Respiratory Medicine
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This page shows you the most recent publications within this specialty of the MedWorm directory.
81659 records returned
Cimicifuga foetida L. Inhibited Human Respiratory Syncytial Virus in HEp-2 and A549 Cell Lines.
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Abstract
Human respiratory syncytial virus (HRSV) causes serious pediatric infection of the lower respiratory tract without effective therapeutic modality. Sheng-Ma-Ge-Gen-Tang (SMGGT; Shoma-kakkon-to) has been proven to be effective at inhibiting HRSV-induced plaque formation, and Cimicifuga foetida is the major constituent of SMGGT. We tested the hypothesis that C. foetida effectively inhibited the cytopathic effects of HRSV by a plaque reduction assay in both human upper (HEp2) and lower (A549) respiratory tract cell lines. Its ability to stimulate anti-viral cytokines was evaluated by an enzyme-linked immunosor...
Source: The American Journal of Chinese Medicine - February 5, 2012 Category: Complementary Medicine Authors: Wang KC, Chang JS, Chiang LC, Lin CC Tags: Am J Chin Med Source Type: research
Impaired phagocytosis among patients infected by the human immunodeficiency virus: implication for a role of highly active anti-retroviral therapy.
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Abstract
In patients with human immunodeficiency virus (HIV) infection, neutrophil and monocyte functions, including phagocytosis, are impaired. The purpose of this study was to investigate changes of phagocytic function and respiratory burst occurring over the course of patients infected by the HIV-1 virus. Treatment-naive patients (group B), patients receiving highly active anti-retroviral treatment (HAART) (group C) and patients in which HAART has failed (group D) were studied and compared with healthy volunteers (group A). Phagocytosis and oxidative burst were evaluated using commercially available kits. Result...
Source: Clinical and Developmental Immunology - February 5, 2012 Category: Allergy & Immunology Authors: Michailidis C, Giannopoulos G, Vigklis V, Armenis K, Tsakris A, Gargalianos P Tags: Clin Exp Immunol Source Type: research
Protumor activity of interleukin‐22 in HPAFII human pancreatic cancer cells
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In this report, we showed that IL‐22 stimulated production of vascular endothelial growth factor (VEGF) and the anti‐apoptotic factor Bcl‐XL in IL‐22R‐positive HPAFII human pancreatic cancer cells. Additionally, IL‐22 augmented HPAFII cell production of immunosuppressive cytokines. We further showed that IL‐22 activation of HPAFII cells diminished T cell production of IFN‐γ through the action of IL‐10. Strikingly, we showed for the first time that IL‐22 can fully protect cancer cells from NK cell‐mediated cytotoxicity by stimulating tumor production of IL‐10 and TGF‐β1. Our data supports the ide...
Source: Clinical and Experimental Immunology - February 5, 2012 Category: Allergy & Immunology Authors: L. M. CurdS. E. FavorsR. K. Gregg Source Type: research
Autophagic proteins: New facets of the oxygen paradox.
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Abstract
Oxygen (O 2), while essential for aerobic life, can also cause metabolic toxicity through the excess generation of reactive oxygen species (ROS). Pathological changes in ROS production can originate through the partial reduction of O 2 during mitochondrial electron transport, as well as from enzymatic sources. This phenomenon, termed the oxygen paradox, has been implicated in aging and disease, and is especially evident in critical care medicine. Whereas high O 2 concentrations are utilized as a life-sustaining therapeutic for respiratory insufficiency, they in turn can cause acute lung injury. Alveolar ep...
Source: Autophagy - February 5, 2012 Category: Cytology Authors: Jin Y, Tanaka A, Choi AM, Ryter SW Tags: Autophagy Source Type: research
Changes in lung tumor shape during respiration.
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Abstract
Evidence that some lung tumors change shape during respiration is derived from respiratory gated CT data by statistical shape modeling and image manipulation. Some tumors behave as rigid objects while others show systematic shape changes. Two views of lung motion are presented to allow analysis of the results. In the first, lung motion is viewed as a wave motion in which inertial effects arising from mass are present and in the second it is a quasistatic motion in which the mass of the lung tissues is neglected. In the first scenario, the extremes of tumor compression and expansion are expected to correlat...
Source: Physics in Medicine and Biology - February 3, 2012 Category: Physics Authors: Kyriakou E, McKenzie DR Tags: Phys Med Biol Source Type: research
Role of leptin as antioxidant in obstructive sleep apnea: an in vitro study using electron paramagnetic resonance method
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Conclusion Leptin is an antioxidant agent of possible use as a marker of OS and future risk of atherosclerotic disease in OSA.
Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s11325-012-0656-8Authors
Madalina Macrea, Salem VA Medical Center, affiliate of the University of Virginia School of Medicine, Charlottesville, VA, USAThomas Martin, Salem VA Medical Center, affiliate of the University of Virginia School of Medicine, Charlottesville, VA, USALeon Zagrean, Physiology Department, “Carol Davila” School of Medicine, Bucharest, RomaniaZhenquan Jia, Department of Biology, Uni...
Source: Sleep and Breathing - February 3, 2012 Category: Respiratory Medicine Tags: Sleep and Breathing Source Type: research
Mixed approach encourages physical activity in asthma patients
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A multicomponent protocol can lead to clinically significant increases in physical activity among patients with asthma, US researchers report. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - February 3, 2012 Category: Respiratory Medicine Source Type: news
Oral voriconazole versus intravenous low dose amphotericin B for primary antifungal prophylaxis in pediatric acute leukemia induction: a prospective, randomized, clinical study
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Mandhaniya S, Swaroop C, Thulkar S, Vishnubhatla S, Kabra SK, Xess I, Bakhshi S (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 3, 2012 Category: Respiratory Medicine Source Type: news
Aspergillus myosin-V supports polarized growth in the absence of microtubule-based transport
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Zhang J, Tan K, Wu X, Chen G, Sun J, Reck-Peterson SL, Hammer JA 3rd, Xiang X (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 3, 2012 Category: Respiratory Medicine Source Type: news
Low Interleukin-17A Production in Response to Fungal Pathogens in Patients with Chronic Granulomatous Disease
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Smeekens SP, Henriet SS, Gresnigt MS, Joosten LA, Hermans PW, Netea MG, Warris A, van de Veerdonk FL (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 3, 2012 Category: Respiratory Medicine Source Type: news
Intracranial Aspergillus granuloma
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Sundaram C, Murthy JM (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 3, 2012 Category: Respiratory Medicine Source Type: news
Response to: Lack of intra-laboratory reproducibility in using Platelia Aspergillus enzyme immunoassay test for detection of Aspergillus galactomannan antigen
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Bizzini A, Marchetti O, Meylan P (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 3, 2012 Category: Respiratory Medicine Source Type: news
Indole alkaloids from marine-derived fungus Aspergillus sydowii SCSIO 00305
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He F, Sun YL, Liu KS, Zhang XY, Qian PY, Wang YF, Qi SH (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 3, 2012 Category: Respiratory Medicine Source Type: news
Recovery of aerobic and anaerobic bacteria in sinus fungal ball
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Brook I (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 3, 2012 Category: Respiratory Medicine Source Type: news
A case–control study of craniofacial features of children with obstructed sleep apnea
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Conclusions The case group differed from the control group in the length of mandible, anterior lower facial height, position of hyoid
and the chin, and the size of the As and T/Ps.
Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s11325-011-0636-4Authors
Jinrong Deng, 3rd dental centre, School and Hospital of Stomatology, Peking University, Beijing, ChinaXuemei Gao, Department of Orthodontics, School and Hospital of Stomatology, Peking University, 22 Zhongguancun Nandajie, Haidian District, Beijing 100181, China
Journal Sleep and BreathingOnline ISSN 1522-1709Print ISS...
Source: Sleep and Breathing - February 3, 2012 Category: Respiratory Medicine Tags: Sleep and Breathing Source Type: research
Too Few American Adults Getting Needed Vaccinations: CDC
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Title: Too Few American Adults Getting Needed Vaccinations: CDCCategory: Health NewsCreated: 2/2/2012 4:06:00 PMLast Editorial Review: 2/3/2012 (Source: MedicineNet Asthma General)
Source: MedicineNet Asthma General - February 3, 2012 Category: Respiratory Medicine Source Type: news
clarithromycin, Biaxin, Biaxin XL
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Title: clarithromycin, Biaxin, Biaxin XLCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 2/3/2012 (Source: MedicineNet Asthma General)
Source: MedicineNet Asthma General - February 3, 2012 Category: Respiratory Medicine Source Type: news
Leukoencephalopathies in Mitochondrial Disorders: Clinical and MRI Findings
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ABSTRACTThe second most frequently affected organ in mitochondrial disorders (MIDs) is the central nervous system (CNS). One of the most frequent CNS abnormalities on imaging is the affection of the white matter (WMLs) for which the term, leukoencephalopathies in mitochondrial disorders (LEM), is proposed. The morphology of LEM on imaging is quite variable even within the same type of MID and the same family. LEM can be a subtle or prominent feature on imaging and may go along with or without clinical neurologic or neuropsychological manifestations. WMLs are most likely due to the underlying metabolic defect of the respira...
Source: Journal of Neuroimaging - February 3, 2012 Category: Radiology Authors: Josef FinstererSinda Zarrouk Mahjoub Tags: Views and Reviews Source Type: research
Disproportionate body composition and perinatal outcome in large‐for‐gestational‐age infants to mothers with type 1 diabetes
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Conclusions High birthweight, irrespective of body proportionality, is a risk factor for neonatal complications in offspring of women with type 1 diabetes. (Source: BJOG: An International Journal of Obstetrics and Gynaecology)
Source: BJOG: An International Journal of Obstetrics and Gynaecology - February 3, 2012 Category: OBGYN Authors: M PerssonD PasupathyU HansonM Norman Source Type: research
Growth Hormone Response Induced by a Respiratory Muscle Endurance Training in Healthy Subjects
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Horm Metab ResDOI: 10.1055/s-0031-1301303To date, the large majority of studies evaluating growth hormone (GH) response to acute physical exercise has been performed involving gross muscle groups. To the best of our knowledge, none has evaluated the effects of a respiratory muscle endurance training (RMET) on hormonal secretions, particularly on GH release, though some respiratory devices have been widely used in athletes to train respiratory muscles and to improve cardiopulmonary function and physical performance. 8 healthy men underwent an incremental progressive RMET protocol of 11 daily sessions, obtained through the u...
Source: Hormone and Metabolic Research - February 3, 2012 Category: Endocrinology Authors: Sartorio, A.Agosti, F.Patrizi, A.Compri, E.Muller, E. E.Cella, S. G.Rigamonti, A. E. Tags: Humans, Clinical Source Type: research
Coughing and other respiratory symptoms improve within weeks of smoking cessation
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(Mary Ann Liebert, Inc./Genetic Engineering News) A new study shows that 18- to 24-year olds who stop smoking for at least two weeks report substantially fewer respiratory symptoms, especially coughing. The study appears in the peer-reviewed journal Pediatric Allergy, Immunology, and Pulmonology. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 3, 2012 Category: Global & Universal Source Type: news
Health utility after emergency medical admission: A cross-sectional survey
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Conclusions:
Health utility can be measured after emergency medical admission, although responder bias may be significant. Health utility after emergency medical admission is poor compared to population norms. We have identified independent predictors or health utility that need to be measured and taken into account in non-randomized evaluations of emergency care. (Source: Health and Quality of Life Outcomes)
Source: Health and Quality of Life Outcomes - February 3, 2012 Category: Global & Universal Authors: Steve GoodacreRichard WilsonMike BradburnMartina SantarelliJon Nicholl Source Type: research
Comparison of Pandemic and Seasonal Influenza A InfectionsComparison of Pandemic and Seasonal Influenza A Infections
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This study compares the clinical and epidemiological features. Influenza and Other Respiratory Viruses (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 2, 2012 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news
Countering health threats by chemicals with a potential terrorist background - creating a rapid alert system for Europe.
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CONCLUSION: The RAS-CHEM database works and will be integrated into the Health Emergency Operations Facility (HEOF) with other European Rapid Alert Systems. Poisons centres receive a large number of enquiries and could be important sentinels in this field of toxicovigilance.
PMID: 22284259 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - February 2, 2012 Category: Internal Medicine Authors: Schaper A, Desel H, Wyke S, Orford R, Griffiths MR, Edwards N, Kupferschmidt H, Mathieu M, Pelclova D, Duarte-Davidson R Tags: Eur J Intern Med Source Type: research
Thoracic Ultrasound Demonstrates Variable Location of the Intercostal Artery
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Respiration (DOI:10.1159/000330920) (Source: Respiration)
Source: Respiration - February 2, 2012 Category: Respiratory Medicine Source Type: research
IL-6 and IL-13 in Induced Sputum of COPD and Asthma Patients: Correlation with Respiratory Tests
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Respiration (DOI:10.1159/000334900) (Source: Respiration)
Source: Respiration - February 2, 2012 Category: Respiratory Medicine Source Type: research
A Computer Model for the Simulation of Nonspherical Particle Dynamics in the Human Respiratory Tract
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In the study presented here deposition of spheres and nonspherical particles with various aspect ratios (0.01–100) in the human respiratory tract was theoretically modeled. Shape of the nonspherical particles was considered by the application of the latest aerodynamic diameter concepts. Particle deposition was predicted by using a stochastic model of the lung geometry and simulating particle transport trajectories according to the random-walk algorithm. Concerning fibers total deposition is significantly enhanced with respect to that of spheres for μm-sized particles, whereby at normal breathing conditions per...
Source: Advances in Pharmacological Sciences - February 2, 2012 Category: Drugs & Pharmacology Source Type: research
Anesthetic Management of Direct Laryngoscopy and Dilatation of Subglottic Stenosis in a Patient with Severe Myasthenia Gravis
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We describe the anesthetic management of a patient with severe myasthenia gravis and tracheal stenosis; the patient was scheduled for direct laryngoscopy and dilatation. The combination of myasthenia gravis and tracheal obstruction presents several difficulties for anesthetic management. The airway is shared; therefore, any complications are also shared by the anesthesiologist and bronchoscopists. The potential for respiratory compromise in patients undergoing the two procedures requires that anesthesiologists be familiar with the underlying disease state, as well as the interaction of anesthetic and nonanesthetic drugs in...
Source: Advances in Pharmacological Sciences - February 2, 2012 Category: Drugs & Pharmacology Source Type: research
Obstructive pressure peak: a new method for differentiation of obstructive and central apneas under auto-CPAP therapy
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Conclusions The analysis of the pressure characteristics of APAP treatment with the registration of OPP allows a further differentiation
in obstructed and not obstructed upper airways.
Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s11325-012-0657-7Authors
K. H. Ruhle, Department of Pneumology, HELIOS Clinic Ambrock, Ambrockerweg 60, 58091 Hagen, GermanyU. Domanski, Department of Pneumology, HELIOS Clinic Ambrock, Ambrockerweg 60, 58091 Hagen, GermanyG. Nilius, Department of Pneumology, HELIOS Clinic Ambrock, Ambrockerweg 60, 58091 Hagen, Germany
Journal Sleep and Br...
Source: Sleep and Breathing - February 2, 2012 Category: Respiratory Medicine Tags: Sleep and Breathing Source Type: research
RSV hospitalisation and healthcare utilisation in moderately prematurely born infants
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In conclusion, RSV hospitalisation in moderately prematurely born infants is associated
with increased health-related cost of care. Nevertheless, if RSV prophylaxis is to be cost-effective, a high risk group of
moderately prematurely born infants needs to be identified.
Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00431-012-1673-0Authors
Deena Shefali-Patel, Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre for Allergic Mechanisms of Asthma, King’s College London, London, UKMireia Alcazar Paris, Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre for Allerg...
Source: European Journal of Pediatrics - February 2, 2012 Category: Pediatrics Tags: European Journal of Pediatrics Source Type: research
Acute Treatment Options for Spinal Cord Injury
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Opinion statement Most treatment options for acute traumatic spinal cord injury (SCI) are directed at minimizing progression of the initial
injury and preventing secondary injury. Failure to adhere to certain guiding principles can be detrimental to the long-term
neurologic and functional outcome of these patients. Therapy for the hyperacute phase of traumatic SCI focuses on stabilizing
vital signs and follows the Advanced Trauma Life Support (ATLS) algorithm for ensuring stability of airway, breathing and
circulation, and disability (neurologic evaluation)—with spinal stabilization—and exposure. Spinal ...
Source: Current Treatment Options in Neurology - February 2, 2012 Category: Neurology Tags: Current Treatment Options in Neurology Source Type: research
The Size 1 ProSeal™ laryngeal mask airway in infants: a randomized, noncrossover study with the Classic™ laryngeal mask airway
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Conclusions: We conclude that the size 1 PLMA is a stable, safe, and efficacious airway control device during neonatal and infant anesthesia, allowing higher peak airway pressure during positive pressure ventilation, with fewer mask displacements and gastric insufflations than the cLMA. (Source: Pediatric Anesthesia)
Source: Pediatric Anesthesia - February 2, 2012 Category: Anesthesiology Authors: Maite López‐GilIgnacio MantillaTeresa BlancoEnrique TeigellMónica HerviasRosa Fernández‐López Tags: ORIGINAL ARTICLE Source Type: research
Acid-Base Disorders in Patients with Chronic Obstructive Pulmonary Disease: A Pathophysiological Review
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The authors describe the pathophysiological mechanisms leading to development of acidosis in patients with chronic obstructive pulmonary disease and its deleterious effects on outcome and mortality rate. Renal compensatory adjustments consequent to acidosis are also described in detail with emphasis on differences between acute and chronic respiratory acidosis. Mixed acid-base disturbances due to comorbidity and side effects of some drugs in these patients are also examined, and practical considerations for a correct diagnosis are provided. (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 2, 2012 Category: Allergy & Immunology Source Type: research
Lipid-Laden Alveolar Macrophages and pH Monitoring in Gastroesophageal Reflux-Related Respiratory Symptoms
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This study was conducted to prove a correlation between the detection of alimentary pulmonary fat phagocytosis and an increasing amount of proximal gastroesophageal reflux. It was assumed that proximal gastroesophageal reflux better correlates with aspiration than distal GER. Patients from 6 months to 16 years with unexplained recurrent wheezy bronchitis and bronchial hyperreactivity, or recurrent pneumonia with chronic cough underwent 24-hour double-channel pH monitoring and bronchoscopy with bronchoalveolar lavage (BAL). Aspiration of gastric content was determined by counting lipid laden alveolar macrophages from BAL sp...
Source: Clinical and Developmental Immunology - February 2, 2012 Category: Allergy & Immunology Source Type: research
Impaired phagocytosis among patients infected by the human immunodeficiency virus: implication for a role of highly active anti‐retroviral therapy
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SummaryIn patients with human immunodeficiency virus (HIV) infection, neutrophil and monocyte functions, including phagocytosis, are impaired. The purpose of this study was to investigate changes of phagocytic function and respiratory burst occurring over the course of patients infected by the HIV‐1 virus. Treatment‐naive patients (group B), patients receiving highly active anti‐retroviral treatment (HAART) (group C) and patients in which HAART has failed (group D) were studied and compared with healthy volunteers (group A). Phagocytosis and oxidative burst were evaluated using commercially available kits. Results cl...
Source: Clinical and Experimental Immunology - February 2, 2012 Category: Allergy & Immunology Authors: C. MichailidisG. GiannopoulosV. VigklisK. ArmenisA. TsakrisP. Gargalianos Source Type: research
sulfamethoxazole and trimethoprim, Bactrim, Septra
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Title: sulfamethoxazole and trimethoprim, Bactrim, SeptraCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 2/2/2012 (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - February 2, 2012 Category: Respiratory Medicine Source Type: news
Cough and dyspnoea may discriminate allergic and infectious respiratory phenotypes in infancy
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To cite this article: Rancière F, Clarisse B, Nikasinovic L, Just J, Momas I. Cough and dyspnoea may discriminate allergic and infectious respiratory phenotypes in infancy. Pediatr Allergy Immunol 2012: doi: 10.1111/j.1399‐3038.2011.01257.x.AbstractAsthma symptoms are non‐specific during infancy, making the identification of different subgroups among preschool children with early respiratory manifestations an important challenge. We previously used a clustering approach to identify bronchial obstructive phenotypes in 1‐yr‐old infants from the Pollution and Asthma Risk: an Infant Study (PARIS) birth cohort. In the ...
Source: Pediatric Allergy and Immunology - February 2, 2012 Category: Allergy & Immunology Authors: Fanny RancièreBénédicte ClarisseLydia NikasinovicJocelyne JustIsabelle Momas Tags: ORIGINAL ARTICLE Source Type: research
Obstructive pressure peak: a new method for differentiation of obstructive and central apneas under auto-CPAP therapy.
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CONCLUSIONS: The analysis of the pressure characteristics of APAP treatment with the registration of OPP allows a further differentiation in obstructed and not obstructed upper airways.
PMID: 22302201 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - February 2, 2012 Category: Sleep Medicine Authors: Ruhle KH, Domanski U, Nilius G Tags: Sleep Breath Source Type: research
Lung Transplantation in Patients with Prior Cardiothoracic Surgical Procedures
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The full spectrum of prior cardiothoracic procedures in lung transplant candidates and the impact of prior procedures on outcomes after lung transplantation (LTx) remain unknown, though the impact is considered to be large. Patients transplanted at our institution from 2004 to 2009 were identified (n = 554) and divided into two groups: patients who had undergone cardiothoracic surgical (CTS) procedures prior to LTx (n = 238) and patients who had not (non‐CTS: n = 316). Our primary endpoint was survival. Secondary endpoints included allograft function and the incidence of major complications including reexploration due to...
Source: American Journal of Transplantation - February 2, 2012 Category: Transplant Surgery Authors: N. ShigemuraJ. BhamaC. J. GriesT. KawamuraM. CrespoB. JohnsonD. ZaldonisJ. PilewskiY. ToyodaC. Bermudez Source Type: research
Nasal intermittent positive pressure ventilation after surfactant treatment for respiratory distress syndrome in preterm infants
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& R F Soll (Source: Journal of Perinatology)
Source: Journal of Perinatology - February 2, 2012 Category: Perinatology & Neonatology Authors: R RamanathanK C SekarM RasmussenJ BhatiaR F Soll Tags: respiratory distress syndrome surfactant preterm bronchopulmonary dysplasia NIPPV NCPAP Source Type: research
Endurance exercise attenuates ventilator-induced diaphragm dysfunction
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Controlled mechanical ventilation (MV) is a life-saving measure for patients in respiratory failure. However, MV renders the diaphragm inactive leading to diaphragm weakness due to both atrophy and contractile dysfunction. It is now established that oxidative stress is a requirement for MV-induced diaphragmatic proteolysis, atrophy, and contractile dysfunction to occur. Given that endurance exercise can elevate diaphragmatic antioxidant capacity and the levels of the cellular stress protein heat shock protein 72 (HSP72), we hypothesized that endurance exercise training before MV would protect the diaphragm against MV-induc...
Source: Journal of Applied Physiology - February 2, 2012 Category: Physiology Authors: Smuder, A. J., Min, K., Hudson, M. B., Kavazis, A. N., Kwon, O.-S., Nelson, W. B., Powers, S. K. Tags: ARTICLES Source Type: research
Cardiac and vascular responses to thigh cuffs and respiratory maneuvers on crewmembers of the International Space Station
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Conclusions: acute application of Braslet occlusion cuffs causes lower extremity fluid sequestration and exerts commensurate measurable effects on cardiac performance in microgravity. Ultrasound techniques to measure the hemodynamic effects of thigh cuffs in combination with respiratory maneuvers may serve as an effective tool in determining the volume status of a cardiac or hemodynamically compromised patient at the "microgravity bedside." (Source: Journal of Applied Physiology)
Source: Journal of Applied Physiology - February 2, 2012 Category: Physiology Authors: Hamilton, D. R., Sargsyan, A. E., Garcia, K., Ebert, D. J., Whitson, P. A., Feiveson, A. H., Alferova, I. V., Dulchavsky, S. A., Matveev, V. P., Bogomolov, V. V., Duncan, J. M. Tags: ARTICLES Source Type: research
Tracheal occlusions evoke respiratory load compensation and neural activation in anesthetized rats
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Airway obstruction in animals leads to compensation and avoidance behavior and elicits respiratory mechanosensation. The pattern of respiratory load compensation and neural activation in response to intrinsic, transient, tracheal occlusions (ITTO) via an inflatable tracheal cuff are unknown. We hypothesized that ITTO would cause increased diaphragm activity, decreased breathing frequency, and activation of neurons within the medullary and pontine respiratory centers without changing airway compliance. Obstructions were performed for 2–3 breaths followed by a minimum of 15 unobstructed breaths with an inflatable cuff ...
Source: Journal of Applied Physiology - February 2, 2012 Category: Physiology Authors: Pate, K. M., Davenport, P. W. Tags: ARTICLES Source Type: research
Compensatory responses to upper airway obstruction in obese apneic men and women
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Defective structural and neural upper airway properties both play a pivotal role in the pathogenesis of obstructive sleep apnea. A more favorable structural upper airway property [pharyngeal critical pressure under hypotonic conditions (passive Pcrit)] has been documented for women. However, the role of sex-related modulation in compensatory responses to upper airway obstruction (UAO), independent of the passive Pcrit, remains unclear. Obese apneic men and women underwent a standard polysomnography and physiological sleep studies to determine sleep apnea severity, passive Pcrit, and compensatory airflow and respiratory tim...
Source: Journal of Applied Physiology - February 2, 2012 Category: Physiology Authors: Chin, C.-H., Kirkness, J. P., Patil, S. P., McGinley, B. M., Smith, P. L., Schwartz, A. R., Schneider, H. Tags: ARTICLES Source Type: research
Impact of repeated daily exposure to intermittent hypoxia and mild sustained hypercapnia on apnea severity
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We examined whether exposure to intermittent hypoxia (IH) during wakefulness impacted on the apnea/hypopnea index (AHI) during sleep in individuals with sleep apnea. Participants were exposed to twelve 4-min episodes of hypoxia in the presence of sustained mild hypercapnia each day for 10 days. A control group was exposed to sustained mild hypercapnia for a similar duration. The intermittent hypoxia protocol was completed in the evening on day 1 and 10 and was followed by a sleep study. During all sleep studies, the change in esophageal pressure (Pes) from the beginning to the end of an apnea and the tidal volume immediate...
Source: Journal of Applied Physiology - February 2, 2012 Category: Physiology Authors: Yokhana, S. S., Gerst, D. G., Lee, D. S., Badr, M. S., Qureshi, T., Mateika, J. H. Tags: ARTICLES Source Type: research
Predictors of flu vaccination among urban Hispanic children and adults
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Conclusions
Possible methods for increasing vaccination levels in urban Hispanic communities include improving health literacy, making low-cost vaccination available and encouraging providers to use other office visits as opportunities to mention vaccination to patients.
Registration number
This study is registered at http://ClinicalTrials.gov (NCT00448981). (Source: Journal of Epidemiology and Community Health)
Source: Journal of Epidemiology and Community Health - February 2, 2012 Category: Epidemiology Authors: Cohen, B., Ferng, Y.-h., Wong-McLoughlin, J., Jia, H., Morse, S. S., Larson, E. L. Tags: Child and infant health Source Type: research
Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study.
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Conclusions:
200mcg/day of FP was as effective as 1000mcg/day in improving symptom control, airway inflammation, lung function and AHR in adults with mild to moderate asthma in the short term. Future studies should examine potential differential effects between low and high dose combination therapy (ICS/long acting beta agonist) on inflammation and airway remodeling over longer treatment periods. (Source: Respiratory Research)
Source: Respiratory Research - February 2, 2012 Category: Respiratory Medicine Authors: Melissa BaraketBrian OliverJanette BurgessSam LimGregory KingJudith Black Source Type: research
Systemic inflammatory profile and response to anti-tumor necrosis factor therapy in chronic obstructive pulmonary disease
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Conclusions:
A robust systemic inflammatory profile was associated with COPD. This profile was generally independent of disease severity. Because anti-tumor necrosis factor-alpha did not influence systemic inflammation, how to control the underlying pathology beyond symptom suppression remains unclear.Trial Registration: ClinicalTrials.gov, No.: NCT00056264. (Source: Respiratory Research)
Source: Respiratory Research - February 2, 2012 Category: Respiratory Medicine Authors: Matthew LozaRosemary WattFrederic BaribaudElliot BarnathanStephen Rennard Source Type: research
Mandibular distraction in neonates: indications, technique, results
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Conclusion:
Mandibular Distraction Osteogenesis is a good solution in solving respiratory distress when other procedures are failed in paediatric patients with severe micrognatia. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - February 2, 2012 Category: Pediatrics Authors: Enrico SesennaAlice MagriCinzia MagnaniBruno BreviMarilena Anghinoni Source Type: research
Tracheal Colonization in Preterm Infants Supported with Nasal CPAP
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Conclusion: The trachea of premature infants supported with CPAP is at risk for bacterial colonization. Predisposing factors, mechanisms and clinical implications of these novel findings need to be studied.© 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society (Source: Pediatrics International)
Source: Pediatrics International - February 2, 2012 Category: Pediatrics Authors: Hany AlyMagda BadawyRania H. TomerakAmani A El‐KholyAbeer S. Hamed Source Type: research
