Medicine RSS Search Engine

Respiratory Medicine Respiratory Medicine RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 2.

Askin tumour in pregnancy with dismal prognosis
Abstract Askin tumor is a rare malignant neoplasm of the chest wall. A 23 year old primigravida patient was admitted to the hospital with complaints of chest wall swelling, cough & dyspnea. Radiological examination showed a chest wall mass in right hemithorax with erosion of ribs and moderate pleural effusion. Fine needle aspiration cytology was suggestive of malignant small round cell tumor. Immunohistochemical analysis together with the clinical and radiological findings led to the definitive diagnosis of Askin tumor. Despite receiving multimodality therapy, she had residual soft tissue mass and died after six months...
Source: The Clinical Respiratory Journal - October 29, 2014 Category: Respiratory Medicine Authors: Kiranjit Sidhu, Surender Kashyap, R.S. Negi, Anjali Solanki Tags: Other Source Type: research

An Evaluation of Neuromuscular Electrical Stimulation in Critical Care Using the Icf Framework: a Systematic Review and Meta‐Analysis
ConclusionNMES, as an adjunct to current rehabilitation practices in critically ill patients may maintain muscle strength. However, high quality studies with longer follow‐up periods and standardised outcome measures across all domains of the ICF framework are required. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 29, 2014 Category: Respiratory Medicine Authors: Dearbhla Burke, Emma Gorman, Diarmaid Stokes, Olive Lennon Tags: Review Article Source Type: research

Outcomes Treating Stage Iii Non‐Small Cell Lung Carcinoma with Curative‐Intent Radiotherapy and Concurrent Carboplatin‐Paclitaxel Chemotherapy
ConclusionTreatment with thoracic radiotherapy and concurrent carboplatin and paclitaxel chemotherapy is feasible. Survival and toxicity outcomes compare favorably to those reported using cisplatin‐based regimens. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 29, 2014 Category: Respiratory Medicine Authors: Trinh Hon M, Pinkham Mark B, Lehman Margot, Zarate Dannie, Dauth Margaret, McGrath Margaret, McCaffrey Elizabeth, Mai Gang Tao, Horwood Keith Tags: Original Article Source Type: research

Does a Nintendo Wii exercise program provide similar exercise demands as a traditional pulmonary rehabilitation program in adults with COPD?
ConclusionGaming technology can provide an exercise program that has similar cardiovascular demand to traditional pulmonary rehabilitation programs for patients with COPD. Further research is necessary to address feasibility and long‐term adherence. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 29, 2014 Category: Respiratory Medicine Authors: Tyler LeGear, Mark LeGear, Dejan Preradovic, Geoffrey Wilson, Ashley Kirkham, Pat G Camp Tags: Original Article Source Type: research

Monoclonal IgG1κ Anti–Glomerular Basement Membrane Disease: A Case Report
We report a case of anti–glomerular basement membrane (anti-GBM) nephritis with indolent course, monoclonal IgG1κ (immunoglobulin G, subclass 1, κ light chain) linear staining of the GBM, and multifocal GBM breaks but without crescents or detectable serum anti-GBM antibody in a patient followed over 9 years. Atypically, anti-GBM nephritis follows an indolent course. A very small fraction of patients with anti-GBM nephritis lack detectable circulating anti-GBM antibodies, and rare reports of monoclonal anti-GBM nephritis exist. We report what is to our knowledge the first case manifesting all three of these rare variati...
Source: American Journal of Kidney Diseases - October 29, 2014 Category: Urology & Nephrology Source Type: research

The Effect of the Pressure-Volume Curve for Positive End-Expiratory Pressure Titration on Clinical Outcomes in Acute Respiratory Distress Syndrome: A Systematic Review
Conclusion This analysis supports an association that ventilator management guided by the PVC for PEEP management may augment survival in ARDS. Nonetheless, only 3 randomized trials have addressed the question, and the total number of patients remains low. Further outcomes studies appear required for the validation of this methodology. (Source: Journal of Intensive Care Medicine)
Source: Journal of Intensive Care Medicine - October 29, 2014 Category: Intensive Care Authors: Hata, J. S., Togashi, K., Kumar, A. B., Hodges, L. D., Kaiser, E. F., Tessmann, P. B., Faust, C. A., Sessler, D. I. Tags: Review of a Large Clinical Series Source Type: research

The Prevalence and Impact of Mortality of the Acute Respiratory Distress Syndrome on Admissions of Patients With Ischemic Stroke in the United States
Conclusion: Our analysis demonstrates that ARDS is rare after AIS. Despite an overall significant reduction in mortality after AIS, ARDS carries a higher risk of death in this patient population. (Source: Journal of Intensive Care Medicine)
Source: Journal of Intensive Care Medicine - October 29, 2014 Category: Intensive Care Authors: Rincon, F., Maltenfort, M., Dey, S., Ghosh, S., Vibbert, M., Urtecho, J., Jallo, J., Ratliff, J. K., McBride, J. W., Bell, R. Tags: Original Research Source Type: research

Characteristics and Outcomes of HIV-1-infected Patients with Acute Respiratory Distress Syndrome
We determined the prevalence of risk factors for the development of acute respiratory distress syndrome (ARDS), outcomes of critical illness, and the impact of HAART in HIV-1-infected patients. We hypothesized that in an urban county hospital, HIV-1-infected patients with ARDS would have a higher mortality than their HIV-1-uninfected counterparts. (Source: Journal of Critical Care)
Source: Journal of Critical Care - October 29, 2014 Category: Intensive Care Authors: Freny J. Nirappil, Ana Maheshwari, Joel Andrews, Greg S. Martin, Annette M. Esper, Sushma K. Cribbs Source Type: research

Conditionally induced RAGE expression by proximal airway epithelial cells in transgenic mice causes lung inflammation
Conclusions: These data support the concept that RAGE up-regulation specifically in lung airways may function in the progression of proximal airway inflammation. (Source: Respiratory Research)
Source: Respiratory Research - October 29, 2014 Category: Respiratory Medicine Authors: B BodineBrock BennionEmma LeathamFelix JimenezAlex WrightZac JergensenConnor EricksonCameron JonesJeff JohnsonSteven KnappPaul Reynolds Source Type: research

The prevalence of increased serum IgE and Aspergillus sensitization in patients with COPD and their association with symptoms and lung function
Conclusions: There was a high prevalence of elevated serum T-IgE and AH in patients with COPD. Serum T-IgE level was correlated with symptoms such as dyspnea and impairment of lung function. Allergens other than Aspergillus may have similar effects on disease expression or progression of COPD. (Source: Respiratory Research)
Source: Respiratory Research - October 29, 2014 Category: Respiratory Medicine Authors: Jianmin JinXiaofang LiuYongchang Sun Source Type: research

Aeromedical evacuation of combat patients by military critical care air transport teams with a lower hemoglobin threshold approach is safe
CONCLUSIONEvacuating CCATT patients with an Hgb of 8 or less had similar adverse outcomes and mortality at 30 days compared with those with an Hgb greater than 8. Patients with an Hgb of 7 or less had higher rates of hospital discharge and decreased incidence of hospitalization at 30 days. LEVEL OF EVIDENCEPrognostic/epidemiologic study, level III. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - October 28, 2014 Category: Surgery Tags: Original Articles Source Type: research

Damage-control thoracic surgery: Management and outcomes
CONCLUSIONPatients with severe chest trauma and marked physiologic derangement can benefit from damage-control thoracic surgery. Thoracic packing and temporary vacuum closure avoids thoracic compartment syndrome. Timing of thoracic closure is based on physiology. While complications were common, mortality is acceptable in this group of severely injured, metabolically depleted, challenging patients. LEVEL OF EVIDENCETherapeutic study, level V. (Source: Journal of Trauma and Acute Care Surgery)
Source: Journal of Trauma and Acute Care Surgery - October 28, 2014 Category: Surgery Tags: AAST 2013 Plenary Papers Source Type: research

, a surprising and stealthy osteoarticular pathogen
Kingella kingae has gained a conspicuous place in the roster of pathogens of osteoarticular infections in young children. In many countries K kingae is the most common etiology of joint infections in children 6 to 48 months of age. Known to colonize the upper respiratory tract and transmit readily in children in daycare, the role of K kingae's in osteoarticular infections frequently is only confirmed by special care to inoculate tissue and fluid specimens into liquid media or through molecular diagnostic testing. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - October 28, 2014 Category: Pediatrics Authors: Sarah S. Long Tags: The Editors' Perspectives Source Type: research

Pertussis in the Newborn: certainties and uncertainties in 2013
Bordetella pertussis infection carries a high risk of mortality in newborns and vulnerable unimmunized young infants. The disease may develop a fulminant course characterized by pneumonia that rapidly evolves to respiratory failure with refractory hypoxemia, pulmonary hypertension, extreme leukocytosis and cardiogenic shock requiring cardiovascular support An outbreak is now under way and it is time to recognize the successes of the past and to implement new directions for the control of pertussis. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - October 28, 2014 Category: Respiratory Medicine Authors: Gustavo Rocha, Paulo Soares, Henrique Soares, Susana Pissarra, Hercília Guimarães Source Type: research

Effect of preterm birth on exercise capacity: A systematic review and meta‐analysis
ConclusionDespite marked deficits in spirometry, preterm‐born children have a marginally decreased , which is unlikely to be of great clinical significance. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - October 28, 2014 Category: Respiratory Medicine Authors: Martin O. Edwards, Sarah J. Kotecha, John Lowe, W. John Watkins, A. John Henderson, Sailesh Kotecha Tags: Review Source Type: research

Safety and immunogenicity of a novel cold‐adapted modified‐live equine influenza virus vaccine
ObjectiveTo design and evaluate the safety and immunogenicity of a modified‐live vaccine to prevent equine influenza virus (EIV) infection based on the novel reassortant cold‐adapted strain A/HK/Otar/6:2/2010. MethodsSurface proteins (HA, NA) from the wild‐type strain A/equine/Otar/764/2007 (H3N8) and internal proteins (PB2, PB1, PA, NP, M, NS) from the attenuated cold‐adapted donor strain A/Hong Kong/1/68/162/35CA (H3N2) were included in the vaccine. Horses were administered 109.2 EID50/mL of the modified‐live vaccine or saline solution using a nasal spray. The clinical condition of the animals was assessed thro...
Source: Australian Veterinary Journal - October 28, 2014 Category: Veterinary Research Authors: K Tabynov, Z Kydyrbayev, S Ryskeldinova, N Assanzhanova, Y Kozhamkulov, D Inkarbekov, A Sansyzbay Tags: EQUINE Source Type: research

Determination of ‘recruited volume’ following a PEEP step is not a measure of lung recruitability
ConclusionOur findings suggest that RecV predominately measures a slow fraction of inflation of already aerated lung tissue and not recruitment of collapsed alveoli. (Source: Acta Anaesthesiologica Scandinavica)
Source: Acta Anaesthesiologica Scandinavica - October 28, 2014 Category: Anesthesiology Authors: C. A. STAHL, K. MÖLLER, D. STEINMANN, D. HENZLER, S. LUNDIN, O. STENQVIST Tags: Original Article Source Type: research

Effect of nicotine dependence on opioid requirements of patients after thoracic surgery
ConclusionsSmokers had more severe postoperative pain and required a higher quantity of postoperative opioid than nonsmokers. With increasing nicotine dependence, postoperative pain severity and postoperative opioid requirement increased. (Source: Acta Anaesthesiologica Scandinavica)
Source: Acta Anaesthesiologica Scandinavica - October 28, 2014 Category: Anesthesiology Authors: A. YU, X. CAI, Z. ZHANG, H. SHI, D. LIU, P. ZHANG, Z. FU Tags: Original Article Source Type: research

Perioperative management of carinal pneumonectomy: a retrospective review of 13 patients
This report describes our routine anesthetic and respiratory management strategy in patients undergoing carinal pneumonectomy. Medical records of 13 patients who underwent carinal pneumonectomy under combined general and epidural anesthesia between 2008 and 2012 were analyzed retrospectively. Eleven patients underwent right carinal pneumonectomy and two underwent left carinal pneumonectomy. A left double-lumen tube was used in all but one case, in which endobronchial intubation was difficult because of intrabronchial invasion of the tumor. A 6.0-mm-long reinforced endobronchial tube was intubated into the main bronchus of ...
Source: Journal of Anesthesia - October 28, 2014 Category: Anesthesiology Source Type: research

Considerations during intravenous sedation in geriatric dental patients with dementia
Conclusions All the scheduled dental treatments in dementia patients were smoothly performed under IVS. However, stringent attention should be paid to the prevention of aspiration of fluids retained in the pharynx, airway obstruction due to therapeutic maneuvers, respiratory inhibition by sedatives, and hemodynamic fluctuations caused by invasive procedures under local anesthesia. Clinical relevance In the future, with the growing need for dental procedures in dementia patients, dentists will require training in the general management of such patients. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - October 28, 2014 Category: Dentistry Source Type: research

Safety and efficacy of amphotericin-B deoxycholate inhalation in critically ill patients with respiratory Candida spp. colonization: a retrospective analysis
Background: Candida spp. are frequently cultured from the respiratory tract in critically ill patients. Most intensivists start amphotericin-B deoxycholate (ABDC) inhalation therapy to eradicate Candida spp. from the respiratory tract. However, the safety and efficacy of this treatment are not well established. The purpose of this study was to assess the safety and efficacy of ABDC inhalation for the treatment of respiratory Candida spp. colonization in critically ill patients. Methods: All non-neutropenic patients admitted into the intensive care unit (ICU) of a university hospital from December 2010?2011, who had positiv...
Source: BMC Infectious Diseases - October 28, 2014 Category: Infectious Diseases Authors: Patrick van der GeestErik DietersBart RijndersJohan Groeneveld Source Type: research

Isocapnic hyperpnea with a portable device in Cystic Fibrosis: an agreement study between two different set-up modalities
This study shows considerable discrepancies between the two methods, making the degree of agreement not clinically acceptable. This might cause inappropriate setting and disservice to patients with CF. (Source: Journal of Clinical Monitoring and Computing)
Source: Journal of Clinical Monitoring and Computing - October 28, 2014 Category: Information Technology Source Type: research

Oral care for intubated patients: a survey of intensive care unit nurses
ConclusionsThe nurses' attitudes towards oral care were generally positive and most oral care methods were appropriate. However, some methods and products used were inconsistent with the current recommendations and they have mixed views about the suitability of oral care supplies and equipment provided by the hospital. Relevance to clinical practiceRecommendations were made for providing standard oral care protocols for intubated patients and oral care training programs for ICU nurses to support delivery of quality patient care. (Source: Nursing in Critical Care)
Source: Nursing in Critical Care - October 28, 2014 Category: Nursing Authors: Norkhafizah Saddki, Farah Elani Mohamad Sani, Mon Mon Tin‐Oo Tags: Research Source Type: research

Effect of transnasal insufflation on sleep-disordered breathing in acute stroke
(Source: Sleep and Breathing)
Source: Sleep and Breathing - October 28, 2014 Category: Respiratory Medicine Source Type: research

Is the chronotype associated with obstructive sleep apnea?
Conclusion We demonstrated, for the first time, an age- and BMI-related effect of morning- and evening-types in OSA severity, suggesting that the intermediate chronotype might play a role as a protective factor in older and overweight patients. (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 28, 2014 Category: Respiratory Medicine Source Type: research

Atlas of Clinical Sleep Medicine , second edition, by Meir H. Kryger, Alon Y. Avidan, and Richard B. Berry, 511 pages, $165.30, ISBN: 978-0-323-18727-5; Elsevier, Saunders
(Source: Sleep and Breathing)
Source: Sleep and Breathing - October 28, 2014 Category: Respiratory Medicine Source Type: research

Long-term Effect of Vasodilator Therapy in Pulmonary Hypertension due to COPD: A Retrospective Analysis
Conclusion PH-target vasodilator therapy improved NYHA functional class and 6MWD up to one year in highly selected patients with severe PH-COPD. Poor exercise capacity, low SpO2 and high mean pulmonary artery pressure at baseline but not airflow obstruction were associated with unfavourable outcome. (Source: Lung)
Source: Lung - October 28, 2014 Category: Respiratory Medicine Source Type: research

The effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthma
Conclusions: Oral MEM 1414, a novel PDE4 inhibitor, significantly reduces the late response following inhaled allergen challenge. MEM 1414 also inhibited whole blood assays of cytokine production from inflammatory cells. MEM 1414 was associated with a typical adverse event profile of PDE4 inhibitors, namely nausea and vomiting although these were mild side effects.Trial registration number: Current controlled trials ISRCTN48047493. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - October 28, 2014 Category: Respiratory Medicine Authors: Brian LeakerDave SinghFerhana AliPeter BarnesBrian O¿Connor Source Type: research

Asthma and respiratory symptoms among hairdressers in Denmark: Results from a register based questionnaire study
ConclusionsAsthma and especially respiratory symptoms were commonly reported by hairdressers, but rarely reported as an occupational disease. Local exhaust ventilation was inconsistently used. Our results underline the need for improved measures to ascertain and prevent occupational asthma in hairdressers. Am. J. Ind. Med. © 2014 Wiley Periodicals, Inc. (Source: American Journal of Industrial Medicine)
Source: American Journal of Industrial Medicine - October 28, 2014 Category: Occupational Health Authors: Susan Hovmand Lysdal, Holger Mosbech, Jeanne Duus Johansen, Heidi Søsted Tags: Research Article Source Type: research

The role of pH-sensitive TASK channels in central respiratory chemoreception.
Abstract A number of the subunits within the family of K2P background K(+) channels are sensitive to changes in extracellular pH in the physiological range, making them likely candidates to mediate various pH-dependent processes. Based on expression patterns within several brainstem neuronal cell groups that are believed to function in CO2/H(+) regulation of breathing, three TASK subunits-TASK-1, TASK-2, and TASK-3-were specifically hypothesized to contribute to this central respiratory chemoreflex. For the acid-sensitive TASK-1 and TASK-3 channels, despite widespread expression at multiple levels within the brains...
Source: Pflugers Archiv : European Journal of Physiology - October 28, 2014 Category: Physiology Authors: Bayliss DA, Barhanin J, Gestreau C, Guyenet PG Tags: Pflugers Arch Source Type: research

Polyomaviruses-associated respiratory infections in HIV-infected and HIV-uninfected children
Lower respiratory tract-infections (LRTIs) are a major cause of hospitalizations during childhood [1]. Determining pathogen specific causality of LRTIs is hampered by lack of sensitive methods for diagnosing bacterial pneumonia, as well as the concurrent identification of multiple respiratory-viral pathogens, particularly when using molecular assays [2]. Nevertheless, worldwide studies attribute a large proportion of LRTIs to viral infections [3,4]. Large-scale molecular screening based technologies have contributed to the discovery of new infectious pathogens, including in 2007 two polyomaviruses (PyV), WU- and KI-polyoma...
Source: Journal of Clinical Virology - October 28, 2014 Category: Virology Authors: Marta C. Nunes, Zachary Kuschner, Zelda Rabede, Clare L. Cutland, Richard Madimabe, Locadiah Kuwanda, Keith P. Klugman, Peter V. Adrian, Shabir A. Madhi Source Type: research

priming by worms protects against respiratory allergies
The hygiene hypothesis forms a popular explanation for the increasing prevalence of inflammatory diseases, such as allergies, asthma, and autoimmune diseases, by stating that changes in the environment and lifestyle have resulted in decreased microbial exposure and a relatively weaker development of the regulatory arm of the immune system. Indeed, a number of examples have underscored the association between microbes and disease protection, such as studies on farm microbes, orofecal microorganisms, gut microbiota, and other ancient commensals, such as gut worms. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - October 28, 2014 Category: Allergy & Immunology Authors: Hermelijn H. Smits, Cezmi A. Akdis Tags: Editorial Source Type: research

Proprotein Convertase 5/6A is Associated with BMP-2-induced Squamous Cell Differentiation.
Abstract Squamous metaplasia in airway epithelium is a pathological process arising from abnormal remodeling/repair responses to injury. Proteolytic maturation of many growth and differentiation factors involved in tissue remodeling is controlled by proprotein convertases (PCs). However, the role of these convertases in airway remodeling remains poorly understood. Using a retinoic acid deficiency-induced squamous metaplasia model of cultured human nasal epithelial cells (HNECs), we observed a significant increase in the expression of PC5/6A, a PC member, and bone morphogenetic protein-2 (BMP-2), a candidate substra...
Source: American Journal of Respiratory Cell and Molecular Biology - October 28, 2014 Category: Molecular Biology Authors: Lee SN, Lee DH, Lee MG, Yoon JH Tags: Am J Respir Cell Mol Biol Source Type: research

The UCP2 ‐866 G>A promoter region polymorphism is associated with nonalcoholic steatohepatitis
ConclusionsUCP2 ‐866 A/A genotype is associated with increased hepatic UCP2 expression and reduced risk of nonalcoholic steatohepatitis, particularly in subjects with normal fasting glucose.This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - October 28, 2014 Category: Gastroenterology Authors: Roberta Fares, Salvatore Petta, Rosa Lombardi, Stefania Grimaudo, Paola Dongiovanni, Rosaria Pipitone, Raffaela Rametta, Anna Ludovica Fracanzani, Enrico Mozzi, Antonio Craxì, Silvia Fargion, Giorgio Sesti, Luca Valenti Tags: Original Article Source Type: research

Overview of preparedness and response for Middle East respiratory syndrome coronavirus (MERS-CoV) in Oman
(Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 28, 2014 Category: Infectious Diseases Authors: I.S. Al-Abaidani, A.S. Al-Maani, H.S. Al-Kindi, A.K. Al-Jardani, D.M. Abdel-Hady, B.E. Zayed, K.S. Al-Harthy, K.H. Al-Shaqsi, S.S. Al-Abri Source Type: research

Initial Respiratory Support with Cold, Dry Gas versus Heated Humidified Gas and Admission Temperature of Preterm Infants
To assess whether the addition of heated humidified gas (HHG) at delivery and until neonatal unit arrival improved admission temperatures of preterm infants. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - October 28, 2014 Category: Pediatrics Authors: Michael P. Meyer, David Hou, Nazmul N. Ishrar, Ingrid Dito, Arjan B. te Pas Tags: Original Article Source Type: research

Exuberant Varicella-Zoster Exanthema and Pneumonia as Clinical Clue for HIV Infection
A 4-year-old boy presented to the hospital in the sixth day of ongoing varicella infection with high fever, respiratory distress, and hypoxemia. Physical examination showed tachypnea, a generalized vesicular exanthema, perioral impetigo (Figure 1), bilateral rales, and diminished breath sounds at pulmonary auscultation. Chest radiograph revealed bilateral, multifocal, heterogeneous alveolar opacities with nodular pattern, reaching the periphery (Figure 2; available at www.jpeds.com). Blood testing showed 9.7 × 109/L white blood cells, 3.7 × 109/L neutrophils, 5.1 × 109/L lymphocytes with 7% reactive lymphocytes, C-r...
Source: The Journal of Pediatrics - October 28, 2014 Category: Pediatrics Authors: Filipa Mestre A. Dias, Filipa Marçal, Joana Oliveira, Marta Póvoas, Ana Mouzinho, José Gonçalo Marques Tags: Insights and Images Source Type: research

Digital Reconstruction of High-quality Daily 4D Cone-beam CT Images Using Prior Knowledge of Anatomy and Respiratory Motion
In radiation therapy, it is well known that patient anatomy can undergo significant changes, such as tumor shrinkage or expansion and weight loss, from the simulation phase to the delivery of radiation beam. Apparently, those changes cannot be fully compensated by rigid image alignment. Therefore, image guidance on a regular basis is critical to monitoring anatomic changes during the course of treatment. Although routine assessment of patient anatomy can generally be achieved using conventional CT, the advent of in-room cone-beam computed tomography (CBCT) [1–4] provides an accurate representation of patient anatomy prio...
Source: Computerized Medical Imaging and Graphics - October 28, 2014 Category: Radiology Authors: Yongbin Zhang, Jinzhong Yang, Lifei Zhang, Laurence E. Court, Song Gao, Peter A. Balter, Lei Dong Source Type: research

Options for Assessing and Measuring Chest Wall Motion
Assessing chest wall motion is a basic and vital component in managing the child with respiratory problems, whether these are due to pathology in the lungs, airways, chest wall or muscles. Since the 1960s, clinical assessment has been supplemented with an ever-growing range of technological options for measuring chest wall motion, each with unique advantages and disadvantages. Measurements of chest wall motion can be used to: (1) Assess respiratory airflow and volume change, as a non-invasive alternative to measurement at the airway opening, (2) Monitor breathing over long periods of time, to identify apnoea and other type...
Source: Paediatric Respiratory Reviews - October 28, 2014 Category: Respiratory Medicine Authors: Paul Seddon Source Type: research

A Randomized, Three-Period Crossover Study Of Umeclidinium As Monotherapy In Adult Patients With Asthma
To our knowledge, no studies in patients with asthma have assessed a long-acting muscarinic antagonist in the absence of inhaled corticosteroids (ICS). (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - October 28, 2014 Category: Respiratory Medicine Authors: Laurie A. Lee, Anne Briggs, Lisa D. Edwards, Shuying Yang, Steven Pascoe Source Type: research