Respiratory Medicine Respiratory Medicine RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 11.

Health effects of natural spring waters: A protocol for systematic reviews with a regional case example
Discussion The protocol supports a review and comprehensive synthesis of the current evidence regarding the health effects of natural spring water, and can be adapted for reviews in other regions. From this evidence, recommendations regarding practice and future research can be made on the therapeutic role of spring water. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - November 21, 2015 Category: Complementary Medicine Source Type: research

Semi-Prone Position Can Influence Variability in Respiratory Rate of Premature Infants Using Nasal CPAP
To determine the effect of positions (supine, lateral, semiprone) on the physiological parameters (HR, RR, SpO2) of premature infants receiving NCPAP who were non-oxygen-dependent and non-BPD, and to identify significant clinical changes associated with these variables. (Source: Journal of Pediatric Nursing)
Source: Journal of Pediatric Nursing - November 21, 2015 Category: Nursing Authors: Ti Yin, Yeong-Seng Yuh, Jen-Jiuan Liaw, Yin-Yin Chen, Kai-Wei Katherine Wang Source Type: research

Analysis of the impact of limitation of medical treatment orders during unplanned transfers from sub-acute care to Emergency Departments
Conclusions Patients with LOMT had higher levels of comorbidity and were more acutely ill during their sub-acute care admission. Once transferred those with a LOMT had similar rates of cardiac arrest, MET activation and unplanned ICU admission, but higher mortality. (Source: Australasian Emergency Nursing Journal)
Source: Australasian Emergency Nursing Journal - November 21, 2015 Category: Nursing Source Type: research

Diuretics for transient tachypnoea of the newborn.
CONCLUSIONS: Diuretics cannot be recommended as treatment for transient tachypnoea of the newborn and it should not be used unless additional data become available. This finding suggests that either furosemide is not effective in promoting resorption of lung fluid, or factors other than delayed resorption of this fluid contribute to the pathogenesis of transient tachypnoea of the newborn. The question remains as to whether furosemide given to the infant (or even to the mother before caesarean section) might shorten the duration of the illness. As elective caesarean section continues at a high level, these two interventions...
Source: Cochrane Database of Systematic Reviews - November 21, 2015 Category: Journals (General) Authors: Kassab M, Khriesat WM, Anabrees J Tags: Cochrane Database Syst Rev Source Type: research

Interferon response of the cystic fibrosis bronchial epithelium to major and minor group rhinovirus infection
Rhinoviruses (RVs) are associated with exacerbations of cystic fibrosis (CF), asthma and COPD. There is growing evidence suggesting the involvement of the interferon (IFN) pathway in RV-associated morbidity in asthma and COPD. The mechanisms of RV-triggered exacerbations in CF are poorly understood. In a pilot study, we assessed the antiviral response of CF and healthy bronchial epithelial cells (BECs) to RV infection, we measured the levels of IFNs, pattern recognition receptors (PRRs) and IFN-stimulated genes (ISGs) upon infection with major and minor group RVs and poly(IC) stimulation. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - November 21, 2015 Category: Respiratory Medicine Authors: Aline Schögler, Andrea B. Stokes, Carmen Casaulta, Nicolas Regamey, Michael R. Edwards, Sebastian L. Johnston, Andreas Jung, Alexander Moeller, Thomas Geiser, Marco P. Alves Tags: Original Article Source Type: research

Sarcoidosis patient with lupus pernio and infliximab-induced myositis: Response to Acthar gel
We report a case of a patient with advanced sarcoidosis who developed a myositis type reaction to infliximab characterized by diffuse muscle achiness and weakness and marked elevations in serum creatinine phosphokinase (CPK) and aldolase. Manifestations of sarcoidosis and myositis improved after Acthar treatment. This is the first report of successful treatment with Acthar in a patient with advanced sarcoidosis with an autoimmune reaction to infliximab. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - November 21, 2015 Category: Respiratory Medicine Source Type: research

Chest X-rays for screening of paediatric PTB: child selection and standardised radiological criteria are key
This article is currently available as a free download on ingentaconnect (Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - November 21, 2015 Category: Respiratory Medicine Authors: Zar, Heather J.Andronikou, S. Tags: EDITORIALS Source Type: research

Oral Alimentation in Neonatal and Adult Populations Requiring High-Flow Oxygen via Nasal Cannula
Abstract Use of high-flow oxygen via nasal cannula (HFO2-NC) is increasingly common in intensive care unit (ICU) settings. Despite the critical interface between respiration and swallowing, and the high acuity of patients in ICUs, the impact of HFO2-NC on feeding and swallowing is unknown. The present prospective, single-center, cohort study investigated the impact of HFO2-NC use on oral alimentation in neonatal and adult ICU patients. Oral alimentation status was evaluated in 100 consecutive ICU inpatients (50 neonatal and 50 adult) requiring HFO2-NC. Participant characteristics, respiratory support, successful i...
Source: Dysphagia - November 21, 2015 Category: Speech Therapy Source Type: research

Surveillance for Severe Acute Respiratory Infections (SARI) in Southern Arizona, 2010-2014.
CONCLUSION: Influenza viruses were a frequent cause of SARI in hospitalized patients in Southern Arizona. Monitoring respiratory illness in border populations will help better understand the etiologies. Improving influenza vaccination coverage may help prevent some SARI cases. This article is protected by copyright. All rights reserved. PMID: 26590069 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - November 21, 2015 Category: Respiratory Medicine Authors: Wansaula Z, Olsen SJ, Casal M, Golenko C, Erhart LM, Kammerer P, Whitfield N, McCotter O Tags: Influenza Other Respir Viruses Source Type: research

Respiratory syncytial virus infection in macaques is not suppressed by intranasal sprays of pyrimidine biosynthesis inhibitors.
Abstract There is imperious need for efficient therapies against ubiquitous and life-threatening respiratory viruses, foremost among them being the human respiratory syncytial virus (hRSV). Several research groups who performed functional screens for broad-spectrum antivirals identified compounds targeting the de novo pyrimidine biosynthesis pathway. Despite their strong antiviral activity in vitro, whether such antimetabolites are effective in vivo remains highly controversial. Here, we evaluated two potent pyrimidine biosynthesis inhibitors developed in our laboratory, IPPA17-A04 and GAC50, in a model of mild hRS...
Source: Antiviral Research - November 21, 2015 Category: Virology Authors: Grandin C, Hourani ML, Janin Y, Dauzonne D, Munier-Lehmann H, Paturet A, Taborik F, Vabret A, Contamin H, Tangy F, Vidalain PO Tags: Antiviral Res Source Type: research

[Correspondence] Key donors to reinstate health funding to Zambia
In her World Report (Aug 8, p 519),1 Ann Danaiya Usher noted that key donors intend to reinstate health funding to Zambia 6 years after a corruption scandal that led them to withdraw funding. It is true that an immediate decline in health indicators—such as antenatal coverage, tuberculosis, malaria, and diarrhoeal and respiratory infections—was seen after the loss of funding. However, between 2007 and 2013, Zambia recorded huge reductions in maternal and child mortality—with under-5 mortality declining by 37% and maternal mortality by 33%—and improvements in several other service delivery indicators and health outc...
Source: LANCET - November 20, 2015 Category: Journals (General) Authors: Collins Chansa, Joel Negin Tags: Correspondence Source Type: research

[Perspectives] The experiences of a black doctor in the USA: a searing journey
During my first year as an internal medicine house officer working the overnight shift in the medical emergency room (ER) of the busiest public general hospital in Houston, TX, USA, I was assigned to care for a woman with a severe asthma exacerbation. After she had been stabilised and treated, I admitted her to the observation area of the ER. For the next 3–4 h, while scurrying around the ER caring for other patients, I would periodically pass by and wake her so as not to let her respiratory drive decline, which would lead to STAT intubation. (Source: LANCET)
Source: LANCET - November 20, 2015 Category: Journals (General) Authors: Wayne Riley Tags: Perspectives Source Type: research

Respiratory viruses associated with community-acquired pneumonia in children: matched case-control study
Respiratory viruses are known to cause a significant number of cases of community acquired pneumonia (CAP), the worldwide leading cause of death in children up to 5 years. Vaccination has successfully decreased cases of bacterial CAP, suggesting the increasing importance or understanding viral CAP in children. (Source: The Journal of Emergency Medicine)
Source: The Journal of Emergency Medicine - November 20, 2015 Category: Emergency Medicine Authors: Lena Ning Tags: Abstract Source Type: research

COPD: Novel therapeutics and management strategies - SMi's 7th Annual Conference (October 19-20, 2015 - London, UK).
This report covers highlights from the 2-day meeting. PMID: 26583304 [PubMed - as supplied by publisher] (Source: Drugs of Today)
Source: Drugs of Today - November 20, 2015 Category: Drugs & Pharmacology Tags: Drugs Today (Barc) Source Type: research

Primary Pulmonary Angiosarcoma Presenting with Hemoptysis and Ground-Glass Opacity: A Case Report and Literature Review.
Abstract Angiosarcoma originates from the vascular endothelium and accounts for only 1-2% of all sarcomatous malignancies. The skin is one of the most common primary sites. However, primary pulmonary angiosarcoma is rare, and only 31 cases of primary pulmonary angiosarcoma have been reported. A 79-year-old Japanese female developed bloody sputum, and chest X-ray and chest computed tomography (CT) showed consolidation with ground-glass opacity (GGO) on the right middle and lower lung fields. The bronchoscopic findings demonstrated bleeding from the right B(4) and B(5), and bronchial arterial embolization was subsequ...
Source: The Tohoku Journal of Experimental Medicine - November 20, 2015 Category: Research Authors: Shimabukuro I, Yatera K, Noguchi S, Kawanami Y, Iwanami T, Nishida C, Yamasaki K, Kawanami T, Ishimoto H, So T, Uramoto H, Yoshii C, Tanaka F, Mukae H Tags: Tohoku J Exp Med Source Type: research

S.T.A.R.T.T. plus: addition of prehospital personnel to a national multidisciplinary crisis resource management trauma team training course.
Abstract SUMMARY: The Simulated Trauma and Resuscitation Team Training (S.T.A.R.T.T.) course is a unique multidisciplinary trauma team training course deliberately designed to address the common crisis resource management (CRM) skills of trauma team members. Moreover, the curriculum has been updated to also target the specific learning needs of individual participating professionals: physicians, nurses and respiratory therapists. This commentary outlines further modifications to the course curriculum in order to address the needs of a relatively undertargeted group: prehospital personnel (i.e., emergency medical se...
Source: Canadian Journal of Surgery - November 20, 2015 Category: Surgery Authors: Gillman LM, Martin D, Engels PT, Brindley P, Widder S, French C Tags: Can J Surg Source Type: research

Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study.
CONCLUSIONS: The ADEPT study successfully enrolled asthmatics across a spectrum of severity and non-atopic controls. Clinical characteristics were related to asthma severity and in general asthma characteristics e.g. lung function, were stable over 12 months. Use of the ADEPT data should prove useful in defining biological phenotypes to facilitate personalized therapeutic approaches. PMID: 26576744 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - November 20, 2015 Category: Respiratory Medicine Authors: Silkoff PE, Strambu I, Laviolette M, Singh D, FitzGerald JM, Lam S, Kelsen S, Eich A, Ludwig-Sengpiel A, Hupp GC, Backer V, Porsbjerg C, Girodet PO, Berger P, Leigh R, Kline JN, Dransfield M, Calhoun W, Hussaini A, Khatri S, Chanez P, Susulic VS, Barnatha Tags: Respir Res Source Type: research

Characteristics, disease burden and costs of COPD patients in the two years following initiation of long-acting bronchodilators in UK primary care.
CONCLUSION: Cost and symptomatic burden of COPD was high among patients initiating maintenance treatment, including patients adherent with their initial treatment. General practitioner interactions were the primary driver of costs. Further, real world studies are required to address unmet needs and optimize treatment pathways to improve COPD symptom burden and outcomes. PMID: 26572740 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - November 20, 2015 Category: Respiratory Medicine Authors: Punekar YS, Landis SH, Wurst K, Le H Tags: Respir Res Source Type: research

Fluid Management With a Simplified Conservative Protocol for the Acute Respiratory Distress Syndrome
No abstract available (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - November 20, 2015 Category: Anesthesiology Tags: Critical Care Source Type: research

Recent Patents of Complementary and Alternative Medicine for Allergic Rhinitis.
Authors: Hon KL, Fung CK, Leung AK, Lam HS, Lee SL Abstract Allergic rhinitis (AR) is a common respiratory disease affecting both adults and children worldwide. Affected patients may experience nasal congestion/stuffiness, rhinorrhea (anterior and/or posterior), nasal/nasopharyngeal itching and sneezing. Allergen avoidance is the principal step in the management. Nasal saline irrigation to remove allergen (s) in the nose is a useful adjunctive therapy in the management of moderate to severe AR. Symptomatic relief and improved quality of life may be achieved in the majority of patients with appropriate pharmacothera...
Source: Recent Patents on Inflammation and Allergy Drug Discovery - November 20, 2015 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

House dust mite‐specific IgA2 is associated with protection against eczema in allergic patients
This article is protected by copyright. All rights reserved. (Source: Allergy)
Source: Allergy - November 20, 2015 Category: Allergy & Immunology Authors: Gerco den Hartog, R. J. Joost Neerven, Johan D. Boot, Ad P. H. Jansen, Huub F. J. Savelkoul Tags: Brief Communication Source Type: research

[Deaths in a Tunisian psychiatric hospital: an eleven-year retrospective study].
CONCLUSION: Identifying risk factors for deaths in psychiatric hospitals highlights needed changes in psychiatric management strategies taking into account the patient's characteristics as well as the drugs' safety profile. Further studies with larger samples are needed to better highlight risk factors for premature death in psychiatric inpatients. Identifying such risk factors is necessary to develop efficient preventive strategies. PMID: 25132014 [PubMed - indexed for MEDLINE] (Source: L Encephale)
Source: L Encephale - November 20, 2015 Category: Psychiatry Tags: Encephale Source Type: research

Feasibility Study of Respiratory Motion Modeling Based Correction for MRI-Guided Intracardiac Interventional Procedures
Conclusion: The feasibility of a respiratory motion model-based correction framework has been successfully demonstrated. Significance: The improvement in ablation accuracy may lead to significant improvements in success rate and patient outcomes for MRI-guided intracardiac procedures. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - November 20, 2015 Category: Biomedical Engineering Source Type: research

A Single-Center Analysis of Methylprednisolone Use during Pediatric Cardiopulmonary Bypass.
Authors: Dreher M, Glatz AC, Kennedy A, Rosenthal T, Gaynor JW Abstract Cardiac surgery with the use of cardiopulmonary bypass (CPB) is known to induce an inflammatory response in patients. This response may be even more pronounced in pediatric patients given their small body size compared to adults. Several interventions have been instituted in an effort to attenuate this response, including the use of corticosteroids in the pump prime. However, the clinical effectiveness and potential harmful effects of steroid use have been the source of recent debate. Therefore, our institution made the decision to evaluate the...
Source: Journal of Extra-Corporeal Technology - November 20, 2015 Category: Cardiovascular & Thoracic Surgery Tags: J Extra Corpor Technol Source Type: research

Ruptured spinal arteriovenous malformation: Presenting as stunned myocardium and neurogenic shock.
CONCLUSIONS: Spinal AVM rupture can present as neurogenic shock, stunned myocardium, and pulmonary edema. Early recognition of AVM rupture and prompt surgical intervention, as well as aggressive treatment of shock, may enhance recovery and decrease the long-term morbidity. PMID: 26539315 [PubMed] (Source: Surgical Neurology International)
Source: Surgical Neurology International - November 20, 2015 Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

Phrenic Nerve Stimulation: Technology and Clinical Applications.
Authors: Abdunnur SV, Kim DH Abstract Phrenic nerve stimulation is a technique used to reanimate the diaphragm of patients with central nervous system etiologies of respiratory insufficiency. Current clinical indications include congenital central hypoventilation syndrome, spinal cord injury above C4, brain stem injury, and idiopathic severe sleep apnea. Presurgical evaluation ensures proper patient selection by validating the intact circuit from the phrenic nerve through alveolar oxygenation. The procedure involves placing leads around the phrenic nerves bilaterally and attaching these leads to radio receivers in ...
Source: Progress in Neurological Surgery - November 20, 2015 Category: Neurosurgery Tags: Prog Neurol Surg Source Type: research

[Diseases of the respiratory system as causes of sudden death].
Authors: Luvoni R, Ritucci A PMID: 5602519 [PubMed - indexed for MEDLINE] (Source: Minerva Medicolegale)
Source: Minerva Medicolegale - November 20, 2015 Category: Forensic Medicine Tags: Minerva Medicoleg Source Type: research

Human Linguatulosis Caused by Linguatula serrata in the City of Kerman, South-eastern Iran- Case Report.
This study reports a case of human linguatulosis caused by Linguatula serrata in the city of Kerman, South-eastern Iran. A woman suffering from upper respiratory symptoms is presented. The patient consumed raw liver of sheep who was admitted to the Afzalipour University Hospital in Kerman for the symptoms of upper respiratory tract. In microscopic examination of the nasopharyngeal discharge, L. serrata was detected. This report has future medical implication in precise diagnosis of L. serrata in patients with complaints of nasopharyngeal symptoms. PMID: 25848397 [PubMed] (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - November 20, 2015 Category: Parasitology Tags: Iran J Parasitol Source Type: research

Fentanyl-induced hyperalgesia in acute pain management.
Authors: Lyons PJ, Rivosecchi RM, Nery JP, Kane-Gill SL Abstract There are safety concerns with the use of fentanyl, including respiratory depression, nausea, constipation, and possibly opioid-induced hyperalgesia (OIH). The purpose of this review is to evaluate the occurrence and significance of opioid-induced hyperalgesia (OIH) after acute fentanyl exposure. A literature search was conducted from October 1995 through January 2015 using MEDLINE, Embase, and Scopus with the terms hyperalgesia, fentanyl, pronociceptive, acute tolerance, and acute. Published articles evaluating the adverse effects of fentanyl during ...
Source: Journal of Pain and Palliative Care Pharmacotherapy - November 20, 2015 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

Discontinuance of life sustaining treatment utilizing ketamine for symptom management.
We present the case of an otherwise healthy 21-year-old female who developed severe respiratory failure following a minor procedure requiring ECMO and bi-level ventilation. During her protracted ICU course, she had significant difficulties with agitation and was titrated to the following regimen: hydromorphone 30 mg/hour, fentanyl 200 mcg/hour, dexmedetomidine 1.5 mcg/kg/hour, propofol at 70 mcg/kg/min, and midazolam at 20 mg/hour. We were consulted to assist in withdrawal of life prolonging measures at the family's request and given high doses of commonly used opioid and sedative medications successfully utilized methadon...
Source: Journal of Pain and Palliative Care Pharmacotherapy - November 20, 2015 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

The cost of opioid-related adverse drug events.
Authors: Kane-Gill SL, Rubin EC, Smithburger PL, Buckley MS, Dasta JF Abstract Opioids are the cornerstone of pain management; however, their use is associated with a variety of adverse drug events (ADEs) ranging from nausea and vomiting to urinary retention and respiratory depression. The purpose of this review is to describe the frequency and cost associated with different types of opioid-related ADEs to better understand their economic impact. A search of studies published in journals from 1946 to December, 2013, was conducted using MEDLINE and EMBASE. A total of 20 articles were reviewed. Data reflect a substan...
Source: Journal of Pain and Palliative Care Pharmacotherapy - November 20, 2015 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

The big picture: A case report of antibody mediated rejection and treatment after lung transplantation illustrating the need to correlate laboratory findings with clinical status.
We report the case of a patient who developed respiratory failure in the presence of de novo donor-specific antibody (DSA) two years after lung transplantation, following recurrent acute cellular rejection. The patient underwent salvage therapy with plasma exchange, intravenous immunoglobulins, and proteasome inhibitor carfilzomib (CFZ). DSA was detected prior to admission for antibody-mediated rejection by single antigen bead Luminex (SAB) testing and indicated the presence of a DQ3 pattern (DQ7, DQ8, and DQ9). The patient initially responded to CFZ-based treatment with a decline in DQ3-DSA strengths, but DQ7-DSA persiste...
Source: Clinical Transplants - November 20, 2015 Category: Transplant Surgery Tags: Clin Transpl Source Type: research

A novel device to stretch multiple tissue samples with variable patterns: application for mRNA regulation in tissue-engineered constructs.
Authors: Imsirovic J, Derricks K, Buczek-Thomas JA, Rich CB, Nugent MA, Suki B Abstract A broad range of cells are subjected to irregular time varying mechanical stimuli within the body, particularly in the respiratory and circulatory systems. Mechanical stretch is an important factor in determining cell function; however, the effects of variable stretch remain unexplored. In order to investigate the effects of variable stretch, we designed, built and tested a uniaxial stretching device that can stretch three-dimensional tissue constructs while varying the strain amplitude from cycle to cycle. The device is the fir...
Source: Biomatter - November 20, 2015 Category: Biotechnology Tags: Biomatter Source Type: research

Hypoxic Episodes in Bronchopulmonary Dysplasia
Hypoxic episodes are troublesome components of bronchopulmonary dysplasia (BPD) in preterm infants. Immature respiratory control seems to be the major contributor, superimposed on abnormal respiratory function. Relatively short respiratory pauses may precipitate desaturation and bradycardia. This population is predisposed to pulmonary hypertension; it is likely that pulmonary vasoconstriction also plays a role. The natural history has been well-characterized in the preterm population at risk for BPD; however, the consequences are less clear. Proposed associations of intermittent hypoxia include retinopathy of prematurity, ...
Source: Clinics in Perinatology - November 20, 2015 Category: Perinatology & Neonatology Authors: Richard J. Martin, Juliann M. Di Fiore, Michele C. Walsh Source Type: research

Airway Disease and Management in Bronchopulmonary Dysplasia
This article presents an overview of the diagnosis and management of airway problems encountered in infants with severe bronchopulmonary dysplasia (BPD). Respiratory failure in premature infants develops as a result of parenchymal and airway diseases. The survival of increasingly premature infants and the ventilatory support required by premature lungs may result in airway disease. The management of respiratory failure depends on whether it is primarily caused by parenchymal versus airway diseases. Continuous airway pressure early in the neonatal period has favorably changed the incidence of BPD. This article discusses the...
Source: Clinics in Perinatology - November 20, 2015 Category: Perinatology & Neonatology Authors: Raouf S. Amin, Michael J. Rutter Source Type: research

Identification of hub genes of pneumocyte senescence induced by thoracic irradiation using weighted gene co‑expression network analysis.
Authors: Xing Y, Zhang J, Lu L, Li D, Wang Y, Huang S, Li C, Zhang Z, Li J, Meng A Abstract Irradiation commonly causes pneumocyte senescence, which may lead to severe fatal lung injury characterized by pulmonary dysfunction and respiratory failure. However, the molecular mechanism underlying the induction of pneumocyte senescence by irradiation remains to be elucidated. In the present study, weighted gene co‑expression network analysis (WGCNA) was used to screen for differentially expressed genes, and to identify the hub genes and gene modules, which may be critical for senescence. A total of 2,916 differential...
Source: Molecular Medicine Reports - November 20, 2015 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Clinical profile and factors associated with mortality in hospitalized patients with HIV/AIDS: a retrospective analysis from Tripoli Medical Centre, Libya, 2013.
In this study, late presentation with severe immunosuppression was common, and was associated with significant in-hospital mortality. PMID: 26450860 [PubMed - in process] (Source: Eastern Mediterranean Health Journal)
Source: Eastern Mediterranean Health Journal - November 20, 2015 Category: Middle East Health Tags: East Mediterr Health J Source Type: research

Herbal and nutritional supplement use among college students in Qatar.
This study aimed to examine the use of supplements by college students in Qatar and to elucidate users' views about them. A total of 419 college students completed a self-administered questionnaire. Almost half of the respondents (49.6%) had used supplements (ever users), with 32.7% reporting using them in the previous 6 months (current users). Of the latter, 27.7% had used herbal supplements, 56.2% vitamins and minerals and 56.9% non-vitamin, non-mineral, non-herbal supplements. Many participants considered supplements to be safer and more effective than conventional medicines. Supplements were preferred over conventional...
Source: Eastern Mediterranean Health Journal - November 20, 2015 Category: Middle East Health Tags: East Mediterr Health J Source Type: research

Effect of airway acidosis and alkalosis on airway vascular smooth muscle responsiveness to albuterol.
CONCLUSIONS: Albuterol responsiveness in the airway as assessed by ΔQ̇aw is pH sensitive. The breathing maneuver associated with decreased and increased EBC pH both resulted in a decreased responsiveness independent of the level of ventilation. These findings suggest an attenuated response to hydrophilic β2-adrenergic agonists during airway disease exacerbations associated with changes in pH. TRIAL REGISTRATION: Registered at NCT01216748 . PMID: 25889594 [PubMed - in process] (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - November 20, 2015 Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research

Evaluation of lung recovery after static administration of three different perfluorocarbons in pigs.
CONCLUSIONS: Of the three tested perfluorocarbons, PFOC offered the best tolerance in terms of lung function, gas exchanges and residuum in the lung. PFOC was rapidly cleared from the lungs and virtually disappeared after 4 days whereas PFOB persisted at significant levels and led to foam macrophage infiltration. PFOC could be relevant for short term total liquid ventilation with a rapid weaning. PMID: 25253660 [PubMed - indexed for MEDLINE] (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - November 20, 2015 Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research

Pharmacoepidemiology of common colds and upper respiratory tract infections in children and adolescents in Germany.
CONCLUSIONS: The use of medicines to treat CCs or URTIs is widespread among children and adolescents in Germany. Thus, longitudinal studies should investigate the risks associated with this drug use. Differences in socio-demographic variables regarding exposure to antibiotic use indicate that there could be an implausible prescribing behavior among physicians in Germany. PMID: 25106446 [PubMed - indexed for MEDLINE] (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - November 20, 2015 Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research

Medication errors related to transdermal opioid patches: lessons from a regional incident reporting system.
CONCLUSIONS: Of the reported MEs related to transdermal fentanyl and buprenorphine, most occurred during administration. Improved routines to ascertain correct and timely administration and educational interventions to reduce MEs for these drugs are warranted. PMID: 24912424 [PubMed - indexed for MEDLINE] (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - November 20, 2015 Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research

Knowledge and beliefs on antimicrobial resistance among physicians and nurses in hospitals in Amhara Region, Ethiopia.
CONCLUSION: Majority of physicians and nurses lack up to-date knowledge on AMR. Unavailability of local antibiogram data, self-prescription by patients and poor awareness on AMR are areas of interventions for prevention and control of AMR. PMID: 24887310 [PubMed - indexed for MEDLINE] (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - November 20, 2015 Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research

Unplanned medication discontinuation as a potential pharmacovigilance signal: a nested young person cohort study.
CONCLUSIONS: Identification of unplanned medication discontinuation using large primary care datasets may be a useful tool for pharmacovigilance signal generation and detection of potential ADRs in children and young people. PMID: 24594374 [PubMed - indexed for MEDLINE] (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - November 20, 2015 Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research

Vertebral Osteomyelitis in Pregnancy from a Methicillin-resistant Staphylococcus Aureus Vulvar Abscess. A Case Report.
CONCLUSION: Osteomyelitis in pregnancy is a rare complication and a challenging diagnosis that requires a high index of suspicion. The treatment of osteomyelitis in pregnancy versus nonpregnancy is the same. This case is unique because this pregnant patient developed osteomyelitis secondary to a vulvar abscess. PMID: 26380498 [PubMed - indexed for MEDLINE] (Source: Journal of Reproductive Medicine)
Source: Journal of Reproductive Medicine - November 20, 2015 Category: Reproduction Medicine Tags: J Reprod Med Source Type: research

Airway pressure release ventilation and respiratory failure during pregnancy. A report of three cases.
CONCLUSION: Airway pressure release ventilation may be an important option as a ventilatory mode for management of maternal respiratory failure during pregnancy. PMID: 25745754 [PubMed - indexed for MEDLINE] (Source: Journal of Reproductive Medicine)
Source: Journal of Reproductive Medicine - November 20, 2015 Category: Reproduction Medicine Tags: J Reprod Med Source Type: research