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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

Confluence-dependent resistance to cisplatin in lung cancer cells is regulated by transforming growth factor-beta.
CONCLUSIONS: CDR to cisplatin can occur in NSCLC cells, and the TGF-β pathway is associated with the regulation of CDR. PMID: 27116015 [PubMed - as supplied by publisher] (Source: Experimental Lung Research)
Source: Experimental Lung Research - April 27, 2016 Category: Respiratory Medicine Tags: Exp Lung Res Source Type: research

Cost of severe asthma in Brazil - Systematic review.
Conclusion Hospitalizations and medications seem to be the most important resources funded by the Brazilian public health system and by patients and their families. Although further studies are necessary, as information on cost of this disease is scarce in Brazil, these findings suggest that there is a potential room for improving severe asthma care among Brazilian patients. PMID: 27116649 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - April 27, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Adolescent, caregiver, and friend preferences for integrating social support and communication features into an asthma self-management app.
CONCLUSIONS: Given preferences expressed in this study, apps may help adolescents obtain social support to better self-manage their asthma. Future app-based interventions should include features enabling adolescents with asthma to communicate and interact with their caregivers, medical providers, and friends. PMID: 27116540 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - April 27, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Pediatric acute asthma exacerbations: evaluation and management from emergency department to intensive care unit.
CONCLUSIONS: Asthma is the most common chronic disease of childhood, and acute exacerbations are a significant burden to patients and to public health. Optimal assessment and management of exacerbations, including appropriate escalation of interventions, are essential to minimize morbidity and prevent mortality. While inhaled albuterol and systemic corticosteroids are the mainstay of exacerbation management, escalation may include interventions discussed in this review. PMID: 27116362 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - April 27, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Asthma-specific health related quality of life of people in Great Britain: A national survey.
CONCLUSIONS: This paper provides benchmarking data on asthma-specific HRQOL. Improved strategies are needed to target interventions towards people experiencing poor HRQOL. PMID: 27115826 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - April 27, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Outcomes of Follow-Up Care After an Emergency Department Visit Among Pediatric Asthmatics in the Military Health System.
CONCLUSIONS: Despite universal access to healthcare, less than half of pediatric MHS asthma patients had follow-up within 28 days of an ED visit. Those with follow-up were more likely to fill a controller medication within 90 days post ED visit, and less likely to have an asthma ED re-visit in the subsequent year. PMID: 27115719 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - April 27, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Acculturation and Quality of Life in Urban, African American Caregivers of Children with Asthma.
CONCLUSIONS: Less acculturation tied to religious beliefs/practices and family values (as measured by the AAAS-R) may serve a protective role in reducing the burden low-income, urban African American caregivers experience in managing child asthma. This study is the first of its kind to study acculturation in African American caregivers of children with asthma. PMID: 27115558 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - April 27, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

CT-assessed large airway involvement and lung function decline in eosinophilic asthma: The association between induced sputum eosinophil differential counts and airway remodeling.
CONCLUSIONS: The findings indicate that induced sputum eosinophil differential counts may be associated with airway remodeling in patients with stable asthma. PMID: 27115448 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - April 27, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Asthma, COPD and comorbidities in elderly people.
CONCLUSION: Asthma coexisted frequently with arterial hypertension and depression in elderly patients. Patients with COPD have a more exaggerated profile of coexisting diseases, specifically cardiovascular problems. PMID: 27115313 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - April 27, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Development of a patient decision aid on inhaled corticosteroids use for adults with asthma.
CONCLUSION: Our newly developed PDA was found acceptable and usable in target users. PMID: 27115196 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - April 27, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

The Integrated Care of Asthma in Switzerland (INCAS)-study: Patients' perspective of received asthma care and their interest in asthma education.
CONCLUSIONS: More than half of the patients were interested in asthma education. Interest was associated with worse asthma control and lower receipt of care according to the Chronic Care Model. Considering these aspects help to improve care quality and allow targeting interventions to those patients, who are interested in becoming active participants in their care and who might benefit most. The study is registered at https://clinicaltrials.gov Identifier: NCT02425293. PMID: 27115047 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - April 27, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Does the Term "Deflators" Reflect More Accurately the Beneficial Effects of Long-acting Bronchodilators in COPD?
Authors: Kostikas K, Siafakas NM PMID: 27115572 [PubMed - as supplied by publisher] (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - April 27, 2016 Category: Respiratory Medicine Tags: COPD Source Type: research

The Selective JAK1/3-Inhibitor R507 Mitigates Obliterative Airway Disease Both With Systemic Administration and Aerosol Inhalation
Conclusions: The Janus kinase 1/3 inhibitor R507 is a very well-tolerated immunosuppressant that similarly diminished obliterative airway disease with systemic or inhaled administration. (Source: Transplantation)
Source: Transplantation - April 27, 2016 Category: Transplant Surgery Tags: Original Basic Science-General Source Type: research

Epidemiology and Outcomes of Nontuberculous Mycobacterial Infections in Solid Organ Transplant Recipients at a Midwestern Center
Conclusions: Among SOT patients, NTM were most frequently identified from lung transplant recipients. NTM infection was not associated with increased mortality, although NTM disease was associated with increased mortality compared with colonization in lung transplant recipients. (Source: Transplantation)
Source: Transplantation - April 27, 2016 Category: Transplant Surgery Tags: Original Basic Science-Liver Source Type: research

Acute exacerbations of COPD: reflections of an unfinished story
(Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 27, 2016 Category: Respiratory Medicine Authors: Cristiana Rafaela Lopes da Cruz, Pedro Ricardo Silva Santos, Antonio Matias Esquinas Rodriguez Tags: Letter to the Editor Source Type: research

Performance of manual hyperinflation: consistency and modification of the technique by intensive care unit nurses during physiotherapy
ConclusionsExperienced nurses were able to manually hyperinflate ‘normal' patients in a simulated setting safely. Despite their knowledge of barotrauma, unsafe airway pressures were delivered in some scenarios. Relevance to clinical practiceTraining with regard to safe airway pressures, breath hold and adequate volumes is recommended for all nurses undertaking the procedure. Nurses and physiotherapists must closely monitor the patient's condition during manual hyperinflation thereby recognising changes with regard to lung compliance and airway resistance, with nurses responding by altering their technique. The addition o...
Source: Journal of Clinical Nursing - April 27, 2016 Category: Nursing Authors: Diane M Dennis, Christine N Duncan, Mary Pinder, Charley A Budgeon, Wendy J Jacob Tags: Original Article Source Type: research

Practice and knowledge about diagnosis and treatment of alpha-1 antitrypsin deficiency in Spain and Portugal
Determining physicians’ awareness about alpha-1 antitrypsin (AAT) deficiency (AATD) may help to explain the discrepancy between the observed and expected number of patients diagnosed with this disease. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 27, 2016 Category: Respiratory Medicine Authors: Cristina Esquinas, Miriam Barrecheguren, Maria Sucena, Esther Rodriguez, Sandra Fernandez and Marc Miravitlles Source Type: research

Ultrathin bronchoscopy for solitary pulmonary lesions in a region endemic for tuberculosis: a randomised pilot trial
The evaluation of solitary pulmonary lesions (SPL) requires a balance between procedure-related morbidity and diagnostic yield, particularly in areas where tuberculosis (TB) is endemic. Data on ultrathin bronc... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 27, 2016 Category: Respiratory Medicine Authors: Daniel Franzen, Andreas H. Diacon, Lutz Freitag, Pawel T. Schubert, Colleen A. Wright and Macé M. Schuurmans Source Type: research

The relationship between exercise induced bronchial obstruction and health related quality of life in female and male adolescents from a general population
Previous studies have observed that exercise-induced bronchoconstriction (EIB) is more common and more strongly related to exercise related breathing problems in female adolescents than male adolescents. Howev... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 27, 2016 Category: Respiratory Medicine Authors: Henrik Johansson, Katarina Norlander, Christer Janson, Andrei Malinovschi, Leif Nordang and Margareta Emtner Source Type: research

Identification of vitamin D sensitive pathways during lung development
In this study, we aimed to identify the mechanisms linking vitamin D with lung development using a mouse model o... (Source: Respiratory Research)
Source: Respiratory Research - April 27, 2016 Category: Respiratory Medicine Authors: Ling Chen, Richard Wilson, Ellen Bennett and Graeme R. Zosky Source Type: research

Comparison of molecular detection methods for pertussis in children during a state-wide outbreak
A state-wide pertussis outbreak occurred in Washington during the winter–spring months of 2012, concurrent with respiratory viral season. We compared performance characteristics of a laboratory-developed pertu... (Source: Annals of Clinical Microbiology and Antimicrobials)
Source: Annals of Clinical Microbiology and Antimicrobials - April 27, 2016 Category: Microbiology Authors: X. Qin, D. M. Zerr, M. P. Kronman, A. L. Adler, J. E. Berry, S. Rich, A. M. Buccat, M. Xu and J. A. Englund Source Type: research

IgE serum concentration against airborne fungi in children with respiratory allergies
To evaluate total and specific E immunoglobulin (IgE) antibody concentrations in underage subjects with respiratory allergic diseases. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - April 27, 2016 Category: Allergy & Immunology Authors: Geusa Felipa de Barros Bezerra, Denise Maria Costa Haidar, Marcos Antonio Custódio Neto da Silva, Walbert Edson Muniz Filho, Ramon Moura dos Santos, Ivone Garros Rosa, Graça Maria de Castro Viana, Luís Zaror and Maria do Desterro Soares Brandão Nascim Source Type: research

Key mechanisms governing resolution of lung inflammation
Abstract Innate immunity normally provides excellent defence against invading microorganisms. Acute inflammation is a form of innate immune defence and represents one of the primary responses to injury, infection and irritation, largely mediated by granulocyte effector cells such as neutrophils and eosinophils. Failure to remove an inflammatory stimulus (often resulting in failed resolution of inflammation) can lead to chronic inflammation resulting in tissue injury caused by high numbers of infiltrating activated granulocytes. Successful resolution of inflammation is dependent upon the removal of these cells. Und...
Source: Seminars in Immunopathology - April 27, 2016 Category: Pathology Source Type: research

Assessment of the need for nitric oxide measurement in patients with respiratory diseases
Publication date: May 2016 Source:Respiratory Investigation, Volume 54, Issue 3 Author(s): Masakazu Ichinose (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 27, 2016 Category: Respiratory Medicine Source Type: research

Pirfenidone: Clinical trials and clinical practice in patients with idiopathic pulmonary fibrosis
Publication date: Available online 26 April 2016 Source:Respiratory Investigation Author(s): Masashi Bando Pirfenidone is an oral drug that exerts not only anti-fibrotic activity but also pleiotropic effects, such as anti-inflammatory and anti-oxidative effects. Because it suppresses reduction in vital capacity and improves progression-free survival, it was approved in October 2008 in Japan for the first time in the world as an anti-fibrotic agent for treatment of idiopathic pulmonary fibrosis (IPF). In October 2014, the agent was approved in the U.S., based on the results of the ASCEND study. Today, it is commercially ...
Source: Respiratory Investigation - April 27, 2016 Category: Respiratory Medicine Source Type: research

Possible effect of abatacept on the progression of interstitial lung disease in rheumatoid arthritis patients
Publication date: Available online 20 April 2016 Source:Respiratory Investigation Author(s): Tamao Nakashita, Katsutoshi Ando, Kazuhisa Takahashi, Shinji Motojima (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 27, 2016 Category: Respiratory Medicine Source Type: research

Choke point physiology in airway stenting: A case presentation and discussion
Conclusion To ensure correct stent positioning and thus optimal functional benefit, it is important to locate the exact position of tracheobronchial stenosis. (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 27, 2016 Category: Respiratory Medicine Source Type: research

Corrigendum to ‘‘High-flow nasal cannula oxygen therapy for acute exacerbation of interstitial pneumonia: A case series’’
Publication date: Available online 16 April 2016 Source:Respiratory Investigation Author(s): Yukihiro Horio, Takahisa Takihara, Kyoko Niimi, Masamichi Komatsu, Masako Sato, Jun Tanaka, Hiroto Takiguchi, Hiromi Tomomatsu, Katsuyoshi Tomomatsu, Naoki Hayama, Tsuyoshi Oguma, Takuya Aoki, Tetsuya Urano, Atsushi Takagi, Koichiro Asano (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 27, 2016 Category: Respiratory Medicine Source Type: research

Energy metabolic disorder is a major risk factor in severe influenza virus infection: Proposals for new therapeutic options based on animal model experiments
Publication date: Available online 4 April 2016 Source:Respiratory Investigation Author(s): Hiroshi Kido, Irene L. Indalao, Hyejin Kim, Takashi Kimoto, Satoko Sakai, Etsuhisa Takahashi Severe influenza is characterized by cytokine storm and multiorgan failure. Influenza patients with underlying diseases show a rapid progression in disease severity. The major mechanism that underlies multiorgan failure during the progressive stage of infection, particularly in patients with underlying risk factors, is mitochondrial energy crisis. The relationship between the factors that determine infection severity, such as influen...
Source: Respiratory Investigation - April 27, 2016 Category: Respiratory Medicine Source Type: research

Mutations in GAS8, A Gene Encoding A Nexin‐Dynein Regulatory Complex Subunit, Cause Primary Ciliary Dyskinesia With Axonemal Disorganization
This article is protected by copyright. All rights reserved (Source: Human Mutation)
Source: Human Mutation - April 27, 2016 Category: Genetics & Stem Cells Authors: Ludovic Jeanson, Lucie Thomas, Bruno Copin, André Coste, Isabelle Sermet‐Gaudelus, Florence Dastot‐Le Moal, Philippe Duquesnoy, Guy Montantin, Nathalie Collot, Sylvie Tissier, Jean‐François Papon, Annick Clement, Bruno Louis, Estelle Escudier, Ser Tags: Research Article Source Type: research

Research on AIDS Patients’ Survival Time after Highly Active Antiretroviral Therapy, Treatment Effect and Treatment Modes
Publication date: Available online 26 April 2016 Source:Saudi Pharmaceutical Journal Author(s): Riying Lv, Guojian Li, jizhou Wu, Yujia Zhu, XiongLin Qin, Shixiong Li To fully define clinical efficacy of highly active antiretroviral therapy for AIDS, analyze patients’ survival time and treatment mode after receiving treatment, and provide scientific theory to guide improvement of antiviral therapy, this paper selected 3100 cases of patients diagnosed with AIDS during April 2006 and April 2014 as object of this study. All patients were treated with highly active antiretroviral therapy. The main analysis contents o...
Source: Saudi Pharmaceutical Journal - April 27, 2016 Category: Drugs & Pharmacology Source Type: research

Secondary peripheral ameloblastic carcinoma of the palate: A case report and literature review
We describe the case of an 82-year-old male referred to our department with a hemorrhagic mass on the right palate that developed 6–7 years earlier. Clinical examination revealed a mass 40×30×10mm in size affecting the hard palate that exhibited relatively clear boundaries, granular superficial appearance, and hemorrhaging. Computed tomography and magnetic resonance imaging revealed compressive resorption of the bone surface in contact with the tumor. A biopsy was performed; the histopathological diagnosis of the biopsy was peripheral ameloblastoma without any findings of malignancy. The patient subsequently underwent ...
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - April 27, 2016 Category: ENT & OMF Source Type: research

Middle East respiratory syndrome in South Korea during 2015: Risk-related perceptions and quarantine attitudes
Publication date: Available online 26 April 2016 Source:American Journal of Infection Control Author(s): E.Y. Kim, Q. Liao, E.S. Yu, J.H. Kim, S.W. Yoon, W.W.T. Lam, R. Fielding A telephone survey involving 200 household members in and around Seoul, South Korea, was completed during the maturity stage of the outbreak of Middle East respiratory syndrome (MERS) in Korea during June 2015. The study found that respondents perceived low risk from contracting MERS, had low trust in government in controlling MERS, and generally held unfavorable attitudes toward quarantine. (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - April 27, 2016 Category: Infectious Diseases Source Type: research

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial
Publication date: Available online 27 April 2016 Source:The Lancet Author(s): Sally Wenzel, Mario Castro, Jonathan Corren, Jorge Maspero, Lin Wang, Bingzhi Zhang, Gianluca Pirozzi, E Rand Sutherland, Robert R Evans, Vijay N Joish, Laurent Eckert, Neil M H Graham, Neil Stahl, George D Yancopoulos, Mariana Louis-Tisserand, Ariel Teper Background Dupilumab, a fully human anti-interleukin-4 receptor α monoclonal antibody, inhibits interleukin-4 and interleukin-13 signalling, key drivers of type-2-mediated inflammation. Adults with uncontrolled persistent asthma who are receiving medium-to-high-dose inhaled c...
Source: The Lancet - April 27, 2016 Category: Journals (General) Source Type: research

Oral pressure therapy (winx) for obstructive sleep apnea: a meta-analysis updating the systematic review
(Source: Sleep and Breathing)
Source: Sleep and Breathing - April 27, 2016 Category: Respiratory Medicine Source Type: research

Lung cancer in patients diagnosed with silicosis should be investigated
Publication date: Available online 27 April 2016 Source:Respiratory Medicine Case Reports Author(s): Adil Can Güngen, Yusuf Aydemir, Hikmet Çoban, Hasan Düzenli, Canantan Tasdemir Silicosis is an interstitial lung disease developing as a result of inhalation of inorganic silica particles. In silicosis cases developing as a result of environmental and occupational exposure, an increase is observed in Turkey especially depending upon denim sandblasting. We present a 35-year-old female case who was applied to our hospital due to complaint of progressive dyspnea, had a history of working in denim sandblasting for 18 ...
Source: Respiratory Medicine Case Reports - April 27, 2016 Category: Respiratory Medicine Source Type: research

Elemental analysis of occupational granulomatous lung disease by electron probe microanalyzer with wavelength dispersive spectrometer: Two case reports
We reported two cases of granulomatous lung disease with occupational exposure to metal dusts other than beryllium. They had worked in the battery manufacturing industry for 7 years and in an aluminum-processing factory for 6 years, respectively. Chest high-resolution computed tomography showed diffuse micronodules, and histology of video-assisted lung biopsy specimens revealed granulomatous lesions in the pulmonary interstitium. Results of microscopic examination of the tissue with special stains for mycobacteria and fungi were negative. Analysis by an electron probe microanalyzer with a wavelength-dispersive spectrometer...
Source: Respiratory Medicine Case Reports - April 27, 2016 Category: Respiratory Medicine Source Type: research

Intra-operative adherence to lung-protective ventilation: a prospective observational study
Conclusions Perioperative lung protection ventilation can improve patient outcomes from major surgery. This large prospective study demonstrates that within the West Midlands lung-protective ventilation during the perioperative period is uncommon, especially in relation to the use of PEEP, and that perhaps further trials are required to promote wider adoption of practice. (Source: Perioperative Medicine)
Source: Perioperative Medicine - April 27, 2016 Category: Surgery Source Type: research

Effects of internal iliac artery embolization on systemic inflammatory response syndrome in dogs with simulated-pelvic-fracture combined with massive bleeding
Conclusion Through the use of an on-spot interventional treatment cabin, early internal iliac artery embolization can control bleeding associated with pelvic fractures, delay the occurrence of SIRS, and improve the success rate of the treatment of pelvic fracture combined with bleeding. (Source: Military Medical Research)
Source: Military Medical Research - April 27, 2016 Category: Global & Universal Source Type: research