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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 19.

Single- and multiple-dose pharmacokinetics, pharmacodynamics, and safety of apixaban in healthy Chinese subjects Corrigendum
Cui Y, Song Y, Wang J, Yu Z, Schuster A, Barrett YC, Frost C (Source: International Journal of COPD)
Source: International Journal of COPD - March 27, 2014 Category: Respiratory Medicine Source Type: research

Lung function by impulse oscillometry at age 5–7 years after bronchiolitis at age 0–6 months
ConclusionsThough reduced lung function and increased airway reactivity were rather common, evidence for persistent lung function reduction was rare, less than 1%, at preschool age in children hospitalized for bronchiolitis caused mainly by respiratory syncytial virus at age less than 6 months. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - March 27, 2014 Category: Respiratory Medicine Authors: Eero Lauhkonen, Petri Koponen, Kirsi Nuolivirta, Marita Paassilta, Jyri Toikka, Matti Korppi Tags: Original Article: Respiratory Infections Source Type: research

Early-Stage Development of Novel Cyclodextrin-siRNA Nanocomplexes Allows for Successful Postnebulization Transfection of Bronchial Epithelial Cells
Journal of Aerosol Medicine and Pulmonary Drug Delivery , Vol. 0, No. 0. (Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery)
Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery - March 27, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Protocol for a systematic review and economic evaluation of the clinical and cost-effectiveness of non-hospital-based non-invasive ventilation (NIV) in patients with stable end-stage COPD with hypercapnic respiratory failure
DiscussionThese reviews will attempt to clarify the clinical effectiveness of non-hospital NIV in COPD patients as well as the cost-effectiveness. The findings may indicate whether NIV in a non-hospital setting should be considered more routinely in this patient group, and what the likely cost implications will be.PROSPERO registration: 2012:CRD42012003286. (Source: BioMed Central)
Source: BioMed Central - March 27, 2014 Category: Journals (General) Authors: Chirag DaveAlice TurnerJanine DretzkeSue BaylissDeirdre O¿BrienSue JowettDavid Moore Source Type: research

Mucinous adenocarcinoma arising from supratentorial intramedullary neuroenteric cyst with broncho‐pulmonary differentiation
Neuroenteric cysts are benign intradural endoderm cysts lined by gastrointestinal (GI) or tracheobronchial epithelial cells. Their malignant transformation is extremely rare and only six cases have been reported. In these cases, tissue lineage of the cystic endoderm cells giving rise to carcinoma was not clearly identified either as respiratory or as GI type. Herein, we report a case of mucinous adenocarcinoma arising from the neuroenteric cyst with broncho‐pulmonary differentiation in the right cerebral hemisphere of a Japanese woman in her late 50s. The cyst wall was entirely lined by the following respiratory epitheli...
Source: Neuropathology - March 27, 2014 Category: Neurology Authors: Hidetoshi Okabe, Kanade Katsura, Tsuyoshi Yamano, Hiroshi Tenjin, Yoshikazu Nakahara, Mitsuaki Ishida, Toshikazu Kato Tags: CASE REPORT Source Type: research

Transient paradoxical bronchospasm associated with inhalation of the LAMA AZD9164: analysis of two Phase I, randomised, double-blind, placebo-controlled studies
Conclusions: These results show that transient paradoxical bronchoconstriction can occur in some healthy subjects, in addition to patients with COPD, following inhalation of AZD9164 and that the citrate buffer used in the nebulised formulation cannot have been the only cause of the drop in FEV1 in previous studies. As preclinical data do not provide an explanation, the reasons for this brief post-dose drop in FEV1 remain unclear. However, these results highlight the importance of monitoring lung function immediately post-dose when investigating novel inhaled treatments, even when a rapid onset of effect is not expected.Tri...
Source: BMC Pulmonary Medicine - Latest articles - March 27, 2014 Category: Respiratory Medicine Authors: Carin JorupThomas BengtssonKerstin StrandgårdenUlf Sjöbring Source Type: research

The effect of exposure to chlorine on pulmonary function tests and respiratory and allergic symptoms in Iranian lifeguards
In this study, pulmonary function tests (PFTs) and self-reported respiratory and allergic symptoms in lifeguards were compared with matched control subjects. The frequency of respiratory and allergic symptoms was evaluated in a sample of 38 Iranian male lifeguards and 38 control subjects with similar age, having other jobs from the general population, using a questionnaire including questions on work-related respiratory and allergic symptoms in the past year, smoking habits, and duration of working as a lifeguard. PFTs were also measured in lifeguard subjects before and 15 min after 200 µg inhaled salbutamo...
Source: Toxicology and Industrial Health current issue - March 27, 2014 Category: Toxicology Authors: Boskabady, M., Esmaeilizadeh, M., Boskabady, M. Tags: Articles Source Type: research

High Reliability in Respiratory Rate Assessment in Children with Respiratory Symptomatology in a Rural Area in Mozambique
Early recognition of severe medical conditions is often based on clinical scores and vital sign measurements such as the respiratory rate (RR) count. We designed this study to determine the reliability of RR assessment counted three times during a full minute by independent observers in children in a developing country setting. A total of 55 participants were enrolled in the study. Participant ages ranged from 10 days to 7 years (median 22 months). Agreement for RR count was high (intraclass correlation coefficient of 0.95; 95% confidence interval: 0.93–0.97). Agreement for presence of tachypnea was also high (Kappa ...
Source: Journal of Tropical Pediatrics - March 27, 2014 Category: Tropical Medicine Authors: Lanaspa, M., Valim, C., Acacio, S., Almendinger, K., Ahmad, R., Wiegand, R., Bassat, Q. Tags: Original Papers Source Type: research

Dropouts in sublingual allergen immunotherapy trials – a systematic review
Abstract Participant dropouts can reduce the power of allergen immunotherapy clinical trials. Evaluation of the dropout rate and reasons for dropout are important not only in the planning of clinical studies but are also relevant for adherence to immunotherapy in daily clinical practice. A systematic review was carried out in order to establish the overall dropout rate among published double‐blind, placebo‐controlled randomized clinical trials of sublingual immunotherapy for respiratory allergic diseases. Dropouts were analysed in regards to allergen, formulation, treatment schedule, participant age, study size, number...
Source: Allergy - March 27, 2014 Category: Allergy & Immunology Authors: M. Makatsori, G. W. Scadding, C. Lombardo, G. Bisoffi, E. Ridolo, S. R. Durham, G. Senna Tags: Review Article Source Type: research

A25: The Association of Immunogenetic and Environmental Factors with Disease Course in Patients with Juvenile Idiopathic Inflammatory Myopathies
Conclusion:Immunogenetic factors, including HLA alleles, and environmental factors, including a history of preceding infections and the UV index at diagnosis, were significantly associated with disease course in this population of Caucasian patients with JIIM. Future studies are needed to confirm these associated factors and to identify the value of these factors in determining prognosis. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - March 27, 2014 Category: Rheumatology Authors: G. Esther A. Habers, Adam M. Huber, Gulnara Mamyrova, Terrance P. O'Hanlon, Sharon Adams, Janardan P. Pandey, Frederick W. Miller, Chantal Boonacker, Annet Royen‐Kerkhof, Lisa G. Rider Tags: Poster Presentations Source Type: research

A56: Macrophage Activation Syndrome in Patients With Systemic Juvenile Idiopathic Arthritis Treated With Tocilizumab
Conclusion:The use of TCZ does not appear to be associated with increased risk for MAS in sJIA. There were no unusual clinical or laboratory features in these MAS cases. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - March 27, 2014 Category: Rheumatology Authors: Angelo Ravelli, Rayfel Schneider, Sheila Weitzman, Clare Devlin, Kaori Daimaru, Shumpei Yokota, Syuji Takei, Fabrizio Benedetti Tags: Poster Presentations Source Type: research

A93: Childhood Granulomatosis With Polyangiitis: Standardized Disease Assessment in 6 Czech Children
Conclusion:This small series of patients illustrates a variety of GPA outcomes. A standardized scoring of disease activity and damage enables systematic patient F/U and drives appropriate treatment decision‐making. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - March 27, 2014 Category: Rheumatology Authors: Marek Böhm, Dana Nemcová, Tomáš Dallos, Václav Lád, Terezie Suláková, Eva Jancová, Pavla Dolezalová Tags: Poster Presentations Source Type: research

A132: Farber Disease Explains Subset of Juvenile Idiopathic Arthritis
Conclusion:A high percentage of moderate Farber Disease patients are diagnosed as having Juvenile Idiopathic Arthritis. Several of the patients described were referred to secondary or tertiary centers for treatment, which suggests that this percentage may be understated. Given this finding, it is important to increase the awareness of Farber Disease in the pediatric rheumatology community. Differential diagnosis can be made by accounting for the comparatively early onset of FD, the progressive severity of arthritis in FD, the presence of subcutaneous nodules in the joints, scalp and/or spine of FD patients and an unusual, ...
Source: Arthritis and Rheumatism - March 27, 2014 Category: Rheumatology Authors: Edward Schuchman Tags: Poster Presentations Source Type: research

Respiratory system compliance and resistance in canine anesthesia practice: do we have a reference?
(Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - March 27, 2014 Category: Veterinary Research Authors: João HN Soares Tags: Letter to the Editor Source Type: research

Determination of the Minimum Infusion Rate (MIR) of alfaxalone required to prevent purposeful movement of the extremities in response to a standardised noxious stimulus in goats
Conclusions and Clinical RelevanceAlfaxalone can be used for total intravenous anaesthesia (TIVA) in goats and is associated with minimal adverse effects. Oxygen supplementation is advised, especially when working at higher altitudes. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - March 27, 2014 Category: Veterinary Research Authors: Patience S Ndawana, Brighton T Dzikiti, Gareth Zeiler, Loveness N Dzikiti Tags: Research Paper Source Type: research

The cardiopulmonary effects of a peripheral alpha‐2‐adrenoceptor antagonist, MK‐467, in dogs sedated with a combination of medetomidine and butorphanol
Conclusions and clinical relevanceMK‐467 attenuated the cardiovascular effects of a medetomidine‐butorphanol combination after IV and IM administration. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - March 27, 2014 Category: Veterinary Research Authors: Kati Salla, Flavia Restitutti, Mari Vainionpää, Jouni Junnila, Juhana Honkavaara, Erja Kuusela, Marja Raekallio, Outi Vainio Tags: Research Paper Source Type: research

Does Post‐Infectious Olfactory Loss Affect Mood More Severely Than Chronic Sinusitis With Olfactory Loss?
Conclusions: Post‐URI olfactory loss affected patient mood more severely than chronic sinusitis with a similar degree of olfactory loss. This influence was not affected by sex, age, or TDI score in the post‐URI olfactory loss group. (Source: The Laryngoscope)
Source: The Laryngoscope - March 27, 2014 Category: ENT & OMF Authors: Yong Gi Jung, Jun‐Seok Lee, Gi Cheol Park Tags: Original Report Source Type: research

Readmission to the intensive care unit after cardiac surgery: reasons and outcome.
CONCLUSIONS: The most common cause of patient readmissions to the ICU is cardiovascular instability. Postoperative complications and hospital mortality is significantly higher in readmitted patients. Advanced age, emergency status of operation and longer primary ICU LOS promote readmission to the ICU after cardiac surgery. PMID: 24671911 [PubMed - as supplied by publisher] (Source: Polish Heart Journal)
Source: Polish Heart Journal - March 27, 2014 Category: Cardiology Authors: Jarząbek R, Bugajski P, Greberski K, Błaszczyński J, Słowińska-Jarząbek B, Kalawski R Tags: Kardiol Pol Source Type: research

Cardiopulmonary exercise testing demonstrates maintenance of exercise capacity in hypoxemic patients with pulmonary arteriovenous malformations.
CONCLUSIONS: Hypoxemic patients with pulmonary arteriovenous malformations can maintain normal oxygen delivery/consumption during peak exercise. Following improvement of SaO2 by embolization, patients appeared to reset compensatory mechanisms, and as a result, achieved similar peak oxygen consumption per heart beat, and peak work rates. PMID: 24676541 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - March 27, 2014 Category: Respiratory Medicine Authors: Howard LS, Santhirapala V, Murphy K, Mukherjee B, Busbridge M, Tighe HC, Jackson JE, Hughes JM, Shovlin CL Tags: Chest Source Type: research

Catheter Tract Metastasis Associated with Indwelling Pleural Catheters.
CONCLUSION: IPC-related CTM is uncommon but can complicate both mesothelioma and metastatic carcinomas. The duration of interval after IPC insertion is the key risk factor identified for development of CTM. Symptoms are generally mild and respond well to radiotherapy that can be administered safely without removal of the catheter. PMID: 24676503 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - March 27, 2014 Category: Respiratory Medicine Authors: Thomas R, Budgeon CA, Kuok YJ, Read C, Fysh ET, Bydder S, Lee YC Tags: Chest Source Type: research

The new histological classification of lung primary adenocarcinoma subtypes is a reliable prognostic marker and identifies tumors with different mutation status: the experience of a French cohort.
CONCLUSIONS: IASLC/ATS/ERS classification of lung adenocarcinomas predicts survival in French population. Histological grade correlates with clinical, pathological and molecular parameters suggesting different oncogenic pathways. PMID: 24676429 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - March 27, 2014 Category: Respiratory Medicine Authors: Mansuet-Lupo A, Bobbio A, Blons H, Becht E, Ouakrim H, Didelot A, Charpentier MC, Bain S, Marmey B, Bonjour P, Biton J, Cremer I, Dieu-Nosjean MC, Sautès-Fridman C, Régnard JF, Laurent-Puig P, Alifano M, Damotte D Tags: Chest Source Type: research

Prevalence and associations of venous thromboembolism in patients with newly diagnosed lung cancer.
CONCLUSIONS: The prevalence of VTE was high in patients with newly diagnosed lung cancer. In lung cancer patients, the factors associated with DVT might be different from those associated with PE. An elevated CEA level might facilitate the identification of patients at a higher risk of developing PE. PMID: 24676401 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - March 27, 2014 Category: Respiratory Medicine Authors: Zhang Y, Yang Y, Chen W, Guo L, Liang L, Zhai Z, Wang C, for the China Venous Thromboembolism (VTE) Study Group* Tags: Chest Source Type: research

Current asthma in schoolchildren is related to fungal spores in classrooms.
CONCLUSIONS: Classroom Aspergillus/Penicillium and basidiospores are significantly associated with childhood asthma and ASROH. Government health policy should explore environmental interventions for the elimination of fungal spores in classrooms to reduce the prevalence of childhood asthma. PMID: 24676386 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - March 27, 2014 Category: Respiratory Medicine Authors: Chen CH, Chao HJ, Chan CC, Chen BY, Guo YL Tags: Chest Source Type: research

Mediator effect of depressive symptoms on the association between body mass index and asthma control in adult asthmatics.
CONCLUSIONS: Results indicate that having high depressive symptoms and high BMI are both associated with worse asthma control. However, consistent with our hypotheses, the relationship between BMI and worse asthma control was mediated by depressive symptoms. Future studies should examine the precise role of depressive symptoms in both weight control and asthma control. PMID: 24676351 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - March 27, 2014 Category: Respiratory Medicine Authors: Boudreau M, Bacon SL, Ouellet K, Jacob A, Lavoie KL Tags: Chest Source Type: research

Hymenobacter arcticus sp.nov., isolated from high arctic glacial till.
Abstract A novel red-pink pigmented strain, designated R2-4T, was isolated from a till sample near Ny-Alesund, Svalbard Archipelago, Norway. The cells were aerobic, Gram -negative and rod-shaped. Growth occurred at 4-30 (optimum, 20-22), at pH 6.0-9.0(optimum, pH 7.0) and with 0-1% Nacl added to R2A agar. Phylogenetic analysis based on 16S rRNA gene sequence indicated that strain R2-4T belonged to the genus Hymenobacter. The 16S rRNA gene sequence similarity between strain R2-4T and type strains of related species ranged from 94.51 to 96.05%. Strain R2-4T contained iso-C15:0 and anteiso-C15:0 fatty acids, summed fe...
Source: International Journal of Systematic and Evolutionary Microbiology - March 27, 2014 Category: Microbiology Authors: Chang X, Zheng J, Jiang F, Liu P, Kan W, Qu Z, Fang C, Peng F Tags: Int J Syst Evol Microbiol Source Type: research

SOD3 Dysregulation in a Murine Model of Neonatal Lung Injury.
Abstract Bronchopulmonary dysplasia (BPD), a common chronic respiratory disease following premature birth, is believed to be secondary to oxidative damage from hyperoxia and inflammation that leads to impaired alveolar formation and chronic lung dysfunction. We hypothesized that extracellular superoxide dismutase (SOD3), an antioxidant uniquely targeted to the extracellular matrix (ECM) and alveolar fluid, might have a different response (downregulation) to hyperoxic (O2) injury and recovery in room air (RA), thereby contributing to the persistent airspace injury and inflammation. We used a murine BPD model utilizi...
Source: American Journal of Respiratory Cell and Molecular Biology - March 27, 2014 Category: Molecular Biology Authors: Poonyagariyagorn H, Metzger S, Dikeman D, Lopez Mercado A, Malinina A, Calvi C, McGrath-Morrow S, Neptune E Tags: Am J Respir Cell Mol Biol Source Type: research

Role of Sleep Apnea and CPAP therapy in the incidence of stroke or coronary heart disease in women.
Conclusion. In women, untreated OSA is associated with increased incidence of serious cardiovascular outcomes, particularly incident stroke. Adequate CPAP treatment seems to reduce this risk. PMID: 24673616 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 27, 2014 Category: Respiratory Medicine Authors: Campos-Rodriguez F, Martinez-Garcia MA, Reyes-Nuñez N, Caballero-Martinez I, Catalan-Serra P, Almeida-Gonzalez CV Tags: Am J Respir Crit Care Med Source Type: research

Anthracosis in a Coptic mummy.
PMID: 24684766 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - March 27, 2014 Category: Respiratory Medicine Authors: Isidro A, Malgosa A, Prats-Muñoz G Tags: Arch Bronconeumol Source Type: research

An uncommon intrafissural mass: Pleural primitive neuroectodermal tumor.
PMID: 24684765 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - March 27, 2014 Category: Respiratory Medicine Authors: Hochhegger B, Felicetti JC, Marchiori E Tags: Arch Bronconeumol Source Type: research

The Electronic Cigarette. Official Statement of the Spanish Society of Pneumology and Thoracic Surgery (SEPAR) on the Efficacy, Safety and Regulation of Electronic Cigarettes.
This report sets down the Position Statement of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) on the efficacy and safety of e-cigarettes. This statement declares that e-cigarettes should be regulated as medicinal products. PMID: 24684764 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - March 27, 2014 Category: Respiratory Medicine Authors: Jimenez Ruiz CA, Solano Reina S, de Granda Orive JI, Signes-Costa Minaya J, de Higes Martinez E, Riesco Miranda JA, Altet Gómez N, Lorza Blasco JJ, Barrueco Ferrero M, de Lucas Ramos P Tags: Arch Bronconeumol Source Type: research

The allergic emergency – management of severe allergic reactions
Summary Anaphylaxis is characterized by the sudden onset of acute allergic symptoms involving two or more organ systems. An acute allergic emergency is a challenge for physicians due to its life‐threatening potential. The incidence of anaphylactic reactions has increased in recent years. Most frequent elicitors of mast cell and primarily histamine dependent anaphylactic reactions are food, insect venom or drugs. Allergic ­reactions are graded into four groups according to the classification by Ring and Messmer; grade I is defined by the onset of cutaneous symptoms only whereas grade IV is characterized by cardiovascular...
Source: JDDG - March 27, 2014 Category: Dermatology Authors: Alexandra Werner‐Busse, Torsten Zuberbier, Margitta Worm Tags: CME‐Article Source Type: research

Metal composition of fine particulate air pollution and acute changes in cardiorespiratory physiology.
CONCLUSION: Metals contained in PM2.5 were found to be associated with acute changes in cardiovascular and respiratory physiology. PMID: 24682071 [PubMed - as supplied by publisher] (Source: Environmental Pollution)
Source: Environmental Pollution - March 27, 2014 Category: Environmental Health Authors: Cakmak S, Dales R, Kauri LM, Mahmud M, Van Ryswyk K, Vanos J, Liu L, Kumarathasan P, Thomson E, Vincent R, Weichenthal S Tags: Environ Pollut Source Type: research

A novel integrated strategy for detection of human Bocavirus based on an heminested PCR assay combined with boiling lysis method of samples in human specimens.
Abstract Human Bocavirus (HBoV) has been shown to be associated with acute respiratory tract infection in children. The aim of the work was to develop a novel integrated strategy for human bocavirus detection: heminested PCR assay combined with boiling lysis method of samples. The detection limit of the heminested PCR assay was 1.2 copies of a recombinant DNA plasmid, and no cross-reaction with other respiratory viruses or bacteria was observed. By using the integrated strategy, a total of 202 secretions of the lower respiratory tract of children with acute respiratory diseases were collected and tested. The sample...
Source: Journal of Virological Methods - March 27, 2014 Category: Virology Authors: Chen L, Yao Q, Ma J, Li J, Zhang Q, Yang Y, Li F, Sun Y Tags: J Virol Methods Source Type: research

Respiratory muscle endurance is limited by lower ventilatory efficiency in post-myocardial infarction patients
Conclusions : Post-myocardial infarction patients present lower ventilatory efficiency during respiratory muscle endurance tests, which appears to explain their inferior performance in these tests even in the presence of lower pressure overload and lower metabolic equivalent. (Source: Revista Brasileira de Fisioterapia)
Source: Revista Brasileira de Fisioterapia - March 26, 2014 Category: Physiotherapy Source Type: research

Functional outcomes in patients with chronic obstructive pulmonary disease: a multivariate analysis
Conclusions: The results indicate that the outcomes, while based on functioning parameters in COPD patients, could be partly explained by the personal and clinical factors analyzed, especially by the symptoms assessed by the SGRQ. Thus, it appears that the health conditions of these patients cannot be described by isolated variables, including pulmonary function parameters. (Source: Revista Brasileira de Fisioterapia)
Source: Revista Brasileira de Fisioterapia - March 26, 2014 Category: Physiotherapy Source Type: research

Lung function and six-minute walk test performance in individuals with sickle cell disease
Conclusions : SCD promoted changes in lung function and functional capacity, including RVPs and a reduction in the distance walked in the 6MWT when compared to the predictions. In addition, significant correlations between the variables were observed. Contextualização: A doença falciforme (DF) caracteriza-se por mutação genética na cadeia Beta da hemoglobina, gerando disfunções no organismo, como comprometimento da função pulmonar e da capacidade funcional. Objetivo : Avaliar as alterações da função pulmonar e da capacidade funcional de indivíduos com DF assim como identificar a relação entre essas variá...
Source: Revista Brasileira de Fisioterapia - March 26, 2014 Category: Physiotherapy Source Type: research

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We present the case of an 18-month-old female patient with PB following pneumonia. At 6 months of age, the patient underwent the Glenn procedure due to functionally univentricular heart. Fiberoptic bronchoscopy revealed complete blockage of the left bronchus by mucoid casts. Pharmacotherapy consisted of glucocorticosteroids, azithromycin, and enalapril maleate. The child also received nebulized 3% NaCl solution, which proved to be beneficial. In children submitted to Fontan-type procedures, physicians must be alert for PB, which can be triggered by respiratory tract infection.A bronquite plástica (BP), embora uma causa ra...
Source: Jornal Brasileiro de Pneumologia - March 26, 2014 Category: Respiratory Medicine Source Type: research

Determinants of 1‐year changes in disease‐specific health status in patients with advanced chronic obstructive pulmonary disease: A 1‐year observational study
We aimed to identify baseline and longitudinal determinants of change in disease‐specific health status in patients with advanced chronic obstructive pulmonary disease (COPD). Demographic and clinical characteristics as well as disease‐specific health status (St George's Respiratory Questionnaire, SGRQ) were assessed in 105 outpatients with advanced COPD at baseline and at 4, 8 and 12 months. Eighty‐five patients (81.0%) had complete SGRQ data at baseline and 12 months and were included in analyses. Stepwise multiple regression analysis revealed that lower SGRQ total score, higher depression scores and longer time ne...
Source: International Journal of Nursing Practice - March 26, 2014 Category: Nursing Authors: Sarah Wilke, Martijn A Spruit, Emiel FM Wouters, Jos MGA Schols, Frits ME Franssen, Daisy JA Janssen Tags: Research Paper Source Type: research

Minimally invasive lateral lumbar interbody fusion with direct psoas visualization
Conclusions: Preliminary evidence suggests that minimally invasive lateral interbody fusion with direct psoas visualization may reduce the risk for severe procedural complications. (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - March 26, 2014 Category: Orthopaedics Authors: Philip YuanKasra RowshanRohit VermaLarry MillerJon Block Source Type: research

Impact of multimorbidity: acute morbidity, area of residency and use of health services across the life span in a region of south Europe
Conclusions: Multimorbidity is related to greater use of health care services and higher incidence of acute diseases, increasing the burden on primary care services. The differences related to sex and life-stage observed for multimorbidity and acute diseases suggest that further research on multimorbidity should be stratified according to these factors. (Source: BMC Family Practice)
Source: BMC Family Practice - March 26, 2014 Category: Primary Care Authors: Quintí Foguet-BoreuConcepció ViolanAlbert Roso-LlorachTeresa Rodríguez-BlancoMariona Pons-ViguésMiguel Muñoz-PérezEnriqueta Pujol-RiberaJose Valderas Source Type: research

Inflammatory activity at school age in very low birth weight bronchopulmonary dysplasia survivors
ConclusionsThe inflammatory activity seems to decrease by school age in VLBW BPD survivors. Chorioamnionitis and postnatal corticosteroid treatment may modulate the inflammatory responsiveness in VLBW subjects even up to school age. The respiratory outcome in VLBW infants might be improved by preventing excessive weight gain. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - March 26, 2014 Category: Respiratory Medicine Authors: Päivi H. Korhonen, Piia H. Suursalmi, Tarja Kopeli, Riina Nieminen, Lauri Lehtimäki, Tiina Luukkaala, Matti Korppi, Antti Saari, Eeva Moilanen, Outi K.T. Tammela Tags: Original Article: Neonatal Lung Disease Source Type: research

An atypical presentation of pulmonary air‐leak syndrome and multisystem toxic epidermal necrolysis
We report a child who survived TEN with multisystem involvement including the rare but life threatening occurrence of a pulmonary air‐leak syndrome while also reviewing controversies surrounding TEN's pathophysiology, sequelae, and multidisciplinary approach to management. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - March 26, 2014 Category: Respiratory Medicine Authors: Joseph T. Ellenburg, David Josey Tags: Case Report Source Type: research

Enhancing adherence to inhaled therapies in cystic fibrosis
Nonadherence to inhaled therapies is a major problem in the treatment of cystic fibrosis that can influence lung function and health outcomes. Potential contributors to nonadherence have been identified, including demographic and psychosocial factors, time and convenience of inhaled therapy, and treatment beliefs. Additional research is clearly needed to clarify the contributors and to determine which interventions and technological advances will enhance adherence to inhaled therapies in patients with cystic fibrosis. Nurses and allied health professionals are ideally positioned to assist patients and families with adheren...
Source: Therapeutic Advances in Respiratory Disease - March 26, 2014 Category: Respiratory Medicine Authors: Lomas, P. Tags: Reviews Source Type: research

Tracheobronchial amyloidosis managed with multimodality therapies
We present two cases of tracheobronchial amyloidosis successfully treated with surgery and radiation. (Source: Therapeutic Advances in Respiratory Disease)
Source: Therapeutic Advances in Respiratory Disease - March 26, 2014 Category: Respiratory Medicine Authors: Sommer, P., Kumar, G., Lipchik, R. J., Patel, J. J. Tags: Reviews Source Type: research