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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 2.

Infectious Triggers of Chronic Lung Allograft Dysfunction
Abstract Survival after lung transplantation is limited in large part due to the high incidence of chronic rejection, known as chronic lung allograft dysfunction (CLAD). Pulmonary infections are a frequent complication in lung transplant recipients, due both to immunosuppressive medications and constant exposure of the lung allograft to the external environment via the airways. Infection is a recognized risk factor for the development of CLAD, and both acute infection and chronic lung allograft colonization with microorganisms increase the risk for CLAD. Acute infection by community acquired respiratory viruses, ...
Source: Current Infectious Disease Reports - May 24, 2016 Category: Infectious Diseases Source Type: research

Novel Strategy To Protect against Influenza Virus-Induced Pneumococcal Disease without Interfering with Commensal Colonization [Microbial Immunity and Vaccines]
Streptococcus pneumoniae commonly inhabits the nasopharynx as a member of the commensal biofilm. Infection with respiratory viruses, such as influenza A virus, induces commensal S. pneumoniae to disseminate beyond the nasopharynx and to elicit severe infections of the middle ears, lungs, and blood that are associated with high rates of morbidity and mortality. Current preventive strategies, including the polysaccharide conjugate vaccines, aim to eliminate asymptomatic carriage with vaccine-type pneumococci. However, this has resulted in serotype replacement with, so far, less fit pneumococcal strains, which has changed the...
Source: Infection and Immunity - May 24, 2016 Category: Infectious Diseases Authors: Greene, C. J., Marks, L. R., Hu, J. C., Reddinger, R., Mandell, L., Roche-Hakansson, H., King-Lyons, N. D., Connell, T. D., Hakansson, A. P. Tags: Microbial Immunity and Vaccines Source Type: research

DAP12 Inhibits Pulmonary Immune Responses to Cryptococcus neoformans [Fungal and Parasitic Infections]
In this study, we demonstrate that DAP12 plays an important inhibitory role in the immune response to C. neoformans. Infectious outcomes in DAP12–/– mice, including survival and lung fungal burden, are significantly improved compared to those in C57BL/6 wild-type (WT) mice. We find that eosinophils and macrophages are decreased while NK cells are increased in the lungs of infected DAP12–/– mice. In contrast to WT NK cells, DAP12–/– NK cells are able to repress C. neoformans growth in vitro. Additionally, DAP12–/– macrophages are more highly activated than WT macrophages, with...
Source: Infection and Immunity - May 24, 2016 Category: Infectious Diseases Authors: Heung, L. J., Hohl, T. M. Tags: Fungal and Parasitic Infections Source Type: research

Obstructive atelectasis of the lung
A 78-year-old man presented with cough, sputum, fever (max 39°C) and neutrophilic leucocytosis (WBC 11.000/mmc). Five months earlier, he had the same symptoms and a CT scan had shown a triangular, wedge-shaped opacity of the middle lobe. No air bronchogram was present (figure 1A). At that time, he was treated with a 10-days course of a cephalosporin, with improvement of symptoms. No further imaging of the lung was obtained. Figure 1(A) CT scan showing a triangular, wedge shaped opacity of the middle lobe witho no air bronchogram, suggestive for obstructive atelectasis. (B) Bronchoscopic view of the obstructed segm...
Source: Postgraduate Medical Journal - May 24, 2016 Category: Journals (General) Authors: Scarlata, S., Rossi Bartoli, I., Pedone, C., Antonelli Incalzi, R. Tags: Journalology, Drugs: infectious diseases, Radiology, Pneumonia (respiratory medicine), Surgical diagnostic tests, Cardiothoracic surgery, General surgery, Radiology (diagnostics), Ethics Images in medicine Source Type: research

Fetal and neonatal outcomes after term and preterm delivery following betamethasone administration in twin pregnancies
Conclusion Betamethasone reduced birth weight, head circumference, and length of female preterm neonates in twin pairs in a dose-dependent manner. The neonatal mortality and morbidity were not improved by betamethasone. (Source: International Journal of Gynecology and Obstetrics)
Source: International Journal of Gynecology and Obstetrics - May 24, 2016 Category: OBGYN Source Type: research

Long-term effects of azithromycin in patients with cystic fibrosis
Low-dose azithromycin has beneficial effects on severity of the lung disease in cystic fibrosis (CF) patients for a period of 6–12 months after initiation of the treatment. Although its impact in the longer term is uncertain, this treatment is frequently used chronically. The aim of this retrospective study was to investigate the effects of low-dose azithromycin treatment on the progression of CF lung disease in patients treated for more than 12 months. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - May 24, 2016 Category: Respiratory Medicine Authors: Clémentine Samson, Aline Tamalet, Hoang Vu Thien, Jessica Taytard, Caroline Perisson, Nadia Nathan, Annick Clement, Pierre-Yves Boelle, Harriet Corvol Source Type: research

Comparison of ventilator-integrated end-tidal CO2 and transcutaneous CO2 monitoring in home-ventilated neuromuscular patients
Non-invasive transcutaneous capnometry (TcCO2) is used to assess the home ventilation's efficiency. Recently, end-tidal CO2 (ETCO2) sensors have been integrated in life-support home ventilators. The purpose of this study was to compare the ventilator-integrated ETCO2 with TcCO2, in home-ventilated neuromuscular disease patients. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - May 24, 2016 Category: Respiratory Medicine Authors: David Orlikowski, Helene Prigent, Xavier Ambrosi, Isabelle Vaugier, Sandra Pottier, Djillali Annane, Frederic Lofaso, Adam Ogna Source Type: research

Behavior change theory, content and delivery of interventions to enhance adherence in chronic respiratory disease: A systematic review
We sought to describe the theory used to design treatment adherence interventions, the content delivered, and the mode of delivery of these interventions in chronic respiratory disease. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - May 24, 2016 Category: Respiratory Medicine Authors: Amanda R. McCullough, Crístín Ryan, Christopher Macindoe, Nathan Yii, Judy M. Bradley, Brenda O'Neill, J. Stuart Elborn, Carmel M. Hughes Source Type: research

Angiopoietin-2 expression in patients with an acute exacerbation of idiopathic interstitial pneumonias
We hypothesized that increased pulmonary vascular permeability may play a role in the pathogenesis of an acute exacerbation of the idiopathic interstitial pneumonias (AE-IIPs). Angiopoietin-2 (Ang-2) promotes endothelial activation, destabilization, and inflammation. The purpose of this study was to examine whether Ang-2 expression was associated with the pathogenesis of AE-IIPs. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - May 24, 2016 Category: Respiratory Medicine Authors: Masaru Ando, Eishi Miyazaki, Tetsutaro Abe, Chihiro Ehara, Akihiro Goto, Taiki Masuda, Suehiro Nishio, Hideaki Fujisaki, Mari Yamasue, Toshihiro Ishii, Yutaka Mukai, Takeo Ito, Shin-ich Nureki, Toshihide Kumamoto, Junichi Kadota Source Type: research

Early pulmonary disease manifestations in cystic fibrosis mice
Altered pulmonary function is present early in the course of cystic fibrosis (CF), independent of documented infections or onset of pulmonary symptoms. New initiatives in clinical care are focusing on detection and characterization of preclinical disease. Thus, animal models are needed which recapitulate the pulmonary phenotype characteristic of early stage CF. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - May 24, 2016 Category: Respiratory Medicine Authors: Rebecca J. Darrah, Anna L. Mitchell, Cara K. Campanaro, Eric S. Barbato, Paul Litman, Abdus Sattar, Craig A. Hodges, Mitchell L. Drumm, Frank J. Jacono Tags: Original Article Source Type: research

Continuous alternating inhaled antibiotics for chronic pseudomonal infection in cystic fibrosis
Inhaled antibiotics are standard of care for treating chronic pseudomonal respiratory infections in cystic fibrosis patients, initially approved for intermittent administration. However, use of continuous inhaled antibiotic regimens of differing combinations is growing. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - May 24, 2016 Category: Respiratory Medicine Authors: Patrick A. Flume, John P. Clancy, George Z. Retsch-Bogart, D. Elizabeth Tullis, Mark Bresnik, P. Alex Derchak, Sandra A. Lewis, Bonnie W. Ramsey Tags: Original Article Source Type: research

Maximal inspiratory pressure is influenced by intensity of the warm-up protocol
In conclusion, a higher intensity inspiratory muscle warm-up protocol (2×12 breaths at 60% of MIP) can increase IM strength. (Source: Respiratory Physiology and Neurobiology)
Source: Respiratory Physiology and Neurobiology - May 24, 2016 Category: Respiratory Medicine Source Type: research

Respirable indium exposures, plasma indium, and respiratory health among indium‐tin oxide (ITO) workers
ConclusionsPlasma indium concentration reflected cumulative respirable indium exposure, which was associated with clinical, functional, and serum biomarkers of lung disease. Am. J. Ind. Med. Published 2016. This article is a U.S. Government work and is in the public domain in the USA. (Source: American Journal of Industrial Medicine)
Source: American Journal of Industrial Medicine - May 24, 2016 Category: Occupational Health Authors: Kristin J. Cummings, M. Abbas Virji, Ji Young Park, Marcia L. Stanton, Nicole T. Edwards, Bruce C. Trapnell, Brenna Carey, Aleksandr B. Stefaniak, Kathleen Kreiss Tags: Research Article Source Type: research

Chronic exposure of tilapia (Oreochromis niloticus) to iron oxide nanoparticles: Effects of particle morphology on accumulation, elimination, hematology and immune responses
Publication date: August 2016 Source:Aquatic Toxicology, Volume 177 Author(s): Mehmet Ates, Veysel Demir, Zikri Arslan, Hasan Kaya, Sevdan Yılmaz, Mustafa Camas Effects of chronic exposure to alpha and gamma iron oxide nanoparticles (α-Fe2O3 and γ-Fe2O3 NPs) were investigated through exposure of tilapia (Oreochromis niloticus) to 0.1, 0.5 and 1.0mg/L (9.2×10−4, 4.6×10−3 and 9.2×10−3 mM) aqueous suspensions for 60days. Fish were then transferred to NP-free freshwater and allowed to eliminate ingested NPs for 30days. The organs, including gills, liver, kidney, intestine, brain, spleen, and muscle tissue o...
Source: Aquatic Toxicology - May 24, 2016 Category: Toxicology Source Type: research

Expression analysis of Shh signaling members in early stages of chick lung development
Abstract Lung organogenesis is guided by epithelial–mesenchymal interactions that coordinate cellular events responsible for the formation of the respiratory system. Several signaling pathways have been implicated in this process; among them, sonic hedgehog (Shh) signaling has emerged as a crucial regulator of branching morphogenesis in the mammalian lung. Canonical Shh signaling requires the presence of patched (Ptch) and smoothened (Smo) transmembrane receptors in order to induce the activation of glioblastoma (Gli) zinc finger transcription factors that are the true effectors of the pathway. Signal transducti...
Source: Histochemistry and Cell Biology - May 24, 2016 Category: Biomedical Science Source Type: research

Pathogenic characteristics of a novel triple-reasserted H1N2 swine influenza virus
Publication date: Available online 24 May 2016 Source:Biologicals Author(s): Huili Liu, Jie Tao, Pengchao Zhang, Xiuchen Yin, Zhuo Ha, Chunling Zhang A novel triple reasserted H1N2 virus A/swine/Shanghai/1/2007 (SH07) was isolated from nasal swabs of weaned pig showing clinical symptoms of coughing and sneezing. To explore the virus characteristics, mice, chickens and pigs were selected for pathogenicity study. Pigs inoculated intranasally with 106 TCID50 SH07 showed clinical symptoms with coughing and sneezing, but no death. The virus nuclear acid was detected in many tissues using real-time PCR, which was mainly ...
Source: Biologicals - May 24, 2016 Category: Biology Source Type: research

Prolonged length of stay after posterior surgery for cervical spondylotic myelopathy in patients over 65years of age
In conclusion, patients over the age of 65 who underwent posterior surgery for cervical myelopathy and stayed over 6days in hospital were defined as having PLOS. Hospital charges and mortality rates were significantly higher for patients who experienced PLOS. Potentially modifiable and/or preventable risk factors were also identified. (Source: Journal of Clinical Neuroscience)
Source: Journal of Clinical Neuroscience - May 24, 2016 Category: Neuroscience Source Type: research

Role of Flow Cytometry in the Diagnosis of Chronic Granulomatous Disease: the Egyptian Experience
Conclusion In countries with limited resources and yet large number of CGD patients, the analysis of the defective proteins by flow cytometry is an optimum solution for confirming the diagnosis and is a step for targeted sequencing in families seeking prenatal diagnosis. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - May 24, 2016 Category: Allergy & Immunology Source Type: research

The Transient Receptor Potential Vanilloid 1 Antagonist Capsazepine Improves the Impaired Lung Mechanics during Endotoxemia
In this study, lung function and a histological analysis were performed to evaluate the impact of transient receptor potential vanilloid‐1 receptor (TRPV1) antagonist (capsazepine; CPZ) on the lipopolysaccharide (LPS)‐induced lung injury in mice. For this, adult mice pre‐treated with CPZ or vehicle received intraperitoneal injections of LPS or saline and 24 hr after, the mice were anaesthetized, and lung mechanics was evaluated. The LPS‐challenged mice exhibited substantial mechanical impairment, characterized by increases in respiratory system resistance, respiratory system elastance, tissue damping and tissue ela...
Source: Basic and Clinical Pharmacology and Toxicology - May 24, 2016 Category: Drugs & Pharmacology Authors: Layla D. M. Cabral, Alexandre Giusti‐Paiva Tags: Original Article Source Type: research

Diaphragmatic excursion measurement in emergency patients with acute dyspnea: toward a new diagnostic tool?
During acute dyspnea (AD), respiratory exhaustion is mainly due to diaphragm fatigue. The primary objective was to validate inter-observer reproducibility of diaphragmatic excursion (DE) in ED patients admitted for AD. The secondary objectives were to assess the feasibility of DE measurement and intra-observer reproducibility. Finally, we examined whether the DE value was associated with a need for non-invasive ventilation (NIV). (Source: The American Journal of Emergency Medicine)
Source: The American Journal of Emergency Medicine - May 24, 2016 Category: Emergency Medicine Authors: Xavier Bobbia, Aude Clément, Pierre Géraud Claret, Sophie Bastide, Sandrine Alonso, Patricia Wagner, Tristan Tison, Laurent Muller, Jean Emmanuel de La Coussaye Source Type: research

Emergent Radiation Therapy as Definite Airway Management for Dyspnea with Mediastinal Mass
A previously healthy 21 year old woman presented with an a large mediastinal mass in respiratory distress, maximally extracting oxygen by arterial venous blood gas differential, but without hypoxia or airway obstruction in the upright posture with supplemental oxygen. CT scan showed near total compression of long sections of her primary bronchi bilaterally. The patient was not intubated secondary to high risk to total airway occlusion. As the CT suggested lymphoma as the most likely etiology of the mass, she was started on steroids and transferred for emergent radiation. (Source: The American Journal of Emergency Medicine)
Source: The American Journal of Emergency Medicine - May 24, 2016 Category: Emergency Medicine Authors: Elizabeth Magassy Dorn, Stephen Morris Source Type: research

Multimodality Peak Ictal Vital Signs during Video-EEG Monitoring
Vital signs (VS) are standard, reliable, and easily accessible emergency care indicators of essential cardiopulmonary function. As such, extreme fluctuation of ictal VS (iVS) can portend morbidity and mortality in patients with epileptic seizures (ES), and may serve to differentiate ES from recurrent psychogenic nonepileptic seizures (PNES), paroxysmal events that are frequently misdiagnosed as epilepsy [1–7]. Seizures affect the autonomic nervous system with measurable effects on cardiac [8] and respiratory [9] function, as well as impacts on blood pressure (BP) [9]. (Source: Seizure: European Journal of Epilepsy)
Source: Seizure: European Journal of Epilepsy - May 24, 2016 Category: Neurology Authors: William O. Tatum, Emily K. Acton, Michael E. Langston, Kirsten Yelvington, Cammi Bowman, Jerry J. Shih, William P. Cheshire Source Type: research

Hospitalizations with Lower Respiratory Tract Infections among American Indian and Alaska Native Children Under Age 5 Years: The Use of Non-Federal Hospital Discharge Data to Analyze Rates
American Indian and Alaska Native (AI/AN) children aged (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - May 24, 2016 Category: Pediatrics Authors: Rosalyn Singleton, Robert C. Holman Tags: Editorial Source Type: research

Statins for the prevention and treatment of acute lung injury and acute respiratory distress syndrome: a systematic review and meta‐analysis
Abstract The purpose of this meta‐analysis was to assess whether statins could reduce the morbidity of acute lung injury and acute respiratory distress syndrome (ALI/ARDS) in high‐risk patients and improve the clinical outcomes of patients with ALI/ARDS. Studies were obtained from PubMed, Medline, Embase and Cochrane Central Register of Controlled Trials. Randomized controlled trials (RCTs) and cohort studies, which reported morbidity, mortality, ventilator‐free days, length of stay in intensive care unit and hospital or oxygenation index, were included in our meta‐analysis. Risk ratio (RR) and weighted mean differ...
Source: Respirology - May 24, 2016 Category: Respiratory Medicine Authors: Bo Xiong, Chunbin Wang, Jie Tan, Yin Cao, Yanke Zou, Yuanqing Yao, Jun Qian, Shunkang Rong, Yuwen Huang, Jing Huang Tags: Systematic Review Source Type: research

Upper airway microbial colonization in patients with neuromuscular disorders
ConclusionSevere respiratory compromise in patients with NMD is associated with upper airway microbial airway colonization, which might contribute to respiratory morbidity/insufficiency. (Source: Respirology)
Source: Respirology - May 24, 2016 Category: Respiratory Medicine Authors: Florian Stehling, Nadine Pieper, Anastasios Bouikidis, Joerg Steinmann, Peter‐Michael Rath, Uwe Mellies Tags: Original Article Source Type: research

Reduced transforming growth factor β1 (TGF‐β1) in the repair of airway epithelial cells of children with asthma
ConclusionOur data has highlighted the importance of TGF‐β1 in pAEC wound repair in vitro. The significantly lower levels seen in asthmatic pAEC subsequently contributes to the dysregulated repair observed in these cells. (Source: Respirology)
Source: Respirology - May 24, 2016 Category: Respiratory Medicine Authors: Kak‐Ming Ling, Erika N. Sutanto, Thomas Iosifidis, Elizabeth Kicic‐Starcevich, Kevin Looi, Luke W. Garratt, Kelly M. Martinovich, Francis J. Lannigan, Darryl A. Knight, Stephen M. Stick, Anthony Kicic Tags: Original Article Source Type: research

Endocan: a novel predictor of endothelial dysfunction in obstructive sleep apnea syndrome
ConclusionSerum endocan level is strongly associated with the severity of OSA and endothelial dysfunction. Endocan might be a useful early novel marker for premature vascular endothelial system damage in OSA patients. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 24, 2016 Category: Respiratory Medicine Authors: Asiye Kanbay, Erkan Ceylan, Handan İnönü Köseoğlu, Mustafa Çalışkan, Mumtaz Takir, Selcan Tulu, Ozge Telci Çaklılı, Osman Köstek, Aybala Erek, Baris Afsar Tags: Original Article Source Type: research

Increased mitochondrial arginine metabolism supports bioenergetics in asthma
High levels of arginine metabolizing enzymes, including inducible nitric oxide synthase (iNOS) and arginase (ARG), are typical in asthmatic airway epithelium; however, little is known about the metabolic effects of enhanced arginine flux in asthma. Here, we demonstrated that increased metabolism sustains arginine availability in asthmatic airway epithelium with consequences for bioenergetics and inflammation. Expression of iNOS, ARG2, arginine synthetic enzymes, and mitochondrial respiratory complexes III and IV was elevated in asthmatic lung samples compared with healthy controls. ARG2 overexpression in a human bronchial ...
Source: Journal of Clinical Investigation - May 23, 2016 Category: Biomedical Science Authors: Weiling Xu, Sudakshina Ghosh, Suzy A.A. Comhair, Kewal Asosingh, Allison J. Janocha, Deloris A. Mavrakis, Carole D. Bennett, Lourdes L. Gruca, Brian B. Graham, Kimberly A. Queisser, Christina C. Kao, Samuel H. Wedes, John M. Petrich, Rubin M. Tuder, Satis Source Type: research

Lung clearance index and moment ratios at different cut‐off values in infant multiple‐breath washout measurements
ConclusionIn infants, the diagnostic performance of MBW strongly depends on the point of analysis. The cut‐off with the highest discriminative power to detect ventilation inhomogeneity in infants with cystic fibrosis and after preterm birth was at 1.5% tracer gas concentration. Pediatr Pulmonol. 2016; 9999:XX–XX. © 2016 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - May 23, 2016 Category: Respiratory Medicine Authors: Barbara Egger, Kerstin Jost, Pinelopi Anagnostopoulou, Sophie Yammine, Florian Singer, Carmen Casaulta, Urs Frey, Philipp Latzin Tags: Original Article Source Type: research

ECLS May Save Mother and Fetus
In pregnant women with acute respiratory distress syndrome, extracorporeal life support can be effective and safe for both the mother and fetus, according to a meta-analysis of 332 articles published... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - May 23, 2016 Category: OBGYN Source Type: research

ECLS May Save Mother and Fetus
In pregnant women with acute respiratory distress syndrome, extracorporeal life support can be effective and safe for both the mother and fetus, according to a meta-analysis of 332 articles published... (Source: Hospitalist News)
Source: Hospitalist News - May 23, 2016 Category: Hospital Management Source Type: research

[A Case of Giant Fibrovascular Polyp of the Esophagus, Treated Successfully by Endoscopic Resection].
Abstract Fibrovascular polyps are rare benign intraluminal tumors that usually arise from the cervical esophagus. These often present as very large sized pedunculated polyps and cause symptoms including dysphagia and respiratory distress. Generally, large polyps are surgically excised, while endoscopic resection is limited to smaller polyps. Herein, we present a giant fibrovascular polyp of the esophagus treated successfully by endoscopic resection. PMID: 27206436 [PubMed - as supplied by publisher] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - May 23, 2016 Category: Gastroenterology Authors: Lee JW, Kim GH, Kim JK, Park CH, Song BG, Shin DH, Ha DW, Am Song G Tags: Korean J Gastroenterol Source Type: research

[Outdoor pollution and its effects on lung health. Expert document from the groupe pathologies pulmonaires professionnelles environnementales et iatrogéniques (PAPPEI) of the Société de pneumologie de langue française (SPLF)].
Authors: Charpin D, Pairon JC, Annesi-Maesano I, Caillaud D, de Blay F, Dixsaut G, Housset B, Meurice JC, Roussel I, Zmirou D, Delaval P, Dalphin JC, groupe pathologies pulmonaires professionnelles environnementales et iatrogéniques (PAPPEI) et le conseil scientifique de la Société de pneumologie de langue française (SPLF) PMID: 27209117 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - May 23, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Impact of physical exercise in cystic fibrosis patients: A systematic review].
CONCLUSIONS: Evidence that physical exercise benefits lung function, exercise capacity and quality of life in cystic fibrosis patient is inconsistent and evidence does not support a particular standardized program for all patients. PMID: 27209116 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - May 23, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

Differential expression of pro-inflammatory and oxidative stress mediators induced by nitrogen dioxide and ozone in primary human bronchial epithelial cells.
CONCLUSION: We have demonstrated that these two oxidant gases stimulate differing mechanistic responses in vitro and these responses occur at dissimilar times. PMID: 27206323 [PubMed - in process] (Source: Inhalation Toxicology)
Source: Inhalation Toxicology - May 23, 2016 Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research

Raised serum levels of IGFBP-1 and IGFBP-2 in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disorder of unknown origin, which ultimately leads to death. Several growth factors such as IGFs (insulin-like-growth factor) and IGFBPs (insulin like grow... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 23, 2016 Category: Respiratory Medicine Authors: J. Guiot, B. Bondue, M. Henket, J. L. Corhay and R. Louis Source Type: research

Comparison of next generation sequencing, SNaPshot assay and real-time polymerase chain reaction for lung adenocarcinoma EGFR mutation assessment
The epidermal growth factor receptor (EGFR) mutation status assessment has become increasingly important given the significant impact of tyrosine kinase inhibitors in lung cancer management. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 23, 2016 Category: Respiratory Medicine Authors: Andrei-Tudor Cernomaz, Ina Iuliana Macovei, Ionut Pavel, Carmen Grigoriu, Mihai Marinca, Florent Baty, Simona Peter, Radu Zonda, Martin Brutsche and Bogdan- Dragos Grigoriu Source Type: research

From “traction bronchiectasis” to honeycombing in idiopathic pulmonary fibrosis: A spectrum of bronchiolar remodeling also in radiology?
The diagnostic and prognostic impact of traction bronchiectasis on high resolution CT scan (HRCT) in patients suspected to have idiopathic pulmonary fibrosis (IPF) is increasing significantly. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 23, 2016 Category: Respiratory Medicine Authors: Sara Piciucchi, Sara Tomassetti, Claudia Ravaglia, Christian Gurioli, Carlo Gurioli, Alessandra Dubini, Angelo Carloni, Marco Chilosi, Thomas V Colby and Venerino Poletti Source Type: research

The MK2/HuR signaling pathway regulates TNF-α-induced ICAM-1 expression by promoting the stabilization of ICAM-1 mRNA
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are characterized by acute lung inflammation. Intercellular adhesion molecule-1 (ICAM-1) and interleukin-8 (IL-8) play an important role i... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 23, 2016 Category: Respiratory Medicine Authors: Ting Wu, Jia-Xin Shi, Shen Geng, Wei Zhou, Yi Shi and Xin Su Source Type: research