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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 15.

Response to “MacIntyre et al., 2014: Respiratory protection for healthcare workers treating Ebola virus disease (EVD): are facemasks sufficient to meet occupational health and safety obligations?”
In response to the guest editorial recently published in your journal, “Respiratory protection for healthcare workers treating Ebola virus disease (EVD): are facemasks sufficient to meet occupational health and safety obligations?” (MacIntyre et al., 2014), I am writing to clarify an important point that the authors seem to have wilfully misunderstood when citing a letter that two colleagues and I recently published in The Lancet. (Source: International Journal of Nursing Studies)
Source: International Journal of Nursing Studies - October 13, 2014 Category: Nursing Authors: Jose M. Martin-Moreno, Gilberto Llinás, Juan Martínez-Hernández Tags: Letters Source Type: research

Effect of ezogabine retigabine on the PK of digoxin
Tompson DJ, Crean CS, Buraglio M, Arumugham T (Source: International Journal of COPD)
Source: International Journal of COPD - October 12, 2014 Category: Respiratory Medicine Source Type: research

Improving inhaler adherence in patients with chronic obstructive pulmonary disease: a cost-effectiveness analysis.
CONCLUSIONS: Optimization of current pharmacotherapy (e.g. close monitoring of inhalation technique and medication adherence) has been shown to be cost-saving and should be considered before adding new therapies. PMID: 24929799 [PubMed - indexed for MEDLINE] (Source: Respiratory Care)
Source: Respiratory Care - October 12, 2014 Category: Respiratory Medicine Authors: van Boven JF, Tommelein E, Boussery K, Mehuys E, Vegter S, Brusselle GG, Rutten-van Mölken MP, Postma MJ Tags: Respir Res Source Type: research

Impact of self-reported gastroesophageal reflux disease in subjects from COPDGene cohort.
CONCLUSIONS: In COPD the presence of physician-diagnosed GERD is associated with increased symptoms, poorer QOL and increased frequency of exacerbations at baseline and during follow-up. These associations are maintained after controlling for PPI use. The PPI-exacerbations association could result from confounding-by-indication. PMID: 24894541 [PubMed - indexed for MEDLINE] (Source: Respiratory Care)
Source: Respiratory Care - October 12, 2014 Category: Respiratory Medicine Authors: Martinez CH, Okajima Y, Murray S, Washko GR, Martinez FJ, Silverman EK, Lee JH, Regan EA, Crapo JD, Curtis JL, Hatabu H, Han MK, COPDGene Investigators Tags: Respir Res Source Type: research

Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo.
CONCLUSIONS: In summary, these data indicate that low concentrations of ATO inhibit TGF-β1-induced fibroblast to myofibroblast differentiation and decreases bleomycin induced pulmonary fibrosis. PMID: 24762191 [PubMed - indexed for MEDLINE] (Source: Respiratory Care)
Source: Respiratory Care - October 12, 2014 Category: Respiratory Medicine Authors: Luo F, Zhuang Y, Sides MD, Sanchez CG, Shan B, White ES, Lasky JA Tags: Respir Res Source Type: research

Lung ultrasound for the diagnosis of pneumonia in adults: a systematic review and meta-analysis.
CONCLUSIONS: Our meta-analysis supports that LUS, when conducted by highly-skilled sonographers, performs well for the diagnosis of pneumonia. General practitioners and Emergency Medicine physicians should be encouraged to learn LUS since it appears to be an established diagnostic tool in the hands of experienced physicians. PMID: 24758612 [PubMed - indexed for MEDLINE] (Source: Respiratory Care)
Source: Respiratory Care - October 12, 2014 Category: Respiratory Medicine Authors: Chavez MA, Shams N, Ellington LE, Naithani N, Gilman RH, Steinhoff MC, Santosham M, Black RE, Price C, Gross M, Checkley W Tags: Respir Res Source Type: research

Impact of smoking on dendritic cell phenotypes in the airway lumen of patients with COPD.
CONCLUSION: COPD is characterized by a strongly reduced CCR5 expression on myeloid DCs in the airway lumen, which might hamper DC interactions with microbial antigens. Further studies are needed to better understand the role of CCR5 in the pathophysiology and microbiology of COPD. PMID: 24742278 [PubMed - indexed for MEDLINE] (Source: Respiratory Care)
Source: Respiratory Care - October 12, 2014 Category: Respiratory Medicine Authors: Stoll P, Heinz AS, Bratke K, Bier A, Garbe K, Kuepper M, Virchow JC, Lommatzsch M Tags: Respir Res Source Type: research

Systemic steroids in COPD-the beauty and the beast.
PMID: 24708470 [PubMed - indexed for MEDLINE] (Source: Respiratory Care)
Source: Respiratory Care - October 12, 2014 Category: Respiratory Medicine Authors: Vogelmeier CF Tags: Respir Res Source Type: research

A randomized clinical trial to assess the influence of a three months training program (gym-based individualized vs. calisthenics-based non-invidualized) in COPD-patients.
CONCLUSION: A low frequency outpatient training program may induce modest improvements in exercise capacity and muscle mass only if it is performed on an individualized basis. PMID: 24666558 [PubMed - indexed for MEDLINE] (Source: Respiratory Care)
Source: Respiratory Care - October 12, 2014 Category: Respiratory Medicine Authors: Greulich T, Kehr K, Nell C, Koepke J, Haid D, Koehler U, Koehler K, Filipovic S, Kenn K, Vogelmeier C, Koczulla AR Tags: Respir Res Source Type: research

MMP-2 and TIMP-1 predict healing of WTC-lung injury in New York City firefighters.
CONCLUSIONS: Resistant cases displayed healing, returning to 99% of pre-exposure values. High TIMP-1 and MMP-2 predict healing. MMP/TIMP balance reflects independent pathways to airway injury and repair after WTC exposure. PMID: 24447332 [PubMed - indexed for MEDLINE] (Source: Respiratory Care)
Source: Respiratory Care - October 12, 2014 Category: Respiratory Medicine Authors: Nolan A, Kwon S, Cho SJ, Naveed B, Comfort AL, Prezant DJ, Rom WN, Weiden MD Tags: Respir Res Source Type: research

Exhaled breath condensate in intubated neonates--a window into the lung's glutathione status.
CONCLUSIONS: GSH status in EBC samples of intubated newborns significantly correlated with the GSH status of the TA sample and was reflective of cellular GSH status in this cohort of neonatal patients. Non-invasive EBC sampling of intubated newborns holds promise for monitoring antioxidant status such as GSH in the premature lung. Further studies are necessary to evaluate the potential relationships between EBC biomarkers in the intubated premature newborn and respiratory morbidities. PMID: 24397246 [PubMed - indexed for MEDLINE] (Source: Respiratory Care)
Source: Respiratory Care - October 12, 2014 Category: Respiratory Medicine Authors: Rosso MI, Roark S, Taylor E, Ping X, Ward JM, Roche K, McCracken C, Brown LA, Gauthier TW Tags: Respir Res Source Type: research

Intercostal and forearm muscle deoxygenation during respiratory fatigue in patients with heart failure: potential role of a respiratory muscle metaboreflex.
Abstract The purpose of this study was to determine the effect of respiratory muscle fatigue on intercostal and forearm muscle perfusion and oxygenation in patients with heart failure. Five clinically stable heart failure patients with respiratory muscle weakness (age, 66±12 years; left ventricle ejection fraction, 34±3%) and nine matched healthy controls underwent a respiratory muscle fatigue protocol, breathing against a fixed resistance at 60% of their maximal inspiratory pressure for as long as they could sustain the predetermined inspiratory pressure. Intercostal and forearm muscle blood volume and oxygenati...
Source: Braz J Med Biol Res - October 12, 2014 Category: Research Authors: Moreno AM, Castro RR, Silva BM, Villacorta H, Junior MS, Nóbrega AC Tags: Braz J Med Biol Res Source Type: research

Cigarette Smoke-Exposed Candida albicans Increased Chitin Production and Modulated Human Fibroblast Cell Responses.
Abstract The predisposition of cigarette smokers for development of respiratory and oral bacterial infections is well documented. Cigarette smoke can also contribute to yeast infection. The aim of this study was to investigate the effect of cigarette smoke condensate (CSC) on C. albicans transition, chitin content, and response to environmental stress and to examine the interaction between CSC-pretreated C. albicans and normal human gingival fibroblasts. Following exposure to CSC, C. albicans transition from blastospore to hyphal form increased. CSC-pretreated yeast cells became significantly (P < 0.01) sensitiv...
Source: Biomed Res - October 12, 2014 Category: Research Authors: Alanazi H, Semlali A, Perraud L, Chmielewski W, Zakrzewski A, Rouabhia M Tags: Biomed Res Int Source Type: research

Cost-effectiveness of initiating extrafine- or standard size-particle inhaled corticosteroid for asthma in two health-care systems: a retrospective matched cohort study.
CONCLUSIONS: Initiating ICS therapy for asthma as extrafine-particle ICS seems the dominant treatment option (less costly and more effective) compared with standard size-particle ICS in both the UK and the US. PMID: 25297072 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - October 12, 2014 Category: Primary Care Authors: Martin RJ, Price D, Roche N, Israel E, van Aalderen WM, Grigg J, Postma DS, Guilbert TW, Hillyer EV, Burden A, von Ziegenweidt J, Colice G Tags: NPJ Prim Care Respir Med Source Type: research

Respiratory medication use in an Australian developmental disability clinic population: messages for health care professionals.
This study describes respiratory medication use, reported prevalence of asthma, and asthma management practices undertaken in a clinic sample of Australian adults with ID. Results showed a prevalence of retrospectively reported asthma of 6%, with 86% of asthma patients prescribed inhaled medication. A review of patient records also indicated omission of some recommended asthma management strategies. PMID: 23693140 [PubMed - indexed for MEDLINE] (Source: Primary Care)
Source: Primary Care - October 12, 2014 Category: Primary Care Authors: Davis SR, Durvasula S, Merhi D, Young PM, Traini D, Bosnic-Anticevich SZ Tags: Aust J Prim Health Source Type: research

Comparison of innate immune agonists for induction of tracheal antimicrobial peptide gene expression in tracheal epithelial cells of cattle
Bovine respiratory disease is a complex of bacterial and viral infections of economic and welfare importance to the beef industry. Although tracheal antimicrobial peptide (TAP) has microbicidal activity against bacterial pathogens causing bovine respiratory disease, risk factors for bovine respiratory disease including BVDV and stress (glucocorticoids) have been shown to inhibit the induced expression of this gene. Lipopolysaccharide is known to stimulate TAP gene expression, but the maximum effect is only observed after 16?h of stimulation. The present study investigated other agonists of TAP gene expression in primary cu...
Source: BioMed Central - October 12, 2014 Category: Journals (General) Authors: Lesley BerghuisKhaled T AbdelazizJodi BierworthLeanna WyerGabriella JacobNiel A KarrowShayan SharifMary E ClarkJeff L Caswell Source Type: research

The association of plasma biomarkers with computed tomography-assessed emphysema phenotypes
RationaleChronic obstructive pulmonary disease (COPD) is a phenotypically heterogeneous disease. In COPD, the presence of emphysema is associated with increased mortality and risk of lung cancer. High resolution computed tomography (HRCT) scans are useful in quantifying emphysema but are associated with radiation exposure and high incidence of false positive findings (i.e., nodules). Using a comprehensive biomarker panel, we sought to determine if there was a peripheral blood biomarker signature of emphysema. Methods: 114 plasma biomarkers were measured using a custom assay in 588 individuals enrolled in the COPDGene study...
Source: Respiratory Research - October 12, 2014 Category: Respiratory Medicine Authors: Brendan CarolanGrant HughesJarrett MorrowCraig HershWanda O¿NealStephen RennardSreekumar PillaiPaula BelloniDebra CockayneAlejandro ComellasMeilan HanRachel ZemansKaterina KechrisRussell Bowler Source Type: research

The value of non-invasive ventilation
Non-invasive ventilation (NIV) use has increased markedly over the last 10 years. Children being treated with NIV are now a common sight in most paediatric intensive care units and high dependency units and nearly all tertiary respiratory units will look after a cohort of children who use NIV at home. Although the published evidence base for use of NIV in acute and chronic respiratory failure is relatively weak, it is now very unlikely that there will be any more randomised controlled trials of this intervention. Effectiveness of NIV will need to be evaluated on each child as it used. It is important to define the purpose ...
Source: Archives of Disease in Childhood - October 12, 2014 Category: Pediatrics Authors: Hull, J. Tags: Clinical trials (epidemiology) Review Source Type: research

When two trials conflict: bronchiolitis and hypertonic saline
The editors of JAMA Pediatrics must have been flummoxed when they received two papers at the same time describing the same interventional trial, with completely different results. Both were trials comparing 3% with 0.9% nebulised saline in bronchiolitis, and both were conducted in the emergency departments (EDs) of US children's hospitals. The editors took the brave decision to publish them simultaneously with an accompanying editorial. Both trials recruited infants under two years presenting to ED with a first episode of clinically diagnosed bronchiolitis, and both excluded those with pre-existing cardio-respiratory condi...
Source: Archives of Disease in Childhood - October 12, 2014 Category: Pediatrics Tags: Miscellanea Source Type: research

Towards evidence based medicine for paediatricians
More than lucky When two people/researchers/clinicians are looking at something, we often want to know if they are seeing/deciding the same thing. It has been said (but not by me, who relies on them too much) that two radiologists reviewing the same chest radiograph will have three different opinions on if there's pneumonia or not. Measuring the amount of agreement is often done using the statistic. is a measure of agreement, usually between two observers of a dichotomous outcome although there are variants for multiple observers. It gives you a measure of what agreement you see that is ‘beyond chance’ Take an ...
Source: Archives of Disease in Childhood - October 12, 2014 Category: Pediatrics Authors: Phillips, B. Tags: ADC Archimedes, Journalology, Pneumonia (infectious disease), TB and other respiratory infections, Radiology, Pneumonia (respiratory medicine), Clinical diagnostic tests, Radiology (diagnostics), Competing interests (ethics) Source Type: research

Actinotalea suaedae sp. nov., isolated from the halophyte Suaeda physophora in Xinjiang, Northwest China.
Abstract A Gram-stain-positive, aerobic, non-motile, coryneform bacterium, designated strain EGI 60002(T), was isolated from the halophyte Suaeda physophora. Cells were coryneform shaped and polymorphic. Phylogenetic analysis based on 16S rRNA gene sequences showed that the new isolate was closely related to Actinotalea ferrariae CF5-4(T) (95.8 % gene sequence similarity). The peptidoglycan type of strain EGI 60002(T) was A4β, containing L-Orn-D-Ser-D-Asp. The cell-wall sugars were mannose, ribose, rhamnose and glucose. The major fatty acids (>5 %) of strain EGI 60002(T) were iso-C14:0, iso-C15:0, anteiso-C15...
Source: Antonie van Leeuwenhoek - October 12, 2014 Category: Microbiology Authors: Zhao S, Li L, Li SH, Wang HF, Hozzein WN, Zhang YG, Wadaan MA, Li WJ, Tian CY Tags: Antonie Van Leeuwenhoek Source Type: research

Comparison of innate immune agonists for induction of tracheal antimicrobial peptide gene expression in tracheal epithelial cells of cattle
Abstract Bovine respiratory disease is a complex of bacterial and viral infections of economic and welfare importance to the beef industry. Although tracheal antimicrobial peptide (TAP) has microbicidal activity against bacterial pathogens causing bovine respiratory disease, risk factors for bovine respiratory disease including BVDV and stress (glucocorticoids) have been shown to inhibit the induced expression of this gene. Lipopolysaccharide is known to stimulate TAP gene expression, but the maximum effect is only observed after 16 h of stimulation. The present study investigated other agonists of TAP gene expr...
Source: Veterinary Research - October 12, 2014 Category: Veterinary Research Source Type: research

Drowning and immersion injury
Publication date: September 2014 Source:Anaesthesia &amp; Intensive Care Medicine, Volume 15, Issue 9 Author(s): F. Eduardo Martinez , Andrew J. Hooper Drowning is a process resulting in primary respiratory impairment from submersion/immersion in a liquid medium. It is a frequent cause of unintentional injury deaths and public health initiatives to prevent drowning are important as there are no specific interventions proven to improve outcomes in drowning victims. Risk factors for drowning include inadequate supervision, recreational or occupational access to water, risk-taking behaviour and underlying medical condit...
Source: Anaesthesia and intensive care medicine - October 12, 2014 Category: Anesthesiology Source Type: research

Pediatric Ambulatory Anesthesia
This article discusses several common preoperative dilemmas, including whether to postpone anesthesia when a child has an upper respiratory infection, whether to test young women for pregnancy, which children require overnight admission for apnea monitoring, and the effectiveness of nonpharmacological techniques for reducing anxiety. Medication issues covered include the risks of anesthetic agents in children with undiagnosed weakness, the use of remifentanil for tracheal intubation, and perioperative dosing of rectal acetaminophen. The relative merits of caudal and dorsal penile nerve block for pain after circumcision are...
Source: Anesthesiology Clinics - October 12, 2014 Category: Anesthesiology Source Type: research

Burkholderia cepacia complex isolation in non-polypoid chronic rhinosinusitis
Conclusions The novel finding of Bcc species in CRS without polyposis as well suggests that the mechanism by which these bacteria adhere to the epithelium of the upper respiratory tract may be important in the host’s colonization. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - October 12, 2014 Category: Endocrinology Source Type: research

The safety of tracheostomy speaking valve use during sleep in children: A pilot study
Conclusion This pilot study reveals that use of a tracheostomy-speaking valve during sleep, was not associated with adverse cardiopulmonary events. This is the first study to show that a tracheostomy-speaking valve might be safely used during sleep, in children. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - October 12, 2014 Category: Endocrinology Source Type: research

A case of congenital aplasia of the epiglottis in an adult
We present a case of congenital absence of the epiglottis found in a 33-year-old woman complaining of recurrent lingual tonsillitis. Laryngoscopic finding and CT scan revealed an isolated epiglottic aplasia and normal appearance of other laryngeal structure. This is the first description of physiologic evaluation in an epiglottic anomaly to find the compensatory mechanism of aspiration prevention. We discussed this case with a review of literature. (Source: American Journal of Otolaryngology)
Source: American Journal of Otolaryngology - October 12, 2014 Category: Endocrinology Source Type: research

Surveillance for respiratory health care–associated infections among inpatients in 3 Kenyan hospitals, 2010-2012
Conclusion We identified rHAIs in all ward types under surveillance in Kenyan hospitals. Viruses may have a substantial role in these infections, particularly among pediatric populations. Further research is needed to refine case definitions and understand rHAIs in ICUs. (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - October 12, 2014 Category: Infectious Diseases Source Type: research

Twitter mining for fine-grained syndromic surveillance
Conclusions Our approach yields a very high level of correlation with flu trends derived from traditional surveillance systems. Compared with Google Flu, another popular tool based on query search volumes, our method is more flexible and less sensitive to changes in web search behaviors. (Source: Artificial Intelligence in Medicine)
Source: Artificial Intelligence in Medicine - October 12, 2014 Category: Bioinformatics Source Type: research

0209: Monoamine oxidases as novel sources of reactive oxygen species in experimental diabetes
In conclusion, MAO-derived ROS contribute to endothelial dysfunction in the diabetic rat. Further experiments are required to assess the mechanisms underlying MAO-dependent H2O2 formation. This work was supported by the university grant for young researchers, project code PII-C2-TC-2014 (Source: Archives of Cardiovascular Diseases Supplements)
Source: Archives of Cardiovascular Diseases Supplements - October 12, 2014 Category: Cardiology Source Type: research

Internal contamination with leech in a turkey
Publication date: February 2015 Source:Asian Pacific Journal of Tropical Disease, Volume 5, Issue 2 Author(s): Mahmoud Bahmani , Majid Gholami-Ahangaran , Fereidoun Ghotbian , Hassan Hassanzadazar , Seyed Ahmad Karamati , Reza Sepahvand , Ayoub Darabi Leech enters to mouth and nose through water. Nose and nasopharynx mucosa are the most preferred places for leech attachment with epistaxis and respiratory distress symptoms. But the leeches may rarely stick deeper to trachea or esophagus which could cause hematemesis, hemoptysis and severe respiratory distress. Leech infestation can cause gastrointestinal, respiratory and ...
Source: Asian Pacific Journal of Tropical Disease - October 12, 2014 Category: Tropical Medicine Source Type: research

Evaluation of antimicrobial study in in vitro application of Clerodendrum infortunatum Linn.
Conclusions The findings evidently appear promising antibacterial and antifungal properties of Clerodendrum infortunatum against antagonistic pathogens. Leaf possesses quite potent activity than root and stem specially leaf extract&gt;root extract&gt;stem extract. This study serves as basis for further research to lead compounds to be isolated so that it may be as a template for the implications of these results for bioactivity and drug discovery potential of herbal products. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - October 12, 2014 Category: Tropical Medicine Source Type: research

Molecular detection of the carriers of Staphylococcus aureus golden in referred to the Imam Ali Clinic in Shahrekord, Iran
Conclusions The results of the present study showed that the frequency of the S. aureus strain isolated from the nasal swabs of patients with respiratory tract infections admitted to the Imam Ali Clinic in Shahrekord, Iran, was remarkable. Thus, knowing detection of S. aureus carriers, who are at a risk of spreading nosocomial infection among the staff, is vital to control and prevent nosocomial infections. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - October 12, 2014 Category: Tropical Medicine Source Type: research

Delivery systems for siRNA drug development in cancer therapy
Publication date: Available online 28 August 2014 Source:Asian Journal of Pharmaceutical Sciences Author(s): Cong-fei Xu , Jun Wang Since the discovery of the Nobel prize-winning mechanism of RNA interference (RNAi) ten years ago, it has become a promising drug target for the treatment of multiple diseases, including cancer. There have already been some successful applications of siRNA drugs in the treatment of age-related macular degeneration and respiratory syncytial virus infection. However, significant barriers still exist on the road to clinical applications of siRNA drugs, including poor cellular uptake, instabilit...
Source: Asian Journal of Pharmaceutical Sciences - October 12, 2014 Category: Drugs & Pharmacology Source Type: research

Chronic obstructive pulmonary disease: Emergency care in acute exacerbation
Publication date: Available online 20 August 2014 Source:African Journal of Emergency Medicine Author(s): Tedd J. Welniak , Amy Panzenbeck , Alex Koyfman , Mark Foran Chronic obstructive pulmonary disease (COPD) is a preventable condition affecting more than 230 million people globally, and is expected to become the world’s third largest cause of mortality by 2030. Despite this fact, it is thought to be widely underdiagnosed and underreported across the African continent. This presents a challenge to emergency medicine (EM) providers in the region, who are faced with treating large numbers of patients presenting with e...
Source: African Journal of Emergency Medicine - October 12, 2014 Category: Emergency Medicine Source Type: research

Assessment of knowledge and skills of triage amongst nurses working in the emergency centres in Dar es Salaam, Tanzania
Discussion Nurses who participated in this study demonstrated significant deficits in knowledge and skills regarding patients’ triaging in the EC. To correct these deficits, immediate in-service training/education workshops should be carried out, followed by continuous professional development on a regular basis, including refresher training, supportive supervision and clinical skills sessions. (Source: African Journal of Emergency Medicine)
Source: African Journal of Emergency Medicine - October 12, 2014 Category: Emergency Medicine Source Type: research

Isolated dysphagia unmasking bulbar neurosarcoidosis and pulmonary sarcoidosis
We report a 54year old female presenting with a six month history of worsening dysphagia. She denied respiratory symptoms. Physical exam was normal. ESR was 61mm/hr. Serum ACE level was 65mcg/L. Chest X-ray was normal. Esophagram revealed a large amount of contrast pooling in pharyngeal recesses with intermittent laryngeal aspiration. Swallow videofluorography showed a decreased retraction of the base of the tongue, limited laryngeal elevation, and a large amount of contrast pooling in pharyngeal recesses with intermittent laryngeal aspiration. EGD showed a normal opening of the upper esophageal sphincter and the cricophar...
Source: Arab Journal of Gastroenterology - October 12, 2014 Category: Gastroenterology Source Type: research

Legalizing Cannabis: A physician’s primer on the pulmonary effects of marijuana
Abstract Habitual smoking of marijuana is associated with multiple respiratory symptoms such as cough, sputum production, and wheezing .These symptoms are not significantly different from those exhibited by tobacco smokers. Furthermore, endobronchial biopsies of habitual smokers of marijuana and /or tobacco have shown that both marijuana and cigarette smoking cause significant bronchial mucosal histopathology and that these effects are additive. Although marijuana smokers have minimal changes in pulmonary function studies as compared to tobacco smokers, they may develop bullous disease and spontaneous pneumothorac...
Source: Current Respiratory Care Reports - October 11, 2014 Category: Respiratory Medicine Source Type: research

Virologic testing in bronchiolitis: does it change management decisions and predict outcomes?
Conclusion: Although RSV bronchiolitis has a more severe clinical course, virologic testing does not help in management decisions, and at an individual level, as a performance test, it seems insufficient to precisely predict outcomes. (Source: European Journal of Pediatrics)
Source: European Journal of Pediatrics - October 11, 2014 Category: Pediatrics Source Type: research