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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 16.

Open lung biopsy in nonresolving ARDS frequently identifies diffuse alveolar damage regardless of the severity stage and may have implications for patient management
Conclusions DAD is present in the majority of patients with nonresolving ARDs and its frequency is no different across the three ARDS stages. On this basis, the systematic use of steroids in nonresolving ARDS is not recommended. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - December 5, 2014 Category: Intensive Care Source Type: research

Drug-induced anaphylactic reactions in Indian population: A systematic review
Conclusion: Antimicrobials, NSAIDs, and neuromuscular blockers are common causative groups. The most fatal cases can be prevented by avoiding allergen drugs. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - December 5, 2014 Category: Intensive Care Authors: Tejas K PatelParvati B PatelManish J BarvaliyaCB Tripathi Source Type: research

Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1α independent proliferation
In conclusion, loss of peroxisomal metabolism in hepatocytes perturbs the mitochondrial inner membrane, depletes mitochondrial DNA and causes mitochondrial biogenesis independent of PGC-1α. (Source: Biochimica et Biophysica Acta (BBA) Molecular Cell Research)
Source: Biochimica et Biophysica Acta (BBA) Molecular Cell Research - December 5, 2014 Category: Molecular Biology Source Type: research

Extracorporeal CO2 removal as bridge to lung transplantation in life‐threatening hypercapnia
We report on 20 patients with life‐threatening hypercapnia who received extracorporeal CO2 removal (ECCO2‐R) by means of the interventional lung assist (ILA®, Novalung) as bridge to LTX. The most common underlying diagnoses were bronchiolitis obliterans syndrome, cystic fibrosis, and idiopathic pulmonary fibrosis, respectively. The type of ILA was pumpless arteriovenous or pump‐driven venovenous (ILA activve®, Novalung) in 10 patients each. ILA bridging was initiated in 15 invasively ventilated and five noninvasively ventilated patients, of whom one had to be intubated prior to LTX. Hypercapnia and acidosis were ef...
Source: Transplant International - December 5, 2014 Category: Transplant Surgery Authors: Peter Schellongowski, Katharina Riss, Thomas Staudinger, Roman Ullrich, Claus G. Krenn, Christian Sitzwohl, Andja Bojic, Philipp Wohlfarth, Wolfgang R. Sperr, Werner Rabitsch, Clemens Aigner, Shahrokh Taghavi, Peter Jaksch, Walter Klepetko, György Lang Tags: Original Article Source Type: research

Head and neck teratoma: From diagnosis to treatment
Conclusion Early prenatal diagnosis is crucial to neonatal care. Early surgery and meticulous follow-up are critical in the long-term favourable outcome. (Source: Journal of Cranio Maxillofacial Surgery)
Source: Journal of Cranio Maxillofacial Surgery - December 5, 2014 Category: ENT & OMF Source Type: research

Different therapeutic mechanisms of rigid and semi-rigid mandibular repositioning devices in obstructive sleep apnea syndrome
In conclusion, both types of MRDs improve respiratory status, but they affect different parts of the airway. (Source: Journal of Cranio Maxillofacial Surgery)
Source: Journal of Cranio Maxillofacial Surgery - December 5, 2014 Category: ENT & OMF Source Type: research

Retrospective analysis of demographic and clinical factors associated with etiology of febrile respiratory illness among US military basic trainees
Conclusions: Specific demographic and clinical factors were associated with laboratory-confirmed influenza and adenovirus among military trainees. Findings from this study can guide clinicians in the diagnosis and treatment of military trainees presenting with FRI. (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - December 5, 2014 Category: Infectious Diseases Authors: Damaris PadinDennis FaixStephanie BrodineHector LemusAnthony HawksworthShannon PutnamPatrick Blair Source Type: research

Is inflammatory chronic obstructive pulmonary disease a coronary heart disease risk equivalent? A longitudinal analysis of the third National Health and Nutrition Examination Survey (NHANES III), 1988-1994
Conclusions: Our study did not confirm that inflammatory COPD may be a CHD risk equivalent. However, due to the small size of the "inflammatory" COPD group, further prospective replication and validation is needed. Moreover, given that COPD results from inflammation, the systemic inflammation associated with COPD may have worsened comorbid conditions and may have lead to the increased total mortality found in the COPD with inflammation and COPD + CHD groups which requires further investigation. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 5, 2014 Category: Respiratory Medicine Authors: Donna ParkerJonathan LiuMary RobertsCharles Eaton Source Type: research

Cystic fibrosis (CF) care through the patients’ eyes – a nationwide survey on experience and satisfaction with services using a disease-specific questionnaire
The patients´ perspective is an important aspect of quality management. A newly developed disease-specific questionnaire was used to assess the patients´ experiences with care provided in specialised cystic fibrosis (CF) care centres. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 5, 2014 Category: Respiratory Medicine Authors: Gratiana Steinkamp, Katja Stahl, Helmut Ellemunter, Eberhard Heuer, Silke van Koningsbruggen-Rietschel, Melanie Busche, Wilhelm Bremer, Carsten Schwarz, for the Patient Experience Working Group Source Type: research

Strategies for managing oxygenation in obese patients undergoing laparoscopic surgery
The worldwide trend toward increasing body mass index (BMI) has caused the anesthetic management of overweight, obese and severely obese patients to become common. The increase in oxygen demand coupled with the anatomical and physiological changes associated with excess adipose tissue make maintenance of oxygenation a major challenge during induction, maintenance and recovery from general anesthesia. It is crucial for anesthesiologists, surgeons and perioperative health care providers alike to have a thorough understanding of the impact of airway management and mechanical ventilation on the respiratory care of the obese in...
Source: Surgery for Obesity and Related Diseases - December 5, 2014 Category: Surgery Authors: Vilma E. Ortiz, Marcos F. Vidal-Melo, John L. Walsh Source Type: research

Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing cesarean delivery.
CONCLUSIONS: Based on high quality evidence from studies whose overall risk of bias is low, intravenous prophylactic antibiotics for cesarean administered preoperatively significantly decreases the incidence of composite maternal postpartum infectious morbidity as compared with administration after cord clamp. There were no clear differences in adverse neonatal outcomes reported. Women undergoing cesarean delivery should receive antibiotic prophylaxis preoperatively to reduce maternal infectious morbidities. Further research may be needed to elucidate short- and long-term adverse effects for neonates. PMID: 25479008 [P...
Source: Cochrane Database of Systematic Reviews - December 5, 2014 Category: Journals (General) Authors: Mackeen AD, Packard RE, Ota E, Berghella V, Baxter JK Tags: Cochrane Database Syst Rev Source Type: research

The Cardiac Protein Alpha-T-catenin Contributes to Chemical-induced Asthma.
Abstract 10-25% of adult asthma is occupational-induced, a subtype caused by exposure to workplace chemicals. A recent genome-wide association study identified single nucleotide polymorphisms in the cardiac protein αT-catenin (αT-cat) that correlated with the incidence and severity of toluene diisocyanate (TDI) occupational asthma. αT-cat is a critical mediator of cell-cell adhesion and is predominantly expressed in cardiomyocytes, but its connection to asthma remains unknown. Therefore, we sought to determine the primary αT-cat-expressing cell type in the lung and its contribution to lung physiology in a murin...
Source: Am J Physiol Lung Ce... - December 5, 2014 Category: Respiratory Medicine Authors: Folmsbee SS, Morales-Nebreda L, Van Hengel J, Tyberghein K, Van Roy F, Budinger GS, Bryce PJ, Gottardi CJ Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Differential and Opposing Effects of Imatinib on LPS- and Ventilator-Induced Lung Injury.
Abstract Endothelial dysfunction underlies the pathophysiology of vascular disorders such as acute lung injury (ALI) syndromes. Recent work has identified the Abl family kinases (c-Abl and Arg) as important regulators of endothelial cell (EC) barrier function and suggests that their inhibition by currently available pharmaceutical agents such as imatinib may be EC protective. Here we describe novel and differential effects of imatinib in regulating lung pathophysiology in two clinically-relevant experimental models of ALI. Imatinib attenuates endotoxin (LPS)-induced vascular leak and lung inflammation in mice, but ...
Source: Am J Physiol Lung Ce... - December 5, 2014 Category: Respiratory Medicine Authors: Letsiou E, Rizzo AN, Sammani S, Naureckas P, Jacobson JR, Garcia JG, Dudek SM Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

ADAM-family metalloproteinases in lung inflammation - potential therapeutic targets.
Abstract Acute and chronic lung inflammation are driven and controlled by several endogenous mediators that undergo proteolytic conversion from surface expressed proteins to soluble variants by a disintegrin and metalloproteinase (ADAM) family members. TNF and epidermal growth factor receptor ligands are just some of the many substrates by which these proteases regulate inflammatory or regenerative processes in the lung. ADAM10 and ADAM17 are the most prominent members of this protease family. They are constitutively expressed in most lung cells and - as recent research has shown - are the pivotal shedding enzymes ...
Source: Am J Physiol Lung Ce... - December 5, 2014 Category: Respiratory Medicine Authors: Dreymueller D, Uhlig S, Ludwig A Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Plasma vascular endothelial growth factor A and placental growth factor: novel biomarkers of pulmonary hypertension in congenital diaphragmatic hernia.
Abstract Pulmonary hypertension (PH) due to abnormal pulmonary vascular development is an important determinant of illness severity in congenital diaphragmatic hernia (CDH). Vascular endothelial growth factor A (VEGFA) and placental growth factor (PLGF) may be important mediators of pulmonary vascular development in health and disease. This prospective study investigated the relationship between plasma VEGFA and PLGF and measures of pulmonary artery pressure, oxygenation and cardiac function and in CDH. A cohort of ten infants with CDH consecutively admitted to a surgical neonatal intensive care unit (NICU) was rec...
Source: Am J Physiol Lung Ce... - December 5, 2014 Category: Respiratory Medicine Authors: Patel N, Moenkemeyer F, Germano S, Cheung MM Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Hypoxia-induced Glucose-6-Phosphate Dehydrogenase Over-Expression and -Activation in Pulmonary Artery Smooth Muscle Cells: Implication in Pulmonary Hypertension.
Abstract Severe pulmonary hypertension is a debilitating disease with an alarmingly low 5-year life expectancy. Hypoxia, one of the causes of pulmonary hypertension, elicits constriction and remodeling of the pulmonary arteries. We now know that pulmonary arterial remodeling is a consequence of hyperplasia and hypertrophy of pulmonary artery smooth muscle (PASM), endothelial, myofibroblast, and stem cells. However, our knowledge about the mechanisms that cause these cells to proliferate and hypertrophy in response to hypoxic stimuli is still incomplete and, hence, the treatment for severe pulmonary arterial hyperte...
Source: Am J Physiol Lung Ce... - December 5, 2014 Category: Respiratory Medicine Authors: Chettimada S, Gupte R, Rawat D, Gebb SA, McMurtry IF, Gupte SA Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Relaxant effect of superimposed length oscillation on sensitized airway smooth muscle.
This study investigates the effect of length oscillations (LO), with amplitude 1% and 1.5% in the frequency range 5-20 Hz superimposed on breathing equivalent LO, on contracted ASM dissected from sensitized mice. These mice are believed to show some symptoms such as airway hyperreactivity (AH) similar to those associated with asthma in humans. In the frequency range used in this work, this study shows an increase in ASM relaxation of an average of 10% for 1.5% amplitude when compared with TO, ISO or the combination of both. No similar finding is observed with 1% amplitude. This suggests that superimposed length oscillation...
Source: Am J Physiol Lung Ce... - December 5, 2014 Category: Respiratory Medicine Authors: Jo-Avila M, Al-Jumaily AM, Lu J Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

LGL1 modulates proliferation, apoptosis and migration of human fetal lung fibroblasts.
Abstract Rapid growth and formation of new gas exchange units (alveogenesis) are hallmarks of the perinatal lung. Bronchopulmonary dysplasia (BPD), common in very premature infants, is characterized by premature arrest of alveogenesis. Mesenchymal cells (fibroblasts) regulate both lung branching and alveogenesis through mesenchymal - epithelial interactions. Temporal or spatial deficiency of late gestation lung 1 (LGL1/CRISPLD2), expressed in and secreted by lung fibroblasts, can impair both lung branching and alveogenesis. Absence of Lgl1 is embryonic lethal. Lgl1 levels are dramatically reduced in oxygen toxicity...
Source: Am J Physiol Lung Ce... - December 5, 2014 Category: Respiratory Medicine Authors: Zhang H, Sweezey NB, Kaplan F Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

L-Thyroxine promotes a proliferative airway smooth muscle phenotype in the presence of TGF-β1.
Abstract Hypothyroidism may reduce, whereas hyperthyroidism may aggravate asthma symptoms. The mechanisms underlying this relationship are largely unknown. Since thyroid hormones have central roles in cell growth and differentiation, we hypothesized that airway remodeling, in particular increased airway smooth muscle (ASM) mass, may be involved. To address this hypothesis, we investigated the effects of triiodothyronine (T3) and L-thyroxine (T4) in the absence and presence of the profibrotic transforming growth factor (TGF)-β1 on human ASM cell phenotype switching. T3 (1-100 nM) and T4 (1-100 nM) did not affect ba...
Source: Am J Physiol Lung Ce... - December 5, 2014 Category: Respiratory Medicine Authors: Dekkers BG, Naeimi S, Bos IS, Menzen MH, Halayko AJ, Sadeghi Hashjin G, Meurs H Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Diabetes-Related Mortality in Adults with Cystic Fibrosis: Role of Genotype and Gender.
Conclusions Despite substantial improvement over time, mortality for CFRD patients >30 years remains higher than for CF patients without diabetes. PMID: 25479583 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - December 5, 2014 Category: Respiratory Medicine Authors: Lewis C, Blackman SM, Nelson A, Oberdorfer E, Wells D, Dunitz J, Thomas W, Moran A Tags: Am J Respir Crit Care Med Source Type: research

Who Cares About Preventing ARDS?
Abstract ARDS is a common, lethal, and morbid respiratory complication primarily seen in the setting of major trauma and infection. Despite advances in mechanical ventilation for ARDS, many interventions have not been successful in reducing mortality. Recent grant announcements and ongoing clinical trials indicate an interest in preventing ARDS. This Perspective challenges some of the basic assumptions of ARDS prevention and preventive care in the ICU. ARDS is an organ function surrogate outcome. Studies of surrogate outcomes in medicine have repeatedly failed to show an association with patient centered outcomes t...
Source: American Journal of Respiratory and Critical Care Medicine - December 5, 2014 Category: Respiratory Medicine Authors: Rubenfeld GD Tags: Am J Respir Crit Care Med Source Type: research

Timing of Low Tidal Volume Ventilation and ICU Mortality in ARDS: A Prospective Cohort Study.
Conclusions: Higher tidal volumes shortly after ARDS onset were associated with a greater risk of ICU mortality compared to subsequent tidal volumes. Timely recognition of ARDS and adherence to low tidal volume ventilation is important for reducing mortality. Clinicaltrials.gov NCT00300248. PMID: 25478681 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - December 5, 2014 Category: Respiratory Medicine Authors: Needham DM, Yang T, Dinglas VD, Mendez-Tellez PA, Shanholtz C, Sevransky JE, Brower RG, Pronovost PJ, Colantuoni E Tags: Am J Respir Crit Care Med Source Type: research

Does the 6-minute walk test predict nocturnal oxygen desaturation in patients with moderate to severe COPD?
Abstract Patients with chronic obstructive pulmonary disease (COPD) who have nocturnal oxygen desaturation (NOD) can be treated with nocturnal oxygen therapy (NOT) to avoid possible morbidity and mortality. Although there is no definite data recommending NOT alone, our aim is to evaluate the relationship between desaturation during the six-minute walk test (6MWT) and NOD in COPD. Fifty-five stable patients with COPD were enrolled in this study. The 6MWT and nocturnal oximetry were performed. Patients with comorbid diseases and respiratory failure were excluded. In total, 55 patients (49 males and 6 females, mean ag...
Source: Chronic Respiratory Disease - December 5, 2014 Category: Respiratory Medicine Authors: Iliaz S, Cagatay T, Bingol Z, Okumus G, Iliaz R, Kuran G, Kiyan E, Cagatay P Tags: Chron Respir Dis Source Type: research

Pathological changes in a patient with acute respiratory distress syndrome and H7N9 influenza virus infection
No abstract (Source: Critical Care)
Source: Critical Care - December 5, 2014 Category: Intensive Care Authors: Qiang GuoJian-an HuangDaguo ZhaoJun JinShenlang LiuDustin Fraidenburg Source Type: research

Respiratory syncytial virus - United States, july 2012-june 2014.
Abstract Respiratory syncytial virus (RSV) causes lower respiratory infection among infants and young children worldwide. Annually in the United States, RSV infection has been associated with an estimated 57,527 hospitalizations and 2.1 million outpatient visits among children aged <5 years. In temperate climate zones, RSV generally circulates during the fall, winter, and spring. However, the exact timing and duration of RSV seasons vary by region and from year-to-year. Knowing the start of the RSV season in any given locality is important to health care providers and public health officials who use RSV seasonal...
Source: MMWR Morb Mortal Wkl... - December 5, 2014 Category: Epidemiology Authors: Haynes AK, Prill MM, Iwane MK, Gerber SI Tags: MMWR Morb Mortal Wkly Rep Source Type: research

Early Right Ventricular Fibrosis and Reduction in Biventricular Cardiac Reserve in the Dystrophin-Deficient mdx Heart.
Abstract Duchenne muscular dystrophy (DMD) is a progressive disease of striated muscle deterioration. Respiratory and cardiac muscle dysfunction are particularly clinically relevant because they result in the leading causes of death in DMD patients. Despite the clinical and physiological significance of these systems, little has been done to understand the cardio-respiratory interaction in DMD. We show here that prior to the onset of global cardiac dysfunction, dystrophin-deficient mdx mice have increased cardiac fibrosis with the right ventricle being particularly affected. Using a novel biventricular cardiac cath...
Source: American Journal of Physiology. Heart and Circulatory Physiology - December 5, 2014 Category: Physiology Authors: Meyers TA, Townsend D Tags: Am J Physiol Heart Circ Physiol Source Type: research

Cystic fibrosis (CF) care through the patients' eyes – A nationwide survey on experience and satisfaction with services using a disease-specific questionnaire
The patients' perspective is an important aspect of quality management. A newly developed disease-specific questionnaire was used to assess the patients' experiences with care provided in specialised cystic fibrosis (CF) care centres. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - December 5, 2014 Category: Respiratory Medicine Authors: Gratiana Steinkamp, Katja Stahl, Helmut Ellemunter, Eberhard Heuer, Silke van Koningsbruggen-Rietschel, Melanie Busche, Wilhelm Bremer, Carsten Schwarz, for the Patient Experience Working Group Source Type: research

[Measurement of CO diffusion capacity (II): Standardization and quality criteria.]
Abstract The diffusion capacity is the technique that measures the ability of the respiratory system for gas exchange, thus allowing a diagnosis of the malfunction of the alveolar-capillary unit. The most important parameter to assess is the CO diffusion capacity (DLCO). New methods are currently being used to measure the diffusion using nitric oxide (NO). There are other methods for measuring diffusion, although in this article the single breath technique is mainly referred to, as it is the most widely used and best standardized. Its complexity, its reference equations, differences in equipment, inter-patient vari...
Source: Anales de Pediatria - December 5, 2014 Category: Pediatrics Authors: Salcedo Posadas A, Villa Asensi JR, de Mir Messa I, Sardón Prado O, Larramona H Tags: An Pediatr (Barc) Source Type: research

A Bayesian spatio¿temporal approach for real¿time detection of disease outbreaks: a case study
Conclusions: The advantages of our methodology for addressing the complicated issues of real world surveillance data applications are three‐fold. We can easily incorporate additional covariate information and spatio‐temporal dynamics in the data. Second, we furnish a unified framework to provide uncertainties associated with each parameter. Third, we are able to handle multiplicity issues by using a Bayesian approach. The urgent need to quickly and effectively monitor the health of the public makes our methodology a potentially plausible and useful surveillance approach for health professionals. (Source: BMC Medical In...
Source: BMC Medical Informatics and Decision Making - December 5, 2014 Category: Information Technology Authors: Jian ZouAlan KarrGauri DattaJames LynchShaun Grannis Source Type: research

Microbicidal activity of neutrophils is inhibited by isolates from recurrent vaginal candidiasis (RVVC) caused by Candida albicans through fungal thioredoxin reductase.
Abstract Vulvovaginal candidiasis (VVC) is characterized by an infection of the vulva and vagina, mainly caused by Candida albicans, a commensal microorganism that inhabits the vaginal, digestive, and respiratory mucosae. Vulvovaginal candidiasis affects approximately 75% of women, and 5% develop the recurrent form (RVVC). The aim of the present study was to evaluate whether neutrophils microbicidal response is triggered when activated with RVVC isolates caused by C. albicans. Our results showed that RVVC isolates induced neutrophil migration but significantly decrease the microbicidal activity of neutrophils, comp...
Source: Cellular Immunology - December 5, 2014 Category: Allergy & Immunology Authors: Ratti BA, Godoy JS, de Souza Bonfim Mendonça P, Bidóia DL, Nakamura TU, Nakamura CV, Lopes Consolaro ME, Estivalet Svidzinski TI, de Oliveira Silva S Tags: Cell Immunol Source Type: research

Impact of bypass flow rate and catheter position in veno-venous extracorporeal membrane oxygenation on gas exchange in vivo
In conclusion, the best return cannula position was the SVC, and a high bypass flow rate was advantageous for effective oxygenation. Both the bypass flow rates and cannula position must be considered to achieve effective oxygenation. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - December 4, 2014 Category: Transplant Surgery Source Type: research

Alpha-1 antitrypsin deficiency-associated chronic obstructive pulmonary disease: a family perspective
COPD: Journal of Chronic Obstructive Pulmonary Disease, Ahead of Print. (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - December 4, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Breathlessness or Health Status in Chronic Obstructive Pulmonary Disease: The Impact of Different Definitions
COPD: Journal of Chronic Obstructive Pulmonary Disease, Ahead of Print. (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - December 4, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Prevalence, Risk Factors and Diagnostic Accuracy of COPD Among Smokers in Primary Care
COPD: Journal of Chronic Obstructive Pulmonary Disease, Ahead of Print. (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - December 4, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Optimization of Potent and Selective Quinazolinediones: Inhibitors of Respiratory Syncytial Virus That Block RNA-Dependent RNA-Polymerase Complex Activity
Journal of Medicinal ChemistryDOI: 10.1021/jm500902x (Source: Journal of Medicinal Chemistry)
Source: Journal of Medicinal Chemistry - December 4, 2014 Category: Chemistry Authors: Daljit S. Matharu, Daniel P. Flaherty, Denise S. Simpson, Chad E. Schroeder, Donghoon Chung, Dan Yan, James W. Noah, Colleen B. Jonsson, E. Lucile White, Jeffrey Aubé, Richard K. Plemper, William E. Severson and Jennifer E. Golden Source Type: research

Evaluation of Minnesota and Illinois Hospital Respiratory Protection Programs and Health Care Worker Respirator Use
(Source: Journal of Occupational and Environmental Hygiene)
Source: Journal of Occupational and Environmental Hygiene - December 4, 2014 Category: Occupational Health Authors: Brosseau, Lisa M.Conroy, Lorraine M.Sietsema, MargaretCline, KariDurski, Kara Source Type: research

Epidemics of asbestos-related diseases – something old, something new
At the beginning of the 21st century, the world is still confronted with some well-recognized major occupational and environmental health hazards, such as the continuing use of asbestos fibers in various industrial products and processes. This in spite of authoritative statements from UN bodies (the World Health Organization, the International Labor Organization, and the UN Environment Program) and various NGO (1). These organizations have called on countries throughout the world to eliminate asbestos-related diseases. They point to the great potential for prevention through banning new applications of asbestos and availin...
Source: Scandinavian Journal of Work, Environment and Health - December 4, 2014 Category: Occupational Health Tags: Editorial Source Type: research

Endoscopic Lung Volume Reduction with Endobronchial Valves in Patients with Severe Emphysema and Established Pulmonary Hypertension
Conclusion: To our knowledge, this is the first prospective, single-center pilot study to evaluate the feasibility and efficacy of ELVR in patients with established PH. ELVR was feasible and resulted in an improvement of clinical and hemodynamic parameters in 5 out of 6 patients. These results have to be further confirmed in larger-scale controlled studies.Respiration (Source: Respiration)
Source: Respiration - December 4, 2014 Category: Respiratory Medicine Source Type: research

Considerations in deriving quantitative cancer criteria for inorganic arsenic exposure via inhalation.
Abstract The inhalation unit risk (IUR) that currently exists in the United States Environmental Protection Agency's (US EPA's) Integrated Risk Information System was developed in 1984 based on studies examining the relationship between respiratory cancer and arsenic exposure in copper smelters from two US locations: the copper smelter in Anaconda, Montana, and the American Smelting And Refining COmpany (ASARCO) smelter in Tacoma, Washington. Since US EPA last conducted its assessment, additional data have become available from epidemiology and mechanistic studies. In addition, the California Air Resources Board, T...
Source: Environment International - December 4, 2014 Category: Environmental Health Authors: Lewis AS, Beyer LA, Zu K Tags: Environ Int Source Type: research

The safety of ethambutol dihydrochloride dry powder formulations containing chitosan for the possibility of treating lung tuberculosis
Inhalation Toxicology, Volume 26, Issue 14, Page 908-917, December 2014. (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - December 4, 2014 Category: Respiratory Medicine Tags: article Source Type: research

A dynamic smoke generation and nose-only inhalation exposure system for rats: preliminary results from studies of selected transportation materials
Inhalation Toxicology, Volume 26, Issue 14, Page 897-907, December 2014. (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - December 4, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Respiratory symptoms, lung function decrement and chronic obstructive pulmonary disease in pre-menopausal Indian women exposed to biomass smoke
Inhalation Toxicology, Volume 26, Issue 14, Page 866-872, December 2014. (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - December 4, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Ultrafine carbon black attenuates the antihypertensive effect of captopril in spontaneously hypertensive rats
Inhalation Toxicology, Volume 26, Issue 14, Page 853-860, December 2014. (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - December 4, 2014 Category: Respiratory Medicine Tags: article Source Type: research