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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 11.

Short-term effects of particulate matter on mortality during forest fires in Southern Europe: results of the MED-PARTICLES Project
Conclusions Smoke is associated with increased cardiovascular mortality in urban residents, and PM10 on smoky days has a larger effect on cardiovascular and respiratory mortality than on other days. (Source: Occupational and Environmental Medicine)
Source: Occupational and Environmental Medicine - April 14, 2015 Category: Occupational Health Authors: Faustini, A., Alessandrini, E. R., Pey, J., Perez, N., Samoli, E., Querol, X., Cadum, E., Perrino, C., Ostro, B., Ranzi, A., Sunyer, J., Stafoggia, M., Forastiere, F., the MED-PARTICLES study group, Angelini, Berti, Bisanti, Catrambone, Chiusolo, Davoli, Tags: Environment Source Type: research

Extended follow-up of lung cancer and non-malignant respiratory disease mortality among California diatomaceous earth workers
Conclusions The risk of lung cancer and NMRD mortality remained elevated, although generally non-significant, and exposure-response trends with cumulative crystalline silica persisted on extended follow-up of this cohort. The findings support a generally consistently observed aetiological relation between crystalline silica and lung cancer. (Source: Occupational and Environmental Medicine)
Source: Occupational and Environmental Medicine - April 14, 2015 Category: Occupational Health Authors: Gallagher, L. G., Park, R. M., Checkoway, H. Tags: Asbestos, Other exposures Workplace Source Type: research

Occupational asthma after exposure to ortho-phthalaldehyde (OPA)
We describe the case of a 55-year-old woman who consulted at the emergency department with dyspnoea, wheezing, conjunctival redness and low peak expiratory flow. She had been promoted to the endoscopic sterilisation service of a regional hospital 2 months earlier, where OPA (Cidex OPA) was used for disinfection of endoscopes. Symptoms developed after 3 weeks of exposure but subsided during the evening and disappeared on weekends. She was known for hypertension and had quit smoking 20 years earlier (15 pack-years of cigarettes). She had no personal or family history of asthma. Chest radiograph and blood work ...
Source: Occupational and Environmental Medicine - April 14, 2015 Category: Occupational Health Authors: Robitaille, C., Boulet, L.-P. Tags: PostScript Source Type: research

Indoor airborne microbial burden and risk of acute respiratory infections among children under five in Ibadan, Nigeria
This study was designed to determine the burden of airborne microbes in indoor environment that predispose under-five children to acute respiratory infections. A prospective case–control design was employed for this study. Two hundred and twenty under-five children each with acute respiratory infection (cases) and without acute respiratory infection (controls) were selected from children visiting Oni-memorial Children Hospital and University College Hospital, Ibadan. A follow-up of 66 consented cases and controls each was carried out to assess the burden of indoor airborne microbes using a non-volumetric method, and ...
Source: Indoor and Built Environment - April 14, 2015 Category: Occupational Health Authors: Ana, G. R., Fakunle, G. A., Ogunjobi, A. A. Tags: Original Papers Source Type: research

High-flow nasal cannula oxygen during endotracheal intubation in hypoxemic patients: a randomized controlled clinical trial
Conclusions Compared to HFFM, HFNC as a preoxygenation device did not reduce the lowest level of desaturation. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - April 14, 2015 Category: Intensive Care Source Type: research

IJERPH, Vol. 12, Pages 4170-4184: Incorporation of Spatial Interactions in Location Networks to Identify Critical Geo-Referenced Routes for Assessing Disease Control Measures on a Large-Scale Campus
Respiratory diseases mainly spread through interpersonal contact. Class suspension is the most direct strategy to prevent the spread of disease through elementary or secondary schools by blocking the contact network. However, as university students usually attend courses in different buildings, the daily contact patterns on a university campus are complicated, and once disease clusters have occurred, suspending classes is far from an efficient strategy to control disease spread. The purpose of this study is to propose a methodological framework for generating campus location networks from a routine administration database,...
Source: International Journal of Environmental Research and Public Health - April 14, 2015 Category: Environmental Health Authors: Tzai-Hung WenWei Chin Tags: Article Source Type: research

Current methods for capsular typing of Streptococcus pneumoniae
Publication date: June 2015 Source:Journal of Microbiological Methods, Volume 113 Author(s): Elita Jauneikaite , Anna S. Tocheva , Johanna M.C. Jefferies , Rebecca A. Gladstone , Saul N. Faust , Myron Christodoulides , Martin L. Hibberd , Stuart C. Clarke Streptococcus pneumoniae is a major respiratory tract pathogen causing pneumococcal disease mainly in children aged less than five years and in the elderly. Ninety-eight different capsular types (serotypes) of pneumococci have been reported, but pneumococcal conjugate vaccines (PCV) include polysaccharide antigens against only 7, 10 or 13 serotypes. It is therefore impo...
Source: Journal of Microbiological Methods - April 14, 2015 Category: Microbiology Source Type: research

Continuous Positive Airway Pressure treatment of premature infants; application of a computerized decision support system
The predictions of a computerized decision-support system (CDSS) are compared to clinical data obtained from a group of premature infants. The infants were suffering from respiratory distress syndrome (RDS) and were treated by Continuous Positive Airway Pressure (CPAP) therapy. The predictions of the CDSS are found to be in general agreement with clinical measurements. The CDSS is also used to determine the effect of low level oxygen treatment on arterial oxygen pressure if the infant's oxygenation is low despite CPAP therapy. (Source: Computers in Biology and Medicine)
Source: Computers in Biology and Medicine - April 14, 2015 Category: Bioinformatics Authors: Fleur T. Tehrani, Soraya Abbasi Source Type: research

Drug Inhalation Devices and Delivery Systems
Inhalation drug therapy is the primary way to deliver medication locally to the lungs because of its speed, effectiveness, and minimal systemic side effects. Although once used to extensively treat respiratory conditions such as asthma, recently, inhalation therapy has been acknowledged as an effective route to systemically deliver drugs for other conditions. The development of novel inhalers has improved performance, efficacy, and patient adherence. This discussion is focused on available inhalation devices including new options that enhance drug delivery. (Source: The Journal for Nurse Practitioners)
Source: The Journal for Nurse Practitioners - April 14, 2015 Category: Nursing Authors: Shalonda D. Williams Tags: Prescription Pad Source Type: research

Feasibility study: Assessing the influence of macronutrient intakes on preterm body composition, using air displacement plethysmography
ConclusionPreterm infants can be measured in the PEA POD as early as 31 weeks corrected gestational age and the method appears sufficiently sensitive to detect influences of macronutrient intake on changes in BC. (Source: Journal of Paediatrics and Child Health)
Source: Journal of Paediatrics and Child Health - April 14, 2015 Category: Pediatrics Authors: Gemma McLeod, Karen Simmer, Jill Sherriff, Elizabeth Nathan, Donna Geddes, Peter Hartmann Tags: Original Article Source Type: research

Clinical audit results in earlier nutritional intervention in malnourished children with cystic fibrosis with improved outcome
ConclusionEarlier referral of patients in the recent cohort resulted in sustained improvements in weight‐for‐age and lung function. Survival at 2 years post‐procedure was significantly improved. This study confirms the value of clinical audits and subsequent re‐evaluation of clinical services. (Source: Journal of Paediatrics and Child Health)
Source: Journal of Paediatrics and Child Health - April 14, 2015 Category: Pediatrics Authors: Oren Ledder, Mark R Oliver, Ralf G Heine, Joanne Graham, Evelyn Volders, Philip J Robinson Tags: Original Article Source Type: research

TTF‐1 and napsin A on cell blocks and supernatants of pleural fluids for labeling malignant effusions
In this retrospective study of 80 pleural effusions, the combination of thyroid transcription factor 1 (TTF‐1) and napsin A immunostaining on fluid cell blocks was positive in 80% of lung adenocarcinomas. Although measuring TTF‐1 pleural fluid concentrations was of no value, quantification of napsin A levels allowed the identification of one third of the double‐negative stained lung adenocarcinomas, with an overall accuracy similar to classical tumour markers for malignant–benign discrimination (sensitivity 40%, specificity 100%). (Source: Respirology)
Source: Respirology - April 14, 2015 Category: Respiratory Medicine Authors: José M. Porcel, Rosa Palma, Silvia Bielsa, Aureli Esquerda, Sonia Gatius, Xavier Matias‐Guiu, Antonieta Salud Tags: Scientific Letter Source Type: research

Hiatal hernias are correlated with increased severity of non‐cystic fibrosis bronchiectasis
ConclusionsHH+ was associated with worse disease severity in NCFB patients, characterized by decreased lung function, increased extent and severity of radiological disease, and increased composite disease severity scores. (Source: Respirology)
Source: Respirology - April 14, 2015 Category: Respiratory Medicine Authors: Melissa Jane McDonnell, Mohammad Ahmed, Jeeban Das, Chris Ward, Matshediso Mokoka, David P. Breen, Anthony O'Regan, John J. Gilmartin, John Bruzzi, Robert M. Rutherford Tags: Original Article Source Type: research

Phenotypic, Functional and Plasticity Features of Classical and Alternatively Activated Human Macrophages.
Abstract Macrophages are dynamic cells that mature under the influence of signals from the local microenvironment into either classically (M1) or alternatively (M2) activated macrophages with specific functional and phenotypic properties. While the phenotypic identification of M1 and M2 macrophages is well established in mice, this is less clear for human macrophages. In addition, the persistence and reversibility of polarized human phenotypes is not well established. Human peripheral blood monocytes were differentiated into macrophages (M0) and then polarized to M1 and M2 phenotypes using LPS/IFN-g and IL-4/IL-13,...
Source: American Journal of Respiratory Cell and Molecular Biology - April 14, 2015 Category: Molecular Biology Authors: Tarique AA, Logan J, Thomas E, Holt PG, Sly PD, Fantino E Tags: Am J Respir Cell Mol Biol Source Type: research

A Numerical Study of Water Loss Rate Distributions in MDCT-Based Human Airway Models.
Abstract Both three-dimensional (3D) and one-dimensional (1D) computational fluid dynamics methods are applied to study regional water loss in three multi-detector row computed-tomography-based human airway models at the minute ventilations of 6, 15 and 30 L/min. The overall water losses predicted by both 3D and 1D models in the entire respiratory tract agree with available experimental measurements. However, 3D and 1D models reveal different regional water loss rate distributions due to the 3D secondary flows formed at bifurcations. The secondary flows cause local skewed temperature and humidity distributions on i...
Source: Annals of Biomedical Engineering - April 14, 2015 Category: Biomedical Engineering Authors: Wu D, Miyawaki S, Tawhai MH, Hoffman EA, Lin CL Tags: Ann Biomed Eng Source Type: research

The impact of two different inspiratory to expiratory ratios (1:1 and 1:2) on respiratory mechanics and oxygenation during volume-controlled ventilation in robot-assisted laparoscopic radical prostatectomy: a randomized controlled trial.
CONCLUSIONS: Compared with an I:E ratio of 1:2, a ratio of 1:1 lowered Ppeak without reducing CO during pneumoperitoneum and steep Trendelenburg positioning. Nevertheless, our results did not support its use solely for improving oxygenation. This trial was registered at http://clinicaltrials.gov/ (NCT01892449). PMID: 25869025 [PubMed - as supplied by publisher] (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - April 14, 2015 Category: Anesthesiology Authors: Kim MS, Kim NY, Lee KY, Choi YD, Hong JH, Bai SJ Tags: Can J Anaesth Source Type: research

Use of non‐pharmaceutical interventions to reduce the transmission of influenza in adults: A systematic review
Abstract During seasonal influenza epidemics and pandemics, virus transmission causes significant public health concern. Reduction of viral transmission by non‐pharmaceutical interventions (NPI) has a significant appeal and is often recommended. However, the efficacy of such interventions is unclear. A systematic literature review was undertaken to identify and evaluate the published literature on NPI efficacy to prevent human transmission of influenza virus in adults. Reviewers assessed the quality of eligible studies utilizing the Critical Appraisal Skills Programme for bias and the Scottish Intercollegiate Guidelines ...
Source: Respirology - April 14, 2015 Category: Respiratory Medicine Authors: Sheree M.S. Smith, Sandra Sonego, Gwenyth R. Wallen, Grant Waterer, Allen C. Cheng, Philip Thompson Tags: Review Source Type: research

Induction of MUC5AC mucin expression by histamine through the activation of its core promoter region.
CONCLUSION: This study provides evidence that histamine induced MUC5AC mRNA expression through the activation of the core region of its promoter. It may also help in approaching new therapeutic strategies in airway mucins hypersecretory diseases. OBJECTIVE: Mucin hypersecretion characterizes several respiratory diseases. Production of MUC5AC, a major gel forming mucin secreted by airway epithelia, can be induced by various inflammatory mediators. Histamine is associated with MUC5AC up-regulation during the early phase of allergic respiratory diseases. The goal of the present study was to identify whether histamine may ...
Source: Acta Oto-Laryngologica - April 14, 2015 Category: ENT & OMF Authors: Xu F, Zhang L, Gao J, Wang D Tags: Acta Otolaryngol Source Type: research

Year in Review 2014: Asthma.
Abstract Asthma continues to be recognized as a well-known respiratory disease requiring complex management. Asthma is assessed and treated by clinicians across the continuum. The interest in evidence-based recommendations for diagnosis, treatment, and long-term management is ongoing and essential for aligning clinical practice with its changes. The purpose of this review is to provide updates from recent literature on asthma for clinicians. PMID: 25873743 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - April 14, 2015 Category: Respiratory Medicine Authors: Deakins KM Tags: Respir Care Source Type: research

Effect of CPAP on Endothelial Function in Subjects With Obstructive Sleep Apnea: A Meta-Analysis.
Abstract Obstructive sleep apnea (OSA) is related to endothelial dysfunction. CPAP is the first-line treatment for OSA. We conducted a meta-analysis to evaluate the effect of CPAP on endothelial function in subjects with OSA. The PubMed, Embase, and Cochrane Library databases were searched. The overall effects were measured by the weighted mean difference with a 95% CI. Subgroup and meta-regression analyses were used to explore the sources of between-study heterogeneity. Eleven studies were eligible for the meta-analysis. A random-effects model revealed that CPAP significantly improved endothelial function as asses...
Source: Respiratory Care - April 14, 2015 Category: Respiratory Medicine Authors: Xu H, Wang Y, Guan J, Yi H, Yin S Tags: Respir Care Source Type: research

Pulmonary-Specific Intermountain Risk Score Predicts All-Cause Mortality via Spirometry, the Red Cell Distribution Width, and Other Laboratory Parameters.
CONCLUSIONS: Pulmonary-specific IMRS and pulmonary-specific basic metabolic profile risk score provided excellent discrimination of mortality among pulmonary subjects. These risk stratification tools combine familiar, relatively inexpensive, commonly-measured, standardized laboratory parameters with spirometry data. They may be electronically calculated and delivered at the point of care, providing meaningful risk information to assist clinicians in patient evaluations. PMID: 25873741 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - April 14, 2015 Category: Respiratory Medicine Authors: Horne BD, Hegewald M, Muhlestein JB, May HT, Huggins EJ, Bair TL, Anderson JL Tags: Respir Care Source Type: research

Prescribed therapy for asthma: therapeutic ratios and outcomes
Background: Inhaled corticosteroids (ICS) are the cornerstone of asthma therapy. The ICS-to-total-asthma-medication ratios, calculated from claims data, indicate potentially risky disease management in asthma. Our aim was to assess the utility of ICS-to-total-asthma-medication ratios from primary care electronic medical records (EMRs) in detecting patients at risk of asthma exacerbation, as approached by prescription of oral corticosteroids and/or antibiotics. Methods: Retrospective cohort studies were identified, using the Health Improvement Network general practice database (THIN, United Kingdom) and the Cegedim Longitud...
Source: BMC Family Practice - April 14, 2015 Category: Primary Care Authors: Laurent LaforestIdlir LicajGilles DevouassouxIrene ErikssonPascal CailletGérard ChatteManon BelhassenEric Van Ganse Source Type: research

Lessons learned from the application of BEES-C: Systematic assessment of study quality of epidemiologic research on BPA, neurodevelopment, and respiratory health.
Abstract Epidemiologic studies evaluating associations between biomarkers of exposure to short-lived chemicals and health endpoints in humans face special challenges. Perhaps the most critical challenges are the need to determine the type and optimal number of samples, and the proper timing of specimen collection. Further, as many short-lived chemicals are ubiquitous in the environment, utmost care is required to avoid sample contamination. A separate set of challenges is associated with appropriate interpretation and reporting of results from multiple simultaneous analyses, which are becoming increasingly feasible...
Source: Environment International - April 14, 2015 Category: Environmental Health Authors: LaKind JS, Goodman M, Barr DB, Weisel CP, Schoeters G Tags: Environ Int Source Type: research

Sudden death in young persons with uncontrolled asthma - a nationwide cohort study in Denmark
Background: Asthma is a common chronic disease among young adults, and several studies have reported increased mortality rates in patients with asthma. However, no study has described sudden unexpected death in a nationwide setting in patients with uncontrolled asthma. We defined uncontrolled asthma as a previous hospital admittance because of asthma (of any severity) or when asthma was considered to have influenced the death according to the death certificate. The purpose of this study is to increase the medical focus on young persons with uncontrolled asthma and thereby hopefully aid in preventing sudden unexpected death...
Source: BMC Pulmonary Medicine - April 14, 2015 Category: Respiratory Medicine Authors: Anders GullachBjarke RisgaardThomas LyngeReza JabbariCharlotte GlingeStig HaunsøVibeke BackerBo WinkelJacob Tfelt-Hansen Source Type: research

Roseovarius antarcticus sp. nov., isolated from a decayed whale bone, in the Antarctic peninsula.
Abstract A pale yellow, ovoid- to rod-shaped and budding bacterium, designated strain M-S13-148T, was isolated from a decayed bone of whale from the eastern coast of King George Island, South Shetlands, Antarctica. Strain M-S13-148T exhibited motility, Gram-staining-negative, aerobic growth. Strain M-S13-148T gave positive reactions in experiments of catalase and oxidase. Growth was observed at pH 6.0-9.0, at 4-42℃ and with 0-14% NaCl. The novel strain contained diphosphatidylglycerol, phosphatidylglycerol, phosphatidylcholine, phosphatidylethanolamine and an unknown phospholipid as the major polar lipids. The do...
Source: International Journal of Systematic and Evolutionary Microbiology - April 14, 2015 Category: Microbiology Authors: Deng S, Jiang F, Chang X, Qu Z, Ren L, Zhang Y, Kan W, Da X, Qiu X, Kim M, Fang C, Peng F Tags: Int J Syst Evol Microbiol Source Type: research

Phaeobacterium nitratireducens gen. nov., sp. nov., a phototrophic gammaproteobacterium isolated from a sediment sample of Coringa mangrove forest, India.
Abstract The novel, brown coloured, Gram-negative-staining, rod shaped, motile phototrophic bacterium designated strain AK40T, was isolated in pure culture from a sediment sample collected from Coringa mangrove forest. Strain AK40T, containing bacteriochlorophyll a and carotenoid of rhodopin as major photosynthetic pigments. Strain AK40T was able to grow photoheterotrophically and could utilize a number of organic substrates. It was unable to grow photoautotrophically and did not utilize sulfide and thiosulfate as electron donors. Thiamine and riboflavin were required for growth of strain AK40T. The dominant fatty ...
Source: International Journal of Systematic and Evolutionary Microbiology - April 14, 2015 Category: Microbiology Authors: Nupur N, Tanuku NR, Shinichi T, Pinnaka AK Tags: Int J Syst Evol Microbiol Source Type: research

Draconibacterium sediminis sp. nov., isolated from the river sediment.
Abstract A Gram-negative, facultatively anaerobic and rod-shaped bacterium, designated strain JN14CK-3T, was isolated from the surface sediment of the Jiulong River of China and was characterized phenotypically and phylogenetically. Phylogenetic analysis of the 16S rRNA gene sequences indicated that strain JN14CK-3T belonged to the genus Draconibacterium, with the highest sequence similarity (98.3%) to Draconibacterium orientale FH5T. Whereas strain JN14CK-3T shared low similarities (<91.0%) with other type strains. The sole respiratory quinone was MK-7. The polar lipids were phosphatidylethanolamine, several un...
Source: International Journal of Systematic and Evolutionary Microbiology - April 14, 2015 Category: Microbiology Authors: Du J, Lai Q, Liu Y, Dong C, Xie Y, Shao Z Tags: Int J Syst Evol Microbiol Source Type: research

Clinical factors predicting risk for aspiration and respiratory aspiration among patients with Stroke.
CONCLUSION: dysphagia, Impaired or absent gag reflex were the best predictors both for Risk for aspiration and respiratory aspiration. PMID: 25885362 [PubMed - as supplied by publisher] (Source: Revista Latino-Americana de Enfermagem)
Source: Revista Latino-Americana de Enfermagem - April 14, 2015 Category: Nursing Authors: Oliveira AR, Costa AG, Morais HC, Cavalcante TF, Lopes MV, Araujo TL Tags: Rev Lat Am Enfermagem Source Type: research

Redefining the roles of mitochondrial DNA-encoded subunits in respiratory Complex I assembly.
Abstract Respiratory Complex I deficiency is implicated in numerous degenerative and metabolic diseases. In particular, mutations in several mitochondrial DNA (mtDNA)-encoded Complex I subunits including ND4, ND5 and ND6 have been identified in several neurological diseases. We previously demonstrated that these subunits played essential roles in Complex I assembly which in turn affected mitochondrial function. Here, we carried out a comprehensive study of the Complex I assembly pathway. We identified a new Complex I intermediate containing both membrane and matrix arms at an early assembly stage. We find that lack...
Source: Biochimica et Biophysica Acta - April 14, 2015 Category: Biochemistry Authors: Vartak R, Deng J, Fang H, Bai Y Tags: Biochim Biophys Acta Source Type: research

Profile of bile acids in fetal gallbladder and meconium using liquid chromatography-tandem mass spectrometry.
CONCLUSIONS: Sulfate-conjugated bile acid is found in urine, but rarely in stool. In this study, the gallbladder bile acid contained no sulfate conjugates, but these were present in intestinal contents and meconium. These results indicate that sulfate-conjugated bile acids are not excreted into the intestine through the biliary tract but originate from swallowed amniotic fluid that contains fetal urine. PMID: 25887994 [PubMed - as supplied by publisher] (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - April 14, 2015 Category: Chemistry Authors: Naritaka N, Suzuki M, Sato H, Takei H, Murai T, Kurosawa T, Iida T, Nittono H, Shimizu T Tags: Clin Chim Acta Source Type: research

History of passive antibody administration for prevention and treatment of infectious diseases
We describe the history of passive immunization to provide context for the series of articles to follow. The history of passive immunization with antibodies to prevent or treat infectious diseases is a story of different eras. There was an extraordinary era of discovery and clinical implementation before the chemical nature of antibodies was even known. This empirical process provided the resources and reagents used to describe and characterize humoral immunity, better define the chemical properties and structure of antibodies, and extend the clinical use of immunoglobulin products to treat or prevent multiple viral and ba...
Source: Current Opinion in HIV and AIDS - April 13, 2015 Category: Infectious Diseases Tags: ANTIBODIES FOR PREVENTION AND THERAPY: Edited by John R. Mascola and Richard A. Koup Source Type: research

Exercise capacity of cirrhotic patients with hepatopulmonary syndrome.
CONCLUSION: The group of cirrhotic patients diagnosed with HPS exhibited lower values for VO2 peak, distance walked in the 6MWT and respiratory muscle strength than the cirrhotic patients not diagnosed with HPS. PMID: 25864217 [PubMed - as supplied by publisher] (Source: Annals of Hepatology)
Source: Annals of Hepatology - April 13, 2015 Category: Gastroenterology Tags: Ann Hepatol Source Type: research

Control of a Reassortant Pandemic 2009 H1N1 Influenza Virus Outbreak in an Intensive Swine Breeding Farm: Effect of Vaccination and Enhanced Farm Management Practices
Conclusions Although our study design was sub-optimal for evaluating the effectiveness of the intervention, we provided suggestive evidence that H1N1pdm-targeted vaccination in sows/gilts, enhanced biosecurity, lengthening of weaning cycles, and constrains in cross-fostering of piglets may prove useful in controlling a reassortant H1N1pdm outbreak in an intensive swine breeding farm without possibility of applying an all-in/all-out system. Maternally-derived immunity was elicited and further virus circulation in piglets dropped to undetectable levels, while keeping farm productivity at full. The present field study also su...
Source: PLOS Currents Outbreaks - April 13, 2015 Category: Epidemiology Authors: Lapo Mughini-Gras Source Type: research

Pharyngeal aspiration of metal oxide nanoparticles showed potential of allergy aggravation effect to inhaled ovalbumin
Inhalation Toxicology, Ahead of Print. (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - April 13, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Size effects of single-walled carbon nanotubes on in vivo and in vitro pulmonary toxicity
Inhalation Toxicology, Ahead of Print. (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - April 13, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Pulmonary alveolar proteinosis: time to shift?
Expert Review of Respiratory Medicine, Ahead of Print. (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - April 13, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Vitamin D and omega-3 polyunsaturated fatty acid supplementation in athletes with exercise-induced bronchoconstriction: a pilot study
Expert Review of Respiratory Medicine, Ahead of Print. (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - April 13, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Effect of lung transplantation on heart rate response to exercise
Conclusions Corresponding to an increase in peak exercise capacity, percentage of heart rate reserve used improves significantly after lung transplantation, even at matching workloads, indicating a likely improvement in autonomic modulation. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - April 13, 2015 Category: Respiratory Medicine Source Type: research

Impacts of cardiac rehabilitation on ventricular repolarization indexes and ventricular arrhythmias in patients affected by coronary artery disease and type 2 diabetes
Conclusion Cardiac rehabilitation provided an improvement in the majority of ventricular repolarization indexes in patients with diabetes type 2 and CAD, decreasing the frequency of ventricular arrhythmias, particularly in those not treated by insulin. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - April 13, 2015 Category: Respiratory Medicine Source Type: research

Awareness of modifiable acute myocardial infarction risk factors has little impact on risk perception for heart attack among vulnerable patients
Conclusions The risk for developing AMI is underestimated among cardiac patients and it is only weakly linked with their awareness of AMI risk factors. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - April 13, 2015 Category: Respiratory Medicine Source Type: research

Attitudes towards euthanasia among Greek intensive care unit physicians and nurses
Conclusions Confusion prevails among Greek ICU physicians and nurses regarding the definition of euthanasia. The majority of staff disagrees with active euthanasia, but upholds its legalization. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - April 13, 2015 Category: Respiratory Medicine Source Type: research

Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials
Publication date: Available online 12 April 2015 Source:The Lancet Respiratory Medicine Author(s): Steven Pascoe , Nicholas Locantore , Mark T Dransfield , Neil C Barnes , Ian D Pavord Background The short-term benefits of inhaled corticosteroids for patients with chronic obstructive pulmonary disease (COPD) are greater in patients with evidence of eosinophilic airway inflammation. We investigated whether blood eosinophil count is a useful biomarker of the long-term effect of the inhaled corticosteroid fluticasone furoate on exacerbation frequency. Methods We did a post-hoc analysis of data from two replicate, randomise...
Source: The Lancet Respiratory Medicine - April 13, 2015 Category: Respiratory Medicine Source Type: research

IJERPH, Vol. 12, Pages 3993-4017: Exposure to Indoor Pollutants and Wheeze and Asthma Development during Early Childhood
Conclusion: Additional research to establish causality and evaluate interventions to prevent disease onset is needed. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - April 13, 2015 Category: Environmental Health Authors: Evridiki PatelarouNikolaos TzanakisFrank Kelly Tags: Review Source Type: research

Diaphragm ultrasound as indicator of respiratory effort in critically ill patients undergoing assisted mechanical ventilation: a pilot clinical study
IntroductionPressure-support ventilation, is widely used in critically ill patients; however, the relative contribution of patient’s effort during assisted breathing is difficult to measure in clinical conditions. Aim of the present study was to evaluate the performance of ultrasonographic indices of diaphragm contractile activity (respiratory excursion and thickening) in comparison to traditional indices of inspiratory muscle effort during assisted mechanical ventilation.MethodConsecutive patients admitted to the ICU after major elective surgery who met criteria for a spontaneous breathing trial with pressure support ve...
Source: BioMed Central - April 13, 2015 Category: Journals (General) Authors: Michele UmbrelloPaolo FormentiDaniela LonghiAndrea GalimbertiIlaria PivaAngelo PezziGiovanni MistralettiJohn J MariniGaetano Iapichino Source Type: research