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Respiratory Medicine

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

Animal Models of Chronic Obstructive Pulmonary Disease.
Abstract Animal models of disease have always been welcomed by the scientific community because they provide an approach to the investigation of certain aspects of the disease in question. Animal models of COPD cannot reproduce the heterogeneity of the disease and usually only manage to represent the disease in its milder stages. Moreover, airflow obstruction, the variable that determines patient diagnosis, not always taken into account in the models. For this reason, models have focused on the development of emphysema, easily detectable by lung morphometry, and have disregarded other components of the disease, suc...
Source: Archivos de Bronconeumologia - September 4, 2014 Category: Respiratory Medicine Authors: Pérez-Rial S, Girón-Martínez A, Peces-Barba G Tags: Arch Bronconeumol Source Type: research

Cannabinoid-induced changes in respiration of brain mitochondria.
Abstract Cannabinoids exert various biological effects that are either receptor-mediated or independent of receptor signaling. Mitochondrial effects of cannabinoids were interpreted either as non-receptor-mediated alteration of mitochondrial membranes, or as indirect consequences of activation of plasma membrane type 1 cannabinoid receptors (CB1). Recently, CB1 receptors were confirmed to be localized to the membranes of neuronal mitochondria, where their activation directly regulates respiration and energy production. Here, we performed in-depth analysis of cannabinoid-induced changes of mitochondrial respiration ...
Source: Toxicology Letters - September 4, 2014 Category: Toxicology Authors: Fišar Z, Singh N, Hroudová J Tags: Toxicol Lett Source Type: research

Excess Costs Associated With Complications and Prolonged Length of Stay After Congenital Heart Surgery.
CONCLUSIONS: Complications and prolonged LOS after congenital heart surgery are associated with significant costs. Initiatives able to achieve even modest reductions in these morbidities may lead to both improved outcomes and cost savings across both moderate and high complexity operations. PMID: 25201725 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - September 4, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Pasquali SK, He X, Jacobs ML, Shah SS, Peterson ED, Gaies MG, Hall M, Gaynor JW, Hill KD, Mayer JE, Li JS, Jacobs JP Tags: Ann Thorac Surg Source Type: research

Dexmedetomidine for infant pulmonary function testing
Summary For the last thirty years, oral chloral hydrate has been used for sedation of infants for lung function testing. Recently, however, availability of chloral hydrate became severely limited in the United States after two manufacturers discontinued manufacturing in 2012. Due to these limitations and the recent and ongoing shortage of chloral hydrate, other medications have been proposed for lung function testing, including midazolam and propofol. Herein, we describe our limited experience using intravenous dexmedetomedine (DMED), a medication thus far described as having minimal effect on pulmonary function or respira...
Source: Pediatric Pulmonology - September 3, 2014 Category: Respiratory Medicine Authors: Patrick Callahan, Swaroop J. Pinto, Geoffrey Kurland, James G. Cain, Etsuro K. Motoyama, Daniel J. Weiner Tags: Original Article: Diagnostic Testing Source Type: research

Daily pain in adolescents with CF: Effects on adherence, psychological symptoms, and health‐related quality of life
ConclusionsResults indicated that pain is a common problem for adolescents with CF and negatively affects their disease management, psychological symptoms and health outcomes. Routine assessment of pain and systematic studies of interventions to treat pain are recommended. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - September 3, 2014 Category: Respiratory Medicine Authors: Laura S. Blackwell, Alexandra L. Quittner Tags: Original Article: Cystic Fibrosis Source Type: research

Asthma control questionnaires in the management of asthma in children: A review
Summary Several self‐administered questionnaires have been developed to assess childhood asthma control in a simple and standardized way. This review discusses the most commonly used questionnaires and explores their usefulness in asthma management in children. We conclude that the use of asthma control questionnaires in daily practice and in research contributes to the standardized evaluation of children with asthma and helps to track asthma symptoms, but validation studies in a wider range of settings are needed. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - September 3, 2014 Category: Respiratory Medicine Authors: S. Voorend‐van Bergen, A.A. Vaessen‐Verberne, J.C. de Jongste, M.W. Pijnenburg Tags: Review Source Type: research

Impact of traffic related air pollution indicators on non-cystic fibrosis bronchiectasis mortality: a cohort analysis
Conclusion: Traffic-related air pollution appears to increase the risk of dying in patients with NCFB.Trial registrationThe study was approved by the local ethical committee of the UZ Leuven, Belgium (ML-5028), registered at ClinicalTrial.gov (NCT01906047). (Source: Respiratory Research)
Source: Respiratory Research - September 3, 2014 Category: Respiratory Medicine Authors: Pieter GoeminneEsmee BijnensBen NemeryTim NawrotLieven Dupont Source Type: research

Evaluation of acid–base disorders in dogs and cats presenting to an emergency room. Part 1: Comparison of three methods of acid–base analysis
Conclusions and Clinical RelevanceThe physicochemical approaches diagnosed more acid–base abnormalities in this population than the traditional approach although many of the abnormalities identified were small and of unknown clinical relevance. The physicochemical approaches may provide greater insight as to the underlying etiology of abnormalities, which maybe of particular relevance to cases with changes in albumin and/or phosphorus concentration. (Source: Journal of Veterinary Emergency and Critical Care)
Source: Journal of Veterinary Emergency and Critical Care - September 3, 2014 Category: Veterinary Research Authors: Kate Hopper, Steven E. Epstein, Philip H. Kass, Matthew S. Mellema Tags: Original Study Source Type: research

Coexistence of mixed phenotype Creutzfeldt‐Jakob disease, Lewy body disease and argyrophilic grain disease plus histological features of possible Alzheimer's disease: A multi‐protein disorder in an autopsy case
We report hereby an autopsy case of sporadic mixed phenotype CJD without hereditary burden and a long‐term clinical course. An 80‐year old man was diagnosed with mild cognitive impairment 27 months before death, caused by bronchopneumonia and severe respiratory impairment. During this time, the patient developed gradual mental deterioration, some sleeping problems and myoclonus. Other clinical manifestations were progressive gait problems, language deterioration, presence of primitive reflexes and irritability. In keeping with those symptoms, a rapidly evolving dementia was clinically suspected. Cerebrospinal fluid tes...
Source: Neuropathology - September 3, 2014 Category: Neurology Authors: Iván Fernández‐Vega, Javier Ruiz‐Ojeda, Ramon A. Juste, Maria Geijo, Juan Jose Zarranz, Jose Luis Sánchez Menoyo, Ikerne Vicente‐Etxenausia, Jennifer Mediavilla‐García, Isabel Guerra‐Merino Tags: CASE REPORT Source Type: research

The Role of Bacteria in the Pathogenesis and Progression of Idiopathic Pulmonary Fibrosis.
Conclusions: IPF is characterised by an increased bacterial burden in BAL that predicts decline in lung function and death. Trials of antimicrobial therapy are needed to determine if microbial burden is pathogenic in the disease. PMID: 25184687 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - September 3, 2014 Category: Respiratory Medicine Authors: Molyneaux PL, Cox MJ, Willis-Owen SA, Mallia P, Russell KE, Russell AM, Murphy E, Johnston SL, Schwartz DA, Wells AU, Cookson WO, Maher TM, Moffatt MF Tags: Am J Respir Crit Care Med Source Type: research

Early exposure to bio-contaminants and asthma up to 10 years of age: results of the HITEA study.
Abstract Inverse associations have been found between exposure to bio-contaminants and asthma and allergies. The aim of this study was to prospectively assess whether early exposure to bio-contaminants in dust is associated with asthma and allergy later in childhood among children from (sub)-urban areas. In subsets of three European birth cohorts (PIAMA: n = 553; INMA: n = 481; and LISAplus: n = 395), endotoxin, (1,3,)-β-d-glucan and extracellular polysaccharide were measured in dust from living rooms shortly after birth. Current asthma at 6 years and 10 years of age and ever asthma up to 10 years of age were asse...
Source: Respiratory Care - September 3, 2014 Category: Respiratory Medicine Authors: Tischer C, Casas L, Wouters IM, Doekes G, Garcia-Esteban R, Gehring U, Hyvärinen A, Oldenwening M, Kerkhof M, Sunyer J, Standl M, Thiering E, Torrent M, Heinrich J, the HITEA study group Tags: Eur Respir J Source Type: research

Effect of upper-airway stimulation for obstructive sleep apnoea on airway dimensions.
This study evaluated stimulation effects on retropalatal and retrolingual dimensions during drug-induced sedation compared with wakefulness to assess mechanistic relationships in response to UAS. Patients with an implanted stimulator underwent nasal video endoscopy while awake and/or during drug-induced sedation in the supine position. The cross-sectional area, anterior-posterior and lateral dimensions of the retropalatal and retrolingual regions were measured during baseline and stimulation. 15 patients underwent endoscopy while awake and 12 underwent drug-induced sedation endoscopy. Increased levels of stimulation were a...
Source: Respiratory Care - September 3, 2014 Category: Respiratory Medicine Authors: Safiruddin F, Vanderveken OM, de Vries N, Maurer JT, Lee K, Ni Q, Strohl KP Tags: Eur Respir J Source Type: research

The different clinical faces of obstructive sleep apnoea: a cluster analysis.
This study was the first to apply cluster analysis to identify subtypes of patients with OSA who experience distinct combinations of symptoms and comorbidities. An analysis of baseline data from the Icelandic Sleep Apnoea Cohort (822 patients with newly diagnosed moderate-to-severe OSA) was performed. Three distinct clusters were identified. They were classified as the "disturbed sleep group" (cluster 1), "minimally symptomatic group" (cluster 2) and "excessive daytime sleepiness group" (cluster 3), consisting of 32.7%, 24.7% and 42.6% of the entire cohort, respectively. The probabilities of having comorbid hypertension an...
Source: Respiratory Care - September 3, 2014 Category: Respiratory Medicine Authors: Ye L, Pien GW, Ratcliffe SJ, Björnsdottir E, Arnardottir ES, Pack AI, Benediktsdottir B, Gislason T Tags: Eur Respir J Source Type: research

A self-management programme for COPD: a randomised controlled trial.
Abstract Studies of programmes of self-management support for chronic obstructive pulmonary disease (COPD) have been inconclusive. The Self-Management Programme of Activity, Coping and Education (SPACE) FOR COPD is a 6-week self-management intervention for COPD, and this study aimed to evaluate the effectiveness of this intervention in primary care. A single-blind randomised controlled trial recruited people with COPD from primary care and randomised participants to receive usual care or SPACE FOR COPD. Outcome measures were performed at baseline, 6 weeks and 6 months. The primary outcome was symptom burden, measur...
Source: Respiratory Care - September 3, 2014 Category: Respiratory Medicine Authors: Mitchell KE, Johnson-Warrington V, Apps LD, Bankart J, Sewell L, Williams JE, Rees K, Jolly K, Steiner M, Morgan M, Singh SJ Tags: Eur Respir J Source Type: research

Institutional care for long-term mechanical ventilation in Canada: A national survey.
PMID: 25184510 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - September 3, 2014 Category: Respiratory Medicine Authors: Rose L, McKim D, Katz S, Leasa D, Nonoyama M, Pedersen C, Avendano M, Goldstein R Tags: Can Respir J Source Type: research

Biomarker discovery in asthma and copd by proteomic approaches
This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - September 3, 2014 Category: Biochemistry Authors: Rossana Rossi, Antonella De Palma, Louise Benazzi, Anna Maria Riccio, Giorgio Walter Canonica, Pierluigi Mauri Tags: Review Source Type: research

Sensory irritation as a basis for setting occupational exposure limits.
Abstract There is a need of guidance on how local irritancy data should be incorporated into risk assessment procedures, particularly with respect to the derivation of occupational exposure limits (OELs). Therefore, a board of experts from German committees in charge of the derivation of OELs discussed the major challenges of this particular end point for regulatory toxicology. As a result, this overview deals with the question of integrating results of local toxicity at the eyes and the upper respiratory tract (URT). Part 1 describes the morphology and physiology of the relevant target sites, i.e., the outer eye, ...
Source: Archives of Toxicology - September 3, 2014 Category: Toxicology Authors: Brüning T, Bartsch R, Bolt HM, Desel H, Drexler H, Gundert-Remy U, Hartwig A, Jäckh R, Leibold E, Pallapies D, Rettenmeier AW, Schlüter G, Stropp G, Sucker K, Triebig G, Westphal G, van Thriel C Tags: Arch Toxicol Source Type: research

Evaluation and validation of four translated Chinese questionnaires for obstructive sleep apnea patients in Hong Kong.
CONCLUSION: Among the four questionnaires studied, STOP-BANG, with only eight questions and the highest sensitivity, is the best questionnaire of the four for OSA screening. This can potentially assist in prioritizing PSG and can be helpful in clinical or self-evaluation by the general public. PMID: 25182345 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - September 3, 2014 Category: Sleep Medicine Authors: Ha SC, Lee DL, Abdullah VJ, van Hasselt CA Tags: Sleep Breath Source Type: research

Video-Assisted Minithoracotomy Diaphragmatic Plication: Respiratory Effects in Adults.
Conclusions VAM-T DP is a viable and safe procedure that improves the spirometry values and offers stable results during the first year. To our knowledge, the present series is the second largest published report in English relating to this procedure in adults. PMID: 25184611 [PubMed - as supplied by publisher] (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - September 3, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Rombolá C, Crespo MG, López PT, Martínez AH, Atance PL, Ramírez AT, Montes JA Tags: Thorac Cardiovasc Surg Source Type: research

Salvianolic Acid A Prevents the Pathological Progression of Hepatic Fibrosis in High-Fat Diet-Fed and Streptozotocin-Induced Diabetic Rats.
Abstract Type 2 diabetes patients have an increased risk of developing hepatic fibrosis. Salvianolic acid A (SalA) has been reported to be a strong polyphenolic anti-oxidant and free radical scavenger. The aim of the present study was to evaluate the effect of SalA on the pathological progression of hepatic fibrosis in high-fat diet (HFD)-fed and streptozotocin (STZ)-induced diabetic rats and to clarify the underlying mechanisms. Type 2 diabetic animal model with hepatic fibrosis was developed by a high-sucrose, HFD and low-dose STZ injection (i.p.). Diabetic rats were randomly divided into SalA group (0.3 mg/kg/da...
Source: The American Journal of Chinese Medicine - September 3, 2014 Category: Complementary Medicine Authors: Qiang G, Yang X, Xuan Q, Shi L, Zhang H, Chen B, Li X, Zu M, Zhou D, Guo J, Yang H, Zhang L, Du G Tags: Am J Chin Med Source Type: research

Dual effects of carnosine on energy metabolism of cultured cortical astrocytes under normal and ischemic conditions.
CONCLUSIONS: Carnosine may be an endogenous regulator of astrocyte energy metabolism and a clinically safe therapeutic agent for promoting brain energy metabolism recovery after ischemia/reperfusion injury. PMID: 25195162 [PubMed - as supplied by publisher] (Source: Regulatory Peptides)
Source: Regulatory Peptides - September 3, 2014 Category: Biochemistry Authors: Shen Y, Tian Y, Yang J, Shi X, Ouyang L, Gao J, Lu J Tags: Regul Pept Source Type: research

Reactivity of ligand-swapped mutants of the SCO protein from Bacillus subtilis. Isomers of the CCH metal binding motif.
Abstract The Synthesis of Cytochrome Oxidase protein, or SCO protein, is required for the assembly of cytochrome c oxidase in many mitochondrial and bacterial respiratory chains. SCOs have been proposed to deliver copper to the CuA site of cytochrome c oxidase. We have reported that Bacillus subtilis SCO (i.e., BsSCO) binds Cu(II) with high-affinity via a two-step process mediated by three conserved residues (i.e., two cysteines and one histidine, or the CCH motif). A remarkable feature in the reaction of reduced (i.e., di-thiol) BsSCO with copper is that it does not generate any of the disulfide form of BsSCO. Thi...
Source: Biochimica et Biophysica Acta - September 3, 2014 Category: Biochemistry Authors: Yao X, Andrews D, Hill BC Tags: Biochim Biophys Acta Source Type: research

Chylothorax and Chylous Ascites. Management and Pitfalls
Leakage of lymph from the lymphatic ducts causes Chylothorax (CT) or Chylous ascitis (CA). This may happen for unknown reasons during fetal life or after birth and may also be caused by trauma after thoracic surgery or by other conditions. Fetal CT and CA may be lethal particularly in cases with fetal hydrops that sometimes benefit of intrauterine instrumentation. After birth, symptoms are related to the amount of accumulated fluid. Sometimes, severe cardio-respiratory compromise prompts active therapy. (Source: Seminars in Pediatric Surgery)
Source: Seminars in Pediatric Surgery - September 3, 2014 Category: Pediatrics Authors: Juan C. Lopez-Gutierrez, Juan A. Tovar Tags: #10 Source Type: research

Group 2 Innate Lymphoid Cells in the Lung.
Abstract As the first line of defense, innate immunity plays an important role in protecting the host against pathogens. Innate lymphoid cells (ILCs) are emerging as important effector cells in the innate immune system and the cell type that regulate immune and tissue homeostases. Group 2 ILCs (ILC2s) are a subset of ILCs and are characterized by their capacity to produce large quantities of type 2 cytokines and certain tissue growth factors. In animal models, lung ILC2s are involved in allergic airway inflammation induced by exposure to allergens even in the absence of CD4(+) T cells and are likely responsible for...
Source: Advances in Immunology - September 2, 2014 Category: Allergy & Immunology Authors: Drake LY, Kita H Tags: Adv Immunol Source Type: research

Ineffective airway clearance: prevalence and spectrum of its clinical indicators
Conclusion: The nursing diagnosis showed a high prevalence and association between indicators and the likelihood of identifying the nursing diagnosis was established. (Source: Acta Paulista de Enfermagem)
Source: Acta Paulista de Enfermagem - September 2, 2014 Category: Nursing Source Type: research

Alterations in the physiological parameters of newborns using oxygen therapy in the collection of blood gases
Conclusion: The painful stimulus caused by the collection of blood gases in newborns showed changes in all physiological parameters, however, for such a procedure, the changes were different for each mode of oxygen therapy. (Source: Acta Paulista de Enfermagem)
Source: Acta Paulista de Enfermagem - September 2, 2014 Category: Nursing Source Type: research

Hemodynamic Effect of Laser Therapy in Spontaneously Hypertensive Rats
The objective of this study was to analyze the action of low-level laser in the hemodynamic modulation of spontaneously hypertensive rats, in the long term. Animals (n = 16) were randomly divided into the Laser Group (n = 8), which received three weekly LLLT irradiations for seven weeks, and into the Sham Group (n = 8), which received three weekly simulations of laser for seven weeks, accounting for 21 applications in each group. After seven weeks, animals were cannulated by the implantation of a catheter in the left carotid artery. On the following day, the systemic arterial pressure was recorded. The Laser Group showed r...
Source: Arquivos Brasileiros de Cardiologia - September 2, 2014 Category: Cardiology Source Type: research

Investigating the relationship between peak inspiratory flow rate and volume of inhalation from a DiskusTM Inhaler and baseline spirometric parameters: a cross-sectional study
Drug delivery from a DPI is dependent on the peak inspiratory flow rate (PIFR) generated. Currently available methods for estimating PIFR from most DPIs are limited and mainly rely on subjective assessment. To show that spirometric and DiskusTM PIFR and Inspiratory Vital Capacity (IVC) are related to the underlying respiratory condition. To show that there is a linear relationship between spirometric PIFR and DiskusTM PIFR.Healthy volunteers and patients with asthma, COPD, neuromuscular disease and non-respiratory disorders were recruited (n = 85). Demographics and baseline lung function by spirometry were recorded. Flow a...
Source: BioMed Central - September 2, 2014 Category: Journals (General) Authors: Jansen N SeheultSimon CostelloKee Chun TeeTariq BholahHasan Al BannaiImran SulaimanRichard W Costello Source Type: research

Hospitalizations for Severe Lower Respiratory Tract Infections
Lower respiratory tract infections (LRTIs), including pneumonia, are in the top 10 causes of death among children in the United States. In high-income countries, 3% to 14% of LRTI hospitalizations have been reported to require admission to an ICU. During 2007–2011, approximately 31 289 hospitalizations for severe LRTI occurred in children each year in the United States. Children <1 year of age had the highest rates of severe LRTI and accounted for 30% of severe LRTI hospitalizations. (Read the full article) (Source: PEDIATRICS)
Source: PEDIATRICS - September 2, 2014 Category: Pediatrics Tags: Pediatrics Digest Summary Source Type: research

Severe Complications in Influenza-like Illnesses
Severe complications, such as respiratory failure, have been described in influenza infection. Clinicians are commonly faced with influenza-like illnesses (ILI), which is the initial nonspecific presentation of many respiratory viruses; the risk of severe complications from ILI are unknown. Severe complications occurred in children initially presenting with ILI, irrespective of the virus identified. Risk factors for severe complications did not differ by demographics or respiratory virus, although children with high-risk conditions are at greater risk of severe complications. (Read the full article) (Source: PEDIATRICS)
Source: PEDIATRICS - September 2, 2014 Category: Pediatrics Tags: Pediatrics Digest Summary Source Type: research

Hospitalizations for Severe Lower Respiratory Tract Infections
CONCLUSIONS: Among children, the burden of hospitalization for severe LRTI is greatest among children aged <1 year. Children with underlying medical conditions are at greatest risk for severe LRTI hospitalization. (Source: PEDIATRICS)
Source: PEDIATRICS - September 2, 2014 Category: Pediatrics Authors: Greenbaum, A. H., Chen, J., Reed, C., Beavers, S., Callahan, D., Christensen, D., Finelli, L., Fry, A. M. Tags: Article Source Type: research

Severe Complications in Influenza-like Illnesses
CONCLUSION: In children presenting to the ED for moderate to severe ILI, those with neurologic and neuromuscular disease are at increased risk for severe complications. Development of severe complications did not differ by infecting virus; however, risk of severe complications was greater with subtype H1N1 compared with other influenza. (Source: PEDIATRICS)
Source: PEDIATRICS - September 2, 2014 Category: Pediatrics Authors: Mistry, R. D., Fischer, J. B., Prasad, P. A., Coffin, S. E., Alpern, E. R. Tags: Article Source Type: research

Autosomal Recessive Polycystic Kidney Disease: A Hepatorenal Fibrocystic Disorder With Pleiotropic Effects
Autosomal recessive polycystic kidney disease (ARPKD) is an important cause of chronic kidney disease in children. The care of ARPKD patients has traditionally been the realm of pediatric nephrologists; however, the disease has multisystem effects, and a comprehensive care strategy often requires a multidisciplinary team. Most notably, ARPKD patients have congenital hepatic fibrosis, which can lead to portal hypertension, requiring close follow-up by pediatric gastroenterologists. In severely affected infants, the diagnosis is often first suspected by obstetricians detecting enlarged, echogenic kidneys and oligohydramnios ...
Source: PEDIATRICS - September 2, 2014 Category: Pediatrics Authors: Hartung, E. A., Guay-Woodford, L. M. Tags: State-of-the-Art Review Article Source Type: research

Tachypnea of Infancy as the First Sign of Sanfilippo Syndrome
This report describes the first known case of Mucopolysaccharidosis type IIIA presenting with respiratory symptoms and characteristic lung pathology. This case highlights under-recognized areas of systemic involvement and earlier modes of presentation in lysosomal storage disorders as well as the importance of investigating infants who have persistent tachypnea. (Source: PEDIATRICS)
Source: PEDIATRICS - September 2, 2014 Category: Pediatrics Authors: Chiang, J., Raiman, J., Cutz, E., Solomon, M., Dell, S. Tags: Case Report Source Type: research

Serum thyroid-stimulating hormone levels are not associated with exercise capacity and lung function parameters in two population-based studies
Conclusions: Our results suggest that thyroid dysfunction is not associated with lung function and cardiopulmonary exercise capacity in the general population. (Source: BMC Pulmonary Medicine - Latest articles)
Source: BMC Pulmonary Medicine - Latest articles - September 2, 2014 Category: Respiratory Medicine Authors: Till IttermannSven GläserRalf EwertStephan FelixHenry VölzkeMarcus Dörr Source Type: research

Respiratory virus is a real pathogen in immunocompetent community-acquired pneumonia: comparing to influenza like illness and volunteer controls
Conclusion: Respiratory virus was not a bystander, but pathogenic in pneumonia and was a common cause of CAP. (Source: BMC Pulmonary Medicine - Latest articles)
Source: BMC Pulmonary Medicine - Latest articles - September 2, 2014 Category: Respiratory Medicine Authors: Yangqing ZhanZifeng YangRongchang ChenYutao WangWenda GuanSuishan Zhao Source Type: research

A cross-sectional study of the association between ventilation of gas stoves and chronic respiratory illness in U.S. children enrolled in NHANESIII
Conclusions: In homes that used gas stoves, children whose parents reported using ventilation when operating their stove had higher lung function and lower odds of asthma, wheeze, and bronchitis compared to homes that never used ventilation or did not have ventilation available after adjusting for other risk factors. Additional research on the efficacy of ventilation as an intervention for ameliorating respiratory symptoms in children with asthma is warranted. (Source: Environmental Health)
Source: Environmental Health - September 2, 2014 Category: Environmental Health Authors: Molly KileEric CokerEllen SmitDaniel SudakinJohn MolitorAnna Harding Source Type: research

S. oneidensis nanowires are membrane extensions [Microbiology]
Bacterial nanowires offer an extracellular electron transport (EET) pathway for linking the respiratory chain of bacteria to external surfaces, including oxidized metals in the environment and engineered electrodes in renewable energy devices. Despite the global, environmental, and technological consequences of this biotic–abiotic interaction, the composition, physiological relevance, and electron transport... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - September 2, 2014 Category: Science Authors: Pirbadian, S., Barchinger, S. E., Leung, K. M., Byun, H. S., Jangir, Y., Bouhenni, R. A., Reed, S. B., Romine, M. F., Saffarini, D. A., Shi, L., Gorby, Y. A., Golbeck, J. H., El-Naggar, M. Y. Tags: Biological Sciences Source Type: research

[Oxygen uptake during "Nordic Walking" training in patients rehabilitated after coronary events.]
CONCLUSIONS: The intensity of Nordic Walking training in the field condition in patients after coronary events was 59 % VO₂R, and its temporary peak value reached obtained in CPET on treadmill. Energy expended during the NW in the study group was 8.1 Kcal/min. Chronotropic response in NW stood at 64% HRR, and its temporary increase reached the maximum frequency obtained during CPET. PMID: 25179476 [PubMed - as supplied by publisher] (Source: Polish Heart Journal)
Source: Polish Heart Journal - September 2, 2014 Category: Cardiology Authors: Rybicki JR, Leszczyńska-Bolewska BM, Grochulska WE, Malina TF, Jaros AJ, Samek KD, Baner AA, Kapko WS Tags: Kardiol Pol Source Type: research

Metabolic load during strength training or NMES in individuals with COPD: results from the DICES trial
Conclusions: To conclude, the metabolic load and symptom scores remain acceptable low over time with increasing training loads during HF-NMES, LF-NMES or strength training.Trial registration: Trial registration: NTR2322 (Source: BMC Pulmonary Medicine - Latest articles)
Source: BMC Pulmonary Medicine - Latest articles - September 2, 2014 Category: Respiratory Medicine Authors: Maurice SillenFrits FranssenAnouk VaesJeannet DelbressineEmiel WoutersMartijn Spruit Source Type: research

Diesel exhaust modulates ozone-induced lung function decrements in healthy human volunteers
The potential effects of combinations of dilute whole diesel exhaust (DE) and ozone (O3), each a common component of ambient airborne pollutant mixtures, on lung function were examined. Healthy young human volunteers were exposed for 2?hr to pollutants while exercising (~50?L/min) intermittently on two consecutive days. Day 1 exposures were either to filtered air, DE (300 ?g/m3), O3 (0.300?ppm), or the combination of both pollutants. On Day 2 all exposures were to O3 (0.300?ppm), and Day 3 served as a followup observation day. Lung function was assessed by spirometry just prior to, immediately after, and up to 4?hr post-ex...
Source: Particle and Fibre Toxicology - September 2, 2014 Category: Toxicology Authors: Michael MaddenTina StevensMartin CaseMichael SchmittDavid Diaz-SanchezMaryann BassettTracey MontillaJon BerntsenRobert Devlin Source Type: research