Consensus on infertility treatment related to polycystic ovary syndrome
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(Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: The Thessaloniki ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group Tags: ERRATUM Source Type: journals
Reply: ethical recruitment of patients for pgs trial
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(Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Ankum, W. M., Reitsma, J. B., Offringa, M. Tags: LETTERS TO THE EDITOR Source Type: journals
Ethical recruitment of patients for pgs trial
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(Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Zosmer, A., Epstein, M., Al-Shawaf, T. Tags: LETTERS TO THE EDITOR Source Type: journals
Genetic polymorphisms of esr1 and esr2 that may influence estrogen activity and the risk of hypospadias
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CONCLUSIONS
These findings suggest that the G allele containing variants of ESR1 XbaI and the G allele containing variants of ESR2 2681-4A>G may decrease the risk of hypospadias, whereas the ESR1 C-A haplotype may increase its risk. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Ban, S., Sata, F., Kurahashi, N., Kasai, S., Moriya, K., Kakizaki, H., Nonomura, K., Kishi, R. Tags: Reproductive Genetics Source Type: journals
Parathyroid hormone-responsive b1 gene is associated with premature ovarian failure
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CONCLUSIONS
We showed for the first time that PTHB1 is strongly associated with POF, and ht1 confers susceptibility to POF. While causative SNPs were not identified, the polymorphism of the non-synonymous SNP rs11773504 and the repeated association of ht1 with POF suggest that PTHB1 may contribute to POF pathogenesis. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Kang, H., Lee, S. K., Kim, M.-H., Song, J., Bae, S. J., Kim, N. K., Lee, S.-H., Kwack, K. Tags: Reproductive Genetics Source Type: journals
A distinct cohort of the tgf{beta} superfamily members expressed in human endometrium regulate decidualization
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CONCLUSIONS
Like activin, BMP2 and TGFβ1 are likely to be involved in HESC decidualization. This is the first study to identify and localize BMP4, BMP7, GDF5, GDF8 and GDF11 in secretory phase human endometrium. Understanding the factors critical for the implantation process is needed for improving fertility and pregnancy outcomes. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Stoikos, C. J., Harrison, C. A., Salamonsen, L. A., Dimitriadis, E. Tags: Reproductive Genetics Source Type: journals
Greek hyperinsulinemic women, with or without polycystic ovary syndrome, display altered inositols metabolism
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CONCLUSIONS
Greek women, with or without PCOS, display increased uClDCI and decreased AUCDCI-IPG in association with higher insulin levels but independent of adiposity. Increased clearance of inositols might reduce tissue availability of DCI and decrease the release of DCI-IPG mediator, which could contribute to insulin resistance and compensatory hyperinsulinemia in Greek women, as previously described in American women. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Baillargeon, J.-P., Nestler, J. E., Ostlund, R. E., Apridonidze, T., Diamanti-Kandarakis, E. Tags: Reproductive Endocrinology Source Type: journals
Cardiovascular risks and metabolic syndrome in hong kong chinese women with polycystic ovary syndrome
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CONCLUSIONS
There is high prevalence of MetS in Hong Kong Chinese women with PCOS despite their relatively young age. Recognition of these cardiometabolic risk factors requires a high level of awareness in conjunction with early and regular screening. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Cheung, L.P., Ma, R.C.W., Lam, P.M., Lok, I.H., Haines, C.J., So, W.Y., Tong, P.C.Y., Cockram, C.S., Chow, C.C., Goggins, W.B. Tags: Reproductive Endocrinology Source Type: journals
Predicting the fsh threshold dose in women with who group ii anovulatory infertility failing to ovulate or conceive on clomiphene citrate
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CONCLUSIONS
The individual FSH threshold dose for ovulation induction in anovulatory women can be predicted based on three variables easily determined in clinical practice: menstrual cycle history, mean ovarian volume and BMI. A FSH dosage nomogram was constructed based on these parameters. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Nyboe Andersen, A., Balen, A., Platteau, P., Devroey, P., Helmgaard, L., Arce, J.-C., for the Bravelle Ovulation Induction (BOI) Study Group Tags: Reproductive Endocrinology Source Type: journals
The endocrine and follicular growth dynamics throughout the menstrual cycle in women with consistently or variably elevated early follicular phase fsh compared with controls
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CONCLUSIONS
The endocrine cycle profile in younger subfertile patients with consistently elevated basal FSH resembles that in published data from older women and also reflects a low ovarian reserve. Normalization of FSH in association with normal inhibin B suggests a temporary increase of the available cohort. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: de Koning, C.H., McDonnell, J., Themmen, A.P.N., de Jong, F.H., Homburg, R., Lambalk, C.B. Tags: Reproductive Endocrinology Source Type: journals
Hypoxia is responsible for soluble vascular endothelial growth factor receptor-1 (vegfr-1) but not for soluble endoglin induction in villous trophoblast
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CONCLUSIONS
Our results support the hypotheses that, in pre-eclampsia, (i) overproduction of VEGF family factors by pre-eclamptic placenta is a consequence of induced hypoxia; (ii) overproduction of sVEGFR-1 by hypoxic villous trophoblast accounts for maternal free VEGF depletion; (iii) low circulating level of free PlGF is not only related to sVEGFR-1 overproduction, but also to hypoxia-induced mRNA down-regulation; (iv) Eng is not modulated by hypoxia. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Munaut, C., Lorquet, S., Pequeux, C., Blacher, S., Berndt, S., Frankenne, F., Foidart, J.-M. Tags: Reproductive Biology Source Type: journals
Myeloid ecotropic viral integration site 1 (meis) 1 involvement in embryonic implantation
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CONCLUSIONS
The results suggest that in mouse, meis1 contributes to regulating endometrial development during the menstrual cycle and establishing the conditions necessary for implantation. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Xu, B., Geerts, D., Qian, K., Zhang, H., Zhu, G. Tags: Reproductive Biology Source Type: journals
Native human zona pellucida glycoproteins: purification and binding properties
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CONCLUSIONS
This manuscript describes the biological activities of purified hZP glycoproteins from the native source for the first time. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Chiu, P. C.N., Wong, B. S.T., Lee, C.L., Pang, R. T.K., Lee, K.-F., Sumitro, S.B., Gupta, S.K., Yeung, W. S.B. Tags: Embryology Source Type: journals
Contribution of the oocyte nucleus and cytoplasm to the determination of meiotic and developmental competence in mice
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CONCLUSIONS
The differences in meiotic and developmental competence between SN and NSN oocytes are determined by factors in the cytoplasm and nucleus, respectively. In addition, material(s) within SN-type GVs, and not the chromatin configuration itself, is essential for full-term development. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Inoue, A., Nakajima, R., Nagata, M., Aoki, F. Tags: Embryology Source Type: journals
Changing etiology of tubal pregnancy following ivf
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CONCLUSIONS
E-cadherin can serve as a marker of implantation. Differential expression of this adhesion molecule in TP post-IVF, when compared with natural conception, may reflect a different mechanism of embryo implantation. Moreover, the observation that E-cadherin is mostly expressed in trophoblasts, and not in the tubal wall, suggests that the preimplantation embryo may actively participate in locating a suitable implantation site. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Revel, A., Ophir, I., Koler, M., Achache, H., Prus, D. Tags: Infertility Source Type: journals
Risk factors associated with pregnancies containing a monochorionic pair following assisted reproductive technologies
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CONCLUSIONS
ICSI and Day 5 embryo transfer synergistically increase the risk of monochorionic placentation. Patients undergoing these procedures should be counselled regarding these increased risks. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Skiadas, C. C., Missmer, S. A., Benson, C. B., Gee, R. E., Racowsky, C. Tags: Infertility Source Type: journals
Relevance of anti-mullerian hormone measurement in a routine ivf program
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CONCLUSIONS
AMH is a predictor of ovarian response and suitable for screening. Levels ≤1.26 ng/ml are highly predictive of reduced ovarian reserve and should be confirmed by a second line antral follicle count. Measurement of AMH supports clinical decisions, but alone it is not a suitable predictor of IVF success. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Gnoth, C., Schuring, A.N., Friol, K., Tigges, J., Mallmann, P., Godehardt, E. Tags: Infertility Source Type: journals
Flexible gnrh antagonist versus flare-up gnrh agonist protocol in poor responders treated by ivf: a randomized controlled trial
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CONCLUSIONS
The flexible GnRH antagonist protocol is associated with significantly higher ongoing pregnancy rates compared with the flare-up GnRH agonist protocol in poor responders (www.clinicaltrials.gov; NCT00417066). (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Lainas, T. G., Sfontouris, I. A., Papanikolaou, E. G., Zorzovilis, J. Z., Petsas, G. K., Lainas, G. T., Kolibianakis, E. M. Tags: Infertility Source Type: journals
Estrogen addition to progesterone for luteal phase support in cycles stimulated with gnrh analogues and gonadotrophins for ivf: a systematic review and meta-analysis
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CONCLUSIONS
The currently available evidence suggests that the addition of estrogen to progesterone for luteal phase support does not increase the probability of pregnancy in IVF. However, there is an obvious need for further RCTs that will assess, with more confidence, the effect of estrogen addition to progesterone during the luteal phase on the probability of pregnancy. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Kolibianakis, E.M., Venetis, C.A., Papanikolaou, E.G., Diedrich, K., Tarlatzis, B.C., Griesinger, G. Tags: Infertility Source Type: journals
The cost-effectiveness of long-acting reversible contraceptive methods in the uk: analysis based on a decision-analytic model developed for a national institute for health and clinical excellence (nice) clinical practice guideline
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CONCLUSIONS
LARC methods are cost-effective from the British NHS perspective. Practices improving user satisfaction and continuation of LARC method use should be identified and promoted. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Mavranezouli, I., on behalf of the LARC Guideline Development Group Tags: Fertility Control Source Type: journals
Isolation of human single chain variable fragment antibodies against specific sperm antigens for immunocontraceptive development
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CONCLUSIONS
This is the first study to report the use of phage display technology to obtain antisperm scFv antibodies of defined antigen specificity. These antibodies will find clinical applications in the development of novel immunocontraceptives, and specific diagnostics for immunoinfertility. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Samuel, A.S., Naz, R.K. Tags: Fertility Control Source Type: journals
Induced abortions previous to ivf: an epidemiologic register-based study from finland
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CONCLUSIONS
At different points in their life, women may rely on opposite fertility regulation strategies. Health care professionals providing IVF need to consider the possibility of a previous abortion. Young women need information on the possibility of future infertility in later age. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Hemminki, E., Klemetti, R., Sevon, T., Gissler, M. Tags: Reproductive Epidemiology Source Type: journals
The impact of a decline in fecundity and of pregnancy postponement on final number of children and demand for assisted reproduction technology
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CONCLUSION
A relatively important decrease in fecundability and an increase by 2.5 years in age at first pregnancy attempt are likely to have only a limited impact on fertility. However, they may have a large impact on the proportion of involuntarily infertile couples, likely to resort to assisted reproduction techniques. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Leridon, H., Slama, R. Tags: Reproductive Epidemiology Source Type: journals
Congenital anomalies in twins: a register-based study
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CONCLUSIONS
This study using high quality, population-based data on multiple pregnancies and congenital anomalies found that twins, particularly MC twins, have a higher risk of congenital anomalies than singletons. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Glinianaia, S.V., Rankin, J., Wright, C. Tags: Reproductive Epidemiology Source Type: journals
Admission to hospital of singleton children born following assisted reproductive technology (art)
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CONCLUSIONS
Couples undertaking ART should be aware that ART infants are more likely to be admitted to a NICU, to be hospitalized in the first year of life and to stay in hospital longer than other children. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Hansen, M., Colvin, L., Petterson, B., Kurinczuk, J. J., de Klerk, N., Bower, C. Tags: Reproductive Epidemiology Source Type: journals
Paternal age and adverse birth outcomes: teenager or 40+, who is at risk?
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CONCLUSIONS
Teenage fathers carry an increased risk of adverse birth outcomes that is independent of maternal confounders, whereas advanced paternal age is not an independent risk factor for adverse birth outcomes. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Chen, X.-K., Wen, S. W., Krewski, D., Fleming, N., Yang, Q., Walker, M. C. Tags: Reproductive Epidemiology Source Type: journals
Restricted expression of the human daz protein in premeiotic germ cells
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CONCLUSIONS
The expression of DAZ proteins in adult human testes is restricted to the spermatogonia and suggests a premeiotic role. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Huang, W. J., Lin, Y.-W., Hsiao, K.-N., Eilber, K. S., Salido, E. C., Yen, P. H. Tags: Andrology Source Type: journals
Fas receptor is not present on ejaculated human sperm
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CONCLUSIONS
There is no detectable quantity of Fas on human ejaculated sperm. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Perticarari, S., Ricci, G., Boscolo, R., De Santis, M., Pagnini, G., Martinelli, M., Presani, G. Tags: Andrology Source Type: journals
Nuclear organization in human sperm: preliminary evidence for altered sex chromosome centromere position in infertile males
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CONCLUSIONS
Our findings cast doubt on the reliability of centromeric probes for aneuploidy screening. The analysis of chromosome position in sperm heads should be further investigated for the screening of infertile men. (Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Finch, K.A., Fonseka, K.G.L., Abogrein, A., Ioannou, D., Handyside, A.H., Thornhill, A.R., Hickson, N., Griffin, D.K. Tags: Andrology Source Type: journals
Revised guidelines for good practice in ivf laboratories
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The ‘ESHRE Guidelines for Good Practice in IVF Laboratories’ were drawn up by the Special Interest Group (SIG) in Embryology and published in the year 2000, and since then they constitute the minimal requirements for any laboratory offering assisted reproduction techniques (ART). In the understanding that the embryologist has a responsibility for the correct and justified application of ART in the laboratory, the implementation of these guidelines requires a quality management programme to be in place that encompasses and integrates the operative units, the processes and procedures that represent the core of AR...
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Magli, M. C., Van den Abbeel, E., Lundin, K., Royere, D., Van der Elst, J., Gianaroli, L., for Committee of the Special Interest Group on Embryology Tags: ESHRE PAGES Source Type: journals
Cell identity in the preimplantation mammalian embryo: an epigenetic perspective from the mouse
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The early preimplantation mouse embryo is a unique system where it is possible to explore the foundations of totipotency and differentiation. Following fertilization, a single cell, the zygote, will give rise to all tissues of the organism. The first signs of differentiation in the embryo are evident at the blastocyst stage with the formation of the trophectoderm, a differentiated tissue that envelopes the inner cell mass. The question of when and how the cells start to be different from each other in the embryo is central to developmental biology: as cell fate decisions are undertaken, loss of totipotency comes about. Alt...
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Torres-Padilla, M. E. Tags: DEVELOPMENTS IN REPRODUCTIVE BIOLOGY AND MEDICINE Source Type: journals
Coming soon to your clinic: high-quality art
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The concept of ‘patient-friendly’ medically assisted reproduction includes a robust set of clinical practice principles, to improve the quality of subfertility care. This concept is an important move away from the sole focus on effectiveness and high pregnancy rates in assisted reproduction technology (ART). Although the concept of ‘patient-friendly ART’ has several strong points, we feel it is incomplete. For achieving true high-quality ART, the concept should be extended to two more dimensions: timeliness and patient centredness. Moreover, we propose a change in the concept's name to the less ambi...
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: van Empel, I. W.H., Nelen, W. L.D.M., Hermens, R. P.M.G., Kremer, J. A.M. Tags: DEBATE-CONTINUED Source Type: journals
The human sperm proteome: the potential for new biomarkers of male fertility and a transformation in our understanding of the spermatozoon as a machine: commentary on the article 'identification of proteomic differences in asthenozoospermic sperm samples' by martinez et al.
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(Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Barratt, C. L.R. Tags: Commentary Source Type: journals
Editor's choice
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(Source: Human Reproduction)
Source: Human Reproduction - May 16, 2008 Category: Reproduction Medicine Authors: Van Steirteghem, A. Tags: EDITORIAL Source Type: journals
Parental origin of chromatin in human monopronuclear zygotes revealed by asymmetric histone methylation patterns, differs between ivf and icsi
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In mouse zygotes, many post-translational histone modifications are asymmetrically present in male and female pronuclei. We investigated whether this principle could be used to determine the genetic composition of monopronuclear human zygotes in conventional IVF and ICSI. First we determined whether male female asymmetry is conserved from mouse to human by staining polypronuclear zygotes with antibodies against a subset of histone N-tail post-translational modifications. To analyze human monopronuclear zygotes, a modification, H3K9me3, was selected that is present in the maternal chromatin. After IVF a total of 45 monopron...
Source: Molecular Reproduction and Development - May 16, 2008 Category: Reproduction Medicine Authors: G.W. van der Heijden, I.M. van den Berg, E.B. Baart, A.A.H.A. Derijck, E. Martini, P. de Boer Source Type: journals
Selective er{alpha} activation disrupts sex organ differentiation and induces expression of vitellogenin ii and very low-density apolipoprotein ii in japanese quail embryos.
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Selective ER{alpha} activation disrupts sex organ differentiation and induces expression of vitellogenin II and very low-density apolipoprotein II in Japanese quail embryos.
Reproduction. 2008 May 15;
Authors: Mattsson A, Olsson J, Brunström B
The Japanese quail (Coturnix japonica) is a widely-used model species for studying the roles of steroid hormones in avian sex differentiation. The aim of the present study was to elucidate the significance of estrogen receptors alpha and beta (ERalpha and ERbeta) in normal sex differentiation of the reproductive organs in the Japanese quail and in xenoestrogen-induce...
Source: Reproduction - May 15, 2008 Category: Reproduction Medicine Authors: Mattsson A, Olsson J, Brunström B Tags: Reproduction Source Type: journals
Acrosomal status and mitochondrial activity of human spermatozoa vitrified with sucrose.
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In conclusion, vitrification of human spermatozoa with non-permeable cryoprotectants such as human serum albumin and sucrose can effectively cryopreserve the cells without significant loss of important physiological parameters.
PMID: 18483075 [PubMed - as supplied by publisher] (Source: Reproduction)
Source: Reproduction - May 15, 2008 Category: Reproduction Medicine Authors: Isachenko E, Isachenko V, Weiss J, Kreienberg R, Katkov I, Schulz M, Lulat A, Risopatrón J, Sanchez R Tags: Reproduction Source Type: journals
Nucleolar re-activation is delayed in mouse embryos cloned from two different cell lines
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In conclusion, despite normal onset of EGA in cloned embryos, activation of functional nucleoli was one cell cycle delayed in NT embryos. NT-MEF embryos displayed normal targeting but delayed activation of nucleolar proteins. Contrary, in NT-HM1 embryos, both of these processes were delayed. Mol. Reprod. Dev. © 2008 Wiley-Liss, Inc. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - May 10, 2008 Category: Reproduction Medicine Authors: O. Svarcova, A. Dinnyes, Z. Polgar, S. Bodo, M. Adorjan, Q. Meng, P. Maddox-Hyttel Source Type: journals
Functional characterization and expression analysis of the androgen receptor in zebrafish (danio rerio) testis.
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Functional characterization and expression analysis of the androgen receptor in zebrafish (Danio rerio) testis.
Reproduction. 2008 May 9;
Authors: de Waal P, Wang D, Nijenhuis W, Schulz R, Bogerd J
The biological activity of androgens, important for male sexual differentiation and development, is mediated by the androgen receptor that binds to specific DNA recognition sites regulating the transcription of androgen target genes. We investigated androgen production by adult zebrafish testis tissue, and identified 11beta-hydroxyandrostenedione, 11-ketoandrostenedione and 11-ketotestosterone as main products, and h...
Source: Reproduction - May 9, 2008 Category: Reproduction Medicine Authors: de Waal P, Wang D, Nijenhuis W, Schulz R, Bogerd J Tags: Reproduction Source Type: journals
Spatio-temporal expression pattern of progranulin in embryo implantation and placenta formation suggests a role in cell proliferation, remodelling and angiogenesis.
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This study demonstrates that high levels of progranulin expression correspond to active cell proliferation, remodelling and angiogenesis occurring during the establishment of the placenta in the mink.
PMID: 18469036 [PubMed - as supplied by publisher] (Source: Reproduction)
Source: Reproduction - May 9, 2008 Category: Reproduction Medicine Authors: Desmarais J, Cao M, Bateman A, Murphy B Tags: Reproduction Source Type: journals
Short term maternal psychological stress in the post-conception period in ewes affects fetal growth and gestation length.
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This study investigated the effect of maternal feed intake and psychological stress within the first 6 days after conception, on embryo development and fetal growth. Superovulated ewes (n=40) were artificially inseminated with semen from one ram. Ewes were then divided into four groups (n=10). Group 1, (Control), was fed at maintenance level, group 2 (High) at 2 x maintenance and group 3 (Low) at 0.5 x maintenance on Days 2-6 after conception. Group 4 (Stress) was fed at maintenance level and then an intense physical and psychological stress challenge was applied for 1 hour only on Days 2 and 3 after conception. Embryos we...
Source: Reproduction - May 9, 2008 Category: Reproduction Medicine Authors: Hill J, Smith J, Ferguson D, Jauregui G, Panarace M, Medina M, Lehnert S Tags: Reproduction Source Type: journals
He6/gpr64 adhesion receptor co-localizes with apical and subapical f-actin scaffold in male excurrent duct epithelia.
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HE6/GPR64 adhesion receptor co-localizes with apical and subapical F-actin scaffold in male excurrent duct epithelia.
Reproduction. 2008 May 9;
Authors: Kirchhoff C, Samalecos A, Osterhoff C
A role for HE6/Gpr64 in male excurrent ducts in the regulation of water balance was suggested from targeted gene mutation in the mouse. Results of the present immunolocalization study strengthen this hypothesis. Employing monospecific antibodies and laser confocal microscopy we studied the localization of the receptor protein in the human and wild-type mouse ductuli efferentes and epididymis. We show that HE6/Gpr64 is speci...
Source: Reproduction - May 9, 2008 Category: Reproduction Medicine Authors: Kirchhoff C, Samalecos A, Osterhoff C Tags: Reproduction Source Type: journals
Follicular development in european ground squirrels (spermophilus citellus) in different phases of the annual cycle.
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This study investigates follicular development in European ground squirrels (Spermophilus citellus) in three phases of the annual cycle: at vernal emergence, after weaning the offspring and shortly before hibernation. The animals were kept in outdoor enclosures within the natural habitat of the species. They were captured in weekly intervals, weighed and reproductive status was determined. Unilateral ovariectomy was scheduled such that the three periods were sampled. Numbers and diameters of tertiary follicles and corpora lutea in each ovary were determined, and plasma oestradiol and progesterone levels were analysed. The ...
Source: Reproduction - May 9, 2008 Category: Reproduction Medicine Authors: Millesi E, Strauss A, Burger T, Hoffmann I, Walzl M Tags: Reproduction Source Type: journals
Expression of growth differentiation factor 9 (gdf-9), bone morphogenetic protein 15 (bmp-15) and anti-mullerian hormone (amh) in cultured mouse primary follicles.
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The objectives of this study were: 1) to compare ovarian follicular populations between organ-cultured neonatal mouse ovaries and freshly isolated age-matched control ovaries; 2) to quantify RNA levels of GDF-9, BMP-15 and AMH, in cultured primary follicles; and 3) to immunolocalize GDF-9 and AMH in cultured ovaries. Ovaries from 3-day-old (PND 3) mice were cultured for 7 or 10 days in absence or presence of FSH. Follicular populations were counted in freshly isolated 13-day-old (PND 13) ovaries and organ-cultured ovaries. Transcripts were quantified in isolated primary follicles using real-time RT-PCR, and protein express...
Source: Reproduction - May 9, 2008 Category: Reproduction Medicine Authors: Sadeu JC, Adriaenssens T, Smitz J Tags: Reproduction Source Type: journals
{beta}-microseminoprotein in human spermatozoa and its potential role in male fertility.
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The objectives of this study were: (1) to purify MSMB from seminal plasma (SP) and generate antibodies against the pure protein; (2) to investigate the interaction of MSMB with ejaculated spermatozoa and its possible effect on the spontaneous acrosome reaction (AR) and (3) to quantify MSMB content in seminal plasma and examine its relationship with the clinical sperm parameters. MSMB was purified from SP and its presence on the sperm surface was examined by indirect immunofluorescence using a specific polyclonal antibody. The effect of MSMB on the AR was evaluated using guinea pig epididymal spermatozoa as model. MSMB quan...
Source: Reproduction - May 9, 2008 Category: Reproduction Medicine Authors: Franchi N, Avendaño C, Molina R, Tissera A, Maldonado C, Oehninger S, Coronel C Tags: Reproduction Source Type: journals
Locally elevated leukemia inhibitory factor in the inflamed fallopian tube resembles that found in tubal pregnancy.
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CONCLUSION(S): Leukemia inhibitory factor might be one of the reasons that cause patients with salpingitis to be more susceptible to tubal pregnancy and might be involved in the implantation process of tubal pregnancy.
PMID: 18468598 [PubMed - as supplied by publisher] (Source: Fertility and Sterility)
Source: Fertility and Sterility - May 9, 2008 Category: Reproduction Medicine Authors: Ji YF, Chen LY, Xu KH, Yao JF, Shi YF Tags: Fertil Steril Source Type: journals
Mechanism of severe ovarian hyperstimulation syndrome.
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PMID: 18468599 [PubMed - as supplied by publisher] (Source: Fertility and Sterility)
Source: Fertility and Sterility - May 9, 2008 Category: Reproduction Medicine Authors: Manno M, Tomei F Tags: Fertil Steril Source Type: journals
Role of human albumin in ovarian hyperstimulation syndrome.
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PMID: 18468600 [PubMed - as supplied by publisher] (Source: Fertility and Sterility)
Source: Fertility and Sterility - May 9, 2008 Category: Reproduction Medicine Authors: Cohen BM Tags: Fertil Steril Source Type: journals
Sensory nerve endings and endometriotic implants.
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PMID: 18468601 [PubMed - as supplied by publisher] (Source: Fertility and Sterility)
Source: Fertility and Sterility - May 9, 2008 Category: Reproduction Medicine Authors: Fraser IS, Tokushige N, Markham R, Russell P Tags: Fertil Steril Source Type: journals
Mechanisms of severe ohss.
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Mechanisms of Severe OHSS.
Fertil Steril. 2008 May 9;
Authors: Ata B, Yakin K, Alatas C, Urman B
PMID: 18468602 [PubMed - as supplied by publisher] (Source: Fertility and Sterility)
Source: Fertility and Sterility - May 9, 2008 Category: Reproduction Medicine Authors: Ata B, Yakin K, Alatas C, Urman B Tags: Fertil Steril Source Type: journals
