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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

Neonatal metabolic acidosis at birth: In search of a reliable marker
Conclusion Birth-related neonatal eucapnic pH is described as the most pertinent marker of NMA at birth. The various means of calculating this value and the level below which it seems to play a possible pathogenic role are presented. (Source: Gynecologie Obstetrique and Fertilite)
Source: Gynecologie Obstetrique and Fertilite - May 21, 2016 Category: OBGYN Source Type: research

Pulmonary function tests correlated with thoracic volumes in adolescent idiopathic scoliosis
This article is protected by copyright. All rights reserved (Source: Journal of Orthopaedic Research)
Source: Journal of Orthopaedic Research - May 21, 2016 Category: Orthopaedics Authors: Charles G.T. Ledonio, Benjamin E. Rosenstein, David W. Polly, Charles E. Johnston, Warren E. Regelmann, David J. Nuckley Tags: Special Issue Research Article Source Type: research

Effect of exercise training on sleep apnea: A systematic review and meta-analysis
Obstructive sleep apnea (OSA) is difficult to manage for those who are intolerant or noncompliant with standard facial mask treatment options. Current treatment options do not address the underlying cause of OSA. Exercise as a treatment option has been found to improve OSA indices. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - May 21, 2016 Category: Respiratory Medicine Authors: Kenneth D. Aiello, William G. Caughey, Bhargava Nelluri, Ashwini Sharma, Farouk Mookadam, Martina Mookadam Source Type: research

Pulmonary tuberculosis: Resistance pattern to first line anti-tuberculosis drugs in the Coimbra District, 2000–2011
Publication date: Available online 20 May 2016 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): R. Eufrásio, M. Alcobia, L. Correia (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - May 21, 2016 Category: Respiratory Medicine Source Type: research

Asthma prevalence in Portuguese preschool children: The latest scientific evidence
Publication date: Available online 20 May 2016 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): P.T.B.S. Branco, R.A.O. Nunes, M.C.M. Alvim-Ferraz, F.G. Martins, C. Ferraz, L.G. Vaz, S.I.V. Sousa (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - May 21, 2016 Category: Respiratory Medicine Source Type: research

Altered gene expression in the lower respiratory tract of Car6 (-/-) mice.
In this study, the transcriptional effects of CA VI deficiency were investigated in both trachea and lung of Car6 (-/-) mice using a cDNA microarray analysis. Functional clustering of the results indicated significant changes of gene transcription in the lower airways. The altered biological processes included antigen transport by M-cells, potassium transport, muscle contraction, and thyroid hormone synthesis. Immunohistochemical staining confirmed the absence of CA VI in the submandibular gland of Car6 (-/-) mice. Immunostaining of the trachea and lung samples revealed no differences between the knockout and wild type gro...
Source: Transgenic Research - May 21, 2016 Category: Genetics & Stem Cells Authors: Patrikainen MS, Pan P, Barker HR, Parkkila S Tags: Transgenic Res Source Type: research

Re-evaluation of the WHO (2010) formaldehyde indoor air quality guideline for cancer risk assessment.
Abstract In 2010, the World Health Organization (WHO) established an indoor air quality guideline for short- and long-term exposures to formaldehyde (FA) of 0.1 mg/m(3) (0.08 ppm) for all 30-min periods at lifelong exposure. This guideline was supported by studies from 2010 to 2013. Since 2013, new key studies have been published and key cancer cohorts have been updated, which we have evaluated and compared with the WHO guideline. FA is genotoxic, causing DNA adduct formation, and has a clastogenic effect; exposure-response relationships were nonlinear. Relevant genetic polymorphisms were not identified. Normal i...
Source: Archives of Toxicology - May 21, 2016 Category: Toxicology Authors: Nielsen GD, Larsen ST, Wolkoff P Tags: Arch Toxicol Source Type: research

Gas Exchange Models for a Flexible Insect Tracheal System.
Abstract In this paper two models for movement of respiratory gases in the insect trachea are presented. One model considers the tracheal system as a single flexible compartment while the other model considers the trachea as a single flexible compartment with gas exchange. This work represents an extension of Ben-Tal's work on compartmental gas exchange in human lungs and is applied to the insect tracheal system. The purpose of the work is to study nonlinear phenomena seen in the insect respiratory system. It is assumed that the flow inside the trachea is laminar, and that the air inside the chamber behaves as an i...
Source: Acta Biotheoretica - May 21, 2016 Category: Biomedical Science Authors: Simelane SM, Abelman S, Duncan FD Tags: Acta Biotheor Source Type: research

Geographic accessibility of pulmonologists for adults with chronic obstructive pulmonary disease: United States, 2013.
CONCLUSIONS: County-level geographic variations in pulmonologist access for adults with COPD suggest that those adults with limited access will have to depend upon care from primary care physicians. PMID: 27221645 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - May 21, 2016 Category: Respiratory Medicine Authors: Croft JB, Lu H, Zhang X, Holt JB Tags: Chest Source Type: research

Pulmonary Disease Caused by Non-Tuberculous Mycobacteria
We describe the epidemiology of NTM pulmonary disease as well as emerging NTM pathogens and their geographical distribution in non-cystic fibrosis patients in Europe. We also review recent innovations for the diagnosis of NTM pulmonary disease, summarize treatment recommendations, and identify future research priorities to improve the management of patients affected by NTM pulmonary disease.Respiration (Source: Respiration)
Source: Respiration - May 20, 2016 Category: Respiratory Medicine Source Type: research

Applying Adult Ventilator-associated Pneumonia Bundle Evidence to the Ventilated Neonate.
This article describes a VAP prevention protocol developed to address care practices surrounding hand hygiene, intubation, feeding, suctioning, positioning, oral care, and respiratory equipment in the NICU. IMPLICATIONS FOR RESEARCH: Implementation of this VAP prevention protocol in other facilities with appropriate monitoring and tracking would provide broader support for standardization of care. Individual components of this VAP protocol could be studied to strengthen the inclusion of each; however, bundled interventions are often considered stronger when implemented as a whole. PMID: 27195470 [PubMed - as suppli...
Source: Advances in Neonatal Care - May 20, 2016 Category: Nursing Authors: Weber CD Tags: Adv Neonatal Care Source Type: research

[Comment] Respiratory medicine: a call for papers
The Lancet and The Lancet Respiratory Medicine would like to hear from authors of research papers in any area of clinical research related to respiratory medicine and critical care as the two journals are once again planning special issues timed to coincide with the 2016 European Respiratory Society (ERS) International Congress, in London, UK, on Sept 3–7. We welcome high-quality submissions from this thriving research community, particularly clinical trials and research that will change clinical practice or current thinking. (Source: LANCET)
Source: LANCET - May 20, 2016 Category: Journals (General) Authors: Emma Grainger, Sabine Kleinert Tags: Comment Source Type: research

Pulmonary Crohn's Disease in Down Syndrome: A Link or Linkage Problem
We present the case of a 5-year-old girl with known DS and a history of chronic intermittent abdominal pain who presented with persistent pneumonia. Her workup included a chest computed tomography (CT) scan that showed multiple noncalcified pulmonary nodules. An extensive infectious workup was done that was negative. CT-guided needle biopsy of the lung nodules showed necrotizing granulomas. This raised concern for primary CD with extraintestinal pulmonary manifestation. An esophagogastroduodenoscopy and colonoscopy were performed, and colon biopsies showed scattered epithelioid granulomas. Based on this information, there ...
Source: Case Reports in Gastroenterology - May 20, 2016 Category: Gastroenterology Source Type: research

Middle East Respiratory Syndrome Coronavirus Transmission in Extended Family, Saudi Arabia, 2014.
Abstract Risk factors for human-to-human transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) are largely unknown. After MERS-CoV infections occurred in an extended family in Saudi Arabia in 2014, relatives were tested by using real-time reverse transcription PCR (rRT-PCR) and serologic methods. Among 79 relatives, 19 (24%) were MERS-CoV positive; 11 were hospitalized, and 2 died. Eleven (58%) tested positive by rRT-PCR; 8 (42%) tested negative by rRT-PCR but positive by serology. Compared with MERS-CoV-negative adult relatives, MERS-CoV-positive adult relatives were older and more likely to be m...
Source: Emerging Infectious Diseases - May 20, 2016 Category: Infectious Diseases Authors: Arwady MA, Alraddadi B, Basler C, Azhar EI, Abuelzein E, Sindy AI, Sadiq BM, Althaqafi AO, Shabouni O, Banjar A, Haynes LM, Gerber SI, Feikin DR, Madani TA Tags: Emerg Infect Dis Source Type: research

Pediatric perioperative adverse events requiring rapid response: a retrospective case–control study
ConclusionsDecreased age, increased comorbidities, multiple (vs single) surgical services, operating room (vs nonoperating room) location, and decreased staff experience were associated with increased risk of AN! events, which were predominantly respiratory in origin. (Source: Pediatric Anesthesia)
Source: Pediatric Anesthesia - May 20, 2016 Category: Anesthesiology Authors: Laura E. Schleelein, Ariel M. Vincent, Abbas F. Jawad, Eric Y. Pruitt, Genna D. Kreher, Mohamed A. Rehman, Theodora K. Goebel, David E. Cohen, Scott D. Cook‐Sather Tags: Research Report Source Type: research

The Influence of a Dynamic Elastic Garment on Musculoskeletal and Respiratory Wellness in Computer Users.
DISCUSSION: This prospective study demonstrated positive short-term impact of the Posture Shirt® on both subjective and objective measures of posture, lung function, grip strength, fatigue, and productivity. PMID: 27191925 [PubMed - as supplied by publisher] (Source: International Journal of Occupational Safety and Ergonomics)
Source: International Journal of Occupational Safety and Ergonomics - May 20, 2016 Category: Occupational Health Tags: Int J Occup Saf Ergon Source Type: research

Mortality predictors in recipients developing acute respiratory distress syndrome due to pneumonia after kidney transplantation.
CONCLUSION: Infection-related mortality in kidney transplant patients with ARDS was associated with high serum creatinine level and severe ARDS. PMID: 27185552 [PubMed - as supplied by publisher] (Source: Renal Failure)
Source: Renal Failure - May 20, 2016 Category: Urology & Nephrology Tags: Ren Fail Source Type: research

Advancing our understanding of infant bronchiolitis through phenotyping and endotyping: Clinical and molecular approaches.
Authors: Hasegawa K, Dumas O, Hartert TV, Camargo CA Abstract INTRODUCTION: Bronchiolitis is a major public health problem worldwide. However, no effective treatment strategies are available, other than supportive care. Areas Covered: Although bronchiolitis has been considered a single disease diagnosed based on clinical characteristics, emerging evidence supports both clinical and pathobiological heterogeneity. The characterization of this heterogeneity supports the concept that bronchiolitis consists of multiple phenotypes or consistent grouping of characteristics. Expert Commentary: Using unbiased statistical ap...
Source: Expert Review of Respiratory Medicine - May 20, 2016 Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research

The role of air pollution in COPD and implications for therapy.
Authors: Lopez-Campos JL, Marquez-Martin E, Soriano JB Abstract INTRODUCTION: Exposure to many environmental conditions, apart from tobacco, as a risk factor for developing chronic obstructive pulmonary disease (COPD) has been comprehensively studied. Areas covered: Global estimates of air pollution depict a scenario of a considerable burden on respiratory health. Exposure to biomass smoke and occupational inhaled agents have been described as potentially related to causing or aggravating COPD. A number of emerging natural or accidental disasters have been suggested as a new source of exposure. Management of COPD p...
Source: Expert Review of Respiratory Medicine - May 20, 2016 Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research

Exercise intolerance in pulmonary hypertension: mechanism, evaluation and clinical implications.
Authors: Babu AS, Arena R, Myers J, Padmakumar R, Maiya AG, Cahalin LP, Waxman AB, Lavie CJ Abstract INTRODUCTION: Exercise intolerance in pulmonary hypertension (PH) is a major factor affecting activities of daily living and quality of life. Evaluation strategies (i.e., non-invasive and invasive tests) are integral to providing a comprehensive assessment of clinical and functional status. Despite a growing body of literature on the clinical consequences of PH, there are limited studies discussing the contribution of various physiological systems to exercise intolerance in this patient population. Areas covered: Th...
Source: Expert Review of Respiratory Medicine - May 20, 2016 Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research

Correction to: Infection in cystic fibrosis: impact of the environment and climate.
Authors: PMID: 27187679 [PubMed - in process] (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - May 20, 2016 Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research

Occupational exposure and risk of Chronic Obstructive Pulmonary Disease: a systematic review and meta-analysis.
Authors: Alif SM, Dharmage SC, Bowatte G, Karahalios A, Benke G, Dennekamp M, Mehta AJ, Miedinger D, Künzli N, Probst-Hensch N, Matheson MC Abstract INTRODUCTION: Due to contradictory literature we have performed a systematic review and meta-analyse of population-based studies that have used Job Exposure Matrices to assess occupational exposure and risk of Chronic Obstructive Pulmonary Disease (COPD). Areas covered: Two researchers independently searched databases for published articles using predefined inclusion criteria. Study quality was assessed, and results pooled for COPD and chronic bronchitis for exposure ...
Source: Expert Review of Respiratory Medicine - May 20, 2016 Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research

Can we improve clinical outcomes in patients with pneumonia treated with antibiotics in the intensive care unit?
Authors: Nicolau DP, Dimopoulos G, Welte T, Luyt CE Abstract Introduction Pneumonia in the intensive care unit (ICU) is associated with high morbidity, mortality and healthcare costs. However, treatment outcomes with conventional intravenous (IV) antibiotics remain suboptimal, and there is an urgent need for improved therapy options. Areas covered We review how clinical outcomes in patients with pneumonia treated in the ICU could be improved; we discuss the importance of choosing appropriate outcome measures in clinical trials, highlight the current suboptimal outcomes in patients with pneumonia, and outline potent...
Source: Expert Review of Respiratory Medicine - May 20, 2016 Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research

Deleterious effects of incense smoke exposure on kidney function and architecture in male albino rats.
CONCLUSION: Long-term exposure to incense smoke may have deleterious effects on kidney function and architecture. Though, inhalation is the rout of exposure, findings of this study underscore that incense smoke may also have an effect on non-pulmonary tissues. PMID: 27180632 [PubMed - as supplied by publisher] (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - May 20, 2016 Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research

The effects of the 5-HT2A receptor antagonist sarpogrelate hydrochloride on chronic hypoxic pulmonary hypertension in rats.
CONCLUSION: Administration of SPG ameliorated the development of CH-PH by stimulating apoptosis in and inhibiting proliferation of PASMCs. PMID: 27191897 [PubMed - as supplied by publisher] (Source: Experimental Lung Research)
Source: Experimental Lung Research - May 20, 2016 Category: Respiratory Medicine Tags: Exp Lung Res Source Type: research

Preliminary feasibility and modelling of a liquid matrix Dictyostelium discoideum virulence assay for Pseudomonas aeruginosa.
DISCUSSION: A liquid matrix D. discoideum model for the analysis of P. aeruginosa virulence in a eukaryotic host is feasible, but further validation of the model is required before it may be employed in routine setting. PMID: 27181169 [PubMed - as supplied by publisher] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - May 20, 2016 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Correlation of B-type natriuretic peptide levels and echocardiographic parameters in preterm infants with patent ductus arteriosus.
CONCLUSION: BNP levels and echocardiographic parameters showed a positive correlation, but the significance of the correlations differed according to the postnatal age, especially during the first few days of life. PMID: 27186229 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 20, 2016 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Complete occlusion of the right middle cerebral artery associated with Mycoplasma pneumoniae pneumonia.
We report a case of a 5-year-old girl who developed left hemiparesis and left facial palsy, 6 days after the initiation of fever and respiratory symptoms due to pneumonia. Chest radiography, conducted upon admission, showed pneumonic infiltration and pleural effusion in the left lung field. Brain magnetic resonance imaging showed acute ischemic infarction in the right middle cerebral artery territory. Brain magnetic resonance angiography and transfemoral cerebral angiography revealed complete occlusion of the right middle cerebral artery. Mycoplasma pneumoniae infection was identified by a 4-fold increase in IgG antibodies...
Source: Korean Journal of Pediatrics - May 20, 2016 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

A nationwide study of children and adolescents with pneumonia who visited Emergency Department in South Korea in 2012.
CONCLUSION: Despite the limited data due to the ED data from the NEDIS lacking laboratory results and treatment information, this study reflects well the outbreak patterns among children and adolescents with pneumonia. Our results provide a basis for future studies regarding ED treatment for children and adolescents with pneumonia. PMID: 27186220 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 20, 2016 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Antibiotic resistance of Streptococcus pneumoniae, isolated from nasopharynx of preschool children with acute respiratory tract infection in Lithuania
Increasing pneumococcal resistance to commonly used antibiotics and multidrug resistance is a serious public health concern. Data on distribution of resistant Streptococcus pneumoniae (SPn) strains among children... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - May 20, 2016 Category: Infectious Diseases Authors: Indrė Stacevičienė, Sigita Petraitienė, Daiva Vaičiūnienė, Tomas Alasevičius, Jūratė Kirslienė and Vytautas Usonis Source Type: research

Genome-wide analysis of the transcriptional response to porcine reproductive and respiratory syndrome virus infection at the maternal/fetal interface and in the fetus
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnant pigs can result in congenital infection and ultimately fetal death. Little is known about immune responses to infection at the ... (Source: BMC Genomics)
Source: BMC Genomics - May 20, 2016 Category: Genetics & Stem Cells Authors: Jamie M. Wilkinson, Hua Bao, Andrea Ladinig, Linjun Hong, Paul Stothard, Joan K. Lunney, Graham S. Plastow and John C. S. Harding Source Type: research

High-flow nasal cannula oxygen therapy versus noninvasive ventilation in immunocompromised patients with acute respiratory failure: an observational cohort study
Acute respiratory failure is the main cause of admission to intensive care unit in immunocompromised patients. In this subset of patients, the beneficial effects of noninvasive ventilation (NIV) as compared to... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - May 20, 2016 Category: Intensive Care Authors: Rémi Coudroy, Angéline Jamet, Philippe Petua, René Robert, Jean-Pierre Frat and Arnaud W. Thille Source Type: research

The Apoe−/− mouse model: a suitable model to study cardiovascular and respiratory diseases in the context of cigarette smoke exposure and harm reduction
Atherosclerosis-prone apolipoprotein E-deficient (Apoe−/−) mice display poor lipoprotein clearance with subsequent accumulation of cholesterol ester-enriched particles in the blood, which promote the development ... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 20, 2016 Category: Research Authors: Giuseppe Lo Sasso, Walter K. Schlage, Stéphanie Boué, Emilija Veljkovic, Manuel C. Peitsch and Julia Hoeng Source Type: research

Retinopathy of prematurity in Korean infants with birthweight greater than 1500 g
Conclusion Our study confirmed that treatment-requiring ROP does occur in infants with BW >1500 g. To avoid overlooking infants with vision-threatening ROP, an evaluation of the data from larger BW preterm infants is advisable so that screening guidelines in neonatal care units may be refined. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 20, 2016 Category: Opthalmology Authors: Park, S. H., Yum, H. R., Kim, S., Lee, Y. C. Tags: Paediatrics, Ophthalmologic surgical procedures, Retina, Epidemiology Original articles - Clinical science Source Type: research

Respiratory sinus arrhythmia as a predictor of self-injurious thoughts and behaviors among adolescents
Publication date: Available online 20 May 2016 Source:International Journal of Psychophysiology Author(s): Madeline D. Wielgus, Jaclyn T. Aldrich, Amy H. Mezulis, Sheila E. Crowell Research suggests that self-injurious thoughts and behaviors (SITBs) may function as maladaptive emotion regulation strategies. One psychophysiological index of emotion regulatory capacity is respiratory sinus arrhythmia (RSA). The temporal course of RSA responsivity to a stressor may be characterized by basal RSA, RSA reactivity to stressor, and RSA recovery post-stressor. RSA has been linked to both internalizing and externalizing sympto...
Source: International Journal of Psychophysiology - May 20, 2016 Category: Psychiatry & Psychology Source Type: research

The influence of a low air pressure environment on human metabolic rate during short‐term (< 2 h) exposures
Abstract Passengers in aircraft cabins are exposed to low‐pressure environments. One of the missing links in the research on thermal comfort under cabin conditions is the influence of low air pressure on the metabolic rate. In this research, we simulated the cabin pressure regime in a chamber in which the pressure level could be controlled. Three pressure levels (101/85/70 kPa) were tested to investigate how metabolic rate changed at different pressure levels. The results show that as pressure decreased, the respiratory flow rate (RFR) at standard condition (STPD: 0°C, 101 kPa) significantly decreased. Yet the oxygen (O...
Source: Indoor Air - May 20, 2016 Category: Occupational Health Authors: W. Cui, H. Wang, T. Wu, Q. Ouyang, S. Hu, Y. Zhu Tags: Original Article Source Type: research

DCD liver transplant infection: experience from a single centre in China
ConclusionThis is the first study that offers detailed data revealing the timing and incidence of bacterial and fungal infection among adult DCD liver transplant recipients. Bacterial and fungal infection occurs at a high rate during the first week after DCD liver transplant, especially in patients with prolonged respiratory support time and renal failure, and infection is related to increased hospital stay. (Source: International Journal of Clinical Practice)
Source: International Journal of Clinical Practice - May 20, 2016 Category: Internal Medicine Authors: Z. Tu, P. Xiang, X. Xu, L. Zhou, L. Zhuang, J. Wu, W. Wang, S. Zheng Tags: Original Paper Source Type: research

Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent
Ko & Christian L Lorson (Source: Molecular Therapy)
Source: Molecular Therapy - May 20, 2016 Category: Genetics & Stem Cells Authors: Monir ShababiZhihua FengEric VillalonChristine M SibigtrothErkan Y OsmanMadeline R MillerPatricka A Williams-SimonAbby LombardiThalia H SassArleigh K AtkinsonMichael L GarciaChien-Ping KoChristian L Lorson Source Type: research

IJERPH, Vol. 13, Pages 514: Knowledge and Perceptions about Nicotine, Nicotine Replacement Therapies and Electronic Cigarettes among Healthcare Professionals in Greece
Conclusions. Greek healthcare professionals appear to overestimate the adverse effects of nicotine, and many would not recommend any nicotine-containing product as a long-term smoking substitute. Additionally, they have poor knowledge about the function and characteristics of electronic cigarettes. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - May 20, 2016 Category: Environmental Health Authors: Anastasia MoysidouKonstantinos FarsalinosVassilis VoudrisKyriakoula MerakouKallirrhoe KoureaAnastasia Barbouni Tags: Article Source Type: research

Preparation of purified perikaryal and synaptosomal mitochondrial fractions from relatively small hypothalamic brain samples
Publication date: Available online 19 May 2016 Source:MethodsX Author(s): David S. Kiss, Istvan Toth, Gergely Jocsak, Agnes Sterczer, Tibor Bartha, Laszlo V. Frenyo, Attila Zsarnovszky In order to measure the activity of neuronal mitochondria, a representative proof of neuronal processes, physiologically relevant mitochondrial samples need to be gained as simply as possible. Existing methods are, however, either for tissue samples of large size and/or homogenous microstructures only, or are not tested for mitochondrial function measurements. In the present article we describe a gradient fractionation method to iso...
Source: MethodsX - May 20, 2016 Category: Science Source Type: research

Augmentation of the Lesser Curvature With an Autologous Vascular Patch in Complex Aortic Coarctation and Interruption
Conclusions Augmenting the lesser curvature with an autologous vascular patch during arch reconstruction resulted in excellent midterm outcomes. Not only can a more natural shape of arch and less tension on the anastomosis be obtained, but complications, such as left main bronchial obstruction or recoarctation, can also be minimized. Long-term follow-up is needed to evaluate late development of recoarctation, hypertension, or aneurysm formation. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 20, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Double epigenetic modulation of high‐dose chemotherapy with azacitidine and vorinostat for patients with refractory or poor‐risk relapsed lymphoma
CONCLUSIONSDouble epigenetic modulation of Gem/Bu/Mel with azacitidine/vorinostat is feasible and highly active in patients with refractory/poor‐risk relapsed lymphomas, warranting further evaluation. Cancer 2016. © 2016 American Cancer Society. (Source: Cancer)
Source: Cancer - May 20, 2016 Category: Cancer & Oncology Authors: Yago Nieto, Benigno C. Valdez, Peter F. Thall, Roy B. Jones, Wei Wei, Alan Myers, Chitra Hosing, Sairah Ahmed, Uday Popat, Elizabeth J. Shpall, Muzaffar Qazilbash, Alison Gulbis, Paolo Anderlini, Nina Shah, Qaiser Bashir, Amin Alousi, Yasuhiro Oki, Michel Tags: Original Article Source Type: research

Response to Letter to the Editor: ‘High-frequency percussive ventilation and initial biomarker levels of lung injury after smoke inhalation – Not straightforward to interpret’
We thank R.S. Shah, M. Vizacaychipis for their thoughts about the published work and would like to describe some important points about our study of biomarkers following high frequency percussive ventilation in patients with acute respiratory failure following inhalation injury without extensive burns [1]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - May 20, 2016 Category: Cosmetic Surgery Authors: P. Reper, W. Heijmans Tags: Reply to Letter to the Editor Source Type: research