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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

A questionnaire to measure medical students' attitudes towards occupational medicine
Conclusions This questionnaire can be used to measure attitude towards occupational medicine; however, this questionnaire needs to be developed further. (Source: Occupational Medicine)
Source: Occupational Medicine - July 17, 2015 Category: Respiratory Medicine Authors: Smits, P. B. A., Verbeek, J. H. A. M. Tags: Health information and reporting Original Paper Source Type: research

Intensification and isolation: psychosocial work environment changes in Spain 2005-10
Conclusions There has been an intensification of work, reduction in social support and a notable increase in exposure to high strain and iso-strain. The class inequalities reflect the segmentation of the Spanish labour market. (Source: Occupational Medicine)
Source: Occupational Medicine - July 17, 2015 Category: Respiratory Medicine Authors: Utzet, M., Navarro, A., Llorens, C., Moncada, S. Tags: Occupational stress Original Paper Source Type: research

Risk-taking behaviours among UK military reservists
Conclusions It is important to consider the impact of deployment and military factors on the prevalence of risk-taking behaviours in reservists as greater numbers than ever before will face the prospect of deployment to overseas conflicts. (Source: Occupational Medicine)
Source: Occupational Medicine - July 17, 2015 Category: Respiratory Medicine Authors: Thandi, G., Sundin, J., Dandeker, C., Jones, N., Greenberg, N., Wessely, S., Fear, N. T. Tags: Military - Mental Health, Military - Fitness for Work Original Paper Source Type: research

Unexpected pharmacological and toxicological effects of tafenoquine
(Source: Occupational Medicine)
Source: Occupational Medicine - July 17, 2015 Category: Respiratory Medicine Authors: Nevin, R. L. Tags: Chemicals Letter to the Editor Source Type: research

Addenbrooke's Cognitive Examination-III
(Source: Occupational Medicine)
Source: Occupational Medicine - July 17, 2015 Category: Respiratory Medicine Authors: Noone, P. Tags: Questionnaire Review Source Type: research

Disability and Equity at Work
(Source: Occupational Medicine)
Source: Occupational Medicine - July 17, 2015 Category: Respiratory Medicine Authors: Bray, A. Tags: Book Review Source Type: research

Epidemiology
(Source: Occupational Medicine)
Source: Occupational Medicine - July 17, 2015 Category: Respiratory Medicine Authors: Smedley, J. Tags: Book Review Source Type: research

Occupational Medicine Calendar
(Source: Occupational Medicine)
Source: Occupational Medicine - July 17, 2015 Category: Respiratory Medicine Tags: Calendar Source Type: research

Fungal DNA in dust in Swedish day care centres: associations with respiratory symptoms, fractional exhaled nitrogen oxide (FeNO) and C-reactive protein (CRP) in serum among day care centre staff
Conclusion Fungal contamination in day care centres, measured as fungal DNA, can be a risk factor for airway inflammation, and CRP is associated with BMI. (Source: International Archives of Occupational and Environmental Health)
Source: International Archives of Occupational and Environmental Health - July 17, 2015 Category: Occupational Health Source Type: research

IJERPH, Vol. 12, Pages 8359-8412: Climate Change, Drought and Human Health in Canada
Droughts have been recorded all across Canada and have had significant impacts on individuals and communities. With climate change, projections suggest an increasing risk of drought in Canada, particularly in the south and interior. However, there has been little research on the impacts of drought on human health and the implications of a changing climate. A review of the Canadian, U.S. and international literature relevant to the Canadian context was conducted to better define these impacts and adaptations available to protect health. Drought can impact respiratory health, mental health, illnesses related to exposure to t...
Source: International Journal of Environmental Research and Public Health - July 17, 2015 Category: Environmental Health Authors: Anna YusaPeter BerryJune J.ChengNicholas OgdenBarrie BonsalRonald StewartRuth Waldick Tags: Review Source Type: research

Association of the presence of influenza A virus and porcine reproductive and respiratory syndrome virus in sow farms with post-weaning mortality
Publication date: Available online 17 July 2015 Source:Preventive Veterinary Medicine Author(s): Julio Alvarez, Javier Sarradell, Barry Kerkaert, Dipankar Bandyopadhyay, Montserrat Torremorell, Robert Morrison, Andres Perez Influenza A virus (IAV) and porcine reproductive and respiratory syndrome virus (PRRSV) are among the most important pathogens affecting pigs worldwide. Their effect on post-weaning mortality can be substantial and may be potentiated by other concomitant factors. Here, the objective was to evaluate the association between IAV and PRRSV infection at weaning with post-weaning mortality observed i...
Source: Preventive Veterinary Medicine - July 17, 2015 Category: Veterinary Research Source Type: research

Innate and adaptive immunity against PRRSV
Publication date: Available online 17 July 2015 Source:Veterinary Immunology and Immunopathology Author(s): Crystal L. Loving, Fernando A. Osorio, Michael P. Murtaugh, Federico A. Zuckermann Many highly effective vaccines have been produced against viruses whose virulent infection elicits strong and durable protective immunity. In these cases, characterization of immune effector mechanisms and identification of protective epitopes/immunogens has been informative for the development of successful vaccine programs. Diseases in which the immune system does not rapidly clear the acute infection and/or convalescent immuni...
Source: Veterinary Immunology and Immunopathology - July 17, 2015 Category: Veterinary Research Source Type: research

Performance of the Alere i Influenza A&B Assay and mariPOC Test for the Rapid Detection of Influenza A and B Viruses
Influenza viruses A and B are major respiratory pathogens with remarkable morbidity and mortality, especially among elderly and immunocompromised subjects. Timely detection of influenza is required to facilitate appropriate patient management, including early administration of antiviral therapy and infection control measures for prevention of nosocomial outbreaks. To realize expectations of sensitive, specific and rapid detection of influenza viruses, several test approaches are available, all of which have their advantages and limitations. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - July 17, 2015 Category: Virology Authors: Pia Jokela, Tytti Vuorinen, Matti Warisb, Raija Manninen Source Type: research

Inflammatory responses to neutral fat and fatty acids in multiple organs in a rat model of fat embolism syndrome
Fat embolism (FE) is fat within the circulation, which can produce embolic phenomena, with or without clinical sequelae [1]. It is generally assumed that the fat is embolized into different organs, notably the lungs [2]. Pulmonary fat embolism (PFE) mainly occurs due to long-bone fractures, but can also occur due to fat crushing [2]. PFE causes acute respiratory distress, and the resulting hypoxia can lead to sudden death. Moreover fat embolism syndrome (FES) is a serious manifestation of FE involving multiple organs and is potentially life threatening [3]. (Source: Forensic Science International)
Source: Forensic Science International - July 17, 2015 Category: Forensic Medicine Authors: Meri Takada, Shoetsu Chiba, Tomonori Nagai, Hiroshi Takeshita, Sanae Kanno, Toru Ikawa, Kana Sakamoto, Morihisa Sagi, Kazue Ichiba, Toshiji Mukai Source Type: research

Analysis of Unexpected Conversion to Thoracotomy During Thoracoscopic Lobectomy in Lung Cancer
Conclusions Unexpected conversion to thoracotomy during VATS lobectomy in lung cancer does not appear to increase overall surgical morbidity and mortality. However, with high-risk patients, the surgeon requires careful selection for VATS candidate. Also, if necessary, the decision to convert must be made promptly to reduce possible critical respiratory complications. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - July 17, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Traumatic atlanto-occipital dissociation presenting as locked-in syndrome
We present an unusual presentation of unstable atlanto-occipital dissociation as locked-in syndrome. Traumatic atlanto-occipital dissociation is a severe injury that accounts for 15–20% of all fatal cervical spinal injuries. A disruption occurs between the tectorial ligaments connecting the occipital condyle to the superior articulating facets of the atlas, resulting in anterior, longitudinal, or posterior translation, and it may be associated with Type III odontoid fractures. Furthermore, the dissociation may be complete (atlanto-occipital dislocation) or incomplete (atlanto-occipital subluxation), with neurologic findi...
Source: Journal of Clinical Neuroscience - July 17, 2015 Category: Neuroscience Source Type: research

Platelet activation markers overexpressed specifically in patients with aspirin-exacerbated respiratory disease
Aspirin-exacerbated respiratory disease (AERD) is characterized by respiratory reactions on ingestion of COX-1 inhibitors and cysteinyl leukotriene overproduction. The hypersensitivity reaction is induced by low doses of aspirin that inhibit COX-1 in platelets. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - July 17, 2015 Category: Allergy & Immunology Authors: Chihiro Mitsui, Keiichi Kajiwara, Hiroaki Hayashi, Jun Ito, Haruhisa Mita, Emiko Ono, Noritaka Higashi, Yuma Fukutomi, Kiyoshi Sekiya, Takahiro Tsuburai, Kazuo Akiyama, Kazuhiko Yamamoto, Masami Taniguchi Source Type: research

Comparison of different anesthesia techniques during esophagogastroduedenoscopy in children: a randomized trial
ConclusionRespiratory complications were more common in Group NA. The use of native airway with propofol maintenance during EGD does not offer advantages with respect to respiratory complications or institutional efficiency. (Source: Pediatric Anesthesia)
Source: Pediatric Anesthesia - July 17, 2015 Category: Anesthesiology Authors: Mario Patino, Susan Glynn, Mark Soberano, Philip Putnam, Md Monir Hossain, Clifford Hoffmann, Paul Samuels, Michael J. Kibelbek, Joel Gunter Tags: Original Article Source Type: research

Republished: The clinical spectrum of pulmonary aspergillosis
The clinical presentation of Aspergillus lung disease is determined by the interaction between fungus and host. Invasive aspergillosis develops in severely immunocompromised patients, including those with neutropenia, and increasingly in the non-neutropenic host, including lung transplant recipients, the critically ill patients and patients on steroids. A high index of suspicion is required in patients without the classical risk factors as early presentation is usually silent and non-specific, pyrexia uncommon and timely treatment is crucial for survival. Invasive aspergillosis has also been diagnosed in normal hosts after...
Source: Postgraduate Medical Journal - July 17, 2015 Category: Journals (General) Authors: Kosmidis, C., Denning, D. W. Tags: Reviews Source Type: research

'Photographic negative of pulmonary oedema': a classical radiographic pattern of chronic eosinophilic pneumonia
Introduction Chronic eosinophilic pneumonia (CEP) is a rare disease accounting for 0%–2.5% of cases in different registries of interstitial lung diseases.1 Photographic negative of pulmonary oedema or reverse bat wing appearance is pathognomic of CEP, but seen in less than one-third of the patients. CEP is a rare disorder of unknown cause associated with subacute or chronic respiratory symptoms, characterised by the abnormal accumulation of eosinophils in the lungs.2 It occurs predominantly in women and non-smokers, with peak incidence in the fifth decade with a mean age of 45 years. Approximately half of these ...
Source: Postgraduate Medical Journal - July 17, 2015 Category: Journals (General) Authors: Cherian, S. V., Thampy, E. Tags: Immunology (including allergy), Radiology, Asthma, Pneumonia (respiratory medicine), Surgical diagnostic tests, Cardiothoracic surgery, General surgery, Radiology (diagnostics) Images in medicine Source Type: research

Association between basal metabolic function and bone metabolism in postmenopausal women with type 2 diabetes
This study examined resting energy expenditure (REE) and respiratory quotient (RQ) as indices of bone metabolism in postmenopausal Japanese women with T2D. (Source: Nutrition)
Source: Nutrition - July 17, 2015 Category: Nutrition Authors: Makiko Ogata, Risa Ide, Miho Takizawa, Mizuho Tanaka, Tamaki Tetsuo, Asako Sato, Naoko Iwasaki, Yasuko Uchigata Source Type: research

Electronic Fetal Monitoring Patterns Associated with Respiratory Morbidity in Term Neonates
To identify electronic fetal monitoring patterns associated with neonatal respiratory morbidity. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 17, 2015 Category: OBGYN Authors: Lucy Liu, Methodius G. Tuuli, Kimberly A. Roehl, Anthony O. Odibo, George A. Macones, Alison G. Cahill Source Type: research

Low vs. high flow oxygen delivery systems in children with lower respiratory infection
ConclusionIn both groups, there was marked improvement in all measured parameters following introduction of supplemental oxygen. However, oxygen is delivered more efficiently by high‐flow systems. The Venturi mask may decrease the total duration of oxygen usage time as well as the length of hospitalization among young children with HALRI through rapid symptom resolution. This article is protected by copyright. All rights reserved. (Source: Pediatrics International)
Source: Pediatrics International - July 17, 2015 Category: Pediatrics Authors: Pinar Uygur, Sedat Oktem, Perran Boran, Engin Tutar, Gulnur Tokuc Tags: Original Article Source Type: research

Airflow limitation in COPD is associated with increased left ventricular wall stress in coincident heart failure
COPD and heart failure occur with a considerable coincidence. Beside well-known mechanisms of increased right heart load in COPD, dedicated changes of the left ventricle (LV) are ill-defined and the question remains, whether specific interactions exist beyond common shared risk factors. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - July 17, 2015 Category: Respiratory Medicine Authors: Peter Alter, Kirsten van de Sand, Christoph Nell, Jens H. Figiel, Timm Greulich, Claus F. Vogelmeier, Andreas R. Koczulla Source Type: research

Risk Factors for Postoperative Pneumonia after Lung Cancer Surgery and Impact of Pneumonia on Survival
Little is known about risk factors and prognosis for postoperative pneumonia (POP) in patients undergoing therapeutic lung cancer (LC) surgery. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - July 17, 2015 Category: Respiratory Medicine Authors: Dennis F. Simonsen, Mette Søgaard, Imre Bozi, Charles R. Horsburgh, Reimar W. Thomsen Source Type: research

Effect of weight reduction on obese patients with COPD and bronchial asthma
Conclusion Weight reduction improved airway obstruction, increased ERV, RV, FRC and DLCO either significant or insignificant in asthma and COPD. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - July 17, 2015 Category: Respiratory Medicine Source Type: research

Nanocomplexes for Gene Therapy of Respiratory Diseases: Targeting and Overcoming the MucusBarrier
Publication date: Available online 17 July 2015 Source:Pulmonary Pharmacology & Therapeutics Author(s): Sante Di Gioia, Adriana Trapani, Stefano Castellani, Annalucia Carbone, Giuliana Belgiovine, Emanuela Fabiola Craparo, Giovanni Puglisi, Gennara Cavallaro, Giuseppe Trapani, Massimo Conese Gene therapy, i.e. the delivery and expression of therapeutic genes, holds great promise for congenital and acquired respiratory diseases. Non-viral vectors are less toxic and immunogenic than viral vectors, although they are characterized by lower efficiency. However, they have to overcome many barriers, including ...
Source: Pulmonary Pharmacology and Therapeutics - July 17, 2015 Category: Respiratory Medicine Source Type: research

Urinary uric acid excretion as an indicator of severe hypoxia and mortality in patients with obstructive sleep apnea and chronic obstructive pulmonary disease
Conclusion UA excretion, as a marker of tissue hypoxia, may be useful in the management of OSA and COPD patients. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - July 17, 2015 Category: Respiratory Medicine Source Type: research

Residential exposure to air toxics is linked to lower grade point averages among school children in El Paso, Texas, USA
Abstract Children in low-income neighborhoods tend to be disproportionately exposed to environmental toxicants. This is cause for concern because exposure to environmental toxicants negatively affects health, which can impair academic success. To date, it is unknown if associations between air toxics and academic performance found in previous school-level studies persist when studying individual children. In pairing the National Air Toxics Assessment risk estimates for respiratory and diesel particulate matter risk disaggregated by source, with individual-level data collected through a mail survey, this paper exam...
Source: Population and Environment - July 17, 2015 Category: Environmental Health Source Type: research

Lost after translation: Insights From Surfactant For Understanding The Role Of Alveolar Epithelial Dysfunction And Cell Quality Control In Fibrotic Lung Disease.
Abstract Dating back nearly 35 years ago to the Witschi hypothesis, epithelial cell dysfunction and abnormal wound healing have reemerged as central concepts in the pathophysiology of idiopathic pulmonary fibrosis (IPF) in adults and in interstitial lung disease in children (chILD). Alveolar type 2 (AT2) cells represent a metabolically active compartment in the distal airspaces responsible for pulmonary surfactant biosynthesis and function as a progenitor population required for maintenance of alveolar integrity. Rare mutations in surfactant system components have provided new clues to understanding broader questio...
Source: Am J Physiol Lung Ce... - July 17, 2015 Category: Respiratory Medicine Authors: Mulugeta S, Nureki SI, Beers MF Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

HO-1/CO regulation of mitochondrial-capillary density relationships in human skeletal muscle.
Abstract The heme oxygenase-1/carbon monoxide (HO-1/CO) system induces mitochondrial biogenesis, but its biological impact in human skeletal muscle is uncertain. The enzyme generates carbon monoxide (CO), which stimulates mitochondrial proliferation in normal muscle. Here we examined whether CO breathing can be used to produce a coordinated metabolic and vascular response in human skeletal muscle. In nineteen healthy subjects, we performed vastus lateralis (VL) muscle biopsies and tested one-legged VO2max before and after breathing air or CO (200 ppm) for one hour daily for five days. In response to CO, there was r...
Source: Am J Physiol Lung Ce... - July 17, 2015 Category: Respiratory Medicine Authors: Pecorella SR, Potter JV, Cherry AD, Peacher DF, Welty-Wolf KE, Moon RE, Piantadosi CA, Suliman HB Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Reduced FoxO3a expression causes low autophagy in Idiopathic Pulmonary Fibrosis fibroblasts on collagen matrix.
Abstract Idiopathic Pulmonary Fibrosis (IPF) is a chronic and fatal lung disease, and fibroblasts derived from patients with IPF are resistant to type I collagen matrix-induced cell death. The alteration of the PTEN/Akt axis permits IPF fibroblasts to maintain a pathological phenotype on collagen by suppressing autophagy. However, the precise underlying mechanism by which the Akt down-stream molecule suppresses autophagic activity remains elusive. FoxO3a is a direct target of Akt and is implicated with the transcriptional activation of autophagy. Therefore, we investigated whether reduced FoxO3a expression causes a...
Source: Am J Physiol Lung Ce... - July 17, 2015 Category: Respiratory Medicine Authors: Im J, Hergert P, Nho RS Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

A review of recent developments and applications of morphometry/stereology in lung research.
Abstract Design-based stereology is the gold standard of morphometry in lung research. Here, we analyze the current use of morphometric and stereological methods in lung research and provide an overview on recent methodological developments and biological observations made by the use of stereology. Based on this analysis we hope to provide useful recommendations for a good stereological practice in order to further the use of advanced and unbiased stereological methods. PMID: 26186944 [PubMed - as supplied by publisher] (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - July 17, 2015 Category: Respiratory Medicine Authors: Mühlfeld C, Hegermann J, Wrede C, Ochs M Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Quantitative Magnetic Resonance Imaging of Bronchopulmonary Dysplasia in the NICU Environment.
CONCLUSIONS: Pulmonary MRI reveals quantifiable, significant differences between BPD patients, premature patients without BPD, and full-term controls; these methods could be implemented to individually phenotype disease, which may impact clinical care and predict future outcomes. PMID: 26186608 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - July 17, 2015 Category: Respiratory Medicine Authors: Walkup LL, Tkach JA, Higano NS, Thomen RP, Fain SB, Merhar SL, Fleck RJ, Amin RS, Woods JC Tags: Am J Respir Crit Care Med Source Type: research

Spatio-temporal Aeration and Lung Injury Patterns are Influenced by the First Inflation Strategy at Birth.
CONCLUSIONS: Mechanical and molecular consequences of lung aeration at birth are not simply related to rapidity of fluid clearance but the spatio-temporal pressure-volume interactions within the lung during inflation and deflation. PMID: 26186685 [PubMed - as supplied by publisher] (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - July 17, 2015 Category: Respiratory Medicine Authors: Tingay DG, Rajapaksa A, Zonneveld CE, Black D, Perkins EJ, Adler A, Grychtol B, Lavizzari A, Frerichs I, Zahra VA, Davis PG Tags: Am J Respir Cell Mol Biol Source Type: research

Sleep, Death and the Heart.
Abstract Obstructive and central sleep apnea have been associated with increased risk of adverse cardiovascular events and mortality. Sympathetic dysregulation occurring as a result of the respiratory disturbance is thought to play a role in this increased risk. Sleep apnea increases the risk of arrhythmias, myocardial ischemia/infarction, stroke, and heart failure, all of which may increase mortality risk. A higher incidence of nocturnal arrhythmias, cardiac ischemia and sudden death has been noted in subjects with sleep disordered breathing (SDB). In this review, the association between SDB and each of these cond...
Source: American Journal of Physiology. Heart and Circulatory Physiology - July 17, 2015 Category: Physiology Authors: Mansukhani MP, Wang S, Somers VK Tags: Am J Physiol Heart Circ Physiol Source Type: research

Development and performance assessment of a qualitative SYBR® green real-time PCR assay for the detection of Aspergillus versicolor in indoor air.
Abstract Currently, contamination of indoor environment by fungi and molds is considered as a public health problem. The monitoring of indoor airborne fungal contamination is a common tool to help understanding the link between fungi in houses and respiratory problems. Classical analytical monitoring methods, based on cultivation and microscopic identification, depend on the growth of the fungi. Consequently, they are biased by difficulties to grow some species on certain culture media and under certain conditions or by noncultivable or dead fungi that can consequently not be identified. However, they could have an...
Source: Applied Microbiology and Biotechnology - July 17, 2015 Category: Microbiology Authors: Libert X, Chasseur C, Bladt S, Packeu A, Bureau F, Roosens NH, De Keersmaecker SC Tags: Appl Microbiol Biotechnol Source Type: research

Inhaled Epoprostenol Is Noninferior to Inhaled Nitric Oxide for the Treatment of ARDS.
CONCLUSIONS: Inhaled epoprostenol was noninferior to inhaled nitric oxide with regard to ventilator-free days from day 1 to day 28 in ARDS patients. PMID: 26187741 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - July 17, 2015 Category: Drugs & Pharmacology Authors: Ammar MA, Bauer SR, Bass SN, Sasidhar M, Mullin R, Lam SW Tags: Ann Pharmacother Source Type: research

Multistage self-gated lung imaging in small rodents.
CONCLUSION: The presented respiratory gating method allows the reconstruction of different respiratory positions. Improved sharpness in expiration images was observed compared with ungated images. SNR and NSI changes in parenchyma reflect the expected variation of lung tissue density during respiration. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc. PMID: 26189455 [PubMed - as supplied by publisher] (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - July 17, 2015 Category: Radiology Authors: Tibiletti M, Kjørstad Å, Bianchi A, Schad LR, Stiller D, Rasche V Tags: Magn Reson Med Source Type: research

An ST11 clone of Pasteurella multocida, widely spread among farmed rabbits in the Iberian Peninsula, demonstrates respiratory niche association.
In this study, 100 P. multocida isolates from different commercial rabbit farms located throughout the Iberian Peninsula were molecularly characterized by capsular typing, detection of four virulence-associated genes (tbpA, toxA, hgbB, and pfhA), and multilocus sequence typing (MLST). Rabbit P. multocida isolates belonged to three different capsular types: A (47.0%), D (28.0%), and F (25.0%). One group of P. multocida isolates of capsular type D and positive for the hgbB gene was significantly associated with the clinical presentation of respiratory disease (OR 5.91; 95%CI, 1.63-21.38). These isolates belonged to same sequ...
Source: Infection, Genetics and Evolution - July 17, 2015 Category: Genetics & Stem Cells Authors: García-Alvarez A, Chaves F, Fernández A, Sanz C, Borobia M, Cid D Tags: Infect Genet Evol Source Type: research

Molecular genetic analysis of the Influenza A(H1N1)pdm09 virus from lethal and recovered cases in Russia from 2009 to 2014: Deletions in the nucleoprotein.
Abstract Influenza A(H1N1)pdm09 virus caused about 2000 laboratory confirmed lethal cases in Russia during 2009-2010 and 1302, 135 and 29 cases in the 2010-2011, 2012-2013 and 2013-2014 seasons respectively. The on average short duration (7.8±5days) of lethal cases of Influenza A(H1N1)pdm09 infections in Russia suggests primary viral rather than secondary bacterial pneumonia. Hemorrhagic syndrome was recorded in 36.6% of patients. An examination of 221 lung samples from lethal influenza cases for the presence of bacterial DNA that could cause pneumonia did not reveal bacterial superinfections in 86% of cases. Mole...
Source: Infection, Genetics and Evolution - July 17, 2015 Category: Genetics & Stem Cells Authors: Yatsyshina S, Renteeva A, Deviatkin A, Vorobyeva N, Minenko A, Valdokhina A, Elkina M, Kuleshov K, Shipulin G Tags: Infect Genet Evol Source Type: research

Animal models of Middle East respiratory syndrome coronavirus infection.
This article forms part of a symposium in Antiviral Research on "From SARS to MERS: research on highly pathogenic human coronaviruses." PMID: 26192750 [PubMed - as supplied by publisher] (Source: Antiviral Research)
Source: Antiviral Research - July 17, 2015 Category: Virology Authors: van Doremalen N, Munster VJ Tags: Antiviral Res Source Type: research

Inactivation and safety testing of Middle East Respiratory Syndrome Coronavirus.
Abstract Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a recently emerged virus that has caused a number of human infections and deaths, primarily in the Middle East. The transmission of MERS-CoV to humans has been proposed to be as a result of contact with camels, but evidence of human-to-human transmission also exists. In order to work with MERS-CoV in a laboratory setting, the US Centers for Disease Control and Prevention (CDC) has determined that MERS-CoV should be handled at a biosafety level (BSL) 3 (BSL-3) biocontainment level. Many processes and procedures used to characterize MERS-CoV and to e...
Source: Journal of Virological Methods - July 17, 2015 Category: Virology Authors: Kumar M, Mazur S, Ork BL, Postnikova E, Hensley LE, Jahrling PB, Johnson R, Holbrook MR Tags: J Virol Methods Source Type: research

Relation of lung function and current inhalant allergen-specific immunoglobulin E concentrations in adolescents (GINIplus cohort).
CONCLUSION: Although allergen-specific IgE concentrations can contribute to the identification of subjects at higher risk for allergic rhinitis and asthma, sensitization to inhalant allergens is not related to impaired spirometric lung parameters within the different allergic respiratory disease subgroups. PMID: 26195441 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - July 17, 2015 Category: Allergy & Immunology Authors: Luzak A, Flexeder C, von Berg A, Berdel D, Klümper C, Koletzko S, Bauer CP, Heinrich J, Nowak D, Schulz H Tags: Ann Allergy Asthma Immunol Source Type: research

Intrapulmonary Solitary Fibrous Tumors: Benign or Malignant?
PMID: 26195157 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - July 17, 2015 Category: Respiratory Medicine Authors: Schiavoni E, Alvarez Padilla F, Bustos M Tags: Arch Bronconeumol Source Type: research

Restrictive Fluid Resuscitation Leads to Better Oxygenation than Non-Restrictive Fluid Resuscitation in Piglets with Pulmonary or Extrapulmonary Acute Respiratory Distress Syndrome.
CONCLUSIONS RFR led to better oxygenation in ARDSp and ARDSexp compared with NRFR, but fluid restriction improved oxygenation in ARDSexp only. PMID: 26166324 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 16, 2015 Category: Research Tags: Med Sci Monit Source Type: research