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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 14.

A mitochondria ‐targeted antioxidant can inhibit peroxidase activity of cytochrome c by detachment of the protein from liposomes
This article is protected by copyright. All rights reserved. (Source: FEBS Letters)
Source: FEBS Letters - July 21, 2016 Category: Biochemistry Authors: Alexander M. Firsov, Elena A. Kotova, Viktor N. Orlov, Yuri N. Antonenko, Vladimir P. Skulachev Tags: Research Letter Source Type: research

The multitude of iron –sulfur clusters in respiratory complex I
This article is part of a Special Issue entitled ‘EBEC 2016: 19th European Bioenergetics Conference, Riva del Garda, Italy, July 2–6, 2016’, edited by Prof. Paolo Bernardi. (Source: Biochimica et Biophysica Acta (BBA) Bioenergetics)
Source: Biochimica et Biophysica Acta (BBA) Bioenergetics - July 21, 2016 Category: Biochemistry Source Type: research

Mitochondrial disease-related mutations at the cytochrome b-iron –sulfur protein (ISP) interface: Molecular effects on the large-scale motion of ISP and superoxide generation studied in Rhodobacter capsulatus cytochrome bc1
This article is part of a Special Issue entitled ‘EBEC 2016: 19th European Bioenergetics Conference, Riva del Garda, Italy, July 2–6, 2016’, edited by Prof. Paolo Bernardi. (Source: Biochimica et Biophysica Acta (BBA) Bioenergetics)
Source: Biochimica et Biophysica Acta (BBA) Bioenergetics - July 21, 2016 Category: Biochemistry Source Type: research

Do respiratory limitations affect metabolism of insect larvae before moulting: an empirical test at the individual level [RESEARCH ARTICLE]
Sami M. Kivelä, Philipp Lehmann, and Karl GotthardRecent data suggest that oxygen limitation may induce moulting in larval insects. This oxygen dependent induction of moulting (ODIM) hypothesis stems from the fact that the tracheal respiratory system of insects grows primarily at moults, whereas tissue mass increases massively between moults. This may result in a mismatch between oxygen supply and demand at the end of each larval instar because oxygen demand of growing tissues exceeds the relatively fixed supply capacity of the respiratory system. The ODIM hypothesis predicts that, within larval instars, respiratio...
Source: Journal of Experimental Biology - July 21, 2016 Category: Biology Authors: Kivelä, S. M., Lehmann, P., Gotthard, K. Tags: RESEARCH ARTICLE Source Type: research

Effects of thermal stress on the immune and oxidative stress responses of juvenile sea cucumber Holothuria scabra
< h3 class= " a-plus-plus " > Abstract < /h3 > < p class= " a-plus-plus " > < em class= " a-plus-plus " > Holothuria scabra < /em > is the most valued and cultured tropical sea cucumber, given the great demand of this species for human consumption. However, despite its ecological and economic relevance, little is known regarding its immune responses under thermal stress. Here, the main goal was to study the response of sea cucumbers to temperature stress, assessing sub-organismal alterations and acclimation capacities of juveniles to temperature changes. After changing temperature (1  °C/day) for 6 days, organisms were ...
Source: Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology - July 21, 2016 Category: Physiology Source Type: research

Engineered cationic antimicrobial peptide (eCAP) prevents Pseudomonas aeruginosa biofilm growth on airway epithelial cells
Conclusions While other studies have demonstrated the ability of natural and synthetic antimicrobial peptides to prevent abiotic bacterial biofilm formation, the current studies for the first time demonstrate the effective peptide treatment of a biotic bacterial biofilm in a setting similar to the CF airway, and without negative effects on human airway epithelial cells, thus highlighting the unique potential of this engineered cationic antimicrobial peptide for treatment of human respiratory infections. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - July 21, 2016 Category: Microbiology Authors: Lashua, L. P., Melvin, J. A., Deslouches, B., Pilewski, J. M., Montelaro, R. C., Bomberger, J. M. Tags: Original research Source Type: research

Chapter 6 Low-Density TaqMan ® Array Cards for the Detection of Pathogens
Publication date: 2015 Source:Methods in Microbiology, Volume 42 Author(s): Jude Heaney, Kathryn Rolfe, Nicholas S. Gleadall, Jane S. Greatorex, Martin D. Curran Real-time PCR assays have revolutionised diagnostic microbiology over the past 15 years or more. Adaptations and improvements over that time frame have led to the development of multiplex assays. However, limitations in terms of available fluorophores has meant the number of assays which can be combined has remained in single figures. This latter limitation has led to the focus tending to be on individual pathogens and their detection. This chapter describe...
Source: Methods in Microbiology - July 21, 2016 Category: Microbiology Source Type: research

Oseltamivir resistance in an influenza A (H3N2) virus isolated from an immunocompromised patient during the 2014 ‐2015 influenza season in Alberta, Canada
This article is protected by copyright. All rights reserved. (Source: Influenza and Other Respiratory Viruses)
Source: Influenza and Other Respiratory Viruses - July 21, 2016 Category: Virology Authors: Ahsan Chaudhry, Nathalie Bastien, Yan Li, Allison Scott, Kanti Pabbaraju, Douglas Stewart, Sallene Wong, Steven J. Drews Tags: Short Article Source Type: research

Hospital Surveillance of Influenza Strains: A Concordant Image of Viruses Identified by the Swiss Sentinel System?
ConclusionsAlthough an influenza surveillance system based on the community can predict the type of influenza strains that will be associated with hospitalizations, it fails to estimate the potential virulence of circulating strains. Further, the population characteristics in the community differ from those in hospitalized patients. This suggests that any national influenza surveillance system should include both community and hospital‐based surveys.This article is protected by copyright. All rights reserved. (Source: Influenza and Other Respiratory Viruses)
Source: Influenza and Other Respiratory Viruses - July 21, 2016 Category: Virology Authors: Ana Rita Gon çalves, Anne Iten, Patricia Suter‐Boquete, Manuel Schibler, Laurent Kaiser, Samuel Cordey Tags: Original Article Source Type: research

Epidemiology and Clinical Characteristics of Respiratory Syncytial Virus Infections among Children and Adults in Mexico
ConclusionsThis study confirms that RSV is an important respiratory pathogen in children in Mexico. In addition, a substantial number of cases in adults were also detected highlighting the relevance of this virus in all ages. It is important to identify subjects at high risk of complications who may benefit from current or future preventive interventions.This article is protected by copyright. All rights reserved. (Source: Influenza and Other Respiratory Viruses)
Source: Influenza and Other Respiratory Viruses - July 21, 2016 Category: Virology Authors: Ana E. Gami ño‐Arroyo, Sarbelio Moreno‐Espinosa, Beatriz Llamosas‐Gallardo, Ana A. Ortiz‐Hernández, M. Lourdes Guerrero, Arturo Galindo‐Fraga, Juan F. Galán‐Herrera, Francisco J. Prado‐Galbarro, John H. Beigel, Guillermo M. Ruiz‐Palacio Tags: Original Article Source Type: research

2 ′,5′-Oligoadenylate synthetase 1(OAS1) inhibits PRRSV replication in Marc-145 cells
Publication date: August 2016 Source:Antiviral Research, Volume 132 Author(s): Jinhua Zhao, Na Feng, Zhenhong Li, Peng Wang, Ziyu Qi, Wan Liang, Xiang Zhou, Xuewen Xu, Bang Liu Porcine reproductive and respiratory syndrome virus (PRRSV) is an economically destructive disease for global pig industry. Although its invasion mechanism is clear, the knowledge of pathogen and host interaction is less known. Here, we found that PPRSV infection led to induction of 2′, 5′-oligoadenylate synthetase gene 1(OAS1), an important interferon-stimulated gene. More importantly, ectopic overexpression of OAS1 significantly res...
Source: Antiviral Therapy - July 21, 2016 Category: Virology Source Type: research

Goals of care discussions among hospitalized long ‐term care residents: Predictors and associated outcomes of care
CONCLUSIONIn hospitalized LTC patients, GOC discussions occurred infrequently and appeared to be triggered by illness severity. Orders for advance directives, in‐hospital death, and 1‐year mortality were associated with discussions. Rates of GOC documentation in the discharge summary were poor. This study provides direction for developing education and practice standards to improve GOC discussion rates and their communication back to LTC. Journal of Hospital Medicine 2016. © 2016 Society of Hospital Medicine (Source: Journal of Hospital Medicine)
Source: Journal of Hospital Medicine - July 21, 2016 Category: Hospital Management Authors: Hannah J. Wong, Jamie Wang, Michelle Grinman, Robert C. Wu Tags: Original Research Source Type: research

The outcomes of early aneurysm repair in World Federation of Neurosurgical Societies grade V subarachnoid haemorrhage patients with emphasis on those presenting with a Glasgow Coma Scale score of 3
Publication date: Available online 19 July 2016 Source:Journal of Clinical Neuroscience Author(s): Joji Inamasu, Shunsuke Nakae, Tatsuo Ohmi, Hirotaka Kogame, Yushi Kawazoe, Tadashi Kumai, Riki Tanaka, Akira Wakako, Kiyonori Kuwahara, Tsukasa Ganaha, Yuichi Hirose Grade V subarachnoid haemorrhage (SAH) patients may be dichotomised into those with temporary deterioration and those with irreversible injury, and only the former have a chance of favourable outcomes by aneurysm obliteration. One method of differentiating the two conditions is to wait and observe potential recovery for 12–48hours. However, early r...
Source: Journal of Clinical Neuroscience - July 21, 2016 Category: Neuroscience Source Type: research

Bone scintigraphy as cornerstone in the diagnosis of Erdheim –Chester disease
Publication date: May–June 2016 Source:Revista Española de Medicina Nuclear e Imagen Molecular (English Edition), Volume 35, Issue 3 Author(s): F.J. García-Gómez, T. Cambil-Molina, J.J. Ríos-Martín, P.A. de la Riva-Pérez, C. Calvo-Morón, J. Castro-Montaño The Erdheim–Chester disease (ECD) is an extremely rare form of non-Langerhans cell histiocytosis. The main difficulty for its diagnosis lies in the wide variety of non-specific symptoms and signs that can occur in the disease process, leading, therefore, to there being no clear-cut algorithm as a guide for an optimal biopsy to confirm the diagnosis. An...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - July 21, 2016 Category: Nuclear Medicine Source Type: research

Aspirin or Nonsteroidal Anti-inflammatory Drug –Exacerbated Chronic Rhinosinusitis
Publication date: July–August 2016 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 4, Issue 4 Author(s): Dennis K. Ledford, Richard F. Lockey Aspirin (ASA)-exacerbated respiratory disease (AERD) is characterized by upper airway congestion due to eosinophilic inflammation of the nasal and sinus membranes and nasal polyposis, associated with increased leukotriene production that is further accentuated by ASA or other nonsteroidal anti-inflammatory drug (NSAID) ingestion. It occurs in 5% to 10% of subjects with chronic rhinosinusitis (CRS) and in 15% to 40% of those with nasal polyposis. Altho...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 21, 2016 Category: Allergy & Immunology Source Type: research

New aspects of controlled release systems for local anaesthetics: A  review
Publication date: Available online 17 June 2016 Source:Trends in Anaesthesia and Critical Care Author(s): Alexandru Florin Rogobete, Monica Dragomirescu, Ovidiu Horea Bedreag, Dorel Sandesc, Carmen Alina Cradigati, Mirela Sarandan, Marius Papurica, Sonia Elena Popovici, Corina Vernic, Gabriela Preda Pharmacological pain control and management applied in this medical area represent the gold goal for anaesthesia and intensive care units. One of the most common methods for pain control is the use of opioids. However, there are a number of complications and side effects induced by prolonged systemic administration ...
Source: Trends in Anaesthesia and Critical Care - July 21, 2016 Category: Anesthesiology Source Type: research

Qingfei Xiaoyan Wan, a traditional Chinese medicine formula, ameliorates Pseudomonas aeruginosa –induced acute lung inflammation by regulation of PI3K/AKT and Ras/MAPK pathways
In this study, the effects of QF on Pseudomonas aeruginosa–induced acute pneumonia in mice were evaluated. The mechanisms by which four typical anti-inflammatory ingredients from QF, arctigenin (ATG), cholic acid (CLA), chlorogenic acid (CGA) and sinapic acid (SPA), regulate anti-inflammatory signaling pathways and related targets were investigated using molecular biology and molecular docking techniques. The results showed that pretreatment with QF significantly inhibits the release of cytokines (TNF-α and IL-6) and chemokines (IL-8 and RANTES), reduces leukocytes recruitment into inflamed tissues and ameliorates pulmo...
Source: Acta Pharmaceutica Sinica B - July 21, 2016 Category: Cancer & Oncology Source Type: research

Precipitating Clinical Factors, Heart  Failure Characterization, and Outcomes in Patients Hospitalized With Heart Failure With Reduced, Borderline, and Preserved Ejection Fraction
Conclusions Potential precipitating factors among patients hospitalized with HF vary by EF group and are independently associated with clinical outcomes. (Source: JACC: Heart Failure)
Source: JACC: Heart Failure - July 21, 2016 Category: Cardiology Source Type: research

Nanobodies ®††Nanobody is a registered trademark of Ablynx NV. as inhaled biotherapeutics for lung diseases
Publication date: Available online 29 June 2016 Source:Pharmacology &amp; Therapeutics Author(s): Gino Van Heeke, Koen Allosery, Veronique De Brabandere, Tim De Smedt, Laurent Detalle, Antonin de Fougerolles Local pulmonary delivery of biotherapeutics may offer advantages for the treatment of lung diseases. Delivery of the therapeutic entity directly to the lung has the potential for a rapid onset of action, reduced systemic exposure and the need for a lower dose, as well as needleless administration. However, formulation of a protein for inhaled delivery is challenging and requires proteins with favorable biop...
Source: Pharmacology and Therapeutics - July 21, 2016 Category: Drugs & Pharmacology Source Type: research

Disseminated tuberculosis with prostatic abscesses in an immunocompromised patient —A case report and review of literature
We describe a case of disseminated Mycobacterium tuberculosis (mTB) with prostatic abscess in a newly diagnosed HIV patient in the United States. The patient is a 34 year-old male who presented with respiratory symptoms and was diagnosed with HIV/AIDS complicated by disseminated mTB infection of the lungs, liver, and prostate. His prostate showed abscess formation on imaging that required drainage however he did not present with any genitourinary complaints. Our literature review revealed that prostatic involvement in mTB in the form of granulomatous prostatitis is uncommon; however, abscess formation is extremely rare and...
Source: IDCases - July 21, 2016 Category: Infectious Diseases Source Type: research

Burkholderia mallei CLH001 Attenuated Vaccine Strain Is Immunogenic and Protects against Acute Respiratory Glanders [Microbial Immunity and Vaccines]
In this study, we constructed the select-agent-excluded B. mallei tonB hcp1 (CLH001) vaccine strain and investigated its ability to protect against acute respiratory glanders. Here we show that CLH001 is attenuated, safe, and effective at protecting against lethal B. mallei challenge. Intranasal administration of CLH001 to BALB/c and NOD SCID gamma (NSG) mice resulted in complete survival without detectable colonization or abnormal organ histopathology. Additionally, BALB/c mice intranasally immunized with CLH001 in a prime/boost regimen were fully protected against lethal challenge with the B. mallei lux (CSM001) wild-typ...
Source: Infection and Immunity - July 21, 2016 Category: Infectious Diseases Authors: Hatcher, C. L., Mott, T. M., Muruato, L. A., Sbrana, E., Torres, A. G. Tags: Microbial Immunity and Vaccines Source Type: research

A unique case of right cervical aortic arch with anomalous left common carotid artery and absent right common carotid artery
Conclusion Cervical aortic arch is not a very commonly encountered entity and can be quite vexing for those who are seeing such a case in OPD for the first time. Although cervical aortic arch anomalies have been reported in literature, published reports of new cases will help to increase awareness regarding this anomaly and lead to a swift and efficient diagnosis and management. (Source: Annals of Medicine and Surgery)
Source: Annals of Medicine and Surgery - July 21, 2016 Category: Journals (General) Source Type: research

Morning and night symptoms in primary care COPD patients: a cross-sectional and longitudinal study. An UNLOCK study from the IPCRG
npj Primary Care Respiratory Medicine, Published online: 21 July 2016; doi:10.1038/npjpcrm.2016.40 (Source: npj Primary Care Respiratory Medicine)
Source: npj Primary Care Respiratory Medicine - July 21, 2016 Category: Primary Care Authors: Ioanna Tsiligianni Esther Metting Thys van der Molen Niels Chavannes Janwillem Kocks Source Type: research

The frequency of, and adherence to, single maintenance and reliever therapy instructions in asthma: a descriptive analysis
npj Primary Care Respiratory Medicine, Published online: 21 July 2016; doi:10.1038/npjpcrm.2016.38 (Source: npj Primary Care Respiratory Medicine)
Source: npj Primary Care Respiratory Medicine - July 21, 2016 Category: Primary Care Authors: Rachael L DiSantostefano Nada Boudiaf David A Stempel Neil C Barnes Andrew P Greening Source Type: research

Current Disease and Epidemiologic Problems: What ’s Hot?
Publication date: May–July 2015 Source:New Horizons in Translational Medicine, Volume 2, Issues 4–5 Author(s): CH Calisher Included among the many current world problems are viral diseases of considerable significance and threat. This talk could not possible cover them all but will discuss the emergence of Middle East respiratory syndrome in Saudi Arabia and nearby countries, ebolavirus hemorrhagic fever in West Africa, chikungunya in the Western Hemisphere, and the re-emergence of poliomyelitis. (Source: New Horizons in Translational Medicine)
Source: New Horizons in Translational Medicine - July 21, 2016 Category: Research Source Type: research

Airway stenting in the management of iatrogenic tracheal injuries: 10 ‐Year experience
ConclusionConservative management should be considered in non‐ventilated patients with ITI and when ITI is located in the upper trachea of ventilated patients where ETT or TC bypasses the injury. Airway stenting should be considered in ventilated patients with ITI located in the lower trachea. Surgery should be reserved for TEF and conservative and endoscopic management failure. (Source: Respirology)
Source: Respirology - July 21, 2016 Category: Respiratory Medicine Authors: Rachid Tazi ‐Mezalek, Ali I. Musani, Sophie Laroumagne, Philippe J. Astoul, Xavier B. D'journo, Pascal A. Thomas, Hervé Dutau Tags: Original Article Source Type: research

Clinically remitted childhood asthma is associated with airflow obstruction in middle ‐aged adults
ConclusionClinically remitted childhood asthma is associated with airflow obstruction in middle‐aged adults. Smoking and remitted childhood asthma may be additive factors for the development of airflow obstruction. (Source: Respirology)
Source: Respirology - July 21, 2016 Category: Respiratory Medicine Authors: Keitaro Omori, Hiroshi Iwamoto, Takashi Yamane, Taku Nakashima, Yoshinori Haruta, Noboru Hattori, Akihito Yokoyama, Nobuoki Kohno Tags: Original Article Source Type: research

Editorial Board, Masthead, TOC
(Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - July 21, 2016 Category: Respiratory Medicine Tags: Issue Information Source Type: research

Upcoming events of interest
(Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - July 21, 2016 Category: Respiratory Medicine Tags: Upcoming Events Source Type: research

Innovative Tuberculosis Symposium held during Cuba Salud 2015
The Tuberculosis (TB) Symposium, held during the Cuba Salud 2015 International Convention, highlighted advancements in research on tuberculosis (TB) and Mycobacterium tuberculosis (MTBtb) by interdisciplinary teams from academic and federal institutions in Cuba, Colombia, Mexico, and the Dominican Republic. Delegates focused on the targets presented in the World Health Organization End TB Strategy for 2016-2035 and elaborated on four primary themes: 1) attention to vulnerable populations such as immunocompromised individuals, health care workers, and residents of long-term institutions such as prisons and nursing homes; 2)...
Source: Tuberculosis - July 21, 2016 Category: Respiratory Medicine Authors: Helena J. Chapman, Luisa Armas P érez Tags: Editorial Source Type: research

Safety and immunogenicity of the M72/AS01E candidate tuberculosis vaccine in adults with tuberculosis: a phase II randomised study
Previous studies have shown that the M72/AS01E candidate tuberculosis vaccine is immunogenic with a clinically acceptable safety profile in healthy and Mycobacterium tuberculosis-infected adults. This phase II, observer-blind, randomised study compared the safety, reactogenicity, and immunogenicity of M72/AS01E in 3 cohorts: tuberculosis-na ïve adults (n=80), adults previously treated for tuberculosis (n=49), and adults who have completed the intensive phase of tuberculosis treatment (n=13).In each cohort, 18–59-year-old adults were randomised (1:1) to receive two doses of M72/AS01E (n=71) or placebo (n=71) and followed...
Source: Tuberculosis - July 21, 2016 Category: Respiratory Medicine Authors: Paul Gillard, Pan-Chyr Yang, Manfred Danilovits, Wei-Juin Su, Shih-Lung Cheng, Lea Pehme, Anne Bollaerts, Erik Jongert, Philippe Moris, Opokua Ofori-Anyinam, Marie-Ange Demoiti é, Marcela Castro Tags: Immunological Aspects Source Type: research

TBDRUGS - Database of Drugs for Tuberculosis
Tuberculosis (TB) continues to be a major killer disease worldwide, though it can be cured completely. Emergence of drug resistant tuberculosis (DR-TB) has made TB treatment a complex one, demanding intake of medicine for about 2 years versus 6 months for drug-sensitive tuberculosis. Further, the success rate of treatment of DR-TB is reported to be very poor (48%) as compared to drug-sensitive new TB cases (around 90%) [1]. However, the recent approval of bedaquiline and delamanid for use against drug resistant tuberculosis, and the prospect of several candidate drugs in the pipeline with demonstrated activity against DR-T...
Source: Tuberculosis - July 21, 2016 Category: Respiratory Medicine Authors: Jagadish Chandrabose Sundaramurthi, Luke Elizabeth Hanna, Sriram Selvarajulu, Sridharan Brindha, Joel Gnanadoss J, Savariar Vincent, Harpreet Singh, Soumya Swaminathan Tags: Letter to the Editor Source Type: research

Diagnostic and prognostic significance of receptor ‐binding cancer antigen expressed on SiSo cells in lung‐cancer‐associated pleural effusion
ConclusionIn conclusion, measurement of sRCAS1 might be a useful diagnostic and prognostic marker for MPE. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - July 21, 2016 Category: Respiratory Medicine Authors: Jian Yang, Ying Zhu, Liangquan Wu, Wenyan Zhu, Xiuwei Zhang, Yang Yang, Chunhua Xu Tags: Original Article Source Type: research

Determinants of delay in tuberculosis diagnosis in Hamadan province, 2006 −2014
Conclusion A high proportion of patients had delays in diagnosis exceeding three months. Our findings suggest that male gender, new cases, positive and extra pulmonary cases might increase the risk for delayeddiagnosis among TB patients. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - July 21, 2016 Category: Respiratory Medicine Source Type: research

Sputum –plasma ratio of soluble receptor for advanced glycation end-products in patients with chronic obstructive pulmonary disease
Conclusions sRAGE level either in induced sputum, plasma or sputum plasma ratio is not significantly different between stable COPD patients, smokers and healthy controls. Thus, sRAGE cannot be considered as a marker of either diagnosis or severity of COPD. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - July 21, 2016 Category: Respiratory Medicine Source Type: research

Pulmonary tuberculosis epidemiology in Coimbra's District (2000 –2011): Information is essential to understand high risk groups
Publication date: July–August 2016 Source:Revista Portuguesa de Pneumologia (English Edition), Volume 22, Issue 4 Author(s): R. Eufrásio, M. Alcobia, L. Correia (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - July 21, 2016 Category: Respiratory Medicine Source Type: research

Pleural effusion cytology due to malignancy. A combined cytomorphological –immunocytochemical study of 500 cases
Publication date: Available online 20 May 2016 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): A. Kalogeraki, D. Tamiolakis, G. Datseri, G. Lazopoulos, M. Karvelas-Kalogerakis, J. Segredakis, I. Zoi (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - July 21, 2016 Category: Respiratory Medicine Source Type: research

A case of Birt –Hogg–Dubé syndrome
Publication date: Available online 14 May 2016 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): L. Martins, M. Caixeiro, C. Costa, S. Feijó, C. Bárbara (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - July 21, 2016 Category: Respiratory Medicine Source Type: research

Simulated Trauma and Resuscitation Team Training course —evolution of a multidisciplinary trauma crisis resource management simulation course
Conclusions The evolved Simulated Trauma and Resuscitative Team Training curriculum has maintained high participant satisfaction and is associated with improvement in team crisis resource management skills over the duration of the course. (Source: The American Journal of Surgery)
Source: The American Journal of Surgery - July 21, 2016 Category: Surgery Source Type: research

Extracorporeal Membrane Oxygenation —What the Nephrologist Needs to Know
Publication date: May 2016 Source:Advances in Chronic Kidney Disease, Volume 23, Issue 3 Author(s): Andres Oswaldo Razo-Vazquez, Kevin Thornton Extracorporeal membrane oxygenation (ECMO) use in adults is rapidly increasing in its use for both cardiac and respiratory failure. ECMO exists in 2 primary configurations: veno-venous ECMO, used in the setting of isolated respiratory failure, and veno-arterial ECMO, which can be used in respiratory failure but is mandatory in the setting of cardiac failure. Acute kidney injury occurs frequently in patients on ECMO, and renal replacement therapy is often required. Continuous fo...
Source: Advances in Chronic Kidney Disease - July 21, 2016 Category: Urology & Nephrology Source Type: research

Fractional Exhaled Nitric Oxide for the Diagnosis of Childhood Asthma: a Systematic Review and Meta-analysis
< h3 class= " a-plus-plus " > Abstract < /h3 > < p class= " a-plus-plus " > The gold standard for diagnosing asthma in children is based on clinical history of respiratory symptoms, physical examination, and respiratory function testing. Recent advances indicate that a non-invasive measure of airway inflammation, fractional exhaled nitric oxide (FeNO), provides objective data for use in asthma diagnosis. However, the diagnostic performance of FeNO in children with asthma has not been clearly defined. This systematic review and meta-analysis aimed to evaluate the diagnostic accuracy of FeNO in the clinical determination of ...
Source: Clinical Reviews in Allergy and Immunology - July 21, 2016 Category: Allergy & Immunology Source Type: research

Lung Function Abnormalities in Smokers With Ischemic Heart Disease.
CONCLUSIONS: Airflow limitation compatible with chronic obstructive pulmonary disease affects almost one-third of patients with ischemic heart disease. While airflow limitation is associated with additional morbidity and societal burden, it is largely undiagnosed and untreated. Clinical trial registration available at www.clinicaltrials.gov, ID NCT01485159. PMID: 27442601 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - July 21, 2016 Category: Respiratory Medicine Authors: Franssen FM, Soriano JB, Roche N, Bloomfield PH, Brusselle G, Fabbri LM, García-Rio F, Kearney MT, Kwon N, Lundbäck B, Rabe KF, Raillard A, Muellerova H, Cockcroft JR Tags: Am J Respir Crit Care Med Source Type: research

Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction
The loss of strength in combination with constant fatigue is a burden on cancer patients undergoing chemotherapy. Doxorubicin, a standard chemotherapy drug used in the clinic, causes skeletal muscle dysfunction and increases mitochondrial H2O2. We hypothesized that the combined effect of cancer and chemotherapy in an immunocompetent breast cancer mouse model (E0771) would compromise skeletal muscle mitochondrial respiratory function, leading to an increase in H2O2-emitting potential and impaired muscle function. Here, we demonstrate that cancer chemotherapy decreases mitochondrial respiratory capacity supported with comple...
Source: AJP: Endocrinology and Metabolism - July 21, 2016 Category: Endocrinology Authors: Gilliam, L. A. A., Lark, D. S., Reese, L. R., Torres, M. J., Ryan, T. E., Lin, C.-T., Cathey, B. L., Neufer, P. D. Tags: Call for Papers Source Type: research

Accuracy and precision of quantitative 31P-MRS measurements of human skeletal muscle mitochondrial function
Although theoretically sound, the accuracy and precision of 31P-magnetic resonance spectroscopy (31P-MRS) approaches to quantitatively estimate mitochondrial capacity are not well documented. Therefore, employing four differing models of respiratory control [linear, kinetic, and multipoint adenosine diphosphate (ADP) and phosphorylation potential], this study sought to determine the accuracy and precision of 31P-MRS assessments of peak mitochondrial adenosine-triphosphate (ATP) synthesis rate utilizing directly measured peak respiration (State 3) in permeabilized skeletal muscle fibers. In 23 subjects of different fitness ...
Source: AJP: Endocrinology and Metabolism - July 21, 2016 Category: Endocrinology Authors: Layec, G., Gifford, J. R., Trinity, J. D., Hart, C. R., Garten, R. S., Park, S. Y., Le Fur, Y., Jeong, E.-K., Richardson, R. S. Tags: Articles Source Type: research

Hospital Surveillance of Influenza Strains: A Concordant Image of Viruses Identified by the Swiss Sentinel System?
CONCLUSIONS: Although an influenza surveillance system based on the community can predict the type of influenza strains that will be associated with hospitalizations, it fails to estimate the potential virulence of circulating strains. Further, the population characteristics in the community differ from those in hospitalized patients. This suggests that any national influenza surveillance system should include both community and hospital-based surveys. This article is protected by copyright. All rights reserved. PMID: 27441401 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - July 21, 2016 Category: Respiratory Medicine Authors: Gonçalves AR, Iten A, Suter-Boquete P, Schibler M, Kaiser L, Cordey S Tags: Influenza Other Respir Viruses Source Type: research

Epidemiology and Clinical Characteristics of Respiratory Syncytial Virus Infections among Children and Adults in Mexico.
CONCLUSIONS: This study confirms that RSV is an important respiratory pathogen in children in Mexico. In addition, a substantial number of cases in adults were also detected highlighting the relevance of this virus in all ages. It is important to identify subjects at high risk of complications who may benefit from current or future preventive interventions. This article is protected by copyright. All rights reserved. PMID: 27439650 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - July 21, 2016 Category: Respiratory Medicine Authors: Gamiño-Arroyo AE, Moreno-Espinosa S, Llamosas-Gallardo B, Ortiz-Hernández AA, Guerrero ML, Galindo-Fraga A, Galán-Herrera JF, Prado-Galbarro FJ, Beigel JH, Ruiz-Palacios GM, Noyola DE, Mexico Emerging Infectious Diseases Clinical Research Network (La R Tags: Influenza Other Respir Viruses Source Type: research