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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 2.

Impact of indoor air pollution from the use of solid fuels on the incidence of life threatening respiratory illnesses in children in India
Conclusion: The findings of this paper provide conclusive evidence on the harmful effects of the use of solid fuels for cooking on LTRI in India. The Government of India must make people aware about the health risks associated with the use of solid fuels for cooking and strive to promote the use of cleaner fuels. (Source: BMC Public Health)
Source: BMC Public Health - March 28, 2015 Category: Consumer Health News Authors: Ashish UpadhyayAbhishek SinghKaushalendra KumarAshish Singh Source Type: research

Benign outcome among positive cystic fibrosis newborn screen children with non-CF-causing variants
The Clinical and Functional Translation of CFTR project (CFTR2) classified some cystic fibrosis transmembrane conductance regulator (CFTR) gene variants as non-cystic fibrosis (CF)-causing. To evaluate this, the clinical status of children carrying these mutations was examined. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - March 28, 2015 Category: Respiratory Medicine Authors: Danieli Barino Salinas, Patrick R. Sosnay, Colleen Azen, Suzanne Young, Karen S. Raraigh, Thomas G. Keens, Martin Kharrazi Tags: Original Article Source Type: research

Atlantoaxial Subluxation and Nasopharyngeal Necrosis Complicating Suspected Granulomatosis With Polyangiitis
We report a case of suspected granulomatosis with polyangiitis limited to the nasopharynx. With a negative ANCA and no histological evidence, our diagnosis was founded on the exclusion of other diagnoses and the response to cyclophosphamide therapy. This case is unique because the patient’s lesion resulted in atlantoaxial instability, which required a posterior spinal fusion at C1–C2. This is the first reported case of suspected GPA producing damage to the cervical spine and threatening the spinal cord. (Source: JCR: Journal of Clinical Rheumatology)
Source: JCR: Journal of Clinical Rheumatology - March 27, 2015 Category: Rheumatology Tags: Medical Student Report Source Type: research

Aetiology of bronchiectasis in Guangzhou, southern China
ConclusionsIdiopathic, post‐infectious and immunodeficiency constitute major bronchiectasis aetiologies in Guangzhou. Clinical characteristics of patients between known aetiologies and idiopathic bronchiectasis were similar. Ethnicity and geography only account for limited differences in aetiologic spectra. These findings will offer rationales for early diagnosis and management of bronchiectasis in future studies and clinical practice in China. (Source: Respirology)
Source: Respirology - March 27, 2015 Category: Respiratory Medicine Authors: Wei‐jie Guan, Yong‐hua Gao, Gang Xu, Zhi‐ya Lin, Yan Tang, Hui‐min Li, Zhi‐min Lin, Jin‐ping Zheng, Rong‐chang Chen, Nan‐shan Zhong Tags: Original Article Source Type: research

Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease.
Abstract The source of the severe acute respiratory syndrome (SARS) epidemic was traced to wildlife market civets and ultimately to bats. Subsequent hunting for novel coronaviruses (CoVs) led to the discovery of two additional human and over 40 animal CoVs, including the prototype lineage C betacoronaviruses, Tylonycteris bat CoV HKU4 and Pipistrellus bat CoV HKU5; these are phylogenetically closely related to the Middle East respiratory syndrome (MERS) CoV, which has affected more than 1,000 patients with over 35% fatality since its emergence in 2012. All primary cases of MERS are epidemiologically linked to the M...
Source: Clinical Microbiology Reviews - March 27, 2015 Category: Microbiology Authors: Chan JF, Lau SK, To KK, Cheng VC, Woo PC, Yuen KY Tags: Clin Microbiol Rev Source Type: research

Los Angeles phonospirometry technique: creating a normogram that correlates with peak expiratory flow measurements in children
Journal of Asthma, Ahead of Print. (Source: Journal of Asthma)
Source: Journal of Asthma - March 27, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Associations of Pre-Transplant Prescription Narcotic Use with Clinical Complications after Kidney Transplantation
Conclusion: Although associations may reflect underlying conditions or behaviors, high-level prescription narcotic use before kidney transplantation predicts increased risk of clinical complications after transplantation.Am J Nephrol 2015;41:165-176 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 27, 2015 Category: Neurology Source Type: research

A pitfall in diagnosing Cushing’s disease: ectopic ACTH-producing pituitary adenoma in the sphenoid sinus
Conclusion Ectopic pituitary adenoma tissue causing Cushing’s disease is extremely rare but a potential cause for surgical failure or re-evaluation. (Source: Pituitary)
Source: Pituitary - March 27, 2015 Category: Endocrinology Source Type: research

Bacterial Lysate Increases the Percentage of Natural Killer T Cells in Peripheral Blood and Alleviates Asthma in Children
Conclusion: BV combined with conventional asthma treatment can prevent recurrent respiratory tract infections and suppress the severity of asthma attacks, possibly by altering the rates and cytokines of NKT cells.Pharmacology 2015;95:139-144 (Source: Pharmacology)
Source: Pharmacology - March 27, 2015 Category: Drugs & Pharmacology Source Type: research

Two Studies on Reversal of Opioid-Induced Respiratory Depression by BK-Channel Blocker GAL021 in Human Volunteers
No abstract available (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - March 27, 2015 Category: Anesthesiology Tags: Pharmacology Source Type: research

Preoperative Statin Administration Does Not Protect Against Early Postoperative Acute Respiratory Distress Syndrome: A Retrospective Cohort Study
No abstract available (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - March 27, 2015 Category: Anesthesiology Tags: Preoperative and Postoperative Care Source Type: research

Effects of Neostigmine Reversal of Nondepolarizing Neuromuscular Blocking Agents on Postoperative Respiratory Outcomes: A Prospective Study
No abstract available (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - March 27, 2015 Category: Anesthesiology Tags: Pharmacology Source Type: research

Mechanical Ventilation-Associated Lung Fibrosis in Acute Respiratory Distress Syndrome: A Significant Contributor to Poor Outcome
No abstract available (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - March 27, 2015 Category: Anesthesiology Tags: Critical Care Source Type: research

Long-term Survival in Patients With Severe Acute Respiratory Distress Syndrome and Rescue Therapies for Refractory Hypoxemia
No abstract available (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - March 27, 2015 Category: Anesthesiology Tags: Critical Care Source Type: research

(129) The use of a non-invasive respiratory volume monitor to identify patients at high-risk for opioid-induced respiratory depression for a low-dose opioid regimen in the PACU
The use of opioids in the management of post-operative pain management strikes a delicate balance between effective pain control and maintaining adequate respiratory function. The introduction of patient controlled analgesia (PCA) has allowed for prompt delivery of pain medication at the onset of pain. Unfortunately, the use of PCA has not eliminated the incidence of opioid-induced respiratory depression (OIRD) as real-time quantitative measurements of respiratory status are not routinely present. (Source: The Journal of Pain)
Source: The Journal of Pain - March 27, 2015 Category: Materials Science Authors: C. Voscopoulos, D. Ladd, E. George Source Type: research

(276) Tetrodotoxin attenuates thermal hyperalgesia in a rat full thickness thermal injury pain model
Burn injuries have been identified as the primary cause of injury in 5% of U.S. military personnel evacuated from Operations Iraqi Freedom and Enduring Freedom. Severe burn-associated pain is typically treated with opioids such as fentanyl (94.1% of patients in ISR Burn unit), morphine (90.1%), and methadone (87.1%). Side effects of opioids include the development of hyperalgesia, addiction, inflammation, respiratory depression, nausea and sedation. These effects have led us to search for novel analgesics for the treatment of burn-associated pain in wounded warriors. (Source: The Journal of Pain)
Source: The Journal of Pain - March 27, 2015 Category: Materials Science Authors: J. Clifford, M. Salas, M. McIntyre, D. Wong Source Type: research

(282) The development of mechanical allodynia after spinal cord injury is associated with higher respiratory rate
Chronic neuropathic pain and impaired autonomic signaling are major consequences of spinal cord injury (SCI). Despite the prevalence of these maladaptive conditions, the underlying mechanisms are poorly understood. C low threshold mechanoreceptors (C-LTMRs; CT afferents in human) are unmyelinated cutaneous afferents that were recently shown to normally encode pleasant touch, although under painful conditions, they can signal mechanical allodynia. In rodents, C-LTMRs innervating hairy skin can be selectively identified by their expression of tyrosine hydroxylase (TH). (Source: The Journal of Pain)
Source: The Journal of Pain - March 27, 2015 Category: Materials Science Authors: S. Garraway, K. Watkins, S. Hochman Source Type: research

(331) Acute tolerance to opioid-induced respiratory depression after fentanyl and morphine administration
Opioids cause untoward side effects, the most pronounced being respiratory depression, which limit their therapeutic use as analgesics. Studies have shown that acute analgesic tolerance to fentanyl is dependent on mu-opioid receptor (MOR) inactivation thru GRK3/arrestin signaling, whereas acute tolerance to morphine is contingent on JNK2 and arrestin-independent signaling in mice. However it is largely unknown whether there is acute tolerance to opioid-induced respiratory depression, and if tolerance to respiratory depression is dependent on MOR inactivation through GRK3 or JNK2-mediated signaling. (Source: The Journal of Pain)
Source: The Journal of Pain - March 27, 2015 Category: Materials Science Authors: C. Nwaneshiudu, M. Emery, J. Levin, C. Chavkin, G. Terman Tags: E27 Opioid Action Source Type: research

(366) Efficacy of flurbiprofen 8.75 mg spray in patients with relatively severe sore throat symptoms
Patients with pharyngitis often report severe sore throat symptoms. We evaluated the efficacy of a single dose of flurbiprofen 8.75 mg spray in patients with relatively severe symptoms at baseline. This randomised, double-blind, multicentre study enrolled patients with recent onset (≤4 days) sore throat due to an upper respiratory tract infection, ≥5 points on the 21-point Tonsillo-Pharyngitis Assessment (TPA), ≥6 points on the 11-point Throat Soreness Scale (TSS), ≥50 mm on the 100-mm Difficulty Swallowing Scale (DSS) and ≥33 mm on the 100-mm Swollen Throat Scale (SwoTS). (Source: The Journal of Pain)
Source: The Journal of Pain - March 27, 2015 Category: Materials Science Authors: M. Russo, F. de Looze, M. Bloch, B. Montgomery, G. Smith, A. Shephard, S. Aspley Source Type: research

(418) Subanesthetic doses of ketamine produce respiratory depression in patients receiving methadone, but not in controls or patients receiving other long-term opioids
NMDA receptor antagonists are known to transiently reverse opioid tolerance and enhance analgesia. However, NMDA antagonists have not been reported to produce respiratory depression, when administered to patients receiving long-term opioid therapy. Patients treated with long-term opioid therapy (LTOT) are often difficult to sedate for endoscopic procedures, and frequently require anesthesia support. Ketamine/propofol sedation is often utilized at our institution, as it has been shown to minimize respiratory depression, maintain oxygenation, and provide better operating conditions, than fentanyl/midazolam sedation. (Source:...
Source: The Journal of Pain - March 27, 2015 Category: Materials Science Authors: H. Burgess, K. Fragoza, R. Faizan, A. Siddiqui, F. Burgess Tags: F16 Opioids - Clinical Pharmacology Source Type: research

Molecular responses in the telomere-mitochondrial axis of ageing in the elderly: A candidate gene approach
Publication date: January 2015 Source:Mechanisms of Ageing and Development, Volume 145 Author(s): Nicky Pieters , Bram G. Janssen , Linda Valeri , Bianca Cox , Ann Cuypers , Harrie Dewitte , Michelle Plusquin , Karen Smeets , Tim S. Nawrot Experimental evidence shows that telomere shortening induces mitochondrial damage but so far studies in humans are scarce. Here, we investigated the association between leukocyte telomere length (LTL) and mitochondrial DNA (mtDNA) content in elderly and explored possible intermediate mechanisms by determining the gene expression profile of candidate genes in the telomere-mitochondrial ...
Source: Mechanisms of Ageing and Development - March 27, 2015 Category: Geriatrics Source Type: research

Immediate delivery versus expectant monitoring for hypertensive disorders of pregnancy between 34 and 37 weeks of gestation (HYPITAT-II): an open-label, randomised controlled trial
This study is registered with the Netherlands Trial Register (NTR1792). Findings Between March 1, 2009, and Feb 21, 2013, 897 women were invited to participate, of whom 703 were enrolled and randomly assigned to immediate delivery (n=352) or expectant monitoring (n=351). The composite adverse maternal outcome occurred in four (1·1%) of 352 women allocated to immediate delivery versus 11 (3·1%) of 351 women allocated to expectant monitoring (relative risk [RR] 0·36, 95% CI 0·12–1·11; p=0·069). Respiratory distress syndrome was diagnosed in 20 (5·7%) of 352 neonates in the immediate delivery group versus six (1·7%...
Source: The Lancet - March 27, 2015 Category: Journals (General) Source Type: research

Is the Glasgow Coma Scale Score in Children in the Emergency Department Lower During the Night?
Discussion The presentation of children with low GCS scores was more common during the night. Children with reduced GCS scores and viral respiratory tract infections presented more frequently during the night. Assessment of patients’ level of consciousness during the night needs to discriminate difficulties in eliciting a response due to fatigue from features of cerebral dysfunction. (Source: Journal of Emergency Nursing)
Source: Journal of Emergency Nursing - March 27, 2015 Category: Nursing Source Type: research

Accès des sages-femmes libérales au plateau technique : l’expérimentation d’une maternité de type 1
Discussion et conclusion L’accès au plateau technique apparaît comme une opportunité permettant à la sage-femme libérale de nouer une relation privilégiée avec sa patiente. Ce dispositif préserve toutefois la possibilité d’une prise en charge traditionnelle hospitalière en cas de nécessité. En ce sens, l’accès au plateau technique est une alternative sûre qui a l’assentiment des patientes, des sages-femmes comme de l’ensemble de notre équipe hospitalière. Ce dispositif a par ailleurs permis un surcroît d’activité obstétricale de 5 % par an pour notre service et laisse présager un gain de 10...
Source: Gynecologie Obstetrique and Fertilite - March 27, 2015 Category: OBGYN Source Type: research

Home-use servo-ventilation therapy in chronic pain patients with central sleep apnea: initial and 3-month follow-up
Conclusions Initial and home use of ASV for 3 months resulted in significantly lower AHI, CAI, and OAI. This reduction attests to the efficacy of ASV treatment in chronic pain patients on high doses of opioids. (Source: Sleep and Breathing)
Source: Sleep and Breathing - March 27, 2015 Category: Respiratory Medicine Source Type: research

Pulmonary artery diastolic pressure gradient as an indicator of severity of illness in patients with pulmonary hypertension related to left-sided heart disease
Discussion: Among patients with Group 2 PH, elevated DPG proved to be a more specific indicator of worse functional status than the historically used TPG. International guidelines and protocols for performing RHC for the assessment and diagnosis of PH should include the measurement of DPG. (Source: Therapeutic Advances in Respiratory Disease)
Source: Therapeutic Advances in Respiratory Disease - March 27, 2015 Category: Respiratory Medicine Authors: Howard, C., Rangajhavala, K., Safdar, Z. Tags: Original Research Source Type: research

Efficacy and safety profile of autologous blood versus tetracycline pleurodesis for malignant pleural effusion
Conclusions: ABP was as effective as tetracycline in the treatment of MPE. ABP produced less pain and fever, and could shorten the hospital stay. (Source: Therapeutic Advances in Respiratory Disease)
Source: Therapeutic Advances in Respiratory Disease - March 27, 2015 Category: Respiratory Medicine Authors: Keeratichananont, W., Limthon, T., Keeratichananont, S. Tags: Original Research Source Type: research

Combination therapy with indacaterol and glycopyrronium bromide in the management of COPD: an update on the evidence for efficacy and safety
The international guidelines on chronic obstructive pulmonary disease (COPD) recommend inhaled bronchodilators for maintenance treatment of the disease. These drugs include β2-agonists and muscarinic antagonists, which are both available as short-acting agents (to be used as needed for dyspnea) and long-acting agents. To the latter belong salmeterol and formoterol (long-acting β2-agonists) and indacaterol, vilanterol and olodaterol (very long-acting β2-agonist) as β2-agonists, and tiotropium, aclidinium and glycopyrronium bromide as long-acting muscarinic antagonists. The efficacy and safety of indacate...
Source: Therapeutic Advances in Respiratory Disease - March 27, 2015 Category: Respiratory Medicine Authors: Ridolo, E., Montagni, M., Riario-Sforza, G. G., Baroni, M., Incorvaia, C. Tags: Reviews Source Type: research

Clinicopharmacological profile of the fixed-dose combination of aclidinium bromide and formoterol fumarate in the management of chronic obstructive pulmonary disease
The recent Global Initiative for Chronic Obstructive Lung Disease (GOLD) chronic obstructive pulmonary disease (COPD) guidelines consider symptoms and exacerbation history in addition to the degree of airflow obstruction for classifying patients. The improvement of symptoms is principally provided by bronchodilators, using β2 agonists and antimuscarinic agents. Aclidinium bromide is a novel long-acting antimuscarinic agent licensed for use in patients with COPD. Novel fixed-dose combinations that are either licensed or in their late phase of development include vilanterol/umeclidinium, indacaterol/glycopyrronium, olod...
Source: Therapeutic Advances in Respiratory Disease - March 27, 2015 Category: Respiratory Medicine Authors: Babu, K. S., Morjaria, J. B. Tags: Reviews Source Type: research

Tracheobronchopathia Osteochondroplastica: Case Report and Literature Review
Publication date: Available online 26 March 2015 Source:Respiratory Medicine Case Reports Author(s): Junping Sun , Lixin Xie , Xianling Su , Xingang Zhang Tracheobronchopathia osteochondroplastica (TPO) is a rare disorder characterized as multiple osseous or cartilaginous nodules in the submucosa of trachea and main bronchi. TPO remains an under recognized entity due to lack of awareness. Four cases of TPO are reported in this review as well as various facets of TPO description. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - March 27, 2015 Category: Respiratory Medicine Source Type: research

Autophagy Activation and Protection From Mitochondrial Dysfunction in Human Chondrocytes
ConclusionOur data highlight the role of autophagy as a critical protective mechanism against mitochondrial dysfunction. Pharmacologic interventions that enhance autophagy may have chondroprotective activity in cartilage degenerative processes such as OA. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - March 27, 2015 Category: Rheumatology Authors: Paloma López de Figueroa, Martin K. Lotz, Francisco J. Blanco, Beatriz Caramés Tags: Chondrocyte Biology Source Type: research

Mutation in MRPS34 Compromises Protein Synthesis and Causes Mitochondrial Dysfunction
by Tara R. Richman, Judith A. Ermer, Stefan M. K. Davies, Kara L. Perks, Helena M. Viola, Anne-Marie J. Shearwood, Livia C. Hool, Oliver Rackham, Aleksandra Filipovska The evolutionary divergence of mitochondrial ribosomes from their bacterial and cytoplasmic ancestors has resulted in reduced RNA content and the acquisition of mitochondria-specific proteins. The mitochondrial ribosomal protein of the small subunit 34 (MRPS34) is a mitochondria-specific ribosomal protein found only in chordates, whose function we investigated in mice carrying a homozygous mutation in the nuclear gene encoding this protein. The Mrps34 mutat...
Source: PLoS Genetics - March 27, 2015 Category: Genetics & Stem Cells Authors: Tara R. Richman et al. Source Type: research

Exercise Intensity Modulates Capillary Perfusion in Correspondence with ACE I/D Modulated Serum Angiotensin II Levels
Publication date: Available online 27 March 2015 Source:Applied & Translational Genomics Author(s): Sander van Ginkel , Arnold de Haan , Jorn Woerdeman , Luc Vanhees , Erik Serné , Jos de Koning , Martin Flück During exercise the renin-angiotensin system is stimulated. We hypothesized that the increase in serum angiotensin II (AngII) levels after exercise is dependent on exercise intensity and duration and secondly that people with the ACE-II genotype will show a higher increase in AngII serum levels. We also assumed that perfusion of upper limbs is transiently reduced with maximal cycling exercise and that sub...
Source: Applied and Translational Genomics - March 27, 2015 Category: Genetics & Stem Cells Source Type: research

Fibronectin in the palatine tonsil as a susceptibility marker in Egyptian rheumatic families: Histological and immunohistochemical studies
Rheumatic fever (RF) and rheumatic heart disease (RHD) are the multisystem autoimmune sequel of group A streptococci (GAS) infection of the upper respiratory passages, mainly tonsillopharyngitis. The major receptor on the surface of human palatine tonsil for GAS is fibronectin (FN; adhesin receptor). Early detection of RF susceptibility is considered as an important aim of this study. Therefore, the present study aimed to use FN immunoreactivity (FN-ir) as a marker for early detection of rheumatic susceptible children with palatine tonsil crypts surface epithelium. A total of 30 palatine tonsillar specimens were obtained f...
Source: Toxicology and Industrial Health - March 27, 2015 Category: Toxicology Authors: Gazia, M. A., Tousson, E., El-Fatah, M. A., Shoheib, A. S. Tags: Articles Source Type: research

Thermogenic Capacity of Brown Adipocytes [Bioenergetics]
To determine the differences between brown adipocytes from interscapular brown tissue (iBAT) and those induced in white adipose tissue (WAT) with respect to their thermogenic capacity, we examined two essential characteristics: the dynamics of mitochondrial turnover during reversible transitions from 29 °C to 4 °C and the quantitative relationship between UCP1 and selected subunits of mitochondrial respiratory complex in the fully recruited state. To follow the kinetics of induction and involution of mitochondria, we determined the expression pattern of UCP1 and other mitochondrial proteins as well as analyzed mtDNA cont...
Source: Journal of Biological Chemistry - March 27, 2015 Category: Chemistry Authors: Gospodarska, E., Nowialis, P., Kozak, L. P. Tags: Metabolism Source Type: research

Tracheobronchial Brush Cytology and Bronchoalveolar Lavage in Dogs and Cats with Chronic Cough: 45 Cases (2012–2014)
Conclusions and clinical relevanceBrush cytology has good agreement with BAL regarding the presence of inflammation, although the type of inflammation detected with the different sampling techniques commonly varies. Brush cytology can provide supplementary information to BAL, and additional studies will provide further information on the role of tracheobronchial brush cytology in the diagnosis and management of respiratory conditions. (Source: Journal of Veterinary Internal Medicine)
Source: Journal of Veterinary Internal Medicine - March 27, 2015 Category: Veterinary Research Authors: B.Y. Zhu, L.R. Johnson, W. Vernau Tags: Standard Article Source Type: research

Co‐infections with Respiratory Viruses in Dogs with Bacterial Pneumonia
Conclusion and Clinical ImportanceRespiratory viruses were found frequently in dogs with BP and may therefore play an important role in the etiology and pathogenesis of BP. Clinical variables and disease severity did not differ between BP dogs with and without viral co‐infection. (Source: Journal of Veterinary Internal Medicine)
Source: Journal of Veterinary Internal Medicine - March 27, 2015 Category: Veterinary Research Authors: S.J. Viitanen, A. Lappalainen, M.M. Rajamäki Tags: Standard Article Source Type: research

Clinical Severity Score System in Dogs with Degenerative Mitral Valve Disease
Conclusions and Clinical ImportanceRoutinely obtained clinical findings allow risk stratification of dogs with DMVD. Results of ancillary diagnostic tests may be complementary to history and PE findings and always should be interpreted in conjunction with these findings. (Source: Journal of Veterinary Internal Medicine)
Source: Journal of Veterinary Internal Medicine - March 27, 2015 Category: Veterinary Research Authors: J. López‐Alvarez, J. Elliott, D. Pfeiffer, Y.‐M. Chang, M. Mattin, W. Moonarmart, M.J. Hezzell, A. Boswood Tags: Standard Article Source Type: research

Mannheimia haemolytica in Feedlot Cattle: Prevalence of Recovery and Associations with Antimicrobial Use, Resistance, and Health Outcomes
Conclusions and Clinical ImportanceResistance generally was rare in M. haemolytica. Antimicrobial drug exposures in penmates increased the risk of isolating susceptible and multiply‐resistant M. haemolytica, a finding that could be explained by contagious spread. (Source: Journal of Veterinary Internal Medicine)
Source: Journal of Veterinary Internal Medicine - March 27, 2015 Category: Veterinary Research Authors: N.R. Noyes, K.M. Benedict, S.P. Gow, C.W. Booker, S.J. Hannon, T.A. McAllister, P.S. Morley Tags: Standard Article Source Type: research

The impact of obesity on pediatric procedural sedation‐related outcomes: results from the Pediatric Sedation Research Consortium
ConclusionsObesity is an independent risk factor for adverse respiratory events during procedural sedation and is associated with an increased frequency of airway interventions, suggesting that additional vigilance and expertise are required when sedating these patients. (Source: Pediatric Anesthesia)
Source: Pediatric Anesthesia - March 27, 2015 Category: Anesthesiology Authors: Patricia D. Scherrer, Michael M. Mallory, Joseph P. Cravero, Lia Lowrie, James H. Hertzog, John W. Berkenbosch, Tags: Original Article Source Type: research

An ethnobotanical survey of medicinal plants in western part of central Taurus Mountains: Aladaglar (Nigde – Turkey)
Conclusion The use of traditional medicine was still widespread among the inhabitants of Aladaglar mountains/Nigde region. Due to the lack of medical facilities in the villages of Aladaglar mountains, local people prefer herbal treatment rather than medical treatment. This study identified not only the wild plants collected for medical purposes by local people of Aladaglar/Nigde, but also the uses and local names of these plants. This paper helps to preserve valuable information that may otherwise be lost to future generations. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - March 27, 2015 Category: Drugs & Pharmacology Source Type: research

A huge traumatic pulmonary pseudocyst: A case report
We report a 26-year-old male patient who presented to the emergency room with internal bleeding and shock. Huge TPP (14 cm in diameter) was seen on whole-body computed tomography scan and complicated with bronchial bleeding. He deteriorated to respiratory failure soon after arriving at the emergency room. TPPs imply high-energy impact on the chest region and frequently complicated with pulmonary contusions, hemo- and pneumo-thorax, multiple rib fractures, flail chest, and concurrent with abdominal injuries. Emergency physicians should be aware of such rare entity and manage correctly. (Source: Journal of Acute Medicine)
Source: Journal of Acute Medicine - March 27, 2015 Category: Emergency Medicine Source Type: research

Information and Communication Technology–Enabled Person-Centered Care for the “Big Five” Chronic Conditions: Scoping Review
Conclusions: This scoping review outlined ICT-enabled PCC in chronic disease management. Persons with a chronic disease could benefit from an ICT-enabled PCC approach, but ICT-PCC also yields organizational paybacks. It could lead to an increase in health care usage, as reported in some studies. Few interventions could be regarded as “fully” addressing PCC. This review will be especially helpful to those deciding on areas where further development of research or implementation of ICT-enabled PCC may be warranted. (Source: Journal of Medical Internet Research)
Source: Journal of Medical Internet Research - March 27, 2015 Category: Journals (General) Authors: Sabine E WildevuurLianne WL Simonse Source Type: research

Assessment of PaO2/FiO2 for stratification of patients with moderate and severe acute respiratory distress syndrome
Conclusions Our findings support the need for patient assessment under SVS at 24 h after ARDS onset to assess disease severity, and have implications for the diagnosis and management of ARDS patients. Trial registration numbers NCT00435110 and NCT00736892. (Source: BMJ Open)
Source: BMJ Open - March 27, 2015 Category: Journals (General) Authors: Villar, J., Blanco, J., del Campo, R., Andaluz-Ojeda, D., Diaz-Dominguez, F. J., Muriel, A., Corcoles, V., Suarez-Sipmann, F., Tarancon, C., Gonzalez-Higueras, E., Lopez, J., Blanch, L., Perez-Mendez, L., Fernandez, R. L., Kacmarek, R. M., for the Spanish Tags: Open access, Intensive care, Respiratory medicine Research Source Type: research