new challenges in organising and delivering Tier 2 child mental health services, particularly in schools. This exploratory study aimed to examine and clarify the service model underpinning a Tier 2 child mental health service offering school-based mental health work. Using semi-structured interviews, clinician descriptions of operational experiences were gathered. These were analysed using grounded theory methods. Analysis was validated by respondents at two stage...
Source: Clinical Child Psychology and Psychiatry - January 15, 2013 Category: Psychiatry Authors: van Roosmalen, M., Gardner-Elahi, C., Day, C. Tags: Articles Source Type: research
Against the odds: Foster carers' perceptions of family, commitment and belonging in successful placements
This study examines carer attributes associated with placement stability for teenagers growing up in long term foster care, focusing on unexpected placement success. We explored experiences and perceptions relating to family, belonging and commitment in a group of foster carers providing a stable placement for a young person who had not been expected to settle. These placements showed positive outcome, despite factors in the child’s history that might have predicted otherwise. Seven foster carers were interviewed following a semi-structured guide, which covered their ideas about their relationship with the child in q...
Source: Clinical Child Psychology and Psychiatry - January 15, 2013 Category: Psychiatry Authors: Oke, N., Rostill-Brookes, H., Larkin, M. Tags: Articles Source Type: research
Setting the bar higher: What information do we need to establish the effectiveness of mental health interventions for children with complex attachment- and trauma-related difficulties?
Source: Clinical Child Psychology and Psychiatry - January 15, 2013 Category: Psychiatry Authors: Tarren-Sweeney, M. Tags: Editorial Source Type: research
Risk of pneumonia and pneumococcal disease in people with severe mental illness: English record linkage studies
Conclusions Severe mental illness is a risk factor for lobar pneumonia, pneumococcal pneumonia, pneumococcal septicaemia and meningitis. Possible explanations for the elevated risk include factors relating to lifestyle and health-risk activities. If our findings are replicated elsewhere, there would be a case for considering routine pneumococcal immunisation for people with severe mental illness.
Source: Thorax - January 15, 2013 Category: Respiratory Medicine Authors: Seminog, O. O., Goldacre, M. J. Tags: Pneumonia (infectious disease), TB and other respiratory infections, Vaccination / immunisation, Pneumonia (respiratory medicine) Respiratory epidemiology Source Type: research
Psychoactive bacteria Lactobacillus rhamnosus (JB-1) elicits rapid frequency facilitation in vagal afferents
Mounting evidence supports the influence of the gut microbiome on the local enteric nervous system and its effects on brain chemistry and relevant behavior. Vagal afferents are involved in some of these effects. We previously showed that ingestion of the probiotic bacterium Lactobacillus rhamnosus (JB-1) caused extensive neurochemical changes in the brain and behavior that were abrogated by prior vagotomy. Because information can be transmitted to the brain via primary afferents encoded as neuronal spike trains, our goal was to record those induced by JB-1 in vagal afferents in the mesenteric nerve bundle and thus determin...
Source: AJP: Gastrointestinal and Liver Physiology - January 15, 2013 Category: Gastroenterology Authors: Perez-Burgos, A., Wang, B., Mao, Y.-K., Mistry, B., Neufeld, K.-A. M., Bienenstock, J., Kunze, W. Tags: NEUROREGULATION AND MOTILITY Source Type: research
Light drinking in pregnancy and mid-childhood mental health and learning outcomes
Conclusions Although the pattern of findings involving parent ratings for girls exposed to light drinking is consistent with earlier findings from this cohort, the overall lack of any adverse effects of light drinking is similar to findings from other recent cohort studies. Light drinking in pregnancy does not appear to be associated with clinically important adverse effects for mental health and academic outcomes at the age of 11 years.
Source: Archives of Disease in Childhood - January 15, 2013 Category: Pediatrics Authors: Sayal, K., Draper, E. S., Fraser, R., Barrow, M., Davey Smith, G., Gray, R. Tags: Epidemiologic studies, Open access, Pregnancy, Reproductive medicine, Child and adolescent psychiatry (paedatrics) Original articles Source Type: research
Significant association of CHRNB3 variants with nicotine dependence in multiple ethnic populations
a, T Park & M D Li
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: W Y CuiS WangJ YangS G YiD YoonY-J KimT J PayneJ Z MaT ParkM D Li Source Type: research
Support for association of RORA variant and post traumatic stress symptoms in a population-based study of hurricane exposed adults
& J Gelernter
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: A B AmstadterJ A SumnerR AciernoK J RuggieroK C KoenenD G KilpatrickS GaleaJ Gelernter Source Type: research
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia
r & K F Berman
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: D P EisenbergA M IanniS-M WeiP D KohnB KolachanaJ ApudD R WeinbergerK F Berman Tags: schizophrenia BDNF hippocampus PET Val66Met working memory Source Type: research
Adaptive fitness; early life adversity improves adult stress coping in heterozygous serotonin transporter knockout rats
& J R Homberg
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: R H A van der DoelenT KoziczJ R Homberg Source Type: research
Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid
ff, P Bruins, E M Derks, R S Kahn & R A Ophoff
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: J J LuykxS C BakkerE LentjesM NeelemanE StrengmanL MentinkJ DeYoungS de JongJ H SulE EskinK van EijkJ van SettenJ E Buizer-VoskampR M CantorA LuM van AmerongenE P A van DongenP KeijzersT KappenP BorgdorffP BruinsE M DerksR S KahnR A Ophoff Tags: cerebrospinal fluid CSMD1 genome-wide association study monoamine PDE9A SSTR1 Source Type: research
The multimodal connectivity of the hippocampal complex in auditory and visual hallucinations
homas & R Jardri
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: A AmadA CachiaP GorwoodD PinsC DelmaireB RollandM MondinoP ThomasR Jardri Tags: hallucinations hippocampus MRI neuroplasticity schizophrenia visual Source Type: research
PTSD risk is associated with BDNF Val66Met and BDNF overexpression
Benevides & R J Ursano
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: L ZhangD M BenedekC S FullertonR D ForstenJ A NaifehX X LiX Z HuH LiM JiaG Q XingK N BenevidesR J Ursano Source Type: research
MAOA and mechanisms of panic disorder revisited: from bench to molecular psychotherapy
ng, V Arolt, H-U Wittchen, A Hamm, T Kircher & J Deckert
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: A ReifJ RichterB StraubeM HöflerU LuekenA T GlosterH WeberK DomschkeL FehmA StröhleA JansenA GerlachM PykaI ReinhardtC KonradA WittmannB PfleidererG W AlpersP PauliT LangV AroltH-U WittchenA HammT KircherJ Deckert Tags: behavioral avoidance task fMRI monoamine oxidase A panic disorder promoter polymorphism therapygenetics Source Type: research
News: Libertas joins IPG
We're pleased to announce our latest new industry membership: the Independent Publishers Guild. The IPG is 51 years old and has more than 560 members around the world. We look forward to working with out IPG members and cont...
Source: Autism Insights - January 14, 2013 Category: Psychiatry Source Type: research
News: What's a Tumblr?
Tumblrs are a relatively new innovation in social media. Unlike other manifestations of social media Tumblrs focusses primarily on images. Libertas joined Tumblr relatively recently with the aim of establishing whether it was an...
Source: Autism Insights - January 14, 2013 Category: Psychiatry Source Type: research
Erratum to “The influence of semantic top-down processing in auditory verbal hallucinations” [Schizophr. Res. 139 (1–3) (2012) 82–86]
The author regrets that the following error occurred in the paper above: Page 84, right column, paragraph 3.2, line 8 ‘(F1,78=5.700, P
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Kirstin Daalman, Sanne Verkooijen, Eske M. Derks, André Aleman, Iris E.C. Sommer Tags: Erratum Source Type: research
Deficits in implicit facial recognition of fear in aggressive patients with schizophrenia
Aggression in individuals with schizophrenia is a complex, multidimensional problem (). An area of research that may hold promise for better understanding the underlying causes of aggression in schizophrenia is facial emotion recognition, which is impaired in schizophrenia patients () and related to functional outcomes ().
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Daniel Antonius, Brian Kline, Samuel Justin Sinclair, Mandi White-Ajmani, Sara Gianfagna, Dolores Malaspina, Fabien Trémeau Tags: Letters to the Editor Source Type: research
Sleep-disordered breathing in schizophrenia: An audit
Obstructive Sleep Apnea–Hypopnea Syndrome (OSAHS) is a potential disabling condition characterised by snoring, nocturnal hypoxemia and disrupted sleep. Few studies have examined OSAHS rates in schizophrenia. The aims of this study were to identify the frequency of OSAHS risk in psychiatric inpatients using audit data, and examine the demographic and clinical correlates of OSAHS.
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Flavie Waters, Katrin Hanken, Daniel Rock Tags: Letters to the Editor Source Type: research
Protein–protein interaction analysis reveals common molecular processes/pathways that contribute to risk of schizophrenia
Schizophrenia is a severe mental disorder that affects about 1% of the world's population. Though genetic studies have identified many schizophrenia susceptibility (SZ) genes, the interaction (network) among these identified genes in the etiology of schizophrenia remains poorly understood.
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Xiong-jian Luo, Liang Huang, Ming Li, Lin Gan Tags: Letters to the Editor Source Type: research
Relationship between auditory processing and affective prosody in schizophrenia
In this study, we explored links between different stages of auditory processing, using event-related potentials (ERPs), and affective prosody detection in schizophrenia. Thirty-six schizophrenia patients and 18 healthy control subjects received tasks of affective prosody, facial emotion identification, and tone matching, as well as two auditory oddball paradigms, one passive for mismatch negativity (MMN) and one active for P300. Patients had significantly reduced MMN and P300 amplitudes, impaired auditory and visual emotion recognition, and poorer tone matching performance, relative to healthy controls. Correlations betwe...
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Carol Jahshan, Jonathan K. Wynn, Michael F. Green Tags: Clinical Studies Source Type: research
Identification of clinically meaningful relationships among cognition, functionality, and symptoms in subjects with schizophrenia or schizoaffective disorder
Conclusion: Improved cognition was associated with beneficial changes in functional status and clinical symptoms (particularly disorganization symptoms) in subjects with schizophrenia/schizoaffective disorder. Older subjects showed less overall cognitive improvement. Improved cognitive and functional outcome is correlated with symptom improvements in RLAI-treated patients with schizophrenia.
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Gahan Pandina, Robert Bilder, Ibrahim Turkoz, Larry Alphs Tags: Cognition Source Type: research
Altered cortico-basal ganglia motor pathways reflect reduced volitional motor activity in schizophrenia
We examined 21 schizophrenia patients and 21 healthy controls using diffusion tensor imaging and actigraphy. We applied a probabilistic fibre tracking approach to investigate pathways connecting the dorsolateral prefrontal cortex (dlPFC), the rostral anterior cingulate cortex (rACC), the pre-supplementary motor area (pre-SMA), the supplementary motor area proper (SMA-proper), the primary motor cortex (M1), the caudate nucleus, the striatum, the pallidum and the thalamus. Schizophrenia patients had lower activity levels than controls. In schizophrenia we found higher probability indices forming part of a bundle of interest ...
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Tobias Bracht, Susanne Schnell, Andrea Federspiel, Nadja Razavi, Helge Horn, Werner Strik, Roland Wiest, Thomas Dierks, Thomas J. Müller, Sebastian Walther Tags: Neuroimaging Source Type: research
Functional connectivity of left Heschl's gyrus in vulnerability to auditory hallucinations in schizophrenia
Conclusions: Abnormal interactions between left Heschl's gyrus and regions involved in speech/language, memory, and the monitoring of self-generated events may contribute to AH vulnerability.
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Ann K. Shinn, Justin T. Baker, Bruce M. Cohen, Dost Öngür Tags: Neuroimaging Source Type: research
Psychiatric diagnoses among quitters versus continuing smokers 3 years after their quit day
Conclusions: Quitting smoking does not appear to negatively influence mental health in the long-term and may be protective with respect to depression and substance use diagnoses; this should encourage smokers to make quit attempts and encourage clinicians to provide cessation treatment.
Source: Drug and Alcohol Dependence - January 14, 2013 Category: Addiction Authors: Megan E. Piper, Matthew Rodock, Jessica W. Cook, Tanya R. Schlam, Michael C. Fiore, Timothy B. Baker Tags: Full Length Reports Source Type: research
The association between substance use disorders and mortality among a cohort of Veterans with posttraumatic stress disorder: Variation by age cohort and mortality type
Abstract: Background: Prior studies of Veterans have linked posttraumatic stress disorder (PTSD) with an increased risk of mortality. Other studies of Veterans have found that substance use disorders (SUDs) are associated with an excess risk of mortality among those with psychiatric disorders. It is not known whether having an SUD increases the risk of mortality among Veterans with PTSD, and whether the association differs by mortality type or varies by age cohort.Methods: A cohort of patients who received Veterans Health Administration services during fiscal year (FY) 2004 and diagnosed with PTSD (n=272,509) were followed...
Source: Drug and Alcohol Dependence - January 14, 2013 Category: Addiction Authors: Kipling M. Bohnert, Mark A. Ilgen, Craig S. Rosen, Rani A. Desai, Karen Austin, Frederic C. Blow Tags: Full Length Reports Source Type: research
Parent, sibling and peer associations with subtypes of psychiatric and substance use disorder comorbidity in offspring
Conclusions: We observed distinct subtypes of psychiatric and SUD comorbidity in adolescents and young adults. Subtypes of offspring psychopathology have varied associations with parental psychopathology, family environment, and sibling and peer behaviors.
Source: Drug and Alcohol Dependence - January 14, 2013 Category: Addiction Authors: Vivia V. McCutcheon, Jeffrey F. Scherrer, Julia D. Grant, Hong Xian, Jon Randolph Haber, Theodore Jacob, Kathleen K. Bucholz Tags: Full Length Reports Source Type: research