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Respiratory Medicine

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 2.

A retrospective comparison of antibiotic regimens for preterm premature rupture of membranes.
CONCLUSION: Among women with preterm premature rupture of membranes between 24 and 34 completed weeks of gestation, substitution of azithromycin for erythromycin in the recommended antibiotic regimen did not affect latency or any other measured maternal or fetal outcomes. LEVEL OF EVIDENCE: : III. PMID: 25162251 [PubMed - in process] (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - August 30, 2014 Category: OBGYN Authors: Pierson RC, Gordon SS, Haas DM Tags: Obstet Gynecol Source Type: research

Maternal Physiologic Parameters in Relationship to Systemic Inflammatory Response Syndrome Criteria: A Systematic Review and Meta-analysis.
CONCLUSION: Current SIRS criteria often overlap with normal physiologic parameters during pregnancy and the immediate postpartum period; thus, alternative criteria must be developed to diagnose maternal sepsis. PMID: 25162253 [PubMed - in process] (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - August 30, 2014 Category: OBGYN Authors: Bauer ME, Bauer ST, Rajala B, MacEachern MP, Polley LS, Childers D, Aronoff DM Tags: Obstet Gynecol Source Type: research

Perinatal outcomes and hospital costs in gastroschisis based on gestational age at delivery.
CONCLUSION: In pregnancies complicated by gastroschisis, and with no other known major indications, birth at early term or later term gestation, when compared with delivery before 37 weeks of gestation, is associated with improved perinatal outcomes and lower medical costs. LEVEL OF EVIDENCE: : II. PMID: 25162254 [PubMed - in process] (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - August 30, 2014 Category: OBGYN Authors: Cain MA, Salemi JL, Paul Tanner J, Mogos MF, Kirby RS, Whiteman VE, Salihu HM Tags: Obstet Gynecol Source Type: research

NewsCAP: Upsurge in Middle East respiratory syndrome (MERS) linked to inadequate infection control.
Authors: PMID: 25166237 [PubMed - in process] (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - August 30, 2014 Category: Nursing Tags: Am J Nurs Source Type: research

Prevalence of malnutrition in patients admitted to a major urban tertiary care hospital in Hanoi, Vietnam.
CONCLUSIONS: The prevalence of malnutrition was high in this cohort of hospitalized patients, particularly in adults, but comparable to other published reports. Obesity was nearly nonexistent in both children and adults. PMID: 25164455 [PubMed - in process] (Source: Asia Pacific Journal of Clinical Nutrition)
Source: Asia Pacific Journal of Clinical Nutrition - August 30, 2014 Category: Nutrition Authors: Huong PT, Lam NT, Thu NN, Quyen TC, Lien DT, Anh NQ, Henry EG, Oliver L, Apovian CM, Ziegler TR, Lenders C Tags: Asia Pac J Clin Nutr Source Type: research

[Review] China's distinctive engagement in global health
China has made rapid progress in four key domains of global health. China's health aid deploys medical teams, constructs facilities, donates drugs and equipment, trains personnel, and supports malaria control mainly in Africa and Asia. Prompted by the severe acute respiratory syndrome (SARS) outbreak in 2003, China has prioritised the control of cross-border transmission of infectious diseases and other health-related risks. In governance, China has joined UN and related international bodies and has begun to contribute to pooled multilateral funds. (Source: LANCET)
Source: LANCET - August 30, 2014 Category: Journals (General) Authors: Peilong Liu, Yan Guo, Xu Qian, Shenglan Tang, Zhihui Li, Lincoln Chen Tags: Review Source Type: research

Mobile-phone-based home exercise training program decreases systemic inflammation in COPD: a pilot study
Conclusions: A mobile-phone-based system can provide an efficient home endurance exercise training program with improved exercise capacity, strength of limb muscles and a decrease in serum CRP and IL-8 in COPD patients. Decreased systemic inflammation may contribute to these clinical benefits. (Clinical trial registration No.: NCT01631019) (Source: BMC Pulmonary Medicine - Latest articles)
Source: BMC Pulmonary Medicine - Latest articles - August 30, 2014 Category: Respiratory Medicine Authors: Chun-Hua WangPai-Chien ChouWen-Ching JoaLi-Fei ChenTe-Fang ShengShu-Chuan HoHorng-Chyuan LinChien-Da HuangFu-Tsai ChungKian ChungHan-Pin Kuo Source Type: research

Three‐dimensional analysis of sexual dimorphism in human thoracic vertebrae: Implications for the respiratory system and spine morphology
ABSTRACT Sexual dimorphism is important for intraspecific variation and well studied in the human skeleton. In the thoracic part of the spine sexual dimorphism is expected for differences in the respiratory system related to body mass, lung capacity, and energetics, and in the reproductive system for adaptations to pregnancy (lower spine lordosis, posture). However, little is known about sexual dimorphism in this anatomical region. We use three‐dimensional (3D)‐geometric morphometrics to test hypotheses on sexual dimorphism in the first 10 thoracic vertebrae (T1–T10). Forty‐six 3D‐landmarks were measured on verte...
Source: American Journal of Physical Anthropology - August 30, 2014 Category: Physiology Authors: Markus Bastir, Antonio Higuero, Luís Ríos, Daniel García Martínez Tags: Research Article Source Type: research

The analysis of respiration-induced pancreatic tumor motion based on reference measurement
Conclusion: Our results support the use of 20-mm margin in the SI direction and 5-mm margins in the LL and AP directions to account for respiratory motion without reference measurement. Single measurement of tumor motion allows only modest margin reduction. Further margin reduction is only possible when there is on-line tumor motion control according to internal markers. (Source: Radiation Oncology)
Source: Radiation Oncology - August 30, 2014 Category: Cancer & Oncology Authors: Lukas KnybelJakub CvekBretislav OtahalTomas JonsztaLukas MolendaDaniel CzernyEva SkacelikovaMarian RybarPavel DvorakDavid Feltl Source Type: research

PRAM Score as Predictor of Pediatric Asthma Hospitalization / La Puntuación del PRAM como Predictor de Ingreso en Pacientes con Asma Pediátrico
ConclusionsThe 3‐hour PRAM scores best predicts the need for hospitalization. These results may be applied in clinical settings to facilitate the decision to admit or initiate more aggressive adjunctive therapy to decrease the need for hospitalization. Resumen ObjetivosDeterminar la asociación entre la gravedad del asma medida por la puntuación Pediatric Respiratory Assessment Measure (PRAM) y la probabilidad de ingreso de los pacientes pediátricos que acuden al servicio de urgencias (SU) por exacerbaciones de asma moderado‐grave y que reciben tratamiento intensivo para el asma. MetodologíaAnálisis secundario de ...
Source: Academic Emergency Medicine - August 30, 2014 Category: Emergency Medicine Authors: Fuad Alnaji, Roger Zemek, Nick Barrowman, Amy Plint Tags: Original Contribution Source Type: research

Do primary care physicians coordinate ambulatory care for chronic disease patients in Canada?
Conclusion: The findings suggest that the current primary care system in Manitoba may not adequately support coordination of ambulatory care. Ambulatory visits to a primary care provider who is not the patient's regular provider may represent a lost opportunity for coordination and continuity of care, and may affect the quality of care patients receive. Primary care renewal initiatives in this province should address this challenge to service provision. (Source: BMC Family Practice)
Source: BMC Family Practice - August 30, 2014 Category: Primary Care Authors: Alan KatzPatricia MartensDan ChateauBodgan BogdanovicIna Koseva Source Type: research

Note: Page numbers of article titles are in boldface type. Acute respiratory failure, ventilatory support during sleep in COPD patients after, 386–387 (Source: Sleep Medicine Clinics)
Source: Sleep Medicine Clinics - August 29, 2014 Category: Sleep Medicine Source Type: research

Opioids, Sedatives, and Sleep Hypoventilation
The emphasis on improved pain control and the focus on treating chronic pain syndromes have led to a large increase in the number of patients on chronic opioid medications. The use of opioids chronically is associated with a variety of breathing disorders and potential for fatal outcomes. Understanding the mechanisms underlying control of respiration and opioid-mediated respiratory depression is essential in applying treatment options and providing new directions for management without sacrificing adequate pain control. (Source: Sleep Medicine Clinics)
Source: Sleep Medicine Clinics - August 29, 2014 Category: Sleep Medicine Authors: Nevin Arora, Michelle Cao, Shahrokh Javaheri Source Type: research

Validation of the Sonomat: A Contactless Monitoring System Used for the Diagnosis of Sleep Disordered Breathing
Conclusion:These data indicate that the Sonomat was reliable and accurate for the diagnosis of OSA. The provision of audible breath sound/snoring replay permits more accurate quantification of snoring. It requires no patient attachment and can be performed in the home with minimal training.Citation:Norman MB, Middleton S, Erskine O, Middleton PG, Wheatley JR, Sullivan CE. Validation of the Sonomat: a contactless monitoring system used for the diagnosis of sleep disordered breathing. SLEEP 2014;37(9):1477-1487. (Source: Sleep)
Source: Sleep - August 29, 2014 Category: Sleep Medicine Source Type: research

How the placenta makes pregnant women vulnerable to influenza (Flu)
Introduction: Influenza remains one of the most important transmissible viral infections worldwide, causing a significant annual burden of illness. Pregnant women are particularly susceptible to influenza, with an increased risk of severe respiratory disease and death, despite modern medical care. (Source: Placenta)
Source: Placenta - August 29, 2014 Category: Reproduction Medicine Authors: Jorge M. Tolosa, Kristy Parsons, Peter Wark, Roger Smith Tags: Frontmatter Source Type: research

The pattern of infection and antibiotics use in terminal cancer patients.
CONCLUSIONS: Our study revealed that antibiotic therapy for terminal cancer patients should be on a clear rationale. We need further study to clarify if there is survival effect with antibiotic use or not. PMID: 25150130 [PubMed - in process] (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - August 29, 2014 Category: Cancer & Oncology Authors: Mohammed AA, Al-Zahrani AS, Sherisher MA, Alnagar AA, El-Shentenawy A, El-Kashif AT Tags: J Egypt Natl Canc Inst Source Type: research

Systematic review and meta‐analysis of the accuracy of clinical indicators for ineffective airway clearance
ConclusionThis systematic review showed that the variability in clinical indicators of ineffective airway clearance is related to differences in the clinical settings and patients. (Source: Journal of Advanced Nursing)
Source: Journal of Advanced Nursing - August 29, 2014 Category: Nursing Authors: Vanessa Emille Carvalho Sousa, Marcos Venícios de Oliveira Lopes, Viviane Martins Silva Tags: Systematic Review Source Type: research

Compliance with Recommendations on Outpatient Antibiotic Prescribing for Respiratory Tract Infections: The Case of Spain
This study aimed at describing the current pattern of outpatient antibiotic use in acute RTIs in Spain and evaluating adherence to national recommendations. A retrospective observational study was performed including all the episodes of RTIs registered during a 1‐year period in a north‐eastern Spanish region. Data related to patient demography, diagnoses and antibiotic prescriptions were collected from the electronic medical history database in the region, and adherence to recommendations for antibiotic prescribing was assessed. One third of patients with a RTI were prescribed an antibiotic, with young adults (aged 15...
Source: Basic and Clinical Pharmacology and Toxicology - August 29, 2014 Category: Drugs & Pharmacology Authors: Sara Malo, Lars Bjerrum, Cristina Feja, María‐Jesús Lallana, Javier Moliner, María‐José Rabanaque Tags: Original Article Source Type: research

A Comparison of Short-Term Growth During Treatment with Two Dry Powder Combinations of Inhaled Corticosteroids and Long-Acting β2-Agonists
Journal of Aerosol Medicine and Pulmonary Drug Delivery , Vol. 0, No. 0. (Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery)
Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery - August 29, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Vagal tone as a biomarker of long‐term memory for a stressful social event at 4 months
This study investigates infants' memory for social stress after a 15‐day retention interval using behavior and respiratory sinus arrhythmia (RSA). Experimental group infants were exposed to face‐to‐face still‐face paradigm (FFSF) two times; the first time at 4 months and after a 2‐week interval. Control group infants were exposed to FFSF only once at 4 months plus 2 weeks. Infants were categorized as suppressors or non‐suppressors based on the direction of RSA change at first FFSF exposure. No behavioral differences were found among groups and exposure conditions. In the experimental group suppressors changed a...
Source: Developmental Psychobiology - August 29, 2014 Category: Psychiatry & Psychology Authors: Rosario Montirosso, Livio Provenzi, Ed Tronick, Francesco Morandi, Gianluigi Reni, Renato Borgatti Tags: Research Article Source Type: research

Roche to buy InterMune for respiratory boost
$8.3bn deal gives Roche a leading position in pulmonary fibrosis (Source: Chemistry World | Latest News)
Source: Chemistry World | Latest News - August 29, 2014 Category: Chemistry Authors: Sarah Houlton Source Type: research

Exclusive breastfeeding is associated with reduced cow's milk sensitization in early childhood
ConclusionsResults of this study suggest that exclusive breastfeeding is associated with a reduced risk of cow's milk protein sensitization during early childhood. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - August 29, 2014 Category: Allergy & Immunology Authors: Sui‐Ling Liao, Shen‐Hao Lai, Kuo‐Wei Yeh, Yu‐Lin Huang, Tsung‐Chieh Yao, Ming‐Han Tsai, Men‐Chin Hua, Jing‐Long Huang, Tags: Original Article Source Type: research

Cross‐sectional comparison of the characteristics of respiratory allergy in immigrants and Italian children
ConclusionsImmigrant children born either in Italy or abroad did not show significant differences in the clinical pattern of the respiratory allergic disease when compared to children born from Italian parents. (Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - August 29, 2014 Category: Allergy & Immunology Authors: Carlo Lombardi, Alessandro Fiocchi, Elena Raffetti, Francesco Donato, Giorgio Walter Canonica, Giovanni Passalacqua, Tags: Original Article Source Type: research

Infants under 6 months with bronchiolitis are most likely to need major medical interventions in the 5 days after onset
ConclusionInfants under 6 months of age with bronchiolitis were most likely to need MMIs in the first 5 days after disease onset. (Source: Acta Paediatrica)
Source: Acta Paediatrica - August 29, 2014 Category: Pediatrics Authors: H Pruikkonen, M Uhari, T Dunder, T Pokka, M Renko Tags: Regular Article Source Type: research

High-frequency oscillatory ventilation in adults: handle with care
In the previous issue of Critical Care, Gu and colleagues reported the results of a systematic review and meta-analysis of randomized trials comparing high-frequency oscillatory ventilation (HFOV) with conventional ventilation in adults with acute respiratory distress syndrome (ARDS). In contrast to findings of prior meta-analyses, their main finding was that, despite reducing risks of oxygenation failure, HFOV does not improve survival in adults with ARDS. (Source: Critical Care)
Source: Critical Care - August 29, 2014 Category: Intensive Care Authors: Niall Ferguson Source Type: research

Long-term Effects of Caffeine Therapy for Apnea of Prematurity on Sleep at School-age.
Conclusions: Therapeutic neonatal caffeine administration has no long-term effects on sleep duration or sleep apnea during childhood. Ex-preterm infants, regardless of caffeine status, are at risk for obstructive sleep apnea and periodic limb movements in later childhood. Clinical trial registration available at, ID NCT01020357. PMID: 25171195 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - August 29, 2014 Category: Respiratory Medicine Authors: Marcus CL, Meltzer LJ, Roberts RS, Traylor J, Dix J, D'ilario J, Asztalos E, Opie G, Doyle LW, Biggs SN, Nixon GM, Narang I, Bhattacharjee R, Davey M, Horne RS, Cheshire M, Gibbons J, Costantini L, Bradford R, Schmidt B, for the Caffeine for Apnea of Tags: Am J Respir Crit Care Med Source Type: research

National, state, and selected local area vaccination coverage among children aged 19-35 months - United States, 2013.
This report describes national, regional, state, and selected local area vaccination coverage estimates for children born January 2010-May 2012, based on results from the 2013 NIS. In 2013, vaccination coverage achieved the 90% national Healthy People 2020 target* for ≥1 dose of measles, mumps, and rubella vaccine (MMR) (91.9%); ≥3 doses of hepatitis B vaccine (HepB) (90.8%); ≥3 doses of poliovirus vaccine (92.7%); and ≥1 dose of varicella vaccine (91.2%). Coverage was below the Healthy People 2020 targets for ≥4 doses of diphtheria, tetanus, and pertussis vaccine (DTaP) (83.1%; target 90%); ≥4 doses of pneumoc...
Source: MMWR Morb Mortal Wkl... - August 29, 2014 Category: Epidemiology Authors: Elam-Evans LD, Yankey D, Singleton JA, Kolasa M, Immunization Services Division, National Center for Immunization and Respiratory Diseases, CDC Tags: MMWR Morb Mortal Wkly Rep Source Type: research

4D CT amplitude binning for the generation of a time-averaged 3D mid-position CT scan.
Abstract The purpose of this study was to develop a method to use amplitude binned 4D-CT (A-4D-CT) data for the construction of mid-position CT data and to compare the results with data created from phase-binned 4D-CT (P-4D-CT) data. For the latter purpose we have developed two measures which describe the regularity of the 4D data and we have tried to correlate these measures with the regularity of the external respiration signal.4D-CT data was acquired for 27 patients on a combined PET-CT scanner. The 4D data were reconstructed twice, using phase and amplitude binning. The 4D frames of each dataset were registered...
Source: Physics in Medicine and Biology - August 29, 2014 Category: Physics Authors: Kruis MF, van de Kamer JB, Belderbos JS, Sonke JJ, van Herk M Tags: Phys Med Biol Source Type: research

Spirometric reference values for healthy Han children aged 5–15 years in Guangzhou, Southern China
ConclusionsThe present spirometric reference equations are feasible for assessment of lung function among children in southern China. Further studies for establishment of reference values for Chinese children in other regions are needed. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - August 28, 2014 Category: Respiratory Medicine Authors: Mei Jiang, Yi Gao, Nan‐Shan Zhong, Wei‐Qing Chen, Wei‐Jie Guan, Jin‐Ping Zheng Tags: Original Article: Pulmonary Physiology Source Type: research

Back to Basics: Positioning the Patient
Positioning the surgical patient requires special attention from the entire surgical team because anesthetized or sedated patients are not able to reposition themselves when needed to relieve discomfort or alert team members of the need for repositioning. Perioperative nurses must pay attention to positioning details and the possibility of injury at all times during the patient’s procedure. This includes assessing the patient’s circulatory, respiratory, integumentary, musculoskeletal, and neurological structures to help ensure that the patient is properly positioned and safe from injury. (Source: AORN Journal)
Source: AORN Journal - August 28, 2014 Category: Nursing Authors: Lisa Spruce, Sharon A. Van Wicklin Tags: Featured Articles Source Type: research

Roche To Buy Intermune
Acquisition: Swiss drugmaker expands in respiratory disease field with $8.3 billion purchase of one-drug firm (Source: Chemical and Engineering News)
Source: Chemical and Engineering News - August 28, 2014 Category: Chemistry Authors: Ann M. Thayer Source Type: research

Is the incidence of aliphatic amine‐induced occupational rhinitis and asthma underestimated?
ConclusionsThe frequency of amine‐induced OR/OA may be underestimated, particularly when cleaning products are incriminated. Comprehensive investigation of all cases is mandatory to ensure an efficient prevention policy and consequently a good clinical and socio‐occupational prognosis of occupational respiratory disease. Am. J. Ind. Med. 9999:1–8, 2014. © 2014 Wiley Periodicals, Inc. (Source: American Journal of Industrial Medicine)
Source: American Journal of Industrial Medicine - August 28, 2014 Category: Occupational Health Authors: Hervé Laborde‐Castérot, Nicole Rosenberg, Patricia Dupont, Robert Garnier Tags: Research Article Source Type: research

A symptom-related monitoring program following pulmonary embolism for the early detection of CTEPH: a prospective observational registry study
Conclusion: A follow-up program based on telephone monitoring of symptoms and further structured evaluation of symptomatic subjects can detect patients with CTEPH. CPET may serve as a complementary diagnostic tool. (Source: BMC Pulmonary Medicine - Latest articles)
Source: BMC Pulmonary Medicine - Latest articles - August 28, 2014 Category: Respiratory Medicine Authors: Matthias HeldAlexander HesseFranziska GöttRegina HollGudrun HübnerPhilipp KolbHeinz LangenTobias RomenFranziska WalterHans SchäfersHeinrike WilkensBerthold Jany Source Type: research

DOORS syndrome: Phenotype, genotype and comparison with Coffin‐Siris syndrome
DOORS syndrome (Deafness, Onychodystrophy, Osteodystrophy, mental Retardation, Seizures) is characterized mainly by sensorineural deafness, shortened terminal phalanges with small nails of hands and feet, intellectual deficiency, and seizures. Half of the patients with all clinical features have mutations in TBC1D24. We review here the manifestations of patients clinically diagnosed with DOORS syndrome. In this cohort of 32 families (36 patients) we detected 13 individuals from 10 families with TBC1D24 mutations. Subsequent whole exome sequencing in the cohort showed the same de novoSMARCB1 mutation (c.1130G>A), known t...
Source: American Journal of Medical Genetics Part C: Seminars in Medical Genetics - August 28, 2014 Category: Genetics & Stem Cells Authors: Philippe M. Campeau, Raoul C. Hennekam, Tags: Research Article Source Type: research

Helicobacter pylori and Extragastric Diseases
Abstract While Helicobacter pylori infection was initially revealed to be associated only with some gastroduodenal diseases, further studies have shown its possible role in several extragastric diseases. For idiopathic thrombocytopenic purpura, sideropenic anemia, and vitamin B12 deficiency, the diagnosis of H. pylori infection is recommended, and there are many other conditions such as cardiovascular, neurological, dermatological, and respiratory diseases in which H. pylori may possibly play a role. Interestingly, a potential role has also been described for GI neoplastic diseases, including colorectal and pancreatic ca...
Source: Helicobacter - August 28, 2014 Category: Gastroenterology Authors: Francesco Franceschi, Annalisa Tortora, Giovanni Gasbarrini, Antonio Gasbarrini Tags: Review Article Source Type: research

Correlation between levels of exhaled hydrogen sulfide and airway inflammatory phenotype in patients with chronic persistent asthma
ConclusionsExhaled H2S may be a useful marker of airway inflammation in asthma. (Source: Respirology)
Source: Respirology - August 28, 2014 Category: Respiratory Medicine Authors: Jing Zhang, Xinmao Wang, Yahong Chen, Wanzhen Yao Tags: Original Article Source Type: research

Caring for Critically Ill Patients with Ebola Virus Disease: Perspectives from West Africa.
Villar RC, Shindo N, Bausch D Abstract The largest ever Ebola virus disease outbreak is ravaging West Africa. The constellation of little public health infrastructure, low levels of health literacy, limited acute care and infection prevention and control resources, densely populated areas and a highly transmissible, lethal viral infection, have led to over 2000 confirmed, probable or suspected cases and, thus far, more than 1000 deaths. Ebola virus disease is characterized by a febrile severe illness, with profound gastrointestinal manifestations, and is complicated by intravascular volume depletion, shock, profou...
Source: American Journal of Respiratory and Critical Care Medicine - August 28, 2014 Category: Respiratory Medicine Authors: Fowler RA, Fletcher T, Fischer Ii WA, Lamontagne F, Jacob S, Brett-Major D, Lawler JV, Jacquerioz FA, Houlihan C, O'Dempsey T, Ferri M, Adachi T, Lamah MC, Bah EI, Mayet T, Schieffelin J, McLellan SL, Senga M, Kato Y, Clement C, Mardel S, Vallenas Bejar D Tags: Am J Respir Crit Care Med Source Type: research

Socio-demographic vulnerability to heatwave impacts in Brisbane, Australia: a time series analysis.
Conclusions: Heat-related ED visits increased during heatwaves. However, due to overlapping confidence intervals, variations across socioeconomic areas should be interpreted cautiously. Implications: ED data may be utilised for monitoring heat-related health impacts, particularly on the first day of heatwaves, to facilitate prompt interventions and targeted resource allocation. PMID: 25169903 [PubMed - as supplied by publisher] (Source: Australian and New Zealand Journal of Public Health)
Source: Australian and New Zealand Journal of Public Health - August 28, 2014 Category: Global & Universal Authors: Sam Toloo G, Guo Y, Turner L, Qi X, Aitken P, Tong S Tags: Aust N Z J Public Health Source Type: research

Retrospective Review Of Combined Sirolimus And Simvastatin Therapy In Lymphangioleiomyomatosis.
Conclusions.Therapy with sirolimus and simvastatin does not increase the prevalence of drug adverse events or alter the therapeutic effects of sirolimus. Background.: Combined simvastatin and sirolimus therapy reduce TSC2-null lesions and alveolar destruction in a mouse model of lymphangioleiomyomatosis (LAM), suggesting that therapy with both drugs may benefit LAM patients. Methods.: To determine whether simvastatin changed the prevalence of adverse events or altered the therapeutic effects of sirolimus, we recorded adverse events and changes in lung function in LAM patients treated with simvastatin plus sirolimus...
Source: Chest - August 28, 2014 Category: Respiratory Medicine Authors: Taveira-DaSilva AM, Jones AM, Julien-Williams P, Stylianou M, Moss J Tags: Chest Source Type: research

Nurse Practitioner/Physician Assistant Staffing and Critical Care Mortality.
Conclusions:NP/PAs appear to be a safe adjunct to the ICU team, supporting NP/PA management of the critically ill. Background: Intensive care units (ICUs) are increasingly staffed with nurse practitioners/ physician assistants (NP/PAs) but it is unclear how they influence quality of care. We examined the association between NP/PA staffing and in-hospital mortality for ICU patients. Methods: We used retrospective cohort data from the 2009-2010 Acute Physiology and Chronic Health Evaluation clinical information system and an ICU-level survey. We included patients (≥ 17 years of age) admitted to one of 29 adult medi...
Source: Chest - August 28, 2014 Category: Respiratory Medicine Authors: Costa DK, Wallace DJ, Barnato AE, Kahn JM Tags: Chest Source Type: research

The impact of lung cancer on survival of Idiopathic Pulmonary Fibrosis.
CONCLUSIONIn patients with IPF LC has a significant adverse impact on survival. Diagnosis and treatment of LC in IPF are burdened by an increased incidence of severe complicating events, apparently as lethal as the cancer itself. BACKGROUND: Lung cancer (LC) is frequently associated with idiopathic pulmonary fibrosis (IPF), despite this well-known association the outcome of LC in IPF patients is unclear. The objective of this study was to evaluate the impact of LC on survival of patients with associated IPF. METHODS: A total of 260 patients with IPF were reviewed and 186 IPF cases had complete clinical and follow-u...
Source: Chest - August 28, 2014 Category: Respiratory Medicine Authors: Tomassetti S, Gurioli C, Ryu J, Decker P, Ravaglia C, Tantalocco P, Buccioli M, Piciucchi S, Sverzellati N, Dubini A, Gavelli G, Chilosi M, Poletti V Tags: Chest Source Type: research

Delirium detection using EEG: what and how to measure?
Conclusions:In a homogenous population of non-sedated cardiothoracic surgery patients, we observed that relative delta power from an eyes-closed EEG recording with only two electrodes in a frontal-parietal derivation can distinguish post-cardiothoracic surgery patients with delirium from those without. Background: Despite its frequency and impact, delirium is poorly recognized in postoperative- and critically ill patients. EEG (electroencephalography) is highly sensitive to delirium, but as currently used, it is not diagnostic. To develop an EEG-based tool for delirium detection with a limited number of electrodes, we ...
Source: Chest - August 28, 2014 Category: Respiratory Medicine Authors: van der Kooi AW, Zaal IJ, Klijn FA, Koek HL, Meijer RC, Leijten FS, Slooter AJ Tags: Chest Source Type: research

Socioeconomic inequalities in smoking habits are still increasing in Italy
Conclusion: Smoking prevalence has declined in Italy during the last decade among the higher socioeconomic classes, but not among the lower. This enlarging socioeconomic inequality mainly reflects a different trend in smoking initiation. (Source: BMC Public Health - Latest articles)
Source: BMC Public Health - Latest articles - August 27, 2014 Category: Consumer Health News Authors: Giuseppe VerlatoSimone AccordiniGiang NguyenPierpaolo MarchettiLucia CazzolettiMarcello FerrariLeonardo AntonicelliFrancesco AttenaValeria BellisarioRoberto BonoLamberto BriziarelliLucio CasaliAngelo Guido CorsicoAlessandro FoisMariaGrazia PanicoPavilio P Source Type: research

Out of the frying pan into the fire--the never forgiving complex congenital heart: a case of liquefied splenic infarct post-electrophysiology ablation
A 36-year-old man born with pulmonary atresia intact ventricular septum, atrial septal defect and Ebstein anomaly with hypoplastic right heart (figure 1 and online supplementary video). Waterson shunt had been performed in childhood, but over a period of time it had occluded with pulmonary circulation being dependent on bronchopulmonary collaterals. He is on targeted therapy for pulmonary hypertension. He was symptomatic with intermittent focal atrial tachycardia, despite amiodarone therapy. Coumarin therapy was avoided due to risk of massive haemoptysis. At electrophysiology, he had an atrial flutter circuit, which was re...
Source: Heart Asia - August 27, 2014 Category: Cardiology Authors: Rafiq, I., Deaville-Lees, D., Freeman, L. J. Tags: Images in cardiovascular medicine Source Type: research

Nasal and ocular amyloidosis in a 15-year-old horse
Localized nasal, conjunctival and corneal amyloidosis was diagnosed in a 15-year-old pony with nasal and conjunctival masses and severe dyspnoea. Multiple swellings had been evident in the nostrils for at least two years and had gradually increased in size before presentation due to dyspnoea and exercise intolerance. Surgical debulking of the masses was performed and histological examination revealed large amounts of extracellular, hyaline, eosinophilic, Congo red positive material in the lamina propria of the nasal mucosa. A tentative diagnosis of localized nasal amyloidosis was made. The treatment relieved the clinical s...
Source: Acta Veterinaria Scandinavica - August 27, 2014 Category: Veterinary Research Authors: Liv ØstevikGjermund GunnesGustavo de SouzaTale WienRandi Sørby Source Type: research

Purified deoxynivalenol or feed restriction reduces mortality in rainbow trout, Oncorhynchus mykiss (Walbaum), with experimental bacterial coldwater disease but biologically relevant concentrations of deoxynivalenol do not impair the growth of Flavobacterium psychrophilum
Abstract Diets containing deoxynivalenol (DON) were fed to rainbow trout Oncorhynchus mykiss (Walbaum) for 4 weeks followed by experimental infection (intraperitoneal) with Flavobacterium psychrophilum (4.1 × 106 colony‐forming units [CFU] mL−1). Mortality of rainbow trout fed either 6.4 mg kg−1 DON or trout pair‐fed the control diet was significantly reduced (P < 0.05) in comparison with trout fed the control diet to apparent satiation (<0.1 mg kg−1 DON). In a second experiment, trout were fed one of three experimental diets; a control diet, a diet produced with corn naturally contaminated with ...
Source: Journal of Fish Diseases - August 27, 2014 Category: Zoology Authors: I A Ryerse, J M Hooft, D P Bureau, M A Hayes, J S Lumsden Tags: Original Article Source Type: research

Complete coding regions of the prototypes enterovirus B93 and C95: Phylogenetic analyses of the P1 and P3 regions of EV‐B and EV‐C strains
Complete coding regions were sequenced for two new enterovirus genomes: EV‐B93 previously identified by VP1 sequencing, derived from a child with acute flaccid paralysis in the Democratic Republic of Congo; and EV‐C95 from a French soldier with acute gastroenteritis in Djibouti. The EV‐B93 P1 had more than 30% nucleotide divergence from other EV‐B types, with highest similarity to E‐15 and EV‐B80. The P1 nucleotide sequence of EV‐C95 was most similar, 71%, to CV‐A21. Complete coding regions for the new enteroviruses were compared with those of 135 EV‐B and 176 EV‐C strains representing all types availab...
Source: Journal of Medical Virology - August 27, 2014 Category: Virology Authors: N. Junttila, N. Lévêque, L.O. Magnius, J.P. Kabue, J. J. Muyembe‐Tamfum, J. Maslin, B. Lina, H. Norder Tags: Research Article Source Type: research