Medicine RSS Search Engine

Respiratory Medicine research Respiratory Medicine research RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog.subscribe with FeedlySubscribe to this data using Feedly.

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 11.

Worsening Preoperative Heart Failure Is Associated with Mortality and Noncardiac Complications, But Not Myocardial Infarction after Noncardiac Surgery: A Retrospective Cohort Study.
CONCLUSIONS:: Worsening preoperative HF is associated with a significant increase in postoperative morbidity and mortality when controlling for other comorbidities. Although these likely have a multifactorial etiology, patients are much more likely to suffer from respiratory, renal, and infectious complications than cardiac complications. PMID: 24722256 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - April 9, 2014 Category: Anesthesiology Authors: Maile MD, Engoren MC, Tremper KK, Jewell E, Kheterpal S Tags: Anesth Analg Source Type: research

[Acute cough in infants: Impact on families and pharmacists of contraindications of the Agence nationale de sécurité du médicament et des produits de santé (ANSM).]
CONCLUSION: ANSM contraindications still have a limited impact on pharmacists and families. Therefore, efforts must be pursued to stop delivering cough medicines for infants. The information and educational campaigns should also involve parents and help to improve nasal wash use. PMID: 24726669 [PubMed - as supplied by publisher] (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - April 9, 2014 Category: Pediatrics Authors: Alauzet F, Blanc S, Montaudié I, Piccini-Bailly C, Berlioz-Baudoin M, Bégassat M, Albertini M, Giovannini-Chami L Tags: Arch Pediatr Source Type: research

Alios BioPharma snags $41 million for childhood respiratory drug work
Alios BioPharma Inc. will spend $41 million from a Series B round of funding on a mid-stage trial of its lead drug against respiratory syncytial virus and a handful of preclinical programs targeting influenza and the common cold. A quartet of existing corporate venture funds — Novo Ventures, GlaxoSmithKline's SR One, Roche Venture Fund and Novartis Ventures — as well as a new, undisclosed investor participated in the round, the South San Francisco company said. Alios' lead drug, AL-8176, is… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - April 8, 2014 Category: Biotechnology Authors: Ron Leuty Source Type: research

Increased levels of plasma galectin-9 in patients with influenza virus infection.
In conclusion, plasma Gal-9 could be a new biomarker for patients with influenza infection. PMID: 24695077 [PubMed - in process] (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - April 8, 2014 Category: Research Authors: Katoh S, Ikeda M, Shimizu H, Mouri K, Obase Y, Kobashi Y, Fukushima K, Hirashima M, Oka M Tags: Tohoku J Exp Med Source Type: research

Clinical characteristics and outcomes in critical patients with hemorrhagic fever with renal syndrome
Conclusion: The high fatality in critical patients with HFRS underscores the importance of clinicians' alertness to the occurrence of potentially fatal complications and changes in biochemical status to ensure that timely and systematically supportive treatment can be initiated when necessary. (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 8, 2014 Category: Infectious Diseases Authors: Hong DuPing-Zhong WangJing LiLu BaiHuan LiHai-Tao YuWei JiangYe ZhangJun-Ning WangXue-Fan Bai Source Type: research

Respiratory viruses associated with patients older than 50 years presenting with ILI in Senegal, 2009 to 2011
Conclusions: This pilot study demonstrates a variety of respiratory viruses in the elderly. It also highlights a high prevalence of these viruses in this age group. We speculate from these results that the impact of respiratory viruses other than influenza on the elderly has been considerably underestimated. A more exhaustive study seems necessary in order to provide a more complete picture of the burden of respiratory viruses on morbidity among adults over 50 years old in the sub-Saharan context. (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 8, 2014 Category: Infectious Diseases Authors: Ndongo DiaVincent RichardDavy KioriEl CisseFatoumata SarrAbdourahmane FayeDéborah GoudiabyOusmane DiopMbayame Niang Source Type: research

How communication affects prescription decisions in consultations for acute illness in children: a systematic review and meta-ethnography
Conclusions: Misunderstandings occurred due to parents and clinicians talking at cross purposes about the 'seriousness' of the illness and because parents' expressions of concern or requests for additional information were sometimes perceived as a challenge to the clinicians' diagnosis or treatment decision. This modifiable problem may be an important contribution to the unnecessary and unwanted prescribing of antibiotics. Primary care clinicians should be offered training to understand parent communication primarily as expressions of concern or attempts at understanding and always to check rather than infer parental expec...
Source: BMC Family Practice - April 8, 2014 Category: Primary Care Authors: Christie CabralJeremy HorwoodAlastair HayPatricia Lucas Source Type: research

Comparison of same day diagnostic tools including Gene Xpert and unstimulated IFN-gamma for the evaluation of pleural tuberculosis: a prospective cohort study
Conclusion: The usefulness of Xpert MTB/RIF to diagnose pleural TB is limited by its poor sensitivity. IFN-gamma is an excellent rule-in test and, compared to ADA, has significantly better sensitivity and rule-out value in a TB-endemic setting. (Source: BMC Pulmonary Medicine - Latest articles)
Source: BMC Pulmonary Medicine - Latest articles - April 8, 2014 Category: Respiratory Medicine Authors: Richard MeldauJonny PeterGrant TheronGreg CalligaroBrian AllwoodGreg SymonsHoosain KhalfeyGina NtombenhleUreshnie GovenderAnke BinderRichard van Zyl-SmitKeertan Dheda Source Type: research

Do heart and respiratory rate variability improve prediction of extubation outcomes in critically ill patients?
Altered heart and respiratory rate variability during spontaneous breathing trials are significantly associated with extubation failure; a predictive model provides optimal accuracy of prediction in all patients (Source: Critical Care)
Source: Critical Care - April 8, 2014 Category: Intensive Care Authors: Andrew SeelyAndrea BraviChristophe HerryGeoffrey GreenAndré LongtinTim RamsayDean FergussonLauralyn McIntyreDalibor KubelikDonna MaziakNiall FergusonSamuel BrownSangeeta MehtaClaudio MartinGordon RubenfeldFrank JaconoGari CliffordAnna FazekasJohn Marshal Source Type: research

Multilevel competing risk models to evaluate the risk of nosocomial infection
Conclusions: A combination of competing risks and multilevel models is required to understand direct and indirect risk factors for NI and distinguish patient-level from ICU-level factors. (Source: Critical Care)
Source: Critical Care - April 8, 2014 Category: Intensive Care Authors: Martin WolkewitzBen CooperMercedes Palomar-MartinezFrancisco Alvarez-LermaPedro Olaechea-AstigarragaAdrian BarnettStephan HarbarthMartin Schumacher Source Type: research

Delayed sequence intubation for management of respiratory failure in a 6‐year‐old child in a paediatric emergency department
(Source: Emergency Medicine Australasia)
Source: Emergency Medicine Australasia - April 8, 2014 Category: Emergency Medicine Authors: Ruth M Löllgen, Phillip Webster, Emma Lei, Andrew Weatherall Tags: Case Letter Source Type: research

Mitochondrial topoisomerase I (Top1mt) is a novel limiting factor of doxorubicin cardiotoxicity.
CONCLUSIONS: Our results provide evidence that mitochondrial topoisomerase I, Top1mt, which is conserved across vertebrates, is critical for cardiac tolerance to DOX and adaptive response to DOX cardiotoxicity. They also suggest the potential of Top1mt single nucleotide polymorphisms (SNP) testing to investigate patient susceptibility to DOX induced cardiotoxicity. PMID: 24714774 [PubMed - as supplied by publisher] (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - April 8, 2014 Category: Cancer & Oncology Authors: Khiati S, Dalla Rosa I, Sourbier C, Ma X, Rao VA, Neckers LM, Zhang H, Pommier Y Tags: Clin Cancer Res Source Type: research

Tuberculosis, pulmonary cavitation and matrix metalloproteinases.
Abstract Tuberculosis (TB), a chronic infectious disease of global importance, is facing the emergence of drug-resistant strains with few new drugs to treat the infection. Pulmonary cavitation, the hallmark of established disease, is associated with very high bacillary burden. Cavitation may lead to delayed sputum culture conversion, emergence of drug resistance, and transmission of the infection. The host immunological reaction to M. tuberculosis is implicated in driving the development of TB cavities. TB is characterized by a matrix degrading phenotype in which the activity of proteolytic matrix metalloproteinase...
Source: American Journal of Respiratory and Critical Care Medicine - April 8, 2014 Category: Respiratory Medicine Authors: Ong CW, Elkington PT, Friedland JS Tags: Am J Respir Crit Care Med Source Type: research

Comparison of same day diagnostic tools including Gene Xpert and unstimulated IFN-¿ for the evaluation of pleural tuberculosis: a prospective cohort study
Background: The accuracy of currently available same-day diagnostic tools (smear microscopy and conventional nucleic acid amplification tests) for pleural tuberculosis (TB) is sub-optimal. Newer technologies may offer improved detection. Methods: Smear-microscopy, adenosine deaminase (ADA), interferon gamma (IFN-γ), and Xpert MTB/RIF [using an unprocessed (1 ml) and centrifuged (~20 ml) sample] test accuracy was evaluated in pleural fluid from 103 consecutive patients with suspected pleural TB. Culture for M.tuberculosis and/or histopathology (pleural biopsy) served as the reference standard. Patients were followed prospe...
Source: BMC Pulmonary Medicine - Latest articles - April 8, 2014 Category: Respiratory Medicine Authors: Richard MeldauJonny PeterGrant TheronGreg CalligaroBrian AllwoodGreg SymonsHoosain KhalfeyGina NtombenhleUreshnie GovenderAnke BinderRichard van Zyl-SmitKeertan Dheda Source Type: research

Immune response to Bordetella pertussis is associated with season and undernutrition in Senegalese children.
CONCLUSIONS: These results are consistent with the hypothesis that environmental and nutritional factors modulate children's response to pertussis following natural infection or vaccination. PMID: 24726248 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - April 8, 2014 Category: Allergy & Immunology Authors: Gaayeb L, Pinçon C, Cames C, Sarr JB, Seck M, Schacht AM, Remoué F, Hermann E, Riveau G Tags: Vaccine Source Type: research

[Two cases of pneumocephalus following noninvasive continuous positive airway ventilation after transsphenoidal neurosurgery.]
We report two cases of pneumocephalus following the use of continuous positive airway pressure ventilation after transsphenoidal surgery. One patient had an obstructive sleep apnea and the other suffered acute respiratory failure. In both cases, pneumocephalus caused major morbidity and required specific treatment and prolonged considerably hospital stay. Based on these observations we believe new precautions in the use of noninvasive continuous positive airway pressure ventilation should be recommended. PMID: 24726003 [PubMed - as supplied by publisher] (Source: Annales Francaises d'Anesthesie et de Reanimation)
Source: Annales Francaises d'Anesthesie et de Reanimation - April 8, 2014 Category: Anesthesiology Authors: Zlotnik D, Taylor G, Simmoneau A, Viot-Blanc V, Devys JM Tags: Ann Fr Anesth Reanim Source Type: research

Protective Role of Amantadine in Mitochondrial Dysfunction and Oxidative Stress Mediated by Hepatitis C Virus Protein Expression.
In conclusion, these results support a role of amantadine in preserving cellular bioenergetics and redox homeostasis in HCV-infected cells and unveil an effect of the drug which might be exploited for a broader therapeutic utilization. PMID: 24726442 [PubMed - as supplied by publisher] (Source: Biochemical Pharmacology)
Source: Biochemical Pharmacology - April 8, 2014 Category: Drugs & Pharmacology Authors: Quarato G, Scrima R, Ripoli M, Agriesti F, Moradpour D, Capitanio N, Piccoli C Tags: Biochem Pharmacol Source Type: research

Respiratory manganese particle size, time-course and neurobehavioral outcomes in workers at a manganese alloy production plant.
Abstract The progression of manganism with chronic exposure to airborne manganese (Mn) is not well understood. Here, we further investigate the findings on exposure and neurobehavioral outcomes of workers from a silico- and ferromanganese production plant and non-exposed workers from the same community in 1990 and 2004, using a variety of exposure metrics that distinguish particle size and origin within the range of respirable airborne exposures. Mn exposure matrices for large respirable particulate (Mn-LRP, dust) and small respirable particulate (Mn-SRP, fume), based on process origins, were used together with det...
Source: Neurotoxicology - April 8, 2014 Category: Neurology Authors: Park RM, Bouchard MF, Baldwin M, Bowler R, Mergler D Tags: Neurotoxicology Source Type: research

IL-27R-Mediated Regulation of IL-17 Controls the Development of Respiratory Syncytial Virus-Associated Pathogenesis.
This study investigates the role of IL-27 signaling in respiratory syncytial virus (RSV) infection using IL-27Rα-deficient mice (IL-27rKO). Analysis of lungs from RSV-infected IL-27rKO mice showed exacerbation of mucus secretion compared with wild type, as well as enhanced expression of Muc5ac and Gob5 mRNA, markers of goblet cell metaplasia/hyperplasia. When compared with wild-type mice, RSV-challenged IL-27rKO mice had enhanced expression of Th17-associated cytokine IL-17a and an imbalance between Th1 and Th2 cytokine levels. Neutralization of IL-17 in RSV-infected IL-27rKO mice resulted in a significant decrease in the...
Source: The American Journal of Pathology - April 8, 2014 Category: Pathology Authors: de Almeida Nagata DE, Demoor T, Ptaschinski C, Ting HA, Jang S, Reed M, Mukherjee S, Lukacs NW Tags: Am J Pathol Source Type: research

Decline of ambient air pollution levels due to measures to control automobile emissions and effects on the prevalence of respiratory and allergic disorders among children in Japan.
CONCLUSIONS: The enforcement of measures to control automobile emissions based on the Automobile NOx/PM law was shown to have reduced air pollution and contributed to decreases in the prevalence of respiratory and allergic disorders in 3-year-old children. PMID: 24727639 [PubMed - as supplied by publisher] (Source: Environmental Research)
Source: Environmental Research - April 8, 2014 Category: Environmental Health Authors: Hasunuma H, Ishimaru Y, Yoda Y, Shima M Tags: Environ Res Source Type: research

Gold nanoparticles-based enhanced ELISA for respiratory syncytial virus
New J. Chem., 2014, Accepted ManuscriptDOI: 10.1039/C4NJ00253A, PaperLei Zhan, Wen Bi Wu, XIao Xi Yang, Cheng Zhi HuangRespiratory syncytial virus (RSV) mediates severe respiratory illness in infants and young children worldwide, and it is also a significant pathogen of the elderly and immune compromised. Due to low...The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - New J. Chem. latest articles)
Source: RSC - New J. Chem. latest articles - April 7, 2014 Category: Chemistry Authors: Lei Zhan Source Type: research

Positional effects on lung mechanics of ventilated preterm infants with acute and chronic lung disease
ConclusionsOn short‐term basis, prone positioning does not offer significant advantages in lung mechanics in mechanically ventilated infants with RDS, while it is associated with lower Rrs values in patients with evolving BPD. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - April 7, 2014 Category: Respiratory Medicine Authors: V. Vendettuoli, C. Veneroni, E. Zannin, D. Mercadante, P. Matassa, A. Pedotti, M. Colnaghi, R. L. Dellacà, F. Mosca Tags: Original Article: Neonatal Lung Disease Source Type: research

Long term outcome of tonsillar regrowth after partial tonsillectomy in children with obstructive sleep apnea
Conclusion: Partial tonsillectomy is sufficient to relieve obstruction while maintaining immunological function. This procedure has several post-operative advantages. Palatine tonsils infrequently regrow. Risk factors include young age, upper respiratory tract infections, history of allergy, and history of acute tonsillitis prior to regrowth. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - April 7, 2014 Category: ENT & OMF Authors: Qingfeng Zhang, Dawei Li, Hui Wang Tags: General Otolaryngology Source Type: research

70 Year Old Male: Short of Breath
  Good morning sports fans! You are dispatched to the residence of a 70 year old male, complaining of “shortness of breath”. You pull up to a well kept home, and are met at the front door by the patient’s wife. She tells you that her husband came home from the hospital yesterday after cosmetic eye surgery. You are led into the kitchen, and find your patient sitting in a chair at the kitchen table. There is an eye patch over his right eye. He appears to be in moderate respiratory distress. His color is ok, but you note he can only speak in short sentences. He tells you that he was fine until this morn...
Source: EMS 12-Lead - April 7, 2014 Category: Cardiology Authors: David Baumrind Tags: ems-health-safety ems-topics patient-management Training training-development case study Source Type: research

Glibenclamide in patients with poorly controlled type 2 diabetes: a 12-week, prospective, single-center, open-label, dose-escalation study
Rambiritch V, Maharaj B, Naidoo P (Source: International Journal of COPD)
Source: International Journal of COPD - April 7, 2014 Category: Respiratory Medicine Source Type: research

Exploring the heterogeneity of effects of corticosteroids on acute respiratory distress syndrome: a systematic review and meta-analysis
Routine use of corticosteroids is not recommended for acute respiratory distress syndrome (ARDS) as they do not improve long term outcomes and may even cause harm in certain subgroups of patients. (Source: Critical Care)
Source: Critical Care - April 7, 2014 Category: Intensive Care Authors: Sheng-Yuan RuanHsien-Ho LinChun-Ta HuangPing-Hung KuoHuey-Dong WuChong-Jen Yu Source Type: research

Secretory leukocyte protease inhibitor modulates urethane-induced lung carcinogenesis
Secretory leukocyte protease inhibitor (SLPI), 11.7 kDa serine protease inhibitor, is produced primarily in the respiratory tract, but it is often elevated in lung, head/neck and ovarian cancers. SLPI expression in relation to cancer progression, metastasis and invasion has been studied extensively in non-small cell lung cancer. However, the role of SLPI during the early stages of carcinogenesis remains unknown. We hypothesized that SLPI is required from the initiation and promotion to the progression of lung carcinogenesis. A skin allograft model using SLPI-knockout (SLPI-KO) mice and short hairpin RNA-treated cells was u...
Source: Carcinogenesis - April 7, 2014 Category: Cancer & Oncology Authors: Jan Treda, C., Fukuhara, T., Suzuki, T., Nakamura, A., Zaini, J., Kikuchi, T., Ebina, M., Nukiwa, T. Tags: Original Manuscript Source Type: research

Acute respiratory distress syndrome following straightforward pulmonary vein isolation
(Source: Europace)
Source: Europace - April 7, 2014 Category: Cardiology Authors: Novak, J., Segal, O. R. Tags: CASE EXPRESS REPORTS Source Type: research

Prophylactic effect of herbal-marine compound (HESA-A) on influenza A virus infectivity
Conclusion: In conclusion, HESA-A is significantly effective against influenza replication in prophylaxis application affecting the virus penetration/adsorption to the cell without any toxic effect on the cell viability. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - April 7, 2014 Category: Complementary Medicine Authors: Parvaneh MehrbodAini IderisAbdul OmarMohd Hair-Bejo Source Type: research

Shanghai fever: a distinct Pseudomonas aeruginosa enteric disease
Conclusions Shanghai fever is a sporadic community-acquired disease of previously healthy infants that manifests as sepsis associated with P aeruginosa enteric disease. Both host and microbial factors play a role in pathogenesis. (Source: Gut)
Source: Gut - April 7, 2014 Category: Gastroenterology Authors: Chuang, C.-H., Wang, Y.-H., Chang, H.-J., Chen, H.-L., Huang, Y.-C., Lin, T.-Y., Ozer, E. A., Allen, J. P., Hauser, A. R., Chiu, C.-H. Tags: Diarrhoea, Open access Enteric infections Source Type: research

Examining pediatric emergency home ventilation practices in home health nurses: Opportunities for improved care
ConclusionsNurses did not perform well in case‐based ventilator alarm scenarios. Length of nursing experience did not differentiate greater knowledge. It is clear that nurses require and want more training in emergency‐based HMV. Recommendations for an enhanced curriculum are suggested. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - April 7, 2014 Category: Respiratory Medicine Authors: Sheila S. Kun, Virginia N. Beas, Thomas G. Keens, Sally S.L. Ward, Jeffrey I. Gold Tags: Original Article: Other Source Type: research

Paradoxical immune reconstitution inflammatory syndrome presenting as acute respiratory distress syndrome in a non‐HIV immunosuppressed sarcoidosis patient
(Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - April 7, 2014 Category: Rheumatology Authors: Vishal Dahya, Moti Ramgopal, Jeffrey Glickman Tags: Correspondence Source Type: research

Prevalence, distribution and transfer of small {beta}-lactamase-containing plasmids in Swedish Haemophilus influenzae
Conclusions Small β-lactamase-encoding plasmids constitute a significant mechanism for β-lactam resistance in H. influenzae and can spread through clonal expansion of resistant clones as well as through horizontal plasmid transfer. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - April 7, 2014 Category: Microbiology Authors: Fleury, C., Resman, F., Rau, J., Riesbeck, K. Tags: Original research Source Type: research

Transcriptional approach to study porcine tracheal epithelial cells individually or dually infected with swine influenza virus and Streptococcus suis
Conclusion: Influenza virus would replicate in the respiratory epithelium and induce an inflammatory infiltrate comprised of mononuclear cells and neutrophils. In a co-infection situation, although these cells would be unable to phagocyte and kill S. suis, they are highly activated by this pathogen. S. suis is not considered a primary pulmonary pathogen, but an exacerbated production of proinflammatory mediators during a co-infection with influenza virus may be important in the pathogenesis and clinical outcome of S. suis-induced respiratory diseases. (Source: BMC Veterinary Research - Latest articles)
Source: BMC Veterinary Research - Latest articles - April 7, 2014 Category: Veterinary Research Authors: Yuan DangClaude LachanceYingchao WangCarl GagnonChristian SavardMariela SeguraDaniel GrenierMarcelo Gottschalk Source Type: research

Killing of Mycobacterium avium by lactoferricin peptides: improved activity of arginine- and D-amino acids-containing molecules.
Abstract Mycobacterium avium causes respiratory disease in susceptible individuals, as well as disseminated infections in immunocompromised hosts, being an important cause of morbidity and mortality among these populations. Current therapies consist of a combination of antibiotics taken for at least six months, with no more than 60% overall clinical success. Furthermore, mycobacterial antibiotic resistance is increasing worldwide, urging the need to develop novel classes of antimicrobial drugs. One potential and interesting alternative strategy is the use of antimicrobial peptides (AMP). These are present in almost...
Source: Antimicrobial Agents and Chemotherapy - April 7, 2014 Category: Microbiology Authors: Silva T, Magalhães B, Maia S, Gomes P, Nazmi K, Bolscher JG, Rodrigues PN, Bastos M, Gomes MS Tags: Antimicrob Agents Chemother Source Type: research

Human Internal Jugular Valve M-mode Ultrasound Characterization.
Abstract In humans the mechanism governing the internal jugular vein (IJV) valve opening and closure is still unclear. M-mode is used in echo-cardiology for the heart valves assessment. Sometimes it was performed also in deep peripheral veins and in vena cava assessment, but never in the IJV valve. Aim of the present study is to investigate the IJV valves physiology in healthy volunteers, by means of both B and M-mode ultrasound. Eighty-three (83) healthy volunteers (35 Male, 48 Female, 25.7±6.7 y.o.), for a total of 166 IJVs, were enrolled. The entire cohort underwent IJVs high-resolution B and M-mode evaluation,...
Source: Current Neurovascular Research - April 7, 2014 Category: Neurology Authors: Menegatti E, Tessari M, Gianesini S, Vannini ME, Sisini F, Zamboni P Tags: Curr Neurovasc Res Source Type: research

[Acute cough in infants: Impact of national guidelines on medical practices in a French department.]
CONCLUSION: Continued educational and informative campaigns are therefore needed to stop medical prescriptions of cough medicines for infants, which should also involve parents. PMID: 24721414 [PubMed - as supplied by publisher] (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - April 7, 2014 Category: Pediatrics Authors: Alauzet F, Banide MC, Pailhes C, Blanc S, Montaudié I, Piccini-Bailly C, Berlioz-Baudoin M, Bégassat M, Albertini M, Giovannini-Chami L Tags: Arch Pediatr Source Type: research

Macrolide Antibiotics and the Risk of Cardiac Arrhythmias.
Abstract Randomized, controlled trials have demonstrated that chronic therapy with macrolide antibiotics reduces the morbidity of patients with cystic fibrosis, non-cystic fibrosis bronchiectasis, chronic obstructive pulmonary disease and nontuberculous mycobacterial infections. Lower levels of evidence indicate that chronic macrolides are also effective in patients with panbronchiolitis, and bronchiolitis obliterans and rejection after lung transplant. Macrolides are known to cause torsade des pointes and other ventricular arrhythmias and a recent observational study prompted the FDA to strengthen the Warnings and...
Source: American Journal of Respiratory and Critical Care Medicine - April 7, 2014 Category: Respiratory Medicine Authors: Albert RK, Schuller JL, the COPD Clinical Research Network Tags: Am J Respir Crit Care Med Source Type: research

Endothelial progenitor cells and a SDF-1α analogue synergistically improve survival in sepsis.
Conclusions: EPCs and CTCE represent important potential therapeutic strategies in sepsis. PMID: 24707934 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 7, 2014 Category: Respiratory Medicine Authors: Fan H, Goodwin AJ, Chang E, Zingarelli B, Borg K, Guan S, Halushka PV, Cook JA Tags: Am J Respir Crit Care Med Source Type: research

Investigating the role of NOD-Like Receptors in Bacterial Lung Infection.
This article addresses our current understanding of the structure and function of NLR family members, highlighting recent advances and gaps in knowledge with the specific focus on immune responses in the respiratory tract during bacterial infection. Further advances in exploring cellular and molecular responses to bacterial pathogens are critical to develop improved strategies to treating and preventing devastating infectious diseases in the lung. PMID: 24707903 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 7, 2014 Category: Respiratory Medicine Authors: Leissinger M, Kulkarni R, Zemans RL, Downey GP, Jeyaseelan S Tags: Am J Respir Crit Care Med Source Type: research

Tuberculous Pleural Effusion.
Abstract Tuberculous pleural effusion (TBPE) is the most common form of extrapulmonary tuberculosis (TB) in Spain, and is one of the most frequent causes of pleural effusion. Although the incidence has steadily declined (4.8 cases/100,000population in 2009), the percentage of TBPE remains steady with respect to the total number of TB cases (14.3%-19.3%). Almost two thirds are men, more than 60% are aged between 15-44years, and it is more common in patients with human immunodeficiency virus. The pathogenesis is usually a delayed hypersensitivity reaction. Symptoms vary depending on the population (more acute in youn...
Source: Archivos de Bronconeumologia - April 7, 2014 Category: Respiratory Medicine Authors: Ferreiro L, San José E, Valdés L Tags: Arch Bronconeumol Source Type: research

Cashew nut roasting: Chemical characterization of particulate matter and genotocixity analysis.
CONCLUSIONS: This study demonstrated that artisanal cashew nut roasting is a serious occupational problem, with harmful effects on workers׳ health. Those involved in this activity are exposed to higher PM2.5 concentrations and to 12 PAHs considered potentially mutagenic and/or carcinogenic. The Trad-MCN with T. pallida was sensitive and efficient in evaluating the genotoxicity of the components and other nuclear alterations may be used as effective biomarkers of DNA damage. PMID: 24721132 [PubMed - as supplied by publisher] (Source: Environmental Research)
Source: Environmental Research - April 7, 2014 Category: Environmental Health Authors: de Oliveira Galvão MF, de Melo Cabral T, de André PA, de Fátima Andrade M, de Miranda RM, Saldiva PH, de Castro Vasconcellos P, de Medeiros SR Tags: Environ Res Source Type: research

Spirosoma arcticum sp.nov., isolated from high Arctic glacial till.
Abstract A novel orange pigmented strain, designated R2-35T, was isolated from a glacier till near Ny-Alesund, Svalbard Archipelago, Norway. The cells were aerobic, Gram-negative, rod-shaped and sometimes filamentous. Growth occurred at 4-28 (optimum, 20), at pH 7.0-9.0 (optimum, pH 8.0) and with 0-1% NaCl. Phylogenetic analysis based on 16S rDNA gene sequences indicated that strain R2-35T belonged to the genus Spirosoma with the sequence similarity to the related species ranged from 91.65 to 95.19%. Strain R2-35T contained C16:0 (10.7%), C18:0 (9.2%), C16:1 ω5c (16.5%) and summed feature 3 (C16:1 ω6c and/or C16:...
Source: International Journal of Systematic and Evolutionary Microbiology - April 7, 2014 Category: Microbiology Authors: Chang X, Jiang F, Wang T, Kan W, Qu Z, Ren L, Fang C, Peng F Tags: Int J Syst Evol Microbiol Source Type: research

Mucilaginibacter pineti sp. nov., isolated from Pinus pinaster wood in mixed grove of pines trees.
Abstract Bacterial strain M47C3BT was isolated from the endophytic microbial community of a Pinus pinaster tree branch from a mixed grove of pines. Phylogenetic analysis of the 16S rRNA gene sequences showed that this organism represented one distinct branch within the family Sphingobacteriaceae, most closely related with the genus Mucilaginibacter. The strain M47C3BT form a distinct lineage, closely related to the species Mucilaginibacter dorajii KACC 14556 T with which it shared 97.2% 16S rRNA gene sequence similarity. The other members of genus Mucilaginibacter included in the same clade are M. lappiensis ATCC B...
Source: International Journal of Systematic and Evolutionary Microbiology - April 7, 2014 Category: Microbiology Authors: Paiva G, Abreu P, Proença DN, Santos S, Nobre MF, Morais PV Tags: Int J Syst Evol Microbiol Source Type: research

Sendai virus-based RSV vaccine protects against RSV challenge in an in vivo maternal antibody model.
Abstract Respiratory syncytial virus (RSV) is the cause of significant morbidity and mortality among infants, and despite decades of research there remains no licensed vaccine. SeVRSV is a Sendai virus (SeV)-based live intranasal vaccine that expresses the full length RSV fusion (F) gene. SeV is the murine counterpart of human parainfluenza virus type 1. Given that the target population of SeVRSV is young infants, we questioned whether maternal antibodies typical of this age group would inhibit SeVRSV vaccine efficacy. After measuring SeV- and RSV-specific serum neutralizing antibody titers in human infants, we mat...
Source: Vaccine - April 7, 2014 Category: Allergy & Immunology Authors: Jones BG, Sealy RE, Surman SL, Portner A, Russell CJ, Slobod KS, Dormitzer PR, Devincenzo J, Hurwitz JL Tags: Vaccine Source Type: research