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Respiratory Medicine

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 13.

Impact of clinical decision support on receipt of antibiotic prescriptions for acute bronchitis and upper respiratory tract infection.
CONCLUSIONS: The overall effect of decision support suggests an important role for technology in reducing non-indicated prescriptions. Decision support alone may not be sufficient to eliminate non-indicated prescriptions given secular trends. PMID: 25002458 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 7, 2014 Category: Information Technology Authors: McCullough JM, Zimmerman FJ, Rodriguez HP Tags: J Am Med Inform Assoc Source Type: research

Portopulmonary hypertension and hepatopulmonary syndrome.
Abstract Portopulmonary hypertension (POPH) and hepatopulmonary syndrome (HPS) are two frequent complications of liver disease, with prevalence among liver transplant candidates of 6% and 10%, respectively. Both conditions result from a lack of hepatic clearance of vasoactive substances produced in the splanchnic territory. Subsequently, these substances cause mainly pulmonary vascular remodeling and some degree of vasoconstriction in POPH with resulting elevated pulmonary pressure and right ventricular dysfunction. In HPS the vasoactive mediators cause intrapulmonary shunts with hypoxemia. Medical treatment is dis...
Source: World Journal of Gastroenterology : WJG - July 7, 2014 Category: Gastroenterology Authors: Aldenkortt F, Aldenkortt M, Caviezel L, Waeber JL, Weber A, Schiffer E Tags: World J Gastroenterol Source Type: research

Successful In Utero Intervention for Bilateral Renal Agenesis.
CONCLUSION:: Serial amnioinfusion appears to have mitigated the severe pulmonary compromise that has, in the past, led to the death of newborns with bilateral renal agenesis. PMID: 25004316 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - July 7, 2014 Category: OBGYN Authors: Bienstock JL, Birsner ML, Coleman F, Hueppchen NA Tags: Obstet Gynecol Source Type: research

Babesiosis in Pregnancy.
CONCLUSION:: Diagnosis of babesiosis in pregnancy requires a high index of suspicion to ensure early treatment and optimal pregnancy outcomes. PMID: 25004307 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - July 7, 2014 Category: OBGYN Authors: Luckett R, Rodriguez W, Katz D Tags: Obstet Gynecol Source Type: research

Depression Drug Treatment Outcomes in Pregnancy and the Postpartum Period: A Systematic Review and Meta-analysis.
CONCLUSION:: Evidence about the comparative benefits and harms of pharmacologic treatment of depression in pregnant and postpartum women was largely inadequate to allow informed decisions about treatment. Considering the prevalence of depression, filling this gap is essential. PMID: 25004304 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - July 7, 2014 Category: OBGYN Authors: McDonagh MS, Matthews A, Phillipi C, Romm J, Peterson K, Thakurta S, Guise JM Tags: Obstet Gynecol Source Type: research

Macitentan for the treatment of pulmonary arterial hypertension.
Abstract Macitentan is a novel dual endothelin receptor antagonist recently approved for the treatment of symptomatic pulmonary arterial hypertension (PAH). Compared to other endothelin receptor antagonists, in vitro and in vivo studies have demonstrated that macitentan has improved tissue targeting, a longer duration of action and an improved safety profile. Macitentan is available as a once daily oral medication and has been well tolerated in clinical trials. The recently published Study with an Endothelin Receptor Antagonist in PAH to Improve cliNical Outcomes (SERAPHIN), which was the first event-driven trial e...
Source: Respiratory Care - July 6, 2014 Category: Respiratory Medicine Authors: DuBrock HM, Channick RN Tags: Expert Rev Respir Med Source Type: research

Spatial-temporal excess mortality patterns of the 1918-1919 influenza pandemic in Spain
Conclusions: A substantial fraction of the variability in excess mortality rates across Spanish provinces remained unexplained, which suggests that other unidentified factors such as comorbidities, climate and background immunity may have affected the 1918-19 pandemic mortality rates. Further archeo-epidemiological research should concentrate on identifying settings with combined availability of local historical mortality records and information on the prevalence of underlying risk factors, or patient-level clinical data, to further clarify the drivers of 1918 pandemic influenza mortality. (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - July 5, 2014 Category: Infectious Diseases Authors: Gerardo ChowellAnton ErkorekaCécile ViboudBeatriz Echeverri-Dávila Source Type: research

Predicting treatment failure in patients with community acquired pneumonia: a case-control study
Conclusions: There was a good correlation of IL-6 levels and CAP failure and IL-6 & PCT with late CAP failure. Pleural effusion and multilobar involvement were simple clinical predictors of early and late failure, respectively.Trial registration: IRB Register: 2009/5451. (Source: Respiratory Research)
Source: Respiratory Research - July 5, 2014 Category: Respiratory Medicine Authors: Ignacio Martin-LoechesXavier VallesRosario MenendezOriol SibilaBeatriz MontullCatia CillonizAntonio ArtigasAntoni Torres Source Type: research

Influenza A infection enhances antigen‐induced airway inflammation and hyper‐responsiveness in young but not aged mice
ConclusionWith increased age in a mouse model, viral infection prior to antigen sensitization affects the airway and systemic allergic response differently. These differences may reflect distinct phenotypic features of allergic inflammation in older patients with asthmaThis article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - July 5, 2014 Category: Allergy & Immunology Authors: Janette M. Birmingham, Virginia L. Gillespie, Kamal Srivastava, Xiu‐Min Li, Paula J. Busse Tags: Original Article‐Experimental Models of Allergic Disease Source Type: research

Low birth weight and environmental tobacco smoke increases the risk of wheezing in adolescents: a retrospective cohort study
Conclusions: ETS and LBW each has been related to increasing public health risk for respiratory symptoms among adolescents. Furthermore, LBW may aggravate the risk among those exposed to ETS. LBW, ETS and associated respiratory impairments may deserve special attention as part of a comprehensive environmental health risk assessment directed toward prevention and intervention. (Source: BMC Public Health - Latest articles)
Source: BMC Public Health - Latest articles - July 5, 2014 Category: Consumer Health News Authors: Meng-Hung LinJames CaffreyYu-Sheng LinPau-Chung ChenChing-Chun LinWen-Chao HoTrong-Neng WuRuey-Shiung Lin Source Type: research

Antibiotic treatment following a dog bite in an immunocompromized patient in order to prevent Capnocytophaga canimorsus infection: a case report
Conclusion: Severe Capnocytophaga canimorsus sepsis may be complicated by life-threatening nosocomial infection in immunocompromized patients. The prophylactic application of antibiotics after a dog bite should be considered in high-risk individuals with immune deficiency in order to prevent both Capnocytophyga canimorsus sepsis and serious nosocomial complications. (Source: BMC Research Notes)
Source: BMC Research Notes - July 5, 2014 Category: Research Authors: Ondrej HlochDana MokraJan MasopustJan HasaJiri Charvat Source Type: research

Amlodipine poisoning revisited: Acidosis, acute kidney injury and acute respiratory distress syndrome
We report the case of an 18-year-old girl presenting with shock following ingestion of 85 mg of amlodipine and 850 mg of atenolol with suicidal intent. Subsequently, the patient developed severe metabolic acidosis, acute kidney injury, and acute respiratory distress syndrome, which were managed conservatively. The patient ultimately made a full recovery. Given the popularity of amlodipine and atenolol as antihypertensive drugs in this part of the world, it is likely that more such cases will be encountered in the future. Physicians should be aware of the severe complications that can develop with amlodipine overdose. (Sour...
Source: Indian Journal of Critical Care Medicine - July 5, 2014 Category: Intensive Care Authors: Kushal NahaJ SuryanarayanaRiffat Abdul AzizBarkur Ananthakrishna Shastry Source Type: research

Anesthetic management of patients with Joubert syndrome: a retrospective analysis of a single‐institutional case series
ConclusionAlpha‐2 agonist based anesthetic technique appears to be most suitable for sedation during MRI study in patients with JS with respect to adverse events and outcome. (Source: Pediatric Anesthesia)
Source: Pediatric Anesthesia - July 5, 2014 Category: Anesthesiology Authors: Kamath Sriganesh, Byrappa Vinay, Sritam Jena, Venkataramaiah Sudhir, Jitender Saini, Ganne S. Umamaheswara Rao Tags: Original Article Source Type: research

Rapid Response Team Activations Within 24 Hours of Admission From the Emergency Department: An Innovative Approach for Performance Improvement / Las Activaciones del Equipo de Respuesta Rápida en las Primeras 24 Horas del Ingreso desde el Servicio de Urgencias: Una Aproximación Novedosa para la Mejora del Rendimiento
ConclusionsThe review of RRT activations within 24 hours of admission from the ED significantly supplemented the typical ad hoc referral system for peer review of cases, highlighting cases that likely would not have received attention within the ED. This novel and unique case review process revealed opportunities for education and performance improvement. This and other systematic approaches to case detection may be useful adjuncts to traditional case referrals for review. Resumen ObjetivosLos programas de mejora del rendimiento (MR) en Medicina de Urgencias y Emergencias (MUE) han evolucionado mas allá de las revisione...
Source: Academic Emergency Medicine - July 5, 2014 Category: Emergency Medicine Authors: Paris B. Lovett, Richard J. Massone, Michael N. Holmes, Ronald V. Hall, Bernard L. Lopez Tags: Original Contribution Source Type: research

Central regulation of heart rate and the appearance of Respiratory Sinus Arrhythmia: new insights from mathematical modeling.
Abstract A minimal model for the neural control of heart rate (HR) has been developed with the aim of better understanding respiratory sinus arrhythmia (RSA) - a modulation of HR at the frequency of breathing. This model consists of two differential equations and is integrated into a previously-published model of gas exchange. The heart period is assumed to be affected primarily by the parasympathetic signal, with the sympathetic signal taken as a parameter in the model. We include the baroreflex, mechanical stretch-receptor feedback from the lungs, and central modulation of the cardiac vagal tone by the respirator...
Source: Mathematical Biosciences - July 5, 2014 Category: Statistics Authors: Ben-Tal A, Shamailov SS, Paton JF Tags: Math Biosci Source Type: research

Enforced expression of miR-125b attenuates LPS-induced acute lung injury.
Abstract The acute respiratory distress syndrome (ARDS), a severe form of acute lung injury (ALI) in humans, is a leading cause of morbidity and mortality in critically ill patients. Despite decades of research, few therapeutic strategies for clinical ARDS have emerged. Recent evidence implicated a potential role of miR-125b in development of ALI. Here we evaluated the miR-125b-based strategy in treatment of ARDS using the murine model of lipopolysaccharide (LPS)-induced ALI. We found that up-regulation of miR-125b expression maintained the body weight and survival of ALI mice, and significantly reduced LPS-induced...
Source: Immunology Letters - July 5, 2014 Category: Allergy & Immunology Authors: Guo Z, Gu Y, Wang C, Zhang J, Shan S, Gu X, Wang K, Han Y, Ren T Tags: Immunol Lett Source Type: research

The association between age and the development of respiratory syncytial virus neutralising antibody responses following natural infection in infants.
Abstract To determine the age at which infants mount significant neutralising antibody responses to both natural RSV infection and live vaccines that mimic natural infection, RSV-specific neutralising antibodies in the acute and convalescent phase sera of infants with RSV infection were assayed. Age-specific incidence estimates for hospitalisation with severe RSV disease were determined and compared to age-specific neutralising antibody response patterns. Disease incidence peaked at between 2 and 3.9 months of life. Following natural infection, relative to the mean acute phase antibody titre, the mean convalescent ...
Source: Vaccine - July 5, 2014 Category: Allergy & Immunology Authors: Sande CJ, Cane PA, Nokes DJ Tags: Vaccine Source Type: research

Anesthetic management of patients with Joubert syndrome: a retrospective analysis of a single-institutional case series.
CONCLUSION: Alpha-2 agonist based anesthetic technique appears to be most suitable for sedation during MRI study in patients with JS with respect to adverse events and outcome. PMID: 25040301 [PubMed - as supplied by publisher] (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - July 5, 2014 Category: Anesthesiology Authors: Sriganesh K, Vinay B, Jena S, Sudhir V, Saini J, Umamaheswara Rao GS Tags: Paediatr Anaesth Source Type: research

Active case finding: community health workers' activity related to tuberculosis control in a large city, brazil
This study analyzed the Community Health Workers' activity in active case finding in Ribeirão Preto-SP. Cross sectional study, conducted in 2009-2010, with the use of a structured form, which was applied to 105 Community Health Workers and research of secondary data. Indicators were created based on the variable means that used the Likert scale for the answers, being dissatisfactory (scores 1 and 2), regular (3) and satisfactory (4 and 5). Deficiencies in the activity of the Community Workers in the active case finding were identified (mean=3.0), in the discussion with the community about the tuberculosis (mean=1.5) and i...
Source: Texto e Contexto - Enfermagem - July 4, 2014 Category: Global & Universal Source Type: research

Idiopathic pulmonary fibrosis and coronary artery disease.
Abstract Idiopathic pulmonary fibrosis (IPF) is defined as a chronic fibrosing interstitial disease of unknown cause, limited to the lungs, and associated with the histopathologic and/or radiologic pattern of usual interstitial pneumonia (UIP); it generally progresses into respiratory failure and death. Although progression of the disease is the most common cause of death, there are increasing reports of its association with other pathologies has been reported: e.g., IPF patients seem more susceptible to cardiovascular diseases. Therefore, other pathologies might also influence the natural course. In this paper, we...
Source: Respiratory Care - July 4, 2014 Category: Respiratory Medicine Authors: Cicchitto G, Musella V, Acitorio M, Capuano N, Fiorenzano G, Owen CA, Polverino M, Polverino F Tags: Multidiscip Respir Med Source Type: research

[Viewpoint] Health security in 2014: building on preparedness knowledge for emerging health threats
Ideas, information, and microbes are shared worldwide more easily than ever before. New infections, such as the novel influenza A H7N9 or Middle East respiratory syndrome coronavirus, pay little heed to political boundaries as they spread; nature pays little heed to destruction wrought by increasingly frequent natural disasters. Hospital-acquired infections are hard to prevent and contain, because the bacteria are developing resistance to the therapeutic advances of the 20th century. Indeed, threats come in ever-complicated combinations: a combined earthquake, tsunami, and radiation disaster; blackouts in skyscrapers that ...
Source: LANCET - July 4, 2014 Category: Journals (General) Authors: Ali S Khan, Nicole Lurie Tags: Viewpoint Source Type: research

[Comment] Improving health in the USA: progress and challenges
The health of Americans continues to improve. Life expectancy at birth, 78·7 years (76·2 years for men and 81·0 years for women), has never been higher. Age-adjusted death rates for the four leading causes of death—heart disease, cancer, chronic lower respiratory diseases, and stroke—are all falling. Immunisation rates for young children are high, racial and ethnic disparities in childhood vaccinations have largely been eliminated, and most vaccine-preventable diseases of childhood are now at historically low levels. (Source: LANCET)
Source: LANCET - July 4, 2014 Category: Journals (General) Authors: Harold W Jaffe, Thomas R Frieden Tags: Comment Source Type: research

Falciparum malaria as an emerging cause of Fever in adults living in Gabon, central Africa.
Abstract Following the observed increase of malaria prevalence among older children in Gabon, a descriptive observational study was carried out in 2012 to determine the prevalence of malaria in adults presenting with fever in two health centres of Libreville, the capital city of Gabon. Thick- and thin-blood smears for malaria diagnosis were performed in febrile individuals aged more than 15 years old. Age, use of bed nets, previous antimalarial drug treatment, clinical symptoms, chest radiography results, and available haemoglobin data were also recorded. Among the 304 patients screened, the global malaria frequenc...
Source: Biomed Res - July 4, 2014 Category: Research Authors: Bouyou-Akotet MK, Offouga CL, Mawili-Mboumba DP, Essola L, Madoungou B, Kombila M Tags: Biomed Res Int Source Type: research

Primary immunodeficiency diagnosed at autopsy: a case report
Conclusion: Use of immunohistochemistry on histological sections of tissues derived from autopsy is a useful adjunct for post mortem diagnosis of DiGeorge syndrome. (Source: BMC Research Notes)
Source: BMC Research Notes - July 4, 2014 Category: Research Authors: Edwin WalongEmily RogenaDavid Sabai Source Type: research

European respiratory monographs: community-acquired pneumonia
Book detailsChalmers JD, Pletz MW, Aliberti S (Eds): Community-Acquired Pneumonia. European Respiratory Monographs. Sheffield: European Respiratory Society; 2014, ISBN 978-1-849-84049-1. (Source: Critical Care)
Source: Critical Care - July 4, 2014 Category: Intensive Care Authors: Michael Niederman Source Type: research

Computerized Diagnosis of Respiratory Disorders. SVM Based Classification of VAR Model Parameters of Respiratory Sounds.
Conclusions: The proposed method is promising, nevertheless, it should be improved such that other mathematical models, additional features, and/or other classifiers are to be experimented in future studies. PMID: 24993284 [PubMed - as supplied by publisher] (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - July 4, 2014 Category: Information Technology Authors: Sen I, Saraclar M, Kahya YP Tags: Methods Inf Med Source Type: research

Simulation of Range Imaging-based Estimation of Respiratory Lung Motion. Influence of Noise, Signal Dimensionality and Sampling Patterns.
Conclusions: Our results show the potential of multidimensional breathing signals derived from range images for the model-based estimation of respiratory motion in radiation therapy. PMID: 24993030 [PubMed - as supplied by publisher] (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - July 4, 2014 Category: Information Technology Authors: Wilms M, Werner R, Blendowski M, Ortmüller J, Handels H Tags: Methods Inf Med Source Type: research

Acrolein induced both pulmonary inflammation and the death of lung epithelial cells.
Abstract Acrolein, a compound found in cigarette smoke, is a major risk factor for respiratory diseases. Previous research determined that both acrolein and cigarette smoke produced reactive oxygen species (ROS). As many types of pulmonary injuries are associated with inflammation, this study sought to ascertain the extent to which exposure to acrolein advanced inflammatory state in the lungs. Our results showed that intranasal exposure of mice to acrolein increased CD11c(+)F4/80(high) macrophages in the lungs and increased ROS formation via induction of NF-κB signaling. Treatment with acrolein activated macrophag...
Source: Toxicology Letters - July 4, 2014 Category: Toxicology Authors: Sun Y, Ito S, Nishio N, Tanaka Y, Chen N, Isobe KI Tags: Toxicol Lett Source Type: research

Airway cell involvement in intermittent hypoxia-induced airway inflammation.
CONCLUSIONS: These data suggest a specific inflammatory response of airway cells to IH, independently of systemic events. PMID: 24993984 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - July 4, 2014 Category: Sleep Medicine Authors: Philippe C, Boussadia Y, Prulière-Escabasse V, Papon JF, Clérici C, Isabey D, Coste A, Escudier E, d'Ortho MP Tags: Sleep Breath Source Type: research

[Mechanical circulatory support in pediatrics. Experience at the Hospital de Pediatría Dr. Juan P. Garrahan. Argentina.]
CONCLUSIONS: The mechanical circulatory support in our institution is a safe and standard procedure. We have been using it in a small number of cases with a similar survival to that reported internationally. This complex procedure is widely justified because it allows for the recovery of more than half of the patients who otherwise would have died. PMID: 25001058 [PubMed - as supplied by publisher] (Source: Archivos de Cardiologia de Mexico)
Source: Archivos de Cardiologia de Mexico - July 4, 2014 Category: Cardiology Authors: Moreno GE, Magliola R, Pilán ML, Althabe M, Balestrini M, Lenz AM, Krysnki M, Rodríguez R, Salgado G, Martin A, Cardoso H, Ruffa P, Cornelis CJ, Barreta J, García Delucis P Tags: Arch Cardiol Mex Source Type: research

Synthesis and antiviral activity of new phenylimidazopyridines and N-benzylidenequinolinamines derived by molecular simplification of phenylimidazo[4,5-g]quinolines.
Abstract Continuing our program of research concerning the antiviral activity of a wide series of new angular and linear azolo bicyclic and tricyclic derivatives, now we have simplified and modified the 4-chloro-2-(4-nitrophenyl)-3H-imidazo[4,5-g]quinoline 1, which previously resulted the most active derivative, through either the elimination of the central ring or the opening of the imidazole ring, obtaining various imidazopyridines and N-benzylidenequinolinamines respectively. Title compounds were tested in cell-based assays for cytotoxicity and antiviral activity against representatives of two DNA virus families...
Source: European Journal of Medicinal Chemistry - July 4, 2014 Category: Chemistry Authors: Loddo R, Briguglio I, Corona P, Piras S, Loriga M, Paglietti G, Carta A, Sanna G, Giliberti G, Ibba C, Farci P, La Colla P Tags: Eur J Med Chem Source Type: research

Predictive values of antibodies against in patients with cystic fibrosis one year after early eradication treatment
Patient dependent parameters to predict the long-term success of early eradication treatment of Pseudomonas aeruginosa have not yet been defined. For this purpose we assessed serum antibodies against P. aeruginosa in CF patients after early eradication treatment. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - July 4, 2014 Category: Respiratory Medicine Authors: Matthias Kappler, Felicitas Nagel, Maria Feilcke, Gabriele Heilig, Ann-Christin Grimmelt, Ingo Pawlita, Armin Irnstetter, Jenna Hildebrandt, Helen Burmester, Caroline Kröner, Matthias Griese Source Type: research

Comprehensive multiplexed protein quantitation delineates eosinophilic and neutrophilic experimental asthma
Conclusion: Our data suggest that the commercial markers we are currently relying on to diagnose asthma subtypes are not giving us comprehensive or specific enough information. The analysed protein profiles allowed to discriminate the two models and may add useful information for characterization of different asthma phenotypes. (Source: BMC Pulmonary Medicine - Latest articles)
Source: BMC Pulmonary Medicine - Latest articles - July 3, 2014 Category: Respiratory Medicine Authors: Maria BergquistSofia JonassonJosephine HjobergGöran HedenstiernaJörg Hanrieder Source Type: research

The Epidemiology and Resistance Mechanisms of Acinetobacter baumannii Isolates from the Respiratory Department ICU of a Hospital in China
Microbial Drug Resistance , Vol. 0, No. 0. (Source: Microbial Drug Resistance)
Source: Microbial Drug Resistance - July 3, 2014 Category: Microbiology Tags: article Source Type: research

Laryngeal mask airway versus endotracheal tube for percutaneous dilatational tracheostomy in critically ill adult patients.
CONCLUSIONS: Evidence on the safety of LMA for PDT is too limited to allow conclusions to be drawn on its efficacy or safety compared with ETT. Although the LMA procedure is shorter because of optimal visual conditions, its effect on especially late complications has not been investigated sufficiently. Studies focusing on late complications and relevant patient-related outcomes are necessary for definitive conclusions on safety issues related to this procedure. PMID: 24979320 [PubMed - in process] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - July 3, 2014 Category: Journals (General) Authors: Strametz R, Pachler C, Kramer JF, Byhahn C, Siebenhofer A, Weberschock T Tags: Cochrane Database Syst Rev Source Type: research

The Cohort for Childhood Origin of Asthma and allergic diseases (COCOA) study: design, rationale and methods
DiscussionThe COCOA study will improve our understanding of how individual genetic or environmental risk factors influence susceptibility to allergic disease and how these variables interact to shape the phenotype of allergic diseases. (Source: BMC Pulmonary Medicine - Latest articles)
Source: BMC Pulmonary Medicine - Latest articles - July 3, 2014 Category: Respiratory Medicine Authors: Hyeon-Jong YangSo-Yeon LeeDong In SuhYoun ShinByoung-Ju KimJu-Hee SeoHyoung ChangKyung KimKangmo AhnYee-Jin ShinKyung-Sook LeeCheol LeeSe-Young OhHo KimJong-Han LeemHwan KimEun-Jin KimJoo-Shil LeeSoo-Jong Hong Source Type: research

COPD Phenotypes in a Lung Cancer Screening Population
ConclusionCombining LDCT with PFT and a comprehensive questionnaire allows subgroup classification of COPD phenotypes in a high risk population and may lead to earlier intervention and an improved framework for future studies. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - July 3, 2014 Category: Respiratory Medicine Authors: Arzu Balkan, Yonca Bulut, Carl R. Fuhrman, Stephen N. Fisher, David O. Wilson, Joel L Weissfeld, Frank C. Sciurba Tags: Original Article Source Type: research

Laryngopharyngeal symptoms in patients with asthma; A cross‐sectional controlled study
ConclusionLaryngopharyngeal reflux disease is more prevalent and more severe in patients with asthma vs. controls. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - July 3, 2014 Category: Respiratory Medicine Authors: Abdul Latif Hamdan, Hussein Jaffal, Rachel Btaiche, Zaahir A. Turfe, Ibrahim Bawab, Nadim Kanj Tags: Original Article Source Type: research

The clinical significance of hematologic parameters in patients with sarcoidosis
ConclusionsNLR may be a biomarker with good sensitivity that is easily detected in serum. It can be proposed in clinical practice to identify a patient's prognosis. However, large prospective studies are required to further demonstrate the prognostic significance of these values. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - July 3, 2014 Category: Respiratory Medicine Authors: Nigar Dirican, Ceyda Anar, Sule Kaya, Haci Ahmet Bircan, Huseyin Halilcolar, Munire Cakir Tags: Original Article Source Type: research

Critical role of RIG‐I‐like receptors in inflammation in chronic obstructive pulmonary disease
ConclusionOur results suggested that MDA‐5, but not RIG‐I, may plays a critical role in airway inflammation in COPD. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - July 3, 2014 Category: Respiratory Medicine Authors: Qiurui Zhang, Huanying Wan, Shaoguang Huang, Yan Zhang, Yanchun Wang, Xiaokui Guo, Ping He, Min Zhou Tags: Original Article Source Type: research

Ectopic pancreas in a giant mediastinal cyst
We present a case of an ectopic pancreas located in a giant mediastinal cyst in an 18‐year old male. He presented with symptoms of dyspnea due to external compression of the cyst on the left main bronchus. Complete surgical resection was performed through median sternotomy, with relief of the bronchial compression postoperatively. Literature review showed twenty previously reported cases. These masses were usually large (>10cm), almost exclusively located in the anterior mediastinum, predominately cystic in nature, and generally benign. Surgical resection was performed in all reported cases with a favorable prognosis....
Source: The Clinical Respiratory Journal - July 3, 2014 Category: Respiratory Medicine Authors: Wilson W. Li, Wim Jan Boven, Roy R. Jurhill, Peter I. Bonta, Jouke T. Annema, Bas A. Mol Tags: Case Report Source Type: research