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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 14.

IFN-{gamma}-mediated reduction of large-conductance, Ca2+-activated, voltage-dependent K+ (BK) channel activity in airway epithelial cells leads to mucociliary dysfunction
Effective mucociliary clearance (MCC) depends in part on adequate airway surface liquid (ASL) volume to maintain an appropriate periciliary fluid height that allows normal ciliary activity. Apically expressed large-conductance, Ca2+-activated, and voltage-dependent K+ (BK) channels provide an electrochemical gradient for Cl– secretion and thus play an important role for adequate airway hydration. Here we show that IFN- decreases ATP-mediated apical BK activation in normal human airway epithelial cells cultured at the air-liquid interface. IFN- decreased mRNA levels of KCNMA1 but did not affect total protein levels. B...
Source: AJP: Lung Cellular and Molecular Physiology - March 1, 2014 Category: Respiratory Medicine Authors: Manzanares, D., Srinivasan, M., Salathe, S. T., Ivonnet, P., Baumlin, N., Dennis, J. S., Conner, G. E., Salathe, M. Tags: ARTICLES Source Type: research

Computed Tomography and Cross‐Sectional Anatomy of the Thorax of the Live Bottlenose Dolphin (Tursiops truncatus)
ABSTRACT Pulmonary disease is one of the leading causes of cetacean morbidity and mortality in the wild and in managed collections. The purpose of this study was to present the computed tomographic (CT) appearance of the thorax of the live bottlenose dolphin (Tursiops truncatus) out‐of‐water and to describe the technical and logistical parameters involved in CT image acquisition in this species. Six thoracic CT evaluations of four conscious adult bottlenose dolphins were performed between April 2007 and May 2012. Animals were trained to slide out of the water onto foam pads and were transported in covered trucks to a h...
Source: The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology - March 1, 2014 Category: Molecular Biology Authors: Marina Ivančić, Mauricio Solano, Cynthia R. Smith Tags: Full Length Article Source Type: research

Antibiotics for acute bronchitis.
CONCLUSIONS: There is limited evidence to support the use of antibiotics in acute bronchitis. Antibiotics may have a modest beneficial effect in some patients such as frail, elderly people with multimorbidity who may not have been included in trials to date. However, the magnitude of this benefit needs to be considered in the broader context of potential side effects, medicalisation for a self-limiting condition, increased resistance to respiratory pathogens and cost of antibiotic treatment. PMID: 24585130 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - March 1, 2014 Category: Journals (General) Authors: Smith SM, Fahey T, Smucny J, Becker LA Tags: Cochrane Database Syst Rev Source Type: research

Impairment of recovery of muscle function by residual rocuronium after re-transfusion of intraoperative salvaged blood.
CONCLUSIONS: In patients who had received a rocuronium infusion during anesthesia, re-transfusion of salvaged blood significantly impaired recovery of neuromuscular function recovery in the PACU, but without significant impairment of respiratory function. PMID: 24571869 [PubMed - in process] (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 1, 2014 Category: Journals (General) Authors: Wang G, Wang J, Zhou H, Zhao X, Wu X Tags: Chin Med J (Engl) Source Type: research

Pro-resolution of inflammation: a potential strategy for treatment of acute lung injury/acute respiratory distress syndrome.
PMID: 24571865 [PubMed - in process] (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 1, 2014 Category: Journals (General) Authors: Shang Y, Yao S Tags: Chin Med J (Engl) Source Type: research

A pilot study of the feasibility and outcomes of yoga for lung cancer survivors.
Conclusions: Yoga was feasible for NSCLC survivors without further compromising breathing with movement. Potential benefits were identified, supporting the need for future clinical trials with larger samples stratified by cancer stage, treatment, and length of survivorship.Implications for Nursing: Nurses and healthcare providers should consider yoga as a mind-body practice to manage stress, improve mood and sleep, and potentially enhance QOL for NSCLC survivors. PMID: 24578076 [PubMed - in process] (Source: Oncology Nursing Forum)
Source: Oncology Nursing Forum - March 1, 2014 Category: Nursing Authors: Fouladbakhsh JM, Davis JE, Yarandi HN Tags: Oncol Nurs Forum Source Type: research

Specialty Pediatric Transport in Primary Care or Urgent Care Settings
Conclusion: Our small cohort demonstrates infrequent application of advanced critical care interventions beyond those provided by the referring primary care office or urgent care centers. This supports the practice of SPCCT teams providing transport services for select critically ill children at primary care offices and urgent care centers, but not as a standard practice for most pediatric patients in these settings. (Source: Air Medical Journal)
Source: Air Medical Journal - March 1, 2014 Category: Emergency Medicine Authors: Crystal N. Joyce, John S. Giuliano, Michael D. Gothard, Hamilton P. Schwartz, Michael T. Bigham Tags: Features Source Type: research

Sudden breathlessness crisis.
Authors: PMID: 24579844 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Tags: Am J Respir Crit Care Med Source Type: research

Giant saphenous vein coronary artery bypass graft aneurysm.
PMID: 24579843 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Authors: Klair IK, Palomino J Tags: Am J Respir Crit Care Med Source Type: research

Reply: club cell protein and chronic obstructive pulmonary disease progression: the unrealized potential of a peripheral lung biomarker.
PMID: 24579842 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Authors: Park HY, Sin DD Tags: Am J Respir Crit Care Med Source Type: research

Club cell protein and chronic obstructive pulmonary disease progression: the unrealized potential of a peripheral lung biomarker.
PMID: 24579841 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Authors: Bernard A Tags: Am J Respir Crit Care Med Source Type: research

Use of Resuscitation-Promoting Factor Proteins Improves the Sensitivity of Culture-based Tuberculosis Testing in Special Samples.
PMID: 24579840 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Authors: Huang W, Qi Y, Diao Y, Yang F, Zha X, Ren C, Huang D, Franken KL, Ottenhoff TH, Wu Q, Shen J Tags: Am J Respir Crit Care Med Source Type: research

Inhaled Granulocyte/Macrophage Colony-Stimulating Factor as Treatment of Pneumonia-associated Acute Respiratory Distress Syndrome.
PMID: 24579839 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Authors: Herold S, Hoegner K, Vadász I, Gessler T, Wilhelm J, Mayer K, Morty RE, Walmrath HD, Seeger W, Lohmeyer J Tags: Am J Respir Crit Care Med Source Type: research

Nebulized liposomal amphotericin B for treating Aspergillus empyema with bronchopleural fistula.
PMID: 24579838 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Authors: Hanada S, Uruga H, Takaya H, Miyamoto A, Morokawa N, Kurosaki A, Kishi K Tags: Am J Respir Crit Care Med Source Type: research

Differences in right ventricular remodeling secondary to pressure overload in patients with pulmonary hypertension.
PMID: 24579837 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Authors: Gomez-Arroyo J, Santos-Martinez LE, Aranda A, Pulido T, Beltran M, Muñoz-Castellanos L, Dominguez-Cano E, Sonnino C, Voelkel NF, Sandoval J Tags: Am J Respir Crit Care Med Source Type: research

Babesiosis.
PMID: 24579836 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Authors: Wiese KM, Mutlu GM Tags: Am J Respir Crit Care Med Source Type: research

Lung clearance index. A potential quantitative tool to assess treatment response in bronchiectasis?
PMID: 24579835 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Authors: Hill AT, Flume PA Tags: Am J Respir Crit Care Med Source Type: research

Bronchiectasis severity: time to score.
PMID: 24579834 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Authors: Restrepo M, Elborn JS Tags: Am J Respir Crit Care Med Source Type: research

From gene variants to novel therapies. Is the prostaglandin e2 pathway in primary graft dysfunction ready for prime time?
PMID: 24579833 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 1, 2014 Category: Respiratory Medicine Authors: Zhang Y Tags: Am J Respir Crit Care Med Source Type: research

March Highlights/Papers by Junior Investigators/NIH News.
Authors: PMID: 24588214 [PubMed - in process] (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - March 1, 2014 Category: Respiratory Medicine Tags: Am J Respir Cell Mol Biol Source Type: research

Is there still a role for hormonal blockade in lymphangioleiomyomatosis?
PMID: 24588213 [PubMed - in process] (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - March 1, 2014 Category: Respiratory Medicine Authors: Baldi BG, Carvalho CR Tags: Am J Respir Cell Mol Biol Source Type: research

Reply: hormonally targeted therapy for women with lymphangioleiomyomatosis.
PMID: 24588212 [PubMed - in process] (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - March 1, 2014 Category: Respiratory Medicine Authors: Yu J Tags: Am J Respir Cell Mol Biol Source Type: research

Viral croup: Diagnosis and a treatment algorithm
Summary Viral croup is a frequent disease in early childhood. Although it is usually self‐limited, it may occasionally become life‐threatening. Mild croup is characterized by the presence of stridor without intercostal retractions, whereas moderate‐to‐severe croup is accompanied by increased work of breathing. A single dose of orally administered dexamethasone (0.15–0.6 mg/kg) is the mainstay of treatment with addition of nebulized epinephrine only in cases of moderate‐to‐severe croup. Nebulized budesonide (2 mg) can be given alternatively to children who do not tolerate oral dexamethasone. Exposure to co...
Source: Pediatric Pulmonology - March 1, 2014 Category: Respiratory Medicine Authors: Argyri Petrocheilou, Kalliopi Tanou, Efthimia Kalampouka, Georgia Malakasioti, Christos Giannios, Athanasios G. Kaditis Tags: State of the Art Source Type: research

A rare case of scimitar syndrome with horseshoe lung.
PMID: 24591675 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - March 1, 2014 Category: Respiratory Medicine Authors: Bhardwaj H, Bhardwaj B Tags: Eur Respir Rev Source Type: research

Successful use of noninvasive ventilation in pregnancy.
PMID: 24591671 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - March 1, 2014 Category: Respiratory Medicine Authors: Allred CC, Matías Esquinas A, Caronia J, Mahdavi R, Mina BA Tags: Eur Respir Rev Source Type: research

Comorbidities in patients with COPD and pulmonary rehabilitation: do they matter?
This article addresses the currently available literature and suggests novel areas for research. PMID: 24591670 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - March 1, 2014 Category: Respiratory Medicine Authors: Franssen FM, Rochester CL Tags: Eur Respir Rev Source Type: research

Pirfenidone: an update on clinical trial data and insights from everyday practice.
Abstract Pirfenidone is an orally active, small molecule that inhibits synthesis of profibrotic and inflammatory mediators. It was approved for the treatment of adults with mild-to-moderate idiopathic pulmonary fibrosis in the European Union based on the results of two pivotal phase III, double-blind, randomised, placebo-controlled clinical trials (CAPACITY) demonstrating efficacy and safety, and supported by two Japanese clinical trials (SP2 and SP3). Currently, there is increasing interest in experience with pirfenidone in patients relating to the real-world setting. Following the publication of the CAPACITY clin...
Source: Respiratory Care - March 1, 2014 Category: Respiratory Medicine Authors: Kreuter M Tags: Eur Respir Rev Source Type: research

Towards personalised therapy for lymphangioleiomyomatosis: lessons from cancer.
Abstract Lymphangioleiomyomatosis (LAM) is a rare cystic, destructive lung disease occurring almost exclusively in females. Bi-allelic inactivating tuberous sclerosis complex (TSC) gene mutations occur in LAM cells, resulting in activation of the mTORC1 pathway. Pivotal clinical trials have demonstrated that inhibition of mTORC1 with sirolimus can induce a partial response of TSC-associated tumours and decrease the rate of lung function decline in females with LAM. Many parallels have been identified between LAM pathogenesis and neoplasia. Here, we highlight three key nodes through which advances in cancer therapy ...
Source: Respiratory Care - March 1, 2014 Category: Respiratory Medicine Authors: El-Chemaly S, Henske EP Tags: Eur Respir Rev Source Type: research

Furosemide Nebulization in Patients With COPD Exacerbation--Reply.
PMID: 24587485 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - March 1, 2014 Category: Respiratory Medicine Authors: Sheikh Motahar Vahedi H, Mahshidfar B, Rabiee H, Saadat S, Shokoohi H, Chardoli M, Rahimi-Movaghar V Tags: Respir Care Source Type: research

Furosemide Nebulization in Patients With COPD Exacerbation.
PMID: 24587484 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - March 1, 2014 Category: Respiratory Medicine Authors: Hadda V, Madan K, Mohan A, Ayub II Tags: Respir Care Source Type: research

Pediatric extubation readiness: faith-based practice or amenable to standardization?
PMID: 24587483 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - March 1, 2014 Category: Respiratory Medicine Authors: Cummings BM, Noviski N Tags: Respir Care Source Type: research