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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 16.

Across the pulmonary epithelial barrier: Integration of physicochemical properties and human cell models to study pulmonary drug formulations
Publication date: December 2014 Source:Pharmacology & Therapeutics, Volume 144, Issue 3 Author(s): Mehra Haghi , Hui Xin Ong , Daniela Traini , Paul Young During the process of inhalable formulation development a deep knowledge of the physicochemical characteristics of the drug and formulation components and the biological properties of the airways is necessary. For example, the solubility and lipophilicity of a drug may affect therapeutic efficacy by changing the residence time of the microparticles at the airway surface. Furthermore, the properties of microparticles, such as shape, size and density, as well as ...
Source: Pharmacology and Therapeutics - November 18, 2014 Category: Drugs & Pharmacology Source Type: research

Diffuse pulmonary ossification in permanent vegetative state
We present here the first case of DPO associated with a long‐lasting vegetative state. Micro‐computed tomography (MicroCT) was applied to analyze the distribution of pulmonary ossification in volumes of lung samples. It showed a mean volume percentage of ossification of 0.79% and 3‐D reconstructions permitted to reveal the branching pattern and internal cavities of some ossifications. The occurrence of DPO in a persistent vegetative state (PVS) may be favored by recurrent pulmonary infections, due to aspiration and immunological defects, and respiratory instability, due to brain damage and the fact of being bedridden...
Source: Pathology International - November 18, 2014 Category: Pathology Authors: Andrea Porzionato, Veronica Macchi, Ugo Da Broi, Chiara Giraudo, Diego Miotto, Daniele Rodriguez, Carlo Moreschi, Raffaele De Caro Tags: Case Report Source Type: research

Neonatal Airway Infection Due to Herpes Simplex Virus
A 6-day-old boy was transferred to our hospital due to high fever and respiratory distress. He weighed 3.2 kg at birth, and he was breast fed from birth. His mother had an uncomplicated pregnancy and a normal vaginal delivery. He presented with cyanosis, productive cough, hoarseness, and subcostal retractions; oxygen supplementation was immediately given. The leukocyte count was 4050/μL. C-reactive protein was 66 mg/L. Laryngeal fiberscope examinations, which was carried out under controlled situation, revealed edematous epiglottis covered with white exudate plaques (Figure 1). (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - November 18, 2014 Category: Pediatrics Authors: Michiko F. Abe, Shuji Sai, Kiyotaka Kosugiyama Tags: Insights and Images Source Type: research

Improved metabolic regulation is associated with retinoblastoma protein gene haploinsufficiency in mice.
In conclusion, Rb haploinsufficiency provides metabolic advantages in front of acute metabolic stressors and ameliorates body fat gain and metabolic and physiological impairments that normally accompany transition from young to mature adult age. PMID: 25406261 [PubMed - as supplied by publisher] (Source: Am J Physiol Endocri...)
Source: Am J Physiol Endocri... - November 18, 2014 Category: Endocrinology Authors: Petrov PD, Ribot J, Palou A, Bonet ML Tags: Am J Physiol Endocrinol Metab Source Type: research

In this issue of Occupational Medicine
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Nimmo, S. Tags: In This Issue Source Type: research

Personality disorders in the workplace
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Tyrer, P. Tags: Editorial Source Type: research

Occupational Medicine Calendar
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Tags: Calendar Source Type: research

X-rays as art
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: McKiernan, M. Tags: Art and occupation Source Type: research

Age, occupational demands and the risk of serious work injury
Conclusions This study’s results suggest that although older workers and occupations with higher demands should be the targets of primary preventive efforts related to serious musculoskeletal injuries, there may also be gains in targeting middle-aged workers in the most physically demanding occupations. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Smith, P. M., Berecki-Gisolf, J. Tags: The older worker Original Paper Source Type: research

Employers' views on the fit note
Conclusions The fit note has the potential to promote an earlier return to work. In order for the fit note to achieve its aim, further understanding of the difficulties employers are having when making return to work decisions is important, in order to develop guidance to enable them to provide the practical support employees need to return to work sooner. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Kotze, E. Tags: Original Paper Source Type: research

Covariates of alcohol consumption among career firefighters
Conclusions Drinking levels observed in this study exceed those of the general adult population, including college students. Thus, it appears that firefighters represent an at-risk drinking group. Further investigations addressing reasons for alcohol use and abuse among firefighters are warranted. This study and subsequent research will provide information necessary for the development and testing of tailored interventions aimed at reducing firefighter alcohol consumption. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Piazza-Gardner, A. K., Barry, A. E., Chaney, E., Dodd, V., Weiler, R., Delisle, A. Tags: Original Paper Source Type: research

Physical and psychological determinants of injury in Ontario forest firefighters
Conclusions First aid and WSIB injuries in the OMNR AFFES were quite distinct phenomena and different factors need consideration in their prediction. It is recommended that managers and decision-makers in this field consider factors such as job stress, personality and the prior occurrence of injuries in their assessment of risk. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Gordon, H., Lariviere, M. Tags: Fire and rescue service, Occupational stress Original Paper Source Type: research

Shale is here again
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Seaton, A. Tags: Filler Source Type: research

Cardiorespiratory fitness in a representative sample of Belgian firefighters
Conclusions The study provided representative data on cardiorespiratory fitness, BMI and total body fat percentage for Belgian firefighters. The findings suggest the need for a structural approach on healthy eating and regular physical exercise in firefighters. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Kiss, P., De Meester, M., Maes, C., De Vriese, S., Kruse, A., Braeckman, L. Tags: Fire and rescue service Original Paper Source Type: research

Cross-national comparison of job satisfaction in doctors during economic recession
Conclusions Job satisfaction in doctors was lower in Iceland than in Norway, which may have been attributable partly to the current economic recession. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Solberg, I. B., Tomasson, K., Aasland, O., Tyssen, R. Tags: Occupational stress Original Paper Source Type: research

Musculoskeletal disorders among nurses compared with two other occupational groups
Conclusions LBP continues to have a substantial impact among nurses. Other less commonly considered MSDs, such as shoulder, wrist/hand and knee pain, also made work or functional tasks difficult, suggesting that primary and secondary prevention efforts should consider MSDs at other anatomical sites as well as the low back. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Harcombe, H., Herbison, G. P., McBride, D., Derrett, S. Tags: Original Paper Source Type: research

Cost and disability trends of work-related musculoskeletal disorders in Ohio
Conclusions Ageing appeared to have a role in the frequency and costs of musculoskeletal disorder claims in this study. However, industry-specific trends in the data suggest that job-specific risk factors may also play a role. The impact of age alone on the cost of musculoskeletal disorders cannot be determined because age is confounded by numerous lifestyle and work-related factors not identifiable in this study. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Davis, K., Dunning, K., Jewell, G., Lockey, J. Tags: Original Paper Source Type: research

Rest and recuperation in the UK Armed Forces
Conclusions These preliminary data suggest that R&R can be useful for troops if they can use the time to recover. This study’s results are relevant to policymakers and leaders in the military and other groups placed in challenging environments but more work is needed to understand how R&R works and to maximize its capacity to promote well-being among military personnel. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Parsloe, L., Jones, N., Fertout, M., Luzon, O., Greenberg, N. Tags: Occupational stress, Post-traumatic stress Original Paper Source Type: research

Heavy overtime work and depressive disorder among male workers
Conclusions Heavy overtime work is a risk factor for the new onset of depressive disorder in this population of male workers. Working >60h per week may be the cut-off to screen for high-risk groups who need preventive action against depressive disorder. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Kato, R., Haruyama, Y., Endo, M., Tsutsumi, A., Muto, T. Tags: Mental health Original Paper Source Type: research

Hammerfest: occupational medicine at 70{degrees} north
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Hirons, E. Tags: Oil and gas industry, Remote medicine Filler Source Type: research

Work ability in vibration-exposed workers
Conclusions Vibration-exposed workers showed raised vibrotactile and thermal perception thresholds, compared with unexposed referents. Multiple regression analysis indicated that stress disorders and muscle pain in hands/arms must also be considered when evaluating work ability among subjects with HAVS. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Gerhardsson, L., Hagberg, M. Tags: Vibration Original Paper Source Type: research

Hunting canaries
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Gibson, M. Tags: Military - Fitness for Work Filler Source Type: research

Breast cancer and work outcomes in health care workers
Conclusions This study showed a higher return to work rate in the first year, following treatment for breast cancer, than described previously. Workplace adjustments, recommended by an occupational physician, were provided for the majority. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Goss, C., Leverment, I. M. G., de Bono, A. M. Tags: Chronic disease Original Paper Source Type: research

Direct and indirect effects of organizational justice on work ability
Conclusions This study showed the importance of considering additional indirect pathways when examining the impact of OJ on the work ability of employees. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Spanier, K., Radoschewski, F. M., Gutenbrunner, C., Bethge, M. Tags: Occupational stress Original Paper Source Type: research

Respiratory function in power plant workers exposed to nitrogen dioxide
Conclusions Occupational exposure to NO2 emissions in power plants is significantly associated with lung function abnormalities as assessed by spirometry. Spirometric measurements in power plant workers exposed to NO2 emissions may be an effective means of detecting early signs of impaired respiratory health in this group of workers. (Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Carbone, U., Montuori, P., Novi, C., Triassi, M. Tags: Respiratory Disorders Original Paper Source Type: research

Consent for release of confidential information--ethics in context?
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Tamin, J. Tags: Letter to the Editor Source Type: research

Under-recording of sickness absence in doctors
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Lalloo, D., Ghafur, I., Macdonald, E. B. Tags: Healthcare workers Letter to the Editor Source Type: research

Fifty years ago: 'Parameters of occupational health in America'
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Tags: Filler Source Type: research

Dermatotoxicology
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Trakoli, A. Tags: Book Review Source Type: research

Global Mental Health: Principles and Practice
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Snashall, D. Tags: Book Review Source Type: research

Thank you to reviewers 64-8
(Source: Occupational Medicine)
Source: Occupational Medicine - November 18, 2014 Category: Respiratory Medicine Tags: List of reviewers Source Type: research

Exercise training for asbestos-related and other dust-related respiratory diseases: a randomised controlled trial
Conclusion: Exercise training improved short and long-term exercise capacity and HRQoL in people with dust-related pleural and interstitial respiratory diseases.Clinical trial registration number: ANZCTR12608000147381. Date trial registered: 27.03.2008. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - November 18, 2014 Category: Respiratory Medicine Authors: Marita DaleZoe McKeoughPhillip MunozPeter CortePeter ByeJennifer Alison Source Type: research

Corrigendum to “Efficacy and safety of fluticasone furoate 100 μg once-daily in patients with persistent asthma: A 24-week placebo and active-controlled randomised trial” [Res Med 108 (2014) 41–49]
The authors regret that an error occurred in Table 2 in the above-mentioned article. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - November 18, 2014 Category: Respiratory Medicine Authors: Jan Lötvall, Eugene R. Bleecker, William W. Busse, Paul M. O'Byrne, Ashley Woodcock, Edward M. Kerwin, Sally Stone, Richard Forth, Loretta Jacques, Eric D. Bateman Tags: Corrigendum Source Type: research

Minimization of extracellular space as a driving force in prokaryote association and the origin of eukaryotes
Conclusions: This benefit may be a driving force in biofilm formation. Under this hypothesis a very wide range of prokaryotic species combinations could serve as eukaryotic progenitors. We use this observation and the discovery of prokaryotic nanotubes to propose that eukaryotes arose from physically distinct, functionally specialized (energy factory, protein factory, DNA repository/RNA factory), obligatorily symbiotic prokaryotes in which the protein factory and DNA repository/RNA factory cells were coupled by nanotubes and the protein factory ultimately internalized the other two. This hypothesis naturally explains many ...
Source: Biology Direct - November 18, 2014 Category: Biology Authors: Scott HooperHelaine Burstein Source Type: research

Cecropin P1 inhibits porcine reproductive and respiratory syndrome virus by blocking attachment
Conclusions: Collectively, our findings provide a new direction for the development of potential therapeutic drugs against PRRSV infection. (Source: BMC Microbiology)
Source: BMC Microbiology - November 18, 2014 Category: Microbiology Authors: Chunhe GuoYumao HuangPeiqing CongXiaohong LiuYaosheng ChenZuyong He Source Type: research

Drug sales data analysis for outbreak detection of infectious diseases: a systematic literature review
Conclusions: Drug sales data analyses appear to be a useful tool for surveillance of gastrointestinal and respiratory disease, and OTC drugs have the potential for early outbreak detection. Their utility remains to be investigated for other diseases, in particular those poorly surveyed. (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - November 18, 2014 Category: Infectious Diseases Authors: Mathilde PivetteJudith MuellerPascal CrépeyAvner Bar-Hen Source Type: research

Grape seed procyanidin B2 ameliorates mitochondrial dysfunction and inhibits apoptosis via the AMP-activated protein kinase-silent mating type information regulation 2 homologue 1-PPARγ co-activator-1α axis in rat mesangial cells under high-dose glucosamine.
Abstract Grape seed procyanidin B2 (GSPB2), an antioxidative and anti-inflammatory polyphenol in grape seed, has been found to have protective effects on diabetic nephropathy. Based on its favourable biological activities, in the present study, we aimed to investigate whether GSPB2 could inhibit apoptosis in rat mesangial cells treated with glucosamine (GlcN) under high-dose conditions. The results showed that the administration of GSPB2 (10 μg/ml) significantly increased the viability of mesangial cells treated with GlcN at a dose of 15 mm. We found that GSPB2 inhibited apoptosis in mesangial cells using termin...
Source: The British Journal of Nutrition - November 18, 2014 Category: Nutrition Authors: Bao L, Cai X, Zhang Z, Li Y Tags: Br J Nutr Source Type: research

Comparison of Cardiorespiratory Responses During Aquatic and Land Treadmill Exercise in Patients With Coronary Artery Disease.
CONCLUSIONS:: This study demonstrated that aquatic treadmill exercise elicits similar peak cardiorespiratory responses compared with land treadmill exercise, suggesting that aquatic treadmill exercise may be effective for CAD patients in cardiac rehabilitation. PMID: 25407597 [PubMed - as supplied by publisher] (Source: Journal of Cardiopulmonary Rehabilitation and Prevention)
Source: Journal of Cardiopulmonary Rehabilitation and Prevention - November 18, 2014 Category: Rehabilitation Authors: Choi JH, Kim BR, Joo SJ, Han EY, Kim SY, Kim SM, Lee SY, Yoon HM Tags: J Cardiopulm Rehabil Prev Source Type: research

Cardiocirculatory Monitoring during Immediate Fetal-to-Neonatal Transition: A Systematic Qualitative Review of the Literature.
Conclusion: Routine HR monitoring using electrocardiography or pulse oximetry is used to evaluate adequate hemodynamic transition, and reference ranges have been established. Measuring blood pressure noninvasively though noncontinuously might be of some value in future, considering that the normative data have been established recently. Echocardiographic monitoring during the immediate transition period will improve the knowledge about cardiac function changes, but introduction in clinical routine remains questionable. © 2014 S. Karger AG, Basel. PMID: 25412794 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - November 18, 2014 Category: Perinatology & Neonatology Authors: Baik N, Urlesberger B, Schwaberger B, Freidl T, Schmölzer GM, Pichler G Tags: Neonatology Source Type: research

Dissection of the genus Actinobaculum: Reclassification of Actinobaculum schaalii Lawson et al. 1997 and Actinobaculum urinale Hall et al. 2003 as Actinotignum schaalii gen. nov., comb. nov. and Actinotignum urinale comb. nov., description of Actinotignum sanguinis sp. nov. and emended description of the genus Actinobaculum. Re-examination of Actinobaculum massiliense culture deposited as CCUG 47753T (=DSM 19118T) revealed that it does not represent a strain of this species.
Abstract The remarkable host specificity of Actinobaculum species directed our attention to recharacterize these species by a polyphasic approach. A comparative chemotaxonomic study including analysis of whole-cell sugars, amino acid composition of the peptidoglycan, fatty acid methyl esters, respiratory quinones and polar lipids reveals significant differences that, in combination with molecular data, support a dissection of the genus Actinobaculum. The proposals of this study include the reclassification of Actinobaculum schaalii and Actinobaculum urinale as Actinotignum schaalii gen. nov., comb. nov. (type strai...
Source: International Journal of Systematic and Evolutionary Microbiology - November 18, 2014 Category: Microbiology Authors: Yassin AA, Sproeer C, Pukall R, Sylvester M, Siering C, Schumann P Tags: Int J Syst Evol Microbiol Source Type: research

Cardiocirculatory Monitoring during Immediate Fetal-to-Neonatal Transition: A Systematic Qualitative Review of the Literature
Conclusion: Routine HR monitoring using electrocardiography or pulse oximetry is used to evaluate adequate hemodynamic transition, and reference ranges have been established. Measuring blood pressure noninvasively though noncontinuously might be of some value in future, considering that the normative data have been established recently. Echocardiographic monitoring during the immediate transition period will improve the knowledge about cardiac function changes, but introduction in clinical routine remains questionable.Neonatology 2015;107:100-107 (Source: Neonatology)
Source: Neonatology - November 17, 2014 Category: Perinatology & Neonatology Source Type: research

Longitudinal associations between temperament and socioemotional outcomes in young children: The moderating role of RSA and gender
ABSTRACT Temperament is an important predictor of socioemotional adjustment, such as externalizing and internalizing symptoms. However, there is not a one‐to‐one correspondence between temperamental predispositions and these outcomes, implying that other factors also contribute to the development of internalizing and externalizing problems. Self‐regulation is believed to interact with temperament, and has been studied as a predictor for later socioemotional outcomes. Respiratory sinus arrhythmia (RSA) is a psychophysiological measure of self‐regulation that has been studied as a moderator of risk. The primary aim o...
Source: Developmental Psychobiology - November 17, 2014 Category: Psychiatry & Psychology Authors: Santiago Morales, Charles Beekman, Alysia Y. Blandon, Cynthia A. Stifter, Kristin A. Buss Tags: Research Article Source Type: research

Breast-Feeding and Health Consequences in Early Childhood: Is There an Impact of Time-Dependent Confounding?
Conclusions: In two cohort studies, there was little evidence of time-dependent confounding by weight, length, rash, respiratory illness or day care attendance of the effects of breast-feeding on early childhood health.Ann Nutr Metab 2014;65:139-148 (Source: Annals of Nutrition and Metabolism)
Source: Annals of Nutrition and Metabolism - November 17, 2014 Category: Nutrition Source Type: research

Maternal and paternal beliefs, support and parenting as determinants of sport participation of adolescents with asthma
Journal of Asthma, Ahead of Print. (Source: Journal of Asthma)
Source: Journal of Asthma - November 17, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Impaired Hypercarbic and Hypoxic Responses from Developmental Loss of Cerebellar Purkinje Neurons: Implications for Sudden Infant Death Syndrome
Abstract Impaired responsivity to hypercapnia or hypoxia is commonly considered a mechanism of failure in sudden infant death syndrome (SIDS). The search for deficient brain structures mediating flawed chemosensitivity typically focuses on medullary regions; however, a network that includes Purkinje cells of the cerebellar cortex and its associated cerebellar nuclei also helps mediate responses to carbon dioxide (CO2) and oxygen (O2) challenges and assists integration of cardiovascular and respiratory interactions. Although cerebellar nuclei contributions to chemoreceptor challenges in adult models are well descr...
Source: The Cerebellum - November 17, 2014 Category: Neurology Source Type: research

Performance of the Simplexa™ Flu A/B & RSV Direct Kit on respiratory samples collected in saline solution
Scandinavian Journal of Infectious Diseases, Volume 46, Issue 12, Page 825-831, December 2014. (Source: Scandinavian Journal of Infectious Diseases)
Source: Scandinavian Journal of Infectious Diseases - November 17, 2014 Category: Infectious Diseases Tags: article Source Type: research

Comparison of the FilmArray assay and in-house real-time PCR for detection of respiratory infection
Scandinavian Journal of Infectious Diseases, Volume 46, Issue 12, Page 897-901, December 2014. (Source: Scandinavian Journal of Infectious Diseases)
Source: Scandinavian Journal of Infectious Diseases - November 17, 2014 Category: Infectious Diseases Tags: article Source Type: research