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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

The Six-Minute Stepper Test: Solvitur ambulando
Respiration (Source: Respiration)
Source: Respiration - June 21, 2016 Category: Respiratory Medicine Source Type: research

Functional Characterization of Patients with Chronic Thromboembolic Disease
This study aimed to analyze the exercise capacity and limiting factors in CTED. Methods: We compared right heart catheterization and cardiopulmonary exercise test results of patients with CTED [mean pulmonary artery pressure (mPAP) at rest (Source: Respiration)
Source: Respiration - June 21, 2016 Category: Respiratory Medicine Source Type: research

Painful Oral Ulcers With Lymphadenopathy and Respiratory Symptoms: Challenge
No abstract available (Source: The American Journal of Dermatopathology)
Source: The American Journal of Dermatopathology - June 21, 2016 Category: Pathology Tags: Clinical Pathologic Challenge Source Type: research

Painful Oral Ulcers With Lymphadenopathy and Respiratory Symptoms
No abstract available (Source: The American Journal of Dermatopathology)
Source: The American Journal of Dermatopathology - June 21, 2016 Category: Pathology Tags: Clinical Pathologic Challenge Answer Source Type: research

Underestimation of homeless clients.
Conclusions: Many smokers using homeless services want to quit and are actively trying to reduce and quit smoking. Smoking-cessation assistance that meets the needs of people experiencing homelessness is clearly warranted.So what?: Homeless services should develop, and include in their smoking policy and intake processes, a practice of routinely assessing tobacco use, offering brief interventions and referral to appropriately tailored services. PMID: 27321708 [PubMed - as supplied by publisher] (Source: Health Promotion Journal of Australia)
Source: Health Promotion Journal of Australia - June 21, 2016 Category: Global & Universal Tags: Health Promot J Austr Source Type: research

Effect of Mechanical Ventilation Mode Type on Intra- and Postoperative Blood Loss in Patients Undergoing Posterior Lumbar Interbody Fusion Surgery A Randomized Controlled Trial
Conclusion Intraoperative PCV decreased intraoperative surgical bleeding in patients undergoing PLIF, which may be related to lower intraoperative peak inspiratory pressure. (Source: Anesthesiology)
Source: Anesthesiology - June 21, 2016 Category: Anesthesiology Source Type: research

Continuous Positive Airway Pressure Mitigates Opioid-induced Worsening of Sleep-disordered Breathing Early after Bariatric Surgery
Conclusions This pharmacophysiologic interaction trial shows that supervised CPAP treatment early after surgery improves SDB and ameliorates the respiratory-depressant effects of opioids without undue hemodynamic effects. (Source: Anesthesiology)
Source: Anesthesiology - June 21, 2016 Category: Anesthesiology Source Type: research

Control of Respiratory Drive and Effort in Extracorporeal Membrane Oxygenation Patients Recovering from Severe Acute Respiratory Distress Syndrome
Conclusions In patients recovering from ARDS undergoing ECMO, the amount of carbon dioxide removed by the artificial lung may influence spontaneous breathing. The effects of carbon dioxide removal on spontaneous breathing during the earlier acute phases of ARDS remain to be elucidated. (Source: Anesthesiology)
Source: Anesthesiology - June 21, 2016 Category: Anesthesiology Source Type: research

Efficacy and safety of SQ house dust mite (HDM) SLIT-tablet treatment of HDM allergic asthma.
Authors: Canonica GW, Virchow JC, Zieglmayer P, Ljørring C, Smith IM, Mosbech H Abstract INTRODUCTION: In the treatment of house dust mite (HDM) respiratory allergic disease, allergy immunotherapy constitutes an add-on treatment option targeting the underlying immunological mechanisms of allergic disease. However, for the treatment of HDM allergic asthma, the use of subcutaneous allergy immunotherapy (SCIT) has been limited by the risk of systemic adverse events. Thus, sublingually administered allergy immunotherapy (SLIT) has been investigated as a treatment option with an improved tolerability profile that allow...
Source: Expert Review of Clinical Immunology - June 21, 2016 Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research

Helmets trump face mask for noninvasive ventilation
Treating acute respiratory distress syndrome patients with helmets instead of face masks significantly reduced intubation rates and 90-day mortality rates, based on data from a randomized trial of 83... (Source: Internal Medicine News)
Source: Internal Medicine News - June 21, 2016 Category: Internal Medicine Source Type: research

Helmets trump face mask for noninvasive ventilation
Treating acute respiratory distress syndrome patients with helmets instead of face masks significantly reduced intubation rates and 90-day mortality rates, based on data from a randomized trial of 83... (Source: Hospitalist News)
Source: Hospitalist News - June 21, 2016 Category: Hospital Management Source Type: research

Respiratory Complication in Liver Disease
This article reviews these complications. (Source: Critical Care Clinics)
Source: Critical Care Clinics - June 21, 2016 Category: Intensive Care Authors: Vijaya S. Ramalingam, Sikandar Ansari, Micah Fisher Source Type: research

Pseudomonas aeruginosa resistance patterns and clinical outcomes in hospitalized exacerbations of COPD
ConclusionPseudomonas aeruginosa‐resistant affects patients with severe AECOPD and previous use of corticosteroids and antibiotics. The presence of PA‐S is associated with higher mortality. These results may suggest increased virulence in PA‐S strains causing acute infections. (Source: Respirology)
Source: Respirology - June 21, 2016 Category: Respiratory Medicine Authors: Ana Rodrigo‐Troyano, Guillermo Suarez‐Cuartin, Meritxell Peiró, Silvia Barril, Diego Castillo, Ferran Sanchez‐Reus, Vicente Plaza, Marcos I. Restrepo, James D. Chalmers, Oriol Sibila Tags: Original Article Source Type: research

Persistence of Antibodies against Middle East Respiratory Syndrome Coronavirus
D. C. Payne et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - June 21, 2016 Category: Infectious Diseases Source Type: research

Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology
Diagnosis of acute lung allograft rejection is currently based on transbronchial lung biopsies. Additional methods to detect acute allograft dysfunction derived from plasma and bronchoalveolar lavage samples m... (Source: Respiratory Research)
Source: Respiratory Research - June 21, 2016 Category: Respiratory Medicine Authors: Nicole E. Speck, Macé M. Schuurmans, Christian Murer, Christian Benden and Lars C. Huber Source Type: research

Alternate circulation and genetic variation of human respiratory syncytial virus genotypes in Chengdu, West China, 2009‐2014
This study elucidated the local HRSV epidemic was associated with the alternate circulation of multiple genotypes and with the change of glycosylation sites of G protein. This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)
Source: Journal of Medical Virology - June 21, 2016 Category: Virology Authors: Peng‐Wei Hu, Tian‐Li Zheng, Jia‐Yi Chen, Tao Zhou, Yu‐Hang Chen, Xin Xu, Xiao‐Fang Pei Tags: Research Article Source Type: research

IJERPH, Vol. 13, Pages 613: Association between Ambient Air Pollution and Emergency Room Visits for Respiratory Diseases in Spring Dust Storm Season in Lanzhou, China
Conclusions: This study strengthens the evidence of dust-exacerbated ER visits for respiratory diseases in Lanzhou. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - June 21, 2016 Category: Environmental Health Authors: Yuxia MaBingshuang XiaoChang LiuYuxin ZhaoXiaodong Zheng Tags: Article Source Type: research

Age range for inclusion affects ascertainment by birth defects registers
ConclusionThis study highlights the value of birth defect registers collecting information about birth defects from terminations of pregnancy, stillbirths, and live births up to a child's fifth birthday. Reviewing diagnosis date provides insight into the pattern of diagnosis of different birth defects. This provides valuable information to medical specialists and researchers regarding the interpretation of information from birth defect data collections. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc. (Source: Birth Defects Research Part A: Clinical and Molecular Teratology)
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - June 21, 2016 Category: Perinatology & Neonatology Authors: Catherine S. Gibson, Heather Scott, Eric Haan, Wendy Scheil Tags: Original Research Article Source Type: research

T2-prepared velocity selective labelling: A novel idea for full-brain mapping of oxygen saturation
Discussion/conclusion Full brain SO2 assessment by any technique may help validating NIRS and may prove useful in guiding the clinical management of patient populations with cerebral injury following hypoxic-ischaemic events. The agreement between NIRS and T2-BIOS provides confidence in measuring cerebral SO2 by either technique. As it stands now, the T2-BIOS represents a novel idea and future work will focus on improvements to make it a reliable tool for SO2 assessment. (Source: NeuroImage)
Source: NeuroImage - June 21, 2016 Category: Neuroscience Source Type: research

The respiratory DC/macrophage network at steady-state and upon influenza infection in the swine biomedical model
The respiratory DC/macrophage network at steady-state and upon influenza infection in the swine biomedical model Mucosal Immunology 9, 835 (July 2016). doi:10.1038/mi.2015.105 Authors: P Maisonnasse, E Bouguyon, G Piton, A Ezquerra, C Urien, C Deloizy, M Bourge, J-J Leplat, G Simon, C Chevalier, S Vincent-Naulleau, E Crisci, M Montoya, I Schwartz-Cornil & N Bertho (Source: Mucosal Immunology)
Source: Mucosal Immunology - June 21, 2016 Category: Allergy & Immunology Authors: P MaisonnasseE BouguyonG PitonA EzquerraC UrienC DeloizyM BourgeJ-J LeplatG SimonC ChevalierS Vincent-NaulleauE CrisciM MontoyaI Schwartz-CornilN Bertho Source Type: research

Spatiotemporal interplay of severe acute respiratory syndrome coronavirus and respiratory mucosal cells drives viral dissemination in rhesus macaques
A Lackner & Z Chen (Source: Mucosal Immunology)
Source: Mucosal Immunology - June 21, 2016 Category: Allergy & Immunology Authors: L LiuQ WeiK NishiuraJ PengH WangC MidkiffX AlvarezC QinA LacknerZ Chen Source Type: research

The Effect of Transcutaneous Electrical Nerve Stimulation in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Randomized Controlled Trial
ConclusionAdding TENS therapy to pharmacotherapy in patients with AECOPD provided clinical improvement in FEV1 and add benefit in exercise capacity, but no significant effect on the other outcomes measured. Relevance to clinical practiceTENS can be used as a non‐invasive complementary therapy due to its beneficial effects on FEV1 and exercise capacity in patients with AECOPD.This article is protected by copyright. All rights reserved. (Source: Journal of Clinical Nursing)
Source: Journal of Clinical Nursing - June 21, 2016 Category: Nursing Authors: Emine Öncü, Handan Zincir Tags: Original Article Source Type: research

Multidisciplinary treatment for prepubertal juvenile myasthenia gravis with crisis
We report herein the case of a 12‐year‐old girl with prepubertal juvenile MG with respiratory crisis who underwent thymectomy following methylprednisolone pulse therapy. The patient initially developed progressively worsening fatigability, eyelid ptosis, and diplopia, followed by worsening generalized weakness, dysphagia, and dyspnea. Even after i.v. immunoglobulin, the patient presented with rapid onset of severe dyspnea requiring respiratory support with mechanical ventilation and was graded as Myasthenia Gravis Foundation of America class V. After a course of i.v. methylprednisolone pulse therapy, successful control...
Source: Pediatrics International - June 21, 2016 Category: Pediatrics Authors: Yusuke Hirata, Masayoshi Inoue, Shin Nabatame, Meinoshin Okumura, Keiichi Ozono Tags: Patient Report Source Type: research

Importance of high sensitivity C‐reactive protein in the evaluation of wheezing in children
ConclusionsHigh‐sensitivity CRP can be used to indicate respiratory and systemic inflammation independently of mAPI positivity in wheezy children. (Source: Pediatrics International)
Source: Pediatrics International - June 21, 2016 Category: Pediatrics Authors: Ilknur Bostanci, Serap Ozmen, Hilal Susam Sen, Emine Misirlioglu Dibek, Pelin Zorlu Tags: Original Article Source Type: research

A rare case of esophageal lung in a neonate
We report a rare case of esophageal lung in a neonate who presented with repeated chest infections and respiratory distress. Chest radiograph revealed increased opacification of the right lung with reduced lung volume and air bronchograms. Further evaluation with computed tomography (CT) showed the presence of only left mainstem bronchus at the tracheal bifurcation. Right mainstem bronchus originated from distal esophagus and aerated the right lung. Nasogastric tube was inserted into the stomach with injection of small amount of dilute barium through it, which established the communication of right mainstem bronchus with e...
Source: Indian Journal of Radiology and Imaging - June 21, 2016 Category: Radiology Authors: Megharanjini PatilJagadish SutagattiMohan BhavikattiPuneet V Nayak Source Type: research

Assessment of bariatric surgery efficacy on Obstructive Sleep Apnea (OSA)
In conclusion, bariatric surgery has a significant effect on OSA, leading to its resolution or improvement, in the majority of cases, at least in the short/medium term (1–2 years). However, the different results must be interpreted with caution as there are many potential biases resulting from heterogeneous inclusion criteria, duration of follow-up, diagnostic methodology and assessed variables. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - June 21, 2016 Category: Respiratory Medicine Source Type: research

Transport and Deposition of Welding Fume Agglomerates in a Realistic Human Nasal Airway
Welding fume is a complex mixture containing ultra-fine particles in the nanometer range. Rather than being in the form of a singular sphere, due to the high particle concentration, welding fume particles agglomerate into long straight chains, branches, or other forms of compact shapes. Understanding the transport and deposition of these nano-agglomerates in human respiratory systems is of great interest as welding fumes are a known health hazard. The neurotoxin manganese (Mn) is a common element in welding fumes. Particulate Mn, either as soluble salts or oxides, that has deposited on the olfactory mucosa in human nasal a...
Source: Annals of Occupational Hygiene - June 21, 2016 Category: Occupational Health Authors: Tian, L., Inthavong, K., Liden, G., Shang, Y., Tu, J. Tags: Original Article Source Type: research

Efficiency of Respirator Filter Media against Diesel Particulate Matter: A Comparison Study Using Two Diesel Particulate Sources
This study examined filtering efficiency for three commonly used AS/NZS certified respirator filter models, challenging them with two types of diesel emissions; those from a diesel generator and a diesel engine. Penetration through the filter media of elemental carbon (EC), total carbon (TC), and total suspended particulate (TSP) was calculated. Results indicate that filtering efficiency assumed by P2 certification in Australia was achieved for two of the three respirator models for DPM generated using the small diesel generator, whilst when the larger diesel engine was used, filtering efficiency requirements were met for ...
Source: Annals of Occupational Hygiene - June 21, 2016 Category: Occupational Health Authors: Burton, K. A., Whitelaw, J. L., Jones, A. L., Davies, B. Tags: Original Article Source Type: research

Stereotactic body radiotherapy for T3 and T4N0M0 non-small cell lung cancer
To evaluate the outcomes and feasibility of stereotactic body radiotherapy (SBRT) for cT3 and cT4N0M0 non–small cell lung cancer (NSCLC), 25 patients with localized primary NSCLC diagnosed as cT3 or cT4N0M0, given SBRT between May 2005 and July 2013, were analyzed. All patients had inoperable tumors. The major reasons for tumors being unresectable were insufficient respiratory function for curative resection, advanced age (>80 years old) or technically inoperable due to invasion into critical organs. The median patient age was 79 years (range; 60–86). The median follow-up duration was 25 months (range: 5&nda...
Source: Journal of Radiation Research - June 21, 2016 Category: Physics Authors: Eriguchi, T., Takeda, A., Sanuki, N., Nishimura, S., Takagawa, Y., Enomoto, T., Saeki, N., Yashiro, K., Mizuno, T., Aoki, Y., Oku, Y., Yokosuka, T., Shigematsu, N. Tags: Regular paper Source Type: research

Association between slow wave activity, cognition and behaviour in children with sleep disordered breathing
• Children originally diagnosed with SDB during early childhood continue to show reduced behavioural and cognitive performance compared to control children three years following complete resolution of disease• Irrespective of severity of original disease, improvements in Slow Wave Activity and the number of respiratory events have concomitant improvements in daytime functioning, although not to control levels• Irrespective of whether SDB completely resolves or not, children whose quantitative sleepiness improved over time have improved sustained attention and a reduction in externalising behaviours (Source: Sleep Medicine)
Source: Sleep Medicine - June 21, 2016 Category: Sleep Medicine Authors: Aidan J Weichard, Lisa M Walter, Samantha L Hollis, Gillian M Nixon, Margot J Davey, Rosemary SC Horne, Sarah N Biggs Tags: Original Article Source Type: research

Computational fluid dynamic study of nasal respiratory function before and after bimaxillary orthognathic surgery with bone trimming at the inferior edge of the pyriform aperture
This study aimed to evaluate the influence of maxillary impaction orthognathic surgery on nasal respiratory function and the efficacy of bone trimming at the inferior edge of the pyriform aperture. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - June 21, 2016 Category: ENT & OMF Authors: Soma Kita, Marie Oshima, Kazuo Shimazaki, Toshinori Iwai, Susumu Omura, Takashi Ono Source Type: research

Prevalence of Comorbidities in the Middle East Respiratory Syndrome Coronavirus (MERS-CoV): A Systematic Review and Meta-analysis
(Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - June 21, 2016 Category: Infectious Diseases Authors: Alaa Badawi, Seung Gwan Ryoo Source Type: research

Abdominal massage may decrease gastric residual volumes and abdominal circumference in critically ill patients
Commentary on: Kahraman BB, Ozdemir L. The impact of abdominal massage administered to intubated and enterally fed patients on the development of ventilator-associated pneumonia: a randomized controlled study. Int J Nurs Stud 2015;52:519–24. Implications for practice and research Abdominal massage may decrease gastric residual volumes (GRVs) and abdominal circumference over time in a select medicine critical care unit population. Research and standardisation for the practice of abdominal massage may provide clinicians additional tools for improving overall gastrointestinal (GI) function and feeding in the critically ...
Source: Evidence-Based Nursing - June 21, 2016 Category: Nursing Authors: Warren, M. Tags: Adult nursing, Pneumonia (infectious disease), TB and other respiratory infections, Obesity (nutrition), Pneumonia (respiratory medicine), Health education, Obesity (public health) Source Type: research

Nasal balloon autoinflation can help clear middle ear effusion, improving the quality of life in school-aged children with glue ear
Commentary on: Williamson I, Vennik J, Harnden A, et al.. An open randomised study of autoinflation in 4- to 11-year-old school children with otitis media with effusion in primary care. Health Technol Assess 2015;19:1–150. Implications for practice and research Autoinflation with a nasal balloon can improve symptoms and clear middle ear effusion (MEE) in school-aged children with recent onset of glue ear. Further research is required to determine whether nasal balloon autoinflation reduces the need for grommet surgery. Context Otitis media with effusion, commonly known as glue ear, is the most common cause of hearing...
Source: Evidence-Based Nursing - June 21, 2016 Category: Nursing Authors: Schilder, A. G. M., Venekamp, R. P. Tags: Health policy, General practice / family medicine, Child health, Immunology (including allergy), Otitis, TB and other respiratory infections, Pain (neurology), Child health, Ear, nose and throat/otolaryngology, Health service research Source Type: research

Confirming nasogastric tube placement: Is the colorimeter as sensitive and specific as X-ray? A diagnostic accuracy study
The effect of delivering enteral nutrition or medications via a nasogastric tube that is inadvertently located in the tracheobronchial tract can cause respiratory complications. Although radiographic examination is accepted as the gold standard for confirming the position of patients’ enteral tubes, it is costly, involves risks of radiation, and is not failsafe. Studies using carbon dioxide sensors to detect inadvertent nasogastric tube placements have been conducted in intensive care settings. However, none involved patients in general wards. (Source: International Journal of Nursing Studies)
Source: International Journal of Nursing Studies - June 21, 2016 Category: Nursing Authors: Siti Zubaidah Mordiffi, Mien Li Goh, Jason Phua, Yiong-Huak Chan Source Type: research

Individualized lung recruitment during high-frequency ventilation in preterm infants is not associated with lung hyperinflation and air leaks
Conclusion: The risk of significant hyperinflation and air leaks is low when using an individualized oxygenation-guided recruitment procedure during HFV in preterm infants with RDS. What is Known: • Lung recruitment during high-frequency ventilation in preterm infants with respiratory distress syndrome is associated with an increased risk of lung hyperinflation and air leaks. What is New: ...
Source: European Journal of Pediatrics - June 21, 2016 Category: Pediatrics Source Type: research

Bone health and disease in cystic fibrosis
Low bone mineral density is common in children and adults with CF. It has a multifactorial aetiology that includes direct effects of CFTR dysfunction on bone cell activity, as well as the secondary effects of CFTR dysfunction including pancreatic insufficiency (leading to malnutrition/malabsorption of fat soluble vitamins) and pulmonary infection (leading to systemic inflammation and increased bone resorption). Strategies to improve bone health in CF include optimising general CF nutritional and pulmonary care and the judicious use of bisphosphonates in selected patients. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - June 21, 2016 Category: Respiratory Medicine Authors: Malcolm Marquette, Charles S. Haworth Source Type: research

Relationships between emphysema and airways metrics at high-resolution computed tomography (HRCT) and ventilatory response to exercise in mild to moderate COPD patients
In Chronic Obstructive Pulmonary Disease (COPD) patients, the opportunity to carry out a thoracic high-resolution CT (HRCT) scan and to perform an incremental cardiopulmonary exercise test (CPET) increases the possibility to identify the different clinical features of disease. The aim of our study was to evaluate the relationships between HRCT metrics (on emphysema by low attenuation areas-LAA% and airways by wall area-WA%) and CPET variables related to the dynamic response to exercise in terms of elastic balance (Δ rest-to-peak IC/TLC) and ventilation capacity for carbon dioxide output (VE/VCO2 slope and VE/VCO2 intercep...
Source: Respiratory Medicine CME - June 21, 2016 Category: Respiratory Medicine Authors: Ernesto Crisafulli, Veronica Alfieri, Mario Silva, Marina Aiello, Panagiota Tzani, Gianluca Milanese, Giuseppina Bertorelli, Nicola Sverzellati, Alfredo Chetta Source Type: research

A novel guluronate oligomer improves intestinal transit and survival in cystic fibrosis mice
Cystic fibrosis (CF) patients experience intestinal complications characterized by the accumulation of thick viscous mucus. CF mice were utilized to determine if a novel guluronate oligomer, OligoG, may be a potential therapy in reducing intestinal mucus and subsequent CF-related intestinal manifestations. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - June 21, 2016 Category: Respiratory Medicine Authors: Megan Vitko, Dana M. Valerio, Philip D. Rye, Edvar Onsøyen, Astrid H. Myrset, Arne Dessen, Mitchell L. Drumm, Craig A. Hodges Tags: Original Article Source Type: research

Objective airway artery dimensions compared to CT scoring methods assessing structural cystic fibrosis lung disease
CF-CT and PRAGMA-CF are commonly used scoring methods to quantify the severity of bronchiectasis (BE) and airway wall thickening (AWT) on chest CTs of children with cystic fibrosis (CF). We aimed to validate CF-CT and PRAGMA-CF sub-scores for BE and AWT against quantitative airway–artery (AA) dimensions. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - June 21, 2016 Category: Respiratory Medicine Authors: Wieying Kuo, Eleni-Rosalina Andrinopoulou, Adria Perez-Rovira, Hadiye Ozturk, Marleen de Bruijne, Harm H.A.W.M. Tiddens Tags: Original Article Source Type: research

[Hidden allergens in processed food : An update from the consumer's point of view].
Abstract Despite improved allergen labelling and careful avoidance strategies, hidden allergens in food remain a substantial risk for unintended reactions for consumers with food allergies. New data from a survey of the German Allergy and Asthma Association (Deutscher Allergie- und Asthmabund - DAAB) shows a slight decrease in the number of consumers that report allergic reactions to prepacked food. Still, 75 % (compared to 85 % in 2008) have experienced at least one allergic reaction after eating a prepacked food. In more than half of the cases, the reaction was classified as severe (with airway and/or car...
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - June 21, 2016 Category: Global & Universal Authors: Schnadt S, Pfaff S Tags: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Source Type: research

Comparing Use of Low-Value Health Care Services Among U.S. Advanced Practice Clinicians and Physicians.
Conclusion: APCs and physicians provided an equivalent amount of low-value health services, dispelling physicians' perceptions that APCs provide lower-value care than physicians for these common conditions. Primary Funding Source: U.S. Health Services and Research Administration, Ryoichi Sasakawa Fellowship Fund, and National Institutes of Health. PMID: 27322541 [PubMed - as supplied by publisher] (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - June 21, 2016 Category: Internal Medicine Authors: Mafi JN, Wee CC, Davis RB, Landon BE Tags: Ann Intern Med Source Type: research

Corneal toxicity induced by vesicating agents and effective treatment options
The vesicating agents sulfur mustard (SM) and lewisite (LEW) are potent chemical warfare agents that primarily cause damage to the ocular, skin, and respiratory systems. However, ocular tissue is the most sensitive organ, and vesicant exposure results in a biphasic injury response, including photophobia, corneal lesions, corneal edema, ulceration, and neovascularization, and may cause loss of vision. There are several reports on ocular injury from exposure to SM, which has been frequently used in warfare. However, there are very few reports on ocular injury by LEW, which indicate that injury symptoms appear instantly after...
Source: Annals of the New York Academy of Sciences - June 21, 2016 Category: Science Authors: Dinesh G. Goswami, Neera Tewari‐Singh, Rajesh Agarwal Tags: Original Article Source Type: research

Cd(2+) extrusion by P-type Cd(2+)-ATPase of Staphylococcus aureus 17810R via energy-dependent Cd(2+)/H(+) exchange mechanism.
Abstract Cd(2+) is highly toxic to Staphylococcus aureus since it blocks dithiols in cytoplasmic 2-oxoglutarate dehydrogenase complex (ODHC) participating in energy conservation process. However, S. aureus 17810R is Cd(2+)-resistant due to possession of cadA-coded Cd(2+) efflux system, recognized here as P-type Cd(2+)-ATPase. This Cd(2+) pump utilizing cellular energy-ATP, ∆μ H (+) (electrochemical proton potential) and respiratory protons, extrudes Cd(2+) from cytoplasm to protect dithiols in ODHC, but the mechanism of Cd(2+) extrusion remains unknown. Here we propose that two Cd(2+) taken up by strain 17810R v...
Source: Biometals - June 21, 2016 Category: Biochemistry Authors: Tynecka Z, Malm A, Goś-Szcześniak Z Tags: Biometals Source Type: research

Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction.
Abstract The loss of strength in combination with constant fatigue is a burden on cancer patients undergoing chemotherapy. Doxorubicin, a standard chemotherapy drug used in the clinic, causes skeletal muscle dysfunction and increases mitochondrial H2O2 We hypothesized the combined effect of cancer and chemotherapy in an immunocompetent breast cancer mouse model (E0771) would compromise skeletal muscle mitochondrial respiratory function, leading to an increase in H2O2 emitting potential and impaired muscle function. Here we demonstrate cancer chemotherapy decreases mitochondrial respiratory capacity supported with c...
Source: Am J Physiol Endocri... - June 21, 2016 Category: Endocrinology Authors: Gilliam LA, Lark DS, Reese LR, Torres MJ, Ryan TE, Lin CT, Cathey BL, Neufer PD Tags: Am J Physiol Endocrinol Metab Source Type: research