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This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective.
This report is a summary of the Association's evaluation, which was presented at the October 2014 WDC meeting. The Association believes there is sufficient evidence to support the link between several modifiable risk factors and a reduced risk for cognitive decline, and sufficient evidence to suggest that some modifiable risk factors may be associated with reduced risk of dementia. Specifically, the Association believes there is sufficiently strong evidence, from a population-based perspective, to conclude that regular physical activity and management of cardiovascular risk factors (diabetes, obesity, smoking, and hyperten...
Source: The Journal of Alzheimers Association - June 7, 2015 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Relationships between mixed features and borderline personality disorder in 2811 patients with major depressive episode
ConclusionMajor depressive episode patients with comorbid BPD reported a high prevalence of mixed features and BD. The presence of DSM‐5 mixed features in MDE patients with BPD may be associated with complex course and reduced treatment response. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - June 12, 2015 Category: Psychiatry Authors: G. Perugi, J. Angst, J.‐M. Azorin, C. L. Bowden, A. Caciagli, S. Mosolov, E. Vieta, A. H. Young, Tags: Original Article Source Type: research

Correction: Postprandial oxytocin secretion is associated with severity of anxiety and depressive symptoms in anorexia nervosa.
Authors: Lawson EA Abstract [This corrects the article DOI: 10.4088/JCP.12m08154.]. PMID: 26035205 [PubMed - in process] (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - June 5, 2015 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

Long-term use of benzodiazepines and related drugs among community-dwelling individuals with and without Alzheimer’s disease
In this study, 24 966 individuals with AD and 24 985 individuals without AD were included. During the 4-year follow-up, we found that 45% (N=11 312) of individuals with AD and 38% (N=9534) of individuals without AD used BZDRs. The prevalence of long-term (≥180 days) BZDR use was more common among individuals with AD (30%) than individuals without AD (26%). The median durations of the first long-term use periods of BZDRs were 1.5 and 2 years for individuals with and without AD, respectively. Factors associated with long-term BZDR use included female sex, AD, schizophrenia, bipolar disorder, depression, coronary arte...
Source: International Clinical Psychopharmacology - June 5, 2015 Category: Psychiatry Tags: Original Articles Source Type: research

Management of Adverse Effects of Mood Stabilizers
Abstract Mood stabilizers such as lithium and anticonvulsants are still standard-of-care for the acute and long-term treatment of bipolar disorder (BD). This systematic review aimed to assess the prevalence of their adverse effects (AEs) and to provide recommendations on their clinical management. We performed a systematic research for studies reporting the prevalence of AEs with lithium, valproate, lamotrigine, and carbamazepine/oxcarbazepine. Management recommendations were then developed. Mood stabilizers have different tolerability profiles and are eventually associated to cognitive, dermatological, endocrine...
Source: Current Psychiatry Reports - June 18, 2015 Category: Psychiatry Source Type: research

Sleep duration, cognitive decline, and dementia risk in older women.
CONCLUSIONS: In older women, habitual sleep duration predicts the future risk for cognitive impairments including dementia, independent of vascular risk factors. PMID: 26086180 [PubMed - as supplied by publisher] (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - June 20, 2015 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Autism Spectrum Disorder and Amplified Pain.
Conclusion. Pain in autism can be atypical in its experience and expression and for this reason may go unrecognised by physicians treating chronic pain disorders. PMID: 26064754 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - June 14, 2015 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

CACNA1C risk variant is associated with increased amygdala volume.
Authors: Lancaster TM, Foley S, Tansey KE, Linden DE, Caseras X Abstract Genome-wide association studies suggest that genetic variation within L-type calcium channel subunits confer risk to psychosis. The single nucleotide polymorphism at rs1006737 in CACNA1C has been associated with both schizophrenia and bipolar disorder and with several intermediate phenotypes that may serve as neurobiological antecedents, linking psychosis to genetic aetiology. Amongst others, it has been implicated in alterations in amygdala structure and function. In the present study, we show that the risk allele (A) is associated with incre...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 7, 2015 Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research

Sensorimotor Psychotherapy: Interventions for Trauma & Attachment
Many of my clients ask questions during the first session like “Why is my body so tight?” or “Why can’t I sleep at night?” People want to know why their bodies react to psychological stressors such as frustration, trauma, rejection, fear, and anxiety — why all of our bodies seem programmed to respond to these as well as environmental cues, facial expressions, attitudes, and other stimuli. Pat Ogden, founder and director of the Sensorimotor Psychotherapy Institute, and Janina Fisher, a clinical psychologist specializing in trauma, synthesize psychological and medical models to explain why we physically re...
Source: Psych Central - July 2, 2015 Category: Psychiatry Authors: Tamara Hill, MS Tags: Abuse Book Reviews Disorders Family General Professional Psychological Assessment Psychotherapy Stress Treatment Interventions for Trauma Janina Fisher Pat Ogden Sensorimotor Psychotherapy Source Type: news

Bulimia Nervosa Treated With an Adapted Version of Carroll's Cognitive-Behavioral Approach for Treatment of Cocaine Addiction.
Authors: Cosci F PMID: 26037878 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Lithium Linked to Renal, Endocrine FunctionLithium Linked to Renal, Endocrine Function
Lithium, the cornerstone treatment for bipolar disorder, has been linked to renal, thyroid, and parathyroid dysfunction. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - June 10, 2015 Category: Psychiatry Tags: Psychiatry News Source Type: news

Hyperactivity and impaired attention in Gamma aminobutyric acid transporter subtype 1 gene knockout mice.
CONCLUSION: Our results demonstrated that GAT-1-/- mice have phenotypes of hyperactivity, impaired sustained attention and learning deficiency, and the performance of GAT-1-/- mice is similar to ADHD symptoms. So, the study of the GAT-1-/- mice may provide new insights into the mechanisms and the discovery of novel therapeutics for the treatment of ADHD. PMID: 26072958 [PubMed - as supplied by publisher] (Source: Acta Neuropsychiatrica)
Source: Acta Neuropsychiatrica - June 17, 2015 Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research

'I-Patients' and Smartphone Addiction: The Anesthesiology News Report
(MedPage Today) -- Also: the billion-dollar hit to healthcare from cyber attacks (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - June 18, 2015 Category: Psychiatry Source Type: news

Comparison of venlafaxine alone versus venlafaxine plus bright light therapy combination for severe major depressive disorder.
CONCLUSIONS: Both venlafaxine and venlafaxine + bright light therapy treatment strategies significantly reversed the depressive mood of patients with severe MDD; however, the latter induced significantly stronger and more rapid beneficial effects. Future longer-term studies with large sample sizes, nonetheless, are required to confirm and generalize these results to patients of diverse ethnicities and cultures with both severe and mild MDD. TRIAL REGISTRATION: ANZCTR.org.au registration number: ACTRN12614001061628. PMID: 26035199 [PubMed - in process] (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - June 5, 2015 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

[The Relationship of Suicide Attempts with Affective Temperament and Relevant Clinical Features in Patients with Mood Disorders].
CONCLUSION: The findings are expected to guadiance to preventing suicide in patients with affective disorders. The inclusion in this study of patients with different index episodes of illness, including manic, depressive and mixed periods, can be accepted as a significant limitation of this study. PMID: 26111285 [PubMed - in process] (Source: Turkish Journal of Psychiatry)
Source: Turkish Journal of Psychiatry - June 27, 2015 Category: Psychiatry Authors: Ekşioğlu S, Güleç H, Şimşek G, Semiz ÜB Tags: Turk Psikiyatri Derg Source Type: research

Armodafinil in binge eating disorder: a randomized, placebo-controlled trial
This study evaluated the efficacy, tolerability, and safety of armodafinil in the treatment of binge eating disorder (BED). Sixty participants with BED were randomized to receive armodafinil (150–250 mg/day) (N=30) or placebo (N=30) in a 10-week, prospective, parallel-group, double-blind, flexible-dose, single-center trial. In the primary longitudinal analysis, armodafinil and placebo produced similar rates of improvement in binge eating day frequency (the primary outcome measure); however, armodafinil was associated with a statistically significantly higher rate of decrease in binge eating episode frequency. In the se...
Source: International Clinical Psychopharmacology - June 5, 2015 Category: Psychiatry Tags: Original Articles Source Type: research

Modeling predictors of changes in glycemic control and diabetes-specific quality of life amongst adults with type 1 diabetes 1 year after structured education in flexible, intensive insulin therapy
Abstract Few studies have identified determinants of glycemic control (HbA1c) and diabetes-specific quality of life (DSQoL) in adults with type 1 diabetes. To identify factors predicting outcomes following structured diabetes education. 262 participants completed biomedical and questionnaire assessments before, and throughout 1 year of follow-up. The proportion of variance explained ranged from 28 to 62 % (DSQoLS) and 14–20 % (HbA1c). When change in psychosocial variables were examined, reduced hypoglycemia fear, lower ‘perceived diabetes seriousness’, greater self-efficacy and well-being predicted QoL im...
Source: Journal of Behavioral Medicine - June 14, 2015 Category: Psychiatry Source Type: research

Reliability and Validity of Proposed DSM-5 ADHD Symptoms in a Clinical Sample of Adults.
Authors: Matte B, Rohde LA, Turner JB, Fisher PW, Shen S, Bau CH, Nigg JT, Grevet EH Abstract The DSM-5 ADHD and Disruptive Behaviors Work Group proposed two major changes for diagnosis of attention deficit hyperactivity disorder (ADHD) in adults: 1) inclusion of four new impulsivity symptoms and 2) reduction in the number of symptoms required for assigning an ADHD diagnosis. In this case-control study, the performance of these modifications was assessed in a clinical sample of 133 adult subjects (68 ADHD cases and 65 non-ADHD control subjects). The proposed new impulsivity symptoms for adults do not improve ADHD d...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 14, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Abdominal obesity is associated with impaired cognitive function in euthymic bipolar individuals
The World Journal of Biological Psychiatry, Ahead of Print. (Source: World Journal of Biological Psychiatry)
Source: World Journal of Biological Psychiatry - June 13, 2015 Category: Psychiatry Tags: article Source Type: research

Reliability and validity of ADHD diagnostic criteria in the Assessment System for Individuals with ADHD (ASIA): a Japanese semi-structured diagnostic interview
Conclusions: ASIA ADHD criteria showed acceptable psychometric properties, although further investigation is necessary. The use of ASIA ADHD criteria could facilitate clinical practice and research into adult ADHD in Japan. (Source: BMC Psychiatry)
Source: BMC Psychiatry - June 20, 2015 Category: Psychiatry Authors: Toshinobu TakedaYui TsujiTeruhisa UwatokoHiroshi Kurita Source Type: research