Respiratory Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 16.
Respiratory deficits in a rat model of Parkinson’s disease
Publication date: 25 June 2015 Source:Neuroscience, Volume 297 Author(s): M. Tuppy , B.F. Barna , L. Alves-dos-Santos , L.R.G. Britto , S. Chiavegatto , T.S. Moreira , A.C. Takakura Parkinson’s disease (PD) is a neurodegenerative disease characterized by loss of the dopaminergic nigrostriatal pathway. In addition to deficits in voluntary movement, PD involves a disturbance of breathing regulation. However, the cause and nature of this disturbance are not well understood. Here, we investigated breathing at rest and in response to hypercapnia (7% CO2) or hypoxia (8% O2), as well as neuroanatomical changes in brainstem re...
Source: Neuroscience - April 20, 2015 Category: Neuroscience Source Type: research
Early‐life house dust mite allergens, childhood mite sensitization, and respiratory outcomes
ConclusionOur study based on geographically spread regions, a large sample size, and a wide range of allergen concentration shows that HDM allergen concentrations vary across regions and that exposure during early life plays a role in the development of allergic sensitization but not in the development of respiratory outcomes. (Source: Allergy)
Source: Allergy - April 20, 2015 Category: Allergy & Immunology Authors: L. Casas, J. Sunyer, C. Tischer, U. Gehring, M. Wickman, R. Garcia‐Esteban, I. Lehmann, I. Kull, A. Reich, S. Lau, A. Wijga, J. M. Antó, T. S. Nawrot, J. Heinrich, T. Keil, M. Torrent Tags: Original Article Source Type: research
Multidisciplinary management of locally advanced and widely metastatic paraganglioma in a patient with life‐threatening compressive symptoms
Conclusions: Although the currently available treatment options for patients with advanced metastatic paraganglioma render no survival benefit, a multidisciplinary management approach aimed at relief of tumor‐related symptoms and catecholamine excess should be undertaken. This article is protected by copyright. All rights reserved. (Source: Head and Neck)
Source: Head and Neck - April 20, 2015 Category: ENT & OMF Authors: Vladimir Neychev, David Straughan, Karel Pacak, Electron Kebebew Tags: Case Report Source Type: research
Molecular subtypification of human papillomavirus in male adult individuals with recurrent respiratory papillomatosis
This study aimed to identify the isotype of human papillomavirus (HPV) in fresh tissue samples of 35 male adults with adult recurrent adult respiratory papillomatosis which may be important to define the precise etiology of the disease, and determine the therapeutic and prophylactic measures. (Source: Auris, Nasus, Larynx)
Source: Auris, Nasus, Larynx - April 20, 2015 Category: ENT & OMF Authors: Carmen S. García-Romero, Matsuharu Akaki-Caballero, Ana G. Saavedra-Mendoza, Ana K. Guzmán-Romero, Patricia Canto, Ramón M. Coral-Vázquez Source Type: research
Esophageal hypermotility: cause or effect?
SummaryNutcracker esophagus (NE), Jackhammer esophagus (JHE), distal esophageal spasm (DES), and hypertensive lower esophageal sphincter (HTLES) are defined by esophageal manometric findings. Some patients with these esophageal motility disorders also have abnormal gastroesophageal reflux. It is unclear to what extent these patients' symptoms are caused by the motility disorder, the acid reflux, or both. The aim of this study was to determine the effectiveness of laparoscopic Nissen fundoplication (LNF) on esophageal motility disorders, gastroesophageal reflux, and patient symptoms. Between 2007 and 2013, we performed high...
Source: Diseases of the Esophagus - April 20, 2015 Category: Gastroenterology Authors: O. M. Crespin, R. P. Tatum, R. B. Yates, M. Sahin, K. Coskun, A. V. Martin, A. Wright, B. K. Oelschlager, C. A. Pellegrini Tags: Original Article Source Type: research
Circulatory and Respiratory Parameters during Acute Endovascular Stroke Therapy in Conscious Sedation or General Anesthesia
Whether patients suffering from acute ischemic stroke and undergoing endovascular recanalization should be treated under general anesthesia (GA) or conscious sedation (CS) is a matter of debate. According to retrospective studies, GA appears to be associated with a worse outcome than CS. The underlying mechanisms are unknown, but hypotension and hypocapnia during GA have been suggested. There are no prospective data on this question. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 20, 2015 Category: Neurology Authors: Sibu Mundiyanapurath, Silvia Schönenberger, Maritoni L. Rosales, Ana M. Carrilho Romeiro, Markus Möhlenbruch, Martin Bendszus, Werner Hacke, Julian Bösel Source Type: research
Respiratory disease in pregnancy
This article deals with several important respiratory issues in pregnancy. The management of asthma, one of the most common chronic illnesses in pregnancy, remains largely unchanged compared to the non-pregnant state. Infectious respiratory illness, including pneumonia and tuberculosis are similarly managed in pregnancy with antibiotics, although special attention may be needed to antibiotic choices with more pregnancy safety data. (Source: Best Practice and Research. Clinical Obstetrics and Gynaecology)
Source: Best Practice and Research. Clinical Obstetrics and Gynaecology - April 20, 2015 Category: OBGYN Authors: Niharika Mehta, Kenneth Chen, Erica Hardy, Raumond Powrie Source Type: research
Potentiators for cystic fibrosis–targeting the underlying molecular defect
(Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - April 20, 2015 Category: Respiratory Medicine Authors: Sanjay Patel, Kevin W Southern Source Type: research
Presence of tracheal bronchus in children undergoing flexible bronchoscopy
Tracheal bronchus (TB) is a rare congenital malformation of the lung tree with a bronchus originating from the trachea. Only a small number of publications have analyzed the frequency and diagnostic procedure of TB in children, based on a restricted sample of patients. In the present study, we analyze and discuss new aspects of prevalence, clinical presentation and associated malformations of TB based on a large pediatric cohort. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - April 20, 2015 Category: Respiratory Medicine Authors: Isabelle Ruchonnet-Metrailler, Rola Abou Taam, Jacques de Blic Source Type: research
Construction of Recombinant HVT Expressing PmpD, and Immunological Evaluation against Chlamydia psittaci and Marek’s Disease Virus
In conclusion, our study suggests that the rHVT-pmpD-N live vaccine may be viable as a candidate dual vaccine that provides protection against both very virulent MDV and C. psittaci. (Source: PLoS One)
Source: PLoS One - April 20, 2015 Category: Biomedical Science Authors: Shanshan Liu et al. Source Type: research
Non-inferiority of Nitric Oxide Releasing Intranasal Spray Compared to Sub-therapeutic Antibiotics to Reduce Incidence of Undifferentiated Fever and Bovine Respiratory Disease Complex in Low to Moderate Risk Beef Cattle Arriving at a Commercial Feedlot
This study evaluated the metaphylactic use of intranasal NO releasing spray (NORS) to control BRDc incidence in calves at low-moderate risk of developing BRDc, arriving at a commercial feedlot as compared to conventional antibiotic metaphylaxis. One thousand and eighty crossbred, multiple-sourced, commingled, commercial, weaned beef calves were screened, enrolled, randomized and treated upon arrival. Animals appearing sick were pulled (from their pen) by blinded pen keepers then assessed for BRDc symptoms; blood samples were taken for haptoglobin quantification and the animals were rescued with an antibiotic. After 35 days...
Source: Preventive Veterinary Medicine - April 20, 2015 Category: Veterinary Research Source Type: research
Transmission and Effect of Multiple Clusters of Seasonal Influenza in a Swiss Geriatric Hospital
ConclusionNosocomial influenza transmission caused more secondary cases than repeated community importation during this polyclonal outbreak. Molecular tools revealed complex transmission dynamics. Low healthcare worker vaccination rates and gaps in recommended infection control procedures are likely to have contributed to nosocomial spread of influenza, which remains a potentially life‐threatening disease in elderly adults. (Source: Journal of the American Geriatrics Society)
Source: Journal of the American Geriatrics Society - April 20, 2015 Category: Geriatrics Authors: Leonardo Pagani, Yves Thomas, Benedikt Huttner, Valérie Sauvan, Grigorios Notaridis, Laurent Kaiser, Anne Iten, Didier Pittet, Stephan Harbarth Tags: Brief Report Source Type: research
Scanning the brain for answers about effectiveness of graphic warning labels
We know that smokers who perceive greater risks to their health from smoking are more likely to quit.1 Thus, while ‘traditional’ cigarette pack imagery helps to reinforce cigarette advertising and promote purchasing behaviour,2 3 graphic warning labels (GWLs) may serve as a form of ‘reverse’ advertising—increasing smokers’ knowledge about the risks associated with smoking and promoting behavioural change by preventing smoking initiation and fostering cessation.4–6 In fact, as a smoking cessation and prevention intervention, GWLs are particularly valuable since they are located dire...
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Rubinstein, M. L. Tags: Editorial Source Type: research
Worldwide news and comment
February 2015 marked 10 years since the World Health Organization Framework Convention on Tobacco Control (FCTC) entered into force. While enormous progress has been made in curtailing the epidemic, the epicentre continues to be in countries that can least afford the devastating health, social and economic costs. Despite the legal framework provided by the FCTC to stymie the activities of the industry and protect public policy from its interests, the industry continues its attempts to obstruct effective measures, either through cultivating direct relationships with government officials or resorting to legal mechanisms to i...
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Tags: TC News analysis Source Type: research
Clinical interventions to reduce secondhand smoke exposure among pregnant women: a systematic review
Conclusions Clinical interventions delivered in prenatal care settings appear to reduce SHS exposure, but study weaknesses limit our ability to draw firm conclusions. More rigorous studies, using biochemical validation, are needed to identify strategies for reducing SHS exposure in pregnant women. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Tong, V. T., Dietz, P. M., Rolle, I. V., Kennedy, S. M., Thomas, W., England, L. J. Tags: Review Source Type: research
Emotional reaction facilitates the brain and behavioural impact of graphic cigarette warning labels in smokers
Conclusions Recognition memory and craving are, respectively, correlates of effectiveness of addiction-related public health communications and interventions, and amygdala activation facilitates the encoding of emotional memories. Thus, our results suggest that emotional reaction to graphic warning labels contributes to their public health impact and may be an integral part of the neural mechanisms underlying their effectiveness. Given the urgency of the debate about the constitutional risks and public health benefits of graphic warning labels, these preliminary findings warrant consideration while longitudinal clinical st...
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Wang, A.-L., Lowen, S. B., Romer, D., Giorno, M., Langleben, D. D. Tags: Research paper Source Type: research
Do smokers support smoke-free laws to help themselves quit smoking? Findings from a longitudinal study
Conclusions Support for smoke-free laws among smokers correlates with past quit attempts and predicts future quitting. These findings are consistent with the hypothesis that some smokers support smoke-free laws because the laws could help them quit smoking. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Nagelhout, G. E., Zhuang, Y.-L., Gamst, A., Zhu, S.-H. Tags: Editor's choice Research paper Source Type: research
Human rights and ethical considerations for a tobacco-free generation
In recent years, a new tobacco ‘endgame’ has been proposed: the denial of tobacco sale to any citizen born after a certain year, thus creating new tobacco-free generations. The proposal would not directly affect current smokers, but would impose a restriction on potential future generations of smokers. This paper examines some key legal and ethical issues raised by this proposal, critically assessing how an obligation to protect human rights might limit or support a state's ability to phase out tobacco. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: van der Eijk, Y., Porter, G. Tags: Open access Research paper Source Type: research
Portrayal of tobacco use in prime-time TV dramas: trends and associations with adult cigarette consumption--USA, 1955-2010
Conclusions The correlation between tobacco portrayal in TV dramas and adult cigarette consumption is consistent with well-established effects of exposure to tobacco cues that create craving for cigarettes in adult smokers. Although tobacco use in TV dramas along with movies has declined over time, portrayal of smoking on screen media should be a focus for future adult tobacco control research and policy. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Jamieson, P. E., Romer, D. Tags: Press releases Research paper Source Type: research
Monitoring of non-cigarette tobacco use using Google Trends
Conclusions The results of this study validate that Google Trends has the potential to be a valuable monitoring tool for tobacco use. The near real-time monitoring features of Google Trends may complement traditional surveillance methods and lead to faster and more convenient monitoring of emerging trends in tobacco use. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Cavazos-Rehg, P. A., Krauss, M. J., Spitznagel, E. L., Lowery, A., Grucza, R. A., Chaloupka, F. J., Bierut, L. J. Tags: Research paper Source Type: research
Smokeless tobacco products sold in Massachusetts from 2003 to 2012: trends and variations in brand availability, nicotine contents and design features
Conclusions The number of smokeless tobacco products increased in the Massachusetts market. Further, mean unionised (free) nicotine levels in smokeless tobacco products of several manufacturers continued to rise despite decreasing levels from other manufacturers. The current success in tobacco control is very likely undermined without government surveillance, regulation and widespread public disclosure of nicotine levels in these products. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Cullen, D., Keithly, L., Kane, K., Land, T., Paskowsky, M., Chen, L., Hayes, R., Li, W. Tags: Research paper Source Type: research
Smoking-attributable burden of lung cancer in the Philippines
Conclusions Considerable health gains could be achieved if smoking exposure were reduced in the Philippines. Strong enforcement of measures like increasing taxation to the WHO-endorsed rate, expanding smoke-free environments, and requiring large graphic warnings within a comprehensive tobacco control programme is recommended. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Bilano, V. L. F., Borja, M. P., Cruz, E. L., Tan, A. G., Mortera, L. L., Reganit, P. F. M. Tags: Research paper Source Type: research
A comparison of alternative methods for measuring cigarette prices
Conclusions The TUS-CPS can be used to construct valid measures of cigarette prices. Unlike the TBOT, the TUS-CPS captures the effect of price-reducing marketing strategies, as well as tax avoidance practices and non-traditional types of purchasing. Thus, self-reported data like TUS-CPS appear to have advantages over TBOT in estimating the ‘real’ price that smokers face. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Chaloupka, F. J., Tauras, J. A., Strasser, J. H., Willis, G., Gibson, J. T., Hartman, A. M. Tags: Research paper Source Type: research
Evaluation of a community-based smoking cessation programme for people with severe mental illness
Conclusions People with mental illness are concerned about their tobacco use and will seek help if this is available. Smoking cessation programmes which are tailored for this group of smokers can be effective and should be provided by mental health and tobacco control services. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Ashton, M., Rigby, A., Galletly, C. Tags: Research paper Source Type: research
Receptivity to cigarette and tobacco control messages and adolescent smoking initiation
Conclusions Receptivity to tobacco control advertising appeared to ameliorate the promotion of initiation from cigarette advertising. Anti-industry advertising appears to be the most effective counter for tobacco control and should be considered for wider use. A larger longitudinal study is needed to confirm these findings. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Emory, K. T., Messer, K., Vera, L., Ojeda, N., Elder, J. P., Usita, P., Pierce, J. P. Tags: Research paper Source Type: research
Do consumers of manufactured cigarettes respond differently to price changes compared with their Roll-Your-Own counterparts? Evidence from New Zealand
Conclusions There is significantly different price responsiveness across the two tobacco product types. MC smokers react far more strongly to price increases compared with RYO tobacco smokers. These findings suggest that pricing mechanisms may be more effective for reducing MC demand than for RYO tobacco. However, substitution between products means that this pricing effect is muted by the uptake of RYO tobacco use. Cessation policy specific to RYO use should be designed to target this growing group. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Tait, P., Rutherford, P., Saunders, C. Tags: Research paper Source Type: research
'Herbal' but potentially hazardous: an analysis of the constituents and smoke emissions of tobacco-free waterpipe products and the air quality in the cafes where they are served
Conclusions ‘Herbal’ shisha products tested contained toxic trace metals and PAHs levels equivalent to, or in excess of, that found in cigarettes. Their mainstream and sidestream smoke emissions contained carcinogens equivalent to, or in excess of, those of tobacco products. The content of the air in the waterpipe cafés tested was potentially hazardous. These data, in aggregate, suggest that smoking ‘herbal’ shisha may well be dangerous to health. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Hammal, F., Chappell, A., Wild, T. C., Kindzierski, W., Shihadeh, A., Vanderhoek, A., Huynh, C. K., Plateel, G., Finegan, B. A. Tags: Research paper Source Type: research
What are the sales practices of internet cigar vendors in China?
Conclusions Internet cigar vendors undermine tobacco control policies and pose many challenges for tobacco control advocates in China. New legislation and enforcement should address these issues. (Source: Tobacco Control)
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Gao, J., Berg, C. J., Huang, L., Zheng, P., Fu, H. Tags: Research paper Source Type: research
Packaging digital culture to young smokers
Tobacco companies frequently seek to associate their products with certain lifestyle images in an attempt to foster brand-specific identities for their cigarettes. As demonstrated by industry-sourced segmentation analyses, for example, companies divide smokers into broad groups based on personal characteristics and strategise on how to adapt their products to increase attractiveness for these imagined communities.1–3 Linking tobacco products with the hallmarks of the digital age, such as social media and innovative technologies, seems to have become a marketing goal for a number of tobacco companies.4–6 Indeed,...
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Savelli, M., O'Connor, S. C., Di Sante, E., Cohen, J. E. Tags: Open access Industry watch Source Type: research
I 'like' MPOWER: using Facebook, online ads and new media to mobilise tobacco control communities in low-income and middle-income countries
New media campaigns hold great potential to grow public awareness about the dangers of tobacco use and advance tobacco control policies, including in low-income and middle-income countries (LMICs), which have shared in a decade of explosive growth in mobile and internet penetration. With the majority of deaths from the tobacco epidemic occurring in LMICs, new media must be harnessed both as an advocacy tool to promote social mobilisation around tobacco issues and to build public support for MPOWER policies. This paper examines three consecutive new media advocacy campaigns that used communication channels such as mobile SM...
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Hamill, S., Turk, T., Murukutla, N., Ghamrawy, M., Mullin, S. Tags: Special communication Source Type: research
Smoke spots: promoting smoking with social media
Article 13 of the Framework Convention on Tobacco Control (FCTC) requires signatories to ‘undertake a comprehensive ban of all tobacco advertising, promotion and sponsorship’.1 The FCTC defines advertising and promotion very broadly, asany form of commercial communication, recommendation or action with the aim, effect or likely effect of promoting a tobacco product or tobacco use either directly or indirectly.1 The Implementation Guidelines for the FCTC specify that:...a comprehensive ban...applies to all forms of commercial communication, recommendation or action and all forms of contribution to any event, act...
Source: Tobacco Control - April 20, 2015 Category: Respiratory Medicine Authors: Burton, S., Soboleva, A., Khan, A. Tags: Ad watch Source Type: research
Dynamic hyperinflation during activities of daily living in COPD patients.
The objective of this study was to investigate whether some activities of daily living (ADLs) usually related to dyspnea sensation in patients with chronic obstructive pulmonary disease (COPD) are associated with dynamic lung hyperinflation (DH) and whether the use of simple energy conservation techniques (ECTs) might reduce this possible hyperinflation. Eighteen patients (mean age: 65.8 ± 9.8 years) with moderate-to-severe COPD performed six ADLs (walking on a treadmill, storing pots, walking 56 meters carrying a 5-kilogram weight, climbing stairs, simulating taking a shower, and putting on shoes) and had their inspirato...
Source: Chronic Respiratory Disease - April 20, 2015 Category: Respiratory Medicine Authors: Silva CS, Nogueira FR, Porto EF, Gazzotti MR, Nascimento OA, Camelier A, Jardim JR Tags: Chron Respir Dis Source Type: research
Leucothrix pacifica sp. nov., isolated from seawater of South Pacific Gyre and emended description of the genus Leucothrix.
Abstract A Gram-stain-negative, strictly aerobic, non-flagellated, non-gliding, oxidase- and catalase-positive, white-pigmented and rod-shaped bacterium, designated strain XH122T, was isolated from surface seawater sample collected from the South Pacific Gyre (45°58' E, 163°11' S) during the Integrated Ocean Drilling Program (IODP) Expedition 329. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain XH122T belonged to the genus Leucothrix and showed the highest 16S rRNA gene sequence similarity with Leucothrix mucor DSM 2157T (94.3%). It showed lower sequence similarities (< 90.7 %) wit...
Source: International Journal of Systematic and Evolutionary Microbiology - April 20, 2015 Category: Microbiology Authors: Zhang Z, Gao X, Wang L, Zhang XH Tags: Int J Syst Evol Microbiol Source Type: research
Limnochorda pilosa gen. nov., sp. nov., a moderately thermophilic, facultative anaerobic pleomorphic bacterium and proposal of Limnochordaceae fam. nov., Limnochordales ord. nov. and Limnochordia classis nov. in the phylum Firmicutes.
Abstract A novel facultative anaerobic bacterium, strain HC45T was isolated from sediment of a brackish meromictic lake in Japan, Lake Harutori. Cells were pleomorphic, and filamentous bodies were 5-100 µm in length. For growth, the optimum pH was 7.0 and the optimum temperature was 45-50ºC. The G+C content of the genomic DNA was 71 mol%. Iso-C15:0 and anteiso-C15:0 were the major components in the cellular fatty acid profile. Predominant respiratory quinone was MK-7. The strain HC45T had exceedingly low similarity of the 16S rRNA gene with cultivated strains (85% or less). Phylogenetic analysis based on the 16S ...
Source: International Journal of Systematic and Evolutionary Microbiology - April 20, 2015 Category: Microbiology Authors: Watanabe M, Kojima H, Fukui M Tags: Int J Syst Evol Microbiol Source Type: research
From the acta prize lecture 2014: the periodontal-systemic connection seen from a microbiological standpoint.
CONCLUSION: Periodontal bacteria may participate in extra-oral infections such as CVD, diabetes, APO, pre-eclampsia, COPD, pneumonia, RA, CKD, obesity, cancer, MetS and cognitive impairment. Most knowledge is based on associations which do not necessarily imply causality. Future studies should reach consensus on the definition of PD and systemic disease outcomes, recognize the full spectrum of the microbiota in PD and bacteremia, including not-yet-cultivated organisms and delineate the clinical significance of genetic strain variations and the role of periodontopathogenic vs gut organisms within atheromatous lesions. For d...
Source: Acta Odontologica Scandinavica - April 20, 2015 Category: Dentistry Authors: Olsen I Tags: Acta Odontol Scand Source Type: research
Saline nasal irrigation for acute upper respiratory tract infections.
CONCLUSIONS: Nasal saline irrigation possibly has benefits for relieving the symptoms of acute URTIs. However, the included trials were generally too small and had a high risk of bias, reducing confidence in the evidence supporting this. Future trials should involve larger numbers of participants and report standardised and clinically meaningful outcome measures. PMID: 25892369 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 20, 2015 Category: Journals (General) Authors: King D, Mitchell B, Williams CP, Spurling GK Tags: Cochrane Database Syst Rev Source Type: research
Air Pollution and Respiratory Health in Childhood.
PMID: 25907236 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - April 20, 2015 Category: Respiratory Medicine Authors: Gascon M, Sunyer J Tags: Arch Bronconeumol Source Type: research
Elevated Extravascular Lung Water Index (ELWI) as a Predictor of Failure of Continuous Positive Airway Pressure Via Helmet (Helmet-CPAP) in Patients With Acute Respiratory Failure After Major Surgery.
CONCLUSION: In this type of patient the physiological parameters that predict the failure of Helmet-CPAP with the greatest accuracy were the value of the EVLWI and PVPI before Helmet-CPAP institution and the PaO2/FiO2 ratio and the respiratory rate after one hour of CPAP. PMID: 25907235 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - April 20, 2015 Category: Respiratory Medicine Authors: Redondo Calvo FJ, Bejarano Ramirez N, Uña Orejon R, Villazala Garcia R, Yuste Peña AS, Belda FJ Tags: Arch Bronconeumol Source Type: research
Miliary Tuberculosis With Vertebral Involvement (Pott's Disease).
PMID: 25907234 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - April 20, 2015 Category: Respiratory Medicine Authors: Ariza-Prota M, Pando-Sandoval A, García-Clemente M Tags: Arch Bronconeumol Source Type: research
The Contribution of Cell Blocks in the Diagnosis of Mediastinal Masses and Hilar Adenopathy Samples from Echobronchoscopy.
PMID: 25907233 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - April 20, 2015 Category: Respiratory Medicine Authors: Franco Serrano J, Burés Sales E Tags: Arch Bronconeumol Source Type: research
Mortality Attributable to Seasonal Influenza A and B Infections in Thailand, 2005-2009: A Longitudinal Study.
Abstract Influenza epidemiology differs substantially in tropical and temperate zones, but estimates of seasonal influenza mortality in developing countries in the tropics are lacking. We aimed to quantify mortality due to seasonal influenza in Thailand, a tropical middle-income country. Time series of polymerase chain reaction-confirmed influenza infections between 2005 and 2009 were constructed from a sentinel surveillance network. These were combined with influenza-like illness data to derive measures of influenza activity and relationships to mortality by using a Bayesian regression framework. We estimated 6.1 ...
Source: Am J Epidemiol - April 20, 2015 Category: Epidemiology Authors: Cooper BS, Kotirum S, Kulpeng W, Praditsitthikorn N, Chittaganpitch M, Limmathurotsakul D, Day NP, Coker R, Teerawattananon Y, Meeyai A Tags: Am J Epidemiol Source Type: research
Methylisothiazolinone: Dermal and respiratory immune responses in mice.
In this study, we investigated the capacity of MI to elicit asthma-like responses in a validated mouse model. On days 1 and 8, mice (C57Bl/6 and BALB/c) were dermally treated with MI or vehicle on each ear. On day 15, mice received a single intranasal challenge with MI or vehicle. Immediately after the challenge, the early ventilatory response was measured using a double chamber plethysmograph. One day later, airway hyperreactivity, pulmonary inflammation and immune-related parameters were assessed. Dermal treatment with MI in both C57Bl/6 and BALB/c mice induced increased T- and B-cell proliferation in the auricular lymph...
Source: Toxicology Letters - April 20, 2015 Category: Toxicology Authors: Devos FC, Pollaris L, Van Den Broucke S, Seys S, Goossens A, Nemery B, Hoet PH, Vanoirbeek JA Tags: Toxicol Lett Source Type: research
The amino acid residues at 102 and 104 in GP5 of porcine reproductive and respiratory syndrome virus regulate viral neutralization susceptibility to the porcine serum neutralizing antibody.
In this study, the important amino acid (aa) residues of HP-PRRSV strain BB affecting neutralization susceptibility of antibody were examined using resistant strains generated under neutralizing antibody (NAb) pressure in MARC-145 cells, reverse genetic technique and virus neutralization assay. HP-PRRSV strain BB was passaged under the pressure of porcine NAb serum in vitro. A resistant strain BB34s with 102 and 104 aa substitutions in GP5, which have been predicted to be the positive sites for pressure selection (Delisle et al., 2012), was cloned and identified. To determine the effect of the two aa residues on neutraliza...
Source: Virus Research - April 20, 2015 Category: Virology Authors: Fan B, Liu X, Bai J, Zhang T, Zhang Q, Jiang P Tags: Virus Res Source Type: research
Inhaled antimicrobial chemotherapy for respiratory tract infections: successes, challenges and the road ahead.
PMID: 25907147 [PubMed - as supplied by publisher] (Source: Advanced Drug Delivery Reviews)
Source: Advanced Drug Delivery Reviews - April 20, 2015 Category: Drugs & Pharmacology Authors: Chan HK, Li J Tags: Adv Drug Deliv Rev Source Type: research
[Comment] Efficacy of idebenone in Duchenne muscular dystrophy
In The Lancet, Gunnar Buyse and colleagues1 report the results of DELOS, a double-masked, randomised, placebo-controlled, multicentre, phase 3 trial investigating the efficacy of idebenone on respiratory outcomes in patients with Duchenne muscular dystrophy. The authors report for the first time the possible efficacy of a non-steroidal drug in a cohort of patients with Duchenne muscular dystrophy, most of whom were non-ambulant. The results are promising because of the favourable safety profile of idebenone, but also show that challenges exist for studies in people with this disease, especially non-ambulant patients, and r...
Source: LANCET - April 20, 2015 Category: Journals (General) Authors: Eugenio Mercuri, Francesco Muntoni Tags: Comment Source Type: research