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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 18.

Simvastatin in the Acute Respiratory Distress Syndrome
New England Journal of Medicine, Volume 0, Issue 0, Ahead of Print. (Source: New England Journal of Medicine)
Source: New England Journal of Medicine - October 1, 2014 Category: Internal Medicine Tags: article Source Type: research

Tidal Volume and Plateau Pressure Use for Acute Lung Injury From 2000 to Present: A Systematic Literature Review*
Conclusions: For clinicians treating acute lung injury since 2000, achieving VT less than or equal to 6 mL/kg predicted body weight may not have been as attainable or important as PPlat less than or equal to 30 cm H2O. If so, there may be equipoise to test if VT less than or equal to 6 mL/kg predicted body weight are necessary to improve acute lung injury outcome. (Source: Critical Care Medicine)
Source: Critical Care Medicine - October 1, 2014 Category: Emergency Medicine Tags: Review Article Source Type: research

Underuse Versus Equipoise for Low Tidal Volume Ventilation in Acute Respiratory Distress Syndrome: Is This the Right Question?*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - October 1, 2014 Category: Emergency Medicine Tags: Editorials Source Type: research

Activation of Hypoxia-Inducible Factor-1α in Type 2 Alveolar Epithelial Cell Is a Major Driver of Acute Inflammation Following Lung Contusion*
Conclusion: Activation of hypoxia-inducible factor-1α in type 2 cell is a major driver of acute inflammation following lung contusion. (Source: Critical Care Medicine)
Source: Critical Care Medicine - October 1, 2014 Category: Emergency Medicine Tags: Online Laboratory Investigations Source Type: research

Coronaviruses: severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus in travelers
Purpose of reviewMiddle East respiratory syndrome coronavirus (MERS-CoV) is currently the focus of global attention. In this review, we describe virological, clinical, epidemiological features and interim travel advice and guidelines regarding MERS-CoV. We compare and contrast these with the severe acute respiratory syndrome coronavirus (SARS-CoV). Recent findingsMERS-CoV is a novel β CoV that causes a spectrum of clinical illness from asymptomatic to the rapidly fatal disease mainly in those with comorbid conditions. Epidemiological and genomic studies show zoonotic transmission to humans from camels and possibly bats. I...
Source: Current Opinion in Infectious Diseases - October 1, 2014 Category: Infectious Diseases Tags: TROPICAL AND TRAVEL-ASSOCIATED DISEASES: Edited by Joseph M. Vinetz and Yukari C. Manabe Source Type: research

The evidence for symptomatic treatments in amyotrophic lateral sclerosis
Discussion focuses predominantly on recently published articles. We cover management settings, disease-modifying treatment, vitamin D, respiratory management including noninvasive ventilation and diaphragmatic pacing, secretions, nutrition, dysphagia and gastrostomy, communication problems, mobility, spasticity, pain, cognition, depression and emotional lability, fatigue, sleep disturbance, head drop, prevention of deep venous thrombosis and end-of-life issues. Summary: Multidisciplinary specialist care appears to improve quality of life and survival. Riluzole remains the only available disease-modifying medication and con...
Source: Current Opinion in Neurology - October 1, 2014 Category: Neurology Tags: NERVE, NEURO-MUSCULAR JUNCTION AND MOTOR NEURON DISEASES: Edited by Kevin Talbot and Angela Vincent Source Type: research

Clinical and scientific aspects of muscle-specific tyrosine kinase-related myasthenia gravis
Purpose of review: Antibodies to muscle-specific tyrosine kinase (MuSK) characterize up to 5% of myasthenia gravis patients. This review focuses on the differences to clinical antiacetylcholine receptor-myasthenia gravis, and on the physiology and animal studies that elucidate the role of MuSK and help explain the clinical disease. Recent findings: MuSK forms the core of a protein complex in the postsynaptic membrane at the neuromuscular junction. During development, MuSK tyrosine kinase signaling is vital for the formation and stabilization of the postsynaptic endplate; it is now clear that long-term homeostasis of mature...
Source: Current Opinion in Neurology - October 1, 2014 Category: Neurology Tags: NERVE, NEURO-MUSCULAR JUNCTION AND MOTOR NEURON DISEASES: Edited by Kevin Talbot and Angela Vincent Source Type: research

Chronic obstructive pulmonary disease and the risk for ventilator-associated pneumonia
Purpose of reviewTo discuss recent data on the relationship between chronic obstructive pulmonary disease (COPD) and ventilator-associated pneumonia (VAP). Recent findingsDespite increased use of noninvasive ventilation, a large proportion of COPD patients still require invasive mechanical ventilation. Intubated COPD patients are at increased risk for VAP compared with patients without COPD. VAP is associated with increased mortality and duration of mechanical ventilation in these patients. Specific risk factors for VAP in this population include prolonged duration of invasive mechanical ventilation, high incidence of micr...
Source: Current Opinion in Critical Care - October 1, 2014 Category: Nursing Tags: INFECTIOUS DISEASES: Edited by Michael S. Niederman Source Type: research

Zinc deficiency and toxicity in pediatric practice
Purpose of reviewZinc is a commonly overlooked deficiency in developed countries, occurring in infants, children, and adolescents during critical growth periods. The purpose of this review is to present the evidence of zinc deficiencies and toxicities as well as treatment in pediatrics. Recent findingsDuring the last decade, the significance of zinc deficiency in childhood growth, morbidity, and mortality has been recognized by a number of large-scale supplementation trials in underdeveloped countries. Recognition of the recent nationwide shortage of injectable zinc available for total parenteral nutrition supplementation ...
Source: Current Opinion in Pediatrics - October 1, 2014 Category: Pediatrics Tags: GASTROENTEROLOGY AND NUTRITION: Edited by Robert Wyllie Source Type: research

Limiting acute respiratory distress syndrome in the emergency department: a survey of US academic emergency medicine physicians
No abstract available (Source: European Journal of Emergency Medicine)
Source: European Journal of Emergency Medicine - October 1, 2014 Category: Emergency Medicine Tags: Correspondence Source Type: research

Intensive Care Unit Admission in Children With Malignant or Nonmalignant Disease: Incidence, Outcome, and Prognostic Factors: A Single-Center Experience
Objective:To investigate pediatric intensive care unit (PICU) admission in children with malignant and nonmalignant diseases who developed life-threatening complications. Patients and Methods:Between 1999 and 2010, of the 1278 eligible pediatric patients treated for a malignant or nonmalignant disease, 54 were admitted to the PICU for respiratory distress (40.7%), neurological events (33.3%), severe sepsis (14.8%), and organ failure (11.2%). Results:Rate of PICU admission was 4.2%, with a 2-year cumulative incidence of 4.5%. Risk factors associated with higher cumulative incidence of PICU admission were older age at study ...
Source: Journal of Pediatric Hematology Oncology - October 1, 2014 Category: Hematology Tags: Online Articles: Original Articles Source Type: research

Advanced Sclerosis of The Chest Wall Skin Secondary to Chronic Graft-versus-Host Disease: A Case With Severe Restrictive Lung Defect
In conclusion, pulmonary cGvHD can present with restrictive changes related with the advanced sclerosis of the chest wall skin. Performing a fasciotomy or a scar revision for the rigid chest wall in selected patients may improve the patients ventilation. (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - October 1, 2014 Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research

The Burden of Single Virus and Viral Coinfections on Severe Lower Respiratory Tract Infections Among Preterm Infants: A Prospective Birth Cohort Study in Brazil
Conclusions:This study confirms the association of RSV alone or as a coinfection with severe LRTI and reinforces the importance of providing adequate prophylaxis for susceptible infants. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2014 Category: Infectious Diseases Tags: Original Studies Source Type: research

Bronchiolitis and Pneumonia Requiring Hospitalization in Young First Nations Children in Northern Ontario, Canada
We examined rates of LRTI in First Nations Canadian infants living in the Sioux Lookout Zone, in Northern Ontario. Methods:A retrospective review of hospital admissions for LRTI during a 5-year period, in patients (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - October 1, 2014 Category: Infectious Diseases Tags: Original Studies Source Type: research

Respiratory Artifact on EEG Independent of the Respirator
Abstract:Recognizing EEG artifacts is important to correctly interpret and avoid unnecessary intervention. EEG artifacts from mechanical ventilation have been described as periodic, frontally maximal high amplitude waveforms, occurring at the same rate as the ventillator. Here, we describe a non-periodic respiratory artifact that was independent of the ventilator rate. The concomitant use of audio was helpful in identifying this artifact. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - October 1, 2014 Category: Neurology Tags: Case Report Source Type: research

Monitoring Sedation in Patients Receiving Opioids for Pain Management
Excessive sedation precedes opioid-induced respiratory depression. An evidence-based practice project standardized systematic sedation monitoring by nurses using an opioid sedation scale and respiratory assessment when opioids are administered for pain management. Nurses were educated and documentation updated. Nurses demonstrated increased ability to identify at-risk patients (3.2 pre-implementation; 3.6 post-implementation; 1-4 Likert scale) and reported understanding the tool to assess for oversedation (2.6 pre-implementation; 3.2 post-implementation). Documentation compliance improved, and patient safety was maintained...
Source: Journal of Nursing Care Quality - October 1, 2014 Category: Nursing Tags: Articles Source Type: research

Seronegative granulomatous polyangiitis with central retinal artery occlusion as the initial manifestation
Conclusion:Granulomatous polyangiitis is a multisystem vasculitic disorder. Central retinal artery occlusion as the presenting manifestation of GP is very uncommon. This report demonstrates the difficulty of diagnosing GP, particularly when initial diagnostic assays (including both serology and biopsy) were negative for GP. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - October 1, 2014 Category: Opthalmology Tags: Pacific Retina Club: Case Report Source Type: research

Multiple bilateral branch retinal artery occlusions in a patient with sickle cell disease with vancomycin red man syndrome
Conclusion:Retinal artery occlusion is a rare but potentially devastating complication of sickle cell disease. The potential for complications from vancomycin infusion during acute sickle crisis should be considered, although further study is warranted. (Source: Retinal Cases and Brief Reports)
Source: Retinal Cases and Brief Reports - October 1, 2014 Category: Opthalmology Tags: Pacific Retina Club: Case Report Source Type: research

Quantitative High-Resolution Renal Perfusion Imaging Using 3-Dimensional Through-Time Radial Generalized Autocalibrating Partially Parallel Acquisition
ConclusionsHighly undersampled data were successfully reconstructed with 3D through-time radial GRAPPA to achieve a high-resolution 3-dimensional renal DCE-MRI examination. The acquisition was completely free breathing, and the images were registered to compensate for respiratory motion. This allowed for an accurate high-resolution 3D quantitative renal functional mapping of perfusion and filtration parameters. (Source: Investigative Radiology)
Source: Investigative Radiology - October 1, 2014 Category: Radiology Tags: Original Articles Source Type: research

Relationship Between Serum Leptin and Chronic Obstructive Pulmonary Disease in US Adults: Results From the Third National Health and Nutrition Examination Survey
ConclusionsWe did not find any significant difference in the levels of serum leptin in subjects with COPD. Our data provide indirect evidence against a major role for serum leptin in the pathogenesis of COPD in humans. (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - October 1, 2014 Category: Research Tags: Original Articles Source Type: research

Hypoxic Training: Effect on Mitochondrial Function and Aerobic Performance in Hypoxia
Conclusions: Our data suggest that, in moderately trained subjects, 6 wk of hypoxic training possesses no ergogenic effect at sea level. It is not excluded that hypoxic training might facilitate endurance capacity at moderate altitude; however, this issue is still open and needs to be further examined. (Source: Medicine and Science in Sports and Exercise)
Source: Medicine and Science in Sports and Exercise - October 1, 2014 Category: Sports Medicine Tags: Basic Sciences Source Type: research

Physiological Responses to Diesel Exhaust Exposure Are Modified by Cycling Intensity
Conclusions: Respiratory and metabolic responses to low-intensity, but not high-intensity, cycling in DE exceed FA. Practically, the greater responses during low-intensity exercise in DE could have implications for individuals with cardiopulmonary disease. Also, the elevated RPE during DE could impair performance in self-paced exercise. (Source: Medicine and Science in Sports and Exercise)
Source: Medicine and Science in Sports and Exercise - October 1, 2014 Category: Sports Medicine Tags: Applied Sciences Source Type: research

Plasmatic isoforms of cytokeratin 18 and RAGE after severe trauma: A longitudinal cohort study
CONCLUSIONThe release of RAGE (but not cytokeratin 18) isoforms occurs early and transiently after trauma and is associated with the extent of injury and inflammatory response. RAGE and cytokeratin 18 isoforms have the potential to act as diagnostic or prognostic biomarkers of lung and hepatic dysfunction. LEVEL OF EVIDENCEEpidemiologic/prognostic study, level IV. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - October 1, 2014 Category: Surgery Tags: Original Articles Source Type: research

Ventilator Use, Respiratory Problems, and Caregiver Well-Being in Korean Patients With Amyotrophic Lateral Sclerosis Receiving Home-Based Care
Conclusion: On the basis of the findings of this study, care management for patients with ALS with a home-based ventilator as well as their caregiver’s well-being was relatively inappropriate. We recommend that community-based support programs and burden relief programs be considered as managerial interventions. (Source: Journal of Neuroscience Nursing)
Source: Journal of Neuroscience Nursing - October 1, 2014 Category: Neuroscience Tags: Article Source Type: research

A Randomized Controlled Trial of the Efficacy and Respiratory Effects of Patient-Controlled Intravenous Remifentanil Analgesia and Patient-Controlled Epidural Analgesia in Laboring Women
No abstract available (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - October 1, 2014 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

A Retrospective Assessment of the Incidence of Respiratory Depression After Neuraxial Morphine Administration for Postcesarean Delivery Analgesia
No abstract available (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - October 1, 2014 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

Phase II Multicenter Clinical Trial of Pulmonary Metastasectomy and Isolated Lung Perfusion with Melphalan in Patients with Resectable Lung Metastases
Conclusion:Compared with historical series of PM resection without ILuP, favorable results are obtained in terms of local control without long-term adverse effects. These data support the further investigation of ILuP as additional treatment in patients with resectable PM from CRC or sarcoma. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 1, 2014 Category: Cancer & Oncology Tags: Original Articles Source Type: research

Robin Sequence: Mortality, Causes of Death, and Clinical Outcomes
Conclusions: Mortality and negative quality-of-life measures in Robin sequence are not directly related to respiratory obstruction. Isolated Robin sequence confers no increased risk of mortality. There is a high incidence of cardiac and central nervous system anomalies, which are significantly associated with mortality. Cardiac and cranial imaging should be performed during the initial evaluation of infants with Robin sequence. CLINICAL QUESTION/LEVEL OF EVIDENCE: Risk, III. (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - October 1, 2014 Category: Cosmetic Surgery Tags: Pediatric/Craniofacial: Original Articles Source Type: research

Respiratory Secretion Analyses in the Evaluation of Ventilator-Associated Pneumonia: A Survey of Current Practice in Pediatric Critical Care*
Conclusions: The majority of pediatric intensivists would obtain respiratory secretion cultures and Gram stains in the evaluation of an intubated child with fever and leukocytosis and initiate antibiotics guided by the results. The specificity of respiratory secretion cultures and Gram stains for the diagnosis of ventilator-associated pneumonia requires critical evaluation as this diagnosis is responsible for more than half of antibiotic use in the PICU. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - October 1, 2014 Category: Pediatrics Tags: Feature Articles Source Type: research

Fatalities Above 30,000 Feet: Characterizing Pediatric Deaths on Commercial Airline Flights Worldwide*
Conclusions: Pediatric in-flight fatalities are rare, but death occurs most commonly in infants and in subjects with a preexisting medical condition. The number of fatalities involving seemingly previously healthy children under the age of 2 years (lap infants) is intriguing and could indicate a vulnerable population at increased risk of death related to in-flight environmental factors, sleeping arrangements, or yet another unrecognized factor. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - October 1, 2014 Category: Pediatrics Tags: Online Brief Report Source Type: research

The Effects of Different Oxygen Concentrations on Recruitment Maneuver During General Anesthesia for Laparoscopic Surgery
In this study, we aimed to determine the effects of different oxygen concentrations during RM on the arterial oxygenation and respiration mechanics in laparoscopic cases. Materials and Methods:Thirty-two patients undergoing laparoscopic cholecystectomy were recruited into the study. The patients were randomly divided into 2 groups. RM with a 30% oxygen concentration was performed in patients within the first group (group I, n=16), whereas patients in the second group (group II, n=16) received RM with 100% oxygen. To study respiratory mechanics, dynamic compliance (Cdyn), airway resistance (Raw), and peak inspiratory pressu...
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - October 1, 2014 Category: Surgery Tags: Original Articles Source Type: research

Effect of a Smoking Ban on Respiratory Health in Nonsmoking Hospitality Workers: A Prospective Cohort Study
Conclusions: The below-average lung function before the smoking ban indicates chronic damages from long-term exposure. Respiratory symptoms such as cough decreased within 12 months after the ban. (Source: Journal of Occupational and Environmental Medicine)
Source: Journal of Occupational and Environmental Medicine - October 1, 2014 Category: Occupational Health Tags: Original Articles Source Type: research

ALS and Other Motor Neuron Diseases
This article also covers other motor neuron diseases, reviews how to distinguish them from ALS, and discusses their pathophysiology. Recent Findings:In this article, the spectrum of cognitive involvement in ALS, new concepts about protein synthesis pathology in the etiology of ALS, and new genetic associations will be covered. This concept has changed over the past 3 to 4 years with the discovery of new genes and genetic processes that may trigger the disease. As of 2014, two-thirds of familial ALS and 10% of sporadic ALS can be explained by genetics. TAR DNA binding protein 43 kDa (TDP-43), for instance, has been shown to...
Source: CONTINUUM - October 1, 2014 Category: Neurology Tags: Review Articles Source Type: research

Maintenance Tocolysis With Oral Micronized Progesterone for Prevention of Preterm Birth After Arrested Preterm Labor
ABSTRACT: Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. The accepted treatment of preterm labor is acute tocolysis, but whether maintenance tocolysis is appropriate after initial tocolysis for spontaneous preterm labor is uncertain. Progesterone has not been thoroughly investigated for use to maintain tocolysis. This double-blind, randomized, placebo-controlled trial was undertaken to evaluate the efficacy of maintenance therapy with oral micronized progesterone (OMP) for prolongation of pregnancy in parturients with arrested preterm labor. Women at 24 to 34 weeks’ gestation with a sin...
Source: Obstetrical and Gynecological Survey - October 1, 2014 Category: OBGYN Tags: Obstetrics: Obstetrical Complications Source Type: research

Pieces to the Puzzle of Endobronchial Valve Insertion for Emphysema
No abstract available (Source: Journal of Bronchology and Interventional Pulmonology)
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Editorial Source Type: research

Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: Indian Perspective
No abstract available (Source: Journal of Bronchology and Interventional Pulmonology)
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Perspective Source Type: research

The IBV Valve Trial: A Multicenter, Randomized, Double-Blind Trial of Endobronchial Therapy for Severe Emphysema
Conclusions:This trial had technical and statistical success but partial-bilateral endobronchial valve occlusion did not obtain clinically meaningful results. Safety results were acceptable and compare favorably to lung volume reduction surgery and other bronchial valve studies. Further studies need to focus on improved patient selection and a different treatment algorithm. Trial Registry:ClinicalTrials.gov NCT00475007. (Source: Journal of Bronchology and Interventional Pulmonology)
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Original Investigations Source Type: research

Endosonography for the Diagnosis of Malignant Lymphoma Presenting With Mediastinal Lymphadenopathy
Conclusions:On the basis of these data, we conclude that endosonography is a minimally invasive, safe, and sensitive method for the assessment of recurrent mediastinal malignant lymphoma or alternative diagnoses but has limitations in assessing a primary lymphoma diagnosis. (Source: Journal of Bronchology and Interventional Pulmonology)
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Original Investigations Source Type: research

Impact of Pleural Manometry on the Development of Chest Discomfort During Thoracentesis: A Symptom-based Study
Conclusions:In our retrospective study, the use of manometry did not appear to anticipate the development of chest discomfort during therapeutic thoracentesis. Prospective studies are needed to confirm these findings. (Source: Journal of Bronchology and Interventional Pulmonology)
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Original Investigations Source Type: research

Construct Validity of the Simbionix Bronch Mentor Simulator for Essential Bronchoscopic Skills
Background:Although simulation-based bronchoscopy has been shown to be an effective training modality, formal assessment should still be performed as new technology emerges. We sought to validate a simulator in essential bronchoscopic tasks, and survey perceptions of bronchoscopists on simulation. Methods:A cohort study at 2 medical centers used 3 groups to assess construct validity of the Simbionix Bronchoscopy Simulator: 7 first-year fellows with 1000 bronchoscopies each (expert). Participants were tested in 4 tasks (1: scope manipulation, 2: guided anatomic navigation, 3: airway anatomy, and 4: lymph node anatomy). Part...
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Original Investigations Source Type: research

Enhancement of Conventional TBNA Outcome After EBUS Training
The objective our study was to compare the outcomes of C-TBNA before and after the implementation of EBUS in our unit. Methods:We compared the diagnostic performance of C-TBNA in 2 groups of non–small cell lung cancer patients with mediastinal lymph nodes >10 mm in short axis as seen on the computed tomography scan of the chest. Patients underwent C-TBNA before (group A, N=147) or after (group B, N=67) implementing EBUS technology in our unit. C-TBNA technique was performed by the same bronchoscopists before and after being proficient in EBUS. Results:The overall accuracy in group B was higher than in group A (23.9% vs. ...
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Original Investigations Source Type: research

Matrix Metalloproteinase-9 Expression in Lung Cancer Patients and Its Relation to Serum MMP-9 Activity, Pathologic Type, and Prognosis
Background:Matrix metalloproteinase-9 is closely associated with the invasive and metastatic potential of most types of solid cancers. Our objective was to investigate the MMP-9 expression in lung cancer and to evaluate their relations to histopathologic types and prognosis. Methods:Bronchoscopic samples were obtained from tumor and normal bronchial mucosa in 25 patients with lung cancer. Total RNA was isolated from the tissues, and the relative expression as well as the activity of MMP-9 was evaluated. Results:Non–small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) showed significantly higher MMP-9 expressi...
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Original Investigations Source Type: research

Large Pleural Nodules Secondary to Mycobacterium tuberculosis
We present images from a patient with less commonly seen large pleural nodules and plaques resulting from tuberculous pleuritis. (Source: Journal of Bronchology and Interventional Pulmonology)
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Images in Interventional Pulmonology Source Type: research

Posterior Tracheal Diverticulosis
Multiple tracheal diverticulosis is a rare clinical entity. Tracheal diverticula are usually recognized radiologically as solitary right paratracheal air collections on thoracic computed tomography examination. They are usually asymptomatic but can occasionally present with persistent symptoms. We herein report the case of a 50-year-old male patient who underwent extensive evaluation for persistent cough. Multiple posterior right paratracheal air collections were recognized on thoracic multidetector computed tomography examination, which was confirmed as multiple-acquired posterior upper tracheal diverticula on flexible br...
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Images in Interventional Pulmonology Source Type: research

Double Lung Transplantation for Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare cause of obstructive lung disease and a proposed precursor of pulmonary carcinoid tumors. With increased awareness of this disease, an accumulating number of cases have been reported. Patients may have progressive shortness of breath due to small airway obstruction. There is limited information on treatment of the disease, particularly for those with progressive disease. Here we report 2 patients who were treated at our institution with double lung transplantation. Both patients were female nonsmokers with a clinical presentation of cough and ...
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Case Reports Source Type: research

Intrabronchial Valves for Treatment of Alveolar-Pleural Fistula in a Patient With Pneumocystis jirovecii Pneumonia
We report a case of a patient with alveolo-pleural fistula secondary to Pneumocystis jirovecii pneumonia who was successfully treated with the use of intrabronchial unidirectional valves inserted using flexible bronchoscopy. (Source: Journal of Bronchology and Interventional Pulmonology)
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Case Reports Source Type: research

Pseudo-tumor Mimicking Indwelling Pleural Catheter Tract Metastasis in Mesothelioma
We report 2 patients with mesothelioma who developed new subcutaneous nodules at their indwelling pleural catheter insertion site, mimicking tract metastases. Biopsies of both lesions revealed benign etiologies and both resolved without requiring irradiation. These cases remind clinicians that new subcutaneous lesions can be benign even when arising at pleural puncture sites of malignant pleural mesothelioma patients. Percutaneous biopsy can clarify the diagnosis in suitable cases. (Source: Journal of Bronchology and Interventional Pulmonology)
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Case Reports Source Type: research

Primary Endobronchial Histiocytic Sarcoma in a Case of Papillary Carcinoma Thyroid: A Complex Clinical Scenario
Histiocytic sarcoma is a rare malignant neoplasm showing histiocytic differentiation. We document a case of a 55-year-old man presenting with cough and breathlessness following a subtotal thyroidectomy for infiltrating papillary thyroid carcinoma. An endobronchial growth was seen on endoscopy. Histopathologic examination revealed a neoplasm of histiocytic lineage with positivity for leucocyte common antigen, Vimentin, CD68, CD4, and CD45RO. To the best of our knowledge, primary endobronchial histiocytic sarcoma in association with infiltrating papillary thyroid carcinoma has not been reported in the literature so far. Our ...
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Case Reports Source Type: research

Complex Metallic Stent Removal: Decade After Deployment
We present a case of longstanding endobronchial GPA with recurrent bronchial stenosis. Three SEMs were deployed in the distal left main bronchus 10 years prior. Two were removed in the standard manner, but the remaining stent SEM was completely embedded in the bronchial mucosa making its removal extraordinarily difficult. We placed an oversized silicone stent inside the stent leading to necrosis of the mucosa allowing for a less formidable removal of the embedded stent. Another silicone stent was temporarily placed. SEMs removal can be extremely complicated and should only be performed by experienced bronchoscopists in an ...
Source: Journal of Bronchology and Interventional Pulmonology - October 1, 2014 Category: Respiratory Medicine Tags: Brief Reports Source Type: research