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Psychiatry

This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

The Israel Diabetes and Cognitive Decline (IDCD) study: Design and baseline characteristics.
CONCLUSIONS: Tracking cognition, with face-to-face evaluations, exploiting 15 years of historical detailed computerized, easily accessible, and validated T2D-related characteristics may provide novel insights into T2D-related dementia. PMID: 25150735 [PubMed - as supplied by publisher] (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - August 26, 2014 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Improvement of facial affect recognition in children and adolescents with attention-deficit/hyperactivity disorder under methylphenidate.
Discussion The collected data showed that methylphenidate leads to amelioration of facial affect recognition abilities, but not on a significant level. Reasons for missing significance may be the small sample size or the fact that there exists some overlapping in cerebral connections and metabolic pathways of the site of action of methylphenidate and the affected dopaminergic areas in ADHD. However, consistent with the endophenotype concept, certain gene locations of the dopaminergic metabolism as both an aetiological factor for ADHD and the deficient facial affect recognition abilities with these individuals were consider...
Source: Acta Neuropsychiatrica - August 22, 2014 Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research

Assessment of potential cardiovascular risks of methylphenidate in comparison with sibutramine: do we need a SCOUT (trial)?
Authors: Antel J, Albayrak O, Heusch G, Banaschewski T, Hebebrand J Abstract With the recent approval of methylphenidate (MPH) for treating attention-deficit/hyperactivity disorder (ADHD) in adults, the number of patients exposed will increase tremendously. The ongoing debate on the cardiovascular safety of MPH has triggered two large retrospective cohort studies in children and adolescents as well as in young to middle-aged adults. These studies looked into serious cardiovascular events (sudden cardiac death, acute myocardial infarction and stroke) as primary endpoints and concluded that MPH was safe after a mean ...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 26, 2014 Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research

Impaired recognition of happy facial expressions in bipolar disorder.
CONCLUSIONS: Findings suggest a deficit in happy emotion recognition impacted by processing speed. Given the limited sample size, further investigation with a larger patient sample is warranted. PMID: 25142295 [PubMed - in process] (Source: Acta Neuropsychiatrica)
Source: Acta Neuropsychiatrica - August 22, 2014 Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research

The clinical use of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: A consensus paper from the Alzheimer's Biomarkers Standardization Initiative.
CONCLUSIONS: Changes in Aβ1-42, T-tau, and P-tau181P allow diagnosis of AD in its prodromal stage. Conversely, having all three biomarkers in the normal range rules out AD. Intermediate conditions require further patient follow-up. PMID: 25150736 [PubMed - as supplied by publisher] (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - August 26, 2014 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Chronic oral carbamazepine treatment elicits mood-stabilising effects in mice.
CONCLUSIONS: These results demonstrate a behaviourally effective oral and chronic regimen for carbamazepine with mood stabilising-like activity in a standard model for mania-like behaviour and two standard models for depression-like behaviour. PMID: 25142097 [PubMed - in process] (Source: Acta Neuropsychiatrica)
Source: Acta Neuropsychiatrica - August 22, 2014 Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research

Chronic high-fat diet increases acute neuroendocrine stress response independently of prenatal dexamethasone treatment in male rats.
CONCLUSION: We conclude that chronic HFD may be more important in programming of the HPA axis stress responsiveness than an adverse foetal environment and therefore potentially implies an increased risk for developing psychiatric and metabolic disease. PMID: 25142095 [PubMed - in process] (Source: Acta Neuropsychiatrica)
Source: Acta Neuropsychiatrica - August 22, 2014 Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research

Suppression of antipsychotic-induced tardive dyskinesia with aripiprazole in an elderly patient with bipolar I disorder.
CONCLUSION: Aripiprazole could be an effective drug in elderly bipolar patients with antipsychotic-induced TD while the patients are in a euthymic state. However, aripiprazole may only suppress TD rather than cure it. PMID: 25142102 [PubMed - in process] (Source: Acta Neuropsychiatrica)
Source: Acta Neuropsychiatrica - August 22, 2014 Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research

Charting the decline in spontaneous writing in Alzheimer's disease: a longitudinal study.
This study aims to document the nature and progression of the spontaneous writing impairment observed in patients with Alzheimer's disease (AD) over a 12-month period using both a cross-sectional and prospective longitudinal design. METHODS: Thirty-one minimal-moderate AD patients and 30 controls matched for age and socio-cultural background completed a simple and complex written description task at baseline. The AD patients then had follow-up assessments at 6 and 12 months. RESULTS: Cross-sectional comparisons indicated that minimal-moderate AD patients produced more semantic paraphasias, phonological paraphasias,...
Source: Acta Neuropsychiatrica - August 22, 2014 Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research

Happiness an Attainable Goal in SchizophreniaHappiness an Attainable Goal in Schizophrenia
Happiness may be an attainable goal for at least some patients with schizophrenia and is associated with positive psychosocial attributes that can be enhanced. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - August 26, 2014 Category: Psychiatry Tags: Psychiatry News Source Type: news

Change in Identity Diffusion and Psychopathology in a Specialized Inpatient Treatment for Borderline Personality Disorder.
CONCLUSIONS: After a 12-week inpatient treatment, the findings indicate significant improvements in the DST group in typical affective borderline symptomatology and in the personality structure feature of identity diffusion. This highlights the significance of a short-term specific inpatient therapy for BPD. KEY PRACTITIONER MESSAGE: A structured, disorder-specific inpatient treatment of patients diagnosed with borderline personality disorder (BPD) combined a psychodynamic transference-focused psychotherapy treatment approach (focusing on pathological features in personality organization, particularly on non-integrated...
Source: Clinical Psychology and Psychotherapy - August 26, 2014 Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research

Meanings of manic episodes in patients with bipolar disorder in remission: a qualitative study
Conclusion The findings of this research contribute to a greater understanding of manic frames in BD that can assist in the reflections on the doctor-patient relationship, to develop strategies for adherence and the therapeutic and preventive measures of recurrent. Can assist the health team involved in monitoring these cases and also the researchers in investigation of the contribution of these meanings discussed here in the phenomena of adherence to treatment and a better prognosis. (Source: Jornal Brasileiro de Psiquiatria)
Source: Jornal Brasileiro de Psiquiatria - August 9, 2014 Category: Psychiatry Source Type: research

Disturbed cortico-amygdalar functional connectivity as pathophysiological correlate of working memory deficits in bipolar affective disorder.
Authors: Stegmayer K, Usher J, Trost S, Henseler I, Tost H, Rietschel M, Falkai P, Gruber O Abstract Patients suffering from bipolar affective disorder show deficits in working memory functions. In a previous functional magnetic resonance imaging study, we observed an abnormal hyperactivity of the amygdala in bipolar patients during articulatory rehearsal in verbal working memory. In the present study, we investigated the dynamic neurofunctional interactions between the right amygdala and the brain systems that underlie verbal working memory in both bipolar patients and healthy controls. In total, 18 euthymic bipol...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 15, 2014 Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research

White matter integrity and late-life depression in community-dwelling individuals: diffusion tensor imaging study using tract-based spatial statistics.
Conclusions Reduced white matter integrity is associated with late-life depression and predicts future depressive symptoms whereas a history of depression is not related to white matter changes. Disruption to white matter integrity may be a biomarker to predict late-life depression. PMID: 25147370 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - August 26, 2014 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Association between the NOTCH4 gene rs3131296 polymorphism with schizophrenia risk in the Chinese Zhuang population and Chinese Han population.
CONCLUSIONS: Our study failed to replicate the significant association between the NOTCH4 gene rs3131296 polymorphism and the risk for SZ. PMID: 25142293 [PubMed - in process] (Source: Acta Neuropsychiatrica)
Source: Acta Neuropsychiatrica - August 22, 2014 Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research

Emotional perception and theory of mind in first episode psychosis: The role of obsessive-compulsive symptomatology
The aim of the present study was to investigate the effects of comorbid obsessive-compulsive symptoms on emotional perception and theory of mind (ToM) in patients with first-episode psychosis. Participants were 65 patients with non-affective first episode psychosis (FEP) and 47 healthy controls. The patient group was divided into two subgroups, those with (FEP+; n=38) and those without obsessive-compulsive symptomatology (FEP-; n=27). Emotion perception and ToM were assessed with the Perception of Social Inference Test. (Source: Psychiatry Research)
Source: Psychiatry Research - July 31, 2014 Category: Psychiatry Authors: Evangelos Ntouros, Vasilios P. Bozikas, Christina Andreou, Dimitris Kourbetis, Grigoris Lavrentiadis, George Garyfallos Source Type: research

Psychometric properties of assessment instruments for autism spectrum disorder: a systematic review of Brazilian studies
Conclusion Considering both the psychometric aspects and the copyright information, the screening instrument that currently appears to be best indicated for clinical and research use is the M-CHAT. It was also noticed that there are still no specific ASD diagnostic tools available for use in Brazil. This lack of diagnostic instruments consists in a critical situation for the improvement of clinical practice and the development of research in this area. Objetivo Revisar sistematicamente a literatura científica acerca das propriedades psicométricas de instrumentos internacionais para a avaliação do transtorno do espectro...
Source: Jornal Brasileiro de Psiquiatria - August 9, 2014 Category: Psychiatry Source Type: research

Psychometric analysis of the Melancholia Scale in trials with non-pharmacological augmentation of patients with therapy-resistant depression.
CONCLUSION: The apathia subscale is a unidimensional scale with acceptable transferability for the measurement of treatment-resistant symptoms, analogue to the psychic core subscale (HAM-D6). PMID: 25142191 [PubMed - in process] (Source: Acta Neuropsychiatrica)
Source: Acta Neuropsychiatrica - August 22, 2014 Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research

Striatal Development in Autism: Repetitive Behaviors and the Reward Circuitry
Autism spectrum disorder (ASD) is defined by two essential features—impaired social communication abilities, including deficits with social reciprocity, nonverbal communication, and establishing relationships, and the presence of restricted and repetitive behaviors and interests (RRBIs). Social deficits receive most of the attention both in science and in the popular media, but RRBIs are equally important in understanding autism. Although RRBIs are also seen in typically developing preschoolers as well as in other psychiatric disorders such as obsessive-compulsive disorder, their impairing and persisting character is a h...
Source: Biological Psychiatry - August 6, 2014 Category: Psychiatry Authors: Gregor Kohls, Benjamin E. Yerys, Robert T. Schultz Tags: Commentaries Source Type: research

DSM-5 Made Easy: The Clinician’s Guide to Diagnosis
I had just come off my first overnight shift. From 8pm to 8am, I was the go-to resident for any issues that arose on any of the three psychiatry units, along with any emergent psychiatric consults from anywhere in the hospital. A psych patient couldn’t sleep? My pager went off. Another fell while getting himself a midnight snack? It’s my pager again. A patient on surgery mentioned that he couldn’t take this anymore and just wanted to end it all? Yup, that’s me, too. Someone admitted to the ICU after throwing himself from a moving car? You get the picture. By morning, we’ll just say I was getting a little tired ...
Source: Psych Central - August 26, 2014 Category: Psychiatry Authors: Megan Riddle Tags: Book Reviews Disorders Dual Diagnosis General Professional Psychiatry Psychological Assessment Dsm 5 dsm 5 made easy dsm5 mental disorder diagnosis morrison Source Type: news