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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

Efficacy of an attenuated European subtype 1 porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in pigs upon challenge with the East European subtype 3 PRRSV strain Lena.
In conclusion, it can be stated that vaccination of pigs with an attenuated European subtype 1 vaccine provides a partial protection against a subsequent exposure to the highly pathogenic East European subtype 3 PRRSV strain Lena. PMID: 24709589 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - April 4, 2014 Category: Allergy & Immunology Authors: Trus I, Bonckaert C, van der Meulen K, Nauwynck HJ Tags: Vaccine Source Type: research

Animal models for influenza virus pathogenesis, transmission, and immunology.
Abstract In humans, infection with an influenza A or B virus manifests typically as an acute and self-limited upper respiratory tract illness characterized by fever, cough, sore throat, and malaise. However, influenza can present along a broad spectrum of disease, ranging from sub-clinical or even asymptomatic infection to a severe primary viral pneumonia requiring advanced medical supportive care. Disease severity depends upon the virulence of the influenza virus strain and the immune competence and previous influenza exposures of the patient. Animal models are used in influenza research not only to elucidate the ...
Source: Journal of Immunological Methods - April 4, 2014 Category: Allergy & Immunology Authors: Thangavel RR, Bouvier NM Tags: J Immunol Methods Source Type: research

Differing Effects of Adaptive Servoventilation and Continuous Positive Airway Pressure on Muscle Sympathetic Nerve Activity in Patients With Heart Failure.
Conclusions: ASV probably exerts its sympathoinhibitory effects in patients with HF and PB through pressure support. PMID: 24705391 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - April 4, 2014 Category: Cardiology Authors: Ushijima R, Joho S, Akabane T, Oda Y, Inoue H Tags: Circ J Source Type: research

Effects of the Mitochondrial Respiratory Chain on Longevity in C. elegans.
Abstract How an organism ages is a question that has fascinated biologists, and the elderly, for centuries. One useful approach to understanding complex processes such as aging is to study genetic variation in model organisms such as the nematode, Caenorhabditis elegans. Classical mutant strains and RNAi screens have demonstrated that mitochondrial function is a major factor affecting longevity. Recent advances in the biochemical methods for studying mitochondrial functions have extended the usefulness of C. elegans for deciphering the molecular mechanisms by which mitochondria determine lifespan. Defects of all co...
Source: Experimental Gerontology - April 4, 2014 Category: Geriatrics Authors: Dancy BM, Sedensky MM, Morgan PG Tags: Exp Gerontol Source Type: research

Whole exome sequencing reveals topbp1 as a novel gene in idiopathic pulmonary arterial hypertension.
Conclusions: WES led to the discovery of TopBP1, a gene whose deficiency may increase susceptibly to small vessel loss in IPAH. We predict that use of WES will help identify gene modifiers that influence an individual's risk of developing IPAH. PMID: 24702692 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 4, 2014 Category: Respiratory Medicine Authors: de Jesus Perez VA, Yuan K, Lyuksyutova MA, Dewey F, Orcholski ME, Shuffle EM, Mathur M, Yancy L, Rojas V, Li CG, Cao A, Alastalo TP, Khazeni N, Cimprich KA, Butte AJ, Ashley E, Zamanian RT Tags: Am J Respir Crit Care Med Source Type: research

The upper respiratory tract as a microbial source for pulmonary infections in Cystic Fibrosis: Parallels from Island Biogeography.
Abstract A continuously mixed series of microbial communities inhabits various points of the respiratory tract, with community composition dictated by distance from colonization sources, colonization rates, and extinction rates. Ecology and evolution theory developed in the context of biogeography is relevant to clinical microbiology and could reframe the interpretation of recent studies comparing communities from lung explant samples, sputum samples and oropharyngeal swabs. We propose an Island Biogeography model of the microbial communities inhabiting different niches in human airways. Island biogeography as appl...
Source: American Journal of Respiratory and Critical Care Medicine - April 4, 2014 Category: Respiratory Medicine Authors: Whiteson KL, Bailey B, Bergkessel M, Conrad D, Delhaes L, Felts B, Harris JK, Hunter R, Lim YW, Maughan H, Quinn R, Salamon P, Sullivan J, Wagner BD, Rainey PB Tags: Am J Respir Crit Care Med Source Type: research

Serum levels of club cell secretory protein (Clara) and short- and long-term exposure to particulate air pollution in adolescents.
CONCLUSIONS: Our findings suggest that short-term exposure to particulate air pollution may compromise the integrity of the lung epithelium and lead to increased epithelial barrier permeability in the lungs of adolescents, even at low concentrations. PMID: 24709782 [PubMed - as supplied by publisher] (Source: Environment International)
Source: Environment International - April 4, 2014 Category: Environmental Health Authors: Provost EB, Chaumont A, Kicinski M, Cox B, Fierens F, Bernard A, Nawrot TS Tags: Environ Int Source Type: research

Time trends of polycyclic aromatic hydrocarbon exposure in New York city from 2001 to 2012: Assessed by repeat air and urine samples.
CONCLUSIONS: Multiple NYC legislative regulations targeting traffic-related air pollution may have led to decreases in ∑8PAHnonvolatile and BC, especially in the nonheating season. Despite the overall decrease in pyrene over the 2001-2012 periods, a rise in pyrene levels in recent years (2005-2012), that was particularly evident for measures collected during the heating season, and 2-naphthol, indicates the contribution of heating oil combustion and other indoor sources to airborne pyrene and urinary 2-naphthol. PMID: 24709094 [PubMed - as supplied by publisher] (Source: Environmental Research)
Source: Environmental Research - April 4, 2014 Category: Environmental Health Authors: Jung KH, Liu B, Lovinsky-Desir S, Yan B, Camann D, Sjodin A, Li Z, Perera F, Kinney P, Chillrud S, Miller RL Tags: Environ Res Source Type: research

Urban adolescents readily comply with a complicated asthma research protocol.
CONCLUSIONS: These findings suggest that early adolescents can be compliant with complex research protocols that are needed to help bridge gaps in pediatric asthma research. PMID: 24683308 [PubMed] (Source: Respiratory Care)
Source: Respiratory Care - April 3, 2014 Category: Respiratory Medicine Authors: Lovinsky-Desir S, Folch C, Jung KH, Torrone D, Gil E, Perera F, Miller RL, Chillrud SN Tags: Clin Med Insights Circ Respir Pulm Med Source Type: research

Acute bronchiolitis in infants, a review
Acute viral bronchiolitis is one of the most common medical emergency situations in infancy, and physicians caring for acutely ill children will regularly be faced with this condition. In this article we present a summary of the epidemiology, pathophysiology and diagnosis, and focus on guidelines for the treatment of bronchiolitis in infants. The cornerstones of the management of viral bronchiolitis are the administration of oxygen and appropriate fluid therapy, and overall a "minimal handling approach" is recommended. Inhaled adrenaline is commonly used in some countries, but the evidences are sparse. Recently, inhalation...
Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine - April 3, 2014 Category: Emergency Medicine Authors: Knut ØymarHåvard SkjervenIngvild Mikalsen Source Type: research

Increased prevalence and altered species composition of filamentous fungi in respiratory specimens from cystic fibrosis patients
Filamentous fungi cultured from respiratory tract specimens submitted to the department of clinical microbiology, Aarhus University Hospital, during 2010 were identified by morphology and by internal transcribed spacer (ITS) sequencing. Of 343 fungal isolates, discrepancies between identification methods were observed for four isolates (1.2%), while identification to species was achieved only with ITS sequencing for 16 isolates (4.7%). Filamentous fungi were isolated from 15% of cystic fibrosis (CF) respiratory samples in contrast to 2% of non‐CF samples. From CF patients, a total of nine different species were found in ...
Source: APMIS - April 3, 2014 Category: Research Authors: Signe M. Nielsen, Lise Kristensen, Annette Søndergaard, Kurt J. Handberg, Jørgen Stenderup, Niels Nørskov‐Lauritsen Tags: Original Article Source Type: research

Unilateral opaque or ‘white out’ hemithorax
(Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 3, 2014 Category: Respiratory Medicine Authors: Ugur Gonlugur, Makbule Gin, Tanseli Gonlugur, Arzu Mirici Tags: Letter to the Editor Source Type: research

Syndromes associated with mitochondrial DNA depletion
Mitochondrial dysfunction accounts for a large group of inherited metabolic disorders most of which are due to a dysfunctional mitochondrial respiratory chain (MRC) and, consequently, deficient energy production. MRC function depends on the coordinated expression of both nuclear (nDNA) and mitochondrial (mtDNA) genomes. Thus, mitochondrial diseases can be caused by genetic defects in either the mitochondrial or the nuclear genome, or in the cross-talk between the two. This impaired cross-talk gives rise to so-called nuclear-mitochondrial intergenomic communication disorders, which result in loss or instability of the mitoc...
Source: Italian Journal of Pediatrics - April 3, 2014 Category: Pediatrics Authors: Célia NogueiraLigia AlmeidaClaudia NestiIlaria PezziniArnaldo VideiraLaura VilarinhoFilippo Santorelli Source Type: research

Paraneoplastic Hu and CRMP5 antibodies are present in smokers without cancer or neurological disease
ConclusionsHu and CRMP5 antibodies were not associated with cancer or neurological disease in a large cohort of smokers and are therefore not always paraneoplastic. (Source: Respirology)
Source: Respirology - April 3, 2014 Category: Respiratory Medicine Authors: Tor H. Qvale, Anette Storstein, Kibret Mazengia, Tomas M.L. Eagan, Per S. Bakke, Christian A. Vedeler Tags: Original Article Source Type: research

Low‐flow oxygen: How much is your patient really getting?
(Source: Respirology)
Source: Respirology - April 3, 2014 Category: Respiratory Medicine Authors: Christine F. McDonald Tags: Editorial Source Type: research

Biomolecular markers in assessment and treatment of asthma
Abstract Asthma is a chronic and heterogeneous inflammatory disorder with several different phenotypes. Whereas clinical features of asthma are non‐specific and pulmonary function tests are often insensitive, further development is needed for efficient treatment or even early diagnosis. Recently, several airway inflammatory biomarkers have emerged as valuable tools in diagnosis and management of asthma. The analysis of molecular markers of airways inflammation has provided promising and non‐invasive techniques that facilitate the detection of disease phenotypes as well as measurement of therapeutic efficacy. Although c...
Source: Respirology - April 3, 2014 Category: Respiratory Medicine Authors: Farnaz Fatemi, Esmaeil Sadroddiny, Azam Gheibi, Taiebeh Mohammadi Farsani, Gholam Ali Kardar Tags: Review Source Type: research

Haemodynamic changes in pulmonary hypertension in patients with interstitial lung disease treated with PDE‐5 inhibitors
ConclusionsOur data suggest that treatment with PDE‐5 inhibitors improves pulmonary haemodynamic patients with PH secondary to ILD. (Source: Respirology)
Source: Respirology - April 3, 2014 Category: Respiratory Medicine Authors: Gregor S. Zimmermann, Werner Wulffen, Patrick Huppmann, Tobias Meis, Franziska Ihle, Jens Geiseler, Hanno H. Leuchte, Amanda Tufman, Juergen Behr, Claus Neurohr Tags: Original Article Source Type: research

Update in interventional pulmonology: A prologue to a new review series
(Source: Respirology)
Source: Respirology - April 3, 2014 Category: Respiratory Medicine Authors: Fabien Maldonado, Eric S. Edell, Patrick J. Barron, Rex C. Yung Tags: Series Editorial Source Type: research

Systemic steroids in COPD-the beauty and the beast
No abstract! (Source: Respiratory Research)
Source: Respiratory Research - April 3, 2014 Category: Respiratory Medicine Authors: Claus Vogelmeier Source Type: research

Evidence suggesting that oral corticosteroids increase mortality in stable chronic obstructive pulmonary disease
The use of oral corticosteroids, historically prescribed to improve lung function in patients with acute chronic obstructive pulmonary disease (COPD),  has been suggested to increase mortality in patients with stable COPD based on data from the National Emphysema Treatment Trial. (Source: Respiratory Research)
Source: Respiratory Research - April 3, 2014 Category: Respiratory Medicine Authors: Nobuyuki HoritaNaoki MiyazawaSatoshi MoritaRyota KojimaMiyo InoueYoshiaki IshigatsuboTakeshi Kaneko Source Type: research

Noncommunicable diseases among urban refugees and asylum-seekers in developing countries: a neglected health care need
With the increasing trend in refugee urbanisation, growing numbers of refugees are diagnosed with chronic noncommunicable diseases (NCDs). However, with few exceptions, the local and international communities prioritise communicable diseases. The aim of this study is to review the literature to determine the prevalence and distribution of chronic NCDs among urban refugees living in developing countries, to report refugee access to health care for NCDs and to compare the prevalence of NCDs among urban refugees with the prevalence in their home countries. Major search engines and refugee agency websites were systematically s...
Source: Globalization and Health - April 3, 2014 Category: Global & Universal Authors: Ahmed AmaraSyed Aljunid Source Type: research

Determining the Control Circuitry of Redox Metabolism at the Genome-Scale
by Stephen Federowicz, Donghyuk Kim, Ali Ebrahim, Joshua Lerman, Harish Nagarajan, Byung-kwan Cho, Karsten Zengler, Bernhard Palsson Determining how facultative anaerobic organisms sense and direct cellular responses to electron acceptor availability has been a subject of intense study. However, even in the model organism Escherichia coli, established mechanisms only explain a small fraction of the hundreds of genes that are regulated during electron acceptor shifts. Here we propose a qualitative model that accounts for the full breadth of regulated genes by detailing how two global transcription factors (TFs), ArcA and F...
Source: PLoS Genetics - April 3, 2014 Category: Genetics & Stem Cells Authors: Stephen Federowicz et al. Source Type: research

Exhaled carbon dioxide can be used to guide respiratory support in the delivery room
Conclusion: Observing tidal volume and ECO2 waveforms adds objectivity to clinical assessments. ECO2 could help assess lung aeration and improve lung recruitment immediately after birth This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - April 3, 2014 Category: Pediatrics Authors: Sylvia Os, Po‐Yin Cheung, Gerhard Pichler, Khalid Aziz, Megan O'Reilly, Georg M. Schmölzer Tags: Review Article Source Type: research

In this issue of Occupational Medicine
(Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Noone, P. Tags: In This Issue Source Type: research

Leaveism at work
(Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Hesketh, I., Cooper, C. L. Tags: Editorial Source Type: research

Otto Dix, The Match Seller 1920
(Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: McKiernan, M. Tags: Art and occupation Source Type: research

Magnetic fields and leukaemia risks in UK electricity supply workers
Conclusions This study found no convincing evidence to support the hypothesis that exposure to magnetic fields is a risk factor for leukaemia, and the findings are consistent with the hypotheses that both distant and recent magnetic field exposures are not causally related to the generality of leukaemia. The limited positive findings for ALL may well be chance findings. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Sorahan, T. Tags: Original Paper Source Type: research

Magnetic fields and brain tumour risks in UK electricity supply workers
Conclusions This study found no evidence to support the hypothesis that exposure to magnetic fields is a risk factor for gliomas, and the findings are consistent with the hypotheses that both distant and recent magnetic field exposures are not causally related to gliomas. The limited positive findings for meningioma may be chance findings; national comparisons argue against a causal interpretation. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Sorahan, T. Tags: Original Paper Source Type: research

Mental health and substance use among self-employed lawyers and pharmacists
Conclusions In our sample of these self-employed groups, both pharmacists and lawyers reported a high rate of psychological distress. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Leignel, S., Schuster, J.- P., Hoertel, N., Poulain, X., Limosin, F. Tags: Original Paper Source Type: research

Self-referrals to a doctors' mental health service over 10 years
Conclusions Increasing numbers of doctors sought help from the doctors’ mental health support service. More than half scored above the thresholds for burnout and psychological distress and these proportions were consistent over 10 years. Doctors may be more willing to seek help than a decade ago. Further research is needed to confirm the underlying reasons for this. More resource is needed to meet the increase in demand. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Meerten, M., Rost, F., Bland, J., Garelick, A. I. Tags: Original Paper Source Type: research

Worker expectations of occupational health consultations
Conclusions Worker expectations of OH physicians’ professional standards were lower than the standards set by national guidance as validated by the sampled OH physicians. Workers who felt more supported by their manager, and workers who were more apprehensive about the health impact of work had higher expectations of OH physicians’ standards. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Stilz, R., Madan, I. Tags: Original Paper Source Type: research

Longitudinal decline in pulmonary diffusing capacity among nitrate fertilizer workers
Conclusions This study indicates a larger than expected decline in the DLco of fertilizer workers during a 3-year follow-up. However, the decline was not related to specific exposures at work, or to possible covariates of exposure. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Hovland, K. H., Skogstad, M., Bakke, B., Skare, O., Skyberg, K. Tags: Original Paper Source Type: research

Sitting time and step counts in office workers
Conclusions Office workers who sit for a large proportion of their working day also report sitting for longer outside work. They do not compensate for their sedentary behaviour at work by being more active outside work. Occupational health interventions should focus on reducing workplace and leisure-time sitting in sedentary office workers. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Clemes, S. A., Patel, R., Mahon, C., Griffiths, P. L. Tags: Original Paper Source Type: research

Accuracy of body mass index in volunteer firefighters
Conclusions Although BMI ≥ 30 accurately predicted being over-fat, it misclassified large and lean firefighters. Although BMI should be used cautiously, it can identify over-fat firefighters at risk of cardiovascular disease, and its measurement is cost-effective and simple. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Ode, J., Knous, J., Schlaff, R., Hemenway, J., Peterson, J., Lowry, J. Tags: Original Paper Source Type: research

Development of the hearing protection assessment (HPA-2) questionnaire
Conclusions The HPA-2 questionnaire may be useful in both research and interventions to understand and motivate hearing protection behaviour by identifying and targeting supports and barriers to HPD use at different levels of the ecological model. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Reddy, R., Welch, D., Ameratunga, S., Thorne, P. Tags: Original Paper Source Type: research

Work-exacerbated asthma in a workers' compensation population
Conclusions The morbidity of WEA and the type of agents to which it was attributed varied between industry groups. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Lim, T., Liss, G. M., Vernich, L., Buyantseva, L., Tarlo, S. M. Tags: Original Paper Source Type: research

Prevalence of musculoskeletal symptoms in relation to psychosocial factors
Conclusions We found that WMSDs in the two populations presented different characteristics associated with their occupational features. This study provides further evidence that WMSDs occur commonly in both miners and school teachers in China. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Yue, P., Xu, G., Li, L., Wang, S. Tags: Original Paper Source Type: research

Tetanus immunity in construction workers in Italy
Conclusions In this study, a significant proportion of construction workers in Italy were not adequately immunized against tetanus, as required by Italian law. Occupational health professionals should promote and implement vaccination campaigns, especially among migrant workers, for public health and legal reasons. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Rapisarda, V., Bracci, M., Nunnari, G., Ferrante, M., Ledda, C. Tags: Original Paper Source Type: research

Retinal injury by industrial laser burn
We describe the mechanism of retinal injury, outcome and important issues regarding the safe use of lasers. (Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Scollo, P., Herath, G., Lobo, A. Tags: Case Report Source Type: research

Armadillo
(Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Hobson, J. Tags: Filler Source Type: research

Occupational medicine versus work medicine: etymological and semantic aspects
(Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Franco, G. Tags: Letter to the Editor Source Type: research

The GAD-7 questionnaire
(Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Williams, N. Tags: Questionnaire Review Source Type: research

Understanding and Using Health Experiences: Improving Patient Care
(Source: Occupational Medicine)
Source: Occupational Medicine - April 3, 2014 Category: Respiratory Medicine Authors: Basu, S. Tags: Book Review Source Type: research