Respiratory Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 14.
Secondary peripheral ameloblastic carcinoma of the palate: A case report and literature review
We describe the case of an 82-year-old male referred to our department with a hemorrhagic mass on the right palate that developed 6–7 years earlier. Clinical examination revealed a mass 40×30×10mm in size affecting the hard palate that exhibited relatively clear boundaries, granular superficial appearance, and hemorrhaging. Computed tomography and magnetic resonance imaging revealed compressive resorption of the bone surface in contact with the tumor. A biopsy was performed; the histopathological diagnosis of the biopsy was peripheral ameloblastoma without any findings of malignancy. The patient subsequently underwent ...
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - April 27, 2016 Category: ENT & OMF Source Type: research
Middle East respiratory syndrome in South Korea during 2015: Risk-related perceptions and quarantine attitudes
Publication date: Available online 26 April 2016 Source:American Journal of Infection Control Author(s): E.Y. Kim, Q. Liao, E.S. Yu, J.H. Kim, S.W. Yoon, W.W.T. Lam, R. Fielding A telephone survey involving 200 household members in and around Seoul, South Korea, was completed during the maturity stage of the outbreak of Middle East respiratory syndrome (MERS) in Korea during June 2015. The study found that respondents perceived low risk from contracting MERS, had low trust in government in controlling MERS, and generally held unfavorable attitudes toward quarantine. (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - April 27, 2016 Category: Infectious Diseases Source Type: research
Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial
Publication date: Available online 27 April 2016 Source:The Lancet Author(s): Sally Wenzel, Mario Castro, Jonathan Corren, Jorge Maspero, Lin Wang, Bingzhi Zhang, Gianluca Pirozzi, E Rand Sutherland, Robert R Evans, Vijay N Joish, Laurent Eckert, Neil M H Graham, Neil Stahl, George D Yancopoulos, Mariana Louis-Tisserand, Ariel Teper Background Dupilumab, a fully human anti-interleukin-4 receptor α monoclonal antibody, inhibits interleukin-4 and interleukin-13 signalling, key drivers of type-2-mediated inflammation. Adults with uncontrolled persistent asthma who are receiving medium-to-high-dose inhaled c...
Source: The Lancet - April 27, 2016 Category: Journals (General) Source Type: research
Oral pressure therapy (winx) for obstructive sleep apnea: a meta-analysis updating the systematic review
(Source: Sleep and Breathing)
Source: Sleep and Breathing - April 27, 2016 Category: Respiratory Medicine Source Type: research
Lung cancer in patients diagnosed with silicosis should be investigated
Publication date: Available online 27 April 2016 Source:Respiratory Medicine Case Reports Author(s): Adil Can Güngen, Yusuf Aydemir, Hikmet Çoban, Hasan Düzenli, Canantan Tasdemir Silicosis is an interstitial lung disease developing as a result of inhalation of inorganic silica particles. In silicosis cases developing as a result of environmental and occupational exposure, an increase is observed in Turkey especially depending upon denim sandblasting. We present a 35-year-old female case who was applied to our hospital due to complaint of progressive dyspnea, had a history of working in denim sandblasting for 18 ...
Source: Respiratory Medicine Case Reports - April 27, 2016 Category: Respiratory Medicine Source Type: research
Elemental analysis of occupational granulomatous lung disease by electron probe microanalyzer with wavelength dispersive spectrometer: Two case reports
We reported two cases of granulomatous lung disease with occupational exposure to metal dusts other than beryllium. They had worked in the battery manufacturing industry for 7 years and in an aluminum-processing factory for 6 years, respectively. Chest high-resolution computed tomography showed diffuse micronodules, and histology of video-assisted lung biopsy specimens revealed granulomatous lesions in the pulmonary interstitium. Results of microscopic examination of the tissue with special stains for mycobacteria and fungi were negative. Analysis by an electron probe microanalyzer with a wavelength-dispersive spectrometer...
Source: Respiratory Medicine Case Reports - April 27, 2016 Category: Respiratory Medicine Source Type: research
Intra-operative adherence to lung-protective ventilation: a prospective observational study
Conclusions Perioperative lung protection ventilation can improve patient outcomes from major surgery. This large prospective study demonstrates that within the West Midlands lung-protective ventilation during the perioperative period is uncommon, especially in relation to the use of PEEP, and that perhaps further trials are required to promote wider adoption of practice. (Source: Perioperative Medicine)
Source: Perioperative Medicine - April 27, 2016 Category: Surgery Source Type: research
Effects of internal iliac artery embolization on systemic inflammatory response syndrome in dogs with simulated-pelvic-fracture combined with massive bleeding
Conclusion Through the use of an on-spot interventional treatment cabin, early internal iliac artery embolization can control bleeding associated with pelvic fractures, delay the occurrence of SIRS, and improve the success rate of the treatment of pelvic fracture combined with bleeding. (Source: Military Medical Research)
Source: Military Medical Research - April 27, 2016 Category: Global & Universal Source Type: research
Change of serum prealbumin levels and serum protein markers between egg white powder and casein protein additives in standard enteral feeding formulas in critically ill patients with acute respiratory failure
Conclusions The levels of PAB between the egg white protein additive and casein protein additive were not significantly different and less than the non-inferior margin. Trial registration Thai Clinical Trials Registry TCTR20160126002 (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - April 27, 2016 Category: Intensive Care Source Type: research
Equid lumbar evolution
This study tests the hypothesis that stiff-backed running in horses evolved in response to evolutionary increases in body size by examining lumbar joint shape from a broad sample of fossil equids in a phylogenetic context. Lumbar joint shape scaling suggests that stability of the lumbar region does correlate with size through equid evolution. However, scaling effects were dampened in the posterior lumbar region, near the sacrum, which suggests strong selection for sagittal mobility in association with locomotor–respiratory coupling near the lumbosacral joint. I hypothesize that small-bodied fossil horses may have use...
Source: Proceedings of the Royal Society B: Biological Sciences - April 27, 2016 Category: Biology Authors: Jones, K. E. Tags: palaeontology, biomechanics, evolution Research articles Source Type: research
Yoga for asthma.
CONCLUSIONS: We found moderate-quality evidence that yoga probably leads to small improvements in quality of life and symptoms in people with asthma. There is more uncertainty about potential adverse effects of yoga and its impact on lung function and medication usage. RCTs with a large sample size and high methodological and reporting quality are needed to confirm the effects of yoga for asthma. PMID: 27115477 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 27, 2016 Category: Journals (General) Authors: Yang ZY, Zhong HB, Mao C, Yuan JQ, Huang YF, Wu XY, Gao YM, Tang JL Tags: Cochrane Database Syst Rev Source Type: research
Surfactant Treatment Threshold during NCPAP for the Treatment of Preterm Infants with Respiratory Distress Syndrome
In conclusion, although current data seem to suggest that low threshold is better than high threshold, additional studies are necessary to identify the most effective criteria for selective surfactant treatment of preterm infants with RDS.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents | Abstract | Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 27, 2016 Category: Perinatology & Neonatology Authors: Dani, Carlo Tags: Review Article Source Type: research
Clinical and Immunological Benefits of OM-85 Bacterial Lysate in Patients with Allergic Rhinitis, Asthma, and COPD and Recurrent Respiratory Infections
Conclusions Our results showed the clinical benefits of OM-85 in reducing RTIs and exacerbations of the underlying medical condition, in patients with allergic rhinitis, asthma, or COPD. (Source: Lung)
Source: Lung - April 27, 2016 Category: Respiratory Medicine Source Type: research
Ascorbic Acid Attenuates Hyperoxia-Compromised Host Defense Against Pulmonary Bacterial Infection.
Abstract Supraphysiological concentrations of oxygen (hyperoxia) can compromise host defense and increase susceptibility to bacterial infections, causing ventilator-associated pneumonia (VAP). The phagocytic activity of macrophages is impaired by hyperoxia-induced increases in the levels of reactive oxygen species (ROS) and extracellular high mobility group protein B1 (HMGB1). Ascorbic acid (AA), an essential nutrient and antioxidant, has been shown to be beneficial in various animal models of ROS-mediated diseases. The aim of this study was to determine whether AA could attenuate hyperoxia-compromised host defense...
Source: American Journal of Respiratory Cell and Molecular Biology - April 27, 2016 Category: Molecular Biology Authors: Patel VS, Sampat V, Espey MG, Sitapara R, Wang H, Yang X, Ashby CR, Thomas DD, Mantell LL Tags: Am J Respir Cell Mol Biol Source Type: research
Rhinovirus Delays Cell Repolarization in a Model of Injured/Regenerating Human Airway Epithelium.
In this study, we examined the effects of RV on cell repolarization and differentiation in a model of injured/regenerating airway epithelium (polarized, undifferentiated cells). RV causes only a transient barrier disruption in a model of normal (mucociliary-differentiated) airway epithelium. However, in the injury/regeneration model, RV prolongs barrier dysfunction and alters differentiation of cells. The prolonged barrier dysfunction caused by RV was not due to excessive cell death but was instead associated with epithelial-to-mesenchymal transition (EMT)-like features, such as reduced expression of the apicolateral junct...
Source: American Journal of Respiratory Cell and Molecular Biology - April 27, 2016 Category: Molecular Biology Authors: Faris AN, Ganesan S, Chattoraj A, Chattoraj SS, Comstock AT, Unger BL, Hershenson MB, Sajjan US Tags: Am J Respir Cell Mol Biol Source Type: research
Caspase-1 Activation Protects Lung Endothelial Barrier Function During Infection-induced Stress.
CONCLUSIONS: Caspase-1 is a sentinel stress response regulator that initiates pro-inflammatory responses and also initiates novel response(s) to protect PMVEC barrier function during pneumonia. PMID: 27119735 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - April 27, 2016 Category: Molecular Biology Authors: Alvarez DF, Housley N, Koloteva A, Zhou C, O'Donnell K, Audia JP Tags: Am J Respir Cell Mol Biol Source Type: research
Long-term adverse effects on reproductive function in male rats exposed prenatally to the glucocorticoid betamethasone.
Abstract Betamethasone is the drug of choice for antenatal treatment, promoting fetal lung maturation, decreasing the incidence of respiratory distress syndrome and neonatal mortality. Previous studies reported that prenatal treatment with this drug reduced testosterone levels, sperm quality and fertility in adult rats. We aimed to further evaluate the reproductive consequences of prenatal betamethasone exposure in male rats. Pregnant Wistar rats (n=13/group) were separated into two groups: control (vehicle) and betamethasone- treated (0.1mg/kg IM) and rats were injected on gestational days 12, 13, 18 and 19. Body ...
Source: Toxicology - April 27, 2016 Category: Toxicology Authors: Dos S Borges C, Dias AF, Silva PV, Rosa JL, Guerra MT, Silva RF, Kiguti LR, Pupo AS, De G Kempinas W Tags: Toxicology Source Type: research
Effects of individual and neighborhood socioeconomic status on the risk of all-cause mortality in chronic obstructive pulmonary disease: A nationwide population-based cohort study, 2002-2013.
CONCLUSIONS: Socioeconomic disparity contributes to all-cause mortality in COPD patients and neighborhood deprivation exacerbates the effect of individual SES on all-cause mortality in COPD patients. PMID: 27109806 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: Cho KH, Nam CM, Lee EJ, Choi Y, Yoo KB, Lee SH, Park EC Tags: Respir Med Source Type: research
Effect of tiotropium on COPD exacerbations: A systematic review.
CONCLUSIONS: The results of this comprehensive systematic review demonstrate tiotropium is beneficial in reducing exacerbation risk versus placebo or other maintenance treatments. PMID: 27109805 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: Halpin DM, Vogelmeier C, Pieper MP, Metzdorf N, Richard F, Anzueto A Tags: Respir Med Source Type: research
A nationwide epidemiological survey of alpha1-antitrypsin deficiency in Japan.
CONCLUSIONS: This nationwide survey confirmed that AATD is extremely rare in Japan. Six of 10 care-giving physicians would offer AAT augmentation therapy if the therapy were covered by health insurance in Japan. PMID: 27108016 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: Seyama K, Hirai T, Mishima M, Tatsumi K, Nishimura M, Respiratory Failure Research Group of the Japanese Ministry of Health, Labour, and Welfare Tags: Respir Investig Source Type: research
Comparison of oxygen uptake during cycle ergometry with and without functional electrical stimulation in patients with COPD: protocol for a randomised, single-blind, placebo-controlled, cross-over trial.
CONCLUSIONS: Approval has been granted by our Institutional Review Board (Comité de Protection des Personnes Nord-Ouest 3). The results of the trial will be presented at national and international meetings and published in peer-reviewed journals. TRIAL REGISTRATION NUMBER: NCT02594722. PMID: 27110364 [PubMed] (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: Medrinal C, Prieur G, Debeaumont D, Robledo Quesada A, Combret Y, Quieffin J, Contal O, Lamia B Tags: BMJ Open Respir Res Source Type: research
Assessment of sleep quality post-hospital discharge in survivors of critical illness.
CONCLUSIONS: Reduced sleep quality following critical illness is common and associated with reduced health related quality of life. Critical illness severity is a predictor of reduced sleep duration and sleep disruption 3 months after hospital discharge. This cohort study highlights the important role sleep may contribute to the long-term recovery from critical illness. PMID: 27109818 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: Solverson KJ, Easton PA, Doig CJ Tags: Respir Med Source Type: research
Gender inequalities in COPD decision-making in primary care.
CONCLUSIONS: There may be gender inequalities in primary care for COPD in our setting. Diagnostic and therapeutic efforts appear lower in female patients. Male and female FPs only differed in care of the male patient, indicating FP gender-patient gender interaction. PMID: 27109817 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: Delgado A, Saletti-Cuesta L, López-Fernández LA, Gil-Garrido N, Luna Del Castillo Jde D Tags: Respir Med Source Type: research
Decreased physical activity in adults with bronchial asthma.
Abstract Contradictory findings have been reported in the literature on the impact that bronchial asthma may have on habitual physical activity. The present study was designed to compare physical activity, objectively measured with an activity monitor, between adults with bronchial asthma and apparently healthy controls. Valid registrations of physical activity were obtained in 226 patients with asthma and 201 healthy controls. A multiple general linear model was used to test between group differences and to correct for confounding of the results due to between group differences in BMI and employment status. In the...
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: van 't Hul AJ, Frouws S, van den Akker E, van Lummel R, Starrenburg-Razenberg A, van Bruggen A, Braunstahl GJ, In 't Veen JC Tags: Respir Med Source Type: research
Predictors of survival in coexistent hypersensitivity pneumonitis with autoimmune features.
CONCLUSIONS: Fifteen percent of patients with chronic, fibrotic HP displayed evidence of a concurrent defined autoimmune disease or autoimmune features suggestive of CTD. The presence of autoimmunity in patients with chronic, fibrotic HP may portend a poorer prognosis. Future studies are needed to validate these findings and determine the impact of immunosuppressive treatment. PMID: 27109811 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: Adegunsoye A, Oldham JM, Demchuk C, Montner S, Vij R, Strek ME Tags: Respir Med Source Type: research
Associations of cognition with physical functioning and health-related quality of life among COPD patients.
CONCLUSIONS: Cognitive function was not associated with most standard indicators of physical function or most measures of HRQL in COPD patients. Both TMT-A and TMT-B were associated with weaker grip strength, and the TMT-A and MIS with poorer mental health. PMID: 27109810 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: Schure MB, Borson S, Nguyen HQ, Trittschuh EH, Thielke SM, Pike KC, Adams SG, Fan VS Tags: Respir Med Source Type: research
Lung cancer diagnosed following an emergency admission: Mixed methods study of the management, outcomes and needs and experiences of patients and carers.
CONCLUSIONS: Presentation as an EA does not appear to confer any inherent disadvantage regarding progress through lung cancer diagnostic and treatment pathways. However, given the frequent combination of advanced disease, poor performance status and prognosis, together with the high level of need and reported short-fall in care, we suggest that a specialist palliative care assessment is routinely offered. PMID: 27109809 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: Wilcock A, Crosby V, Hussain A, McKeever TM, Manderson C, Farnan S, Freer S, Freemantle A, Littlewood F, Caswell G, Seymour J Tags: Respir Med Source Type: research
The German COPD cohort COSYCONET: Aims, methods and descriptive analysis of the study population at baseline.
CONCLUSION: The German COPD cohort comprises patients with advanced and less advanced COPD. This is particularly useful for studying the time course of COPD in relation to comorbidities. Baseline data indicate that COSYCONET offers the opportunity to investigate our research questions in a large-scale, high-quality dataset. PMID: 27109808 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: Karch A, Vogelmeier C, Welte T, Bals R, Kauczor HU, Biederer J, Heinrich J, Schulz H, Gläser S, Holle R, Watz H, Korn S, Adaskina N, Biertz F, Vogel C, Vestbo J, Wouters EF, Rabe KF, Söhler S, Koch A, Jörres RA, COSYCONET Study Group Tags: Respir Med Source Type: research
Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study.
CONCLUSIONS: The ADEPT cohort showed group stability, individual stability in some parameters e.g. low FEV1/FVC ratio, and low FENO, but marked individual variability in other clinical characteristics and biomarkers e.g. type-2 biomarkers over 12 months. This variability is possibly related to seasonal variations in climate and allergen exposure, medication changes and acute exacerbations. The implications for patient selection strategies based on clinical biomarkers may be considerable. PMID: 27107814 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 26, 2016 Category: Respiratory Medicine Authors: Silkoff PE, Laviolette M, Singh D, FitzGerald JM, Kelsen S, Backer V, Porsbjerg C, Girodet PO, Berger P, Kline JN, Khatri S, Chanez P, Susulic VS, Barnathan ES, Baribaud F, Loza MJ, ADEPT Investigators Tags: Respir Res Source Type: research
Endocan: A Novel Predıctor of Endothelıal Dysfunctıon ın Obstructıve Sleep Apnea Syndrome
Conclusion: Serum endocan level is strongly associated with the severity of OSA and endothelial dysfunction. Endocan might be a useful early novel marker for premature vascular endothelial system damage in OSA patients. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 26, 2016 Category: Respiratory Medicine Authors: Asiye Kanbay, Erkan Ceylan, Handan İnönü Köseoğlu, Mustafa Çalışkan, Mumtaz Takir, Selcan Tulu, Ozge Telci Çaklılı, Osman Köstek, Aybala Erek, Baris Afsar Tags: Original Article Source Type: research
Neonatal hyperoxia increases airway reactivity and inflammation in adult mice
ConclusionsExposure to hyperoxia in newborn mice increases long‐term airway reactivity with persistent lung inflammation associated with a marked increase in lymphocytes, suggesting long‐term consequences in adults. Pediatr Pulmonol. © 2016 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - April 26, 2016 Category: Respiratory Medicine Authors: Vasantha H.S. Kumar, Satyan Lakshminrusimha, Sergei Kishkurno, Babu S. Paturi, Sylvia F. Gugino, Lori Nielsen, Huamei Wang, Rita M. Ryan Tags: Original Article Source Type: research
The association between gastroesophageal reflux disease and recurrent respiratory papillomatosis: A systematic review
ConclusionThere is insufficient proof that GERD does or does not aggravate the clinical course or tissue properties of RRP. Laryngoscope, 2016 (Source: The Laryngoscope)
Source: The Laryngoscope - April 26, 2016 Category: ENT & OMF Authors: Michel R.M. San Giorgi, Herman M. Helder, Robbert‐Jan S. Lindeman, Geertruida H. de Bock, Frederik G. Dikkers Tags: Laryngology Source Type: research
Mixed method exploration of the medical, service-related, and emotional reasons for emergency room visits of older cancer patients
Conclusions The study suggests areas of improvement to prevent ER visits when health issues can be addressed by other care services. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 26, 2016 Category: Cancer & Oncology Source Type: research