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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

Plugs of the Air Passages: A Clinicopathologic Review.
Abstract Although mucus is a normal product of the tracheobronchial tree, some diseases of the respiratory tract are characterized by unusually thick (inspissated) forms of mucus that accumulate within the airways. These are known as mucus plugs. The pathologic composition of these plugs is surprisingly diverse and, in many cases, correlates with distinctive clinical, radiologic, and bronchoscopic findings. The best-known conditions that involve mucus plugs are allergic bronchopulmonary aspergillosis, plastic bronchitis, and asthma. Other lung diseases occasionally associated with plugs within the airways include A...
Source: Chest - July 18, 2016 Category: Respiratory Medicine Authors: Panchabhai TS, Mukhopadhyay S, Sehgal S, Bandyopadhyay D, Erzurum SC, Mehta AC Tags: Chest Source Type: research

[Reliability of the PROFUND index to predict 4-year mortality in polypathological patients].
CONCLUSIONS: The PROFUND index is a reliable tool for predicting long-term global mortality in polypathological patients from Internal Medicine but not from Geriatrics departments. PMID: 27422735 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - July 17, 2016 Category: Journals (General) Tags: Med Clin (Barc) Source Type: research

Oxidative Stress and Genetic Variants of Xenobiotic-Metabolising Enzymes Associated with COPD Development and Severity in Serbian Adults.
In conclusion, early identification of GSTM1*null or GSTT1*null genotypes in females, low mEH activity phenotype in heavy smokers and monitoring of oxidative stress level can be useful diagnostic and prognostic biomarkers. PMID: 27421065 [PubMed - as supplied by publisher] (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - July 17, 2016 Category: Respiratory Medicine Tags: COPD Source Type: research

Adherence to Long-Acting Bronchodilators After Discharge for COPD: How Much of the Geographic Variation is Attributable to the Hospital of Discharge and How Much to the Primary Care Providers?
Authors: Di Martino M, Ventura M, Cappai G, Lallo A, Davoli M, Agabiti N, Fusco D Abstract In moderate-severe chronic obstructive pulmonary disease (COPD), long-acting bronchodilators (LBs) are recommended to improve the quality of life. The aims of this study were to measure adherence to LBs after discharge for COPD, identify determinants of adherence, and compare amounts of variation attributable to hospitals of discharge and primary care providers, i.e. local health districts (LHDs) and general practitioners (GPs). This cohort study was based on the Lazio region population, Italy. Patients discharged in 2007-201...
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - July 17, 2016 Category: Respiratory Medicine Tags: COPD Source Type: research

Trends in Outcomes, Financial Burden, and Mortality for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) in the United States from 2002 to 2010.
Authors: Jinjuvadia C, Jinjuvadia R, Mandapakala C, Durairajan N, Liangpunsakul S, Soubani AO Abstract Chronic obstructive pulmonary disease (COPD) is the cause of substantial economic and social burden. We evaluated the temporal trends of hospitalizations from acute exacerbation of COPD and determined its outcome and financial impact using the National (Nationwide) Inpatient Sample (NIS) databases (2002-2010). Individuals aged ≥ 18 years were included. Subjects who were hospitalized with primary diagnosis of COPD exacerbation and those who were admitted for other causes but had underlying acute exacerbation of ...
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - July 17, 2016 Category: Respiratory Medicine Tags: COPD Source Type: research

Modulation of Host Immunity by the Human Metapneumovirus.
Abstract Globally, as a leading agent of acute respiratory tract infections in children <5 years of age and the elderly, the human metapneumovirus (HMPV) has gained considerable attention. As inferred from studies comparing vaccinated and experimentally infected mice, the acquired immune response elicited by this pathogen fails to efficiently clear the virus from the airways, which leads to an exaggerated inflammatory response and lung damage. Furthermore, after disease resolution, there is a poor development of T and B cell immunological memory, which is believed to promote reinfections and viral spread in the ...
Source: Clinical Microbiology Reviews - July 17, 2016 Category: Microbiology Authors: Céspedes PF, Palavecino CE, Kalergis AM, Bueno SM Tags: Clin Microbiol Rev Source Type: research

Respiratory syncytial virus outbreak on an adult stem cell transplant unit
Conclusions High vigilance for respiratory viruses on high-risk inpatient units is required for detection and prevention of potential outbreaks. Multiple respiratory viruses with outbreak potential were identified among HCWs. HCWs with respiratory virus symptoms should not provide direct patient care. Absence of lower respiratory tract infection suggests lower virulence of RSV-B, compared with respiratory syncytial virus type A, among immunocompromised adults. (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - July 17, 2016 Category: Infectious Diseases Source Type: research

Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin
In conclusion, we identify griffithsin as a potent inhibitor of MERS-CoV infection at the entry step. (Source: Antiviral Therapy)
Source: Antiviral Therapy - July 17, 2016 Category: Virology Source Type: research

Chapter 63 Metabolic, endocrine, and other genetic disorders
Publication date: 2016 Source:Handbook of Clinical Neurology, Volume 136 Author(s): Hisham M. Dahmoush, Elias R. Melhem, Arastoo Vossough Metabolic, endocrine, and genetic diseases of the brain include a very large array of disorders caused by a wide range of underlying abnormalities and involving a variety of brain structures. Often these disorders manifest as recognizable, though sometimes overlapping, patterns on neuroimaging studies that may enable a diagnosis based on imaging or may alternatively provide enough clues to direct further diagnostic evaluation. The diagnostic workup can include various biochemical la...
Source: Handbook of Clinical Neurology - July 17, 2016 Category: Neurology Source Type: research

Bilateral Stage I Chronic Maxillary Atelectasis: A Case Report
Conclusion The present literature regarding CMA is incomplete and further investigation is required to provide greater insight into its aetiology and pathogenesis. Minimally invasive endoscopic approaches can be employed to re-establish aeration to the affected maxillary sinus for symptomatic relief, to halt disease progression and facilitate antral remodelling and sinus re-expansion. (Source: International Journal of Surgery Case Reports)
Source: International Journal of Surgery Case Reports - July 17, 2016 Category: Surgery Source Type: research

Flow-based sorting of neonatal lymphocyte populations for transcriptomics analysis.
Abstract RATIONALE: Emerging data suggest an important role for T lymphocytes in the pathogenesis of chronic lung disease in preterm infants. Comprehensive assessment of the lymphocyte transcriptome may identify biomarkers and mechanisms of disease. METHODS: Small volume peripheral blood samples were collected from premature infants enrolled with consent in the Prematurity and Respiratory Outcomes Program (PROP), at the time of discharge from the hospital. Blood samples were collected at two sites and shipped to a central laboratory for processing. Peripheral blood mononuclear cells (PBMCs) were isolated by Fic...
Source: Journal of Immunological Methods - July 17, 2016 Category: Allergy & Immunology Authors: Misra RS, Bhattacharya S, Huyck HL, Wang JE, Slaunwhite CG, Slaunwhite SL, Wightman TR, Secor-Socha S, Misra SK, Bushnell TP, Reynolds AM, Ryan RM, Quataert SA, Pryhuber GS, Mariani TJ Tags: J Immunol Methods Source Type: research

Exome sequencing in Thai patients with familial obesity.
Abstract Obesity is a major worldwide health issue, with increasing prevalence in adults and children from developed and developing countries. Obesity causes several chronic diseases, including cardiovascular and respiratory diseases, osteoarthritis, hypertension, stroke, type II diabetes, obstructive sleep apnea, and several types of cancer. Previous genome-wide association studies have identified several genes associated with obesity, including LEP, LEPR, POMC, PCSK1, FTO, MC3R, MC4R, GNPDA2, TMEM18, QPCTL/GIPR, BDNF, ETV5, MAP2K5/SKOR1, SEC16B, SIM1, and TNKS/MSRA. However, most of these variants are found in th...
Source: Genetics and Molecular Research - July 16, 2016 Category: Genetics & Stem Cells Authors: Kaewsutthi S, Santiprabhob J, Phonrat B, Tungtrongchitr A, Lertrit P, Tungtrongchitr R Tags: Genet Mol Res Source Type: research

Genetic and genomic basis of antibody response to porcine reproductive and respiratory syndrome (PRRS) in gilts and sows.
CONCLUSIONS: Moderate genomic prediction accuracies can be obtained for PRRS antibody response using SNPs located within two major QTL on SSC7, while the rest of the genome showed limited predictive ability. Results were obtained using data from multiple genetic sources and farms, which further strengthens these findings. Further research is needed to validate the use of S/P ratio as an indicator trait for reproductive performance during PRRS outbreaks. PMID: 27417876 [PubMed - in process] (Source: Genet Sel Evol)
Source: Genet Sel Evol - July 16, 2016 Category: Genetics & Stem Cells Authors: Serão NV, Kemp RA, Mote BE, Willson P, Harding JC, Bishop SC, Plastow GS, Dekkers JC Tags: Genet Sel Evol Source Type: research

Electromyography-Guided Botulinum Toxin Injection Into the Cricothyroid Muscles in Bilateral Vocal Fold Abductor Paralysis.
Conclusion: After BTX injection, improvements in the mean Borg score, PEF and FIV1 values and SF-36 sub-scale scores showed the restricted success of this approach. This modality may be kept in mind as a transient treatment option for patients refused persistent tracheotomy or ablative airway surgeries. PMID: 27416735 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - July 16, 2016 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Characterization of G970-T1122del CFTR mutation found in Japanese CF patients
Cystic Fibrosis Transmembrane conductance Regulator (CFTR) anion channels are expressed on the luminal membrane of pancreatic ductal epithelia and play a main role in the bicarbonate-rich pancreatic juice secretion. CFTR dysfunctions due to gene mutations cause cystic fibrosis (CF), a life threatening genetic disorder with severe pancreatic insufficiency as well as lethal respiratory disorder. CF is very rare among Asians whereas Caucasian who has a large CF population, e.g., F508del mutation with one heterozygote per twenty-five. (Source: Pancreatology)
Source: Pancreatology - July 16, 2016 Category: Gastroenterology Authors: Kanako Nakao, Miyuki Nakakuki, Hiroshi Ishiguro, Yoshiro Sohma Source Type: research

Key Molecular Mechanisms of Chaiqinchengqi Decoction in Alleviating the Pulmonary Albumin Leakage Caused by Endotoxemia in Severe Acute Pancreatitis Rats.
Authors: Wu W, Luo R, Lin Z, Xia Q, Xue P Abstract To reveal the key molecular mechanisms of Chaiqinchengqi decoction (CQCQD) in alleviating the pulmonary albumin leakage caused by endotoxemia in severe acute pancreatitis (SAP) rats. Rats models of SAP endotoxemia-induced acute lung injury were established, the studies in vivo provided the important evidences that the therapy of CQCQD significantly ameliorated the increases in plasma levels of lipopolysaccharide (LPS), sCd14, and Lbp, the elevation of serum amylase level, the enhancements of systemic and pulmonary albumin leakage, and the depravation of airways ind...
Source: Evidence-based Complementary and Alternative Medicine - July 16, 2016 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

In memoriam Christian Boutin (1933-2015).
Authors: Astoul P PMID: 27408941 [PubMed - in process] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - July 16, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Diagnosis and Treatment of Diaphragmatic Dysfunction].
Authors: Windisch W, Schönhofer B, Magnet FS, Stoelben E, Kabitz HJ Abstract There are many reasons for an impairment of the diaphragmatic function potentially affecting all components of the respiratory pump. Particularly, diagnosis and treatment of unilateral and bilateral phrenic nerve paralysis are challenging. Neuromuscular disorders, trauma, iatrogenic conditions, tumor compression, but also infectious and inflammatory conditions in addition to neuralgic amyotrophy and idiopathic phrenic nerve paralysis are reasons for phrenic nerve paralysis. Primarily, diagnostic procedures include the anamnesis, physical ...
Source: Pneumologie - July 16, 2016 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

Generalized Convulsion Complicating Acute Diffuse Pulmonary Hemorrhage: The Report of a Rare Case.
CONCLUSION: The disease entity of acute diffuse pulmonary hemorrhage is similar to neurogenic pulmonary edema. Physicians should be aware of this extremely rare but life-threatening complication, namely seizure-related acute diffuse pulmonary hemorrhage. The patient's response to respiratory support and corticosteroid is usually quite satisfactory. PMID: 27411798 [PubMed - in process] (Source: Acta Neurologica Taiwanica)
Source: Acta Neurologica Taiwanica - July 16, 2016 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Serratus Anterior Plane (SAP) Block Used for Thoracotomy Analgesia: A Case Report.
Authors: Okmen K, Okmen BM, Uysal S Abstract Thoracotomy is a surgical technique used to reach the thoracic cavity. Management of pain due to thoracotomy is important in order to protect the operative respiratory reserves and decrease complications. For thoracotomy pain, blocks (such as thoracic epidural, paravertebral, etc.) and pleural catheterization and intravenous drugs (such as nonsteroidal anti-inflammatory drugs [NSAIDs], and opioids, etc., can be used. We performed a serratus anterior plane (SAP) block followed by catheterization for thoracotomy pain. We used 20 ml 0.25% bupivacaine for analgesia in a pati...
Source: Korean Journal of Pain - July 16, 2016 Category: Anesthesiology Tags: Korean J Pain Source Type: research

Comparison of growth, infections and feeding habits among formula-fed infants starting complementary feeding at 4 to 6 months old with those starting at 6 months old.
In conclusion, for formula-fed infants, age of onset of complementary feeding was not associated with infant growth or infection rates. However, some feeding habits differed between the two groups. It is unclear if the age of introducing complementary feeding caused these differences or was merely associated with these differences. PMID: 27405135 [PubMed - in process] (Source: Southeast Asian Journal of Tropical Medicine and Public Health)
Source: Southeast Asian Journal of Tropical Medicine and Public Health - July 16, 2016 Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research

Cd4 lymphocytopenia without hiv infection.
We report the case of a 82-year-old female who presented with a markedly low CD4 count during a severe lower respiratory tract infection and respiratory failure without HIV infection. The total lymphocyte and the absolute CD4 counts are 255/mm³ and 109/mm³, respectively. Sputum and bronchial lavage fluid were both negative for acid-fast bacilli. The anti-HIV antibody test was negative.The blood culture was also negative. She had no history of diabetes, malnutrition or chronic kidney disease. Because pneumocystis jiroveci pneumonia could not be excluded, she was treated with a combination of clindamycin, dexamethasone, pr...
Source: Southeast Asian Journal of Tropical Medicine and Public Health - July 16, 2016 Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research

Nasopharyngeal carriage of streptococcus pneumoniae in healthy children under five years old in central lombok regency, indonesia.
NASOPHARYNGEAL CARRIAGE OF STREPTOCOCCUS PNEUMONIAE IN HEALTHY CHILDREN UNDER FIVE YEARS OLD IN CENTRAL LOMBOK REGENCY, INDONESIA. Southeast Asian J Trop Med Public Health. 2016 May;47(3):485-93 Authors: Hadinegoro SR, Prayitno A, Khoeri MM, Djelantik IG, Dewi NE, Indriyani SA, Muttaqin Z, Mudaliana S, Safari D Abstract Colonization with Streptococcus pneumoniae is mostly symptomless, but can progress to respiratory or even systemic disease. We investigated nasopharyngeal carriage of Streptococcus pneumoniae in healthy children under five years of age in Central Lombok Regency, Indonesia. This cross se...
Source: Southeast Asian Journal of Tropical Medicine and Public Health - July 16, 2016 Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research

Prevalence, antibiotic and pulsed-field gel electrophoresis patterns of staphylococcus aureus small-colony variants in cystic fibrosis patients.
In this study, we aimed to determine the prevalence, antibiotic susceptibility and genotypic property of S. aureus SCVs in respiratory tract samples of CF patients admitted to Istanbul Faculty of Medicine Hospital, Turkey. Among 305 respiratory tract samples from 84 CF patients, normal S. aureus isolates were present in 71% of the CF patients and S. aureus SCVs in 21%. The highest antibiotic resistance was against penicillin (82%) followed by clarithromycin (21%) in S. aureus SCVs, while resistance to levofloxacin was low (2%) in normal S. aureus isolates but was 16% in S. aureus SCVs. No mecA and mecC were detected. The S...
Source: Southeast Asian Journal of Tropical Medicine and Public Health - July 16, 2016 Category: Tropical Medicine Tags: Southeast Asian J Trop Med Public Health Source Type: research

Re: "a new time-series methodology for estimating relationships between elderly frailty, remaining life expectancy, and ambient air quality".
Authors: Goldberg MS, Burnett RT PMID: 27411848 [PubMed - as supplied by publisher] (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - July 16, 2016 Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research

Asthma in British Columbia: Are We Finally Breathing Easier? A population based study of the burden of disease Over 14 Years.
CONCLUSIONS: In BC, the incidence and prevalence of asthma has remained stable over 14 years. While health service utilization declined, there is variation between rural and urban regions. PMID: 27414432 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - July 16, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Adult asthma is associated with an increased risk of herpes zoster: A population-based cohort study.
CONCLUSIONS: Newly diagnosed adult patients with asthma have a significantly higher risk of developing HZ than do those without asthma. PMID: 27410999 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - July 16, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Linguistic validation of stigmatisation degree, self-esteem and knowledge questionnaire among asthma patients using Rasch analysis.
CONCLUSION: The translated "Stigmatisation Degree, Self-Esteem and Knowledge Questionnaire" showed high real item reliability values of 0.90, 0.86 and 0.89 for stigmatisation degree, self-esteem, and knowledge of asthma, respectively. Furthermore, all values of point measure correlation (PTMEA Corr) analysis were within the acceptable specified range of the Rasch model. Infit / outfit mean square values and Z standard (ZSTD) values of each item verified the construct validity and suggested retaining all the items in the questionnaire. The reliability analyses and output tables of item measures for construct validation prov...
Source: Journal of Asthma - July 16, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Detection and quantification of epithelial progenitor cell populations in human healthy and IPF lungs
In the human lung, epithelial progenitor cells in the airways give rise to the differentiated pseudostratified airway epithelium. In mice, emerging evidence confers a progenitor function to cytokeratin 5 (KRT5+) ... (Source: Respiratory Research)
Source: Respiratory Research - July 16, 2016 Category: Respiratory Medicine Authors: N. F. Smirnova, A. C. Schamberger, S. Nayakanti, R. Hatz, J. Behr and O. Eickelberg Source Type: research

Alveolar Macrophages Can Control Respiratory Syncytial Virus Infection in the Absence of Type I Interferons
In this study, primary AMs from MAVS (Mavs-/-)- or type I IFN receptor (Ifnar1-/-)-deficient mice were exposed to RSV ex vivo. Wild-type (wt) AMs but not Mavs-/- and Ifnar1-/- AMs produced inflammatory mediators in response to RSV. Furthermore, Mavs-/- and Ifnar1-/- AMs accumulated more RSV proteins than wt AMs, but the infection was abortive. Thus, RIG-I-like receptor-MAVS and IFNAR signalling are important for the induction of proinflammatory mediators from AMs upon RSV infection, but this signalling is not central for controlling viral replication. The ability to restrict viral replication makes AMs ideal sensors of RSV...
Source: Journal of Innate Immunity - July 16, 2016 Category: Allergy & Immunology Source Type: research

Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization.
Authors: Steven A, Leisz S, Sychra K, Hiebl B, Wickenhauser C, Mougiakakos D, Kiessling R, Denkert C, Seliger B Abstract The cAMP-responsive element-binding protein (CREB) is involved in the tumorigenicity of HER-2/neu-overexpressing murine and human tumor cells, but a link between the HER-2/neu-mediated CREB activation, its posttranslational modification and localization and changes in the cellular metabolism, due to an altered (tumor) microenvironment remains to be established. The present study demonstrated that shRNA-mediated silencing of CREB in HER-2/neu-transformed cells resulted in decreased tumor formation...
Source: Oncotarget - July 16, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Sucrose for analgesia in newborn infants undergoing painful procedures.
CONCLUSIONS: Sucrose is effective for reducing procedural pain from single events such as heel lance, venipuncture and intramuscular injection in both preterm and term infants. No serious side effects or harms have been documented with this intervention. We could not identify an optimal dose due to inconsistency in effective sucrose dosage among studies. Further investigation of repeated administration of sucrose in neonates is needed. There is some moderate-quality evidence that sucrose in combination with other non-pharmacological interventions such as non-nutritive sucking is more effective than sucrose alone, but more ...
Source: Cochrane Database of Systematic Reviews - July 16, 2016 Category: Journals (General) Authors: Stevens B, Yamada J, Ohlsson A, Haliburton S, Shorkey A Tags: Cochrane Database Syst Rev Source Type: research

Evaluation of Indian sheep breeds of arid zone under heat stress condition
Publication date: Available online 15 July 2016 Source:Small Ruminant Research Author(s): K. Mahesh Singh, Sanjeev Singh, Indrajit Ganguly, Anita Ganguly, K.N. Raja, Ashish Chopra, H.K. Narula The present study was conducted to assess the effect of the heat stress on the hematological and physio-biochemical parameters of sheep breeds thriving in hot and arid climatic conditions. Thirty animals (female) of about one and half year of age from each sheep breed (Chokla, Magra and Marwari) were used for the estimation of hematological and physio-biochemical parameters under normal (lower Temperature Humidity Index of 6...
Source: Small Ruminant Research - July 16, 2016 Category: Zoology Source Type: research

Are there differences in outcome after elective sigmoidectomy for diverticular disease and for cancer? A national inpatient study
Conclusionalthough elective sigmoidectomy for diverticular disease has a higher risk of infective complications, elective sigmoidectomy for cancer has a higher risk of anastomotic leakage.This article is protected by copyright. All rights reserved. (Source: Colorectal Disease)
Source: Colorectal Disease - July 16, 2016 Category: Gastroenterology Authors: Mohammed Iyoob Mohammed Ilyas, Bardiya Zangbar, Valentine N Nfonsam, Felipe A Maegawa, Bellal A Joseph, Jitesh A Patel, Steven D Wexner Tags: Original Article Source Type: research

Erratum to: In Vitro Activity of Oral Antimicrobial Agents against Pathogens Associated with Community-Acquired Upper Respiratory Tract and Urinary Tract Infections: A Five Country Surveillance Study
(Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - July 16, 2016 Category: Infectious Diseases Source Type: research

Viral colonization in exhaled breath condensate of lung cancer patients: Possible role of EBV and CMV
Conclusion: EBV and CMV resulted detectable in the EBC. In consideration of the potential involvement of these viruses in lung cancer, which was confirmed in this study, we support future studies in this direction. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - July 16, 2016 Category: Respiratory Medicine Authors: Giovanna E Carpagnano, Donato Lacedonia, Maria Iole Natalicchio, Grazia Cotugno, Luigi Zoppo, Domenico Martinelli, Raffaele Antonetti, Maria Pia Foschino‐Barbaro Tags: Original Article Source Type: research

Determinants of delay in tuberculosis diagnosis in Hamadan province, 2006−2014
Conclusion A high proportion of patients had delays in diagnosis exceeding three months. Our findings suggest that male gender, new cases, positive and extra pulmonary cases might increase the risk for delayeddiagnosis among TB patients. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - July 16, 2016 Category: Respiratory Medicine Source Type: research

Role of IOS in evaluation of patients with interstitial lung diseases
This study included 48 patients with interstitial lung diseases of different causes. Pulmonary function test by spirometry was done to measure FEV1, FVC, FEV1/FVC, MEF25-75 and pulmonary function test by impulse oscillometry (IOS). We measured R5, R20, X5, RF. Oxygen saturation and 6MWT. Results In our study 87% were females. The mean age in our study was 50.75±11.1. Mean X5 was low in ILD denoting restrictive pattern, and there was a negative correlation between X5andFEV1/FVC. There was a positive correlation between X5and6MWT. The mean R5 was 150.33±while mean R20 was 108.33±48.66 this is within normal then this is c...
Source: Egyptian Journal of Chest Diseases and Tuberculosis - July 16, 2016 Category: Respiratory Medicine Source Type: research

Predictive value of different scoring systems for critically ill patients with hospital acquired pneumonia
Conclusions SMART – cop score is the most sensitive score in predicting 28-day mortality in the studied patient followed by SMART – co and PSI score). SMART-cop score is the most specific one (Specificity=93%) in followed by Modified ATS score (Specificity=90%). (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - July 16, 2016 Category: Respiratory Medicine Source Type: research

Study of risk factors for pulmonary tuberculosis among diabetes mellitus patients
Conclusion From the current work it could be concluded that the factors determinant of pulmonary tuberculosis among diabetics are weight loss, decreased BMI, drug addiction, uncontrolled diabetes, higher rates of HbA1c, increased insulin requirements, anemia, higher ESR, higher platelet count and decreased serum proteins and albumin. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - July 16, 2016 Category: Respiratory Medicine Source Type: research

Role of glutathione S-transferase P-1 (GSTP-1) gene polymorphism in COPD patients
Conclusion There is a significant association between GSTP1 gene polymorphism and the development of COPD, and smoking have a role in GSTP1 gene polymorphism. The polymorphism has no relation to disease severity. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - July 16, 2016 Category: Respiratory Medicine Source Type: research

Can continuous positive air way pressure reverse carotid artery atherosclerosis in obstructive sleep apnea?
Conclusion CPAP significantly reduced CIMT in OSA patients. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - July 16, 2016 Category: Respiratory Medicine Source Type: research