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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 11.

The up-rise in e-cigarette use - friend or foe?
PMID: 27184395 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2016 Category: Respiratory Medicine Authors: Lundbäck B, Katsaounou P, Lötvall J Tags: Respir Res Source Type: research

Determinants and impact of suboptimal asthma control in Europe: The INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study.
CONCLUSIONS: The cross-sectional phase results confirm that suboptimal control is frequent and has a high individual and economic impact. TRIAL REGISTRATION: The clinicaltrials.gov identifier is NCT01567280 . PMID: 27179604 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2016 Category: Respiratory Medicine Authors: Braido F, Brusselle G, Guastalla D, Ingrassia E, Nicolini G, Price D, Roche N, Soriano JB, Worth H, LIAISON Study Group Tags: Respir Res Source Type: research

Unmasking Granulomatous Pneumocystis jirovecii Pneumonia with Nodular Opacity in an HIV-Infected Patient after Initiation of Antiretroviral Therapy.
This report describes an intriguing case of granulomatous PJP with pulmonary nodules after commencing antiretroviral therapy (ART) in an HIV-infected patient without respiratory signs or symptoms. Diagnosis of granulomatous PJP was only achieved through thoracoscopic lung biopsy. This case suggests that granulomatous PJP should be considered in the differential diagnosis of pulmonary nodules in HIV-infected patients for unmasking immune reconstitution inflammatory syndrome manifestation after initiation of ART. PMID: 27189304 [PubMed - as supplied by publisher] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - May 19, 2016 Category: Universities & Medical Training Authors: Kim HW, Heo JY, Lee YM, Kim SJ, Jeong HW Tags: Yonsei Med J Source Type: research

Comparison of Predicted Total Lung Capacity and Total Lung Capacity by Computed Tomography in Lung Transplantation Candidates.
CONCLUSION: Regardless of pulmonary disease pattern, TLC(CT) was smaller than pTLC, and it was more apparent in restrictive lung disease. Therefore, we should consider the difference between TLC(CT) and pTLC, as well as lung disease patterns of candidates, in lung size matching for LTx. PMID: 27189292 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - May 19, 2016 Category: Universities & Medical Training Authors: Hwang SH, Lee JG, Kim TH, Paik HC, Park CH, Haam S Tags: Yonsei Med J Source Type: research

Helmet CPAP versus Oxygen Therapy in Hypoxemic Acute Respiratory Failure: A Meta-Analysis of Randomized Controlled Trials.
CONCLUSION: The results of this meta-analysis suggest that helmet CPAP improves oxygenation and reduces mortality and intubation rates in hARF. However, the significant clinical and statistical heterogeneity of the literature implies that large RCTs are needed to determine the role of helmet CPAP in different hypoxemic ARF populations. PMID: 27189288 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - May 19, 2016 Category: Universities & Medical Training Authors: Luo Y, Luo Y, Li Y, Zhou L, Zhu Z, Chen Y, Huang Y, Chen X Tags: Yonsei Med J Source Type: research

In Hot Pursuit of the First Vaccine Against Respiratory Syncytial Virus.
Abstract Human respiratory syncytial virus (RSV) is the leading cause of severe lower respiratory tract infection, such as bronchiolitis, bronchitis, or pneumonia, in both infants and the elderly. Despite the global burden of diseases attributable to RSV infection, no clinically approved vaccine is available, and a humanized monoclonal antibody for prophylaxis is not readily affordable in developing countries. There are several hurdles to the successful development of RSV vaccines: immune-vulnerable target populations such as premature infants, pregnant women, and immunocompromised people; safety concerns associate...
Source: Yonsei Medical Journal - May 19, 2016 Category: Universities & Medical Training Authors: Kim JY, Chang J Tags: Yonsei Med J Source Type: research

Injury and illness surveillance at the International Sailing Federation Sailing World Championships 2014.
CONCLUSIONS: The Olympic classes introduced since 2000 (49erFX, 49er, Nacra 17) have resulted in a rise in injuries. PMID: 27190229 [PubMed - in process] (Source: British Journal of Sports Medicine)
Source: British Journal of Sports Medicine - May 19, 2016 Category: Sports Medicine Authors: Tan B, Leong D, Vaz Pardal C, Lin CY, Kam JW Tags: Br J Sports Med Source Type: research

The effect of glycyrrhizic acid on traumatic spinal cord injury in rats.
Authors: Sehitoglu MH, Guven M, Yüksel Y, Akman T, Bozkurt Aras A, Farooqi AA, Cosar M Abstract Spine injury associated with traumatic spinal cord injury eventuates in oxidative stress, inflammation and neuronal apoptosis. The aim of this study is to find out whether the glycyrrhizic acid treatment protects spinal cord from traumatic injuries in rats. To this end, the rats were divided into three groups: group I; control group (no drug or operation, n=8), group II; traumatic spinal cord injury group (TSCI, n=8) and group III; glycyrrhizic acid group (TSCI-GA, 80 mg/kg, n=8). Total laminectomy was performed at T10 ...
Source: Cellular and Molecular Biology - May 19, 2016 Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research

[Night-to-night variability of the obstructive sleep apnoea-hypopnoea syndrome].
CONCLUSION: This study demonstrates that the AHI in OSAHS patients is well correlated between two consecutive nights. However, a significant individual variability should be taken into consideration, especially when AHI is used in the classification of OSAHS or as a criterion of therapeutic success. PMID: 27179365 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - May 19, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

Plasma apelin level in patients with restless legs syndrome and its association with periodic leg movements
Conclusions RLS patients especially those with a PLMI above 15 have low plasma apelin levels independent of disease severity and sleep parameters such as sleep duration and quality. Decreased apelin levels may explain the increased risk for vascular diseases in those patients. (Source: Sleep and Breathing)
Source: Sleep and Breathing - May 19, 2016 Category: Respiratory Medicine Source Type: research

Sleep pattern changes in patients with connective tissue diseases
Conclusion Obstructive sleep apnea is commonly associated with CTD patients. Co-existence of OSA in CTD patients may influence the disease activity and the level of circulating inflammatory markers. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - May 19, 2016 Category: Respiratory Medicine Source Type: research

Dexmedetomidine vs propofol-remifentanil conscious sedation for awake craniotomy: a prospective randomized controlled trial
Conclusions Quality of intraoperative brain mapping and efficacy of sedation with dexmedetomidine were similar to propofol-remifentanil during AC for supratentorial tumour resection. Dexmedetomidine was associated with fewer respiratory adverse events. Clinical trial registration NCT01545297. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - May 19, 2016 Category: Anesthesiology Authors: Goettel, N., Bharadwaj, S., Venkatraghavan, L., Mehta, J., Bernstein, M., Manninen, P. H. Tags: Neurosciences And Neuroanaesthesia Source Type: research

Increasing positive end-expiratory pressure (re-)improves intraoperative respiratory mechanics and lung ventilation after prone positioning
Conclusions Respiratory system mechanics change substantially between supine and prone posture, which is not demonstrated in routine measurements. The intratidal compliance analysis suggests that in most patients a PEEP above commonly used settings is necessary to avoid alveolar collapse in the prone position. Clinical trial registration DRKS 00005692. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - May 19, 2016 Category: Anesthesiology Authors: Spaeth, J., Daume, K., Goebel, U., Wirth, S., Schumann, S. Tags: Respiration And The Airway Source Type: research

High inspired oxygen concentration increases the speed of onset of remifentanil-induced respiratory depression
(Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - May 19, 2016 Category: Anesthesiology Authors: Dahan, A., Douma, M., Olofsen, E., Niesters, M. Tags: Correspondence Source Type: research

Determinants of All-Cause Mortality and Incidence of Cardiovascular Disease (2009 to 2013) in Older Adults: The Ikaria Study of the Blue Zones
Conclusion: Heart function markers in addition to antioxidant dietary factors were placed in this puzzle of CVD morbidity. (Source: Angiology)
Source: Angiology - May 19, 2016 Category: Cardiology Authors: Chrysohoou, C., Pitsavos, C., Lazaros, G., Skoumas, J., Tousoulis, D., Stefanadis, C., on behalf of the Ikaria Study Investigators Tags: Cardiovascular Disease Source Type: research

Antiviral activity of hydroalcoholic extract from Eupatorium perfoliatum L. against the attachment of influenza A virus
Conclusion Hydroalcoholic extracts from the aerial parts of E. perfoliatum and its main active polyphenolic constituents protect cells from IAV infection by inhibiting viral attachment to the host cells. The extract appears to be a promising expansion of the currently available anti-influenza agents. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - May 19, 2016 Category: Drugs & Pharmacology Source Type: research

Is there a role for humidified heated high-flow nasal cannula therapy in paediatric emergency departments?
Conclusions HFNC therapy may have a role in the paediatric ED as an easily administered and well tolerated form of non-invasive respiratory support, but about one-third of patients required escalation to a higher level of respiratory support. Further studies should assess the safety profile of HFNC in larger series, and define the role of HFNC in key respiratory conditions compared with other possible interventions. (Source: Emergency Medicine Journal)
Source: Emergency Medicine Journal - May 19, 2016 Category: Emergency Medicine Authors: Long, E., Babl, F. E., Duke, T. Tags: Bronchiolitis, TB and other respiratory infections, Child health, Asthma, Bronchitis Original article Source Type: research

Antimicrobial susceptibility of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis isolated from community-acquired respiratory tract infections in China: Results from the CARTIPS Antimicrobial Surveillance Program
This study investigated the antimicrobial susceptibilities of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis isolates causing adult community-acquired respiratory tract infections (CARTIs) in China. A multicentre resistance surveillance study (CARTIPS) investigating 1046 clinical isolates from 19 hospitals in China was conducted from 2013 to 2014. Based on the minimum inhibitory concentration (MIC) breakpoints of oral penicillin, the percentages of penicillin-resistant, penicillin-intermediate and penicillin-susceptible S. pneumoniae were 44.1%, 13.7%, and 42.2%, respectively. The rates of penic...
Source: Journal of Global Antimicrobial Resistance - May 19, 2016 Category: Infectious Diseases Source Type: research

Strengthening the afferent limb of rapid response systems: an educational intervention using web-based learning for early recognition and responding to deteriorating patients
Conclusions A web-based educational programme developed for hospital nurses to strengthen the afferent limb of the RRS significantly increased their knowledge and performances in assessing, managing and reporting clinical deterioration. (Source: BMJ Quality and Safety)
Source: BMJ Quality and Safety - May 19, 2016 Category: Journals (General) Authors: Liaw, S. Y., Wong, L. F., Ang, S. B. L., Ho, J. T. Y., Siau, C., Ang, E. N. K. Tags: Original research Source Type: research

Prenatal maternal psychosocial stress and risk of asthma and allergy in their offspring: protocol for a systematic review and meta-analysis
npj Primary Care Respiratory Medicine, Published online: 19 May 2016; doi:10.1038/npjpcrm.2016.21 (Source: npj Primary Care Respiratory Medicine)
Source: npj Primary Care Respiratory Medicine - May 19, 2016 Category: Primary Care Authors: Catherine FlaniganAziz SheikhBright I Nwaru Source Type: research

Outcomes of lung cancer surgery in patients with coronary artery disease: a decade of experience at a single institution
Conclusions Patients with NSCLC and a history of CAD are at higher risk of complications after pulmonary resection. Combined decreased organ function is a risk factor for postoperative complications. CAD did not influence the long-term outcomes of patients after pulmonary resection for NSCLC. (Source: Surgery Today)
Source: Surgery Today - May 19, 2016 Category: Surgery Source Type: research

Prospective exploratory muscle biopsy, imaging, and functional assessment in patients with late-onset Pompe disease treated with alglucosidase alfa: The EMBASSY Study
Conclusions This exploratory study provides novel insights into the histopathologic effects of ERT in late-onset Pompe disease patients. Ultrastructural examination of muscle biopsies demonstrated reduced lysosomal glycogen after ERT. Findings are consistent with stabilization of disease by ERT in treatment-naïve patients with late-onset Pompe disease. (Source: Molecular Genetics and Metabolism)
Source: Molecular Genetics and Metabolism - May 19, 2016 Category: Genetics & Stem Cells Source Type: research

East Coast Fever Caused by Theileria parva Is Characterized by Macrophage Activation Associated with Vasculitis and Respiratory Failure
by Lindsay M. Fry, David A. Schneider, Charles W. Frevert, Danielle D. Nelson, W. Ivan Morrison, Donald P. Knowles Respiratory failure and death in East Coast Fever (ECF), a clinical syndrome of African cattle caused by the apicomplexan parasite Theileria parva, has historically been attributed to pulmonary infiltration by infected lymphocytes. However, immunohistochemical staining of tissue from T. parva infected cattle revealed large numbers of CD3- and CD20-negative intralesional mononuclear cells. Due to this finding, we hypothesized that macrophages play an important role in Theileria parva disease pathogenesis. Data...
Source: PLoS One - May 19, 2016 Category: Biomedical Science Authors: Lindsay M. Fry Source Type: research

Avian thermoregulation in the heat: efficient evaporative cooling allows for extreme heat tolerance in four southern Hemisphere columbids [RESEARCH ARTICLE]
Andrew E. McKechnie, Maxine C. Whitfield, Ben Smit, Alexander R. Gerson, Eric Krabbe Smith, William A. Talbot, Todd J. McWhorter, and Blair O. WolfBirds show phylogenetic variation in the relative importance of respiratory versus cutaneous evaporation, but the consequences for heat tolerance and evaporative cooling capacity remain unclear. We measured evaporative water loss (EWL), resting metabolic rate (RMR) and body temperature (Tb) in four arid-zone columbids from southern African [Namaqua dove (Oena capensis, ~37 g), laughing dove (Spilopelia senegalensis, ~89 g) and Cape turtle dove (Streptopelia capicola, ~148 g)] an...
Source: Journal of Experimental Biology - May 19, 2016 Category: Biology Authors: McKechnie, A. E., Whitfield, M. C., Smit, B., Gerson, A. R., Smith, E. K., Talbot, W. A., McWhorter, T. J., Wolf, B. O. Tags: RESEARCH ARTICLE Source Type: research

Human parainfluenza virus types 1 to 4 in hospitalized children with acute lower respiratory infections in China
ConclusionHPIV‐4 is an important virus for children hospitalized with ALRTIs in China. HRV was the most common co‐infecting virus. Two genotypes for HPIV‐4 are prevalent, HPIV‐4a dominated. This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)
Source: Journal of Medical Virology - May 19, 2016 Category: Virology Authors: Ni‐guang Xiao, Zhao‐jun Duan, Zhi‐ping Xie, Li‐li Zhong, Sai‐zhen Zeng, Han‐Huang, Han‐chun Gao, Bing Zhang Tags: Research Article Source Type: research

Etiology, seasonality, and clinical characterization of viral respiratory infections among hospitalized children in Beirut, Lebanon
This study provides relevant facts on the circulatory pattern of respiratory viruses in Lebanon and the importance of using PCR as a useful tool for virus detection. Early diagnosis at the initial time of hospitalization may reduce the spread of the viruses in pediatric units. J. Med. Virol. © 2016 Wiley Periodicals, Inc. (Source: Journal of Medical Virology)
Source: Journal of Medical Virology - May 19, 2016 Category: Virology Authors: Mayda Finianos, Randi Issa, Martin D. Curran, Claude Afif, Maryam Rajab, Jihad Irani, Noha Hakimeh, Amal Naous, Marie‐Joelle Hajj, Pierre Hajj, Tamima El Jisr, Mira El Chaar Tags: Research Article Source Type: research

Sealing Effect of Cross-Linked Gelatin Glue in the Rat Lung Air Leak Model
Conclusions The sealing effect of gelatin glue was superior to that of fibrin glue, with or without a polyglycolic acid sheet. In addition, the gelatin glue only caused mild inflammation of the lung and was absorbed without any adverse foreign body response. These findings suggest that gelatin glue may be a therapeutically effective biomaterial for sealing lung wounds and restoring respiratory function. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 19, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

The Use of Hypothermic Circulatory Arrest During Heart Transplantation Does Not Worsen Posttransplant Survival
Conclusions The need for HCA during heart transplantation is rare but, when required, it is frequently a life-saving adjunct to cardiopulmonary bypass. However, patients who require HCA have higher rates of postoperative complications. Risk factors for needing HCA during transplantation include congenital heart disease and more than one prior sternotomies. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 19, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Descending Aortic Translocation for Relief of Distal Tracheal and Proximal Bronchial Compression
Conclusions A midline descending aorta can cause compression of the tracheal carina and proximal bronchi, with debilitating symptoms. Translocation of the descending aorta is a reliable procedure that relieves the compression and results in long-term resolution of symptoms. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 19, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Seizures as a rare but serious adverse effect of leukotriene receptor
Leukotriene receptor antagonists (LTRAs) are used widely in the treatment of allergic rhinitis and asthma in children.1,2 LTRAs are safe in combination with antihistamines in patients with chronic urticaria who respond inadequately to antihistamines alone.3 Several clinical trials have emphasized that LTRAs can be considered safe. Nevertheless, many adverse effects associated with LTRAs have been reported. Most of the adverse events are mild (headache, gastrointestinal disorders, pharyngitis, fatigue, upper respiratory tract infection, cutaneous rash, and reversible changes in the serum transaminase levels). (Source: Annal...
Source: Annals of Allergy, Asthma and Immunology - May 19, 2016 Category: Allergy & Immunology Authors: Semiha Bahceci Erdem, Sait Karaman, Hikmet Tekin Nacaroglu, Canan Sule Unsal Karkıner, Selcuk Yazıcı, Demet Can Tags: Letter Source Type: research

Extracorporeal Membrane Oxygenation for Pediatric Cardiac Failure: Review with a Focus on Unique Subgroups
Extracorporeal membrane oxygenation (ECMO) is a widely used form of mechanical circulatory support for infants and children with refractory cardiac and respiratory failure. The use of ECMO in infant and pediatric cardiac failure continues to increase over the last decade with 51% survival to discharge. Despite improvements in short term survival, ECMO remains an invasive and expensive therapy with significant associated complications and both short and long term sequelae. The focus of this review is to provide clinicians with a better understanding of the evolving indications, implementation, complications, outcomes and ut...
Source: Progress in Pediatric Cardiology - May 19, 2016 Category: Cardiology Authors: Katherine Cashen, Taemyn K. Hollis, Ralph E. Delius, Kathleen L. Meert Source Type: research

Survival Analysis Following Extracorporeal Membrane Oxygenation in Critically Ill Adults: A Nationwide Cohort Study.
CONCLUSIONS: -Regardless of initial pathology, patients requiring ECMO were critically ill with similar guarded prognoses. Those in the trauma group had somewhat better outcomes. Determining the efficacy and cost-effectiveness of ECMO should be a critical future goal. PMID: 27199466 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - May 19, 2016 Category: Cardiology Authors: Chang CH, Chen HC, Caffrey JL, Hsu J, Lin JW, Lai MS, Chen YS Tags: Circulation Source Type: research

Novosphingobium naphthae sp. nov., from oil-contaminated soil.
Abstract During the study of hydrocarbon-degrading bacteria in the oil-contaminated soil of Gunsan, North Jeolla Province, South Korea, a light grey-pigmented, Gram-staining negative, aerobic, non-motile, and rod shaped bacterium, designated strain D39T, was isolated. This strain was non-sporulating, catalase-negative, and oxidase-positive. It was able to grow at 20-37°C, pH 5.5-8.5, and 0-1% (w/v) NaCl concentration. This strain was taxonomically characterized by a polyphasic approach. Based on the results of 16S rRNA gene sequence analysis, strain D39T belongs to the genus Novosphingobium and is closely related ...
Source: International Journal of Systematic and Evolutionary Microbiology - May 19, 2016 Category: Microbiology Authors: Chaudhary DK, Kim J Tags: Int J Syst Evol Microbiol Source Type: research

Short-term exposure to high ambient air pollution increases airway inflammation and respiratory symptoms in chronic obstructive pulmonary disease patients in Beijing, China.
CONCLUSIONS: FeH2S may serve as a novel biomarker to detect adverse respiratory effects of air pollution. Our results provide potential important public health implications that ambient air pollution may pose risk to respiratory health in the context of high pollution levels in densely-populated cities in the developing world. PMID: 27209003 [PubMed - as supplied by publisher] (Source: Environment International)
Source: Environment International - May 19, 2016 Category: Environmental Health Authors: Wu S, Ni Y, Li H, Pan L, Yang D, Baccarelli AA, Deng F, Chen Y, Shima M, Guo X Tags: Environ Int Source Type: research

Occupational exposure to asthmagens and adult onset wheeze and lung function in people who did not have childhood wheeze: A 50-year cohort study.
CONCLUSIONS: This longitudinal study confirmed previous findings of increased risks of adult onset wheezing illness with occupational exposure to specific asthmagens. A novel finding was the identification of food-related asthmagens and biocides/fungicides as potential new occupational risk factors for lung function impairment in adults without childhood wheeze. PMID: 27209001 [PubMed - as supplied by publisher] (Source: Environment International)
Source: Environment International - May 19, 2016 Category: Environmental Health Authors: Tagiyeva N, Teo E, Fielding S, Devereux G, Semple S, Douglas G Tags: Environ Int Source Type: research

Influence of torso and arm positions on chest examinations by electrical impedance tomography
Electrical impedance tomography (EIT) is increasingly used in patients suffering from respiratory disorders during pulmonary function testing (PFT). The EIT chest examinations often take place simultaneously to conventional PFT during which the patients involuntarily move in order to facilitate their breathing. Since the influence of torso and arm movements on EIT chest examinations is unknown, we studied this effect in 13 healthy subjects (37  ±  4 years, mean age  ±  SD) and 15 patients with obstructive lung diseases (72  ±  8 years) during stable tidal breathing. We carried out the exami...
Source: Physiological Measurement - May 19, 2016 Category: Physiology Authors: B Vogt, L Mendes, I Chouvarda, E Perantoni, E Kaimakamis, T Becher, N Weiler, V Tsara, R P Paiva, N Maglaveras and I Frerichs Source Type: research

Advances in Understanding Bronchiolitis Obliterans after lung transplantation.
Abstract Bronchiolitis obliterans syndrome (BOS) remains a major complication after lung transplantation, causing significant morbidity and mortality in a majority of the recipients. BOS is believed to be the clinical correlate of chronic allograft dysfunction and is defined as an obstructive pulmonary function defect in the absence of other identifiable causes, mostly not amenable to treatment. Recently, it has become clear that BOS is not the only form of chronic allograft dysfunction and that other clinical phenotypes exist, however we will focus exclusively on BOS. Radiology typically demonstrates air trapping,...
Source: Chest - May 19, 2016 Category: Respiratory Medicine Authors: Verleden SE, Sacreas A, Vos R, Vanaudenaerde BM, Verleden GM Tags: Chest Source Type: research

1,2:3,4-Diepoxybutane Induces Multipolar Mitosis in Cultured Human Lymphocytes
1,3-Butadiene, a colorless gas regularly used in the production of plastics, thermoplastic resins, and styrene-butadiene rubber, poses an increased leukemia mortality risk to workers in this field. 1,3-Butadiene is also produced by incomplete combustion of motor fuels or by tobacco smoking. It is absorbed principally through the respiratory system and metabolized by several enzymes rendering 1,2:3,4-diepoxybutane (DEB), which has the highest genotoxic potency of all metabolites of 1,3-butadiene. DEB is considered a carcinogen mainly due to its high potential as clastogen, which induces structural chromosome aberrations suc...
Source: Cytogenetic and Genome Research - May 18, 2016 Category: Genetics & Stem Cells Source Type: research

Feasibility of Exercise Training in Cancer Patients Scheduled for Elective Gastrointestinal Surgery
Conclusion: This exercise program in patients awaiting oncological surgery is feasible in terms of participation and adherence. Inspiratory muscle function improved significantly as a result of inspiratory muscle training. The exercise program however failed to result in improved aerobic capacity and peripheral muscle strength, probably due to the limited number of training sessions as a result of the restricted time interval between screening and surgery.Dig Surg 2016;33:439-447 (Source: Digestive Surgery)
Source: Digestive Surgery - May 18, 2016 Category: Surgery Source Type: research

A Case of Survival: Myocardial Infarction and Ventricular Arrhythmia Induced by Severe Hydrogen Sulfide Poisoning
Most cases of acute hydrogen sulfide (H2S) poisoning in China are caused by sewage processing. With the rapid development of urbanization in China, H2S poisoning is showing an increasing trend. Here, we report a case of survival from severe H2S poisoning. A 40-year-old worker was found in the underground sewer lines. He was unresponsive with bilaterally dilated pupils and had poor oxygen saturation. After intubation, he was transferred to the intensive care unit. He developed respiratory failure, acute myocardial infarction, ventricular arrhythmia and left ventricular function impairment, requiring artificial ventilation w...
Source: Cardiology - May 18, 2016 Category: Cardiology Source Type: research

Different pattern of viral infections and clinical outcomes in patient with acute exacerbation of chronic obstructive pulmonary disease and chronic obstructive pulmonary disease with pneumonia
ConclusionsRespiratory viruses were commonly identified in both AE‐COPD and CP‐COPD, influenza virus and human coronavirus were the most common viruses identified in AE‐COPD and CP‐COPD patients, respectively. The mortality rates of only viral infection group was significantly lower than only bacterial infection or viral‐bacterial co‐infection group in CP‐COPD patients. This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)
Source: Journal of Medical Virology - May 18, 2016 Category: Virology Authors: Ho‐Cheol Kim, Sang‐Ho Choi, Jin‐Won Huh, Heungsup Sung, Sang Bum Hong, Chae‐Man Lim, Younsuck Koh Tags: Research Article Source Type: research

Middle East Respiratory Syndrome Coronavirus Transmission in Extended Family, Saudi Arabia, 2014
M. Arwady et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - May 18, 2016 Category: Infectious Diseases Source Type: research

Development of Medical Countermeasures to Middle East Respiratory Syndrome Coronavirus
T. M. Uyeki et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - May 18, 2016 Category: Infectious Diseases Source Type: research

Impaired bone healing in multitrauma patients is associated with altered leukocyte kinetics after major trauma
Okan W Bastian,1 Anne Kuijer,1 Leo Koenderman,2 Rebecca K Stellato,3 Wouter W van Solinge,4 Luke PH Leenen,1 Taco J Blokhuis1 1Department of Traumatology, 2Department of Respiratory Medicine, 3Department of Biostatistics and Research Support, Julius Center, 4Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, the Netherlands Abstract: Animal studies have shown that the systemic inflammatory response to major injury impairs bone regeneration. It remains unclear whether the systemic immune response contributes to impairment of fracture healing in multitrauma patients. It is well known...
Source: Journal of Inflammation Research - May 18, 2016 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research

Monitoring of Potential Safety Events and Vital Signs during Active Mobilization of Patients Undergoing Continuous Renal Replacement Therapy in a Medical Intensive Care Unit
Conclusions: This study showed that active mobilization PT can be performed safely in patients who are being treated with CRRT without a significant hemodynamic change. However, the development of potential safety events in patients with ECMO needs to be monitored carefully.Blood Purif 2016;42:83-90 (Source: Blood Purification)
Source: Blood Purification - May 18, 2016 Category: Hematology Source Type: research

Case report: a patient with pulmonary arterial hypertension transitioning from a PDE-5 inhibitor to Riociguat
We present here the case of a patient with pulmonary arterial hypertension and NYHA Class II symptoms who transitioned from PDE-5i therapy to riociguat. No protocol currently exists for transitioning between t... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 18, 2016 Category: Respiratory Medicine Authors: David S. Poch Source Type: research

CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development
Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1), the gene encoding YKL-40, and increased serum YKL-40 levels are associated with severe forms of asthma. It has never been addressed whether S... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 18, 2016 Category: Respiratory Medicine Authors: Jakob Usemann, Urs Frey, Ines Mack, Anne Schmidt, Olga Gorlanova, Martin Röösli, Dominik Hartl and Philipp Latzin Source Type: research