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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 2.

Non-cystic fibrosis bronchiectasis: an evidence-base for new therapies
Publication date: Available online 19 November 2014 Source:The Lancet Respiratory Medicine Author(s): Diana Bilton , Michael R Loebinger , Robert Wilson (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - November 20, 2014 Category: Respiratory Medicine Source Type: research

The challenges of trials of antibiotics for pneumonia in low–income countries
Publication date: Available online 19 November 2014 Source:The Lancet Respiratory Medicine Author(s): Kim Mulholland , John B Carlin , Trevor Duke , Martin Weber (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - November 20, 2014 Category: Respiratory Medicine Source Type: research

Asthma 2014: from monoclonals to the microbiome
Publication date: Available online 19 November 2014 Source:The Lancet Respiratory Medicine Author(s): Peter G Gibson , Paul S Foster (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - November 20, 2014 Category: Respiratory Medicine Source Type: research

Remarkable progress toward new treatments for cystic fibrosis
Publication date: Available online 19 November 2014 Source:The Lancet Respiratory Medicine Author(s): Laurie C Eldredge , Bonnie W Ramsey (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - November 20, 2014 Category: Respiratory Medicine Source Type: research

Obstructive sleep apnoea: does one treatment not fit all?
Publication date: Available online 19 November 2014 Source:The Lancet Respiratory Medicine Author(s): Keith K H Wong , Brendon J Yee , Ronald R Grunstein (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - November 20, 2014 Category: Respiratory Medicine Source Type: research

ARDS: promising insights for a challenging syndrome
Publication date: Available online 19 November 2014 Source:The Lancet Respiratory Medicine Author(s): Gordon D Rubenfeld (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - November 20, 2014 Category: Respiratory Medicine Source Type: research

Diurnal Temperature Range Related to Respiratory Tract Infection in Childhood
No abstract available (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - November 19, 2014 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Diagnosis and Management of Recurrent Respiratory Papillomatosis
No abstract available (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - November 19, 2014 Category: Infectious Diseases Tags: ESPID Reports and Reviews Source Type: research

Respiratory Rate Monitoring: Characterizing Performance for Emerging Technologies.
PMID: 25405685 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 19, 2014 Category: Anesthesiology Authors: Kelley SD, Ramsay MA Tags: Anesth Analg Source Type: research

Excessive Variations in the Plethysmographic Waveform During Spontaneous Ventilation: An Important Sign of Upper Airway Obstruction.
Abstract The respiratory variations in the plethysmographic (PLET) waveform of the pulse oximeter during mechanical ventilation can be automatically quantified as the PLET variation index (PVI). Like other dynamic variables, the PVI may provide useful information about fluid responsiveness but only when the patient is receiving fully controlled mechanical ventilation with no spontaneous breathing activity. However, a growing number of monitors that automatically measure and display the values of the PVI and other dynamic variables are being introduced into clinical practice. Using these monitors in spontaneously br...
Source: Anesthesia and Analgesia - November 19, 2014 Category: Anesthesiology Authors: Perel A Tags: Anesth Analg Source Type: research

Inflammatory Bowel Disease Cause-specific Mortality: A Primer for Clinicians
Conclusions:Clinicians should be aware that conventional causes of death such as malignancy do not seem to be as significant a burden as originally perceived. However, emerging threats such as infection including C. difficile are noteworthy. Although CD and UC share similar causes of death, there seems to be some differences in cause-specific mortality. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - November 19, 2014 Category: Gastroenterology Tags: Clinical Review Articles Source Type: research

The diabetic lung--a new target organ?
Authors: Pitocco D, Fuso L, Conte EG, Zaccardi F, Condoluci C, Scavone G, Incalzi RA, Ghirlanda G Abstract Several abnormalities of the respiratory function have been reported in patients with type 1 and type 2 diabetes. These abnormalities concern lung volume, pulmonary diffusing capacity, control of ventilation, bronchomotor tone, and neuroadrenergic bronchial innervation. Many hypotheses have emerged, and characteristic histological changes have been described in the "diabetic lung", which could explain this abnormal respiratory function. Given the specific abnormalities in diabetic patients, the lung could thus...
Source: Review of Diabetic Studies - November 19, 2014 Category: Endocrinology Tags: Rev Diabet Stud Source Type: research

Anesthesia and Increased Hypercarbic Drive Impair the Coordination between Breathing and Swallowing
Conclusions: Anesthesia impaired the coordination between swallowing and respiration. Mild hypercapnia increased the frequency of swallowing during anesthesia and the likelihood of pathological swallowing. During anesthesia, the risk for aspiration may be further increased when ventilatory drive is stimulated. (Source: Anesthesiology)
Source: Anesthesiology - November 19, 2014 Category: Anesthesiology Tags: Perioperative Medicine: Clinical Science Source Type: research

Comparisons of CVID and IgGSD: referring physicians, autoimmune conditions, pneumovax reactivity, immunoglobulin levels, blood lymphocyte subsets, and HLA-A and -B typing in 432 adult index patients.
Authors: Barton JC, Bertoli LF, Barton JC Abstract Common variable immunodeficiency (CVID) and immunoglobulin (Ig) G subclass deficiency (IgGSD) are heterogeneous disorders characterized by respiratory tract infections, selective Ig isotype deficiencies, and impaired antibody responses to polysaccharide antigens. Using univariable analyses, we compared observations in 34 CVID and 398 IgGSD adult index patients (81.9% women) referred to a hematology/oncology practice. Similarities included specialties of referring physicians, mean ages, proportions of women, reactivity to Pneumovax, median serum IgG3 and IgG4 levels...
Source: Journal of Immunology Research - November 19, 2014 Category: Allergy & Immunology Tags: J Immunol Res Source Type: research

Simultaneous detection and differentiation of highly virulent and classical Chinese-type isolation of PRRSV by real-time RT-PCR.
Authors: Xiao S, Chen Y, Wang L, Gao J, Mo D, He Z, Liu X Abstract Porcine reproductive and respiratory syndrome (PRRS) is a leading disease in pig industry worldwide and can result in serious economic losses each year. The PRRS epidemic situation in China has been very complicated since the unprecedented large-scale highly pathogenic PRRS (HP-PRRS) outbreaks in 2006. And now the HP-PRRS virus (HP-PRRSV) and classical North American type PRRSV strains have coexisted in China. Rapid differential detection of the two strains of PRRSV is very important for effective PRRS control. The real-time RT-PCR for simultaneous ...
Source: Journal of Immunology Research - November 19, 2014 Category: Allergy & Immunology Tags: J Immunol Res Source Type: research

Significance of persistent inflammation in respiratory disorders induced by nanoparticles.
Authors: Morimoto Y, Izumi H, Kuroda E Abstract Pulmonary inflammation, especially persistent inflammation, has been found to play a key role in respiratory disorders induced by nanoparticles in animal models. In inhalation studies and instillation studies of nanomaterials, persistent inflammation is composed of neutrophils and alveolar macrophages, and its pathogenesis is related to chemokines such as the cytokine-induced neutrophil chemoattractant (CINC) family and macrophage inflammatory protein-1α and oxidant stress-related genes such as heme oxygenase-1 (HO-1). DNA damages occur chemically or physically by na...
Source: Journal of Immunology Research - November 19, 2014 Category: Allergy & Immunology Tags: J Immunol Res Source Type: research

Respiratory syncytial virus infections in infants affected by primary immunodeficiency.
Authors: Lanari M, Vandini S, Capretti MG, Lazzarotto T, Faldella G Abstract Primary immunodeficiencies are rare inherited disorders that may lead to frequent and often severe acute respiratory infections. Respiratory syncytial virus (RSV) is one of the most frequent pathogens during early infancy and the infection is more severe in immunocompromised infants than in healthy infants, as a result of impaired T- and B-cell immune response unable to efficaciously neutralize viral replication, with subsequent increased viral shedding and potentially lethal lower respiratory tract infection. Several authors have reported...
Source: Journal of Immunology Research - November 19, 2014 Category: Allergy & Immunology Tags: J Immunol Res Source Type: research

Attenuation and immunogenicity of a live high pathogenic PRRSV vaccine candidate with a 32-amino acid deletion in the nsp2 protein.
Authors: Lu W, Sun B, Mo J, Zeng X, Zhang G, Wang L, Zhou Q, Zhu L, Li Z, Xie Q, Bi Y, Ma J Abstract A porcine reproductive and respiratory syndrome virus (PRRSV) QY1 was serially passed on Marc-145 cells. Virulence of different intermediate derivatives of QY1 (P5, P60, P80, and P100) were determined. The study found that QY1 had been gradually attenuated during the in vitro process. Pathogenicity study showed that pigs inoculated with QY1 P100 and P80 did not develop any significant PRRS clinic symptoms. However, mild-to-moderate clinical signs and acute HP-PRRSV symptoms of infection were observed in pigs inocula...
Source: Journal of Immunology Research - November 19, 2014 Category: Allergy & Immunology Tags: J Immunol Res Source Type: research

"Nomophobia": impact of cell phone use interfering with symptoms and emotions of individuals with panic disorder compared with a control group.
CONCLUSIONS: Both groups exhibited dependence on and were comforted by having an MP; however, people with PD and agoraphobia showed significantly more emotional alterations as well as intense physical and psychological symptoms when they were apart from or unable to use an MP compared to healthy volunteers. PMID: 24669231 [PubMed] (Source: Clinical Practice and Epidemiology in Mental Health)
Source: Clinical Practice and Epidemiology in Mental Health - November 19, 2014 Category: Psychiatry Tags: Clin Pract Epidemiol Ment Health Source Type: research

Case Report of a Fatal Intoxication by Nucynta
AbstractTapentadol (Nucynta) is a centrally acting opioid analgesic prescribed for the treatment of moderate to severe acute pain. Its efficacy is believed to be due to μ-opioid receptor agonist activity and inhibition of norepinephrine reuptake resulting in increased norepinephrine concentrations. There is only one other case in the literature relating to the toxicity of this agent or report of a fatality. This case report documents a case in which tapentadol was identified as the cause of death. The tapentadol concentration found in the heart blood submitted in this case was more than 20 times the upper limit of the the...
Source: The American Journal of Forensic Medicine and Pathology - November 19, 2014 Category: Forensic Medicine Tags: Case Reports Source Type: research

Imaging analysis of human metapneumovirus-infected cells provides evidence for the involvement of F-actin and the raft-lipid microdomains in virus morphogenesis
Conclusions: These data suggest that HMPV matures as filamentous particles and that virus morphogenesis occurs within lipid-raft microdomains containing localized concentrations of F-actin. The similarity between HMPV morphogenesis and the closely related human respiratory syncytial virus suggests that involvement of F-actin and lipid-raft microdomains in virus morphogenesis may be a common feature of the Pneumovirinae. (Source: Virology Journal)
Source: Virology Journal - November 19, 2014 Category: Virology Authors: Muhammad JumatTra Nguyen HuongPuisan WongLiat LooBoon TanFiona FenwickGeoffrey TomsRichard Sugrue Source Type: research

Impairment of vascularization of the surface covering epithelium induces ischemia and promotes malignization: a new hypothesis of a possible mechanism of cancer pathogenesis
Conclusion The process of redistribution of vascular network occurring at the interface of epithelial–stromal frontier plays an important role in maintaining the adequate metabolism of cells including those of epithelial covering. Impairment of this mechanism most probably promotes precancerous alterations. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - November 19, 2014 Category: Cancer & Oncology Source Type: research

Using the multi-parameter variability of photoplethysmographic signals to evaluate short-term cardiovascular regulation
This study explores a photoplethysmography (PPG)-based multi-parameter analytical approach using the period, amplitude and baseline of PPG signals to quantitatively assess cardiovascular regulation over a 30 s period. PPG data were recorded from 31 young healthy subjects during conditions of spontaneous respiration, paced respiration with 15 breaths/min and breath holding, with each condition lasting 30 s. The three indices (SD1, SD2, SD1/SD2) in Poincaré plot of the normalized parameters and the correlations between the parameters or the first differences of the parameters were analyzed. The results showed that compare...
Source: Journal of Clinical Monitoring and Computing - November 19, 2014 Category: Information Technology Source Type: research

Morbidity in relation to feeding mode in African HIV-exposed, uninfected infants during the first 6 mo of life: the Kesho Bora study [International nutrition]
Conclusions: Not breastfeeding was associated with increased risk of serious infections especially between 0 and 2.9 mo of age. The randomized controlled trial component of the Kesho Bora study was registered at Current Controlled Trials (www.controlled-trials.com) as ISRCTN71468401. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - November 19, 2014 Category: Nutrition Authors: Bork, K. A., Cournil, A., Read, J. S., Newell, M.-L., Cames, C., Meda, N., Luchters, S., Mbatia, G., Naidu, K., Gaillard, P., de Vincenzi, I. Tags: International nutrition Source Type: research

Efektywność szczepienia przeciwko pneumokokom a częstość występowania infekcji dróg oddechowych oraz ostrego zapalenia ucha środkowego w populacji zdrowych dzieci w wieku 0–24 miesięcy, w zależności od sposobu ich karmienia
Publication date: November–December 2014 Source:Pediatria Polska, Volume 89, Issue 6 Author(s): Jarosław Rożnowski , Bożena Leks , Anna Rożnowska Pneumococcal vaccination, despite the effort of the medical community aimed at introducing it as obligatory, still remains in the Polish vaccination schedule as recommended, and thus have to be paid by parents. 490 healthy children (47.55% boys, 52.45% girls) were observed for the first two years of life. From those, 86 were vaccinated against pneumococcal infection. The chi-square test and odds ratio (OR) were performed for intergroup comparison of the prevalence of uppe...
Source: Pediatria Polska - November 19, 2014 Category: Pediatrics Source Type: research

Hemoptysis in an asthmatic child in the course of varicella – A case report
We report of a case of an asthmatic immunocompetent boy with hemoptysis in the course of varicella pneumonitis. Complications of chickenpox in children and causes of hemoptysis are further discussed. (Source: Pediatria Polska)
Source: Pediatria Polska - November 19, 2014 Category: Pediatrics Source Type: research

Zatorowość płucna w praktyce pediatrycznej – opis przypadku
Publication date: September–October 2014 Source:Pediatria Polska, Volume 89, Issue 5 Author(s): Agata Misiek , Dagmara Smektała , Joanna Mitkowska , Katarzyna Derwich Venous thromboembolic disease is a rare condition in the pediatric population. In the current paper the case of a 17-year-old patient with pulmonary embolism was presented. The patient was admitted to the hospital with signs and symptoms of respiratory infection. The pneumonia was diagnosed and standard doses of antibiotics were introduced, however, no improvement was observed. Because of lingering increase of D-dimer plasma concentration and constant ch...
Source: Pediatria Polska - November 19, 2014 Category: Pediatrics Source Type: research

Objawy kliniczne hipogammaglobulinemii u niemowląt i małych dzieci – znaczenie diagnostyczne „10 Objawów Ostrzegawczych Pierwotnego Niedoboru Odporności”
Conclusions Awareness of primary immunodeficiency is a task of physicians in ambulatory and hospital health care and concerns both pediatricians as well as other medical specialists. “10 Warning Signs of Primary Immunodeficiency” is a valuable assistance to take measures of diagnosing PIDs in children with infections; however, a diverse manifestation of these disorders indicates the necessity of expanding and updating the recommendations for diagnosing PIDs. (Source: Pediatria Polska)
Source: Pediatria Polska - November 19, 2014 Category: Pediatrics Source Type: research

The impact of concomitant pulmonary infection on immune dysregulation in Pneumocystis jirovecii pneumonia
Conclusions: In summary, concurrent pulmonary infection might enhance immune dysregulation of PJP in non-AIDS immunocompromised patients, but did not affect the outcome as evidenced by morbidity and mortality. Because of limited number of cases studied, further studies with larger populations are needed to verify these issues. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - November 19, 2014 Category: Respiratory Medicine Authors: Chung-Wei ChouFang-Chi LinHan-Chen TsaiShi-Chuan Chang Source Type: research

Correction: Singing classes for chronic obstructive pulmonary disease: a randomized controlled trial
In our 2012 paper on the effect of singing classes for patients with COPD which compared them to participation in a films studies group, we cited the wrong clinical trial number - (ISRCTN17544114). This number in fact relates to a previous study we had undertaken, published in 2010 which also evaluated singing classes in COPD but had compared them to a "usual care" arm.The trial number we should have cited is ISRCTN39714922. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - November 19, 2014 Category: Respiratory Medicine Authors: Victoria LordVictoria HumeJulia KellyPhoene CaveJudith SilverMaya WaldmanChris WhiteCayley SmithRebecca TannerMelissa SanchezWilliam ManMichael PolkeyNicholas Hopkinson Source Type: research

Quantifying the real life risk profile of inhaled corticosteroids in COPD by record linkage analysis
Conclusion: The use of ICS in our cohort was not associated with new onset of diabetes, worsening of existing diabetes or fracture hospitalisation. There was however an association with increased cataracts and pneumonia hospitalisations. (Source: Respiratory Research)
Source: Respiratory Research - November 19, 2014 Category: Respiratory Medicine Authors: Rob FlynnThomas MacDonaldAdrian HapcaIsla MacKenzieStuart Schembri Source Type: research

Mycobacterial envelope lipids fingerprint from direct MALDI-TOF MS analysis of intact bacilli
Mycobacterium tuberculosis (Mtb) lipids including glycolipids and lipoglycans play a crucial role in the modulation of the host immune response by targeting the innate receptors C-type lectins, TLRs and the CD1 proteins of class 1. Glycolipids have been shown to be biomarkers of M. tuberculosis strains and also of opportunistic mycobacteria called non-tuberculous mycobacteria. Most of the structural and functional work of the Mtb lipids has been done using lipids arising from M. tuberculosis cell growth in vitro. (Source: Tuberculosis)
Source: Tuberculosis - November 19, 2014 Category: Respiratory Medicine Authors: Gérald Larrouy-Maumus, Germain Puzo Source Type: research

COPD exacerbations: reducing the burden by predicting the future?
This article is currently available as a free download on ingentaconnect (Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - November 19, 2014 Category: Respiratory Medicine Authors: Leung, Janice M.Sin, Don D. Tags: EDITORIALS Source Type: research

Cancer Incidence and Mortality in a Cohort of US Blood Donors: A 20-Year Study.
This study describes the epidemiology of cancer in a cohort of blood donors up to 20 years after blood donation. Records from donors who participated in the Retroviral Epidemiology Donor Study (REDS, 1991-2002) at Blood Centers of the Pacific (BCP), San Francisco, were linked to the California Cancer Registry (CCR, 1991-2010). Standardized incidence ratios (SIR) were estimated using standard US 2000 population, and survival analysis used to compare all-cause mortality among donors and a random sample of nondonors with cancer from CCR. Of 55,158 eligible allogeneic blood donors followed-up for 863,902 person-years, 4,236 (7...
Source: Journal of Cancer Epidemiology - November 18, 2014 Category: Epidemiology Tags: J Cancer Epidemiol Source Type: research

The Impact of Human Rhinovirus Infection in Pediatric Patients Undergoing Heart Surgery
Abstract Human rhinovirus (HRV), the most common cause of upper respiratory infection in children, can present as bronchiolitis, pneumonia, or asthma exacerbations. The impact of HRV in infants and toddlers with congenital heart disease is poorly defined. A case–control study was performed to compare the clinical course for 19 young children with respiratory symptoms who tested positive for rhinovirus after heart surgery with that of 56 matched control subjects. The control subjects were matched by surgical repair, age, weight, and time of the year. Patients with known HRVs before surgery and control subjects w...
Source: Mammalian Genome - November 18, 2014 Category: Genetics & Stem Cells Source Type: research

The findings of a clinical surveillance bronchoalveolar lavage programme in pre‐school patients with cystic fibrosis
ConclusionsThis study suggests that, in young non‐expectorating children with CF, routine surveillance bronchoscopy allows the detection of significant lower airway pathogens and provides the opportunity for targeted treatment of sub‐clinical infection. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - November 18, 2014 Category: Respiratory Medicine Authors: Barry Linnane, Shashi Vaish, Donna Clarke, Niamh O'Sullivan, Paul McNally Tags: Original Article Source Type: research

The changing epidemiology of asthma in Shanghai, China
Journal of Asthma, Ahead of Print. (Source: Journal of Asthma)
Source: Journal of Asthma - November 18, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Effect of acute intermittent hypoxia treatment on ventilatory load compensation and magnitude estimation of inspiratory resistive loads in an individual with chronic incomplete cervical spinal cord injury.
This study evaluated the effect of ten days of AIH treatment on ventilatory load compensation and respiratory perceptual sensitivity to inspiratory resistive loads (IRL), in an individual with chronic, incomplete cervical SCI. Methods Case report and literature review. Findings We report a case of a 55-year-old female with a C4 chronic, incomplete SCI (American Spinal Injury Association Impairment Scale D). The subject underwent evaluation at four time-points: Baseline, Post Sham, AIH Day 1 and AIH Day 10. Significant improvements in airflow generated in response to applied IRL were found after AIH treatment compared to Ba...
Source: Journal of Spinal Cord Medicine - November 18, 2014 Category: Orthopaedics Tags: J Spinal Cord Med Source Type: research

Medical and infectious complications associated with pyelonephritis among pregnant women at delivery.
CONCLUSIONS: Pyelonephritis at delivery admissions is associated with significant medical and infectious morbidity. PMID: 24194632 [PubMed - indexed for MEDLINE] (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - November 18, 2014 Category: OBGYN Tags: Infect Dis Obstet Gynecol Source Type: research

Status epilepticus in the setting of acute encephalitis.
Authors: Lowenstein DH, Walker M, Waterhouse E Abstract Ms. Q, a 29-year-old woman, began to behave strangely, claiming to see and hear imaginary people. The following day, she was confused and somnolent in the morning. In the late morning, she had a generalized tonic-clonic seizure and was transported to the hospital. Her past medical and developmental histories were unremarkable. She took a daily oral contraceptive and had no drug allergies. She worked as a teacher and had been married for one year. On initial examination, blood pressure was 129/82, pulse 88, respiratory rate 16, temperature 37.5 °C. She was stu...
Source: Epilepsy Currents - November 18, 2014 Category: Neurology Tags: Epilepsy Curr Source Type: research

Serotonin: The Anti-SuddenDeathAmine?
Authors: Richerson GB Abstract Sudden unexpected death in epilepsy (SUDEP) is an exceptionally difficult condition to study in humans. Therefore, translational research in animal models has been very important in defining pathophysiological mechanisms of death and identifying potential treatments. These models are helping define whether the primary mechanism of death is cardiac or respiratory. They have also identified a link to the serotonergic system of the brainstem; this, in turn, led to recognition that SUDEP and sudden infant death syndrome (SIDS) may share a common final pathway in the sequence of events tha...
Source: Epilepsy Currents - November 18, 2014 Category: Neurology Tags: Epilepsy Curr Source Type: research

Influenza A/H1N1 Severe Pneumonia: Novel Morphocytological Findings in Bronchoalveolar Lavage.
We present the results of bronchoalveolar lavage (BAL) performed in three patients with severe influenza A/H1N1 pneumonia complicated by acute respiratory distress syndrome (ARDS). Light microscopy analysis of BAL cytocentrifugates showed the presence of characteristic large, mononuclear, plasmoblastic/plasmocytoid-like cells never described before. Via transmission electron microscopy, these cells were classified as atypical type II pneumocytes and some of them showed cytoplasmic vesicles and inclusions. We concluded that plasmoblastic/plasmocytoid-like type II pneumocytes might represent a morphologic marker of A/H1N1 in...
Source: Interdisciplinary Perspectives on Infectious Diseases - November 18, 2014 Category: Infectious Diseases Tags: Interdiscip Perspect Infect Dis Source Type: research