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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 13.

Occupational asthma to fish
We report the evaluation of a 31-year-old worker who developed occupational asthma following exposure to sole fish (Yellowfin sole). She had been working in a restaurant's kitchen, cooking different types of products including fish, most often sole. In the last 3 years, this worker had developed erythema and pruritus of the hands and forearms while she was manipulating fishes such as sole. In the month before being assessed at our Centre, she had increasing symptoms of dyspnoea, chest tightness and wheezing when she was exposed to cooking fumes from sole fish. She also reported symptoms suggestive of localised angioed...
Source: Occupational and Environmental Medicine - October 8, 2014 Category: Occupational Health Authors: Boulet, L.-P., Laberge, F. Tags: PostScript Source Type: research

Genitourinary health in a population‐based cohort of males with Duchenne and Becker muscular dystrophies
Discussion: These findings highlight increased awareness of GU health and multidisciplinary care of DBMD patients. © 2014 Wiley Periodicals, Inc. (Source: Muscle and Nerve)
Source: Muscle and Nerve - October 8, 2014 Category: Internal Medicine Authors: Yong Zhu, Paul A. Romitti, Kristin M. Caspers Conway, Sunkyung Kim, Ying Zhang, Michele Yang, Katherine D. Mathews, Tags: Research Article Source Type: research

Stenotrophomonas maltophilia Infection Among Young Children in a Cardiac Intensive Care Unit: A Single Institution Experience
Abstract Stenotrophomonas maltophilia can present as bacteremia, respiratory tract infection, urinary tract infection, soft tissue and wound infections, bone and joint infections, meningitis, and endocarditis especially in immunosuppressed patients and those with underlying medical conditions. The incidence and impact of S. maltophilia in young children with heart disease are poorly defined. A single center retrospective observational study was conducted in infants <180 days of age with positive S. maltophilia cultures over a period of 5 years. The overall incidence for S. maltophilia infection was...
Source: Mammalian Genome - October 8, 2014 Category: Genetics & Stem Cells Source Type: research

Evaluation of a spatially resolved forest fire smoke model for population-based epidemiologic exposure assessment
enderson (Source: Journal of Exposure Science and Environmental Epidemiology)
Source: Journal of Exposure Science and Environmental Epidemiology - October 8, 2014 Category: Epidemiology Authors: Jiayun YaoJeff EyamieSarah B Henderson Tags: forest fire smoke particulate matter respiratory effects cardiovascular effects modeling epidemiology Source Type: research

Inhibitors of PDE4, but Not PDE3, Increase β2-agonist-induced Expression of Anti-inflammatory MKP-1 in Airway Smooth Muscle Cells.
Abstract β2-agonists are principally used in asthma to provide bronchodilation, however they also have anti-inflammatory properties due, in part, to their ability to upregulate mitogen-activated protein kinase phosphatase 1 (MKP-1) in a cAMP-dependent manner. Phosphodiesterases (PDEs) are attractive targets for potentiating the anti-inflammatory response. There are 11 subfamilies of PDE enzymes, among these, inhibition of PDE3 and PDE4 are the main targets for airway smooth muscle (ASM). PDE enzymes are important intracellular regulators that catalyze the breakdown of cAMP and/or cGMP to their inactive forms. Give...
Source: American Journal of Respiratory Cell and Molecular Biology - October 8, 2014 Category: Molecular Biology Authors: Patel BS, Prabhala P, Oliver BG, Ammit AJ Tags: Am J Respir Cell Mol Biol Source Type: research

Regulatory T Cell DNA Methyltransferase Inhibition Accelerates Resolution of Lung Inflammation.
Abstract Acute respiratory distress syndrome (ARDS) is a common and oftentimes fatal inflammatory lung condition without effective targeted therapies. Regulatory T cells (Tregs) resolve lung inflammation, but mechanisms that enhance Tregs to promote resolution of established damage remain unknown. DNA demethylation at the forkhead box protein 3 (Foxp3) locus and other key Treg loci typify the Treg lineage. To test how dynamic DNA demethylation affects lung injury resolution, we administered the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine (DAC) to wild type mice beginning 24 hours after intratracheal lipo...
Source: American Journal of Respiratory Cell and Molecular Biology - October 8, 2014 Category: Molecular Biology Authors: Singer BD, Mock JR, Aggarwal NR, Garibaldi BT, Sidhaye VK, Florez MA, Chau E, Gibbs KW, Mandke P, Tripathi A, Yegnasubramanian S, King LS, D'Alessio FR Tags: Am J Respir Cell Mol Biol Source Type: research

The thermic effect of sugar-free Red Bull: Do the non-caffeine bioactive ingredients in energy drinks play a role?
CONCLUSIONS: sfRB enhanced thermogenesis and marginally shifted RQ to favor carbohydrate oxidation. The stimulatory effects of sfRB on REE are mimicked by water + caffeine, indicating that the auxiliary ingredients do not influence this thermic effect. The metabolic effects of sfRB are primarily due to caffeine alone. PMID: 25294090 [PubMed - as supplied by publisher] (Source: Obesity)
Source: Obesity - October 8, 2014 Category: Eating Disorders and Weight Management Authors: Miles-Chan JL, Charrière N, Grasser EK, Montani JP, Dulloo AG Tags: Obesity (Silver Spring) Source Type: research

Obstructive Sleep Apnea During REM Sleep and Hypertension: Results of the Wisconsin Sleep Cohort.
Conclusions: Our findings indicate that REM OSA is cross-sectionally and longitudinally associated with hypertension. This is clinically relevant since treatment of OSA is often limited to the first half of the sleep period leaving most of REM sleep untreated. PMID: 25295854 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - October 8, 2014 Category: Respiratory Medicine Authors: Mokhlesi B, Finn LA, Hagen EW, Young T, Hla KM, Van Cauter E, Peppard PE Tags: Am J Respir Crit Care Med Source Type: research

Procalcitonin Algorithm in Critically Ill Adults with Undifferentiated Infection or Suspected Sepsis: A Randomized Controlled Trial.
Conclusion: In critically ill adults with undifferentiated infections, a PCT algorithm including 0.1ng/ml cut-off did not achieve 25% the reduction in duration of antibiotic treatment. Clinical trial registration information available at, ID ACTRN12610000809033. PMID: 25295709 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - October 8, 2014 Category: Respiratory Medicine Authors: Shehabi Y, Sterba M, Garrett PM, Rachakonda KS, Stephens D, Harrigan P, Walker A, Bailey MJ, Johnson B, Millis D, Ding G, Peake S, Wong H, Thomas J, Smith K, Forbes L, Hardie M, Micallef S, Fraser JF, the ProGUARD Study Investigators and the ANZICS Clinic Tags: Am J Respir Crit Care Med Source Type: research

Web-based questionnaires to capture acute infections in long-term cohorts : Findings of a feasibility study.
CONCLUSION: Use of WQ in prospective studies seems well possible, as Internet access is frequent among study participants and major technical problems did not occur. We observed high participation during the study period of 6 months and low drop out numbers. Participants of the web-based study were slightly younger and better educated than non-participants, so selection bias is possible and must be kept in mind when discussing generalizability of the results. PMID: 25293887 [PubMed - as supplied by publisher] (Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - October 8, 2014 Category: Global & Universal Authors: Mall S, Akmatov MK, Schultze A, Ahrens W, Obi N, Pessler F, Krause G Tags: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Source Type: research

[The design of a nationwide cohort study in Germany : The pretest studies of the German National Cohort (GNC).]
Abstract The German National Cohort (GNC) is the largest population-based cohort study in Germany. Beginning in 2014, a total of 200,000 women and men aged 20-69 years will be examined in 18 study centers. The aim of the study is to investigate the etiology of chronic diseases in relation to lifestyle, genetic, socioeconomic, and environmental factors and to develop appropriate methods for early diagnosis and prevention of diseases such as cardiovascular and respiratory diseases, cancer, diabetes, neurodegenerative/psychiatric diseases, as well as musculoskeletal and infectious diseases. Pretest studies (phase 1 a...
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - October 8, 2014 Category: Global & Universal Authors: Ahrens W, Greiser H, Linseisen J, Kluttig A, Schipf S, Schmidt B, Günther K Tags: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Source Type: research

Characterization and estimation of human airway deposition of size-resolved particulate-bound trace elements during a recent haze episode in Southeast Asia.
Abstract Toxic elements present in airborne particulate matter (PM) are associated with human health effects; however, their toxic characteristics depend on the source of their origins and their concentrations in ambient air. Twenty four elements (Al, B, Ba, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Se, Sr, Te, Tl, and Zn) in 12 different size fractions of PM ranging from 10 nm to 10 μm were characterized in Singapore during two different atmospheric conditions (smoke haze and non-haze periods) in 2012 for the first time. In addition, their possible sources were identified based on backward ...
Source: Environmental Science and Pollution Research International - October 8, 2014 Category: Environmental Health Authors: Behera SN, Betha R, Huang X, Balasubramanian R Tags: Environ Sci Pollut Res Int Source Type: research

Relationship between haze and acute cardiovascular, cerebrovascular, and respiratory diseases in Beijing.
Abstract Haze is an atmospheric phenomenon in which dry particulate pollutants obscure the sky. Haze has been associated with chronic diseases, but its relationship with acute diseases is less clear. We aimed to determine the association between haze and acute cardiovascular, cerebrovascular, and respiratory diseases, in order to determine the influence of haze on human health. We compared the number of cases of acute cardiovascular, cerebrovascular, and respiratory diseases in Beijing Emergency Center between 2006 and 2013, with haze data from Beijing Observatory. The relationship between the number of hazy days a...
Source: Environmental Science and Pollution Research International - October 8, 2014 Category: Environmental Health Authors: Zhang JJ, Cui MM, Fan D, Zhang DS, Lian HX, Yin ZY, Li J Tags: Environ Sci Pollut Res Int Source Type: research

Parapedobacter indicus sp. nov., isolated from Hexachlorocyclohexane (HCH) contaminated soil.
Abstract Strain RK1(T), a Gram-negative, non-spore forming, rod shaped, non-motile bacterium was isolated from hexachlorocyclohexane (HCH) dumpsite, Lucknow, India. 16S rRNA gene sequence analysis revealed that strain RK1(T) belongs to the family Sphingobacteriaceae and showed highest sequence similarity with Parapedobacter koreensis Jip14(T) (95.7%). The major cellular fatty acids of strain RK1(T) were iso-C15:0, summed feature 3, iso-C17:0 3-OH, summed feature 9, iso-C15:0 3-OH and C16:0. The major respiratory pigment and polyamine of RK1(T) were menaquinone (MK-7) and homospermidine respectively. The main polar ...
Source: International Journal of Systematic and Evolutionary Microbiology - October 8, 2014 Category: Microbiology Authors: Kumar R, Dwivedi V, Nayyar N, Verma H, Singh AK, Rani P, Rao D, Lal R Tags: Int J Syst Evol Microbiol Source Type: research

Mesonia aquimarina sp. nov., a marine bacterium isolated from coastal seawater.
Abstract A Gram-staining-negative, aerobic, yellow-pigmented, non-flagellated, non-gliding, rod-shaped bacterium, designated strain IMCC1021T, was isolated off the coast of the East Sea. Optimal growth of strain IMCC1021T was observed at 25 °C, at pH 7.0-7.5 and in the presence of 3.0-3.5 % (w/v) NaCl. Phylogenetic analysis based on 16S rRNA gene sequences revealed that the strain belonged to the genus Mesonia, showing a close relationship with Mesonia mobilis KMM 6059T (97.4 % similarity) followed by Mesonia phycicola MDSW-25T (96.1 %). DNA-DNA relatedness between strain IMCC1021T and M. mobilis KMM 6059T was 17....
Source: International Journal of Systematic and Evolutionary Microbiology - October 8, 2014 Category: Microbiology Authors: Choi A, Baek K, Lee H, Cho JC Tags: Int J Syst Evol Microbiol Source Type: research

Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: Mitoprotection against Ca(2+)-induced mitochondrial impairment.
Abstract Because mitochondrial oxidative stress and impairment are important mediators of neuronal damage in neurodegenerative diseases and in brain ischemia/reperfusion, in the present study, we evaluated the antioxidant and mitoprotective effect of a new promising neuroprotective molecule, JM-20, in mitochondria and synaptosomes isolated from rat brains. JM-20 inhibited succinate-mediated H2O2 generation in both mitochondria and synaptosomes incubated in depolarized (highK(+)) medium at extremely low micromolar concentration and with identical IC50 values of 0.91μM. JM-20 also repressed glucose-induced H2O2 gene...
Source: Brain Research Bulletin - October 8, 2014 Category: Neurology Authors: Nuñez-Figueredo Y, Pardo-Andreu GL, Ramírez-Sánchez J, Delgado-Hernández R, Ochoa-Rodríguez E, Verdecia-Reyes Y, Naal Z, Muller AP, Portela LV, Souza DO Tags: Brain Res Bull Source Type: research

Obesity and pro-inflammatory mediators are associated with acute kidney injury in patients with A/H1N1 influenza and acute respiratory distress syndrome.
CONCLUSION: High levels of C-peptide and BMI>30kg/m(2) were associated with the development of AKI in ARDS patients due to A/H1N1 infection. These metabolic/obesity indicators, together with the profiles of pro-inflammatory acute phase proteins, may be important links between obesity and poor outcomes in A/H1N1 09 infection. PMID: 25305354 [PubMed - as supplied by publisher] (Source: Experimental and Molecular Pathology)
Source: Experimental and Molecular Pathology - October 8, 2014 Category: Pathology Authors: Cruz-Lagunas A, Jimenez-Alvarez L, Ramírez G, Mendoza-Milla C, García-Sancho MC, Avila-Moreno F, Zamudio P, Urrea F, Ortiz-Quintero B, Campos-Toscuento VL, Morán J, Barrera AA, Martínez-Briseño D, Fernández-Plata R, Sierra-Vargas MP, Muñoz-Perea C, Tags: Exp Mol Pathol Source Type: research

Enhancement of activity of tuberculosis drugs by addition of thioridazine is not reflected by improved therapeutic efficacy
Assessment of the activity of thioridazine towards Mycobacterium tuberculosis (Mtb), in vitro and in vivo as a single drug and in combination with tuberculosis (TB) drugs. (Source: Tuberculosis)
Source: Tuberculosis - October 8, 2014 Category: Respiratory Medicine Authors: Gerjo J. de Knegt, Marian T. ten Kate, Dick van Soolingen, Rob Aarnoutse, Martin J. Boeree, Irma A.J.M. Bakker-Woudenberg, Jurriaan E.M. de Steenwinkel Tags: Drug discovery and resistance Source Type: research

Clinical characteristics and airway inflammation profile of COPD persistent sputum producers
COPD patients with chronic bronchitis include a subgroup with persistent sputum production on most or every day. We hypothesized that COPD patients with persistent sputum production have a different profile of airway inflammation, and more severe clinical characteristics. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - October 8, 2014 Category: Respiratory Medicine Authors: S. Khurana, A. Ravi, J. Sutula, R. Milone, R. Williamson, J. Plumb, J. Vestbo, D. Singh Source Type: research

COPD care programme can reduce readmissions and in-patient bed days
Chronic obstructive pulmonary disease (COPD) is a common disease worldwide with significant morbidity and mortality. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - October 8, 2014 Category: Respiratory Medicine Authors: Fanny W.S. Ko, Jenny C.N. Ngai, Susanna S.S. Ng, Ka-pang Chan, Rita Cheung, Mei-yi Leung, Man-chi Pun, David S.C. Hui Source Type: research

Breathing characteristics of individuals with dentofacial deformity
Conclusion there were no differences regarding the vital capacity and pneumophonic coordination, but the dentofacial deformities group presented lower values of Maximum Phonation Time in the emissions that contain consonant phonemes. (Source: Revista CEFAC)
Source: Revista CEFAC - October 7, 2014 Category: Speech Therapy Source Type: research

'INSPIRED' COPD Outreach ProgramTM: Doing the Right Things Right.
'INSPIRED' COPD Outreach Program<sup>TM</sup>: Doing the Right Things Right. Clin Invest Med. 2014;37(5):E311 Authors: Rocker GM, Verma JY Abstract The well-documented gaps between needed and provided care for patients and families living with chronic obstructive pulmonary disease (COPD) mandate changes to clinical practice. The multifaceted evidence-based INSPIRED COPD Outreach ProgramTM was first implemented in Halifax, Nova Scotia, Canada in 2010 (INSPIRED = Implementing a Novel and Supportive Program of Individualized care for patients and families living with REspiratory Disease) and u...
Source: Clinical and Investigative Medicine - October 7, 2014 Category: Biomedical Science Authors: Rocker GM, Verma JY Tags: Clin Invest Med Source Type: research

New-onset Atrial Fibrillation Post-surgery for Esophageal and Junctional Cancer: Incidence, Management, and Impact on Short- and Long-term Outcomes
Conclusions: New-onset AF is common, linked to age, diabetes, cardiac disease, and neoadjuvant therapy. It is strongly associated with complications, principally respiratory sepsis, and systemic inflammation. For most, it resolves, with no impact on oncologic outcomes. (Source: Annals of Surgery)
Source: Annals of Surgery - October 7, 2014 Category: Surgery Tags: Papers of the 21st Annual ESA Meeting Source Type: research

Pertussis in the Newborn: certainties and uncertainties in 2013
(Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - October 7, 2014 Category: Respiratory Medicine Authors: Gustavo Rocha, Paulo Soares, Henrique Soares, Susana Pissarra, Hercília Guimarães Source Type: research

2-Tier In-Plane Motion Correction and Out-of-Plane Motion Filtering for Contrast-Enhanced Ultrasound
ConclusionThe 2-tier sequential IPMC and adaptive OPMF significantly reduced motion in 3-minute CEUS cines of FLLs, thereby overcoming the challenges of drift and irregular breathing motion in long cines. The 2-tier IPMC strategy provided stable motion correction tolerant of out-of-plane motion throughout the cine by sequentially registering subreference frames that bypassed the motion cycles, thereby overcoming the lack of a nearly stationary reference point in long cines. Out-of-plane motion filter reduced apparent motion by adaptively removing frames imaged off-plane from the automatically selected OPMF reference frame,...
Source: Investigative Radiology - October 7, 2014 Category: Radiology Tags: Original Articles Source Type: research

Clinical signs of dysphagia in infants with acute viral bronchiolitis
Conclusions: Infants with acute viral bronchiolitis displayed swallowing disorders in addition to changes in respiratory rate and measures of oxygen saturation. It is suggested, therefore, that infants displaying these risk factors have a higher probability of dysphagia. (Source: Revista Paulista de Pediatria)
Source: Revista Paulista de Pediatria - October 7, 2014 Category: Pediatrics Source Type: research

Prevalence and severity of wheezing in the first year of life in the city of Santo André, Brazil
Conclusions: In the city of Santo André, approximately half of infants had at least one episode of wheezing in the first year of life, and almost 25% had recurrent wheezing. Wheezing disorders in Santo André have early onset and high morbidity. (Source: Revista Paulista de Pediatria)
Source: Revista Paulista de Pediatria - October 7, 2014 Category: Pediatrics Source Type: research

Detection of porcine reproductive and respiratory syndrome virus in the ovary of gilts culled due to reproductive disturbances
The objective of the present study was to determine the prevalence of PRRS virus antigen by detection in the ovary of gilts culled due to reproductive disturbances. Ovarian tissues were collected from 100 Landrace x Yorkshire crossbred slaughtered gilts in Thailand. PRRS virus antigen in the ovarian tissues were detected by using immunohistochemistry. On average, the gilts were culled at 277 days of age at a body weight of 148 kg. Of these gilts, 75 had attained puberty and 25 had not attained puberty. PRRS virus antigens were detected in the macrophages within the ovary. The histological morphology of macrophages contai...
Source: Comparative Clinical Pathology - October 7, 2014 Category: Pathology Source Type: research

Prevalence and genotypes of the adenovirus infection as well detection of co-infection with bocavirus in Mexican immunosuppressed and non-immunosuppressed children with pneumonia.
CONCLUSIONS: In this 5 year analysis of samples from non-IP and IP hospitalized paediatric patients with a diagnosis of pneumonia, a low incidence of AdV was found. B1 was the most frequent subtype and frequently found in non-IP, and two cases of co-infection AdV/HBoV1 were detected in two non-IP with a influenza-like syndromes. This is the first report of HBoV and AdV co-infection in Mexico. The frequency of AdV and HBoV co-infection was lower than that reported in other populations. PMID: 25185412 [PubMed - indexed for MEDLINE] (Source: Adv Data)
Source: Adv Data - October 7, 2014 Category: Epidemiology Authors: Uribe-Gutiérrez G, Hernández-Santos H, Manjarrez-Zavala ME, Rosete-Olvera DP, Nava-Frías M, Moreno-Espinosa S, Velázquez-Guadarrama N, Gómez R, González-Márquez H, Fierro R, Mejía-Arangure JM, Zavala-Vega S, Hernández-Fernández M, Arellano-Galin Tags: Clin Lab Source Type: research

Smoking aggravates the impaired pulmonary function of officially acknowledged female victims of air pollution of 40 years ago.
In conclusion, exposure to air pollution of 40 years ago and cigarette smoking are associated with reduced pulmonary function. These results highlight the importance of measures aimed at smoking cessation and limiting air pollution. PMID: 25274138 [PubMed - in process] (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - October 7, 2014 Category: Research Authors: Nishinakagawa T, Senjyu H, Tanaka T, Asai M, Kotaki K, Yano Y, Miyamoto N, Yanagita Y, Kozu R, Tabusadani M, Honda S Tags: Tohoku J Exp Med Source Type: research

Oesophageal atresia with tracheo-oesophageal fistula in a preterm neonate in Limbe, Cameroon: case report & brief literature review
Conclusion: A high index of suspicion for Oesophageal atresia/trachea-oesophageal fistula should prevail when faced with a neonate with the triad: respiratory distress during feeds, regurgitation and persistent frothy salivation. The case discusses the diagnostic dilemma and management difficulties in a preterm neonate with the above association in a low income setting. (Source: BioMed Central)
Source: BioMed Central - October 7, 2014 Category: Journals (General) Authors: Leopold N AmindeVeronica N EbenyeWalters T ArreyNoah F TakahGeorge Awungafac Source Type: research

Transnasal insufflation or continuous positive airway pressure (CPAP) in acute stroke. The next step or a new dilemma?
(Source: Sleep and Breathing)
Source: Sleep and Breathing - October 7, 2014 Category: Respiratory Medicine Source Type: research

Using Cluster Analysis to Identify Phenotypes and Validation of Mortality in Men with COPD
Conclusion COPD patient with severe airflow limitation, many symptoms, and a history of frequent severe exacerbations was a novel and distinct clinical phenotype predicting mortality in men with COPD. (Source: Lung)
Source: Lung - October 7, 2014 Category: Respiratory Medicine Source Type: research

Severe alpha-1 antitrypsin deficiency in composite heterozygotes inheriting a new splicing mutation QO Madrid
Conclusion: Finding pathogenic mutations in non-coding regions of the SERPINA1 highlight the importance that regulatory regions might have in the disease. Regulatory regions should be seriously considered in discordant cases with severe AAT deficiency where no coding mutations were found. (Source: Respiratory Research)
Source: Respiratory Research - October 7, 2014 Category: Respiratory Medicine Authors: Beatriz LaraMaria MartínezIgnacio BlancoCristina Hernández-MoroEladio VelascoIlaria FerrarottiFrancisco Rodriguez-FriasLaura PerezIrene VazquezJavier AlonsoManuel PosadaBeatriz Martínez-Delgado Source Type: research

Right Ventricular Global Longitudinal Strain Is an Independent Predictor of Right Ventricular Function: A Multimodality Study of Cardiac Magnetic Resonance Imaging, Real Time Three‐Dimensional Echocardiography and Speckle Tracking Echocardiography
ConclusionRVEF and volumes estimated on RT3DE were closely correlated with CMR measurements. When compared to more traditional markers of RV systolic function and RT3DE, RVGLS produced the highest correlation with CMR RVEF and was a good predictor of RV dysfunction. RV GLS should be considered a complementary modality to RT3DE and CMR in the assessment of RV systolic function. (Source: Echocardiography)
Source: Echocardiography - October 7, 2014 Category: Cardiology Authors: Ken J. Lu, Janet X. C. Chen, Konstantinos Profitis, Leighton G. Kearney, Dimuth DeSilva, Gerard Smith, Michelle Ord, Susan Harberts, Paul Calafiore, Elizabeth Jones, Piyush M. Srivastava Tags: Original Investigation Source Type: research

Hypothyroidism associated with acromegaly and insulin‐resistant diabetes mellitus in a Samoyed
ConclusionsTo the authors' knowledge, this is the first reported case that suggests that GH alterations may have clinical significance in naturally occurring hypothyroidism. Among other factors, hypothyroidism‐induced GH excess should be considered as a possible cause of IR in patients suffering from hypothyroidism and concurrent DM. In such cases, DM may reverse with treatment of hypothyroidism, as was documented in this case. (Source: Australian Veterinary Journal)
Source: Australian Veterinary Journal - October 7, 2014 Category: Veterinary Research Authors: T Johnstone, E Terzo, CT Mooney Tags: CASE REPORT AND CLINICAL REVIEW Source Type: research

What has research over the past two decades revealed about the adverse health effects of recreational cannabis use?
ConclusionsThe epidemiological literature in the past 20 years shows that cannabis use increases the risk of accidents and can produce dependence, and that there are consistent associations between regular cannabis use and poor psychosocial outcomes and mental health in adulthood. (Source: Addiction)
Source: Addiction - October 7, 2014 Category: Addiction Authors: Wayne Hall Tags: Monograph Source Type: research

Structural and functional analysis of the fibronectin binding protein FNE from Streptococcus equi subsp. equi
This article is protected by copyright. All rights reserved. Structured digital abstractGBD and FNE bind by isothermal titration calorimetry (View interaction)GBD 789FI and FNE bind by isothermal titration calorimetry (View interaction)FNE-CT and GBD 789FI bind by isothermal titration calorimetry (View interaction)GBD and FNE-CT bind by isothermal titration calorimetry (View interaction).FNE and GBD 789FI bind by molecular sieving (View interaction)FNE-CT binds to GBD 789FI by pull down (View interaction)FNE and GBD 789FI bind by x ray scattering (View interaction)GBD and FNE physically interact by fluorescence polarizatio...
Source: FEBS Journal - October 7, 2014 Category: Research Authors: Mounira Tiouajni, Dominique Durand, Karine Blondeau, Marc Graille, Agathe Urvoas, Marielle Valerio‐Lepiniec, Asma Guellouz, Magali Aumont‐Nicaise, Philippe Minard, Herman Tilbeurgh Tags: Original Article Source Type: research

Measuring respiratory symptoms of COPD: performance of the EXACT- Respiratory Symptoms Tool (E-RS) in three clinical trials
This study examined the performance of the E-RS in each of 3 controlled trials with common and unique validation variables: one 6-month (N?=?235, US) and two 3-month (N?=?749; N?=?597; international). Subjects completed the E-RS as part of a daily eDiary. Tests of reliability, validity, and responsiveness were conducted in each dataset. Results: In each study, RS-Total score was internally consistent (Cronbach ?) (0.88, 0.92, 0.92) and reproducible (intra-class correlation) in stable patients (2?days apart: 0.91; 7?days apart: 0.71, 0.74). RS-Total scores correlated significantly with the following criterion variables (Spe...
Source: Respiratory Research - October 7, 2014 Category: Respiratory Medicine Authors: Nancy LeidyLindsey MurrayBrigitta MonzLinda NelsenMitchell GoldmanPaul JonesElizabeth DansieSanjay Sethi Source Type: research

Effects of Partial Inhibition of Respiratory Complex I on H2O 2 Production by Isolated Brain Mitochondria in Different Respiratory States.
Abstract The aim of this work was to characterize the effects of partial inhibition of respiratory complex I by rotenone on H2O2 production by isolated rat brain mitochondria in different respiratory states. Flow cytometric analysis of membrane potential in isolated mitochondria indicated that rotenone leads to uniform respiratory inhibition when added to a suspension of mitochondria. When mitochondria were incubated in the presence of a low concentration of rotenone (10 nm) and NADH-linked substrates, oxygen consumption was reduced from 45.9 ± 1.0 to 26.4 ± 2.6 nmol O2 mg(-1) min(-1) and from 7.8 ± 0....
Source: Neurochemical Research - October 7, 2014 Category: Neuroscience Authors: Michelini LG, Benevento CE, Rossato FA, Siqueira-Santos ES, Castilho RF Tags: Neurochem Res Source Type: research

Prick testing with chemicals in the diagnosis of occupational contact urticaria and respiratory diseases
ConclusionPrick tests can be safely used for diagnosing contact urticaria, asthma and rhinitis caused by isocyanates, chloramine‐T, persulfates, and chlorhexidine, but the results should be carefully interpreted and related to clinical symptoms and other diagnostic tests. (Source: Contact Dermatitis)
Source: Contact Dermatitis - October 7, 2014 Category: Dermatology Authors: Eva Helaskoski, Hille Suojalehto, Outi Kuuliala, Kristiina Aalto‐Korte Tags: Original Article Source Type: research