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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 14.

Diffuse alveolar damage ups death risk in acute respiratory distress syndrome
Among patients with acute respiratory distress syndrome (ARDS), those who are also diagnosed with diffuse alveolar damage (DAD) via an open lung biopsy face nearly twice as high a mortality risk as... (Source: Hospitalist News)
Source: Hospitalist News - June 19, 2016 Category: Hospital Management Source Type: research

Myasthenia gravis in patients with thymoma affects survival rate following extended thymectomy.
Authors: Zhang Z, Cui Y, Jia R, Xue L, Liang H Abstract Thymomas are the most common adult tumors in the anterior mediastinal compartment, and a significant amount of thymomas are complicated by myasthenia gravis (MG). Extended thymectomy (ET) is the primary treatment method for thymomas and is used to completely resect possible ectopic thymus to avoid recurrence. Studies on the effect of MG in thymoma patients following ET are limited. The aim of the present study was to determine whether the presence of MG affects the prognosis of patients with thymoma. The present study consisted of 104 patients with thymoma tha...
Source: Oncology Letters - June 19, 2016 Category: Cancer & Oncology Tags: Oncol Lett Source Type: research

Neonatal and Maternal Temperature Regulation During and After Delivery.
Abstract An important goal of obstetric anesthesia is to provide for the safety and comfort of the mother as well as to optimize physiologic outcomes for the neonate. Markers of neonatal physiologic outcome include cord umbilical artery pH and Apgar scores. Neonatal temperature has often been overlooked by anesthesiologists as an important physiologic outcome measure, but it may be significantly affected by operating room conditions and obstetric anesthesia technique at cesarean delivery. There is a dose-dependent increase in mortality with decreasing body temperature as well as an increased likelihood for more sev...
Source: Anesthesia and Analgesia - June 19, 2016 Category: Anesthesiology Authors: Perlman J, Kjaer K Tags: Anesth Analg Source Type: research

A Qualitative Investigation of the Impact of Asthma and Self-management Strategies among Older Adults.
CONCLUSIONS: Asthma had a distinct impact on elderly adults' quality of life; due to their longstanding history with this condition, many patients had accepted these symptoms as a "new normal." Developing strategies to reorient patients' perceptions of the possibilities for managing their illness will be critical to the success of asthma self-management support programs specific to older adults. PMID: 27315570 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - June 19, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Propofol-remifentanil anesthesia for upper airway endoscopy in spontaneous breathing patients: the ENDOTANIL randomized trial.
CONCLUSIONS: The adjunction of remifentanil to propofol TCI, at a dose that maintain spontaneous breathing, did not improve the conditions for pan endoscopy, but attenuates the hemodynamic response induced by upper airway stimulation. PMID: 27314599 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - June 19, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Using cysteine/cystine to overcome oxidative stress in goat oocytes and embryos cultured in vitro.
In conclusion, cysteine and cystine reduced the oxygen tension caused by H2O2, thereby providing a novel strategy for optimizing in vitro embryonic development systems. PMID: 27315595 [PubMed - as supplied by publisher] (Source: Molecular Medicine Reports)
Source: Molecular Medicine Reports - June 19, 2016 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Recombinant human brain natriuretic peptide attenuates LPS-induced cellular injury in human fetal lung fibroblasts via inhibiting MAPK and NF-κB pathway activation.
Authors: Song Z, Zhao X, Liu M, Jin H, Cui Y, Hou M, Gao Y Abstract Inflammatory responses are vital in lung injury diseases, particularly acute respiratory distress syndrome (ARDS). Recombinant human brain natriuretic peptide (rhBNP) has been shown to exhibit anti‑inflammatory effects in vivo in our previous studies. The present study aimed to investigate the mechanisms underlying the anti‑inflammatory effects of rhBNP on lipopolysaccharide (LPS)-induced human fetal lung fibroblasts (HFL-1). The results showed that LPS induced a significant increase in the leakage of lactate dehydrogenase and the secretion of...
Source: Molecular Medicine Reports - June 19, 2016 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Synergistic effect of ethno medicinal plants against biofilm forming Streptococcus pyogenes isolated from upper respiratory tract infection
The present study is an attempt to determine the synergistic anti-biofilm efficacy of three Indian medicinal plants namely Ocimum tenuiflorum, Plectranthus amboinicus, and Tylophora indica (OPT) against the biofilm forming Streptococcus pyogenes of upper respiratory tract infection. The leaves were collected and subjected to methanol extraction. The combined extract (OPT) was subjected to preliminary phytochemical and GC-MS analysis. About, ten isolates of S. pyogenes were obtained from the throat swabs samples and studied for biofilm forming potential. The strong biofilm forming isolates were subjected to Minimal Inhibito...
Source: International Journal of Phytomedicine - June 19, 2016 Category: Science Authors: MANIMEKALAI KANAGARAJAN Source Type: research

Aetiology of bronchiectasis in adults: A systematic literature review
Abstract While identifying the underlying aetiology is a key part of bronchiectasis management, the prevalence and impact of identifying the aetiologies on clinical management remain unclear. We aimed to determine the etiological spectrum of bronchiectasis, and how often etiological assessment could lead to the changes in patients' management. A comprehensive search was conducted using MEDLINE (via PubMed) and EMBASE for observational studies published before October 2015 reporting aetiologies in adults with bronchiectasis. Of the 8216 citations identified, 56 studies including 8608 adults with bronchiectasis were relevant...
Source: Respirology - June 19, 2016 Category: Respiratory Medicine Authors: Yong‐hua Gao, Wei‐jie Guan, Shao‐xia Liu, Lei Wang, Juan‐juan Cui, Rong‐chang Chen, Guo‐jun Zhang Tags: Systematic Review Source Type: research

Prevalence and management of recurrent respiratory papillomatosis (RRP) in the UK: cross‐sectional study
ConclusionsThe numbers of recurrent respiratory papillomatosis patients and Coblation procedures identified in England from a cross‐sectional survey and Hospital Episode Statistics were in broad agreement. Our study estimated 1.42 recurrent respiratory papillomatosis patients per 100 000 in the general UK population. We also estimated that Coblation procedures accounted for 3% of interventional treatments conducted in the UK recurrent respiratory papillomatosis population. (Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - June 19, 2016 Category: ENT & OMF Authors: A. J. Donne, K. Keltie, H. Cole, A.J. Sims, H. Patrick, S. Powell Tags: Original Article Source Type: research

The LINA Study: Higher Sensitivity of Infant Compared to Maternal Eosinophil/Basophil Progenitors to Indoor Chemical Exposures.
Conclusions. We demonstrate that infant's hematopoietic cells seem to respond with more sensitivity to environmental exposure compared to maternal cells. At least in infants, an activation of these hematopoietic cells by environmental exposure could contribute to an enhanced risk for the development of respiratory outcomes. PMID: 27313631 [PubMed - in process] (Source: Journal of Environmental and Public Health)
Source: Journal of Environmental and Public Health - June 18, 2016 Category: Environmental Health Tags: J Environ Public Health Source Type: research

Predicting Outcomes From Respiratory Distress: Does Another Score Help to Solve the Problem?*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Editorials Source Type: research

Ventilatory Strategies in Patients With Hematologic Malignancies and Acute Respiratory Failure: New Insights, New Questions, What Now?*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Editorials Source Type: research

Using Supervised Machine Learning to Classify Real Alerts and Artifact in Online Multisignal Vital Sign Monitoring Data*
Conclusions: Machine-learning models can discern clinically relevant peripheral oximetry, blood pressure, and respiratory rate alerts from artifacts in an online monitoring dataset (area under the curve > 0.87). (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

The Equilibration of PCO2 in Pigs Is Independent of Lung Injury and Hemodynamics
Conclusions: The transition between PetCO2 equilibria after changes in respiratory rate might not be dependent on moderate lung injury or cardiac output but on the metabolic production or capacity of cO2 stores. Linear relationships previously found for lung-healthy patients and early prediction of PetCO2 equilibration could therefore also be used for the titration of respiratory rate on the PetCO2 for a wider range of pathologies by the physician or an automated ventilation system. (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Online Laboratory Investigations Source Type: research

Sprouty-Related Ena/Vasodilator-Stimulated Phosphoprotein Homology 1-Domain–Containing Protein-2 Critically Regulates Influenza A Virus–Induced Pneumonia
Conclusions: These data support an important function of sprouty-related Ena/vasodilator-stimulated phosphoprotein homology 1-domain–containing protein-2 in controlling influenza virus–induced pneumonia and viral replication. Sprouty-related Ena/vasodilator-stimulated phosphoprotein homology 1-domain–containing protein-2 may be a novel therapeutic target for controlling the immune response against influenza influenza A virus infection. (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Online Laboratory Investigations Source Type: research

Alda-1 Attenuates Lung Ischemia-Reperfusion Injury by Reducing 4-Hydroxy-2-Nonenal in Alveolar Epithelial Cells
Conclusions: Our study indicates that the accumulation of 4-hydroxy-2-nonenal plays an important role in lung ischemia-reperfusion injury. Alda-1 pretreatment can attenuate lung ischemia-reperfusion injury, possibly through the activation of aldehyde dehydrogenase-2, which in turn removes 4-hydroxy-2-nonenal in human pulmonary alveolar epithelial cells. Alda-1 pretreatment has clinical implications to protect lungs during cardiopulmonary bypass. (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Online Laboratory Investigations Source Type: research

Lung Functional and Biologic Responses to Variable Ventilation in Experimental Pulmonary and Extrapulmonary Acute Respiratory Distress Syndrome
Conclusions: Variable ventilation improved lung function in both pulmonary acute respiratory distress syndrome and extrapulmonary acute respiratory distress syndrome. Variable ventilation led to more pronounced beneficial effects in biologic marker expressions in pulmonary acute respiratory distress syndrome compared with extrapulmonary acute respiratory distress syndrome but preserved E-cadherin in lung tissue only in extrapulmonary acute respiratory distress syndrome, thus suggesting lower damage to epithelial cells. (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Online Laboratory Investigations Source Type: research

Serum Amyloid P Contained in Alveolar Fluid From Patients With Acute Respiratory Distress Syndrome Mediates the Inhibition of Monocyte Differentiation into Fibrocyte
Conclusions: The presence of fibrocytes in the lung during acute respiratory distress syndrome could result in a balance between higher ability of monocytes to differentiate into fibrocytes and the inhibitory effect of the alveolar environment, mainly dependent on serum amyloid P. (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Online Laboratory Investigations Source Type: research

Changes in Whole-Body Oxygen Consumption and Skeletal Muscle Mitochondria During Linezolid-Induced Lactic Acidosis
Conclusions: Linezolid-induced lactic acidosis is associated with diminished global oxygen consumption and extraction. These changes reflect selective inhibition of mitochondrial protein synthesis (probably translation) with secondary mitonuclear imbalance. One novel aspect of linezolid toxicity that needs to be confirmed is blunting of reactive mitochondrial biogenesis and unfolded protein response. (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Online Case Reports Source Type: research

Intracardiac Right-to-Left Shunt Impeding Liberation From Veno-Venous Extracorporeal Membrane Oxygenation: Two Case Studies
Conclusions: Veno-venous extracorporeal membrane oxygenation return flow generates a high-pressure jet that has potential to exert focal pressure upon the intra-atrial septum. In patients with potential for interatrial flow, this may lead to a right-to-left shunt, which becomes physiologically apparent only when sweep gas flow is ceased. (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Online Case Reports Source Type: research

Age, PaO2/FIO2, and Plateau Pressure Score: A Proposal for a Simple Outcome Score in Patients With the Acute Respiratory Distress Syndrome*
Conclusions: A simple 9-point score based on the values of age, PaO2/FIO2 ratio, and plateau pressure calculated at 24 hours on protective ventilation after acute respiratory distress syndrome diagnosis could be used in real time for rating prognosis of acute respiratory distress syndrome patients with high probability. (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Impact of Initial Ventilatory Strategy in Hematological Patients With Acute Respiratory Failure: A Systematic Review and Meta-Analysis*
Conclusions: Noninvasive mechanical ventilation is associated with a lower risk of death in hematological patients with respiratory failure. Noninvasive mechanical ventilation failure may worsen the prognosis, mainly in less severe patients. (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Review Article Source Type: research

Can we measure ‘Sensationalisim’ and ‘Spin’?
Two papers address these terms, more often seen in newsstands but unusual in a clinical epidemiology journal, of: ‘sensationalism’ and ‘spin’. Hoffman et al report on the development and validation of a method for automatically quantifying sensationalism and comparing this to relevance and scientific quality of news reports. The authors conclude that automated methods can evaluate news records faster, cheaper, and possibly better than humans. From a sample of 163,433 news records mentioning the Severe Acute Respiratory Syndrome (SARS) and H1N1 pandemics, the computer model agreed with human assessment of sensation...
Source: Journal of Clinical Epidemiology - June 18, 2016 Category: Epidemiology Authors: Peter Tugwell, J. André Knottnerus Tags: Editorial Source Type: research

Notes from the Field: Strongyloidiasis at a Long-Term-Care Facility for the Developmentally Disabled - Arizona, 2015.
Abstract Strongyloides stercoralis is an intestinal nematode endemic in the tropics and subtropics. Infection is usually acquired through skin contact with contaminated soil, or less commonly, from person to person through fecal contamination of the immediate environment. Infections are often asymptomatic, but can result in a pruritic rash, respiratory symptoms (e.g., cough or wheeze), and gastrointestinal symptoms (e.g., diarrhea and vomiting). Immunosuppressed persons can develop strongyloides hyperinfection syndrome, which can be fatal (1). In June 2015, the Pinal County Public Health Services District in Arizon...
Source: MMWR Morb Mortal Wkl... - June 18, 2016 Category: Epidemiology Authors: Jones JM, Hill C, Briggs G, Gray E, Handali S, McAuliffe I, Montgomery S, Komatsu K, Adams L Tags: MMWR Morb Mortal Wkly Rep Source Type: research

Surgical Method, Postoperative Complications, and Gastrointestinal Motility of Thoraco-Laparoscopy 3-Field Esophagectomy in Treatment of Esophageal Cancer.
CONCLUSIONS Thoraco-laparoscopic esophagectomy was technically feasible and safe; it was associated with lower incidence of certain postoperative complications and had less effect on postoperative gastrointestinal motility. Skilled technique and cooperation could further shorten the operation time and might lead to better patient outcomes. PMID: 27310399 [PubMed - as supplied by publisher] (Source: Medical Science Monitor)
Source: Medical Science Monitor - June 18, 2016 Category: Research Tags: Med Sci Monit Source Type: research

Effects of tiotropium + olodaterol versus tiotropium or placebo by COPD disease severity and previous treatment history in the OTEMTO® studies
As lung function declines rapidly in the early stages of chronic obstructive pulmonary disease (COPD), the effects of bronchodilators in patients with moderate disease and those who have not previously receive... (Source: Respiratory Research)
Source: Respiratory Research - June 18, 2016 Category: Respiratory Medicine Authors: Dave Singh, Mina Gaga, Olaf Schmidt, Leif Bjermer, Lars Grönke, Florian Voß and Gary T. Ferguson Source Type: research

Lung stress, strain, and energy load: engineering concepts to understand the mechanism of ventilator-induced lung injury (VILI)
It was recently shown that acute respiratory distress syndrome (ARDS) mortality has not been reduced in over 15 years and remains ~40 %, even with protective low tidal volume (LVt) ventilation. Thus, there is ... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - June 18, 2016 Category: Surgery Authors: Gary F. Nieman, Joshua Satalin, Penny Andrews, Nader M. Habashi and Louis A. Gatto Source Type: research

Aerosol concentration and particle size distributions in underground excavations of hard coal mine.
Authors: Skubacz K, Wojtecki Ł, Urban P Abstract Deposition of aerosols in the respiratory system depends inter alia on their size and the respiratory tract deposition is appreciable for nanometer-sized particles. This paper presents the results of measurements of size distributions of aerosols in the range of several nanometers up to about 20 µm in the underground mine excavations of an active hard coal mine. The study included practically all particles of a respirable fraction. The results showed that a high concentration of fine and ultrafine aerosols occurs in key underground workplaces especially during mini...
Source: International Journal of Occupational Safety and Ergonomics - June 18, 2016 Category: Occupational Health Tags: Int J Occup Saf Ergon Source Type: research

Associations between brain white matter integrity and disease severity in obstructive sleep apnea
This study examines associations between an index of tissue integrity, magnetization transfer (MT) ratio values (which show MT between free and proton pools associated with tissue membranes and macromolecules), and disease severity (apnea‐hypopnea index [AHI]) in OSA subjects. We collected whole‐brain MT imaging data from 19 newly diagnosed, treatment‐naïve OSA subjects (50.4 ± 8.6 years of age, 13 males, AHI 39.7 ± 24.3 events/hr], using a 3.0‐Tesla MRI scanner. With these data, whole‐brain MT ratio maps were calculated, normalized to common space, smoothed, and correlated with AHI scores by using partial cor...
Source: Journal of Neuroscience Research - June 18, 2016 Category: Neuroscience Authors: Sudhakar Tummala, Bhaswati Roy, Bumhee Park, Daniel W. Kang, Mary A. Woo, Ronald M. Harper, Rajesh Kumar Tags: Research Article Source Type: research

Continuous interscalene brachial plexus nerve block prolongs unilateral diaphragmatic dysfunction
Conclusion Over infusion, continuous ISB did not significantly prolong unilateral phrenic paresis and demonstrated a limited pulmonary impact. (Source: Anaesthesia, Critical Care and Pain Medicine)
Source: Anaesthesia, Critical Care and Pain Medicine - June 18, 2016 Category: Anesthesiology Source Type: research

Preface: Cystic Fibrosis in Children and Adults
(Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - June 18, 2016 Category: Respiratory Medicine Authors: T J David Source Type: research

Multiple prevalent fractures in relation to macroscopic bone architecture in patients with cystic fibrosis
The relative risk for bone fractures in patients with cystic fibrosis (CF) and its relationship to macroscopic bone architecture assessed by pQCT and DXA are incompletely defined. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - June 18, 2016 Category: Respiratory Medicine Authors: Mirjam Stahl, Christian Holfelder, Carolin Kneppo, Meinhard Kieser, Christian Kasperk, Eckhard Schoenau, Olaf Sommerburg, Burkhard Tönshoff Tags: Original Article Source Type: research

CF end point commentary
With the development of new, potentially disease-modifying treatments for patients with cystic fibrosis (CF) in recent years, the review article by Stanojevic and Ratjen in this edition of the Journal of Cystic Fibrosis is timely [1]. The authors point out that over the course of time, as more and more effective therapies to treat the pulmonary manifestations of CF have been available, it is increasingly difficult to design, conduct, and interpret studies using the lung-function-based, forced expiratory volume in 1second, (FEV1) as a primary end point in clinical studies. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - June 18, 2016 Category: Respiratory Medicine Authors: Anthony G. Durmowicz Source Type: research

Iron deficiency anemia as a risk factor in childhood asthma
Conclusions Iron deficiency anemia may be considered as an indirect risk factor for childhood asthma also iron deficiency anemia may have a negative effect on spirometry of asthmatic children. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - June 18, 2016 Category: Respiratory Medicine Source Type: research

Clinical presentations and outcome of severe community-acquired pneumonia
Conclusion SCAP occurs more frequently in those with comorbidities. The most frequent isolated causative organism of SCAP is S. pneumoniae, Influenza H1N1 and S. aureus. SCAP is associated with significant mortality, early recognition and prompt treatment may improve outcome. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - June 18, 2016 Category: Respiratory Medicine Source Type: research

Safety and outcome of medical thoracoscopy as diagnostic tool for pleural and pulmonary diseases
Conclusion Medical thoracoscopy is safe and effective for the diagnosis of benign and malignant pleural disease and pulmonary nodules. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - June 18, 2016 Category: Respiratory Medicine Source Type: research

Sildenafil citrate therapy for secondary pulmonary arterial hypertension due to chronic obstructive lung disease
Conclusion Sildenafil improves exercise capacity, and hemodynamic in patients with symptomatic pulmonary arterial hypertension. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - June 18, 2016 Category: Respiratory Medicine Source Type: research

A mucoactive drug carbocisteine ameliorates steroid resistance in rat COPD model
Publication date: Available online 18 June 2016 Source:Pulmonary Pharmacology & Therapeutics Author(s): Yun Song, Ping Yu, Juan-Juan Lu, Hao-Zhong Lu, Liang Zhu, Zhi-Hua Yu, Hong-Zhuan Chen, Yong-Yao Cui Steroid insensitivity has been commonly found in chronic obstructive pulmonary disease (COPD) patients, which is mediated by the reduction of histone deacetylase (HDAC) 2. Here we aimed to establish a steroid resistant model on experimental COPD rats and evaluate the effect of carbocisteine (S-CMC), a mucoactive drug. Exposure to cigarette smoke (CS) caused marked pathological features of COPD which are i...
Source: Pulmonary Pharmacology and Therapeutics - June 18, 2016 Category: Respiratory Medicine Source Type: research

Activation of cannabinoid CB1 receptors suppresses the ROS-induced hypersensitivity of rat vagal lung C-fiber afferents
Conclusions Our results suggest that activation of CB1 receptors may suppress the ROS-mediated VLCF hypersensitivity through a mechanism that is at least partly distinct from the function of TRPA1 and P2X receptors. (Source: Pulmonary Pharmacology and Therapeutics)
Source: Pulmonary Pharmacology and Therapeutics - June 18, 2016 Category: Respiratory Medicine Source Type: research

A critical postnatal period of heightened vulnerability to lipopolysaccharide
Publication date: Available online 18 June 2016 Source:Respiratory Physiology & Neurobiology Author(s): Kyle S. Rourke, Catherine A. Mayer, Peter M. MacFarlane Evidence of respiratory abnormalities and vulnerability to infection during a critical period of development have been implicated in Sudden Infant Death Syndrome (SIDS). Here we investigated whether the acute hypoxic ventilatory response (HVR) exhibits a heightened vulnerability to the endotoxin lipopolysaccharide (LPS) during a critical period of development. The acute HVR was measured 2hrs after an i.p. injection of saline or LPS (0.1mg/kg) at various...
Source: Respiratory Physiology and Neurobiology - June 18, 2016 Category: Respiratory Medicine Source Type: research

Hydroxyethyl starch versus saline for resuscitation of patients in intensive care: long-term outcomes and cost-effectiveness analysis of a cohort from CHEST
Publication date: Available online 17 June 2016 Source:The Lancet Respiratory Medicine Author(s): Colman Taylor, Kelly Thompson, Simon Finfer, Alisa Higgins, Stephen Jan, Qiang Li, Bette Liu, John Myburgh Background Hydroxyethyl starch for fluid resuscitation in critically ill patients is not associated with improved short-term patient-centred outcomes compared with crystalloid fluid solutions. However, its effect on longer term health economic outcomes has not been reported. Methods We did a prespecified cost-effectiveness analysis of a cohort of patients from New South Wales enrolled in the Crystalloid versus ...
Source: The Lancet Respiratory Medicine - June 18, 2016 Category: Respiratory Medicine Source Type: research

The cost of shock resuscitation treatment decisions
Publication date: Available online 17 June 2016 Source:The Lancet Respiratory Medicine Author(s): Michael R Pinsky (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - June 18, 2016 Category: Respiratory Medicine Source Type: research