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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 15.

Attenuation of the pulmonary chemoreflex following acute cervical spinal cord injury
Bronchopulmonary C fibers are the primary chemosensitive afferents in the lung. The activation of bronchopulmonary C fibers evokes the pulmonary chemoreflex, which is characterized by apnea, hypotension, and bradycardia and is a critical reflex that modulates cardiorespiratory responses under physiological and pathological conditions. The present study was designed to investigate whether the pulmonary chemoreflex is altered following acute cervical spinal injury. A unilateral hemisection (Hx) or laminectomy (uninjured) in the second cervical spinal cord was performed in adult male Sprague-Dawley rats. The pulmonary chemore...
Source: Journal of Applied Physiology - April 1, 2014 Category: Physiology Authors: Tsai, I.-L., Lee, K.-Z. Tags: ARTICLES Source Type: research

Diaphragm remodeling and compensatory respiratory mechanics in a canine model of Duchenne muscular dystrophy
Ventilatory insufficiency remains the leading cause of death and late stage morbidity in Duchenne muscular dystrophy (DMD). To address critical gaps in our knowledge of the pathobiology of respiratory functional decline, we used an integrative approach to study respiratory mechanics in a translational model of DMD. In studies of individual dogs with the Golden Retriever muscular dystrophy (GRMD) mutation, we found evidence of rapidly progressive loss of ventilatory capacity in association with dramatic morphometric remodeling of the diaphragm. Within the first year of life, the mechanics of breathing at rest, and especiall...
Source: Journal of Applied Physiology - April 1, 2014 Category: Physiology Authors: Mead, A. F., Petrov, M., Malik, A. S., Mitchell, M. A., Childers, M. K., Bogan, J. R., Seidner, G., Kornegay, J. N., Stedman, H. H. Tags: ARTICLES Source Type: research

Role of chemoreception in cardiorespiratory acclimatization to, and deacclimatization from, hypoxia
During sojourn to high altitudes, progressive time-dependent increases occur in ventilation and in sympathetic nerve activity over several days, and these increases persist upon acute restoration of normoxia. We discuss evidence concerning potential mediators of these changes, including the following: 1) correction of alkalinity in cerebrospinal fluid; 2) increased sensitivity of carotid chemoreceptors; and 3) augmented translation of carotid chemoreceptor input (at the level of the central nervous system) into increased respiratory motor output via sensitization of hypoxic sensitive neurons in the central nervous system a...
Source: Journal of Applied Physiology - April 1, 2014 Category: Physiology Authors: Dempsey, J. A., Powell, F. L., Bisgard, G. E., Blain, G. M., Poulin, M. J., Smith, C. A. Tags: HIGHLIGHTED TOPIC Source Type: research

Mycobacterium avium complex infection in non‐cystic fibrosis bronchiectasis
ConclusionsChronic pulmonary aspergillosis in patients with bronchiectasis and coexisting MAC infection is a strong predictor of mortality. Cavitation within nodules and emphysema on HRCT at presentation were independently associated with mortality. (Source: Respirology)
Source: Respirology - April 1, 2014 Category: Respiratory Medicine Authors: Zaid Zoumot, Afroditi K. Boutou, Simon S. Gill, Mafalda Van Zeller, David M. Hansell, Athol U. Wells, Robert Wilson, Michael R. Loebinger Tags: Original Article Source Type: research

Intercellular adhesion molecule‐1 as a drug target in asthma and rhinitis
Abstract Intercellular adhesion molecule‐1 (ICAM‐1) is a transmembrane glycoprotein receptor of the immunoglobulin superfamily. Endothelial cells, epithelial cells, leukocytes and neutrophils are the major cells expressing ICAM‐1. Ligands of ICAM‐1 are macrophage adhesion ligand‐1, leukocyte function‐associated antigen‐1 and fibrinogen (extracellular matrix protein). In normal physiological conditions, engagement of ICAM‐1 receptor with immunological cells surface ligands assists in homing and trafficking of inflammatory cells to distant tissues. ICAM‐1 has also long been known to mediate cell‐to‐cell...
Source: Respirology - April 1, 2014 Category: Respiratory Medicine Authors: Srirupa Mukhopadhyay, Parth Malik, Sunil K. Arora, Tapan K. Mukherjee Tags: Review Source Type: research

Elevated plasma YKL‐40 as a prognostic indicator in patients with idiopathic pulmonary arterial hypertension
ConclusionsPlasma YKL‐40 might serve as a promising indicator of disease severity and prognosis in patients with IPAH. (Source: Respirology)
Source: Respirology - April 1, 2014 Category: Respiratory Medicine Authors: Guo Chen, Tao Yang, Qing Gu, Xin‐Hai Ni, Zhi‐Hui Zhao, Jue Ye, Xian‐Min Meng, Zhi‐Hong Liu, Jian‐Guo He, Chang‐Ming Xiong Tags: Original Article Source Type: research

The parable of the lobes and the fissures
(Source: Respirology)
Source: Respirology - April 1, 2014 Category: Respiratory Medicine Authors: Gregory I. Snell, Glen P. Westall Tags: Editorial Source Type: research

Survival analysis of time‐to‐event data in respiratory health research studies
This article provides a review of techniques for the analysis of survival data arising from respiratory health studies. Popular techniques such as the Kaplan–Meier survival plot and the Cox proportional hazards model are presented and illustrated using data from a lung cancer study. Advanced issues are also discussed, including parametric proportional hazards models, accelerated failure time models, time‐varying explanatory variables, simultaneous analysis of multiple types of outcome events and the restricted mean survival time, a novel measure of the effect of treatment. (Source: Respirology)
Source: Respirology - April 1, 2014 Category: Respiratory Medicine Authors: Jessica Kasza, Darren Wraith, Karen Lamb, Rory Wolfe Tags: Invited Review Series: Modern Statistical Methods in Respiratory Medicine Source Type: research

Achieving competency in bronchoscopy: Challenges and opportunities
Abstract Bronchoscopy education is undergoing significant changes in step with other medical and surgical specialties that seek to incorporate simulation‐based training and objective measurement of procedural skills into training programmes. Low‐ and high‐fidelity simulators are now available and allow learners to gain fundamental bronchoscopy skills in a zero‐risk environment. Testing trainees on simulators is currently possible by using validated assessment tools for both essential bronchoscopy and endobronchial ultrasound skills, and more tools are under development for other bronchoscopic techniques. Educationa...
Source: Respirology - April 1, 2014 Category: Respiratory Medicine Authors: David I. Fielding, Fabien Maldonado, Septimiu Murgu Tags: Invited Review Series: Update in Interventional Pulmonology Source Type: research

Laryngeal botoxification for severe asthma
(Source: Respirology)
Source: Respirology - April 1, 2014 Category: Respiratory Medicine Authors: Peter Gibson Tags: Editorial Source Type: research

Bilateral diaphragm weakness after chemotherapy for lymphoma.
PMID: 24684366 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Stevens WW, Sporn PH Tags: Am J Respir Crit Care Med Source Type: research

Reply: nonlinear weight and chronic obstructive pulmonary disease effect modeling to improve data fitting.
PMID: 24684365 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Sood A, Petersen H, Meek P, Tesfaigzi Y Tags: Am J Respir Crit Care Med Source Type: research

Nonlinear weight and chronic obstructive pulmonary disease effect modeling to improve data fitting.
PMID: 24684364 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Marin G, Molinari N, Gamez AS, Vachier I, Bourdin A Tags: Am J Respir Crit Care Med Source Type: research

The Association between Obstructive Sleep Apnea Severity and N-Terminal Pro-B-Type Natriuretic Peptide Levels in Women.
PMID: 24684363 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Lin GM Tags: Am J Respir Crit Care Med Source Type: research

Reply: The Association between Obstructive Sleep Apnea Severity and N-Terminal Pro-B-Type Natriuretic Peptide Levels in Women.
PMID: 24684362 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Querejeta Roca G, Redline S, Punjabi N, Claggett B, Ballantyne CM, Solomon SD, Shah AM Tags: Am J Respir Crit Care Med Source Type: research

Obstructive sleep apnea and preclinical cardiac damage: need for u.s. Representative study sample.
PMID: 24684361 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Mirrakhimov AE Tags: Am J Respir Crit Care Med Source Type: research

Depletion of Circulating Regulatory T Cells during Severe Respiratory Syncytial Virus Infection in Young Children.
PMID: 24684360 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Raiden S, Pandolfi J, Payasliàn F, Anderson M, Rivarola N, Ferrero F, Urtasun M, Fainboim L, Geffner J, Arruvito L Tags: Am J Respir Crit Care Med Source Type: research

Diaphragm fiber strength is reduced in critically ill patients and restored by a troponin activator.
PMID: 24684359 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Hooijman PE, Beishuizen A, de Waard MC, de Man FS, Vermeijden JW, Steenvoorde P, Bouwman RA, Lommen W, van Hees HW, Heunks LM, Dickhoff C, van der Peet DL, Girbes AR, Jasper JR, Malik FI, Stienen GJ, Hartemink KJ, Paul MA, Ottenheijm CA Tags: Am J Respir Crit Care Med Source Type: research

Mildly progressive pulmonary lymphangiectasis diagnosed in a young adult.
PMID: 24684358 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Toyoshima M, Suzuki S, Kono M, Nakamura Y, Suda T Tags: Am J Respir Crit Care Med Source Type: research

Tertiary lymphoid structures target the antitumor immune response to lung cancer.
PMID: 24684357 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Randall TD, Kern JA Tags: Am J Respir Crit Care Med Source Type: research

The burden of disease and the need for a simple staging system in idiopathic pulmonary fibrosis.
PMID: 24684356 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: O'Connell OJ, Egan JJ Tags: Am J Respir Crit Care Med Source Type: research

Cystic fibrosis transmembrane conductance regulator and pseudomonas.
PMID: 24684355 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Zemanick ET, Accurso FJ Tags: Am J Respir Crit Care Med Source Type: research

Developing a Research Agenda for Primary Prevention of Chronic Lung Diseases-An NHLBI Perspective.
PMID: 24684354 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Kiley J, Gibbons G Tags: Am J Respir Crit Care Med Source Type: research

Generalizability and Singularity. The Crossroads between Science and Clinical Practice.
PMID: 24684353 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 1, 2014 Category: Respiratory Medicine Authors: Tobin MJ Tags: Am J Respir Crit Care Med Source Type: research

Risk factors for pulmonary tuberculosis in community-acquired pneumonia.
PMID: 24687677 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 1, 2014 Category: Respiratory Medicine Authors: Cavallazzi R, Wiemken T, Ramirez J Tags: Eur Respir J Source Type: research

COPD assessment: I, II, III, IV and/or A, B, C, D.
PMID: 24687662 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 1, 2014 Category: Respiratory Medicine Authors: Vogelmeier C, Vestbo J Tags: Eur Respir J Source Type: research

The European Union standards for tuberculosis care: do they need an update?
PMID: 24687659 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 1, 2014 Category: Respiratory Medicine Authors: van der Werf MJ, Sandgren A, D'Ambrosio L, Blasi F, Migliori GB Tags: Eur Respir J Source Type: research

The European Respiratory Society plans its future: the 2013-2018 strategic plan.
PMID: 24687658 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - April 1, 2014 Category: Respiratory Medicine Authors: Migliori GB, Rabe KF, Bel E, Elliott M, Gaga M, Holgate ST, Joos G, Martin Burrieza F, Sax B, Sculier JP, Simonds AK, Blasi F, Barnes PJ Tags: Eur Respir J Source Type: research

A teenager with Fever and sore throat.
PMID: 24687725 [PubMed - in process] (Source: Chest)
Source: Chest - April 1, 2014 Category: Respiratory Medicine Authors: Cardenas-Garcia J, Narasimhan M, Koenig SJ Tags: Chest Source Type: research

Error in Title of: Detection of COPD Exacerbations and Compliance With Patient-Reported Daily Symptom Diaries.
Authors: PMID: 24687724 [PubMed - in process] (Source: Chest)
Source: Chest - April 1, 2014 Category: Respiratory Medicine Tags: Chest Source Type: research