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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 16.

Manual vs. pressure‐controlled facemask ventilation for anaesthetic induction in paralysed children: a randomised controlled trial
ConclusionAlthough PCV provided lower PAP than MV at the same tidal volume, the risk of GI may not be eliminated during facemask ventilation in paralysed small children. (Source: Acta Anaesthesiologica Scandinavica)
Source: Acta Anaesthesiologica Scandinavica - April 24, 2016 Category: Anesthesiology Authors: J. H. Park, J. Y. Kim, J. M. Lee, Y. H. Kim, H. W. Jeong, H. K. Kil Tags: Original Article Source Type: research

Long‐term efficacy and safety results of taliglucerase alfa up to 36 months in adult treatment‐naïve patients with Gaucher disease
Taliglucerase alfa is an intravenous enzyme replacement therapy approved for treatment of type 1 Gaucher disease (GD), and is the first available plant cell–expressed recombinant therapeutic protein. Herein, we report long‐term safety and efficacy results of taliglucerase alfa in treatment‐naïve adult patients with GD. Patients were randomized to receive taliglucerase alfa 30 or 60 U/kg every other week, and 23 patients completed 36 months of treatment. Taliglucerase alfa (30 U/kg; 60 U/kg, respectively) resulted in mean decreases in spleen volume (50.1%; 64.6%) and liver volume (25.6%; 24.4%) with mean increases in...
Source: American Journal of Hematology - April 24, 2016 Category: Hematology Authors: Ari Zimran, Gloria Durán, Atul Mehta, Pilar Giraldo, Hanna Rosenbaum, Fiorina Giona, Dominick J. Amato, Milan Petakov, Eduardo Terreros Muñoz, Sergio Eduardo Solorio‐Meza, Peter A. Cooper, Sheeba Varughese, Raul Chertkoff, Einat Brill‐Almon Tags: Research Article Source Type: research

Immune responses to modified live virus vaccines developed from classical or highly pathogenic PRRSV following challenge with a highly pathogenic PRRSV strain.
This study characterized the protective efficacy and immune response to MLVs from C-PRRSV (CH-1R) or HP-PRRSV (HuN4-F112) in a challenge using HP-PRRSV (HuN4). The outcomes were clinical signs of disease, pathological changes in the thymus and lungs, viremia, and humoral and cellular immune responses. CH-1R provided some protection against challenge with HuN4, while HuN4-F112 was protective in the HuN4 challenge. Compared to unvaccinated piglets, the vaccinated piglets had milder symptoms and fewer pathological changes in the lung and thymus. Piglets vaccinated with HuN4-F112 had higher antibody titers and lower viral load...
Source: Developmental and Comparative Immunology - April 24, 2016 Category: Allergy & Immunology Authors: Wang G, Yu Y, Zhang C, Tu Y, Tong J, Liu Y, Chang Y, Jiang C, Wang S, Zhou EM, Cai X Tags: Dev Comp Immunol Source Type: research

Inhaler technique: facts and fantasies. A view from the Aerosol Drug Management Improvement Team (ADMIT).
Abstract Health professionals tasked with advising patients with asthma and chronic obstructive pulmonary disease (COPD) how to use inhaler devices properly and what to do about unwanted effects will be aware of a variety of commonly held precepts. The evidence for many of these is, however, lacking or old and therefore in need of re-examination. Few would disagree that facilitating and encouraging regular and proper use of inhaler devices for the treatment of asthma and COPD is critical for successful outcomes. It seems logical that the abandonment of unnecessary or ill-founded practices forms an integral part of ...
Source: Respiratory Care - April 23, 2016 Category: Respiratory Medicine Authors: Levy ML, Dekhuijzen PN, Barnes PJ, Broeders M, Corrigan CJ, Chawes BL, Corbetta L, Dubus JC, Hausen T, Lavorini F, Roche N, Sanchis J, Usmani OS, Viejo J, Vincken W, Voshaar T, Crompton GK, Pedersen S Tags: NPJ Prim Care Respir Med Source Type: research

Coenzyme Q10 analytical determination in biological matrices and pharmaceuticals.
Authors: Lucangioli S, Martinefski M, Tripodi V Abstract In recent years, the analytical determination of coenzyme Q10 (CoQ10) has gained importance in clinical diagnosis and in pharmaceutical quality control. CoQ10 is an important cofactor in the mitochondrial respiratory chain and a potent endogenous antioxidant. CoQ10 deficiency is often associated with numerous diseases and patients with these conditions may benefit from administration of supplements of CoQ10. In this regard, it has been observed that the best benefits are obtained when CoQ10 deficiency is diagnosed and treated early. Therefore, it is of great ...
Source: Frontiers in Bioscience - Scholar - April 23, 2016 Category: Biomedical Science Tags: Front Biosci (Schol Ed) Source Type: research

Assessment of biological responses of EpiAirway 3-D cell constructs versus A549 cells for determining toxicity of ambient air pollution.
CONCLUSION: LDH and IL-8 are robust endpoints for assessing toxicity in A549 cells. The EpiAirway(TM) cells show minimal adverse effects after exposure suggesting that they are more toxicologically resistant compared to A549 cells. Higher concentrations or longer exposure times are needed to induce effects on EpiAirway(TM) cells. PMID: 27100558 [PubMed - in process] (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - April 23, 2016 Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research

Biological responses of Raw 264.7 macrophage exposed to two strains of Stachybotrys chartarum spores grown on four different wallboard types.
Authors: Kim JH, Harvey LA, Evans AL, Byfield GE, Betancourt DA, Dean TR Abstract The many benefits of building "green" have motivated the use of sustainable products in the design and execution of the built environment. However, the use of these natural or recycled materials, some of which have been treated with antimicrobials, provides a growth opportunity for microorganisms with the potential to elicit adverse health effects especially in the presence of an antimicrobial. The focus of this research was to determine the effects of Stachybotrys chartarum (strains Houston and 51-11) grown under different conditions...
Source: Inhalation Toxicology - April 23, 2016 Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research

Age-related differences in pulmonary effects of acute and subchronic episodic ozone exposures in Brown Norway rats.
In this study, we examined age-related susceptibility to O3 using 1 mo (adolescent), 4 mo (young adult), 12 mo (adult) and 24 mo (senescent) male Brown Norway rats exposed to filtered air or O3 (0.25 and 1.00 ppm), 6 h/day, two days/week for 1 week (acute) or 13 weeks (subchronic). Ventilatory function, assessed by whole-body plethysmography, and bronchoalveolar lavage fluid (BALF) biomarkers of injury and inflammation were used to examine O3-induced pulmonary effects. Relaxation time declined in all ages following the weekly exposures; however, this effect persisted only in the 24 mo rats following a five da...
Source: Inhalation Toxicology - April 23, 2016 Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research

Carriage, Clinical Microbiology and Transmission of Staphylococcus aureus.
Authors: Aryee A, Edgeworth JD Abstract Staphylococcus aureus is one of the most important bacterial pathogens in clinical practice and a major diagnostic focus for the routine microbiology laboratory. It is carried as a harmless commensal in up to two-thirds of the population at any one time predominantly not only in the anterior nares, but also in multiple other sites such as the groin, axilla, throat, perineum, vagina and rectum. It colonizes skin breach sites, such as ulcers and wounds, and causes superficial and deep skin and soft tissue infections and life-threatening deep seated infections particularly endoc...
Source: Current Topics in Microbiology and Immunology - April 23, 2016 Category: Microbiology Tags: Curr Top Microbiol Immunol Source Type: research

Lung functions among patients with pulmonary tuberculosis in Dar es Salaam – a cross-sectional study
Approximately 40–60 % of patients remain sufferers of sequela of obstructive, restrictive or mixed patterns of lung disease despite treatment for pulmonary tuberculosis (PTB). The prevalence of these abnormali... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 23, 2016 Category: Respiratory Medicine Authors: Mohamed Manji, Grace Shayo, Simon Mamuya, Rose Mpembeni, Ahmed Jusabani and Ferdinand Mugusi Source Type: research

Regeneration of the lung: Lung stem cells and the development of lung mimicking devices
Inspired by the increasing burden of lung associated diseases in society and an growing demand to accommodate patients, great efforts by the scientific community produce an increasing stream of data that are f... (Source: Respiratory Research)
Source: Respiratory Research - April 23, 2016 Category: Respiratory Medicine Authors: Kim A. A. Schilders, Evelien Eenjes, Sander van Riet, André A. Poot, Dimitrios Stamatialis, Roman Truckenmüller, Pieter S. Hiemstra and Robbert J. Rottier Source Type: research

Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study
Asthma is a biologically heterogeneous disease and development of novel therapeutics requires understanding of pathophysiologic phenotypes. There is uncertainty regarding the stability of clinical characterist... (Source: Respiratory Research)
Source: Respiratory Research - April 23, 2016 Category: Respiratory Medicine Authors: P. E. Silkoff, M. Laviolette, D. Singh, J. M. FitzGerald, S. Kelsen, V. Backer, C. Porsbjerg, P. O. Girodet, P. Berger, J. N. Kline, S. Khatri, P. Chanez, V. S. Susulic, E. S. Barnathan, F. Baribaud and M. J. Loza Source Type: research

Surgical treatment of choanal atresia with transnasal endoscopic approach with stentless single side-hinged flap technique: 5 year retrospective analysis
Conclusions The surgical technique described follows the basic requirements of corrective surgery and allows good visualization, evaluation and treatment of the atretic plate and the posterior third of the septum, in order to create the new choanal opening. We think that the use of a stent is not necessary, as recommended in case of other surgical techniques involving the use of more mucosal flaps. (Source: Brazilian Journal of Otorhinolaryngology)
Source: Brazilian Journal of Otorhinolaryngology - April 23, 2016 Category: ENT & OMF Source Type: research

Design and engineering of a man-made diffusive electron-transport protein
This article is part of a Special Issue entitled Biodesign for Bioenergetics — the design and engineering of electronic transfer cofactors, proteins and protein networks, edited by Ronald L. Koder and J.L. Ross Anderson. (Source: Biochimica et Biophysica Acta (BBA) Bioenergetics)
Source: Biochimica et Biophysica Acta (BBA) Bioenergetics - April 23, 2016 Category: Biochemistry Source Type: research

Assessment of respiratory flow cycle morphology in patients with chronic heart failure
Abstract Breathing pattern as periodic breathing (PB) in chronic heart failure (CHF) is associated with poor prognosis and high mortality risk. This work investigates the significance of a number of time domain parameters for characterizing respiratory flow cycle morphology in patients with CHF. Thus, our primary goal is to detect PB pattern and identify patients at higher risk. In addition, differences in respiratory flow cycle morphology between CHF patients (with and without PB) and healthy subjects are studied. Differences between these parameters are assessed by investigating the following three classificatio...
Source: Medical and Biological Engineering and Computing - April 23, 2016 Category: Biomedical Engineering Source Type: research

Frequency of obstructive sleep apnea (OSA) in patients with gastroesophageal reflux disease (GERD) and the effect of nasal continuous positive airway pressure
Conclusion (1) A high risk for OSA development is more frequent in GERD patients especially NERD ones and who experience nighttime symptoms, (2) there is a mutual relationship between OSA and GERD reinforcing each other, and (3) CPAP therapy has a good role in the treatment of both OSA and GERD symptoms. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - April 23, 2016 Category: Respiratory Medicine Source Type: research

Correlation of high resolution CT patterns with pulmonary function tests in patients with interstitial lung diseases
Conclusion HRCT patterns and degree of lung involvement of ILDs correlate with pulmonary function parameters. Lung volumes are lower in fibrotic lesion regardless the degree of lung involvement, while DLCO among different patterns were dependent upon the degree of lung involvement. Restrictive pulmonary dysfunction correlate with gas exchange in fibrotic pattern while in ground glass one, gas exchange is independent on lung volumes. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - April 23, 2016 Category: Respiratory Medicine Source Type: research

Critical Care Updates for the Nephrologist, 2016
Publication date: May 2016 Source:Advances in Chronic Kidney Disease, Volume 23, Issue 3 Author(s): Xosé L. Pérez, Kathleen D. Liu With improvements in supportive care, mortality from sepsis and the acute respiratory distress syndrome has declined over the past 20 years. However, mortality associated with these conditions is still high. We will review the latest clinical trial findings in these fields, along with implications for the nephrologist. Very recently, there have been significant changes with regard to the management of anterior ischemic strokes; given the high rate of cerebrovascular disease in patients w...
Source: Advances in Chronic Kidney Disease - April 23, 2016 Category: Urology & Nephrology Source Type: research

Extracorporeal Membrane Oxygenation—What the Nephrologist Needs to Know
Publication date: May 2016 Source:Advances in Chronic Kidney Disease, Volume 23, Issue 3 Author(s): Andres Oswaldo Razo-Vazquez, Kevin Thornton Extracorporeal membrane oxygenation (ECMO) use in adults is rapidly increasing in its use for both cardiac and respiratory failure. ECMO exists in 2 primary configurations: veno-venous ECMO, used in the setting of isolated respiratory failure, and veno-arterial ECMO, which can be used in respiratory failure but is mandatory in the setting of cardiac failure. Acute kidney injury occurs frequently in patients on ECMO, and renal replacement therapy is often required. Continuous fo...
Source: Advances in Chronic Kidney Disease - April 23, 2016 Category: Urology & Nephrology Source Type: research

The history of respiratory disease management
Lung diseases have shifted from infections – tuberculosis, pneumonia – to diseases of dirty air – chronic obstructive pulmonary disease, asthma and lung cancer. New diseases have emerged from industrial pollution and HIV, while better imaging has revealed others previously unrecognized. Scientific advances in microbiology, imaging and clinical measurement have improved diagnosis and allowed better targeted treatment. Advances in treatment have been dramatic, the most important being drugs (antibiotics, cortisone, β2-adrenoreceptor agonists), ventilatory support (from iron lung to nasal positive-pressure ventilation)...
Source: Medicine - April 23, 2016 Category: Internal Medicine Authors: Duncan Geddes Tags: Infection Source Type: research

Morbidity and Mortality among Patients with Respiratory Syncytial Virus Infection: A Two-Year Retrospective Review
Previous studies have demonstrated high morbidity and mortality for adult patients with respiratory syncytial virus (RSV) infection. We performed a retrospective, multicenter, two-year chart review of all patients (n=334) testing positive for RSV by the ProFlu+® Influenza A/B and RSV assay (Hologic, Bedford, MA). We analyzed indicators of morbidity and mortality in children < 6 years old, immunocompetent and immunosuppressed adults, and transplant patients. Significant morbidity and mortality was observed among hematopoietic stem cell transplant patients (7.3%, 60-day mortality), solid organ transplant patients (13.3%, 60...
Source: Diagnostic Microbiology and Infectious Disease - April 23, 2016 Category: Microbiology Authors: Neil W. Anderson, Matthew J. Binnicker, Dana M. Harris, Razvan M. Chirila, Lisa Brumble, Jay Mandrekar, D. Jane Hata Source Type: research

First report of Metastrongylus pudendotectus by the genetic characterization of mitochondria genome of cox1 in pigs from Tibet, China
Publication date: Available online 22 April 2016 Source:Veterinary Parasitology Author(s): Kun Li, Houqiang Luo, Hui Zhang, Yanfang Lan, Zhaoqing Han, Muhammad Shahzad, Xiaoqiang Wang, Gang Qiu, Shucheng Huang, Wenteng Jiang, Jiakui Li Lungworms, a world wild distributed parasites cause serious respiratory diseases to the pigs. A high infection rate of Metastrongylus lungworms has been found in Tibetan pigs being slaughtered in different slaughter houses of Tibet autonomous region. The main aim of our study was to detect and confirm the lungworm parasite by the genetic characterization of mitochondrial cox1gen...
Source: Veterinary Parasitology - April 23, 2016 Category: Veterinary Research Source Type: research

Ventilation-Induced Brain Injury in Preterm Neonates: A Review of Potential Therapies.
Abstract Mechanical ventilation is a risk factor for cerebral inflammation and brain injury in preterm neonates. The risk increases proportionally with the intensity of treatment. Recent studies have shown that cerebral inflammation and injury can be initiated in the delivery room. At present, initiation of intermittent positive pressure ventilation (IPPV) in the delivery room is one of the least controlled interventions a preterm infant will likely face. Varying pressures and volumes administered shortly after birth are sufficient to trigger pathways of ventilation-induced lung and brain injury. The pathways invol...
Source: Neonatology - April 23, 2016 Category: Perinatology & Neonatology Authors: Barton SK, Tolcos M, Miller SL, Christoph-Roehr C, Schmölzer GM, Moss TJ, Hooper SB, Wallace EM, Polglase GR Tags: Neonatology Source Type: research

Surgical Necrotizing Enterocolitis versus Spontaneous Intestinal Perforation in White Matter Injury on Brain Magnetic Resonance Imaging.
CONCLUSION: In preterm infants at less than 32 weeks of gestation, those with surgNEC showed more severe WMI than infants with SIP on brain MRI at TEA. PMID: 27105356 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - April 23, 2016 Category: Perinatology & Neonatology Authors: Shin SH, Kim EK, Yoo H, Choi YH, Kim S, Lee BK, Jung YH, Kim HY, Kim HS, Choi JH Tags: Neonatology Source Type: research

Paroxysmal cold hemoglobinuria in a child with RSV: An under recognized cause of hemolytic anemia
We present the case of a previously healthy boy found to have respiratory syncytial virus (RSV) and severe anemia due to PCH. This case report will highlight key features that may raise clinical suspicion for this diagnosis and provide guidance for diagnostic testing and management. (Source: The American Journal of Emergency Medicine)
Source: The American Journal of Emergency Medicine - April 23, 2016 Category: Emergency Medicine Authors: Claritsa Santos Malavé, Deborah L. Shardy, S. Kate Hartman, Esther M. Sampayo Source Type: research

Active Screening and Surveillance in the United Kingdom for Middle East Respiratory Syndrome Coronavirus in returning travellers and pilgrims from the Middle East - a prospective descriptive study for the period 2013- 2015.
(Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - April 23, 2016 Category: Infectious Diseases Authors: Sowsan F Atabani, Steven Wilson, Clare Overton-Lewis, Judith Workman, I. Michael Kidd, Eskild Petersen, Alimuddin Zumla, Erasmus Smit, Husam Osman Source Type: research

Mycobacterium tuberculosis strain 18b, a useful non-virulent streptomycin dependent mutant to study latent tuberculosis as well as for in vivo and in vitro testing of anti-tuberculosis drugs
Mycobacterium tuberculosis (Mtb) strain 18b was isolated in 1955 by Hashimoto [1] from a patient with pulmonary tuberculosis (TB) caused by a streptomycin resistant strain of Mtb. However, the drug resistance was later found to be consequent to a mutation that generated a streptomycin dependent mutant. The mutant was incapable of growing in Lowenstein-Jensen medium containing less than 40μg/ml of streptomycin but maintained its viability in vitro for several weeks in the absence of the antibiotic. (Source: Tuberculosis)
Source: Tuberculosis - April 23, 2016 Category: Respiratory Medicine Authors: Antonio Campos-Neto Tags: Letter to the Editor Source Type: research

Comorbid conditions are associated with healthcare utilization, medical charges and mortality of patients with rheumatoid arthritis
This study aims to examine the associations between comorbid conditions and healthcare utilization, medical charges, or mortality of patients with rheumatoid arthritis (RA). Nebraska state emergency department (ED) discharge, hospital discharge, and death certificate data from 2007 to 2012 were used to study the comorbid conditions of patients with RA. RA was defined using the standard International Classification of Diseases (ICD-9-CM 714 or ICD-10-CM M05, M06, and M08). There were more comorbid conditions in patients with RA than in patients without RA. Comorbid conditions were majorly related to healthcare utilization a...
Source: Clinical Rheumatology - April 23, 2016 Category: Rheumatology Source Type: research

Secukinumab: A New Treatment Option for Psoriatic Arthritis
Conclusion Secukinumab offers an effective new addition to the available treatment options for PsA. Regulatory submissions have been filed worldwide, with the first approvals recently obtained in Japan and Europe. Future studies are required to define the optimal timing and strategic use of this novel treatment modality. Funding Novartis Pharma. (Source: Rheumatology and Therapy)
Source: Rheumatology and Therapy - April 23, 2016 Category: Rheumatology Source Type: research

Number of Ribs Resected is Associated with Respiratory Complications Following Lobectomy with en bloc Chest Wall Resection
Conclusions In patients undergoing lobectomy with en bloc chest wall resection for non-small cell lung cancer, the number of ribs resected is directly associated with incidence of postoperative respiratory complications. (Source: Lung)
Source: Lung - April 23, 2016 Category: Respiratory Medicine Source Type: research

Platelet Indices in Patients with Coal Workers’ Pneumoconiosis
Conclusions Platelet indices may be considered as disease markers for pneumoconiosis in coal miners and as a useful indicator of the progression of pneumoconiosis. (Source: Lung)
Source: Lung - April 23, 2016 Category: Respiratory Medicine Source Type: research

Functionalized porous silica&maghemite core-shell nanoparticles for applications in medicine: design, synthesis, and immunotoxicity.
CONCLUSIONS: The cytotoxicity and in vitro immunotoxicity were found to be minimal in the newly developed porous core-shell γ-Fe2O3&SiO2-NH2 magnetic nanoparticles. PMID: 27106358 [PubMed - in process] (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - April 23, 2016 Category: Journals (General) Authors: Zasonska BA, Líškova A, Kuricova M, Tulinska J, Pop-Georgievski O, Čiampor F, Vavra I, Dušinska M, Ilavska S, Horvathova M, Horák D Tags: Croat Med J Source Type: research

Phrenic motor outputs in response to bronchopulmonary C-fibre activation following chronic cervical spinal cord injury.
This article is protected by copyright. All rights reserved. PMID: 27106483 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - April 23, 2016 Category: Physiology Authors: Lee KZ Tags: J Physiol Source Type: research

Denitratimonas tolerans gen. nov., sp. nov., a denitrifying bacterium isolated from a bioreactor for tannery wastewater treatment.
Abstract A denitrifying bacterium, designated strain E4-1(T), was isolated from a bioreactor for tannery wastewater treatment, and its taxonomic position was investigated using a polyphasic approach. Strain E4-1(T), a facultative anaerobic bacterium, was observed to grow between 0 and 12 % (w/v) NaCl, between pH 3.0 and 12.0. Cells were found to be oxidase-positive and catalase-negative. Phylogenetic analyses based on 16S rRNA gene sequences showed that strain E4-1(T) forms a distinct lineage with respect to closely related genera in the family Xanthomonadaceae, and is closely related to Chiayiivirga, Aquimonas an...
Source: Antonie van Leeuwenhoek - April 23, 2016 Category: Microbiology Authors: Han SI, Kim JO, Lee YR, Ekpeghere KI, Koh SC, Whang KS Tags: Antonie Van Leeuwenhoek Source Type: research

Dual infections of equine herpesvirus 1 and equine arteritis virus in equine respiratory mucosa explants.
Abstract Equine herpesvirus 1 (EHV-1) and equine arteritis virus (EAV) induce respiratory problems and abortion in horses and are considered as two serious threats to equine industry. Both EHV-1 and EAV misuse patrolling leukocytes in the upper respiratory tract to breach the basement membrane (BM) and to migrate to blood vessels. So far, the behavior and impact of a double infection in the respiratory mucosa of a horse are unknown. In the present study, the outcome of double infections with EHV-1 and the low virulent EAV strain 08P187 (superinfection with an interval of 12h or co-infection) were compared with sing...
Source: Virus Research - April 23, 2016 Category: Virology Authors: Zhao J, Negussie H, Laval K, Poelaert K, Nauwynck HJ Tags: Virus Res Source Type: research

In vitro modeling of the interaction between human epithelial cells and lymphocytes upon influenza infection
This article is protected by copyright. All rights reserved. (Source: Influenza and Other Respiratory Viruses)
Source: Influenza and Other Respiratory Viruses - April 22, 2016 Category: Virology Authors: Natalia A. Ilyushina, Peter F. Wright Tags: Short Article Source Type: research

The role of inspiratory muscle training in the management of asthma and exercise-induced bronchoconstriction.
Authors: Shei RJ, Paris HL, Wilhite DP, Chapman RF, Mickleborough TD Abstract Asthma is a pathological condition comprising of a variety of symptoms which affect the ability to function in daily life. Due to the high prevalence of asthma and associated healthcare costs, it is important to identify low-cost alternatives to traditional pharmacotherapy. One of these low cost alternatives is the use of inspiratory muscle training (IMT), which is a technique aimed at increasing the strength and endurance of the diaphragm and accessory muscles of respiration. IMT typically consists of taking voluntary inspirations agains...
Source: The Physician and Sportsmedicine Online - April 22, 2016 Category: Sports Medicine Tags: Phys Sportsmed Source Type: research

Surgical Necrotizing Enterocolitis versus Spontaneous Intestinal Perforation in White Matter Injury on Brain Magnetic Resonance Imaging
Conclusion: In preterm infants at less than 32 weeks of gestation, those with surgNEC showed more severe WMI than infants with SIP on brain MRI at TEA.Neonatology 2016;110:148-154 (Source: Neonatology)
Source: Neonatology - April 22, 2016 Category: Perinatology & Neonatology Source Type: research

Ventilation-Induced Brain Injury in Preterm Neonates: A Review of Potential Therapies
Mechanical ventilation is a risk factor for cerebral inflammation and brain injury in preterm neonates. The risk increases proportionally with the intensity of treatment. Recent studies have shown that cerebral inflammation and injury can be initiated in the delivery room. At present, initiation of intermittent positive pressure ventilation (IPPV) in the delivery room is one of the least controlled interventions a preterm infant will likely face. Varying pressures and volumes administered shortly after birth are sufficient to trigger pathways of ventilation-induced lung and brain injury. The pathways involved in ventilatio...
Source: Neonatology - April 22, 2016 Category: Perinatology & Neonatology Source Type: research

Pulmonary Cytomegalovirus Replication in Renal Transplant Patients with Late Onset Pneumonitis.
CONCLUSIONS Our findings suggest that pulmonary CMV replication occurs in renal transplant patients with pneumonitis even at later phases after renal transplantation. This finding seems to be a frequent complication (7/25 patients). Clinicians should be aware of this condition because blood-based screening assays for CMV will remain negative. PMID: 27097869 [PubMed - in process] (Source: Annals of Transplantation)
Source: Annals of Transplantation - April 22, 2016 Category: Transplant Surgery Authors: Königshausen E, Hengel H, Adams O, Bry H, Steiner S, Priegnitz C, Hansen A, Sellin L, Rump LC, Voiculescu A Tags: Ann Transplant Source Type: research

Comparison of Energy Expenditure During Single-Set vs. Multiple-Set Resistance Exercise
Abstract: Mookerjee, S, Welikonich, MJ, and Ratamess, NA. Comparison of energy expenditure during single-set vs. multiple-set resistance exercise. J Strength Cond Res 30(5): 1447–1452, 2016—The purpose of this study was to compare energy expenditure (EE) of single-set and multiple-set resistance exercise protocols using indirect calorimetry. Twelve men and twelve women (age = 21.4 ± 1.3 years) performed a single-set (SS) and multiple-set (MS) resistance exercise protocol in random order. The subjects performed two protocols at 70% of their 1-repetition maximum. The protocols consisted of 5 upper-body exercises of eith...
Source: Journal of Strength and Conditioning Research - April 22, 2016 Category: Sports Medicine Tags: Original Research Source Type: research

Association between menarche and increased bronchial hyper‐responsiveness during puberty in female children and adolescents
ConclusionBHR declined with age in the Korean pediatric population. A younger age and reduced lung function were common factors related to BHR in both genders. Additionally, atopy was related to BHR in males, whereas sexual maturation was related to BHR in females. These findings have important clinical implications for evaluating of childhood BHR and asthma related to gender. Pediatr Pulmonol.. © 2016 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - April 22, 2016 Category: Respiratory Medicine Authors: Young‐Ho Kim, Eun Lee, Hyun‐Ju Cho, Song‐I Yang, Young‐Ho Jung, Hyung Young Kim, Ju‐Hee Seo, Hyo‐Bin Kim, So‐Yeon Lee, Dae‐Jin Song, Woo‐Kyung Kim, Gwang‐Cheon Jang, Jung‐Yeon Shim, Eun‐Jin Kim, Joo‐Shil Lee, Ji‐Won Kwon, Soo Tags: Original Article Source Type: research

Vitamin D Deficiency Is Associated with Rapid Decline in Exercise Capacity in Male Patients with Chronic Obstructive Pulmonary Disease
Conclusion: This study shows that vitamin D deficiency is associated with rapid decline in exercise capacity in male patients with COPD.Respiration (Source: Respiration)
Source: Respiration - April 22, 2016 Category: Respiratory Medicine Source Type: research

Azithromycin may prevent severe respiratory-infection-induced wheezing
Bacharier LB, Guilbert TW, Mauger DT, Boehmer S, Beigelman A, Fitzpatrick AM, et al. Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. JAMA 2015;314:2034-44. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - April 22, 2016 Category: Pediatrics Authors: Kirsten M. Kloepfer Tags: Current Best Evidence Source Type: research

FOXF1 maintains endothelial barrier function and prevents edema after lung injury.
Abstract Multiple signaling pathways, structural proteins, and transcription factors are involved in the regulation of endothelial barrier function. The forkhead protein FOXF1 is a key transcriptional regulator of embryonic lung development, and we used a conditional knockout approach to examine the role of FOXF1 in adult lung homeostasis, injury, and repair. Tamoxifen-regulated deletion of bothFoxf1alleles in endothelial cells of adult mice (Pdgfb-iCreER/Foxf1(-/-)) caused lung inflammation and edema, leading to respiratory insufficiency and death. Deletion of a singleFoxf1allele made heterozygousPdgfb-iCreER/Foxf...
Source: Science Signaling - April 22, 2016 Category: Biomedical Science Authors: Cai Y, Bolte C, Le T, Goda C, Xu Y, Kalin TV, Kalinichenko VV Tags: Sci Signal Source Type: research