Respiratory Medicine
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Prevalences of asthma and rhinitis among adolescents in the city of Fortaleza, Brazil: temporal changes
CONCLUSIONS: Our data show that the prevalences of asthma and rhinitis symptoms remain high among females and private school students. (Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - May 15, 2013 Category: Respiratory Medicine Source Type: research
Tomographic and functional findings in severe COPD: comparison between the wood smoke-related and smoking-related disease
CONCLUSIONES: En pacientes con EPOC-L severa no hay enfisema en la TCAR. El hallazgo más importante es el compromiso severo de la vía aérea. La disminución de la DLCO y del VA con DLCO/VA normal es probablemente determinada por la obstrucción bronquial severa y la mezcla incompleta del gas inspirado en la maniobra de la respiración única de la prueba de difusión.OBJECTIVE: Wood smoke exposure is a risk factor for COPD. For a given degree of airway obstruction, the reduction in DLCO is smaller in individuals with wood smoke-related COPD than in those with smoking-related COPD, suggesting that there is less emphysema...
Source: Jornal Brasileiro de Pneumologia - May 15, 2013 Category: Respiratory Medicine Source Type: research
Materials in Some Household Products Tied to Lung Damage
Breathing in 'nanomaterials' seems to cause inflammation, study contends (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - May 15, 2013 Category: Respiratory Medicine Authors: webmaster at doctorslounge.com Tags: Family Medicine, Pulmonology, Rheumatology, Preventive Medicine, News, Source Type: news
‘Obesity paradox’ holds true in COPD
Obese patients with chronic obstructive pulmonary disease are significantly less likely to die in hospital, or to be readmitted following an exacerbation than normal weight patients, show the results of Spanish research. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 15, 2013 Category: Respiratory Medicine Source Type: news
ASCO: Immune Therapy Wins Praise
CHICAGO (MedPage Today) -- A fifth of heavily pretreated patients with advanced cancers responded to a monoclonal antibody that blocks a tumor's ability to hide from the immune system, a preliminary clinical study showed. (Source: MedPage Today Pulmonary)
Source: MedPage Today Pulmonary - May 15, 2013 Category: Respiratory Medicine Source Type: news
ASCO: Fitness at 50 Linked to Less Cancer Risk
CHICAGO (MedPage Today) -- For middle-age men, good physical fitness reduces the risk of lung and colorectal cancer, a researcher said. (Source: MedPage Today Pulmonary)
Source: MedPage Today Pulmonary - May 15, 2013 Category: Respiratory Medicine Source Type: news
COPD and Allergic Diseases
(Ivanhoe Newswire) -- Researchers at Johns Hopkins University in Baltimore have discovered that patients with chronic obstructive pulmonary disease (COPD) who also have allergic disease have higher levels of respiratory symptoms and are at higher risk for COPD exacerbations. (Source: Medical Headlines From Ivanhoe.com)
Source: Medical Headlines From Ivanhoe.com - May 15, 2013 Category: Consumer Health News Source Type: news
CT Findings of Sinonasal Respiratory Epithelial Adenomatoid Hamartoma: A Closer Look at the Olfactory Clefts [HEAD & NECK]
CONCLUSIONS:
Both clinical presentations of REAH are associated with OC widening on CT scan. In the setting of polypoid disease, an OC width of > 10 mm should increase suspicion for the presence of REAH. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - May 15, 2013 Category: Radiology Authors: Hawley, K. A., Ahmed, M., Sindwani, R. Tags: HEAD & amp; NECK Source Type: research
Airway exposure to staphylococcal enterotoxin A potentiates allergen-induced bone marrow eosinophilia and trafficking to peripheral blood and airways
Bone marrow (BM) eosinopoiesis is a common feature during allergen exposure in atopic individuals. Airway exposure to staphylococcal superantigens aggravates allergic airway disease and increases the output of BM eosinophils. However, the exact mechanisms regulating eosinophil mobilization and trafficking to the peripheral circulation and airways remain to be elucidated. Therefore, this study aimed to investigate the mechanisms determining the BM eosinopoiesis in allergic mice under exposure to staphylococcal enterotoxin A (SEA). Ovalbumin (OVA)-sensitized male BALB/C mice were intranasally exposed to SEA (1 μg), and at...
Source: AJP: Lung Cellular and Molecular Physiology - May 15, 2013 Category: Respiratory Medicine Authors: Squebola-Cola, D. M., Mello, G. C., Pissinatti, L., Schenka, A. A., Anhe, G. F., DeSouza, I. A., Condino-Neto, A., Antunes, E. Tags: CALL FOR PAPERS Source Type: research
Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo
We examined lung function by blood gas analysis, extent of lung injury, and expression of HO-1. We also investigated the role of NF-E2-related factor (Nrf) 2, which regulates HO-1 expression, by examining the expression of Nrf2-dependent genes and the ability of hydrogen to reduce hyperoxic lung injury in Nrf2-deficient mice. Hydrogen treatment during exposure to hyperoxia significantly improved blood oxygenation, reduced inflammatory events, and induced HO-1 expression. Hydrogen did not mitigate hyperoxic lung injury or induce HO-1 in Nrf2-deficient mice. These findings indicate that hydrogen gas can ameliorate hyperoxic ...
Source: AJP: Lung Cellular and Molecular Physiology - May 15, 2013 Category: Respiratory Medicine Authors: Kawamura, T., Wakabayashi, N., Shigemura, N., Huang, C.-S., Masutani, K., Tanaka, Y., Noda, K., Peng, X., Takahashi, T., Billiar, T. R., Okumura, M., Toyoda, Y., Kensler, T. W., Nakao, A. Tags: ARTICLES Source Type: research
Nociceptin/orphanin FQ receptor activation decreases the airway hyperresponsiveness induced by allergen in sensitized mice
In conclusion, we demonstrated a role for the NOP receptor and N/OFQ pathway in the AHR induced by allergen, probably through a modulation of the immune response that triggers the development of AHR that involves pro- and anti-inflammatory cytokines. (Source: AJP: Lung Cellular and Molecular Physiology)
Source: AJP: Lung Cellular and Molecular Physiology - May 15, 2013 Category: Respiratory Medicine Authors: Sullo, N., Roviezzo, F., Matteis, M., Ianaro, A., Calo, G., Guerrini, R., Gruttola, L. D., Spaziano, G., Cirino, G., Rossi, F., D'Agostino, B. Tags: ARTICLES Source Type: research
Combustion derived ultrafine particles induce cytochrome P-450 expression in specific lung compartments in the developing neonatal and adult rat
Vehicle exhaust is rich in polycyclic aromatic hydrocarbons (PAH) and can be a dominant contributor to ultrafine urban particulate matter (PM). Exposure to ultrafine PM is correlated with respiratory infections and asthmatic symptoms in young children. The lung undergoes substantial growth, alveolarization, and cellular maturation within the first years of life, which may be impacted by environmental pollutants such as PM. PAHs in PM can serve as ligands for the aryl hydrocarbon receptor (AhR) that induces expression of certain isozymes in the cytochrome P-450 superfamily, such as CYP1A1 and CYP1B1, localized in specific l...
Source: AJP: Lung Cellular and Molecular Physiology - May 15, 2013 Category: Respiratory Medicine Authors: Chan, J. K. W., Vogel, C. F., Baek, J., Kodani, S. D., Uppal, R. S., Bein, K. J., Anderson, D. S., Van Winkle, L. S. Tags: ARTICLES Source Type: research
Mineralocorticoid receptor antagonism attenuates experimental pulmonary hypertension
Mineralocorticoid receptor (MR) activation stimulates systemic vascular and left ventricular remodeling. We hypothesized that MR contributes to pulmonary vascular and right ventricular (RV) remodeling of pulmonary hypertension (PH). We evaluated the efficacy of MR antagonism by spironolactone in two experimental PH models; mouse chronic hypoxia-induced PH (prevention model) and rat monocrotaline-induced PH (prevention and treatment models). Last, the biological function of the MR was analyzed in cultured distal pulmonary artery smooth muscle cells (PASMCs). In hypoxic PH mice, spironolactone attenuated the increase in RV s...
Source: AJP: Lung Cellular and Molecular Physiology - May 15, 2013 Category: Respiratory Medicine Authors: Preston, I. R., Sagliani, K. D., Warburton, R. R., Hill, N. S., Fanburg, B. L., Jaffe, I. Z. Tags: ARTICLES Source Type: research
Mechanical induction of group V phospholipase A2 causes lung inflammation and acute lung injury
This study tested the hypothesis that onset of VILI is triggered by activation of secretory group V phospholipase A2 (gVPLA2) in pulmonary vascular endothelium exposed to excessive mechanical stretch. High-magnitude cyclic stretch (18% CS) increased expression and surface exposure of gVPLA2 in human pulmonary endothelial cells (EC). CS-induced gVPLA2 activation was required for activation of ICAM-1 expression and polymorphonuclear neutrophil (PMN) adhesion to CS-preconditioned EC. By contrast, physiological CS (5% CS) had no effect on gVPLA2 activation or EC-PMN adhesion. CS-induced ICAM-1 expression and EC-PMN adhesion we...
Source: AJP: Lung Cellular and Molecular Physiology - May 15, 2013 Category: Respiratory Medicine Authors: Meliton, A. Y., Munoz, N. M., Meliton, L. N., Birukova, A. A., Leff, A. R., Birukov, K. G. Tags: ARTICLES Source Type: research
Human neutrophil elastase-mediated goblet cell metaplasia is attenuated in TACE-deficient mice
Neutrophilic inflammation is associated with chronic airway diseases. It has been observed that human neutrophil elastase (HNE), which is secreted by active neutrophils during inflammation, induces both mucin overproduction and goblet cell metaplasia. Several in vitro studies suggest that tumor necrosis factor-α converting enzyme (TACE) regulates the signaling axis that mediates HNE-induced mucin overproduction; however, it is unknown whether TACE performs a similar function in HNE-induced goblet cell metaplasia in vivo. We conducted this study to determine whether the inactivation of Tace gene expression attenuates ...
Source: AJP: Lung Cellular and Molecular Physiology - May 15, 2013 Category: Respiratory Medicine Authors: Park, J.-A., Sharif, A. S., Shiomi, T., Kobzik, L., Kasahara, D. I., Tschumperlin, D. J., Voynow, J., Drazen, J. M. Tags: ARTICLES Source Type: research
Systemic inflammation, depression and obstructive pulmonary function: a population-based study
Conclusions:
This study found for the first time an association of depressive symptoms and pulmonary function in older adults which appeared to be partly mediated by proinflammatory cytokines. Further studies should be conducted to investigate proinflammatory immune markers and depressive symptoms as potential phenotypic indicators for chronic obstructive airway disorders in older adults. (Source: Respiratory Research)
Source: Respiratory Research - May 15, 2013 Category: Respiratory Medicine Authors: Yanxia LuLei FengLiang FengMa Shwe NyuntKeng Bee YapTze Pin Ng Source Type: research
Allergic Disease Ups Respiratory Problems in COPD PatientsAllergic Disease Ups Respiratory Problems in COPD Patients
A study of 1468 patients with COPD concluded that those who had a concomitant diagnosis of allergic disease were at increased risk of developing respiratory symptoms and flare-ups of COPD. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 14, 2013 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news
World Briefing | Middle East: Saudi Arabia: New Virus Spreads
Saudi Arabia has confirmed six new cases of the SARS-like coronavirus in its Eastern Province in recent days, the state news media reported. (Source: NYT Health)
Source: NYT Health - May 14, 2013 Category: Consumer Health News Authors: By REUTERS Tags: Saudi Arabia SARS (Severe Acute Respiratory Syndrome) Source Type: news
GOLD adherence raises costs in stage III COPD
Results of Spanish research show that adherence to the Global Initiative for Chronic Lung Disease guidelines reduces overall costs in the treatment of stage II chronic obstructive pulmonary disease, but not in stage III disease. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 14, 2013 Category: Respiratory Medicine Source Type: news
Asymptomatic Carriage Of M. Pneumoniae Common In Children
The bacterium M. pneumoniae is carried at high rates in the upper respiratory tracts of healthy children and usual diagnostic tests cannot differentiate between such asymptomatic carriage and actual respiratory tract infection, according to a study by Dutch researchers published in this week's PLOS Medicine. These findings are important as they suggest that clinicians may need to reconsider the clinical significance of a positive test result for the presence of this bacterium... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 14, 2013 Category: Consumer Health News Tags: Pediatrics / Children's Health Source Type: news
Saudi Arabia Confirms Six New Cases of Deadly SARS-Like Virus
Saudi Arabia has confirmed six new cases of the SARS-like novel coronavirus in its Eastern Province, state media reported on Monday and Tuesday, citing the health ministry.Source: Reuters Health
Related MedlinePlus Pages: International Health, Severe Acute Respiratory Syndrome (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 14, 2013 Category: Consumer Health News Source Type: news
Major Pulmonary Embolism and Patent Foramen Ovale
The thrombus is localized in the pulmonary artery and its branches in most cases of major pulmonary embolism (MPE). Rare are the cases of biatrial thrombus entrapped in a patent foramen ovale (PFO). In such circumstances, MPE may be associated with cardiogenic shock, with a high risk of mortality. Fibrinolytic agents are the main treatment of MPE, but when they are contraindicated or failed to treat MPE, or in a patient with a risk of cardiac arrest by occlusion of cardiac blood flow, a surgical pulmonary embolectomy under cardiopulmonary bypass (CPB) remains the referred treatment. The authors report the case of a 59-year...
Source: Journal of Cardiothoracic and Vascular Anesthesia - May 14, 2013 Category: Anesthesiology Authors: Julie Alingrin, Aude Carillion, Angeline Martin, Yves Saade, Jean-Marc Malinovsky Tags: Letters to the Editor Source Type: research
Intrathecal Morphine: The Forgotten Child
MOST PATIENTS EXPERIENCE considerable postoperative pain after thoracotomy. The pain originates from multiple sites and has somatic, visceral, and neurogenic components. The intensity of post-thoracotomy pain is related to the type and the extent of the surgical incision and is exacerbated during coughing. Pain after video-assisted thoracic surgery (VATS) is caused by damage to intercostal nerves that may have been crushed or severed during insertion of trocars. Respiratory function is impaired because patients tend to refrain from taking deep breaths that cause pain. Effective analgesia and inhibition of the perioperative...
Source: Journal of Cardiothoracic and Vascular Anesthesia - May 14, 2013 Category: Anesthesiology Authors: Edmond Cohen Tags: Editorial Source Type: research
Respiratory Symptoms And Exacerbations In COPD Worsened By Allergic Disease
Patients with chronic obstructive pulmonary disease (COPD) who also have allergic disease have higher levels of respiratory symptoms and are at higher risk for COPD exacerbations, according to a new study from researchers at Johns Hopkins University in Baltimore. "Although allergic sensitization and allergen exposure are known to be associated with impairments in lung function, the effects of allergic disease on respiratory symptoms in COPD patients has only recently been studied," said researcher Nadia N... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 14, 2013 Category: Consumer Health News Tags: COPD Source Type: news
Recurrent Wheeze in Healthy Preterm Infants
(Ivanhoe Newswire) – Researchers out of the University Medical Center Utrecht performed a multicenter, double-blind, randomized trial to determine the potential causal role of respiratory syncytial virus (RSV) infection in the pathogenesis of wheezing illness during the first year of life, using the commercial monoclonal antibody palivizumab against RSV. (Source: Medical Headlines From Ivanhoe.com)
Source: Medical Headlines From Ivanhoe.com - May 14, 2013 Category: Consumer Health News Source Type: news
Abdominal MR Imaging in Children: Motion Compensation, Sequence Optimization, and Protocol Organization [Pediatric Imaging]
Familiarity with basic sequence properties and their trade-offs is necessary for radiologists performing abdominal magnetic resonance (MR) imaging. Acquiring diagnostic-quality MR images in the pediatric abdomen is challenging due to motion, inability to breath hold, varying patient size, and artifacts. Motion-compensation techniques (eg, respiratory gating, signal averaging, suppression of signal from moving tissue, swapping phase- and frequency-encoding directions, use of faster sequences with breath holding, parallel imaging, and radial k-space filling) can improve image quality. Each of these techniques is more suitabl...
Source: Radiographics recent issues - May 14, 2013 Category: Radiology Authors: Chavhan, G. B., Babyn, P. S., Vasanawala, S. S. Tags: Magnetic Resonance Imaging, Pediatric Radiology, Quality Assurance/Quality Improvement, Gastrointestinal Radiology Pediatric Imaging Source Type: research
Respirology Case Reports ‐ Birth of a new online journal
(Source: Respirology)
Source: Respirology - May 14, 2013 Category: Respiratory Medicine Authors: Peter R. Eastwood Tags: Editorial Source Type: research
Respirology Case Reports – New and filling a gap
(Source: Respirology)
Source: Respirology - May 14, 2013 Category: Respiratory Medicine Authors: Norbert Berend Tags: Editorial Source Type: research
Clinical usefulness of a guideline‐based screening tool for the diagnosis of allergic rhinitis in asthmatics: the SACRA (Self Assessment of Allergic Rhinitis and Asthma) Questionnaire.
ConclusionsSACRA may be a clinically useful tool for identifying bronchial asthma patients with AR. (Source: Respirology)
Source: Respirology - May 14, 2013 Category: Respiratory Medicine Authors: Masayuki Hojo, Ken Ohta, Motoyasu Iikura, Tomonori Mizutani, Junko Hirashima, Haruhito Sugiyama Tags: Original Article Source Type: research
In Vitro Delivery of Aerosolized Treprostinil via Modern Mechanical Ventilation
Journal of Aerosol Medicine and Pulmonary Drug Delivery , Vol. 0, No. 0. (Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery)
Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery - May 13, 2013 Category: Respiratory Medicine Tags: article Source Type: research
France Confirms Second Case of Virus Linked to SARS
The cases are being watched closely because the transmission occurred in a shared hospital room. (Source: NYT Health)
Source: NYT Health - May 13, 2013 Category: Consumer Health News Authors: By STEVEN ERLANGER Tags: Infections Viruses SARS (Severe Acute Respiratory Syndrome) Deaths (Fatalities) France World Health Organization Source Type: news
COPD clinicians urged not to ignore allergies
US research shows that patients with chronic obstructive pulmonary disease who have allergic symptoms or allergic sensitization experience more symptoms and exacerbations than those who do not. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 13, 2013 Category: Respiratory Medicine Source Type: news
'SARS-like' virus infects second French patient
A second diagnosis of the new SARS-like virus coronavirus was confirmed in France on Sunday as clinicians are urged to watch for 'a-typical' respiratory symptoms in patients who have recently visited the Middle East
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Source: Nursing in Practice - May 13, 2013 Category: Nursing Authors: Lalah-Simone Springer Tags: Family health Infections Editor ' s pick Latest News Source Type: news
Influence of Exhalation Valve and Nebulizer Position on Albuterol Delivery During Noninvasive Positive Pressure Ventilation
Journal of Aerosol Medicine and Pulmonary Drug Delivery , Vol. 0, No. 0. (Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery)
Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery - May 13, 2013 Category: Respiratory Medicine Tags: article Source Type: research
Lung Deposition and Pharmacokinetics of Nebulized Cyclosporine in Lung Transplant Patients
Journal of Aerosol Medicine and Pulmonary Drug Delivery , Vol. 0, No. 0. (Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery)
Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery - May 13, 2013 Category: Respiratory Medicine Tags: article Source Type: research
Comparison of Laser Diffraction Measurements by Mastersizer X and Spraytec to Characterize Droplet Size Distribution of Medical Liquid Aerosols
Journal of Aerosol Medicine and Pulmonary Drug Delivery , Vol. 0, No. 0. (Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery)
Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery - May 13, 2013 Category: Respiratory Medicine Tags: article Source Type: research
Elan buys stake in Theravance royalties for $1 billion
Elan Corp. has made a $1 billion deal to buy a share of royalties from new drugs made by Theravance Inc., as it works to spurn a takeover offer by Royalty Pharma, Bloomberg reports.
The deal will give Elan 21 percent of royalties earned by Theravance from GlaxoSmithKline Plc on four respiratory medicines.
Elan's board last month rejected a $5.7 billion takeover bid from Royalty Pharma.
Elan said it is planning to announce several more deals this year.
Read more at Bloomberg. (Source: bizjournals.com Health Care:Hospitals headlines)
Source: bizjournals.com Health Care:Hospitals headlines - May 13, 2013 Category: Hospital Management Source Type: research
Chronic Obstructive Pulmonary Disease
Title: Chronic Obstructive Pulmonary DiseaseCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 5/13/2013 12:00:00 AM (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - May 13, 2013 Category: Respiratory Medicine Source Type: news
Breo Ellipta Approved for COPD
Title: Breo Ellipta Approved for COPDCategory: Health NewsCreated: 5/10/2013 2:36:00 PMLast Editorial Review: 5/13/2013 12:00:00 AM (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - May 13, 2013 Category: Respiratory Medicine Source Type: news
Growth characteristics of human parechovirus 1 to 6 on different cell lines and cross- neutralization of human parechovirus antibodies: a comparison of the cytopathic effect and real time PCR
Conclusion:
When replication is monitored by PCR, growth of HPeV genotypes 1 to 6 is supported by most of the cell lines tested, where viral replication is measured before appearance of CPE. A combination of HT29 and Vero cells would therefore support replication of all culturable HPeV types, so viral replication could be detected by PCR within 3 days for all genotypes.In addition, we showed efficient neutralization for HPeV1, 2, 4, 5, while cross- neutralization was shown between these types, indicating possible common neutralizing epitopes. For HPeV3 no efficient (cross-) neutralization was shown, indicating different ne...
Source: Virology Journal - May 13, 2013 Category: Virology Authors: Brenda WesterhuisSara JonkerSandhia MattaoKimberley BenschopKatja Wolthers Source Type: research
Outpatient respiratory management of the child with severe neurological impairment
Most paediatricians will have faced the challenge of managing respiratory problems in the child with severe neurological impairment. These children are under-represented in clinical trials, and data is therefore often extrapolated from other groups, for example children with cystic fibrosis. This means that robust evidence for respiratory management in children with severe neurological impairment is often lacking. Here we have attempted to piece together the existing evidence to provide a rational approach to the management of respiratory problems in children with severe neurological impairment. We also hope to highlight a...
Source: Archives of Disease in Childhood - Education and Practice - May 13, 2013 Category: Pediatrics Authors: McCrea, N., O'Donnell, R., Brown, R. Tags: Pancreas and biliary tract, Drugs: CNS (not psychiatric), Neuromuscular disease, Child health, Cystic fibrosis Best practice Source Type: research
Bronchodilators in wheezy under 2-year-olds: when and which (if any)?
Clinical case Amy is 13 months old and presented to the children's emergency department with a 5-week history of wheezing. Her parents explain that they have seen her general practitioner twice and attended the local walk-in centre three times over the last month. She has been prescribed antibiotics and salbutamol both of which Amy ‘hates’. On examination, she had a dry cough with mild respiratory distress. She has occasional crepitations and widespread wheeze. Parents smoke ‘outside the house’ but neither has asthma. She is their first child. Clinically, she is well but parents would like to k...
Source: Archives of Disease in Childhood - Education and Practice - May 13, 2013 Category: Pediatrics Authors: Carroll, W. D., Srinivas, J. Tags: Epidemiologic studies, Editor's choice, Immunology (including allergy), Drugs: infectious diseases, Child health, Airway biology, Asthma, Drugs: respiratory system Pharmacy update Source Type: research
Two New Viruses Could Both Spark Global Outbreaks
Two respiratory viruses in different parts of the world have captured the attention of global health officials - a novel coronavirus in the Middle East and a new bird flu spreading in China. (Source: RWJF News Digest - Public Health)
Source: RWJF News Digest - Public Health - May 13, 2013 Category: American Health Source Type: news
Autonomic cardio‐respiratory reflex reactions and superselective ophthalmic arterial chemotherapy for retinoblastoma
ConclusionAdverse cardio‐respiratory reactions are commonly observed in SOAC for retinoblastoma. We believe that the adverse clinical signs represent an autonomic reflex response, akin to the trigemino‐cardiac or oculo‐respiratory reflexes, and all patients should be considered at‐risk. Reactions occur only during second or subsequent procedures and can be life‐threatening. The routine use of intravenous atropine does not seem to have altered the incidence or severity of these reactions. Anesthetists and interventional neuroradiologists involved in SOAC must be vigilant to ensure adverse reactions, when they deve...
Source: Pediatric Anesthesia - May 13, 2013 Category: Anesthesiology Authors: Trudie J. Phillips, Simon P. McGuirk, Hardeep K. Chahal, Judith Kingston, Fergus Robertson, Stefan Brew, Derek Roebuck, John L. Hungerford, Jane Herod Tags: Original Article Source Type: research

