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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 19.

Does inferior vena cava respiratory variability predict fluid responsiveness in spontaneously breathing patients?
Conclusions: In SBP with suspected hypovolemia, vena cava size and respiratory variability do not predict fluid responsiveness. In contrast, a cIVC >42 % may predict an increase in CO after fluid infusion. (Source: Critical Care)
Source: Critical Care - November 13, 2015 Category: Intensive Care Authors: Norair AirapetianJulien MaizelOla AlyamaniYazine MahjoubEmmanuel LorneMelanie LevrardNacim AmmenoucheAziz SeydiFrançois TinturierEric LobjoieHervé DupontMichel Slama Source Type: research

IJERPH, Vol. 12, Pages 14541-14556: Particulate Matter Exposure in a Police Station Located near a Highway
This study evaluated exposure concentrations of particulate matter (PM) in the Sinying police station near a highway located in Tainan, Taiwan, under different traffic volumes, traffic types, and shift times. We focused on periods when the wind blew from the highway toward the police station and when the wind speed was greater than or equal to 0.5 m/s. PM2.5, UFP, and PM-PAHs concentrations in the police station and an upwind reference station were measured. Results indicate that PM2.5, UFP, and PM-PAHs concentrations in the police station can be on average 1.13, 2.17, and 5.81 times more than the upwind reference station ...
Source: International Journal of Environmental Research and Public Health - November 13, 2015 Category: Environmental Health Authors: Yu-Cheng ChenChin-Kai HsuChia WangPerng-Jy TsaiChun-Yuan WangMei-Ru ChenMing-Yeng Lin Tags: Article Source Type: research

Ciliary function and motor protein composition of human fallopian tubes
This study consisted of an observational laboratory study on human FT specimens from five healthy females recruited from April 2012 to December 2013 and a descriptive observational retrospective analysis of a clinical PCD database. PARTICIPANTS/MATERIALS, SETTING, METHODS Human FT tissue was obtained from five healthy females after tubal ligation during caesarean delivery. Motor protein composition was assessed by immunofluorescence microscopy using antibodies against dynein arms and nexin–dynein regulatory complex subunits. Ciliary motility was analysed by high-speed video microscopy. A retrospective search of our ...
Source: Human Reproduction - November 13, 2015 Category: Reproduction Medicine Authors: Raidt, J., Werner, C., Menchen, T., Dougherty, G. W., Olbrich, H., Loges, N. T., Schmitz, R., Pennekamp, P., Omran, H. Tags: Reproductive biology Source Type: research

EMCV 3C Protease Cleaves TANK and Regulates NF-{kappa}B Signaling [Cell Biology]
TRAF family member-associated NF-κB activator (TANK) is a negative regulator of canonical NF-κB signaling in the Toll-like receptor- and B-cell receptor-mediated signaling pathways. However, functions of TANK in viral infection-mediated NF-κB activation remain unclear. Here, we reported that TANK was cleaved by encephalomyocarditis virus 3C at the 197 and 291 glutamine residues, which depends on its cysteine protease activity. In addition, encephalomyocarditis virus 3C impaired the ability of TANK to inhibit TRAF6-mediated NF-κB signaling. Interestingly, we found that several viral proteases encoded by the foot and mou...
Source: Journal of Biological Chemistry - November 13, 2015 Category: Chemistry Authors: Huang, L., Liu, Q., Zhang, L., Zhang, Q., Hu, L., Li, C., Wang, S., Li, J., Zhang, Y., Yu, H., Wang, Y., Zhong, Z., Xiong, T., Xia, X., Wang, X., Yu, L., Deng, G., Cai, X., Cui, S., Weng, C. Tags: Signal Transduction Source Type: research

UV-B exposure reduces locomotor performance by impairing muscle function but not mitochondrial ATP production [RESEARCH ARTICLE]
Ensiyeh Ghanizadeh Kazerouni, Craig E. Franklin, and Frank SeebacherUltraviolet B radiation (UV-B) can reduce swimming performance by increasing reactive oxygen species (ROS) formation. High concentrations of ROS can damage mitochondria resulting in reduced ATP production. ROS can also damage muscle proteins thereby leading to impaired muscle contractile function. We have shown previously that UV-B exposure reduces locomotor performance in mosquitofish (Gambusia holbrooki) without affecting metabolic scope. Our aim was therefore to test whether UV-B influences swimming performance of mosquitofish by ROS-induced damage to m...
Source: Journal of Experimental Biology - November 13, 2015 Category: Biology Authors: Kazerouni, E. G., Franklin, C. E., Seebacher, F. Tags: RESEARCH ARTICLE Source Type: research

Osmoregulation and salinity-induced oxidative stress: is oxidative adaptation determined by gill function? [RESEARCH ARTICLE]
In conclusion, osmoregulating posterior gills are better adapted to dSW exposure than respiratory anterior gills since they are capable of controlling the deleterious effects of the ROS production resulting from this salinity-induced stress. (Source: Journal of Experimental Biology)
Source: Journal of Experimental Biology - November 13, 2015 Category: Biology Authors: Rivera-Ingraham, G. A., Barri, K., Boël, M., Farcy, E., Charles, A.-L., Geny, B., Lignot, J.-H. Tags: RESEARCH ARTICLE Source Type: research

Isolation of Chlamydomonas reinhardtii mutants with altered mitochondrial respiration by chlorophyll fluorescence measurement
Publication date: 10 December 2015 Source:Journal of Biotechnology, Volume 215 Author(s): Simon Massoz, Véronique Larosa, Bastien Horrion, René F. Matagne, Claire Remacle, Pierre Cardol The unicellular green alga Chlamydomonas reinhardtii is a model organism for studying energetic metabolism. Most mitochondrial respiratory-deficient mutants characterized to date have been isolated on the basis of their reduced ability to grow in heterotrophic conditions. Mitochondrial deficiencies are usually partly compensated by adjustment of photosynthetic activity and more particularly by transition to state 2. In this work, ...
Source: Journal of Biotechnology - November 13, 2015 Category: Biotechnology Source Type: research

Anesthetic management of live donor renal transplantation in a recipient with Wegener's granulomatosis
Publication date: Available online 12 November 2015 Source:Indian Journal of Transplantation Author(s): Tanmay Tiwari, Divya Srivastava, Sandeep Sahu, Sanjay Dhiraaj Antineutrophil cytoplasmic autoantibody-associated vasculitis (AAV) is a common cause of rapidly progressive glomerulonephritis resulting in end-stage renal disease (ESRD). Wegener's granulamotosis (WG) is a rare disease of this group that have granulomatosis with polyangiitis, characterized by a triad of necrotizing granulomas in the upper and lower respiratory tracts, small vessel vasculitis, and glomerulonephritis. This case report illustrates the var...
Source: Indian Journal of Transplantation - November 13, 2015 Category: Transplant Surgery Source Type: research

Feline calicivirus and other respiratory pathogens in cats with Feline calicivirus-related symptoms and in clinically healthy cats in Switzerland
Background: Cats with feline calicivirus (FCV)-related symptoms are commonly presented to veterinary practitioners. Various clinical manifestations have been attributed to FCV, i.e. upper respiratory tract disease (URTD), oral ulcerations, gingivostomatitis, limping syndrome and virulent systemic disease. Additionally, healthy cats can shed FCV. The aims of this study were 1) to investigate the frequency of FCV in cats with FCV-related symptoms and in healthy cats in Switzerland, 2) to assess risk and protective factors for infection, such as signalment, housing conditions, vaccination, and co-infection with URTD-associate...
Source: BMC Veterinary Research - November 13, 2015 Category: Veterinary Research Authors: Alice BergerBarbara WilliMarina MeliFelicitas BorettiSonja HartnackAnou DreyfusHans LutzRegina Hofmann-Lehmann Source Type: research

Synergistic pathogenicity in sequential coinfection with Mycoplasma hyorhinisand porcine circovirus type 2
Publication date: Available online 11 November 2015 Source:Veterinary Microbiology Author(s): Dongjie Chen, Yanwu Wei, Liping Huang, Yiping Wang, Jianhui Sun, Wenjuan Du, Hongli Wu, Changming Liu To investigate the synergistic pathogenicity of Mycoplasm hyorhinis(Mhr) with porcine circovirus type 2 (PCV2), thirty 35-day-old piglets were randomly distributed to six groups (n = 5 each): Mhr/PCV2 (group 1, inoculated with Mhr and PCV2 1 week later), PCV2/Mhr (group 2, inoculated with PCV2 and Mhr 1 week later), Mhr–PCV2 (group 3, inoculated with PCV2 and Mhr concurrently), singular PCV2 group (group 4), singular M...
Source: Veterinary Microbiology - November 13, 2015 Category: Veterinary Research Source Type: research

Characterization of immune responses following homologous reinfection of pigs with European subtype 1 and 3 porcine reproductive and respiratory syndrome virus strains that differ in virulence
In conclusion, although there were clear differences in immunological, clinical and virological responses to the primo infection, there were no differences observed in protection against homologous challenge. (Source: Veterinary Microbiology)
Source: Veterinary Microbiology - November 13, 2015 Category: Veterinary Research Source Type: research

Bilateral pallidal and medial temporal lobe ischaemic lesions after opioid overdose
Case presentation A patient with a medical history significant for longstanding lower back pain on chronic narcotics for pain control was admitted to our hospital due to altered content of consciousness after a suicide attempt at home. The patient ingested high doses of oxycodone and contacted emergency services immediately. Patient developed mild altered sensorium and confusion without loss of consciousness, cardiac or respiratory arrest following drug-overdose. Comprehensive laboratory investigations were negative except for the presence of opioids in urine and serum along with trace cannabinoids. No other toxic exposure...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 13, 2015 Category: Neurosurgery Authors: Ramirez-Zamora, A., Ramani, H., Pastena, G. Tags: Genetics, Dementia, Infection (neurology), Neuroimaging, Pain (neurology), Variant Creutzfeld-Jakob Disease, Hospice, Memory disorders (psychiatry), Suicide (psychiatry), Drugs: musculoskeletal and joint diseases Neurological pictures Source Type: research

Effect of cyclophosphamide on fungal infection in SLE mice detected by fluorescent quantitative PCR
Conclusions CTX can alleviate lupus nephritis and the fluorescent quantitative PCR is a rapid and sensitive method for the detection of fungal infection. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 13, 2015 Category: Tropical Medicine Source Type: research

Outcome of Stretta radiofrequency and fundoplication for GERD-related severe asthmatic symptoms
This study aimed to investigate the outcome of treatment with Stretta radiofrequency (SRF) or laparoscopic Nissen fundoplication (LNF). A total of 137 gastroesophageal reflux disease (GERD) patients with severe asthmatic symptoms who responded inadequately to medical treatment for asthma were investigated. The patients were followed up 1 year and 5 years after SRF (n = 82) or LNF (n = 55) treatment. A questionnaire covering 29 related symptoms and medication use was employed. Digestive, respiratory, and ear-nose-throat (ENT) symptom scores significantly decreased after antireflux treatment. Symptom scores respectively chan...
Source: Frontiers of Medicine - November 13, 2015 Category: Journals (General) Source Type: research

Use of lateral flow assays to determine IP-10 and CCL4 levels in pleural effusions and whole blood for TB diagnosis
In this study we analysed samples obtained from patients presenting with symptoms suggestive of TB but prior to confirmation by microbiology in The Gambia. Following clinical and microbiological evaluation they were classified as either having TB or other respiratory disorder (ORD). (Source: Tuberculosis)
Source: Tuberculosis - November 13, 2015 Category: Respiratory Medicine Authors: Jayne S. Sutherland, Joseph Mendy, Awa Gindeh, Gerhard Walzl, Toyin Togun, Olumuyiwa Owolabi, Simon Donkor, Martin O. Ota, Elisa Tjon Kon Fat, Tom HM. Ottenhoff, Annemieke Geluk, Paul LAM. Corstjens Tags: Diagnostics Source Type: research

First insight into the genetic population structure of isolated from pulmonary tuberculosis patients in Egypt
The present study aimed to assess the population structure of Mycobacterium tuberculosis (MTB) isolates from Egypt. A total of 230 MTB isolates were analysed using spoligotyping, large sequence polymorphism (LSPs), mycobacterial interspersed repetitive unit–variable number tandem repeat (MIRU-VNTR) typing and multi-locus sequence typing (MLST). The majority of isolates (93.0%) belonged to lineage 4, including 44.3, 13.4 and 10.8% of the ill-defined T clade, LAM and Haarlem families, respectively, and lineage 3 was identified in 7.0 % of the isolates. (Source: Tuberculosis)
Source: Tuberculosis - November 13, 2015 Category: Respiratory Medicine Authors: Hassan Mahmoud Diab, Chie Nakajima, Saber A. Kotb, Alaa Mokhtar, Nagwa F.M. Khder, Ahmed S.A. Abdelaal, Azza Hegazy, Ajay Poudel, Yogendra Shah, Yasuhiko Suzuki Tags: Epidemiology Source Type: research

Prophylactic antibiotics should be used in children with repaired esophageal atresia/tracheo-esophageal fistula- The Case against
(Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - November 13, 2015 Category: Respiratory Medicine Authors: Adilia Warris Source Type: research

Respiratory symptoms/diseases prevalence is still increasing: a 25-yr population study
few epidemiological surveys on general population samples estimated changes in prevalence of respiratory symptoms/diseases over a long time interval; our study aims to quantify the temporal changes in the prevalence rates of asthma, allergic rhinitis and Chronic Obstructive Pulmonary Disease (COPD) after 25 years from baseline. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - November 13, 2015 Category: Respiratory Medicine Authors: Sara Maio, Sandra Baldacci, Laura Carrozzi, Francesco Pistelli, Mrs. Anna Angino, Marzia Simoni, Giuseppe Sarno, Sonia Cerrai, Franca Martini, Martina Fresta, Patrizia Silvi, Francesco Di Pede, Massimo Guerriero, Giovanni Viegi Source Type: research

Prone position for acute respiratory failure in adults.
CONCLUSIONS: We found no convincing evidence of benefit nor harm from universal application of PP in adults with hypoxaemia mechanically ventilated in intensive care units (ICUs). Three subgroups (early implementation of PP, prolonged adoption of PP and severe hypoxaemia at study entry) suggested that prone positioning may confer a statistically significant mortality advantage. Additional adequately powered studies would be required to confirm or refute these possibilities of subgroup benefit but are unlikely, given results of the most recent study and recommendations derived from several published subgroup analyses. Meta-...
Source: Cochrane Database of Systematic Reviews - November 13, 2015 Category: Journals (General) Authors: Bloomfield R, Noble DW, Sudlow A Tags: Cochrane Database Syst Rev Source Type: research

Rejuvenating Cellular Respiration for Optimizing Respiratory Function- Targeting Mitochondria.
Abstract Altered bioenergetics with increased mitochondrial reactive oxygen species (mtROS) production and degradation of epithelial function are key aspects of pathogenesis in asthma and chronic obstructive pulmonary disease (COPD). This motif is not unique to obstructive airway disease; being reported in related airway diseases such as bronchopulmonary dysplasia (BPD), as well as parenchymal diseases such as pulmonary fibrosis. Similarly, mitochondrial dysfunction in vascular endothelium or skeletal muscles contributes to the development of pulmonary hypertension and systemic manifestations of lung disease. In ex...
Source: Am J Physiol Lung Ce... - November 13, 2015 Category: Respiratory Medicine Authors: Agrawal A, Mabalirajan U Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Carvedilol binding to β2-adrenergic receptors inhibits CFTR-dependent anion secretion in airway epithelial cells.
Abstract Carvedilol functions as a non-selective β-adrenergic receptor/α1-adrenergic receptor antagonist that is used for the treatment of hypertension and heart failure. Previously, carvedilol was shown to function as an inverse agonist, inhibiting G-protein activation while stimulating β-arrestin-dependent signaling and inducing receptor desensitization. In the present study, short circuit current (Isc) measurements using human airway epithelial cells revealed that unlike β-agonists which increase Isc, carvedilol decreased basal and 8-cpt cAMP stimulated current. The decrease in Isc resulted from inhibition o...
Source: Am J Physiol Lung Ce... - November 13, 2015 Category: Respiratory Medicine Authors: Peitzman ER, Zaidman NA, Maniak PJ, O'Grady SM Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

VEGF and Endothelium-Derived Retinoic Acid Regulate Lung Vascular and Alveolar Development.
Abstract Prevention or treatment of lung diseases caused by the failure to form, or destruction of, existing alveoli, as observed in infants with bronchopulmonary dysplasia (BPD) and adults with emphysema, requires understanding of the molecular mechanisms of alveolar development. In addition to its critical role in gas exchange, the pulmonary circulation also contributes to alveolar morphogenesis and maintenance by the production of paracrine factors termed "angiocrines" that impact the development of surrounding tissue. To identify lung angiocrines that contribute to alveolar formation, we disrupted pulmonary vas...
Source: Am J Physiol Lung Ce... - November 13, 2015 Category: Respiratory Medicine Authors: Yun EJ, Lorizio W, Seedorf GJ, Abman SH, Vu TH Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

The p70 Ribosomal S6 Kinase Regulates Subpleural Fibrosis Following Transforming Growth Factor-α Expression in the Lung.
Abstract The p70 ribosomal S6 kinase (S6K) is a downstream substrate that is phosphorylated and activated by the mTOR complex and regulates multiple cellular processes associated with fibrogenesis. Recent studies demonstrate that aberrant mTORC1-S6K signaling contributes to various pathologic conditions, but a direct role in pulmonary fibroproliferation has not been established. Increased phosphorylation of the S6K pathway is detected immediately following transforming growth factor-α (TGFα) expression in a transgenic model of progressive lung fibrosis. To test the hypothesis that the S6K directly regulates pulmo...
Source: Am J Physiol Lung Ce... - November 13, 2015 Category: Respiratory Medicine Authors: Madala SK, Thomas G, Edukulla R, Davidson C, Schmidt S, Schehr A, Hardie WD Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Membrane and Capillary Components of Lung Diffusion in Infants with Bronchopulmonary Dysplasia.
CONCLUSIONS: Our findings are consistent with BPD infants having impaired alveolar development with fewer, but larger alveoli, as well as a reduced pulmonary capillary blood volume. PMID: 26566056 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - November 13, 2015 Category: Respiratory Medicine Authors: Chang DV, Assaf SJ, Tiller CJ, Kisling JA, Tepper RS Tags: Am J Respir Crit Care Med Source Type: research

Use of the sleep clinical record in the follow-up of children with obstructive sleep apnea (OSA) after treatment.
CONCLUSIONS: SCR emerges as a potentially useful instrument for follow-up of children with OSA after treatment. PMID: 26564170 [PubMed - as supplied by publisher] (Source: Sleep and Breathing)
Source: Sleep and Breathing - November 13, 2015 Category: Sleep Medicine Authors: Villa MP, Sujanska A, Vitelli O, Evangelisti M, Rabasco J, Pietropaoli N, Banovcin P, Kheirandish-Gozal L, Gozal D Tags: Sleep Breath Source Type: research

Prevalence and phylogenetic characterization of enterovirus d68 in pediatric patients with acute respiratory tract infection in thailand.
PREVALENCE AND PHYLOGENETIC CHARACTERIZATION OF ENTEROVIRUS D68 IN PEDIATRIC PATIENTS WITH ACUTE RESPIRATORY TRACT INFECTION IN THAILAND. Jpn J Infect Dis. 2015 Nov 13; Authors: Thongpan I, Wanlapakorn N, Vongpunsawad S, Linsuwanon P, Theamboonlers A, Payungporn S, Poovorawan Y Abstract Enterovirus D68 (EV-D68) was associated with severe lower respiratory tract infection and neurological abnormalities including acute myelitis and cranial nerve dysfunction. To determine whether the increased incidence of EV-D68 also occurs in Southeast Asia, we retrospectively tested specimens collected from Thai pediat...
Source: Japanese Journal of Infectious Diseases - November 13, 2015 Category: Infectious Diseases Authors: Thongpan I, Wanlapakorn N, Vongpunsawad S, Linsuwanon P, Theamboonlers A, Payungporn S, Poovorawan Y Tags: Jpn J Infect Dis Source Type: research

Pneumonia in Vietnamese Children Aged 1 to 15 years Due to Atypical Pneumonia Causative Bacteria: Hospital-Based Microbiological and Epidemiological Characteristics.
Abstract Pneumonia caused by Mycoplasma pneumoniae (M), Chlamydophila (Chlamydia) pneumoniae (C) and Legionella pneumophila (L) (these three bacteria are referred as the MCL, hereafter) is not well-documented in Vietnam, which may limit effectiveness of treatment. We investigated epidemiological & microbiological characteristics of MCL-caused pneumonia in hospitalized children aged 1-15 years.Multiplex PCR and specific IgM determination were used to detect the target bacteria. Of 722 community-acquired pneumonia (CAP) children, the MCL were the most frequently found pathogens (215 children, 29.78%). M. pneumoni...
Source: Japanese Journal of Infectious Diseases - November 13, 2015 Category: Infectious Diseases Authors: Huong PL, Hien PT, Lan NT, Binh TQ, Tuan DM, Anh DD Tags: Jpn J Infect Dis Source Type: research

Post-thoracotomy pain relief with subpleural analgesia or thoracic epidural analgesia: randomized clinical trial.
CONCLUSION: Thoracic epidural analgesia is superior to subpleural analgesia for relieving post-thoracotomy pain. We suggest that studies on effective drug dosages for providing subpleural analgesia are necessary. PMID: 26576497 [PubMed - as supplied by publisher] (Source: Sao Paulo Medical Journal)
Source: Sao Paulo Medical Journal - November 13, 2015 Category: Journals (General) Authors: Tezcan AH, Karakurt Ö, Eryazgan MA, Başkan S, Örnek DH, Baldemir R, Koçer B, Baydar M Tags: Sao Paulo Med J Source Type: research

New Outpatient Management Based on a Respiratory Virtual Clinic. An Effective Measure in Times of Austerity.
PMID: 26584718 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - November 13, 2015 Category: Respiratory Medicine Authors: Figueira JM, Hernández Gracia MC, Batista Martín JJ Tags: Arch Bronconeumol Source Type: research

The impact of combined administration of paraquat and maneb on motor and non-motor functions in the rat
Publication date: 17 December 2015 Source:Neuroscience, Volume 311 Author(s): A. Tinakoua, S. Bouabid, E. Faggiani, P. De Deurwaerdère, N. Lakhdar-Ghazal, A. Benazzouz Paraquat (PQ) and maneb (MB) are potential risk factors for Parkinson’s disease. However, their impact on non-motor disorders, monoamine neurotransmission and basal ganglia function is not clearly determined. Here we investigated the effects of combined treatment with PQ/MB on motor behavior, anxiety and “depressive-like” disorders, tissue content of monoamines, and subthalamic nucleus (STN) neuronal activity. Male Sprague–Dawley rats were i...
Source: Neuroscience - November 12, 2015 Category: Neuroscience Source Type: research

Recurrent Respiratory Infections Revealing CD8α Deficiency
We report here the comprehensive immunological evaluation of a child with a CD8A missense mutation, providing evidence that CD8 deficiency increases susceptibility to recurrent respiratory infections without interfering with the TCR-mediated proliferation of T cells. These observations expand the known phenotypes associated with CD8 deficiency. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - November 12, 2015 Category: Allergy & Immunology Source Type: research

The effect of fibreoptic bronchoscopy in acute respiratory distress syndrome: experimental evidence from a lung model
Summary Flexible bronchoscopy is essential for appropriate care during mechanical ventilation, but can significantly affect mechanical ventilation of the lungs, particularly for patients with acute respiratory distress syndrome. We aimed to describe the consequences of bronchoscopy during lung‐protective ventilation in a bench study, and thereby to determine the optimal diameter of the bronchoscope for avoiding disruption of the protective‐ventilation strategy during the procedure. Immediately following the insertion of the bronchoscope into the tracheal tube, either minute ventilation decreased significantly, or posit...
Source: Anaesthesia - November 12, 2015 Category: Anesthesiology Authors: M‐A. Nay, J. Mankikian, A. Auvet, P‐F. Dequin, A. Guillon Tags: Original Article Source Type: research

Type IV Congenital Laryngeal Web: Case Report and 15 Year Follow up
Publication date: Available online 10 November 2015 Source:American Journal of Otolaryngology Author(s): Brendan Sorichetti, John P. Moxham, Frederick K. Kozak A five day old patient with mild VACTERL syndrome had repair of a Type IV congenital laryngeal web with successful decanulation 76days later. Voice and respiratory outcome is good with follow up 15years later. This case presents a rare clinical finding of a type IV laryngeal web successfully repaired with a keel and subsequent long term follow up during an era when it was suggested that repair be delayed until 18months of age at the earliest. (Source: American ...
Source: American Journal of Otolaryngology - November 12, 2015 Category: Endocrinology Source Type: research

Associations between chronic diseases and choking deaths among older adults in the USA: a cross-sectional study using multiple cause mortality data from 2009 to 2013
Conclusions We suggest using overall choking instead of only food-related choking to better describe the associations between chronic diseases and choking. (Source: BMJ Open)
Source: BMJ Open - November 12, 2015 Category: Journals (General) Authors: Wu, W.-S., Sung, K.-C., Cheng, T.-J., Lu, T.-H. Tags: Open access, Epidemiology, Geriatric medicine, Medical management, Public health, Respiratory medicine Research Source Type: research

Effects of low‐dose morphine on perceived sleep quality in patients with refractory breathlessness: A hypothesis generating study
ConclusionFour days of low‐dose morphine improved perceived sleep quality in elderly participants with refractory breathlessness. Regular low‐dose morphine targeted to reduce refractory breathlessness may yield associated benefits by reducing sleep disruption and improving sleep quality. (Source: Respirology)
Source: Respirology - November 12, 2015 Category: Respiratory Medicine Authors: Rodrigo T. Martins, David C. Currow, Amy P. Abernethy, Miriam J. Johnson, Barbara Toson, Danny J. Eckert Tags: Original Article Source Type: research

Changing physical activity and sedentary behaviour in people with COPD
Abstract People with chronic obstructive pulmonary disease (COPD) engage in low levels of physical activity (PA). Given the evidence for the health benefits associated with participating in 150 min of moderate‐to‐vigorous intensity PA each week, there is considerable interest in methods to increase PA in people with COPD. Studies to date have focused largely on exercise training and behavioural approaches, and many have demonstrated minimal, if any effect. An intermediate goal that focuses on reducing time spent in sedentary behaviour (SB) and increasing participation in light intensity PA is a more realistic goal in...
Source: Respirology - November 12, 2015 Category: Respiratory Medicine Authors: Vinicius Cavalheri, Leon Straker, Daniel F. Gucciardi, Paul A. Gardiner, Kylie Hill Tags: Invited Review Series: Unravelling the Many Faces of COPD to Optimize Its Care and Outcomes Source Type: research

Weak association between sleep bruxism and obstructive sleep apnea. A sleep laboratory study
Conclusions The results suggest that (1) sleep arousals in patients with concomitant SB and OSAH are not strongly associated with onset of RMMA/SB and (2) apnea-hypopnea events appear to be related to higher occurrence of other types of sleep oromotor activity, and not SB activity. SB genesis and OSAH activity during sleep are probably influenced by different mechanisms. (Source: Sleep and Breathing)
Source: Sleep and Breathing - November 12, 2015 Category: Respiratory Medicine Source Type: research

Impaired sustained attention and lapses are present in patients with mild obstructive sleep apnea
Conclusions Patients with mild OSA showed increased sustained attention lapses compared with normal subjects. (Source: Sleep and Breathing)
Source: Sleep and Breathing - November 12, 2015 Category: Respiratory Medicine Source Type: research

Time, Dose, and Volume Responses in a Mouse Pulmonary Injury Model Following Ablative Irradiation
Conclusions We determined the time, dose, and volume responses in our established small animal model, and found that lung injury was substantially accelerated and phenotypically different from that of prior studies using non-ablative hemi-thorax and complete thorax irradiation schemes. (Source: Lung)
Source: Lung - November 12, 2015 Category: Respiratory Medicine Source Type: research

Association of multiple genetic variants with chronic obstructive pulmonary disease susceptibility in Hainan region
ConclusionsThis study is the first to provide evidence of importance of rs9296092 and rs950063 for risk of COPD in Hainan Province. Further studies are needed to characterize the functional sequences that cause COPD. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - November 12, 2015 Category: Respiratory Medicine Authors: Yipeng Ding, Huan Niu, Long Zhou, Wenjing Zhou, Jiannan Chen, Shiliang Xie, Tingting Geng, Yanhong Ouyang, Ping He, Pei Sun, Tian Feng, Tianbo Jin Tags: Original Article Source Type: research

Fluid strategies and outcomes in patients with acute respiratory distress syndrome, systemic inflammatory response syndrome and sepsis: a protocol for a systematic review and meta-analysis
Discussion While fluid management has been extensively studied and discussed in the critical care literature, no systematic review has attempted to summarise the evidence for post-resuscitation fluid strategies in critical illness. Results of the proposed systematic review will inform practice and the design of future clinical trials. Systematic review registration PROSPERO CRD42013005608. ( (Source: Systematic Reviews)
Source: Systematic Reviews - November 12, 2015 Category: Global & Universal Source Type: research

Age-specific and sex-specific adult mortality risk in India in 2014: analysis of 0·27 million nationally surveyed deaths and demographic estimates from 597 districts
Publication date: December 2015 Source:The Lancet Global Health, Volume 3, Issue 12 Author(s): Usha Ram, Prabhat Jha, Patrick Gerland, Ryan J Hum, Peter Rodriguez, Wilson Suraweera, Kaushalendra Kumar, Rajesh Kumar, Rajesh Dikshit, Denis Xavier, Rajeev Gupta, Prakash C Gupta, Faujdar Ram Background As child mortality decreases rapidly worldwide, premature adult mortality is becoming an increasingly important contributor to global mortality. Any possible worldwide reduction of premature adult mortality before the age of 70 years will depend on progress in India. Indian districts increasingly have responsibili...
Source: The Lancet Global Health - November 12, 2015 Category: Global & Universal Source Type: research