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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 18.

Early Psychological Therapy in Critical Illness
Semin Respir Crit Care Med 2016; 37: 136-142DOI: 10.1055/s-0035-1570367Survivors of critical illness often experience long-lasting impairments in mental, cognitive, and physical functioning. Acute stress reactions and delusional memories appear to play an important role in psychological morbidity following critical illness, and few interventions exist to address these symptoms. This review elucidates acute psychological stressors experienced by the critically ill. The effects of psychological stress and state of mind on disease are discussed using examples from the non–intensive care unit (ICU) literature, including a re...
Source: Seminars in Respiratory and Critical Care Medicine - January 28, 2016 Category: Respiratory Medicine Authors: Karnatovskaia, Lioudmila V.Philbrick, Kemuel L.Parker, Ann M.Needham, Dale M. Source Type: research

Erratum to: Asbestos-Related Lung Cancer and Malignant Mesothelioma of the Pleura: Selected Current Issues (Semin Respir Crit Care Med 2015;36(3):334–346)
Semin Respir Crit Care Med 2016; 37: 143-144DOI: 10.1055/s-0035-1570120Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Full text (Source: Seminars in Respiratory and Critical Care Medicine)
Source: Seminars in Respiratory and Critical Care Medicine - January 28, 2016 Category: Respiratory Medicine Authors: Markowitz, Steven Tags: Erratum Source Type: research

Pleural disease in infants and children: management updates
This article addresses new treatments for congenital hydrothorax and chylothorax, parapneumonic effusions, and spontaneous pneumothoraces in children. Invasive fetal surgical methods to drain pleural fluid in utero improve survival and reduce the chance of postnatal pulmonary hypoplasia. Video-assisted thoracoscopic surgery and intrapleural instillation of fibrinolytic agents produce similar outcomes for children with empyema and/or parapneumonic effusions. Spontaneous primary pneumothoraces in older children and young adults are increasingly treated with drainage methods that prevent or reduce hospitalizations. Newer trea...
Source: Current Respiratory Care Reports - January 28, 2016 Category: Respiratory Medicine Source Type: research

Microglia PACAP and glutamate: Friends or foes in seizure-induced autonomic dysfunction and SUDEP?
Publication date: Available online 26 January 2016 Source:Respiratory Physiology & Neurobiology Author(s): Amol M. Bhandare, Komal Kapoor, Melissa M.J. Farnham, Paul M. Pilowsky Seizure-induced cardiorespiratory autonomic dysfunction is a major cause of sudden unexpected death in epilepsy (SUDEP), and the underlying mechanism is unclear. Seizures lead to increased synthesis, and release of glutamate, pituitary adenylate cyclase activating polypeptide (PACAP), and other neurotransmitters, and cause extensive activation of microglia at multiple regions in the brain including central autonomic cardiorespiratory ...
Source: Respiratory Physiology and Neurobiology - January 28, 2016 Category: Respiratory Medicine Source Type: research

Understanding COPD: A vision on phenotypes, comorbidities and treatment approach
Publication date: Available online 27 January 2016 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): E. Fragoso, S. André, J.P. Boleo-Tomé, V. Areias, J. Munhá, J. Cardoso Chronic Obstructive Pulmonary Disease (COPD) phenotypes have become increasingly recognized as important for grouping patients with similar presentation and/or behavior, within the heterogeneity of the disease. The primary aim of identifying phenotypes is to provide patients with the best health care possible, tailoring the therapeutic approach to each patient. However, the identification of specific phenotypes has been hin...
Source: Revista Portuguesa de Pneumologia - January 28, 2016 Category: Respiratory Medicine Source Type: research

Abel Ayerza
Publication date: Available online 28 January 2016 Source:The Lancet Respiratory Medicine Author(s): Priya Venkatesan (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - January 28, 2016 Category: Respiratory Medicine Source Type: research

NICE guidance on nintedanib for treating idiopathic pulmonary fibrosis
Publication date: Available online 27 January 2016 Source:The Lancet Respiratory Medicine Author(s): Sophie Laurenson, Raisa Sidhu, Melinda Goodall, Amanda I Adler (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - January 28, 2016 Category: Respiratory Medicine Source Type: research

Moderate exercise attenuated airway resistance and inflammation induced by cigarette smoke solution and endotoxin in rats
Conclusions We demonstrated that 2 weeks of treadmill exercise improved airway resistance and diaphragm muscle contractile force in rats exposed to repetitive CSS plus endotoxin. We propose that local inflammation was attenuated by aerobic exercise, which increased diaphragm muscle contractility. (Source: Sport Sciences for Health)
Source: Sport Sciences for Health - January 28, 2016 Category: Sports Medicine Source Type: research

Infusoabdomen with Abdominal Compartment in Extremely Low Birth Weight Neonates
Conclusion The 2 cases reveal that the displacement of a PICC can occur without direct clinical signs of hemodynamic imbalance i.e. bleeding or hematoma. Displacement of the catheter tip from intra-vascular, retro-peritoneal position can cause abdominal compartment syndromes either via trans-peritoneal migration of fluids or after perforation of the peritoneum via intra-abdominal administration of given infusion. Both options caused life threatening complications. Watchfulness and intensive surgical and non-surgical care are indicated to handle these severe complications. (Source: Journal of Pediatric Surgery Case Reports)
Source: Journal of Pediatric Surgery Case Reports - January 28, 2016 Category: Surgery Source Type: research

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2
The protease HtrA2 has a protective role inside mitochondria, but promotes apoptosis under stress. We previously identified the G399S HtrA2 mutation in Parkinson's disease (PD) patients and reported mitochondrial dysfunction in vitro. Mitochondrial dysfunction is a common feature of PD and related to neurodegeneration. Complete loss of HtrA2 has been shown to cause neurodegeneration in mice. However, the full impact of HtrA2 overexpression or the G399S mutation is still to be determined in vivo. Here, we report the first HtrA2 G399S transgenic mouse model. Our data suggest that the mutation has a dominant-negative effect. ...
Source: Human Molecular Genetics - January 28, 2016 Category: Genetics & Stem Cells Authors: Casadei, N., Sood, P., Ulrich, T., Fallier-Becker, P., Kieper, N., Helling, S., May, C., Glaab, E., Chen, J., Nuber, S., Marcus, K., Rapaport, D., Ott, T., Riess, O., Krüger, R., Fitzgerald, J. C. Tags: ARTICLES Source Type: research

The exome sequencing identified the mutation in YARS2 encoding the mitochondrial tyrosyl-tRNA synthetase as a nuclear modifier for the phenotypic manifestation of Leber's hereditary optic neuropathy-associated mitochondrial DNA mutation
Leber's hereditary optic neuropathy (LHON) is the most common mitochondrial disorder. Nuclear modifier genes are proposed to modify the phenotypic expression of LHON-associated mitochondrial DNA (mtDNA) mutations. By using an exome sequencing approach, we identified a LHON susceptibility allele (c.572G>T, p.191Gly>Val) in YARS2 gene encoding mitochondrial tyrosyl-tRNA synthetase, which interacts with m.11778G>A mutation to cause visual failure. We performed functional assays by using lymphoblastoid cell lines derived from members of Chinese families (asymptomatic individuals carrying m.11778G>A mutation, or bot...
Source: Human Molecular Genetics - January 28, 2016 Category: Genetics & Stem Cells Authors: Jiang, P., Jin, X., Peng, Y., Wang, M., Liu, H., Liu, X., Zhang, Z., Ji, Y., Zhang, J., Liang, M., Zhao, F., Sun, Y.-H., Zhang, M., Zhou, X., Chen, Y., Mo, J. Q., Huang, T., Qu, J., Guan, M.-X. Tags: ARTICLES Source Type: research

Identification of protein–protein interactions between the TatB and TatC subunits of the twin-arginine translocase system and respiratory enzyme specific chaperones
Publication date: Available online 28 January 2016 Source:Biochimica et Biophysica Acta (BBA) - Biomembranes Author(s): Lalita Kuzniatsova, Tara M.L. Winstone, Raymond J. Turner The Twin-arginine translocation (Tat) pathway serves for translocation of fully folded proteins across the cytoplasmic membrane in bacterial and chloroplast thylakoid membranes. The Escherichia coli Tat system consists of three core components: TatA, TatB, and TatC. The TatB and TatC subunits form the receptor complex for Tat dependent proteins. The TatB protein is composed of a single transmembrane helix and cytoplasmic domain. The structure ...
Source: Biochimica et Biophysica Acta (BBA) Biomembranes - January 28, 2016 Category: Biochemistry Source Type: research

Respiration in spiders (Araneae)
Abstract Spiders (Araneae) are unique regarding their respiratory system: they are the only animal group that breathe simultaneously with lungs and tracheae. Looking at the physiology of respiration the existence of tracheae plays an important role in spiders with a well-developed tracheal system. Other factors as sex, life time, type of prey capture and the high ability to gain energy anaerobically influence the resting and the active metabolic rate intensely. Most spiders have metabolic rates that are much lower than expected from body mass; but especially those with two pairs of lungs. Males normally have highe...
Source: Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology - January 28, 2016 Category: Physiology Source Type: research

Epidemiology and risk factors for nosocomial bloodstream infections in solid organ transplants over a 10‐year period
ConclusionsThis study demonstrates the common sources, risk factors, and causative organisms of BSI, which can guide empiric antibiotic choices, and highlights areas where preventative interventions could be targeted to prevent nosocomial BSI in SOT.This article is protected by copyright. All rights reserved. (Source: Transplant Infectious Disease)
Source: Transplant Infectious Disease - January 28, 2016 Category: Transplant Surgery Authors: B.M. Berenger, K. Doucette, S.W. Smith Tags: Original Report Source Type: research

Diagnostic Accuracy of PCR Alone and Compared to Urinary Antigen Testing for Detection of Legionella spp.: a Systematic Review [Bacteriology]
The diagnosis of Legionnaires' disease (LD) is based on the isolation of Legionella spp., a 4-fold rise in antibodies, a positive urinary antigen (UA), or direct immunofluorescence tests. PCR is not accepted as a diagnostic tool for LD. This systematic review assesses the diagnostic accuracy of PCR in various clinical samples with a direct comparison versus UA. We included prospective or retrospective cohort and case-control studies. Studies were included if they used the Centers for Disease Control and Prevention consensus definition criteria of LD or a similar one, assessed only patients with clinical pneumonia, and repo...
Source: Journal of Clinical Microbiology - January 28, 2016 Category: Microbiology Authors: Avni, T., Bieber, A., Green, H., Steinmetz, T., Leibovici, L., Paul, M. Tags: Bacteriology Source Type: research

BioFire FilmArray Respiratory Panel for Detection of Enterovirus D68 [Virology]
During the enterovirus D68 (EV-D68) outbreak of 2014, the BioFire FilmArray (FA) respiratory panel was used to detect rhinovirus/enterovirus in respiratory specimens; suspected EV-D68-positive specimens were sent to CDC for confirmation. Positive rhinovirus/enterovirus FA targets revealed patterns loosely associated with EV-D68 that may be useful for confirmation triaging. (Source: Journal of Clinical Microbiology)
Source: Journal of Clinical Microbiology - January 28, 2016 Category: Microbiology Authors: Shibib, D. R., Matushek, S. M., Beavis, K. G., Gawel, S. H., Charnot-Katsikas, A. Tags: Virology Source Type: research

Effect of calf purchase and other herd-level risk factors on mortality, unwanted early slaughter, and use of antimicrobial group treatments in Swiss veal calf operations
The objective of this survey was to determine herd level risk factors for mortality, unwanted early slaughter, and metaphylactic application of antimicrobial group therapy in Swiss veal calves in 2013. A questionnaire regarding farm structure, farm management, mortality and antimicrobial use was sent to all farmers registered in a Swiss label program setting requirements for improved animal welfare and sustainability. Risk factors were determined by multivariable logistic regression. A total of 619 veal producers returned a useable questionnaire (response rate=28.5%), of which 40.9% only fattened their own calves (group O)...
Source: Preventive Veterinary Medicine - January 28, 2016 Category: Veterinary Research Source Type: research

European molecular epidemiology and strain diversity of feline calicivirus
Feline calicivirus (FCV) causes a variable syndrome of upper respiratory tract disease, mouth ulcers and lameness. A convenience-based prospective sample of oropharyngeal swabs (n=426) was obtained from five countries (France, Germany, Greece, Portugal and the UK). The prevalence of FCV by virus isolation was 22.2 per cent. Multivariable analysis found that animals presenting with lymphoplasmacytic gingivitis stomatitis complex were more likely to test positive for FCV infection. Furthermore, vaccinated cats up to 48 months of age were significantly less likely to be infected with FCV than unvaccinated animals of simi...
Source: Veterinary Record - January 28, 2016 Category: Veterinary Research Authors: Hou, J., Sanchez-Vizcaino, F., McGahie, D., Lesbros, C., Almeras, T., Howarth, D., O'Hara, V., Dawson, S., Radford, A. D. Tags: Open access Research Source Type: research

Consumption of Bifidobacterium animalis subsp. lactis BB‐12 impacts upper respiratory tract infection and the function of NK and T cells in healthy adults
ConclusionThe timing of BB‐12 addition to yogurt smoothies in relation to the fermentation process influenced the impact of BB‐12 on immune function and cold/flu severity in young healthy adults.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 28, 2016 Category: Food Science Authors: Huicui Meng, Yujin Lee, Zhaoyong Ba, Jiayu Peng, Junli Lin, Alexander S. Boyer, Jennifer A. Fleming, Emily J. Furumoto, Robert F. Roberts, Penny M. Kris‐Etherton, Connie J. Rogers Tags: Research Article Source Type: research

Barium concentration in cast roe deer antlers related to air pollution caused by burning of barium-enriched coals in southern Poland.
Abstract Concentrations of Ba, Zn, Pb, Fe, and Mn were determined by atomic absorption spectroscopy in freshly cast antlers from male roe deer of different ages (2 to 4 years old and older than 4 years) collected in Balin near Chrzanów and in the vicinity of Żywiec, S Poland. Barium content ranged from 124 to 196 ppm (mean 165 ppm) in the Balin 12 samples and from 207 to 351 ppm (mean 287 ppm) in 3 antlers from Żywiec. The concentration of Ba was comparable to that of Zn (134-275 ppm, mean 169 ppm). Elevated concentrations of Ba in antlers most probably originated from direct uptake of airborne barite na...
Source: Environmental Science and Pollution Research International - January 28, 2016 Category: Environmental Health Authors: Jabłońska M, Kramarczyk M, Smieja-Król B, Janeczek J Tags: Environ Sci Pollut Res Int Source Type: research

Analysis and Characterization of Staphylococcus aureus Small Colony Variants Isolated From Cystic Fibrosis Patients in Austria.
This study revealed rather low SCV ratios in CF patients compared to other countries. PMID: 26821237 [PubMed - as supplied by publisher] (Source: Current Microbiology)
Source: Current Microbiology - January 28, 2016 Category: Microbiology Authors: Masoud-Landgraf L, Zarfel G, Kaschnigg T, Friedl S, Feierl G, Wagner-Eibel U, Eber E, Grisold AJ, Kittinger C Tags: Curr Microbiol Source Type: research

Effect of Cocaine on Pulmonary Vascular Remodeling and Hemodynamics in HIV-transgenic Rats.
In conclusion, our findings support an additive effect of cocaine and HIV on smooth muscle dysfunction resulting in enhanced pulmonary vascular remodeling with associated elevation of mPAP and RVSP in HIV-Tg rats exposed to cocaine. PMID: 26820592 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - January 28, 2016 Category: Molecular Biology Authors: Dalvi P, Spikes L, Allen J, Gupta VG, Sharma H, Gillcrist M, Montes de Oca J, O' Brien-Ladner A, Dhillon NK Tags: Am J Respir Cell Mol Biol Source Type: research

Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging.
Abstract Alterations in mitochondrial bioenergetics have been associated with brain aging. In order to evaluate the susceptibility of brain cortex synaptosomes and non-synaptic mitochondria to aging-dependent dysfunction, male Swiss mice of 3 or 17 months old were used. Mitochondrial function was evaluated by oxygen consumption, mitochondrial membrane potential and respiratory complexes activity, together with UCP-2 protein expression. Basal respiration and respiration driving proton leak were decreased by 26 and 33 % in synaptosomes from 17-months old mice, but spare respiratory capacity was not modified by agin...
Source: Neurochemical Research - January 28, 2016 Category: Neuroscience Authors: Lores-Arnaiz S, Lombardi P, Karadayian AG, Orgambide F, Cicerchia D, Bustamante J Tags: Neurochem Res Source Type: research

A randomized Phase III trial of thoracoscopic versus open esophagectomy for thoracic esophageal cancer: Japan Clinical Oncology Group Study JCOG1409
A randomized Phase III study was commenced in May 2015 to confirm the non-inferiority of thoracoscopic esophagectomy to open esophagectomy in terms of overall survival for clinical Stage I–III esophageal cancer. A total of 300 patients will be accrued from Japanese institutions over 6 years. The primary endpoint is overall survival. The secondary endpoints are relapse-free survival, proportion of patients with R0 resection, proportion of patients who underwent re-operation, adverse events, postoperative respiratory function change, postoperative quality-of-life score (EORTC QLQ-C30), and proportion of patients who ne...
Source: Japanese Journal of Clinical Oncology - January 28, 2016 Category: Cancer & Oncology Authors: Kataoka, K., Takeuchi, H., Mizusawa, J., Ando, M., Tsubosa, Y., Koyanagi, K., Daiko, H., Matsuda, S., Nakamura, K., Kato, K., Kitagawa, Y., on behalf of the Japan Esophageal Oncology Group/Japan Clinical Oncology Group Tags: Clinical Trial Note Source Type: research

Management of Hyperleukocytosis
Opinion statement Hyperleukocytosis has a high morbidity index. The involvement of the respiratory or central nervous system and the metabolic derangements accompanying tumor lysis are responsible for early mortality. Standard care for acute hyperleukocytosis must include cytoreduction, proper supportive care, and prevention of tumor lysis. Hydration, alkalization, allopurinol, or urate oxidase should be started immediately. In patients with low platelet count of less than 20,000/mm3, platelet transfusions should be given to prevent cerebral hemorrhage, as platelets do not add substantially to blood viscosity. Pa...
Source: Current Treatment Options in Oncology - January 28, 2016 Category: Cancer & Oncology Source Type: research

Obesity is associated with decreased lung compliance and hypercapnia during robotic assisted surgery
In conclusion, patients’ physical status, especially obesity, represents the main risk factor for decreased lung compliance during RAS and patient positioning in either Trendelenburg or steep Trendelenburg during surgery has limited effects on respiratory physiology. (Source: Journal of Clinical Monitoring and Computing)
Source: Journal of Clinical Monitoring and Computing - January 28, 2016 Category: Information Technology Source Type: research

Mitochondrial DNA Depletion in Respiratory Chain–Deficient Parkinson Disease Neurons
ObjectiveTo determine the extent of respiratory chain abnormalities and investigate the contribution of mtDNA to the loss of respiratory chain complexes (CI–IV) in the substantia nigra (SN) of idiopathic Parkinson disease (IPD) patients at the single‐neuron level. MethodsMultiple‐label immunofluorescence was applied to postmortem sections of 10 IPD patients and 10 controls to quantify the abundance of CI–IV subunits (NDUFB8 or NDUFA13, SDHA, UQCRC2, and COXI) and mitochondrial transcription factors (TFAM and TFB2M) relative to mitochondrial mass (porin and GRP75) in dopaminergic neurons. To assess the involvement o...
Source: Annals of Neurology - January 28, 2016 Category: Neurology Authors: Anne Grünewald, Karolina A. Rygiel, Philippa D. Hepplewhite, Christopher M. Morris, Martin Picard, Doug M. Turnbull Tags: Research Article Source Type: research

Developmental nicotine exposure alters cholinergic control of respiratory frequency in neonatal rats
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - January 28, 2016 Category: Neurology Authors: Lila B. Wollman, Jarl Haggerty, Jason Q. Pilarski, Richard B. Levine, Ralph F. Fregosi Tags: Research Article Source Type: research

Developmental Nicotine Exposure disrupts dendritic arborization patterns of hypoglossal motoneurons in the neonatal rat
This study was undertaken to test the hypothesis that these functional consequences of DNE are accompanied by changes in the dendritic morphology of hypoglossal motoneurons. Hypoglossal motoneurons in brain stem slices were filled with neurobiotin during whole‐cell patch clamp recordings and subjected to histological processing to reveal dendrites. Morphometric analysis, including the Sholl method, revealed significant effects of DNE on dendritic branching patterns. In particular, whereas within the first 5 postnatal days there was significant growth of the higher‐order dendritic branches of motoneurons from control an...
Source: Journal of Neurobiology - January 28, 2016 Category: Neurology Authors: Gregory L. Powell, Joshua Gaddy, Fei Xu, Ralph F. Fregosi, Richard B. Levine Tags: Research Article Source Type: research

Selected Engineering and Physicochemical Aspects of Systemic Drug Delivery by Inhalation.
Abstract Inhalation of aerosolized pharmaceuticals is a non-invasive and convenient method of drug delivery typically used for local treatment of lung diseases. Large absorption area of the pulmonary region opens up the possibility of fast and effective transfer of inhaled medicines to the circulation in order to obtain systemic effects. This review is devoted to selected albeit essential challenges of targeting aerosolized drugs to the blood via the pulmonary part of the respiratory system. The special attention is given to some physicochemical aspects of drug formulation which are essential for overcoming the air...
Source: Current Pharmaceutical Design - January 28, 2016 Category: Drugs & Pharmacology Authors: Sosnowski TR Tags: Curr Pharm Des Source Type: research

Respiratory support for preterm infants – the Cochrane evidence and beyond
Respiratory failure is the commonest morbidity of newborn infants, often necessitating support. While respiratory support of newborn infants is life-saving, it is strongly associated with long-term sequelae. Modes of support for newborn infants, especially preterm infants, have been evolving over the last four decades. Key developments have ensured improvement in survival and outcomes of these vulnerable infants. A large body of evidence has been collected on the appropriate respiratory management of preterm newborn infants. (Source: Paediatrics and Child Health)
Source: Paediatrics and Child Health - January 28, 2016 Category: Pediatrics Authors: Christopher Course, Mallinath Chakraborty Tags: Symposium: neonatology Source Type: research

Control of influenza infection is impaired by diminished interferon-γ secretion by CD4 T cell in the lungs of toddlers.
This study highlights the intrinsic limitations in CD4 T cell effector functions that may arise in toddlers and contribute to disease pathology. PMID: 26823488 [PubMed - as supplied by publisher] (Source: Journal of Leukocyte Biology)
Source: Journal of Leukocyte Biology - January 28, 2016 Category: Hematology Authors: Verhoeven D, Perry S, Pryharski K Tags: J Leukoc Biol Source Type: research

The Pivotal Role of AKAP121 in Mitochondrial Physiology.
Abstract In this Perspective, we discuss some recent developments in the study of the mitochondrial scaffolding protein AKAP121 (also known as AKAP1, or AKAP149 as the human homolog), with an emphasis on its role in mitochondrial physiology. AKAP121 has been identified to function as a key regulatory molecule in several mitochondrial events including oxidative phosphorylation, the control of membrane potential, fission-induced apoptosis, maintenance of mitochondrial Ca(2+) homeostasis and the phosphorylation of various mitochondrial respiratory chain substrate molecules. Furthermore, we discuss the role of hypoxia ...
Source: Am J Physiol Cell Ph... - January 28, 2016 Category: Cytology Authors: Czachor A, Failla A, Lockey R, Kolliputi N Tags: Am J Physiol Cell Physiol Source Type: research

Diversity and severity of adverse reactions to quinine: A systematic review
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - January 28, 2016 Category: Hematology Authors: Nathan W. Liles, Evaren E. Page, Amber L. Liles, Sara K. Vesely, Gary E. Raskob, James N. George Tags: Research Article Source Type: research

Reversible airway obstruction in cystic fibrosis: Common, but not associated with characteristics of asthma
As asthma-like symptoms are common in CF, we evaluated reversible airway obstruction and associated characteristics. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - January 28, 2016 Category: Respiratory Medicine Authors: Hagit Levine, Malena Cohen-Cymberknoh, Nitai Klein, Moshe Hoshen, Huda Mussaffi, Patrick Stafler, Oded Breuer, Eitan Kerem, Hannah Blau Tags: Original Article Source Type: research

Linking mobile source-PAHs and biological effects in traffic police officers and drivers in Rawalpindi (Pakistan).
Abstract The aim of this study was to evaluate the effect of traffic related polycyclic aromatic hydrocarbons (PAHs) on blood parameters of subjects, including traffic police officers (TP), drivers (DR) and control subjects (CN) with presumably different levels of exposure. We quantified the urinary 1-hydroxypyrene (1-OHPyr), α-naphthol and β-naphthol (α- and β-naph) as biomarkers of exposure to PAHs in relation with biomarkers of effect (Hb, MCV, PCV, PLT, RBCs), biomarkers of inflammation/infection (CRP, WBCs), oxidative stress (SOD) and oxidative DNA damage i.e. 8-hydroxy-2-deoxyguanosine (8-OHdG). Results s...
Source: Ecotoxicology and Environmental Safety - January 28, 2016 Category: Environmental Health Authors: Kamal A, Cincinelli A, Martellini T, Malik RN Tags: Ecotoxicol Environ Saf Source Type: research

Predictors of 1-Year Survival After Endovascular Aneurysm Repair.
CONCLUSION: Personalised 1-year survival risk enables surgeons and patients to consider seriously the risks and benefits of EVAR prior to surgery. PMID: 26831928 [PubMed - as supplied by publisher] (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - January 28, 2016 Category: Surgery Authors: Fitridge RA, Boult M, de Loryn T, Cowled P, Barnes M Tags: Eur J Vasc Endovasc Surg Source Type: research

Benign tracheal stenosis should never be stented with metallic devices.
PMID: 26830373 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - January 28, 2016 Category: Respiratory Medicine Authors: Varela G, Jiménez MF Tags: Arch Bronconeumol Source Type: research

Cluster of atypical adult Guillain-Barré syndrome temporally associated with neurological illness due to EV-D68 in children, South Wales, United Kingdom, October 2015 to January 2016.
We report a cluster of atypical Guillain-Barré syndrome in 10 adults temporally related to a cluster of four children with acute flaccid paralysis, over a 3-month period in South Wales, United Kingdom. All adult cases were male, aged between 24 and 77 years. Seven had prominent facial diplegia at onset. Available electrophysiological studies showed axonal involvement in five adults. Seven reported various forms of respiratory disease before onset of neurological symptoms. The ages of children ranged from one to 13 years, three of the four were two years old or younger. Enterovirus testing is available for three children; ...
Source: Euro Surveill - January 28, 2016 Category: Infectious Diseases Authors: Williams CJ, Thomas RH, Pickersgill TP, Lyons M, Lowe G, Stiff RE, Moore C, Jones R, Howe R, Brunt H, Ashman A, Mason BW Tags: Euro Surveill Source Type: research

A cluster of three cases of botulism due to Clostridium baratii type F, France, August 2015.
Abstract A cluster of three cases of food-borne botulism due to Clostridium baratii type F occurred in France in August 2015. All cases required respiratory assistance. Consumption of a Bolognese sauce at the same restaurant was the likely source of contamination. Clostridium baratii was isolated both from stool specimens from the three patients and ground meat used to prepare the sauce. This is the second episode reported in France caused by this rare pathogen. PMID: 26848055 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 28, 2016 Category: Infectious Diseases Authors: Tréhard H, Poujol I, Mazuet C, Blanc Q, Gillet Y, Rossignol F, Popoff MR, Jourdan Da Silva N Tags: Euro Surveill Source Type: research

Neonatal Extracorporeal Membrane Oxygenation: Update on Management Strategies and Long-Term Outcomes.
Abstract BACKGROUND: Extracorporeal membrane oxygenation (ECMO) can be deployed to support patients with severe cardiorespiratory failure unresponsive to conventional medical interventions. Neonatal trials have demonstrated that ECMO is an effective treatment of severe respiratory failure, with acceptable cognitive and functional outcomes. Technological advances in ECMO have resulted in improved safety and accessibility, contributing to decreased morbidity and improved survival of increasingly complex patients requiring ECMO support. PURPOSE: This review aims to describe the innovations in ECMO technology and m...
Source: Advances in Neonatal Care - January 27, 2016 Category: Nursing Authors: Mok YH, Lee JH, Cheifetz IM Tags: Adv Neonatal Care Source Type: research

Guest Editorial: Special Series in Respiratory Management.
PMID: 26808514 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - January 27, 2016 Category: Nursing Authors: Newnam KM Tags: Adv Neonatal Care Source Type: research

Epidemiology of Serotype 1 Invasive Pneumococcal Disease, South Africa, 2003-2013.
We describe the epidemiology of serotype 1 Streptococcus pneumoniae disease during the pre- and post-PCV eras (2003-2013). Using laboratory-based invasive pneumococcal disease (IPD) surveillance, we calculated annual incidences, identified IPD clusters, and determined serotype 1-associated factors. Of 46,483 IPD cases, 4,544 (10%) were caused by serotype 1. Two clusters of serotype 1 infection were detected during 2003-2004 and 2008-2012, but incidence decreased after 2011. Among children <5 years of age, those who had non-serotype 1 IPD had shorter hospital stays, fewer cases of penicillin-nonsusceptible disease, and l...
Source: Emerging Infectious Diseases - January 27, 2016 Category: Infectious Diseases Authors: von Mollendorf C, Cohen C, Tempia S, Meiring S, de Gouveia L, Quan V, Lengana S, Karstaedt A, Dawood H, Seetharam S, Lekalakala R, Madhi SA, Klugman KP, von Gottberg A, Group for Enteric, Respiratory, and Meningeal Disease Surveillance in South Africa (GE Tags: Emerg Infect Dis Source Type: research

Blastomyces gilchristii as Cause of Fatal Acute Respiratory Distress Syndrome.
We report molecular evidence of B. gilchristii as an etiologic agent of fatal acute respiratory distress syndrome. B. gilchristii infection was confirmed by PCR and sequence analysis. PMID: 26812599 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - January 27, 2016 Category: Infectious Diseases Authors: Dalcin D, Rothstein A, Spinato J, Escott N, Kus JV Tags: Emerg Infect Dis Source Type: research