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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 14.

Increased level of protection of respiratory tract and kidney by combining different infectious bronchitis virus vaccines against challenge with nephropathogenic Brazilian genotype subcluster 4 strains.
Abstract Genotyping of 7 IBV strains isolated in Brazil showed that all belonged to the common Brazilian genotype and that these strains were closest to the subcluster of strain IBV/Brazil/2007/USP-19. Pathotyping of four selected Brazilian strains showed that they all caused a considerable level of ciliostasis in the trachea but at a somewhat lower level than did M41 and Brazilian strains 50/96, 57/96, 62/96 and 64/96 representing 4 different serotypes that had been reported earlier. In contrast to the M41 challenge strain, all Brazilian isolates replicated in kidney tissue in a high percentage of non-vaccinated c...
Source: Avian Pathology - July 16, 2015 Category: Pathology Authors: De Wit JJ, Brandao P, Torres CA, Koopman R, Villarreal LY Tags: Avian Pathol Source Type: research

Is COPD associated with increased mortality and morbidity in hospitalized pneumonia? A systematic review and meta‐analysis
Abstract This review aimed to investigate whether chronic obstructive pulmonary disease (COPD) is associated with increased mortality and morbidity in patients hospitalized with community‐acquired pneumonia (CAP). EMBASE, PubMed and Web of Science were searched for cohort studies and case–control studies investigating the impact of COPD on CAP. The primary outcome was all‐cause mortality, and secondary outcomes included length of hospital stay, intensive care unit (ICU) admission and need for mechanical ventilation. Methodological quality was assessed using the Newcastle–Ottawa Scale. The Mantel–Haenszel method a...
Source: Respirology - July 15, 2015 Category: Respiratory Medicine Authors: Hong‐Li Jiang, Hong‐Xuan Chen, Wei Liu, Tao Fan, Guan‐Jian Liu, Bing Mao Tags: Review Source Type: research

Retinopathy of prematurity and associated factors in Lagos, Nigeria.
CONCLUSION: The frequency of ROP and treatable ROP was high; it is therefore recommended that routine care of preterm infants should include screening for ROP and that affordable treatment facilities should be provided in public hospitals. PMID: 26166039 [PubMed - as supplied by publisher] (Source: Paediatrics and international child health)
Source: Paediatrics and international child health - July 15, 2015 Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research

Negligible respiratory irritation and inflammation potency of pigmentary TiO2 in mice
Inhalation Toxicology, Ahead of Print. (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - July 15, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Neuromuscular electrical stimulation as an adjunct to endurance and resistance training during pulmonary rehabilitation in stable chronic obstructive pulmonary disease
Expert Review of Respiratory Medicine, Ahead of Print. (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - July 15, 2015 Category: Respiratory Medicine Tags: article Source Type: research

The need to differentiate between adults and children when treating severe asthma
Expert Review of Respiratory Medicine, Ahead of Print. (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - July 15, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Leptin Is Oversecreted by Respiratory Syncytial Virus-Infected Bronchial Epithelial Cells and Regulates Th2 and Th17 Cell Differentiation
Conclusion: Leptin was oversecreted by RSV-infected hBECs, which promoted Th17 subset differentiation but suppressed Th2 subset differentiation possibly via regulating ERK1/2 phosphorylation.Int Arch Allergy Immunol 2015;167:65-71 (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - July 15, 2015 Category: Allergy & Immunology Source Type: research

Integrated Allergy and Asthma Prevention and Care: Report of the MeDALL/AIRWAYS ICPs Meeting at the Ministry of Health and Care Services, Oslo, Norway
Allergic diseases and asthma are increasing in prevalence globally. They can start early in life and many persist. It is important to prevent, detect and control these diseases early on and throughout life, so as to promote active and healthy ageing. The translational activities of MeDALL (Mechanisms of the Development of Allergy; EU FP7) are of great importance and include the deployment of successful allergy programmes. The Finnish Allergy Plan is a prototype for the prevention and control of severe allergic diseases. It has been considered for deployment to Norway by the Ministry of Health and Care Services in the frame...
Source: International Archives of Allergy and Immunology - July 15, 2015 Category: Allergy & Immunology Source Type: research

Combined Surgical and Interventional Approaches for Treating Patients with Congenital Heart Disease
ConclusionsThe CCBSI represents a safe and effective treatment for selected patients with complex CHD. It will be helpful in minimizing patients’ surgical trauma and in shortening or avoiding the use of cardiopulmonary bypass. (Source: Journal of Cardiac Surgery)
Source: Journal of Cardiac Surgery - July 15, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Vladimiro L. Vida, Alvise Guariento, Fabio Zucchetta, Massimo A. Padalino, Ornella Milanesi, Nicola Maschietto, Giovanni Stellin Tags: Original Article Source Type: research

Design of a mouse restraint for synchrotron-based computed tomography imaging
High-resolution computed tomography (CT) imaging of a live animal within a lead-lined synchrotron light hutch presents several unique challenges. In order to confirm that the animal is under a stable plane of anaesthesia, several physiological parameters (e.g. heart rate, arterial oxygen saturation, core body temperature and respiratory rate) must be remotely monitored from outside the imaging hutch. In addition, to properly scan the thoracic region using CT, the animal needs to be held in a vertical position perpendicular to the fixed angle of the X-ray beam and free to rotate 180°–360°. A new X-ray transparent mouse ...
Source: Journal of Synchrotron Radiation - July 15, 2015 Category: Physics Authors: Gagnon, K.B.Caine, S.Samadi, N.Martinson, M.van der Loop, M.Alcorn, J.Chapman, L.D.Belev, G.Nichol, H. Tags: three-dimensional printing computer-aided design remote physiological monitoring anaesthesia X-ray imaging short communications Source Type: research

Animal models for SARS and MERS coronaviruses
Publication date: August 2015 Source:Current Opinion in Virology, Volume 13 Author(s): Lisa M Gretebeck , Kanta Subbarao The emergence of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) and Middle East Respiratory Syndrome coronavirus (MERS-CoV), two strains of animal coronaviruses that crossed the species barrier to infect and cause severe respiratory infections in humans within the last 12 years, have taught us that coronaviruses represent a global threat that does not recognize international borders. We can expect to see other novel coronaviruses emerge in the future. An ideal animal model should reflect the ...
Source: Current Opinion in Virology - July 15, 2015 Category: Virology Source Type: research

Regulation of leucocyte homeostasis in the circulation
The functions of blood cells extend well beyond the immune functions of leucocytes or the respiratory and hemostatic functions of erythrocytes and platelets. Seen as a whole, the bloodstream is in charge of nurturing and protecting all organs by carrying a mixture of cell populations in transit from one organ to another. To optimize these functions, evolution has provided blood and the vascular system that carries it with various mechanisms that ensure the appropriate influx and egress of cells into and from the circulation where and when needed. How this homeostatic control of blood is achieved has been the object of stud...
Source: Cardiovascular Research - July 15, 2015 Category: Cardiology Authors: Scheiermann, C., Frenette, P. S., Hidalgo, A. Tags: INVITED SPOTLIGHT REVIEWS Source Type: research

Natural history of COPD: Focusing on change in FEV1
Abstract The natural history of chronic obstructive pulmonary disease (COPD) is usually described with a focus on change in forced expiratory volume in 1 s (FEV1) over time as this allows for exploration of risk factors for an accelerated decline—and thus of developing COPD. From epidemiological studies we have recognized important risk factors such as smoking, exposure to biomass and occupational exposures, but we have also learnt about features such as chronic bronchitis, airway hyper‐responsiveness and asthma that seem to accelerate decline in FEV1 independent of exposures. In addition we are gradually beginning t...
Source: Respirology - July 15, 2015 Category: Respiratory Medicine Authors: Jørgen Vestbo, Peter Lange Tags: Invited Review Series: Unravelling the Many Faces of COPD to Optimize Its Care and Outcomes Source Type: research

Continuous mucociliary transport by primary human airway epithelial cells in vitro
In this study, we have characterized a novel method that allows human airway epithelial cells to differentiate into a mucociliary epithelium that transports mucus in a continuous circular track. The mucociliary transport device allows the measurement and manipulation of all features of mucociliary transport in a controlled in vitro system. In this initial study, the effect of ciliary beat frequency and mucus concentration on the speed of mucociliary transport was investigated. (Source: AJP: Lung Cellular and Molecular Physiology)
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Authors: Sears, P. R., Yin, W.-N., Ostrowski, L. E. Tags: INNOVATIVE METHODOLOGY Source Type: research

Automated acquisition and analysis of airway surface liquid height by confocal microscopy
The airway surface liquid (ASL) is a thin-liquid layer that lines the luminal side of airway epithelia. ASL contains many molecules that are involved in primary innate defense in the lung. Measurement of ASL height on primary airway cultures by confocal microscopy is a powerful tool that has enabled researchers to study ASL physiology and pharmacology. Previously, ASL image acquisition and analysis were performed manually. However, this process is time and labor intensive. To increase the throughput, we have developed an automatic ASL measurement technique that combines a fully automated confocal microscope with novel auto...
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Authors: Choi, H.-C., Kim, C. S. K., Tarran, R. Tags: INNOVATIVE METHODOLOGY Source Type: research

Time course of cigarette smoke-induced changes of systemic inflammation and muscle structure
It has become more evident that long-term cigarette smoking (LTCS) has an important extrapulmonary toxicity. The aim of the study was to investigate the time-dependent effects of cigarette smoke exposure on exercise capacity, markers of systemic inflammation, and skeletal muscle structure. c57bl/6j-mice were either exposed to mainstream cigarette smoke for 6 h/day, 5 days/wk [smoke-exposed (SE) group] or assigned to the control, unexposed group (Con group). SE group mice were exposed for 8, 16, 24, and 32 wk to smoke and unexposed Con mice were used as age-matched controls. Exercise capacity was investigated by spiroergome...
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Authors: Kruger, K., Dischereit, G., Seimetz, M., Wilhelm, J., Weissmann, N., Mooren, F. C. Tags: CALL FOR PAPERS Source Type: research

IL-6 trans-signaling increases expression of airways disease genes in airway smooth muscle
In this study, human airway smooth muscle (HASM) cells were treated with IL-6 (classical) or IL-6+sIL6R (trans-signaling) for 24 h and gene expression was measured by RNAseq. Intracellular signaling and transcription factor activation were assessed by Western blotting and luciferase assay, respectively. The functional effect of IL-6 trans-signaling was determined by proliferation assay. IL-6 trans-signaling had no effect on phosphoinositide-3 kinase and Erk MAP kinase pathways in HASM cells. Both classical and IL-6 trans-signaling in HASM involves activation of Stat3. However, the kinetics of Stat3 phosphorylation by IL-6 ...
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Authors: Robinson, M. B., Deshpande, D. A., Chou, J., Cui, W., Smith, S., Langefeld, C., Hastie, A. T., Bleecker, E. R., Hawkins, G. A. Tags: CALL FOR PAPERS Source Type: research

Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-{delta}/Akt pathway and increasing GR expression
Corticosteroid insensitivity, which is induced by cigarette smoke extract (CSE), is a significant barrier when treating chronic obstructive pulmonary disease (COPD). Erythromycin (EM) has been shown to have an anti-inflammatory role in some chronic airway inflammatory diseases, particularly diffuse panbronchiolitis and cystic fibrosis. Here, we explored whether the combination therapy of EM and dexamethasone (Dex) reverses corticosteroid insensitivity and investigated the molecular mechanism by which this occurs. We demonstrated that the combination of EM and Dex restored corticosteroid sensitivity in peripheral blood mono...
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Authors: Sun, X.-J., Li, Z.-H., Zhang, Y., Zhou, G., Zhang, J.-Q., Deng, J.-M., Bai, J., Liu, G.-N., Li, M.-H., MacNee, W., Zhong, X.-N., He, Z.-Y. Tags: CALL FOR PAPERS Source Type: research

14-3-3 isoforms bind directly exon B of the 5'-UTR of human surfactant protein A2 mRNA
In conclusion, the 14-3-3 protein family affects differential regulation of SP-A1 and SP-A2 by binding directly to SP-A2 5'-UTR mRNA. (Source: AJP: Lung Cellular and Molecular Physiology)
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Authors: Noutsios, G. T., Ghattas, P., Bennett, S., Floros, J. Tags: CALL FOR PAPERS Source Type: research

Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice
Suppression of type 17 immunity by type I interferon (IFN) during influenza A infection has been shown to enhance susceptibility to secondary bacterial pneumonia. Although this mechanism has been described in coinfection with gram-positive bacteria, it is unclear whether similar mechanisms may impair lung defense against gram-negative infections. Furthermore, precise delineation of the duration of type I IFN-associated susceptibility to bacterial infection remains underexplored. Therefore, we investigated the effects of preceding influenza A virus infection on subsequent challenge with the gram-negative bacteria Escherichi...
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Authors: Lee, B., Robinson, K. M., McHugh, K. J., Scheller, E. V., Mandalapu, S., Chen, C., Di, Y. P., Clay, M. E., Enelow, R. I., Dubin, P. J., Alcorn, J. F. Tags: ARTICLES Source Type: research

Defective parasympathetic innervation is associated with airway branching abnormalities in experimental CDH
Developmental mechanisms leading to lung hypoplasia in congenital diaphragmatic hernia (CDH) remain poorly defined. Pulmonary innervation is defective in the human disease and in the rodent models of CDH. We hypothesize that defective parasympathetic innervation may contribute to airway branching abnormalities and, therefore, lung hypoplasia, during lung development in CDH. The murine nitrofen model of CDH was utilized to study the effect of the cholinergic agonist carbachol on embryonic day 11.5 (E11.5) lung explant cultures. Airway branching and contractions were quantified. In a subset of experiments, verapamil was adde...
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Authors: Rhodes, J., Saxena, D., Zhang, G., Gittes, G. K., Potoka, D. A. Tags: ARTICLES Source Type: research

Endothelial disruptive proinflammatory effects of nicotine and e-cigarette vapor exposures
The increased use of inhaled nicotine via e-cigarettes has unknown risks to lung health. Having previously shown that cigarette smoke (CS) extract disrupts the lung microvasculature barrier function by endothelial cell activation and cytoskeletal rearrangement, we investigated the contribution of nicotine in CS or e-cigarettes (e-Cig) to lung endothelial injury. Primary lung microvascular endothelial cells were exposed to nicotine, e-Cig solution, or condensed e-Cig vapor (1–20 mM nicotine) or to nicotine-free CS extract or e-Cig solutions. Compared with nicotine-containing extract, nicotine free-CS extract (10&ndash...
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Authors: Schweitzer, K. S., Chen, S. X., Law, S., Van Demark, M., Poirier, C., Justice, M. J., Hubbard, W. C., Kim, E. S., Lai, X., Wang, M., Kranz, W. D., Carroll, C. J., Ray, B. D., Bittman, R., Goodpaster, J., Petrache, I. Tags: ARTICLES Source Type: research

Il-17A contributes to maintenance of pulmonary homeostasis in a murine model of cigarette smoke-induced emphysema
Smoking is the main risk factor for the development of the chronic obstructive pulmonary disease (COPD) in Western countries. Recent studies suggest that IL-17A and Th17 cells play a role in the pathogenesis of COPD. We used a murine model of chronic cigarette smoke (CS) exposure to explore the contribution of IL-17A to CS-induced lung damage and loss of pulmonary function. Histology and morphometry showed that IL-17A deficiency spontaneously resulted in a loss of lung structure under basal conditions. Even though inflammatory markers [IL-1β and granulocyte colony-stimulating factor (G-CSF)] were decreased in IL-17A-d...
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Authors: Voss, M., Wolf, L., Kamyschnikow, A., Wonnenberg, B., Honecker, A., Herr, C., Lepper, P. M., Wegmann, M., Menger, M. D., Bals, R., Beisswenger, C. Tags: ARTICLES Source Type: research

Cyclic stretch stimulates mitochondrial reactive oxygen species and Nox4 signaling in pulmonary artery smooth muscle cells
This study was designed to determine whether cyclic stretch induces a persistent pulmonary hypertension of the newborn (PPHN) phenotype of increased NADPH oxidase (Nox) 4 signaling in control pulmonary artery smooth muscle cells (PASMC), and to identify the signal transduction molecules involved. To achieve this, PPHN was induced in lambs by antenatal ligation of the ductus arteriosus at 128 days gestation. After 9 days, lungs and PASMC were isolated from control (twin) and PPHN lambs. Control PASMC were exposed to cyclic stretch at 1 Hz and 15% elongation for 24 h. Stretch-induced Nox4 expression was attenuated by inhibit...
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Authors: Wedgwood, S., Lakshminrusimha, S., Schumacker, P. T., Steinhorn, R. H. Tags: ARTICLES Source Type: research

Corrigendum
(Source: AJP: Lung Cellular and Molecular Physiology)
Source: AJP: Lung Cellular and Molecular Physiology - July 15, 2015 Category: Respiratory Medicine Tags: CORRIGENDA Source Type: research

Postperfusion lung syndrome: Respiratory mechanics, respiratory indices and biomarkers
Shi-Min YuanAnnals of Thoracic Medicine 2015 10(3):151-157Postperfusion lung syndrome is rare but lethal. Secondary inflammatory response was the popularly accepted theory for the underlying etiology. Respiratory index (RI) and arterial oxygen tension/fractional inspired oxygen can be reliable indices for the diagnosis of this syndrome as X-ray appearance is always insignificant at the early stage of the onset. Evaluations of extravascular lung water content and pulmonary compliance are also helpful in the definite diagnosis. Multiorgan failure and triple acid-base disturbances that might develop secondary to postperfusion...
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Shi-Min Yuan Source Type: research

Auscultation of the respiratory system
Malay Sarkar, Irappa Madabhavi, Narasimhalu Niranjan, Megha DograAnnals of Thoracic Medicine 2015 10(3):158-168Auscultation of the lung is an important part of the respiratory examination and is helpful in diagnosing various respiratory disorders. Auscultation assesses airflow through the trachea-bronchial tree. It is important to distinguish normal respiratory sounds from abnormal ones for example crackles, wheezes, and pleural rub in order to make correct diagnosis. It is necessary to understand the underlying pathophysiology of various lung sounds generation for better understanding of disease processes. Bedside teachin...
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Malay SarkarIrappa MadabhaviNarasimhalu NiranjanMegha Dogra Source Type: research

Overweight-mortality paradox and impact of six-minute walk distance in lung transplantation
Conclusion: In lung transplant recipients under lung allocation score (LAS) era, pretransplant BMI and SMWD were independent predictors for mortality after the transplant. The lowest mortality risk was noted in a group of transplant recipients identified as overweight; whereas, being underweight or obese was associated with increased mortality. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Kongkiat ChaikriangkraiHye Yeon JhunEdward A GravissSoma Jyothula Source Type: research

Prevalence and risk factors of asymptomatic bronchiectasis in patients with rheumatoid arthritis at a tertiary care center in Saudi Arabia
Conclusions: Asymptomatic bronchiectasis represents a common complication in moderately active RA patients within the Western Region of Saudi Arabia. Furthermore, several predictors of bronchiectasis development were identified, which can contribute to effective risk stratification in RA patients. Further prospective studies are needed to detect the prognosis of asymptomatic bronchiectasis in RA patients. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Suzan Mansour AttarOmer Saeed AlamoudiAssma Abdullah Aldabbag Source Type: research

Management of malignant pleural effusion by an indwelling pleural catheter: A cost-efficiency analysis
Conclusions: The treatment with IPC was effective, safe, without need of any more procedures and led to improved dyspnea in more than 85% of the patients. The cost is lower in the outpatient group, although complications represent an increased cost in both groups. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Maribel Botana RialIsaura Parente LamelaVirginia Leiro FernándezJosé Abal ArcaManuel Núñez DelgadoCarlos Vilariño VilariñoCristina Ramos HernándezAlberto Fernández-Villar Source Type: research

Incidence of tuberculosis and immunological profile of TB/HIV co-infected patients in Nigeria
Conclusion: There was high incidence of TB in the studied HIV cohort with a deleterious effect on the outcome of ART treatment. There is need for early TB screening and re-screening among all HIV patients. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Baba Maiyaki MusaBabashani MusaHamza MuhammedNashabaru IbrahimAbubakar Garbati Musa Source Type: research

Prevalence of restless legs syndrome and associated risk factors among middle-aged Saudi population
Conclusion: The prevalence of RLS is 8.4%, which is within the range reported by Western studies. However, unlike findings of most studies, RLS significantly affects males more than females. In addition, snoring, asthma, and consanguinity are potential new risk factors for RLS. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Siraj Omar WaliBahaa Abaalkhail Source Type: research

Correlation between pentraxin-3 and endothelial dysfunction in obstructive sleep apnea syndrome
Conclusion: OSAS patients have significantly elevated pentraxin-3 levels and endothelial dysfunction. Furthermore, both pentraxin-3 and endothelial dysfunction were independently associated with severity of OSAS defined by AHI. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Asiye KanbayElif KayaHakan BüyükoglanMehmet Güngör KayaZuhal Özer SimsekNuri TutarRamazan Demir Source Type: research

Saudi experience in the management of pulmonary arterial hypertension; the outcome of PAH therapy with the exclusion of chronic parenteral prostacyclin
Conclusion: Our patients are detected at advanced stage of the disease, and thus the mortality is still unacceptably high. Advanced functional class at presentation and certain disease subgroups are associated with increased mortality. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Majdy IdreesKhalid AlnajashiJasim AbdulhameedAtika KhanEnas BatubaraAbdelmajeed AlotayAmal FayedSaleh AldammasMoaad AlseifHusam AlawwadYahya AbusabaaMashael AlmobradTarek KashourThe Registry Taskforce SAPH Source Type: research

Amyloidosis involving the respiratory system: 5-year's experience of a multi-disciplinary group's activity
Raffaele Scala, Uberto Maccari, Chiara Madioni, Duccio Venezia, Lidia Calogera La MagraAnnals of Thoracic Medicine 2015 10(3):212-216Amyloidosis may involve the respiratory system with different clinical-radiological-functional patterns which are not always easy to be recognized. A good level of knowledge of the disease, an active integration of the pulmonologist within a multidisciplinary setting and a high level of clinical suspicion are necessary for an early diagnosis of respiratory amyloidosis. The aim of this retrospective study was to evaluate the number and the patterns of amyloidosis involving the respiratory syst...
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Raffaele ScalaUberto MaccariChiara MadioniDuccio VeneziaLidia Calogera La Magra Source Type: research

Recurrent intrathoracic solitary fibrous tumor: Remarkable response to radiotherapy
Sezai CubukAnnals of Thoracic Medicine 2015 10(3):217-217 (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Sezai Cubuk Source Type: research

Is fludeoxyglucose-fluorodeoxyglucose-positron emission tomography/computed tomography ( 18 F-FDG-PET/CT) really useless in staging pulmonary carcinoid tumors and in discriminating histological subtypes? Controversial points and future perspectives
Filippo Lococo, Alessandro Stefani, Giorgio TregliaAnnals of Thoracic Medicine 2015 10(3):217-218 (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Filippo LococoAlessandro StefaniGiorgio Treglia Source Type: research

Re-emerging Middle East respiratory syndrome coronavirus: The hibernating bat hypothesis
Hana Fakhoury, Ali HajeerAnnals of Thoracic Medicine 2015 10(3):218-219 (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Hana FakhouryAli Hajeer Source Type: research

Bocavirus viremia
Pathoom Sukkaromdee, Viroj WiwanitkitAnnals of Thoracic Medicine 2015 10(3):219-219 (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Authors: Pathoom SukkaromdeeViroj Wiwanitkit Source Type: research

Factors associated with poor asthma control in the outpatient clinic setting: Erratum
Annals of Thoracic Medicine 2015 10(3):220-220 (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - July 15, 2015 Category: Respiratory Medicine Source Type: research

Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells
Conclusion: Kit contributes to human mast cell adhesion to human airway epithelial cells and HASMCs, but may utilise a previously unidentified adhesion domain that lies outside the SCF binding site. Targeting this adhesion pathway might offer a novel approach for the inhibition of mast cell interactions with structural airway cells, without detrimental effects on Kit signalling in other tissues. (Source: Respiratory Research)
Source: Respiratory Research - July 15, 2015 Category: Respiratory Medicine Authors: Kevin GoughBen MaddisonAarti ShikotraElena MoiseevaWeidong YangShila JarvisPeter Bradding Source Type: research