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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 19.

A multi-analyte panel for non-invasive pharmacokinetic monitoring of second-line anti-tuberculosis drugs
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - June 12, 2016 Category: Respiratory Medicine Authors: Gerona, RoyWen, AnitaKoss, CatherineBacchetti, PeterGandhi, MonicaMetcalfe, John Source Type: research

Screening for active tuberculosis in a diabetes mellitus clinic in Soweto, South Africa
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - June 12, 2016 Category: Respiratory Medicine Authors: Majumder, AnweshaCarroll, BrynBhana, SindeepTefu, DorothySyeda, SbaaMartinson, NeilGolub, Jonathan Source Type: research

Errata
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - June 12, 2016 Category: Respiratory Medicine Source Type: research

Dexmedetomidine versus midazolam for sedation during endoscopy: A meta-analysis.
Authors: Zhang F, Sun HR, Zheng ZB, Liao R, Liu J Abstract Patients undergoing endoscopy frequently require sedation, which commonly includes the administration of midazolam or dexmedetomidine. Previous meta-analyses have mainly focused on comparing the effects of these two drugs in intensive care unit patients. In the present study, randomized controlled trials (RCTs) that compared the sedative and clinical effectiveness of these two drugs in patients undergoing endoscopy were searched in a number of databases. The meta-analysis showed that dexmedetomidine demonstrated a significantly lower rate of respiratory dep...
Source: Experimental and Therapeutic Medicine - June 12, 2016 Category: Journals (General) Tags: Exp Ther Med Source Type: research

Primary pulmonary synovial sarcoma presenting with a large lump mass in the left upper mediastinum: A case report.
Authors: Jiang AG, Yu H, Gao XY, Lu HY Abstract Primary pulmonary synovial sarcoma is a rare lesion that occurs in 0.5% cases of lung malignancies. Chest computed tomography (CT) reveals a heterogeneously enhancing mass in the lobe or hilum of the lungs, frequently calcified and with pleural invasion. Involvement of the mediastinum in the course of primary pulmonary synovial sarcoma, in particular detection of a large mass in the mediastinum as the sole initial imaging manifestation, is extremely rare, which may contribute to a delayed diagnosis or misdiagnosis. The present case report describes an extremely rare c...
Source: Experimental and Therapeutic Medicine - June 12, 2016 Category: Journals (General) Tags: Exp Ther Med Source Type: research

Role of oral propranolol in the treatment of infantile subglottic hemangioma.
CONCLUSION: Oral propranolol is a safe and effective treatment for infantile subglottic hemangiomata and may be used as a first-line therapeutic modality. PMID: 27285465 [PubMed - as supplied by publisher] (Source: International Journal of Clinical Pharmacology and Therapeutics)
Source: International Journal of Clinical Pharmacology and Therapeutics - June 12, 2016 Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research

Treatment outcome of new smear positive pulmonary tuberculosis patients in Hamadan, Iran: A registry-based cross-sectional study
Conclusion Treatment success rate in our study was 83.1%, which is slightly lower than the success target set by World Health Organization (WHO). Key determinants of poor treatment success rate, such as male gender, and not having hospitalization history during the treatment period, should be considered in efforts aimed to improve the treatment outcome in the management of TB. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - June 12, 2016 Category: Respiratory Medicine Source Type: research

Computed tomography-guided bronchoscopy in the diagnosis of small peripheral pulmonary lesions: A retrospective study of 240 examinations in a single academic center
Conclusions CT-guided bronchoscopy is valuable in the diagnosis of PPLs with positive CT-BS regardless of lesion size; however, PPLs with negative CT-BS are not good candidates for CT-guided bronchoscopy. Obtaining tissue specimens by biopsy is a critical factor in diagnosing PPLs. (Source: Respiratory Investigation)
Source: Respiratory Investigation - June 12, 2016 Category: Respiratory Medicine Source Type: research

Combination of virtual bronchoscopic navigation with conventional transbronchial needle aspiration in the diagnosis of peribronchial pulmonary lesions located in the middle third of the lungs
Conclusions The combination of VBN with conventional TBNA was advantageous and safe for the cytological diagnosis of small peribronchial pulmonary lesions in the middle third zone of the lungs. (Source: Respiratory Investigation)
Source: Respiratory Investigation - June 12, 2016 Category: Respiratory Medicine Source Type: research

Good news from the WHO
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - June 12, 2016 Category: Respiratory Medicine Authors: Davies, Peter D. Source Type: research

Serotonin in the solitary tract nucleus shortens the laryngeal chemoreflex in anaesthetized neonatal rats
New Findings What is the central question of this study? Failure to terminate apnoea and arouse is likely to contribute to sudden infant death syndrome (SIDS). Serotonin is deficient in the brainstems of babies who died of SIDS. Therefore, we tested the hypothesis that serotonin in the nucleus of the solitary tract (NTS) would shorten reflex apnoea. What is the main finding and its importance? Serotonin microinjected into the NTS shortened the apnoea and respiratory inhibition associated with the laryngeal chemoreflex. Moreover, this effect was achieved through a 5‐HT3 receptor. This is a new insight that is likely to b...
Source: Experimental Physiology - June 12, 2016 Category: Physiology Authors: William T. Donnelly, Donald Bartlett, J. C. Leiter Tags: Research Paper Source Type: research

Genetic Characterization of Human Bocavirus among Children with Severe Acute Respiratory Infection in China
To investigate the genetic character of Human bocavirus (HBoV) among children with severe acute respiratory infection (SARI) in China. (Source: Journal of Infection)
Source: Journal of Infection - June 12, 2016 Category: Infectious Diseases Authors: Yanqun Wang, Yamin Li, Jun Liu, Yanjie Zhao, Zhengde Xie, Jun Shen, Wenjie Tan Source Type: research

An Unusual Case of Disseminated Adenovirus Infection in a Cystic Fibrosis, Liver Transplant Patient
Adenovirus (AdV) is a common pediatric pathogen, most frequently affecting children under 5 years of age. AdV typically causes self-limited upper respiratory and gastrointestinal infections (GI), although ocular and urogenital infections have also been reported [1]. In addition, AdV is associated with the establishment of latency and prolonged asymptomatic shedding [1,2]. While improvements have been made regarding the prevention and control of many post-transplant infections, such as CMV, AdV infections still remain a challenge [3,4]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - June 12, 2016 Category: Virology Authors: Stephanie L. Mitchell, Adriana E. Kajon, Summer L. Kaplan, Jason Kim, Ana María Cárdenas Tags: Case report Source Type: research

[Smoking cessation support among persons in situation of precariousness].
CONCLUSIONS: Precarious smokers adhere to structured care with aid for access to TSN with a positive consequent impact on consumption. PMID: 27282327 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - June 11, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Breast metastases from lung cancers with the EGFR mutation].
CONCLUSION: In patients with lung adenocarcinoma and EGFR mutation, immunohistochemical examination, including TTF1 and genotyping of synchronous breast tumour, is needed to confirm its metastatic nature and to guide treatment. PMID: 27282326 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - June 11, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Outpatient thoracic surgery: Evolution of the indications, current applications and limits].
The objectives of outpatient surgery are to reduce the risks connected to hospitalization, to improve postoperative recovery and to decrease the health costs. Few studies have been performed in the field of thoracic surgery and there remains great scope for progress in outpatient lung surgery. The purpose of this article is to present a revue of the current situation and the prospects for the development of out patient thoracic surgery. PMID: 27282325 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - June 11, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Not Available].
Authors: Schaberg T PMID: 27281110 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - June 11, 2016 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

Generation Z: Adolescent Xenobiotic Abuse in the 21st Century.
Authors: Eggleston W, Stork C Abstract NMDA receptor antagonists include the prescription medication ketamine, the illicit xenobiotics PCP, MXE, and other novel PCP analogs, and the OTC medication DXM. The NMDA receptor antagonist most commonly abused by adolescents in the United States is DXM. These xenobiotics cause dissociative effects by non-competitively inhibiting the action of glutamate at the NMDA receptor. Additionally, these agents modulate the actions of monoamine neurotransmitters, agonize opioid receptors, and inhibit nitric oxide synthase. Patients typically present with sympathomimetic and neuropsych...
Source: Adolescent Medicine: State of the Art Reviews - June 11, 2016 Category: Pediatrics Tags: Adolesc Med State Art Rev Source Type: research

Impact of GLI-2012 Spirometric References and Lower Limit of Normal on Prevalence of COPD in Older Urban Thai Persons.
CONCLUSION: Prevalence of COPD in older urban Thai persons was lower when LMS-LLN was substituted for fixed ratio (70%) of FEV1/FVC. Agreement in COPD diagnosis between both criteria was high, but a substantial proportion of subjects may be over-diagnosed PMID: 27276738 [PubMed - in process] (Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet)
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - June 11, 2016 Category: Journals (General) Tags: J Med Assoc Thai Source Type: research

Epidemiology of Antibiotic Use and Antimicrobial Resistance in Selected Communities in Thailand.
CONCLUSION: Antibiotics are widely available and are inappropriately sold and given by grocery stores and retail shops located within local communities in Thailand. Antibiotic-resistant bacteria commonly and freely circulate within the community. Patients with URI and acute diarrhea with no indication for antibiotic therapy can be treated without antibiotics. Findings and observations from this study will be used as part of a social marketing campaign on prevention and containment of AMR to educate people living within communities in Thailand. PMID: 27276737 [PubMed - in process] (Source: Journal of the Medical Associa...
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - June 11, 2016 Category: Journals (General) Tags: J Med Assoc Thai Source Type: research

Food allergy is associated with recurrent respiratory tract infections during childhood.
CONCLUSIONS: Sensitization to β-lactoglobulin increased the risk of rRTI in children under 2 years of age nearly four times. The presence of sensitization to food allergens above 3 years of age did not increase the risk of developing clinical presentation of food allergy other than atopic dermatitis. PMID: 27279819 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - June 11, 2016 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Diagnostic significance of nitric oxide concentrations in exhaled air from the airways in allergic rhinitis patients.
CONCLUSIONS: Exhaled NO should be considered as a marker of airway inflammation. It plays an important role in the differential diagnosis of allergy. PMID: 27279816 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - June 11, 2016 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

PDCD1 PD-1.3 polymorphism and allergic bronchial asthma in Russian and Buryat patients.
CONCLUSIONS: PD-1.3 polymorphism of the PD-1 gene (PDCD1) may contribute to the development of allergic asthma in the Russians but not in the Buryats. Our results could be helpful for a better understanding of the effect of this polymorphism on the development of diseases with strong immune component. PMID: 27286421 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - June 11, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Measuring the Cost of Poor Asthma Control and Exacerbations.
CONCLUSION: Results demonstrate that poor asthma control and exacerbations are strongly associated with higher healthcare expenditures. Results also confirm that collection of validated measures of control such as the ACQ-5 may provide valuable information toward improving clinical and economic outcomes. PMID: 27286240 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - June 11, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Randomized, dose-ranging study of a fluticasone propionate multidose dry powder inhaler in adolescents and adults with uncontrolled asthma not previously treated with inhaled corticosteroids.
CONCLUSIONS: In this study, Fp MDPI 25 and 50 µg provided comparable efficacy and safety to Fp DPI 100 µg, with lower systemic exposure. ClinicalTrials.gov identifier: NCT01479621. PMID: 27285965 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - June 11, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Individual and County Level Predictors of Asthma Related Emergency Department Visits among Children on Medicaid: A Multilevel Approach.
Authors: Baltrus P, Xu J, Immergluck L, Gaglioti A, Adesokan A, Rust G PMID: 27285734 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - June 11, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

A modified breathing exercise program for asthma is easy to perform and effective.
CONCLUSION: A simple program of breathing exercises was found to be effective and could be completed in less than 10 minutes per day. Furthermore, there was a statistically significant improvement in ACT scores post-exercise. PMID: 27285510 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - June 11, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Bronchial provocation testing does not detect exercise-induced laryngeal obstruction.
Conclusion Inspiratory flow parameters obtained during bronchoprovocation tests did not reliably detect EILO. It remains that CLE is an important and key investigation modality in establishing a secure diagnosis of EILO. PMID: 27285291 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - June 11, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Sociodemographic, health related and lifestyle correlates of physical activity in adults with current asthma.
CONCLUSIONS: In adults with current asthma, the main correlates of physical activity are age, total household income, BMI, self-perceived health, anxiety disorder, sedentary time, and fruit and vegetable consumption. These data are important for informing education and exercise interventions for adults with asthma. Future research is needed to determine asthma specific correlates of physical activity. PMID: 27285062 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - June 11, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Does the use of efficacy or effectiveness evidence in cost-effectiveness analysis matter?
CONCLUSIONS: 25 cost-effectiveness studies were included. Ten (40.0%) studies were effectiveness-based, while 15 (60.0%) studies were efficacy-based. Of seventeen studies using endpoints that could be compared to WTP threshold, 7 out of 8 (87.5%) effectiveness-based studies yielded favorable cost-effectiveness results, whereas 4 out of 9 (44.4%) efficacy-based studies yielded favorable cost-effectiveness results. The adjusted odds ratio was 15.12 (95% confidence interval; 0.59 to 388.75) for effectiveness-based versus efficacy-based achieving favorable cost-effectiveness findings. More asthma cost-effectiveness studies use...
Source: Journal of Asthma - June 11, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Asthma quality of life in Saudi Arabia: gender differences.
CONCLUSIONS: Our findings revealed gender-specific differences in the correlates of AQL in Saudi Arabia, particularly in tobacco exposure, socio-economic factors and perceived asthma severity. PMID: 27284849 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - June 11, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Inhaled Corticosteroid Related Adrenal Suppression Detected by Poor Growth and Reversed with Ciclesonide.
CONCLUSIONS: Height velocity should be monitored closely during routine asthma visits to identify potential adrenal suppression associated with inhaled corticosteroids use. Ciclesonide is a good option for asthma treatment that allows for adrenal recovery. PMID: 27284755 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - June 11, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

One-year Mortality in COPD After an Exacerbation: The Effect of Physical Activity Changes During the Event.
In conclusion, PA is the strongest predictor of dying in the following year, i.e., those with worsened PA from baseline to 2 months after an eCOPD or with very low PA levels have a higher risk. PMID: 27285279 [PubMed - as supplied by publisher] (Source: COPD: Journal of Chronic Obstructive Pulmonary Disease)
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - June 11, 2016 Category: Respiratory Medicine Tags: COPD Source Type: research

Characterization and Optimization of Biosynthesis of Bioactive Secondary Metabolites Produced by Streptomyces sp. 8812.
Authors: Rajnisz A, Guśpiel A, Postek M, Ziemska J, Laskowska A, Rabczenko D, Solecka J Abstract The nutritional requirements and environmental conditions for a submerged culture of Streptomyces sp. 8812 were determined. Batch and fed-batch Streptomyces sp. 8812 fermentations were conducted to obtain high activity of secondary metabolites. In the study several factors were examined for their influence on the biosynthesis of the active metabolites-7-hydroxy-6-oxo-2,3,4,6-tetrahydroisoquinoline-3-carboxy acid (C10H9NO4) and N-acetyl-3,4-dihydroxy-L-phenylalanine (C11H13NO5): changes in medium composition, pH of prod...
Source: Polish Journal of Microbiology - June 11, 2016 Category: Microbiology Tags: Pol J Microbiol Source Type: research

Respiratory syncytial virus-associated hospitalizations over three consecutive seasons in children with congenital heart disease
Abstract The purpose of this investigation was to analyze the burden of respiratory syncytial virus (RSV)-related hospitalizations in infants and children with congenital heart disease (CHD) over three consecutive RSV seasons. Retrospectively, all children with hemodynamically significant (HS-CHD) and not significant (HNS-CHD) CHD born between 2004 and 2008 at a tertiary care university hospital and identified by ICD-10 diagnoses were included. Data on RSV-related hospitalizations over the first three years of life covering at least three RSV seasons (November–April) were analyzed. The overall incidence of RSV-...
Source: European Journal of Clinical Microbiology and Infectious Diseases - June 11, 2016 Category: Microbiology Source Type: research

Impact of selective digestive decontamination on respiratory tract Candida among patients with suspected ventilator-associated pneumonia. A meta-analysis
Abstract The purpose here is to establish the incidence of respiratory tract colonization with Candida (RT Candida) among ICU patients receiving mechanical ventilation within studies in the literature. Also of interest is its relationship with candidemia and the relative importance of topical antibiotic (TA) use as within studies of selective digestive decontamination (SDD) versus other candidate risk factors towards it. The incidence of RT Candida was extracted from component (control and intervention) groups decanted from studies of various TA and non-TA ICU infection prevention methods with summary estimates d...
Source: European Journal of Clinical Microbiology and Infectious Diseases - June 11, 2016 Category: Microbiology Source Type: research

Approved Antiviral Drugs over the Past 50 Years.
Abstract Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs categorized into 13 functional groups have been formally approved for the treatment of the following 9 human infectious diseases: (i) HIV infections (protease inhibitors, integrase inhibitors, entry inhibitors, nucleoside reverse transcriptase inhibitors, nonnucleoside reverse transcriptase inhibitors, and acyclic nucleoside phosphonate analogues), (ii) hepatitis B virus (HBV) infections (lamivudine, interferons, nucleoside analogues, and acyclic nucleoside phosphonate analogues), (iii) hepatitis C virus (HCV) infections ...
Source: Clinical Microbiology Reviews - June 11, 2016 Category: Microbiology Authors: De Clercq E, Li G Tags: Clin Microbiol Rev Source Type: research

Vagal Afferent Innervation of the Airways in Health and Disease.
Abstract Vagal sensory neurons constitute the major afferent supply to the airways and lungs. Subsets of afferents are defined by their embryological origin, molecular profile, neurochemistry, functionality, and anatomical organization, and collectively these nerves are essential for the regulation of respiratory physiology and pulmonary defense through local responses and centrally mediated neural pathways. Mechanical and chemical activation of airway afferents depends on a myriad of ionic and receptor-mediated signaling, much of which has yet to be fully explored. Alterations in the sensitivity and neurochemical ...
Source: Physiological Reviews - June 11, 2016 Category: Physiology Authors: Mazzone SB, Undem BJ Tags: Physiol Rev Source Type: research

[Not Available].
Authors: Türp JC, Spranger H Abstract Non-communicable diseases (NCDs), such as cardiovascular diseases, chronic respiratory diseases, cancers, and diabetes mellitus, are responsible for most deaths worldwide. In view of the rising prevalence and the long-term consequences of NCDs, their prevention is a public health priority. Dentistry plays an important role in this endeavor. Since oral and general diseases share common risk factors (e.g., poor oral hygiene, unhealthy diet, alcohol abuse, tobacco consumption, distress), preventive measures may target both oral diseases (e.g., dental caries, periodontal diseases,...
Source: Schweizer Monatsschrift fur Zahnmedizin - June 11, 2016 Category: Dentistry Tags: Swiss Dent J Source Type: research

Anesthetic management of a patient with central airway compression due to posterior mediastinal mass.
We describe anesthetic management of a patient with posterior mediastinal mass compressing the trachea and the left main bronchus presented for left thoracotomy and tumor excision. The patient experienced pain and cough, and exhibited positional dyspnea. Airway was successfully secured with awake nasotracheal intubation and placement of single lumen endobronchial tube. PMID: 27276782 [PubMed - in process] (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - June 11, 2016 Category: Journals (General) Tags: Acta Clin Croat Source Type: research

Simple, timely, safely? laryngeal mask and pediatric airway.
SIMPLE, TIMELY, SAFELY? LARYNGEAL MASK AND PEDIATRIC AIRWAY. Acta Clin Croat. 2016 Mar;55 Suppl 1:55-61 Authors: Karišik M Abstract Laryngeal mask airway (LMA) was a useful, powerful airway management device for routine pediatric airway management, pediatric difficult airway, and in pediatric emergency situations. Over years, various designs, induction and insertion techniques have been described. LMA provides ease of placement and removal as compared with endotracheal intubation, less traumatism for the respiratory tract, better tolerability by patients, improved hemodynamic stability during emergenc...
Source: Acta Clinica Croatica - June 11, 2016 Category: Journals (General) Tags: Acta Clin Croat Source Type: research

Empirical use of antibiotic therapy in the prevention of early onset sepsis in neonates: a pilot study.
CONCLUSIONS: Crystalline penicillin plus gentamicin prescribed within 24 h of life is effective in the prevention of EOS. However, low birth weight neonates have a higher risk of treatment failure. PMID: 27279855 [PubMed] (Source: Archives of Medical Science)
Source: Archives of Medical Science - June 11, 2016 Category: Journals (General) Tags: Arch Med Sci Source Type: research

Outbreak of Burkholderia cepacia complex associated with contaminated liquid soap for hospital use: A case study
This study was conducted to decide the source, to prevent the possible hospital outbreak of BCC and to determine the epidemiological source. Eleven cartridge of liquid ... (Source: African Journal of Microbiology Research)
Source: African Journal of Microbiology Research - June 11, 2016 Category: Microbiology Source Type: research

Characterization and analysis of adverse events in closed liability cases involving anaesthetists who received legal support from the Colombian Society of Anaesthesia and Resuscitation (S.C.A.R.E.), Colombia, 1993–2012
Conclusions In the cases reviewed, the majority of adverse events happened in low risk patients, in low complexity institutions. The PACU was a sensitive setting for the occurrence of adverse events. It is important to consider environmental factors when analysing adverse events. (Source: Colombian Journal of Anesthesiology)
Source: Colombian Journal of Anesthesiology - June 11, 2016 Category: Anesthesiology Source Type: research

Inhibitory effect of 1,2,4-triazole-ciprofloxacin hybrids on Haemophilus parainfluenzae and Haemophilus influenzae biofilm formation in vitro under stationary conditions
Publication date: Available online 10 June 2016 Source:Research in Microbiology Author(s): Urszula Kosikowska, Sylwia Andrzejczuk, Tomasz Plech, Anna Malm Haemophilus parainfluenzae and H. influenzae, upper respiratory tract microbiota representatives, are able to colonize natural and artificial surfaces as biofilm. The aim of the present study was to assay the effect of ten 1,2,4-triazole-ciprofloxacin hybrids on planktonic or biofilm-forming hemophili cells in vitro under stationary conditions on the basis of MICs (minimal inhibitory concentrations) and MBICs (minimal biofilm inhibitory concentrations). In addition...
Source: Research in Microbiology - June 11, 2016 Category: Microbiology Source Type: research

Cortical PGC-1{alpha}-Dependent Transcripts Are Reduced in Postmortem Tissue From Patients With Schizophrenia
The transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1α) has been linked to multiple neurological and psychiatric disorders including schizophrenia, but its involvement in the pathophysiology of these disorders is unclear. Experiments in mice have revealed a set of developmentally-regulated cortical PGC-1α-dependent transcripts involved in calcium buffering (parvalbumin, PV), synchronous neurotransmitter release (synaptotagmin 2, Syt2; complexin 1, Cplx1) and axonal integrity (neurofilamaent heavy chain, Nefh). We measured the mRNA expression of PGC-1α ...
Source: Schizophrenia Bulletin - June 11, 2016 Category: Psychiatry Authors: McMeekin, L. J., Lucas, E. K., Meador-Woodruff, J. H., McCullumsmith, R. E., Hendrickson, R. C., Gamble, K. L., Cowell, R. M. Tags: Regular Article Source Type: research

Evaluation of Biomarkers of Exposure in Smokers Switching to a Carbon-Heated Tobacco Product: A Controlled, Randomized, Open-Label 5-Day Exposure Study
Conclusions: Our results provide clear evidence supporting a reduction in the level of exposure to HPHCs of tobacco smoke in smokers who switch to CHTP under controlled conditions, similar to that observed in SA. Implications: The reductions observed in biomarkers of exposure to HPHCs of tobacco smoke in this short-term study could potentially also reduce the incidence of cancer, cardiovascular and respiratory diseases in those smokers who switch to a heated tobacco product. (Source: Nicotine and Tobacco Research)
Source: Nicotine and Tobacco Research - June 11, 2016 Category: Addiction Authors: Lüdicke, F., Haziza, C., Weitkunat, R., Magnette, J. Tags: Original Investigation Source Type: research