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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 11.

The evaluation of an interactive web-based Pulmonary Rehabilitation programme: protocol for the WEB SPACE for COPD feasibility study
Introduction Pulmonary Rehabilitation (PR) is an evidence-based intervention that has been recommended in guidelines to be available to those who may benefit. However, not all patients with chronic obstructive pulmonary disease (COPD) have access to this service. Healthcare services have shown the need for the provision of PR in other forms to enable patient choice and service capacity. There is an increase in evidence for the use of the internet in the management of long-term conditions to provide education and promote self-management. The aim of this study is to see if an interactive web-based PR programme is a feasible ...
Source: BMJ Open - August 25, 2015 Category: Journals (General) Authors: Chaplin, E., Hewitt, S., Apps, L., Edwards, K., Brough, C., Glab, A., Bankart, J., Jacobs, R., Boyce, S., Williams, J., Singh, S. Tags: Open access, Rehabilitation medicine, Respiratory medicine Protocol Source Type: research

Children Learning About Secondhand Smoke (CLASS II): protocol of a pilot cluster randomised controlled trial
Introduction Exposure to secondhand smoke (SHS) increases children’s risk of acquiring chest and ear infections, tuberculosis, meningitis and asthma. Smoking bans in public places (where implemented) have significantly reduced adults’ exposure to SHS. However, for children, homes remain the most likely place for them to be exposed to SHS. Additional measures are therefore required to protect children from SHS. In a feasibility study in Dhaka, Bangladesh, we have shown that a school-based smoke-free intervention (SFI) was successful in encouraging children to negotiate and implement smoking restrictions in homes...
Source: BMJ Open - August 25, 2015 Category: Journals (General) Authors: Siddiqi, K., Huque, R., Jackson, C., Parrott, S., Dogar, O., Shah, S., Thomson, H., Sheikh, A. Tags: Open access, Public health, Smoking and tobacco Protocol Source Type: research

Inhaled alpha-proteinase inhibitor therapy in patients with cystic fibrosis
Inhaled alpha1-proteinase inhibitor (PI) is known to reduce neutrophil elastase burden in some patients with CF. This phase 2a study was designed to test inhaled Alpha-1 HC, a new aerosolized alpha1-PI formulation, in CF patients. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - August 25, 2015 Category: Respiratory Medicine Authors: Amit Gaggar, Junliang Chen, James F. Chmiel, Henry L. Dorkin, Patrick A. Flume, Rhonda Griffin, David Nichols, Scott H. Donaldson Tags: Original Article Source Type: research

Oceanobacillus bengalensis sp. nov., a bacterium isolated from seawater of the Bay of Bengal.
Abstract A Gram-stain positive, motile, and subterminal endospore-forming rod-shaped bacterium, designated strain Ma-21(T), was isolated from seawater of the Bay of Bengal. Strain Ma-21(T) was found to grow optimally at 37 °C and pH 8.0 with 3 % (w/v) NaCl. Phylogenetic analyses showed that strain Ma-21(T) forms a distinct phylogenetic lineage close to Oceanobacillus chungangensis CAU 1051(T), Oceanobacillus caeni S-11(T), Oceanobacillus arenosus CAU 1183(T), Oceanobacillus halophilum GD01(T) and Ornithinibacillus heyuanensis GIESS003(T) in the family Bacillaceae. The cell wall of strain Ma-21(T) was found to co...
Source: Antonie van Leeuwenhoek - August 25, 2015 Category: Microbiology Authors: Yongchang O, Xiang W, Wang G Tags: Antonie Van Leeuwenhoek Source Type: research

Potential mechanisms regulating pulmonary pathology in inflammatory bowel disease.
Abstract Inflammatory bowel disease is associated with a number of comorbidities that arise at extraintestinal sites, including the lung. Pulmonary manifestations reported in inflammatory bowel disease include bronchiectasis, chronic bronchitis and importantly, a range of subclinical respiratory abnormalities that are often overlooked in routine clinical evaluation. Whereas evidence for the pulmonary manifestations of Inflammatory bowel disease is increasing, little is known about the immunologic and physiologic mechanisms regulating cross-talk between the gut and lung during disease. This review examines reported ...
Source: Journal of Leukocyte Biology - August 25, 2015 Category: Hematology Authors: Mateer SW, Maltby S, Marks E, Foster PS, Horvat JC, Hansbro PM, Keely S Tags: J Leukoc Biol Source Type: research

Circulatory support devices: fundamental aspects and clinical management of bleeding and thrombosis.
This article is protected by copyright. All rights reserved. PMID: 26302994 [PubMed - as supplied by publisher] (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - August 25, 2015 Category: Hematology Authors: Susen S, Rauch A, Van Belle E, Vincentelli A, Lenting PJ Tags: J Thromb Haemost Source Type: research

Future Research Directions in Asthma: An NHLBI Working Group Report.
This report summarizes the workshop, producing recommendations to guide future research in asthma. PMID: 26305520 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - August 25, 2015 Category: Respiratory Medicine Authors: Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau Tags: Am J Respir Crit Care Med Source Type: research

Effects of Arm Bracing on Expiratory Flow Limitation and Lung Volume in Elderly COPD Subjects.
CONCLUSIONS: The decreased EFL in the arm bracing position may be caused by breathing at a higher lung volume than in the erect position, which may be one of the factors relieving dyspnea in elderly COPD patients. PMID: 26306736 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - August 25, 2015 Category: Respiratory Medicine Authors: Ogino T, Mase K, Nozoe M, Wada T, Uchiyama Y, Fukuda Y, Domen K Tags: Respir Care Source Type: research

Respiratory Therapist Job Perceptions: The Impact of Protocol Use.
CONCLUSIONS: The study extends prior research by examining how the use of respiratory care protocols favorably affects RTs' perceptions of job satisfaction, turnover intention, and job stress. In a time of increasing demand for respiratory care services, protocols may enhance retention of RTs. PMID: 26306735 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - August 25, 2015 Category: Respiratory Medicine Authors: Metcalf AY, Stoller JK, Habermann M, Fry TD Tags: Respir Care Source Type: research

Umboniibacter roseus sp. nov., isolated from coastal sea water.
Abstract A Gram-reaction-negative, non-motile, strictly aerobic darkness orange pigmented and rod-shaped bacterial isolate, designated strain 14-121-B13T, was isolated from surface seawater off the coast of the South Sea at Namhae-gun, Republic of Korea. Cells were catalase- and oxidase-positive and required NaCl for growth. Strain 14-121-B13T grew optimally at 30 °C, in the presence of 2% (w/v) NaCl and at pH7.5-8.0. Neighbour-joining, maximum-likelihood and maximum-parsimony phylogenetic trees based on 16S rRNA gene sequences showed that strain 14-121-B13T clustered with the type strain of Umboniibacter marinipu...
Source: International Journal of Systematic and Evolutionary Microbiology - August 25, 2015 Category: Microbiology Authors: Sung HR, Kim M, Shin KS Tags: Int J Syst Evol Microbiol Source Type: research

Pseudoclavibacter terrae sp. nov. isolated from rhizosphere soil of Ophiopogon japonicus.
Abstract Strain THG-MD12T, a Gram-positive, aerobic, non-motile, rod-shaped bacterium was isolated from rhizosphere soil of Ophiopogon japonicus in PR China. Strain THG-MD12T was closely related to members of the genus Pseudoclavibacter, showed the highest 16S rRNA gene sequence similarities with Pseudoclavibacter helvolus KCTC 19531T (98.8 %) and Pseudoclavibacter chunganggensis KCTC 14526T (96.9 %). DNA-DNA hybridization showed 41.9±2.1 % and 12.4±0.9 % DNA re-ssociation with P. helvolus KCTC 19531T and P. chunganggensis KCTC 14526T, respectively. Chemotaxonomic data revealed that strain THG-MD12T possesses men...
Source: International Journal of Systematic and Evolutionary Microbiology - August 25, 2015 Category: Microbiology Authors: Du J, Singh H, Yang JE, Yin CS, Kook M, Yu H, Yi TH Tags: Int J Syst Evol Microbiol Source Type: research

Brachybacterium hainanense sp. nov., isolated from Noni (Morinda citrifolia L.) branch.
Abstract A Gram-stain-positive bacterial strain, designated as NR2T, isolated from Noni (Morinda citrifolia L.) branch was investigated using a polyphasic taxonomic approach. The cells were small coccoid to ovoid, non-spore-forming and motile. Phylogenetic analysis based on 16S rRNA gene sequences showed that the strain was recognized as a species of the genus Brachybacterium, to which seven closest neighbours being Brachybacterium squillarum M-6-3T (97.90% similarity), Brachybacterium faecium DSM 4810T (97.50%), Brachybacterium sacelli LMG 20345T (97.41%), Brachybacterium phenoliresistens phenol-AT (97.36%), Brach...
Source: International Journal of Systematic and Evolutionary Microbiology - August 25, 2015 Category: Microbiology Authors: Liu Y, Zhai L, Yao S, Cao Y, Cao Y, Zhang X, Su J, Ge Y, Zhao R, Cheng C Tags: Int J Syst Evol Microbiol Source Type: research

Donghicola tyrosinivorans sp. nov., a tyrosine-degrading bacterium isolated from seawater.
Abstract A Gram-stain-negative, non-motile, aerobic bacterium, strain 13-93-B1T, was isolated from seawater off Jeju Island, Republic of Korea and was subjected to polyphasic taxonomic study. Cells formed ivory colonies and were ovoid to rod-shaped. This strain catalase-positive, oxidase-negative and grew optimally at 30 ºC, in the presence of 1-2% (w/v) NaCl and at pH 7.0-7.5. It did not synthesize bacteriochlorophyll a. Neighbour-joining, maximum-likelihood and maximum-parsimony phylogenetic trees based on 16S rRNA gene sequences revealed that strain 13-93-B1T clustered with the type strain Donghicola eburneus K...
Source: International Journal of Systematic and Evolutionary Microbiology - August 25, 2015 Category: Microbiology Authors: Sung HR, Lee JM, Kim M, Yun BR, Shin KS Tags: Int J Syst Evol Microbiol Source Type: research

Assessment of Indian medicinal plants for the treatment of asthma
The present study documented the traditional knowledge of medicinal plants which are used for the treatment of respiratory diseases asthma in India by various tribal communities. The present study is based on the literature survey from various sources and it provides a comprehensive knowledge about the use of plants and their parts for the treatment of asthma by various tribal communities in... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - August 24, 2015 Category: Complementary Medicine Source Type: research

Tissue- and age-dependent expression of the bovine DEFB103 gene and protein
In conclusion, bovine DEFB103 gene expression is most abundant in stratified squamous epithelium with DEFB103 protein localised to basal epithelial cells. These observations are consistent with proposed roles for DEFB103 in DC recruitment and repair of stratified squamous epithelium. (Source: Cell and Tissue Research)
Source: Cell and Tissue Research - August 24, 2015 Category: Cytology Source Type: research

Transitional Changes in Cerebral Blood Volume at Birth
Conclusions: In healthy newborns, CBV decreased over the whole study period. This likely reflects a physiological process. The impact and clinical relevance of different CBV behaviour during immediate transition needs to be investigated in further studies.Neonatology 2015;108:253-258 (Source: Neonatology)
Source: Neonatology - August 24, 2015 Category: Perinatology & Neonatology Source Type: research

Expression and DNA methylation status of the Rap2B gene in human bronchial epithelial cells treated by cigarette smoke condensate
Inhalation Toxicology, Ahead of Print. (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - August 24, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Analysis of cigarette smoking mechanism by real time video-endoscopic documentation
Inhalation Toxicology, Ahead of Print. (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - August 24, 2015 Category: Respiratory Medicine Tags: article Source Type: research

The transient but not resident (TBNR) microbiome: a Yin Yang model for lung immune system
Inhalation Toxicology, Ahead of Print. (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - August 24, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Are asthma patients at increased risk of clinical depression? A longitudinal cohort study
Journal of Asthma, Ahead of Print. (Source: Journal of Asthma)
Source: Journal of Asthma - August 24, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Predictors of flourishing for adolescents with asthma
Journal of Asthma, Ahead of Print. (Source: Journal of Asthma)
Source: Journal of Asthma - August 24, 2015 Category: Respiratory Medicine Tags: article Source Type: research

The influence of asthma control on psychosocial outcomes for pregnant women with asthma
Journal of Asthma, Ahead of Print. (Source: Journal of Asthma)
Source: Journal of Asthma - August 24, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Diagnosis of asthma: the challenge goes on
Journal of Asthma, Ahead of Print. (Source: Journal of Asthma)
Source: Journal of Asthma - August 24, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Efficacy of an in-home test kit in reducing dust mite allergen levels: results of a randomized controlled pilot study
Journal of Asthma, Ahead of Print. (Source: Journal of Asthma)
Source: Journal of Asthma - August 24, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Dual bronchodilator therapy with aclidinium bromide/formoterol fumarate for chronic obstructive pulmonary disease
Expert Review of Respiratory Medicine, Ahead of Print. (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - August 24, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Early promise for infant RSV vaccine development
Publication date: Available online 23 August 2015 Source:The Lancet Respiratory Medicine Author(s): Emma Wilkinson (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - August 24, 2015 Category: Respiratory Medicine Source Type: research

Lung function trajectories differ in patients with COPD
Publication date: Available online 23 August 2015 Source:The Lancet Respiratory Medicine Author(s): Talha Khan Burki (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - August 24, 2015 Category: Respiratory Medicine Source Type: research

Experts split on 21st Century Cures Act
Publication date: Available online 23 August 2015 Source:The Lancet Respiratory Medicine Author(s): Talha Khan Burki (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - August 24, 2015 Category: Respiratory Medicine Source Type: research

Clinical study replicability and the pursuit of excellence
Comparisons of processes of care are common in critical care research. Often, these processes are neither explicit nor replicable and this can result in seemingly irreconcilable results. Here, we briefly review the article by Taniguchi and colleagues, who studied liberation from mechanical ventilation by using either a computerized weaning protocol or one driven by respiratory therapists. We discuss the implications of explicit protocols increasing replicability in clinical research. (Source: Critical Care)
Source: Critical Care - August 24, 2015 Category: Intensive Care Authors: Michael LanspaEliotte HirshbergRussell MillerAlan Morris Source Type: research

Dynamics of respiratory and cardiac CSF motion revealed with real-time simultaneous multi-slice EPI velocity phase contrast imaging
Publication date: 15 November 2015 Source:NeuroImage, Volume 122 Author(s): Liyong Chen, Alexander Beckett, Ajay Verma, David A. Feinberg Cerebrospinal fluid (CSF) dynamics have been mostly studied with cardiac-gated phase contrast MRI combining signal from many cardiac cycles to create cine-phase sampling of one time-averaged cardiac cycle. The relative effects of cardiac and respiratory changes on CSF movement are not well understood. There is possible respiration-driven movement of CSF in ventricles, cisterns, and subarachnoid spaces which has not been characterized with velocity measurements. To date, commonly us...
Source: NeuroImage - August 24, 2015 Category: Neuroscience Source Type: research

Risk Factors for Mortality and Endotracheal Intubation after Methadone Intoxication
This article is protected by copyright. All rights reserved. (Source: Basic and Clinical Pharmacology and Toxicology)
Source: Basic and Clinical Pharmacology and Toxicology - August 24, 2015 Category: Drugs & Pharmacology Authors: Hossein Hassanian‐Moghaddam, Kambiz Soltaninejad, Shahin Shadnia, Ali Kabir, Mitra Movahed, Amirhossein Mirafzal Tags: Original Article Source Type: research

Republished: Respiratory microbiota: addressing clinical questions, informing clinical practice
Over the last decade, technological advances have revolutionised efforts to understand the role played by microbes in airways disease. With the application of ever more sophisticated techniques, the literature has become increasingly inaccessible to the non-specialist reader, potentially hampering the translation of these gains into improvements in patient care. In this article, we set out the key principles underpinning microbiota research in respiratory contexts and provide practical guidance on how best such studies can be designed, executed and interpreted. We examine how an understanding of the respiratory microbiota ...
Source: Postgraduate Medical Journal - August 24, 2015 Category: Journals (General) Authors: Rogers, G. B., Shaw, D., Marsh, R. L., Carroll, M. P., Serisier, D. J., Bruce, K. D. Tags: Open access Reviews Source Type: research

Influenza follicles in the posterior pharyngeal wall
Introduction Influenza develops rapidly with a high fever accompanying chills and malaise. Respiratory symptoms such as nasal discharge, cough and sore throat, gastrointestinal symptoms such as vomiting and diarrhoea, headache, joint pain, muscle pain, etc., frequently accompany it, but they are non-specific symptoms. On the other hand, influenza follicles in the posterior pharyngeal wall are very characteristic physical findings for the seasonal influenza diagnosis.1 Sakuma’s well-known paediatric pharynx findings textbook in Japan2 notes influenza follicles in the posterior pharyngeal wall. However, the textbook is...
Source: Postgraduate Medical Journal - August 24, 2015 Category: Journals (General) Authors: Kenzaka, T. Tags: Journalology, Immunology (including allergy), Drugs: infectious diseases, Headache (including migraine), Pain (neurology), Hypertension, Clinical diagnostic tests, Ear, nose and throat/otolaryngology, Ethics Images in medicine Source Type: research

Oligogenic inheritance of optineurin (OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP‐43‐negative inclusions of C9ORF72‐ALS
This study: (i) investigated the frequency of mt OPTN in ALS patients in England; (ii) characterized the clinical and neuropathological features of ALS associated with a mt OPTN; and (iii) investigated optineurin neuropathology in C9ORF72‐related ALS (C9ORF72‐ALS). We identified a heterozygous p.E322K missense mutation in exon 10 of OPTN in one familial ALS patient who additionally had a C9ORF72 mutation. This patient had bulbar, limb and respiratory disease without cognitive problems. Neuropathology revealed motor neurone loss, trans‐activation response DNA protein 43 (TDP‐43)‐positive neuronal and glial cytopla...
Source: Neuropathology - August 24, 2015 Category: Neurology Authors: Joanna J. Bury, J. Robin Highley, Johnathan Cooper‐Knock, Emily F. Goodall, Adrian Higginbottom, Christopher J. McDermott, Paul G. Ince, Pamela J. Shaw, Janine Kirby Tags: Original Article Source Type: research

In vivo free‐breathing DTI and IVIM of the whole human heart using a real‐time slice‐followed SE‐EPI navigator‐based sequence: A reproducibility study in healthy volunteers
Conclusion: The slice‐following DWI SE‐EPI sequence is a promising solution for clinical implementation, offering a robust improved workflow for further evaluation of DWI in cardiology. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc. (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - August 24, 2015 Category: Radiology Authors: Kevin Moulin, Pierre Croisille, Thorsten Feiweier, Benedicte M.A. Delattre, Hongjiang Wei, Benjamin Robert, Olivier Beuf, Magalie Viallon Tags: Full Paper Source Type: research

Mayo clinic experience of lung transplantation in pulmonary lymphangioleiomyomatosis
Lymphangioleiomyomatosis (LAM) is a rare, cystic lung disease that generally results in progressive decline in lung function. Despite advancement of pharmacological therapy for LAM, lung transplantation remains an important option for women with end-stage LAM. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 24, 2015 Category: Respiratory Medicine Authors: Kamonpun Ussavarungsi, Xiaowen Hu, J.P. Scott, David B. Erasmus, Jorge M. Mallea, Francisco Alvarez, Augustine S. Lee, Cesar A. Keller, Jay H. Ryu, Charles D. Burger Source Type: research

Letter to the Editor: “Risk factors for postoperative pneumonia after lung cancer surgery and impact of pneumonia on survival”
We have read with great interest the paper by Simonsen et al [1] on risk factors for postoperative pneumonia (POP) and the impact pneumonia has on survival of people after surgery for lung cancer. The authors stated in the conclusion paragraph that the presence of some risk factors for development of POP “may lead to specific prophylactic measures including individualised antibiotic therapy” [1]. Of note, preoperative exercise training was not mentioned as a prophylactic measure. It is well-known that preoperative exercise capacity (i.e. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 24, 2015 Category: Respiratory Medicine Authors: Vinicius Cavalheri, Kylie Hill Tags: Correspondence Source Type: research

Quantifying the shape of the maximal expiratory flow–volume curve in mild COPD
Publication date: December 2015 Source:Respiratory Physiology & Neurobiology, Volume 219 Author(s): Paolo B. Dominelli, Glen E. Foster, Jordan A. Guenette, Hans C. Haverkamp, Neil D. Eves, Giulio S. Dominelli, William R. Henderson, Denis E. O’Donnell, A. William Sheel Maximal expiratory flow–volume (MEFV) curve evaluation using absolute and percent predicted values of flow and volume are used to diagnose respiratory disease, but the shape of the curve is rarely used. Three mathematical methods were used to quantify shape of MEFV curves in subjects with mild COPD (n =19) and matched healthy controls (...
Source: Respiratory Physiology and Neurobiology - August 24, 2015 Category: Respiratory Medicine Source Type: research

Opposing actions of TRPV4 channel activation in the lung vasculature
Conclusions Activated TRPV4 channels increase pulmonary vascular resistance and vasodilate the main pulmonary artery. Graphical abstract (Source: Respiratory Physiology and Neurobiology)
Source: Respiratory Physiology and Neurobiology - August 24, 2015 Category: Respiratory Medicine Source Type: research