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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

Exploring carer perceptions of training in out‐of‐hospital use of buccal midazolam for emergency management of seizures (2008–2012)
ConclusionsTraining for out‐of‐hospital use of buccal midazolam was considered valuable by carers. Only a third of the sample subsequently used midazolam. Half of these carers reported problems in administration and one reported respiratory difficulty. These results highlight the importance of drug safety and efficacious training programmes. (Source: Journal of Paediatrics and Child Health)
Source: Journal of Paediatrics and Child Health - January 15, 2015 Category: Pediatrics Authors: Anne M Connolly, Erin Beavis, Beatrice Mugica‐Cox, Ann ME Bye, John A Lawson Tags: Original Article Source Type: research

Demographic, clinical, and laboratory parameters of cystic fibrosis during the last two decades: a comparative analysis
Conclusion: Clinical outcomes differed between the two decades. Demographic, clinical, and laboratory markers in patients with CF are useful tools and should be encouraged in CF referral centers to determine the results of CF management and treatment, enabling a better understanding of this disease and its clinical evolution. Early diagnosis and management of CF will improve patients' quality of life and life expectancy until personalized drug therapy is possible for all patients with CF. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Fernando MarsonTais HortencioKatia AguiarJose Ribeiro Source Type: research

Comparison of Newcastle disease vaccine administered as powder or liquid in relation to the serum antibody response and adverse vaccinal reactions in broilers.
Abstract Liquid spray and aerosol mass vaccination of poultry have several drawbacks, such as uncontrolled deposition of vaccine particles in the respiratory tract and vaccine virus inactivation by formation and evaporation of droplets. These may be addressed by using dry powder vaccines with defined particle size distribution targeting the upper (primary vaccination) or the entire respiratory tract (booster vaccination). Therefore, a coarse Newcastle Disease (LZ58 strain) powder vaccine was administered to SPF broiler hens to compare the antibody response and adverse vaccinal reactions with those induced by a coar...
Source: Avian Pathology - January 15, 2015 Category: Pathology Authors: Landman WJ, Huyge K, Remon JP, Vervaet C, van Eck JH Tags: Avian Pathol Source Type: research

[Prevalence of glaucoma in obstructive sleep apnea.]
CONCLUSION: The data from this study shed doubt on a causal relationship between obstructive sleep apnea and glaucoma. PMID: 25585796 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe)
Source: Der Ophthalmologe - January 15, 2015 Category: Opthalmology Authors: Gross NJ, Funk J, Pache M, van der List M, Laubmann-Volz A, Sorichter S, Lagrèze WA Tags: Ophthalmologe Source Type: research

Divergent, Coexisting, Pseudomonas aeruginosa Lineages in Chronic Cystic Fibrosis Lung Infections.
Conclusions Our population-level analysis demonstrates that coexistence of distinct lineages of Pseudomonas aeruginosa Liverpool Epidemic Strain within individuals is common. In several cases, coexisting lineages may have been present in the infecting inoculum or assembled through multiple transmissions. Divergent lineages can share mutations via homologous recombination, potentially aiding adaptation to the airway during chronic infection. The genetic diversity of this transmissible strain within infections, revealed by high-resolution genomics, has implications for patient segregation and therapeutic strategies. PMID...
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Williams D, Evans B, Haldenby S, Walshaw MJ, Brockhurst MA, Winstanley C, Paterson S Tags: Am J Respir Crit Care Med Source Type: research

Blue Journal Conference: Aging and the Susceptibility to Lung Disease.
Abstract The aging of the population in the US and throughout the developed world has increased morbidity and mortality attributable to lung disease, while the morbidity and mortality from other prevalent diseases has declined or remained stable. Recognizing the importance of aging in the development of lung disease, the American Thoracic Society (ATS) highlighted this topic as a core theme for the 2014 annual meeting. The relationship between aging and lung disease was discussed in several oral symposiums and poster sessions at the annual ATS meeting. In this article, we used the input gathered the conference to d...
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Thannickal VJ, Murthy M, Balch WE, Chandel NS, Meiners S, Eickelberg O, Selman M, Pardo A, White ES, Levy BD, Busse PJ, Tuder RM, Antony VB, Sznajder JI, Budinger GR Tags: Am J Respir Crit Care Med Source Type: research

Long-Term Exposure to Traffic Emissions and Fine Particulate Matter and Lung Function Decline in the Framingham Heart Study.
Conclusions: Long-term exposure to traffic and PM2.5, at relatively low levels, were associated with lower FEV1 and FVC and an accelerated rate of lung function decline. PMID: 25590631 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Rice MB, Ljungman PL, Wilker EH, Dorans KS, Gold DR, Schwartz J, Koutrakis P, Washko GR, O'Connor GT, Mittleman MA Tags: Am J Respir Crit Care Med Source Type: research

Other therapies for sleep apnea.
Authors: PMID: 25590163 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Tags: Am J Respir Crit Care Med Source Type: research

Reply: IL-33-Dependent Type 2 Inflammation in Asthma Exacerbations.
PMID: 25590162 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Jackson DJ Tags: Am J Respir Crit Care Med Source Type: research

IL-33-Dependent Type 2 Inflammation in Asthma Exacerbations.
PMID: 25590161 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Kumar RK, Herbert C Tags: Am J Respir Crit Care Med Source Type: research

IL-33-Dependent Th2 Response after Rhinovirus Infection in Asthma: More Information Needed.
PMID: 25590160 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Hilvering B, Xue L, Pavord ID Tags: Am J Respir Crit Care Med Source Type: research

Measurement of serum calprotectin in stable patients predicts exacerbation and lung function decline in cystic fibrosis.
PMID: 25590159 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Reid PA, McAllister DA, Boyd AC, Innes JA, Porteous D, Greening AP, Gray RD Tags: Am J Respir Crit Care Med Source Type: research

Development of a Hypercoagulable Status in Patients Undergoing Off-Pump Lung Transplantation despite Prolonged Conventional Coagulation Tests.
PMID: 25590158 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Ruitenbeek K, Hugenholtz GC, Adelmeijer J, Pereboom IT, Meijers JC, van der Bij W, Porte RJ, Erasmus ME, Lisman T Tags: Am J Respir Crit Care Med Source Type: research

A Solemn Declaration from the World Alliance against Antibiotic Resistance.
PMID: 25590157 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Carlet J Tags: Am J Respir Crit Care Med Source Type: research

Severe adult respiratory distress syndrome from goodpasture syndrome. Survival using extracorporeal membrane oxygenation.
PMID: 25590156 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Balke L, Both M, Arlt A, Rosenberg M, Bewig B Tags: Am J Respir Crit Care Med Source Type: research

An official american thoracic society policy statement: managing conscientious objections in intensive care medicine.
CONCLUSIONS: This American Thoracic Society statement provides guidance for clinicians, hospital administrators, and policymakers to address clinicians' COs in the critical care setting. PMID: 25590155 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Lewis-Newby M, Wicclair M, Pope T, Rushton C, Curlin F, Diekema D, Durrer D, Ehlenbach W, Gibson-Scipio W, Glavan B, Langer RL, Manthous C, Rose C, Scardella A, Shanawani H, Siegel MD, Halpern SD, Truog RD, White DB, ATS Ethics and Conflict of Interest Co Tags: Am J Respir Crit Care Med Source Type: research

Novel Approaches Are Needed to Develop Tomorrow's Antibacterial Therapies.
Abstract Society faces a crisis of rising antibiotic resistance even as the pipeline of new antibiotics has been drying up. Antibiotics are a public trust; every individual's use of antibiotics affects their efficacy for everyone else. As such, responses to the antibiotic crisis must take a societal perspective. The market failure of antibiotics is due to a combination of scientific challenges to discovering and developing new antibiotics, unfavorable economics, and a hostile regulatory environment. Scientific solutions include changing the way we screen for new antibiotics. More transformationally, developing new ...
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Spellberg B, Bartlett J, Wunderink R, Gilbert DN Tags: Am J Respir Crit Care Med Source Type: research

Toward improved diagnosis of early asthma.
PMID: 25590153 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Brehm JM Tags: Am J Respir Crit Care Med Source Type: research

Lung-protective ventilation in acute respiratory distress syndrome. How soon is now?
PMID: 25590152 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Gong MN, Ferguson ND Tags: Am J Respir Crit Care Med Source Type: research

Clearing the air. Smoking and incident asthma in adults.
PMID: 25590151 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Moazed F, Calfee CS Tags: Am J Respir Crit Care Med Source Type: research

Metabolic dysregulation. Driving the obese asthma phenotype in adolescents?
PMID: 25590150 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - January 15, 2015 Category: Respiratory Medicine Authors: Wood LG Tags: Am J Respir Crit Care Med Source Type: research

Chronic Obstructive Pulmonary Disease Is Common in Never-smoking Patients with Primary Sjögren Syndrome.
CONCLUSION: COPD was a common finding in patients with pSS, even among never-smoking patients. An obstructive pattern was the predominant PFT finding in patients with pSS, although a superimposed restrictive lung disease could not be excluded. The results suggest that the disease per se is involved in the development of COPD in pSS. PMID: 25593235 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - January 15, 2015 Category: Rheumatology Authors: Nilsson AM, Diaz S, Theander E, Hesselstrand R, Piitulainen E, Ekberg O, Wollmer P, Mandl T Tags: J Rheumatol Source Type: research

Delayed tracheobronchial rupture after caustic ingestion.
PMID: 25588319 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - January 15, 2015 Category: Respiratory Medicine Authors: Edelmann A, Wald A, Kaisers UX, Struck MF Tags: Clin Respir J Source Type: research

Myocardial dysfunction in severe sepsis and septic shock - no correlation with inflammatory cytokines in real-life clinical setting.
Conclusions: Unlike cardiac biomarkers, none of the measured inflammatory cytokines correlates with systolic or diastolic myocardial dysfunction in severe sepsis or septic shock. PMID: 25591166 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - January 15, 2015 Category: Respiratory Medicine Authors: Landesberg G, Levin PD, Gilon D, Goodman S, Georgieva M, Weissman C, Jaffe AS, Sprung CL, Barak V Tags: Chest Source Type: research

Effects of aerosolized adenosine 5'-triphosphate in smokers and patients with chronic obstructive pulmonary disease.
CONCLUSIONS: Smokers and patients with COPD manifest hypersensitivity to extracellular ATP, which may play a mechanistic role in COPD. PMID: 25590209 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - January 15, 2015 Category: Respiratory Medicine Authors: Basoglu OK, Barnes PJ, Kharitonov SA, Pelleg A Tags: Chest Source Type: research

Nitrite reduction by molybdoenzymes: a new class of nitric oxide-forming nitrite reductases.
Abstract Nitric oxide (NO) is a signalling molecule involved in several physiological processes, in both prokaryotes and eukaryotes, and nitrite is being recognised as an NO source particularly relevant to cell signalling and survival under challenging conditions. The "non-respiratory" nitrite reduction to NO is carried out by "non-dedicated" nitrite reductases, making use of metalloproteins present in cells to carry out other functions, such as several molybdoenzymes (a new class of nitric oxide-forming nitrite reductases). This minireview will highlight the physiological relevance of molybdenum-dependent nitrite-...
Source: Journal of Biological Inorganic Chemistry : JBIC - January 15, 2015 Category: Chemistry Authors: Maia LB, Moura JJ Tags: J Biol Inorg Chem Source Type: research

The associations between ambient air pollution and adult respiratory mortality in 32 major Chinese cities, 2006-2010.
CONCLUSIONS: The elderly respiratory mortality rate in China is positively and statistically significantly associated with air pollution. The effect is largest in northern cities during cold months when coal is burned for heating. PMID: 25601729 [PubMed - as supplied by publisher] (Source: Environmental Research)
Source: Environmental Research - January 15, 2015 Category: Environmental Health Authors: Zhou M, He G, Liu Y, Yin P, Li Y, Kan H, Fan M, Xue A, Fan M Tags: Environ Res Source Type: research

Influences of ACTN3 R577X Variant in Oxygen Uptake are Eliminated by Endurance Training in Healthy Individuals.
CONCLUSION: ACTN3 R577X polymorphism is associated with oxygen uptake. XX individuals have greater aerobic capacity. Endurance training eliminates differences in peak VO2 between XX and RR individuals. These findings suggest a ceiling effect phenomenon, and perhaps, trained individuals may not constitute an adequate population to explain associations between phenotypic variability and gene variations. PMID: 25569611 [PubMed - as supplied by publisher] (Source: International Journal of Sports Physiology and Performance)
Source: International Journal of Sports Physiology and Performance - January 14, 2015 Category: Sports Medicine Tags: Int J Sports Physiol Perform Source Type: research

Reconstruction of esophageal defect by autologous pericardial patch
We report a case of an 11-year-old boy who was referred to our hospital with a history of progressive dysphagia and recurrent respiratory tract infections. The child was evaluated and diagnosed to have a foreign body impaction in the upper part of esophagus causing severe dysphagia with bronchopneumonia. Impacted foreign body was removed from esophagus through right thoracotomy, and esophageal defect was reconstructed primarily by autologous native pericardium. Post-op recovery was uneventful and excellent. (Source: Indian Journal of Thoracic and Cardiovascular Surgery)
Source: Indian Journal of Thoracic and Cardiovascular Surgery - January 14, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Immunology, genetics and microbiota in the COPD pathophysiology: potential scope for patient stratification
Expert Review of Respiratory Medicine, Ahead of Print. (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - January 14, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Breathing exercises: influence on breathing patterns and thoracoabdominal motion in healthy subjects
CONCLUSIONS: The results showed that the breathing exercises investigated in this study produced modifications in the breathing pattern (e.g., increase in tidal volume and decrease in RR) as well as in thoracoabdominal motion (e.g., increase in abdominal contribution during diaphragmatic breathing), among others. CONTEXTUALIZAÇÃO: Os mecanismos envolvidos na execução dos exercícios respiratórios não foram completamente elucidados. OBJETIVOS: Avaliar o impacto de quatro exercícios respiratórios(diafragmático, suspiros inspiratórios, inspiração máxima sustentada e intercostal) sobre o padrão respiratório e o...
Source: Revista Brasileira de Fisioterapia - January 14, 2015 Category: Physiotherapy Source Type: research