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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 15.

Influence of Diaphragmatic Motion on Inferior Vena Cava Diameter Respiratory Variations in Healthy Volunteers
Conclusions Inferior vena cava collapsibility is affected by diaphragmatic motion. During low inspiratory effort, diaphragmatic motion was less than 25 mm and predicted a cIVC less than 40%. During maximal inspiratory effort, diaphragmatic motion was more than 43 mm and predicted a cIVC more than 40%. When diaphragmatic motion ranged from 25 to 43 mm, no conclusion on cIVC value could be done. (Source: Anesthesiology)
Source: Anesthesiology - May 18, 2016 Category: Anesthesiology Source Type: research

The cardiopulmonary effects and quality of anesthesia after induction with alfaxalone in 2‐hydroxypropyl‐β‐cyclodextrin in dogs and cats: a systematic review
To systematically review the quality of evidence comparing the cardiopulmonary effects and quality of anesthesia after induction with alfaxalone vs. other anesthetic agents in dogs and cats. Studies published from 2001 until 20th May 2013 were identified with the terms ‘alfaxan’ OR ‘alfaxalone’ OR ‘alphaxalone’ in electronic databases: Discovery, PubMed, ScienceDirect, and Wiley Interscience. The study design and risk of bias of all included studies were assessed. Twenty‐two studies from 408 (22 of 408, 5.39%) satisfied the inclusion criteria. Fourteen studies (14 of 22, 64%) focused on dogs and nine (9 of 22...
Source: Journal of Veterinary Pharmacology and Therapeutics - May 18, 2016 Category: Veterinary Research Authors: K. W. Chiu, S. Robson, J. L. Devi, A. Woodward, T. Whittem Tags: Review Article Source Type: research

Breastfeeding and asthma outcomes at the age of 6 years: The Generation R Study
ConclusionsBreastfeeding patterns may influence wheezing and asthma in childhood, which seems to be partly explained by infectious mechanisms. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - May 18, 2016 Category: Allergy & Immunology Authors: Herman T. Dekker, Agnes M. M. Sonnenschein‐van der Voort, Vincent W. V. Jaddoe, Irwin K. Reiss, Johan C. Jongste, Liesbeth Duijts Tags: Original Article Source Type: research

Ludwig's angina
A 3-year-old boy presented with a 3-day history of fever, swelling in his neck, drooling of saliva and dysphagia. These symptoms were preceded by a 7-day history of an upper respiratory tract infection. On examination, the child was febrile, tachypnoeic and there was a diffuse, tender, firm and warm swelling in the submental and submandibular region of the neck with a swelling in the floor of the mouth displacing the tongue posteriorly (figure 1). A diagnosis of Ludwig's angina was made. The child underwent nasotracheal intubation with fibreoptic guidance and emergency decompression of the swelling using multiple incisions...
Source: Archives of Disease in Childhood - May 18, 2016 Category: Pediatrics Authors: Bakshi, S. S. Tags: Miscellanea Source Type: research

A qualitative study of sleep quality in children and their resident parents when in hospital
Conclusions Parents identified poor sleep in hospital as a significant additional burden to their child's hospital admission. Importantly, they identified potential improvements to the ward sleep environment. Intervention studies that target modifiable, child-centred alterations to night-time ward culture are recommended, focusing on measurable child and parental outcomes. (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - May 18, 2016 Category: Pediatrics Authors: Stickland, A., Clayton, E., Sankey, R., Hill, C. M. Tags: Immunology (including allergy), Epilepsy and seizures, Pain (neurology), Sleep disorders (neurology), Child health, Sleep disorders, Sleep disorders (respiratory medicine) Original article Source Type: research

A newborn with severe skeletal dysplasia
We present a newborn boy delivered at 39 weeks gestation with a prenatal diagnosis of skeletal dysplasia. He required endotracheal intubation and mechanical ventilation due to lack of respiratory effort. On physical examination, there was craniotabes, a bell-shaped chest, and brachymelic shortening of all four extremities. Radiographic studies showed lack of mineralisation of the skull except for the base, a small chest with very thin gracile and short ribs, extremely small and segmental regions of unmineralised vertebral bodies, and extremely short, dysplastic long bones with severe rachitic changes (figure 1). Quest...
Source: Archives of Disease in Childhood - Education and Practice - May 18, 2016 Category: Pediatrics Authors: Maalouf, F. I., Coggins, S. A., Phillips, J. A., Stefanescu, B. M., Weitkamp, J.-H. Tags: Immunology (including allergy), Epilepsy and seizures, Pregnancy, Reproductive medicine, Child health, Hospice, Mechanical ventilation, Rheumatology, Metabolic disorders Epilogue Source Type: research

Infants with artificially elevated pulse oximetry levels less likely to be hospitalised during an episode of mild to moderate bronchiolitis
Design: Double-blind single-centre randomised trial. Allocation: Concealed (web-based randomisation). Blinding: Emergency department physicians, nurses, families and research nurses were all blinded to group assignment. Study question Setting: Tertiary-care paediatric emergency department in Toronto. Patients: Previously healthy infants aged 4 weeks to 12 months diagnosed with mild to moderate bronchiolitis. Children with cardiopulmonary, neuromuscular, haematological or congenital airway anomalies, triage saturations <88%, severe respiratory distress or those transferred from other centres were excluded. Inte...
Source: Archives of Disease in Childhood - Education and Practice - May 18, 2016 Category: Pediatrics Authors: King, D., Dicks, R. A., Wacogne, I. D. Tags: Pancreas and biliary tract, Bronchiolitis, Picket, TB and other respiratory infections, Adult intensive care, Bronchitis, Cystic fibrosis, Interstitial lung disease Structured abstracts of sentinel articles: picket Source Type: research

1H MRS in the human spinal cord at 7 T using a dielectric waveguide transmitter, RF shimming and a high density receive array
Multimodal MRI is the state of the art method for clinical diagnostics and therapy monitoring of the spinal cord, with MRS being an emerging modality that has the potential to detect relevant changes of the spinal cord tissue at an earlier stage and to enhance specificity. Methodological challenges related to the small dimensions and deep location of the human spinal cord inside the human body, field fluctuations due to respiratory motion, susceptibility differences to adjacent tissue such as vertebras and pulsatile flow of the cerebrospinal fluid hinder the clinical application of 1H MRS to the human spinal cord. Compleme...
Source: NMR in Biomedicine - May 18, 2016 Category: Radiology Authors: A. Henning, W. Koning, A. Fuchs, A. Raaijmakers, J. J. Bluemink, C. A. T. Berg, V. O. Boer, D. W. J. Klomp Tags: Special issue research article Source Type: research

An assessment of quality of life of operated cases of esophageal atresia in the community
Conclusions: While survivals of the children born with EA have improved, these children still face nutritional, respiratory, and gastroesophageal problems during their early childhood. In spite of this, the overall QoL of this patient group appears good. (Source: Journal of Indian Association of Pediatric Surgeons)
Source: Journal of Indian Association of Pediatric Surgeons - May 18, 2016 Category: Surgery Authors: Harshjeet Singh BalSudipta SenSampath KarlJohn MathaiReju Joseph Thomas Source Type: research

Review of esophageal injuries and stenosis: Lessons learn and current concepts of management
Conclusion: Esophageal injuries though rare can be potentially devastating and life-threatening. (Source: Journal of Indian Association of Pediatric Surgeons)
Source: Journal of Indian Association of Pediatric Surgeons - May 18, 2016 Category: Surgery Authors: Raghu Sampalli RamareddyAnand Alladi Source Type: research

Is daily exposure to ozone associated with respiratory morbidity and lung function in a representative sample of schoolchildren? Results from a panel study in Greece
Is daily exposure to ozone associated with respiratory morbidity and lung function in a representative sample of schoolchildren? Results from a panel study in Greece Journal of Exposure Science and Environmental Epidemiology advance online publication, May 18 2016. doi:10.1038/jes.2016.32 Authors: Evangelia Samoli, Konstantina Dimakopoulou, Dimitris Evangelopoulos, Sophia Rodopoulou, Anna Karakatsani, Lambrini Veneti, Maria Sionidou, Ioannis Tsolakoglou, Ioanna Krasanaki, Georgios Grivas, Despoina Papakosta & Klea Katsouyanni (Source: Journal of Exposure Science and Environmental Epidemiology)
Source: Journal of Exposure Science and Environmental Epidemiology - May 18, 2016 Category: Epidemiology Authors: Evangelia SamoliKonstantina DimakopoulouDimitris EvangelopoulosSophia RodopoulouAnna KarakatsaniLambrini VenetiMaria SionidouIoannis TsolakoglouIoanna KrasanakiGeorgios GrivasDespoina PapakostaKlea Katsouyanni Tags: air pollution children ozone panel respiratory health Source Type: research

Molecules, Vol. 21, Pages 658: Cytotoxicity of Different Excipients on RPMI 2650 Human Nasal Epithelial Cells
The nasal route receives a great deal of attention as a non-invasive method for the systemic administration of drugs. For nasal delivery, specific formulations containing excipients are used. Because of the sensitive respiratory mucosa, not only the active ingredients, but also additives need to be tested in appropriate models for toxicity. The aim of the study was to measure the cytotoxicity of six pharmaceutical excipients, which could help to reach larger residence time, better permeability, and increased solubility dissolution rate. The following excipients were investigated on RPMI 2650 human nasal septum tumor epithe...
Source: Molecules - May 18, 2016 Category: Chemistry Authors: Tamás HorváthCsilla BartosAlexandra BocsikLóránd KissSzilvia VeszelkaMária DeliGabriella ÚjhelyiPiroska Szabó-RévészRita Ambrus Tags: Communication Source Type: research

Evaluating clinical mitochondrial respiratory chain enzymes from biopsy specimens presenting skewed probability distribution of activity data
Publication date: Available online 17 May 2016 Source:Mitochondrion Author(s): Milla-Riikka Hautakangas, Reetta Hinttala, Heikki Rantala, Pentti Nieminen, Johanna Uusimaa, Ilmo E. Hassinen Due to the relative rarity of mitochondrial diseases, generating reference ranges is problematic in evaluation of respiratory chain activities particularly in pediatric cases. We determined the sample distribution of respiratory chain enzyme activities in skeletal muscle biopsies collected from pediatric patients suspected of neuromuscular disorders. Activities of NADH-ubiquinone reductase, NADH-cytochrome c reductase, succinate-...
Source: Mitochondrion - May 18, 2016 Category: Biochemistry Source Type: research

Scaling of organelles and cells
We investigate the effects of trophic lifestyle and two types of major evolutionary transitions in individuality—the endosymbiotic acquisition of organelles and development of multicellularity—on organellar and cellular metabolism and allometry. We develop a quantitative framework linking the size and metabolic scaling of eukaryotic cells to the abundance, size and metabolic scaling of mitochondria and chloroplasts and analyse a newly compiled, unprecedented database representing unicellular and multicellular cells covering diverse phyla and tissues. Irrespective of cellularity, numbers and total volumes of mit...
Source: Proceedings of the Royal Society B: Biological Sciences - May 18, 2016 Category: Biology Authors: Okie, J. G., Smith, V. H., Martin-Cereceda, M. Tags: physiology, ecology, evolution Research articles Source Type: research

Extracorporeal carbon dioxide removal (ECCO 2 R) in respiratory deficiency and current investigations on its improvement: a review
Abstract The implementation of extracorporeal carbon dioxide removal (ECCO2R) as one of the extracorporeal life support system is getting more attention today. Thus, the objectives of this paper are to study the clinical practice of commercial ECCO2R system, current trend of its development and also the perspective on future improvement that can be done to the existing ECCO2R system. The strength of this article lies in its review scope, which focuses on the commercial ECCO2R therapy in the market based on membrane lung and current investigation to improve the efficiency of the ECCO2R system, in terms of surface m...
Source: Journal of Artificial Organs - May 18, 2016 Category: Transplant Surgery Source Type: research

Mycoplasma hyopneumoniae and Mycoplasma flocculare differential domains from orthologous surface proteins induce distinct cellular immune responses in mice
Publication date: Available online 17 May 2016 Source:Veterinary Microbiology Author(s): Fernanda Munhoz dos Anjos Leal, Veridiana Gomes Virginio, Carolina Lumertz Martello, Jéssica Andrade Paes, Thiago J. Borges, Natália Jaeger, Cristina Bonorino, Henrique Bunselmeyer Ferreira Mycoplasma hyopneumoniae and Mycoplasma flocculare are two genetically close species found in the swine respiratory tract. Despite their similarities, while M. hyopneumoniae is the causative agent of porcine enzootic pneumonia, M. flocculare is a commensal bacterium. Genomic and transcriptional comparative analyses so far failed to expla...
Source: Veterinary Microbiology - May 18, 2016 Category: Veterinary Research Source Type: research

Sequential Bilateral Bronchoscopic Lung Volume Reduction With One-Way Valves for Heterogeneous Emphysema
Conclusions A sequential bilateral approach seems to be a valid strategy to improve respiratory function in patients with bilateral heterogeneous emphysema who have lost the benefits obtained with the first procedure. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 18, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Inhalation of fifty percent oxygen reduces desaturation during midazolam sedation
To investigate how inhalation of 50% oxygen during intravenous midazolam sedation affects respiratory variables and hence the availability of oxygen. (Source: Journal of Oral and Maxillofacial Surgery)
Source: Journal of Oral and Maxillofacial Surgery - May 18, 2016 Category: ENT & OMF Authors: Aya Ninomiya, Nobuyuki Matsuura, Tatsuya Ichinohe Source Type: research

A PUFA-rich diet improves fat oxidation following saturated fat-rich meal
Conclusions Adopting a PUFA-rich diet initiates greater fat oxidation after eating occasional high SFA meals compared to a control diet, an effect achieved in 7 days. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - May 18, 2016 Category: Nutrition Source Type: research

The benefit of HH during the CPAP titration in the cool sleeping environment
Conclusions The use of HH is recommended during CPAP titration in the cool sleeping environment because of its benefit in the treatment of upper airway symptoms associated with CPAP therapy and improvement of the CPAP acceptance. (Source: Sleep and Breathing)
Source: Sleep and Breathing - May 18, 2016 Category: Respiratory Medicine Source Type: research

Validation of a Hindi version of the Epworth Sleepiness Scale (ESS) at AIIMS, New Delhi in sleep-disordered breathing
Conclusions The Hindi version of the ESS showed a good internal consistency and a strong correlation with the English version and can be used in the Hindi-speaking population. (Source: Sleep and Breathing)
Source: Sleep and Breathing - May 18, 2016 Category: Respiratory Medicine Source Type: research

Comparing Length of Stay Between Patients Taking Rivaroxaban and Conventional Anticoagulants for Treatment of Venous Thromboembolism
Conclusions In patients admitted with newly diagnosed VTE, those discharged on rivaroxaban had a significantly shorter LOS compared to those discharged on warfarin. In the appropriate subset of patients with VTE, treatment with rivaroxaban may result in significant cost savings for the hospital. (Source: Lung)
Source: Lung - May 18, 2016 Category: Respiratory Medicine Source Type: research

Pneumolysin Mediates Platelet Activation In Vitro
This study has explored the role of the pneumococcal toxin, pneumolysin (Ply), in activating human platelets. Following exposure to Ply (10–80 ng/ml), platelet activation and cytosolic Ca2+ concentrations were measured flow cytometrically according to the level of expression of CD62P (P-selectin) and spectrofluorimetrically, respectively. Exposure to Ply resulted in marked upregulation of expression of platelet CD62P, achieving statistical significance at concentrations of 40 ng/ml and higher (P < 0.05), in the setting of increased influx of Ca2+. These potentially pro-thrombotic actions of Ply were attenuated by ...
Source: Lung - May 18, 2016 Category: Respiratory Medicine Source Type: research

Trends in hospital admissions for obstructive lung disease from 2000 to 2010 in Portugal
The burden of hospitalisations for obstructive lung diseases (OLD) has not been sufficiently studied. We aimed to characterise the hospitalisations for OLD from 2000 to 2010 in all Portuguese public hospitals. We analysed hospital discharges with a diagnosis of OLD regarding the patients' gender, age, residence and comorbidities. Of the 120 399 hospital admissions with a principal diagnosis of OLD, COPD (ICD-9-CM 491.x, 492.x, 496.x) was responsible for 81%. The change in patients discharged with OLD as a principal diagnosis was only 1% from 2000 to 2010 and did not change for COPD. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - May 18, 2016 Category: Respiratory Medicine Authors: R. Vieira, J.A. Fonseca, F. Lopes, A. Freitas Source Type: research

Failure of NIMV and operator factor: when making things work, sometimes it is hard
(Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 18, 2016 Category: Respiratory Medicine Authors: Cüneyt Salturk, Antonio M. Esquinas, Tags: Letter to the Editor Source Type: research

The Effect of Inspiratory Muscle Training on Respiratory and Limb Locomotor Muscle Deoxygenation During Exercise with Resistive Inspiratory Loading
Int J Sports MedDOI: 10.1055/s-0042-104198We investigated how inspiratory muscle training impacted respiratory and locomotor muscle deoxygenation during submaximal exercise with resistive inspiratory loading. 16 male cyclists completed 6 weeks of either true (n=8) or sham (n=8) inspiratory muscle training. Pre- and post-training, subjects completed 3, 6-min experimental trials performed at ~80%  ˙VO2peak with interventions of either moderate inspiratory loading, heavy inspiratory loading, or maximal exercise imposed in the final 3 min. Locomotor and respiratory muscle oxy-, deoxy-, and total-haemoglobin and myoglobin ...
Source: International Journal of Sports Medicine - May 18, 2016 Category: Sports Medicine Authors: Turner, L. A.Tecklenburg-Lund, S. L.Chapman, R.Shei, R.-J.Wilhite, D. P.Mickleborough, T. Tags: Physiology & Biochemistry Source Type: research

Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial.
CONCLUSION: Twelve weeks of EGCG+RES supplementation increased mitochondrial capacity and stimulated fat oxidation compared with placebo, but this did not translate into increased tissue-specific insulin sensitivity in overweight and obese subjects. This trial was registered at clinicaltrials.gov as NCT02381145. PMID: 27194304 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - May 18, 2016 Category: Nutrition Authors: Most J, Timmers S, Warnke I, Jocken JW, van Boekschoten M, de Groot P, Bendik I, Schrauwen P, Goossens GH, Blaak EE Tags: Am J Clin Nutr Source Type: research

Lung Injury Combined with Loss of Regulatory T Cells Leads to De Novo Lung-Restricted Autoimmunity.
Abstract More than one third of patients with chronic lung disease undergoing lung transplantation have pre-existing Abs against lung-restricted self-Ags, collagen type V (ColV), and k-α1 tubulin (KAT). These Abs can also develop de novo after lung transplantation and mediate allograft rejection. However, the mechanisms leading to lung-restricted autoimmunity remain unknown. Because these self-Ags are normally sequestered, tissue injury is required to expose them to the immune system. We previously showed that respiratory viruses can induce apoptosis in CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs), the key med...
Source: Journal of Immunology - May 18, 2016 Category: Allergy & Immunology Authors: Chiu S, Fernandez R, Subramanian V, Sun H, DeCamp MM, Kreisel D, Perlman H, Budinger GR, Mohanakumar T, Bharat A Tags: J Immunol Source Type: research

Schoolchildren's antioxidation genotypes are susceptible factors for reduced lung function and airway inflammation caused by air pollution.
CONCLUSION: In this longitudinal study of schoolchildren. Our data provide evidence that antioxidation genotype modifies the airway inflammation caused by PM2.5. Antioxidation genotype also acts as an effect modifier, but not strong, in ozone-related small airway function response. PMID: 27208465 [PubMed - as supplied by publisher] (Source: Environmental Research)
Source: Environmental Research - May 18, 2016 Category: Environmental Health Authors: Chen BY, Chen CH, Chuang YC, Kim H, Honda Y, Chiang HC, Guo YL Tags: Environ Res Source Type: research

Syndecan-4, a PRRSV attachment factor, mediates PRRSV entry through its interaction with EGFR.
Abstract The causative agent of porcine reproductive and respiratory syndrome is the PRRS virus (PRRSV), an enveloped, single-stranded and positive-sense RNA virus. The host factors and mechanisms that are involved in PRRSV entry are still largely unknown. In our present studies, we found that syndecan-4, one of the heparan sulfate proteoglycans, plays a critical role in PRRSV entry, especially in PRRSV attachment. Moreover, EGFR interacts with syndecan-4 in MACR-145 cells and disruption of their interaction impaired PRRSV entry. Furthermore, EGFR inhibitor AG1478 or syndecan-4 derived peptide SSTN87-131 inhibited...
Source: Biochemical and Biophysical Research communications - May 18, 2016 Category: Biochemistry Authors: Wang R, Wang X, Ni B, Huan CC, Wu JQ, Wen LB, Liao Y, Tong GZ, Ding C, Fan HJ, Mao X Tags: Biochem Biophys Res Commun Source Type: research

A bitter pill for type 2 diabetes? The activation of bitter taste receptor TAS2R38 can stimulate GLP-1 release from enteroendocrine L-cells.
Abstract The bitter taste receptor TAS2R38 is a G protein coupled receptor (GPCR) that has been found in many extra-oral locations like the gastrointestinal (GI) system, respiratory system, and brain, though its function at these locations is only beginning to be understood. To probe the receptor's potential metabolic role, immunohistochemistry of human ileum tissues was performed, which showed that the receptor was co-localized with glucagon-like peptide 1 (GLP-1) in L-cells. In a previous study, we had modeled the structure of this receptor for its many taste-variant haplotypes (Tan et al. 2011), including the ta...
Source: Biochemical and Biophysical Research communications - May 18, 2016 Category: Biochemistry Authors: Pham H, Hui H, Morvaridi-Khadag S, Cai J, Zhang S, Tan J, Wu V, Levin N, Knudsen B, Goddard WA, Pandol SJ, Abrol R Tags: Biochem Biophys Res Commun Source Type: research

e-Consultation Improves Efficacy in Thoracic Surgery Outpatient Clinics.
CONCLUSIONS: The systematic regular discussion of cases using videoconferencing has a positive impact on the efficacy of the outpatient clinics of a Thoracic Surgery Service measured in terms of operated cases/first outpatient clinics visit. PMID: 27208914 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - May 18, 2016 Category: Respiratory Medicine Authors: Novoa NM, Gómez MT, Rodríguez M, Jiménez López MF, Aranda JL, Bollo de Miguel E, Diez F, Hernández Hernández J, Varela G Tags: Arch Bronconeumol Source Type: research

Sealing Effect of Cross-Linked Gelatin Glue in the Rat Lung Air Leak Model.
CONCLUSIONS: The sealing effect of gelatin glue was superior to that of fibrin glue, with or without a polyglycolic acid sheet. In addition, the gelatin glue only caused mild inflammation of the lung and was absorbed without any adverse foreign body response. These findings suggest that gelatin glue may be a therapeutically effective biomaterial for sealing lung wounds and restoring respiratory function. PMID: 27209616 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 18, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Kawai N, Suzuki S, Naito H, Kushibe K, Tojo T, Ikada Y, Taniguchi S Tags: Ann Thorac Surg Source Type: research

Descending Aortic Translocation for Relief of Distal Tracheal and Proximal Bronchial Compression.
CONCLUSIONS: A midline descending aorta can cause compression of the tracheal carina and proximal bronchi, with debilitating symptoms. Translocation of the descending aorta is a reliable procedure that relieves the compression and results in long-term resolution of symptoms. PMID: 27209610 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 18, 2016 Category: Cardiovascular & Thoracic Surgery Authors: McKenzie ED, Roeser ME, Thompson JL, De León LE, Adachi I, Heinle JS, Mery CM, Fraser CD Tags: Ann Thorac Surg Source Type: research

The Use of Hypothermic Circulatory Arrest During Heart Transplantation Does Not Worsen Posttransplant Survival.
CONCLUSIONS: The need for HCA during heart transplantation is rare but, when required, it is frequently a life-saving adjunct to cardiopulmonary bypass. However, patients who require HCA have higher rates of postoperative complications. Risk factors for needing HCA during transplantation include congenital heart disease and more than one prior sternotomies. PMID: 27209609 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 18, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Sorabella RA, Guglielmetti L, Bader A, Gomez A, Takeda K, Chai PJ, Takayama H, Bacha EA, Naka Y, George I Tags: Ann Thorac Surg Source Type: research

Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fibrosis
Conclusions: Our data indicate that the imbalance between ceramide and sphingosine in the CF respiratory tract prevents killing of S. aureus and causes the high susceptibility of CF mice to pulmonary S. aureus infections.Cell Physiol Biochem 2016;38:2094-2102 (Source: Cellular Physiology and Biochemistry)
Source: Cellular Physiology and Biochemistry - May 17, 2016 Category: Cytology Source Type: research

[Plasmodium falciparum malaria: evaluation of three imported cases].
In this report, three cases, who have admitted to our hospital with three different clinical presentations of falciparum malaria, and all shared common history of travelling to Africa were presented. First case was a 27 years old, male patient who returned from Malawi seven days ago where he stayed for two weeks. He admitted to our hospital with the complaints of sensation of cold, shivering and fever. In physical examination his body temperature was 37.9°C, C-reactive protein level was high, and the other systemic results were normal. The second case was a 25 years old, male patient who returned from Gambia two weeks ago...
Source: Mikrobiyoloji Bulteni - May 17, 2016 Category: Microbiology Tags: Mikrobiyol Bul Source Type: research

[Investigation of adenovirus isolation frequency from the stool samples of patients suspected with acute flaccid paralysis].
Authors: Bayrakdar F, Coşgun Y, Salman Atak T, Karademir H, Korukluoğlu G Abstract Although adenoviruses (AdVs) generally cause upper respiratory tract infections, conjunctivitis/epidemic keratoconjunctivitis, gastroenteritis and pneumonia, they can lead to the involvement of central nervous system. Acute flaccid paralysis (AFP) is a type of seizure, characterized by rapid and sudden onset of extreme weakness in hands and feet, including (less frequently) weakness of respiratory and swallowing, representing with decreased muscle tone, especially in children below 15-year-old. The major viral cause of AFP is polio...
Source: Mikrobiyoloji Bulteni - May 17, 2016 Category: Microbiology Tags: Mikrobiyol Bul Source Type: research

Prevalence of Anxiety and Depression in Pulmonary Hypertension and Changes during Therapy
Conclusion: Mood disorders remain underdiagnosed in PH. The higher prevalence of anxiety/depression in incident versus prevalent patients and the improvement over time may indicate an amelioration of mood disorders after PH diagnosis and treatment.Respiration (Source: Respiration)
Source: Respiration - May 17, 2016 Category: Respiratory Medicine Source Type: research

Long-Term Outcomes in Critically Ill Septic Patients Who Survived Cardiopulmonary Resuscitation*
Conclusion: The long-term outcome was worse in ICU survivors of sepsis who received in-hospital cardiopulmonary resuscitation than in those who did not, but this increased risk of mortality diminished at 2 years after discharge. (Source: Critical Care Medicine)
Source: Critical Care Medicine - May 17, 2016 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Epidemiology of Acute Respiratory Distress Syndrome Following Hematopoietic Stem Cell Transplantation*
Conclusions: Acute respiratory distress syndrome is a frequent complication following hematopoietic stem cell transplantation, dramatically influencing patient-important outcomes. Most cases of acute respiratory distress syndrome following hematopoietic stem cell transplantation do not meet criteria for a more specific post-transplantation pulmonary syndrome. These findings highlight the need to better understand the risk factors underlying acute respiratory distress syndrome in this population, thereby facilitating the development of effective prevention strategies. (Source: Critical Care Medicine)
Source: Critical Care Medicine - May 17, 2016 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

How Long Does (S)He Have? Retrospective Analysis of Outcomes After Palliative Extubation in Elderly, Chronically Critically Ill Patients
Conclusions: Palliative extubation at end of life was an option selected by an ethnically diverse elderly population. Approximately three-fourths of subjects died in hospital, and one-fourth was discharged alive. Over 50% who died did so within 24 hours, making this useful information for counseling and anticipatory planning. Subjects with systolic blood pressure less than 90 and Charlson Comorbidity Index that is very low or very high had higher mortality. (Source: Critical Care Medicine)
Source: Critical Care Medicine - May 17, 2016 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Transfusion of 35-Day Stored RBCs in the Presence of Endotoxemia Does Not Result in Lung Injury in Humans*
Conclusions: Transfusion of 35-day stored autologous RBCs in the presence of endotoxemia does not result in lung injury in humans. (Source: Critical Care Medicine)
Source: Critical Care Medicine - May 17, 2016 Category: Emergency Medicine Tags: Online Laboratory Investigations Source Type: research

Trials and Tribulations of Therapies for the Acute Respiratory Distress Syndrome
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - May 17, 2016 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Osteoectomy in Rhinoplasty: A New Concept in Nasal Bones Repositioning
Conclusions: Although this technique prolongs the operating time, it could offer considerable advantages in comparison with the classical techniques using osteotomies and hammer. This is because it offers a greater respect to the nasal respiratory function and gives a much better nasal base width control, resulting in more predictable results, less trauma, and therefore a lower risk of postoperative complications. (Source: Annals of Plastic Surgery)
Source: Annals of Plastic Surgery - May 17, 2016 Category: Cosmetic Surgery Tags: Aesthetic Surgery Source Type: research

Is The Mars Questionnaire A Reliable Measure Of Medication Adherence In Childhood Asthma?
CONCLUSIONS: Self-report using MARS-5 is too inaccurate to be a useful measure of adherence in children with asthma, both in clinical practice and in research. PMID: 27177241 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - May 17, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Transferability of genome-wide associated loci for asthma in African Americans.
CONCLUSIONS: This study has successfully transferred four reported asthma-associated loci in an independent African American population. Identification of several asthma-associated SNPs in the upstream of the IL33, a gene previously implicated in allergic inflammation of asthmatic airway, supports the generalizability of this finding. PMID: 27177148 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - May 17, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research