Psychiatry Research
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 25.
Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid
ff, P Bruins, E M Derks, R S Kahn
& R A Ophoff
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: J J LuykxS C BakkerE LentjesM NeelemanE StrengmanL MentinkJ DeYoungS de JongJ H SulE EskinK van EijkJ van SettenJ E Buizer-VoskampR M CantorA LuM van AmerongenE P A van DongenP KeijzersT KappenP BorgdorffP BruinsE M DerksR S KahnR A Ophoff Tags: cerebrospinal fluid CSMD1 genome-wide association study monoamine PDE9A SSTR1 Source Type: research
The multimodal connectivity of the hippocampal complex in auditory and visual hallucinations
homas
& R Jardri
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: A AmadA CachiaP GorwoodD PinsC DelmaireB RollandM MondinoP ThomasR Jardri Tags: hallucinations hippocampus MRI neuroplasticity schizophrenia visual Source Type: research
PTSD risk is associated with BDNF Val66Met and BDNF overexpression
Benevides
& R J Ursano
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: L ZhangD M BenedekC S FullertonR D ForstenJ A NaifehX X LiX Z HuH LiM JiaG Q XingK N BenevidesR J Ursano Source Type: research
MAOA and mechanisms of panic disorder revisited: from bench to molecular psychotherapy
ng, V Arolt, H-U Wittchen, A Hamm, T Kircher
& J Deckert
Source: Molecular Psychiatry - January 15, 2013 Category: Psychiatry Authors: A ReifJ RichterB StraubeM HöflerU LuekenA T GlosterH WeberK DomschkeL FehmA StröhleA JansenA GerlachM PykaI ReinhardtC KonradA WittmannB PfleidererG W AlpersP PauliT LangV AroltH-U WittchenA HammT KircherJ Deckert Tags: behavioral avoidance task fMRI monoamine oxidase A panic disorder promoter polymorphism therapygenetics Source Type: research
News: Libertas joins IPG
We're pleased to announce our latest new industry membership: the Independent Publishers Guild. The IPG is 51 years old and has more than 560 members around the world. We look forward to working with out IPG members and cont...
Source: Autism Insights - January 14, 2013 Category: Psychiatry Source Type: research
News: What's a Tumblr?
Tumblrs are a relatively new innovation in social media. Unlike other manifestations of social media Tumblrs focusses primarily on images. Libertas joined Tumblr relatively recently with the aim of establishing whether it was an...
Source: Autism Insights - January 14, 2013 Category: Psychiatry Source Type: research
Erratum to “The influence of semantic top-down processing in auditory verbal hallucinations” [Schizophr. Res. 139 (1–3) (2012) 82–86]
The author regrets that the following error occurred in the paper above: Page 84, right column, paragraph 3.2, line 8 ‘(F1,78=5.700, P
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Kirstin Daalman, Sanne Verkooijen, Eske M. Derks, André Aleman, Iris E.C. Sommer Tags: Erratum Source Type: research
Deficits in implicit facial recognition of fear in aggressive patients with schizophrenia
Aggression in individuals with schizophrenia is a complex, multidimensional problem (). An area of research that may hold promise for better understanding the underlying causes of aggression in schizophrenia is facial emotion recognition, which is impaired in schizophrenia patients () and related to functional outcomes ().
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Daniel Antonius, Brian Kline, Samuel Justin Sinclair, Mandi White-Ajmani, Sara Gianfagna, Dolores Malaspina, Fabien Trémeau Tags: Letters to the Editor Source Type: research
Sleep-disordered breathing in schizophrenia: An audit
Obstructive Sleep Apnea–Hypopnea Syndrome (OSAHS) is a potential disabling condition characterised by snoring, nocturnal hypoxemia and disrupted sleep. Few studies have examined OSAHS rates in schizophrenia. The aims of this study were to identify the frequency of OSAHS risk in psychiatric inpatients using audit data, and examine the demographic and clinical correlates of OSAHS.
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Flavie Waters, Katrin Hanken, Daniel Rock Tags: Letters to the Editor Source Type: research
Protein–protein interaction analysis reveals common molecular processes/pathways that contribute to risk of schizophrenia
Schizophrenia is a severe mental disorder that affects about 1% of the world's population. Though genetic studies have identified many schizophrenia susceptibility (SZ) genes, the interaction (network) among these identified genes in the etiology of schizophrenia remains poorly understood.
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Xiong-jian Luo, Liang Huang, Ming Li, Lin Gan Tags: Letters to the Editor Source Type: research
Relationship between auditory processing and affective prosody in schizophrenia
In this study, we explored links between different stages of auditory processing, using event-related potentials (ERPs), and affective prosody detection in schizophrenia. Thirty-six schizophrenia patients and 18 healthy control subjects received tasks of affective prosody, facial emotion identification, and tone matching, as well as two auditory oddball paradigms, one passive for mismatch negativity (MMN) and one active for P300. Patients had significantly reduced MMN and P300 amplitudes, impaired auditory and visual emotion recognition, and poorer tone matching performance, relative to healthy controls. Correlations betwe...
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Carol Jahshan, Jonathan K. Wynn, Michael F. Green Tags: Clinical Studies Source Type: research
Identification of clinically meaningful relationships among cognition, functionality, and symptoms in subjects with schizophrenia or schizoaffective disorder
Conclusion: Improved cognition was associated with beneficial changes in functional status and clinical symptoms (particularly disorganization symptoms) in subjects with schizophrenia/schizoaffective disorder. Older subjects showed less overall cognitive improvement. Improved cognitive and functional outcome is correlated with symptom improvements in RLAI-treated patients with schizophrenia.
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Gahan Pandina, Robert Bilder, Ibrahim Turkoz, Larry Alphs Tags: Cognition Source Type: research
Altered cortico-basal ganglia motor pathways reflect reduced volitional motor activity in schizophrenia
We examined 21 schizophrenia patients and 21 healthy controls using diffusion tensor imaging and actigraphy. We applied a probabilistic fibre tracking approach to investigate pathways connecting the dorsolateral prefrontal cortex (dlPFC), the rostral anterior cingulate cortex (rACC), the pre-supplementary motor area (pre-SMA), the supplementary motor area proper (SMA-proper), the primary motor cortex (M1), the caudate nucleus, the striatum, the pallidum and the thalamus. Schizophrenia patients had lower activity levels than controls. In schizophrenia we found higher probability indices forming part of a bundle of interest ...
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Tobias Bracht, Susanne Schnell, Andrea Federspiel, Nadja Razavi, Helge Horn, Werner Strik, Roland Wiest, Thomas Dierks, Thomas J. Müller, Sebastian Walther Tags: Neuroimaging Source Type: research
Functional connectivity of left Heschl's gyrus in vulnerability to auditory hallucinations in schizophrenia
Conclusions: Abnormal interactions between left Heschl's gyrus and regions involved in speech/language, memory, and the monitoring of self-generated events may contribute to AH vulnerability.
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Ann K. Shinn, Justin T. Baker, Bruce M. Cohen, Dost Öngür Tags: Neuroimaging Source Type: research
Editorial Board
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Source Type: research
Psychiatric diagnoses among quitters versus continuing smokers 3 years after their quit day
Conclusions: Quitting smoking does not appear to negatively influence mental health in the long-term and may be protective with respect to depression and substance use diagnoses; this should encourage smokers to make quit attempts and encourage clinicians to provide cessation treatment.
Source: Drug and Alcohol Dependence - January 14, 2013 Category: Addiction Authors: Megan E. Piper, Matthew Rodock, Jessica W. Cook, Tanya R. Schlam, Michael C. Fiore, Timothy B. Baker Tags: Full Length Reports Source Type: research
The association between substance use disorders and mortality among a cohort of Veterans with posttraumatic stress disorder: Variation by age cohort and mortality type
Abstract: Background: Prior studies of Veterans have linked posttraumatic stress disorder (PTSD) with an increased risk of mortality. Other studies of Veterans have found that substance use disorders (SUDs) are associated with an excess risk of mortality among those with psychiatric disorders. It is not known whether having an SUD increases the risk of mortality among Veterans with PTSD, and whether the association differs by mortality type or varies by age cohort.Methods: A cohort of patients who received Veterans Health Administration services during fiscal year (FY) 2004 and diagnosed with PTSD (n=272,509) were followed...
Source: Drug and Alcohol Dependence - January 14, 2013 Category: Addiction Authors: Kipling M. Bohnert, Mark A. Ilgen, Craig S. Rosen, Rani A. Desai, Karen Austin, Frederic C. Blow Tags: Full Length Reports Source Type: research
Parent, sibling and peer associations with subtypes of psychiatric and substance use disorder comorbidity in offspring
Conclusions: We observed distinct subtypes of psychiatric and SUD comorbidity in adolescents and young adults. Subtypes of offspring psychopathology have varied associations with parental psychopathology, family environment, and sibling and peer behaviors.
Source: Drug and Alcohol Dependence - January 14, 2013 Category: Addiction Authors: Vivia V. McCutcheon, Jeffrey F. Scherrer, Julia D. Grant, Hong Xian, Jon Randolph Haber, Theodore Jacob, Kathleen K. Bucholz Tags: Full Length Reports Source Type: research
Theory of Mind differences in older patients with early‐onset and late‐onset paranoid schizophrenia
ConclusionsThese results suggest that ToM functioning may be a protective factor modulating the age at onset of psychosis. Further studies into the relationship between social cognition and onset age of psychosis are warranted. Copyright © 2013 John Wiley & Sons, Ltd.
Source: International Journal of Geriatric Psychiatry - January 14, 2013 Category: Geriatrics Authors: M. M. J. Smeets‐Janssen, P. D. Meesters, H. C. Comijs, P. Eikelenboom, J. H. Smit, L. Haan, A. T. F. Beekman, M. L. Stek Tags: Research Article Source Type: research
Non-neurological and metabolic side effects in the Cost Utility of the Latest Antipsychotics in Schizophrenia Randomised Controlled Trial (CUtLASS-1)
This study provides evidence that clinicians should take a more nuanced approach toward expert antipsychotic prescription, rather than viewing the drugs as distinct classes.
Source: Schizophrenia Research - January 14, 2013 Category: Psychiatry Authors: Michael J. Peluso, Shôn W. Lewis, Thomas R.E. Barnes, Peter B. Jones Tags: Clinical Studies Source Type: research
Psychiatry's Integration with Medicine: The Role of DSM-5.
Abstract
Mental disorders represent a significant global burden whose effects are exacerbated by gaps in diagnosis and service provision. A substantial number of individuals seek services not through specialty psychiatric clinics but through primary care. Thus, the interface between psychiatry and the rest of medicine represents an appropriate area of focus in which to improve the detection and treatment of mental disorders. Development of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) can play a key role in this process. DSM-5 is expected to include specific revisions in dia...
Source: Annual Review of Medicine - January 14, 2013 Category: Journals (General) Authors: Kupfer DJ, Kuhl EA, Wulsin L Tags: Annu Rev Med Source Type: research
Validity of proposed DSM-5 diagnostic criteria for nicotine use disorder: results from 734 Israeli lifetime smokers.
CONCLUSIONS: All findings address previous concerns about the DSM-IV nicotine diagnosis and its criteria and support the proposed changes for DSM-5 NUD, which should result in improved diagnosis of nicotine disorders.
PMID: 23312475 [PubMed - as supplied by publisher]
Source: Psychological Medicine - January 14, 2013 Category: Psychiatry Authors: Shmulewitz D, Wall MM, Aharonovich E, Spivak B, Weizman A, Frisch A, Grant BF, Hasin D Tags: Psychol Med Source Type: research
Effectiveness and cost-effectiveness of body psychotherapy in the treatment of negative symptoms of schizophrenia ¿ a multi-centre randomised controlled trial
DiscussionThe study aims to evaluate the effectiveness of a promising form of group therapy which may help alleviate negative symptoms that are associated with unfavourable long-term outcomes and have so far have been difficult to treat. If the trial is successful, it will add a new and effective option in the treatment of negative symptoms. Group BPT is manualised, might be attractive to many patients because of its unusual approach, and could potentially be rolled out to services at relatively little additional cost.Trial registration: Current Controlled Trials ISRCTN84216587
Source: BMC Psychiatry - Latest articles - January 14, 2013 Category: Psychiatry Authors: Stefan PriebeMark SavillUlrich ReininghausTil WykesRichard BentallChristoph LauberPaul McCroneFrank RöhrichtSandra Eldridge Source Type: research
Effectiveness and cost-effectiveness of body psychotherapy in the treatment of negative symptoms of schizophrenia -- a multi-centre randomised controlled trial
DiscussionThe study aims to evaluate the effectiveness of a promising form of group therapy which may help alleviate negative symptoms that are associated with unfavourable long-term outcomes and have so far have been difficult to treat. If the trial is successful, it will add a new and effective option in the treatment of negative symptoms. Group BPT is manualised, might be attractive to many patients because of its unusual approach, and could potentially be rolled out to services at relatively little additional cost.Trial registration: Current Controlled Trials ISRCTN84216587
Source: BMC Psychiatry - Latest articles - January 14, 2013 Category: Psychiatry Authors: Stefan PriebeMark SavillUlrich ReininghausTil WykesRichard BentallChristoph LauberPaul McCroneFrank RöhrichtSandra Eldridge Source Type: research
Table of Contents
Abstract
Society Calls on MH Field for Answers to Preventing Mass Shootings
Tech Executive: Similar Forces Compel Vendor, Provider Deals
Ohio Executive to Take Reins at MHCA in February
NAMI Director Announces Departure at End of Year
Peer‐Based Training Helps Participants ‘Self‐Manage’ Health
State News
Names in the News
Business Notes
Coming up
Source: Mental Health Weekly - January 14, 2013 Category: Psychiatry Source Type: research
WHITE MATTER INTEGRITY AND ITS RELATIONSHIP TO PTSD AND CHILDHOOD TRAUMA—A SYSTEMATIC REVIEW AND META‐ANALYSIS
Recent reviews and meta‐analyses reported structural gray matter changes in patients suffering from adult‐onset posttraumatic stress disorder (PTSD) and in subjects with and without PTSD who experienced childhood trauma. However, it remains unclear if such structural changes are also affecting the white matter. The aim of this systematic review is to provide a comprehensive overview of all empirical investigations measuring white matter integrity in populations affected by PTSD and/or childhood trauma. To this end, results from different methodological approaches were included. Twenty‐five articles are reviewed of wh...
Source: Depression and Anxiety - January 14, 2013 Category: Psychiatry Authors: Judith K. Daniels, Jan‐Peter Lamke, Michael Gaebler, Henrik Walter, Michael Scheel Tags: Theoretical Review Source Type: research
MAJOR DEPRESSIVE DISORDER AMONG OLDER AFRICAN AMERICANS, CARIBBEAN BLACKS, AND NON‐HISPANIC WHITES: SECONDARY ANALYSIS OF THE NATIONAL SURVEY OF AMERICAN LIFE
ConclusionMDD among older adults is highly prevalent, often associated with other psychiatric disorders or chronic physical conditions, and is associated with high overall mental illness severity. Differences among older Blacks highlight the need for further research on this population to ensure appropriate treatment is being provided to these groups.
Source: Depression and Anxiety - January 14, 2013 Category: Psychiatry Authors: Amanda T. Woodward, Robert J. Taylor, Jamie M. Abelson, Niki Matusko Tags: Research Article Source Type: research
Treatment needs, diagnoses and use of services for acutely admitted psychiatric patients in northwest Russia and northern Norway
Conclusion:
Acutely admitted psychiatric patients in North West Russia and Northern Norwegian showed different clinical profiles: alcohol, depression and organic disorders characterised Russian patients, affective disorders, suicidality and use of drugs characterised the Norwegians. Whereas Norwegian patients are mainly referred from GPs the Russians come via 1.line psychiatric services ("dispensaries"). Average length of stay for Russian patients was 2.5 times longer than that of the Norwegian.
Source: BioMed Central - January 14, 2013 Category: Journals (General) Authors: Knut W SørgaardGrigory RezvyAnatoly BugdanovTore SørlieTrond Bratlid Source Type: research
Modulation of brain structure by catechol‐O‐methyltransferase Val158Met polymorphism in chronic cannabis users
Abstract
Neuroimaging studies have shown that chronic consumption of cannabis may result in alterations in brain morphology. Recent work focusing on the relationship between brain structure and the catechol‐O‐methyltransferase (COMT) gene polymorphism suggests that functional COMT variants may affect brain volume in healthy individuals and in schizophrenia patients. We measured the influence of COMT genotype on the volume of four key regions: the prefrontal cortex, neostriatum (caudate‐putamen), anterior cingulate cortex and hippocampus‐amygdala complex, in chronic early‐onset cannabis users and healthy control s...
Source: Addiction Biology - January 14, 2013 Category: Addiction Authors: Albert Batalla, Carles Soriano‐Mas, Marina López‐Solà, Marta Torrens, José A. Crippa, Sagnik Bhattacharyya, Laura Blanco‐Hinojo, Ana B. Fagundo, Ben J. Harrison, Santiago Nogué, Rafael Torre, Magí Farré, Jesús Pujol, Rocío Martín‐Santos Tags: Original Article Source Type: research
Characterization of gene-environment interactions by behavioral profiling of selectively bred rats: The effect of NMDA receptor inhibition and social isolation.
Abstract
Gene-environment interactions have an important role in the development of psychiatric disorders. To generate and validate a new substrain of rats with signs related to schizophrenia, we used selective breeding after postweaning social isolation and chronic ketamine treatment through several generations of animals and compared the subsequent strain to naive rats that were not genetically manipulated. We further investigated whether social isolation and ketamine treatment augmented the appearance of schizophrenic-like signs in these rats. Four experimental groups were studied (n=6-15 rats/group): naive rats...
Source: Behavioural Brain Research - January 13, 2013 Category: Neurology Authors: Petrovszki Z, Adam G, Tuboly G, Kekesi G, Benedek G, Keri S, Horvath G Tags: Behav Brain Res Source Type: research
Antagonizing 5-HT(2A) receptors with M100907 and stimulating 5-HT(2C) receptors with Ro60-0175 blocks cocaine-induced locomotion and zif268 mRNA expression in Sprague-Dawley rats.
Abstract
Serotonin (5-HT) plays a role in several psychiatric disorders including drug addiction. The 5-HT system modulates the activity of midbrain dopamine (DA) systems, and the behavioural effects of psychostimulants mediated by these systems. The direction of this modulation depends upon the 5-HT receptor subtypes involved, with 5-HT(2A) and 5-HT(2C) receptors having opposing effects. For example the 5-HT(2A) receptor antagonist M100907 and the 5-HT(2C) receptor agonist Ro60-0175 both attenuate several cocaine-induced behavioural and neurochemical effects. To investigate the possible brain regions involved in t...
Source: Behavioural Brain Research - January 13, 2013 Category: Neurology Authors: Burton CL, Rizos Z, Diwan M, Nobrega JN, Fletcher PJ Tags: Behav Brain Res Source Type: research
Predictors for Readmission into Children's Inpatient Mental Health Treatment.
Abstract
The goal of this study was to examine factors associated with time to first and subsequent readmissions of youth (N = 1,432) to one of Florida's residential mental health treatment programs, known as State Inpatient Psychiatric Program (SIPP). Results of multivariate Cox regression analysis indicated that greater maltreatment severity, shorter length of time spent in SIPP during the initial episode, and longer time to provision of targeted case management services were associated with earlier readmission. When time to subsequent readmission was examined, results of multivariate Cox regression analysis in...
Source: Community Mental Health Journal - January 13, 2013 Category: Psychiatry Authors: Yampolskaya S, Mowery D, Dollard N Tags: Community Ment Health J Source Type: research
Access to and Utilization of Health Services as Pathway to Racial Disparities in Serious Mental Illness.
Abstract
Often considered to fare better than White Americans in terms of mental health, African-Americans are nevertheless more vulnerable to chronic, persistent conditions should they become mentally ill, the literature suggests. The present study used data from the 2009 National Health Interview Survey to examine race differences in the prevalence rates of serious mental illness and race's role in relationships among such illness and variables of (a) social status and (b) health services. Results showed that non-Hispanic Blacks' level of reported chronic mental illness (in the past 30 days) exceeded that of non...
Source: Community Mental Health Journal - January 13, 2013 Category: Psychiatry Authors: Lo CC, Cheng TC, Howell RJ Tags: Community Ment Health J Source Type: research
Frequent Emergency Department Use Among Released Prisoners With Human Immunodeficiency Virus: Characterization Including a Novel Multimorbidity Index
ConclusionsAmong released prisoners with HIV, frequent ED use is driven primarily by extensive comorbid medical and psychiatric illness. Frequent ED users were also less likely to have received prerelease discharge planning, suggesting missed opportunities for seamless linkages to care.
Resumen
La Hiperfrecuentación al Servicio de Urgencias de los Presos Puestos en Libertad con VIH: Caracterización que Incluye un Índice de Multimorbilidad Novedoso
ObjectivosCaracterizar la correlación médica, social y psiquiátrica de la hiperfrecuentación al servicio de urgencias (SU) de los presos puestos en libertad con VIH.
M...
Source: Academic Emergency Medicine - January 13, 2013 Category: Emergency Medicine Authors: Jaimie P. Meyer, Jingjun Qiu, Nadine E. Chen, Gregory L. Larkin, Frederick L. Altice Tags: Original Research Contribution Source Type: research
Unscheduled Return Visits to the Emergency Department: Consequences for Triage
ConclusionsThe authors observed that 2% of patients had an UR. This UR population was at greater risk of AE at the time of their URs compared to their initial visits, but the median triage nurse score was not significantly different between the first visit and the UR. This suggests that the triage score should be systematically upgraded for UR patients.
Resumen
Las Reconsultas no Esperadas al Servicio de Urgencias: Consecuencias para el TriajeObjetivosRealizar un estudio de reconsultas no esperadas (RN) al servicio de urgencias (SU) en los primeros ocho días tras una primera consulta, para comprobar la hipótesis que los...
Source: Academic Emergency Medicine - January 13, 2013 Category: Emergency Medicine Authors: Gabrielle Sauvin, Yonathan Freund, Khaled Saïdi, Bruno Riou, Pierre Hausfater Tags: Original Research Contribution Source Type: research
A latent class analysis of psychological disturbance in Parkinson's disease
ConclusionsThese results support high psychological co‐morbidity in PD, which complicates the treatment of individual symptoms. In addition, emotional blunting and anhedonia may be less indicative of widespread psychological distress than anxiety, dysphoria, and cognitive aspects of apathy. Clinicians should be aware that PD patients with greater motor dysfunction and less education are at greater risk not only for depression but also for a variety of other psychological symptoms that may not be routinely assessed. Copyright © 2013 John Wiley & Sons, Ltd.
Source: International Journal of Geriatric Psychiatry - January 12, 2013 Category: Geriatrics Authors: Laura B. Zahodne, Michael Marsiske, Dawn Bowers Tags: Research Article Source Type: research
Depression, Constraint, and the Liver: (Dis)assembling the Treatment of Emotion-Related Disorders in Chinese Medicine.
This article disassembles the articulations by means of which these different facts about constraint are constructed. It shows how ideas about constraint as a disorder caused by the penetration of external pathogens into the body were gradually transformed from the eleventh century onward into constraint as an emotion-related disorder, while treatment strategies were adjusted to match perceptions about body/self that developed among the gentry elite of southeast China in late imperial China.
PMID: 23315392 [PubMed - as supplied by publisher]
Source: Culture, Medicine and Psychiatry - January 12, 2013 Category: Psychiatry Authors: Scheid V Tags: Cult Med Psychiatry Source Type: research
Association of the 5HTR2A gene with suicidal behavior: CASE-control study and updated meta-analysis
Conclusion:
Our results showed association between the rs6313 (T102C) polymorphism and suicidal behavior in the case--control study. However, the meta-analysis showed no evidence of association. Therefore, more studies are necessary to determine conclusively an association between T102C and suicidal behavior.
Source: BMC Psychiatry - Latest articles - January 12, 2013 Category: Psychiatry Authors: Thelma González-CastroCarlos Tovilla-ZárateIsela Juárez-RojopSherezada Pool GarcíaMartha Velázquez-SánchezAlma GenisHumberto NicoliniLilia López Narváez Source Type: research
Validation of the depression anxiety stress scales (DASS) 21 as a screening instrument for depression and anxiety in a rural community-based cohort of northern Vietnamese women
Conclusions:
The total score of the 21 items of the DASS21-Vietnamese validation appears to be comprehensible and sensitive to detecting common mental disorders in women with young children in primary health care in rural northern Vietnam and therefore might also be useful to screen for these conditions in other resource-constrained settings.
Source: BMC Psychiatry - Latest articles - January 12, 2013 Category: Psychiatry Authors: Thach TranTuan TranJane Fisher Source Type: research
Chronic Lyme; diagnostic and therapeutic challenges.
Abstract
In this review, we aim to discuss the definition, clinical and laboratory features, diagnostics, and management of chronic Lyme. Chronic Lyme is a rare condition caused by long-lasting and ongoing infection with the spirochete Borrelia burgdorferi (Bb). The most common manifestations are progressive encephalitis, myelitis, acrodermatitis chronica atrophicans with or without neuropathy, and arthritis. Chronic Lyme is not considered to present with isolated subjective symptoms. Direct detection of Bb has low yield in most manifestations of chronic Lyme, while almost 100% of the cases are seropositive, that i...
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Ljøstad U, Mygland A Tags: Acta Neurol Scand Suppl Source Type: research
[Department of Error] Department of Error
Franz DN, Belousova E, Sparagana S, et al. Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial. Lancet 2013; 381: 125–32—In this Article (published online Nov 14), the affiliation for Petrus J de Vries should have read “Division of Child and Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa”, and his degree should have been “PhD”. These corrections have been made to the online version as of Jan 11, 2012, and to the printed Article.
Source: LANCET - January 11, 2013 Category: Journals (General) Authors: The Lancet Tags: Department of Error Source Type: research
Influence of gender and age on cognitive inhibition in late‐onset depression: a case‐control study
ConclusionCognitive inhibition impairment, and more specifically its attention component, was the main characteristic of depression in the studied sample of older adults, independently of gender and age of depression onset. It is essential to perform similar studies in both genders in view of future tailor‐made therapeutic modalities. Copyright © 2013 John Wiley & Sons, Ltd.
Source: International Journal of Geriatric Psychiatry - January 11, 2013 Category: Geriatrics Authors: S. Richard‐Devantoy, F. Deguigne, C. Annweiler, G. Letourneau, O. Beauchet Tags: Research Article Source Type: research
Social inequalities in new antidepressant treatment: a study at the individual and neighborhood levels
Conclusions: Our results suggest that social inequalities at the individual and neighborhood levels in new antidepressant treatment occur in access to specialty care and in treatment initiation and affect its duration. Further research is warranted to improve our understanding of their mechanisms.
Source: Annals of Epidemiology - January 11, 2013 Category: Epidemiology Authors: Aurélie Bocquier, Sébastien Cortaredona, Hélène Verdoux, Vincent Sciortino, Stève Nauleau, Pierre Verger Source Type: research
Cognitive insight as an indicator of competence to consent to treatment in schizophrenia
Abstract: The processes underlying the ability to make decisions about recommended treatments remain poorly understood in schizophrenia. The aim of this study was to explore the relationships between capacity to consent to medication and cognitive biases in 60 schizophrenia patients. Main measures included the MacArthur Competence Assessment tool for Treatment (MacCAT-T) and the Beck Cognitive Insight Scale (BCIS). After Bonferroni's correction for multiple correlations, the Self-Reflectiveness dimension of the BCIS was significantly associated with the dimension “Reasoning” of the MacCAT-T. Cognitive therapy, by enhan...
Source: Schizophrenia Research - January 11, 2013 Category: Psychiatry Authors: Stéphane Raffard, Guillaume Fond, Marie Brittner, Catherine Bortolon, Alexandra Macgregor, Jean-Phillipe Boulenger, Marie-Christine Gely-Nargeot, Delphine Capdevielle Tags: Insight Source Type: research
Impairment in instrumental activities of daily living with high cognitive demand is an early marker of mild cognitive impairment: the Sydney Memory and Ageing Study.
CONCLUSIONS: IADL are affected in individuals with MCI, and IADL with a high cognitive demand show impairment predating the diagnosis of MCI. Subtle cognitive impairment is therefore likely to be a major hidden burden in society.
PMID: 23308393 [PubMed - as supplied by publisher]
Source: Psychological Medicine - January 11, 2013 Category: Psychiatry Authors: Reppermund S, Brodaty H, Crawford JD, Kochan NA, Draper B, Slavin MJ, Trollor JN, Sachdev PS Tags: Psychol Med Source Type: research
A randomized, double-blind, placebo-controlled study of rapid-acting intramuscular olanzapine in Japanese patients for schizophrenia with acute agitation
The objective of this study was to confirm the efficacy of rapid-acting IM olanzapine 10 mg was greater than IM placebo in patients with exacerbation of schizophrenia with acute psychotic agitation by comparing changes from baseline to 2 hours after the first IM injection, as measured by the Positive and Negative Syndrome Scale-Excited Component (PANSS-EC) total score.
Methods:
We conducted a placebo-controlled, randomized, double-blind, parallel-group study in Japanese patients diagnosed with schizophrenia according to the diagnostic criteria specified in the DSM-IV-TR. Patients were randomized to 2 treatment groups: IM o...
Source: BMC Psychiatry - Latest articles - January 11, 2013 Category: Psychiatry Authors: Hideaki KatagiriShinji FujikoshiTakuya SuzukiKiyoshi FujitaNaoya SugiyamaMichihiro TakahashiJuan-Carlos Gomez Source Type: research
Low intensity vs. self-guided Internet-delivered psychotherapy for major depression: a multicenter, controlled, randomized study
DiscussionThe comparisons between low intensity and self-guided are infrequent, and also a comparative economic evaluation between them and compared with usual treatment in primary. The strength of the study is that it is a multi-centre, randomized, controlled trial of low intensity and self-guided Internet-delivered psychotherapy for depression in primary care, being the treatment completely integrated in primary care setting.Trial registration: Clinical Trials NCT01611818
Source: BMC Psychiatry - Latest articles - January 11, 2013 Category: Psychiatry Authors: Yolanda López-del-HoyoBarbara OlivanJuan Luciano-DevisFermín MayoralMiquel RocaMargalida GiliEva AndresAntoni Serrano-BlancoFrancisco CollazoRicardo ArayaRosa BañosCristina BotellaRosa MagallónJavier Campayo Source Type: research
The effectiveness of individual interpersonal psychotherapy as a treatment for major depressive disorder in adult outpatients: a systematic review
Conclusions:
The differences between treatment effects are very small and often they are not significant. Psychotherapeutic treatments such as IPT and CBT, and/or pharmacotherapy are recommended as first-line treatments for depressed adult outpatients, without favoring one of them, although the individual preferences of patients should be taken into consideration in choosing a treatment.
Source: BMC Psychiatry - Latest articles - January 11, 2013 Category: Psychiatry Authors: Madelon van HeesThomas RotterTim EllermannSilvia Evers Source Type: research
Interventions to improve executive functioning and working memory in school-aged children with AD(H)D: a randomised controlled trial and stepped-care approach
This study will contribute to this lack of information, especially information related to real classroom and academic situations. By taking into account the costs of both interventions, level of impairment and individual characteristics of the child (stepped-care approach) we will be able to address treatment more adequately for each individual in the future. Trial registration: Nederlands Trial Register NTR3415.
Source: BMC Psychiatry - Latest articles - January 11, 2013 Category: Psychiatry Authors: Marthe DonkAnne-Claire Hiemstra-BeerninkAriane Tjeenk-KalffAryan LeijRamón Lindauer Source Type: research
Proof Firm d and diagnosis-specific disability pensioning in Norway
Conclusion:
Moderate downsizing is followed by a significant increase in disability pension rates in the following four years, often with complex musculoskeletal and psychiatric diagnoses.
Source: BMC Public Health - Latest articles - January 11, 2013 Category: Consumer Health News Authors: Bjørgulf ClaussenØyvind NæssLeif ReimeAlastair Leyland Source Type: research

