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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 20.

Timing of Tuberculosis Transmission and the Impact of Household Contact Tracing: An Agent-Based Simulation Model.
Conclusions: Household contact tracing is unlikely to transform TB epidemiology in isolation but has the potential - especially with provision of preventive therapy - to augment a comprehensive package of interventions that could substantially reduce the population-level burden of TB. PMID: 24559425 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - February 21, 2014 Category: Respiratory Medicine Authors: Kasaie P, Andrews JR, Kelton WD, Dowdy DW Tags: Am J Respir Crit Care Med Source Type: research

Inappropriate prescribing of combination inhalers in Northern Ireland: retrospective cross-sectional cohort study of prescribing practice in primary care.
CONCLUSIONS: ICS/LABA therapy was initiated in the majority of young subjects with asthma without prior inhaled steroid therapy. Most prescriptions were initiated in the January to March period. However, the prescribing of ICS/LABA did not appear to be driven by asthma symptoms (17% received SABA in the previous 6 months) or severe asthma exacerbation (only 5% received oral steroids). Significant reductions in ICS/LABA, with associated cost savings, would occur if the asthma prescribing guidelines were followed in primary care. PMID: 24570080 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - February 21, 2014 Category: Respiratory Medicine Authors: Sweeney J, Patterson CC, O'Neill S, O'Neill C, Plant G, Lynch V, McAllister T, Heaney LG Tags: Prim Care Respir J Source Type: research

Pleural Effusion and Sarcoidosis: An Unusual Combination.
Abstract Pleural involvement in sarcoidosis is uncommon and appears in several forms. To document the incidence and characteristics of pleural effusion in sarcoidosis patients, a review of the cases diagnosed in our centre between January 2001 and December 2012 was carried out. One hundred and ninety-five patients with sarcoidosis were identified; three (two men and one woman) presented with unilateral pleural effusion (1.5%): one in the right side and two in the left. Two were in stageii and one was in stageiv. The pleural fluid of the two patients who underwent thoracocentesis was predominantly lymphocytic. One o...
Source: Archivos de Bronconeumologia - February 21, 2014 Category: Respiratory Medicine Authors: Ferreiro L, San José E, González-Barcala FJ, Suárez-Antelo J, Toubes ME, Valdés L Tags: Arch Bronconeumol Source Type: research

Respiratory muscle strength in healthy infants and those with surgically correctable anomalies
Summary Assessment of respiratory muscle strength provides important diagnostic and prognostic information. Normative data in healthy, term infants is, however, limited. Surgically correctable birth defects, congenital diaphragmatic hernia (CDH) and abdominal wall defects (AWD), commonly have impaired diaphragm function. The study aims were to obtain normative data for respiratory muscle strength in healthy, term born infants at birth and at 6 weeks postnatal age (PNA) and to investigate the influence of growth and maturation on inspiratory muscle strength in CDH/AWD infants. Maximal inspiratory (cPimax) and expiratory (cP...
Source: Pediatric Pulmonology - February 20, 2014 Category: Respiratory Medicine Authors: Zainab Kassim, John Moxham, Mark Davenport, Kypros Nicolaides, Anne Greenough, Gerrard F. Rafferty Tags: Original Article: Pulmonary Physiology Source Type: research

Cardiac arrest teams and medical emergency teams in Finland: a nationwide cross‐sectional postal survey
ConclusionsCurrent guidelines emphasise the preventative actions on in‐hospital cardiac arrest. Practices are changing accordingly but are still suboptimal especially in central and district hospitals. Unified guidelines on rapid response systems are required. (Source: Acta Anaesthesiologica Scandinavica)
Source: Acta Anaesthesiologica Scandinavica - February 20, 2014 Category: Anesthesiology Authors: J. TIRKKONEN, J. NURMI, K. T. OLKKOLA, J. TENHUNEN, S. HOPPU Tags: Original Article Source Type: research

Marijuana: Respiratory Tract Effects
(Source: Clinical Reviews in Allergy and Immunology)
Source: Clinical Reviews in Allergy and Immunology - February 20, 2014 Category: Allergy & Immunology Authors: Owen, KellySutter, MarkAlbertson, Timothy Source Type: research

Seasonal variation in basal metabolic rates among the yakut (Sakha) of Northeastern Siberia
Conclusions: Among the Yakut, increased wintertime BMR was observed among younger but not older adults, whereas all adults showed sharp reductions in free thyroid hormone levels during the winter. Among men, greater participation in subsistence activities was associated with increased BMRs and greater fat oxidation. Among women, variation in food use had the strongest impact on metabolic function. Am. J. Hum. Biol., 2014. © 2014 Wiley Periodicals, Inc. (Source: American Journal of Human Biology)
Source: American Journal of Human Biology - February 20, 2014 Category: Biology Authors: W.R. Leonard, S.B. Levy, L.A. Tarskaia, T.M. Klimova, V.I. Fedorova, M.E. Baltakhinova, V.G. Krivoshapkin, J.J. Snodgrass Tags: Original Article Source Type: research

Contaminants in human nail dust: an occupational hazard in podiatry?
Conclusion: The high levels of Aspergilus contamination is a significant finding in the podiatry group as this fungus is small enough to enter the tissue of the nasal cavity and as a small particle will stay airborne in the room for up to 16 hours. Aspergilus has been shown to cause brain and soft tissue tumours in extreme cases. The high levels of upper respiratory track problems reported in the literature may well be caused by this fungal agent. The non use and use of inappropriate masks by podiatrists is clearly an occupational hazard to their health and well being. (Source: Journal of Foot and Ankle Research)
Source: Journal of Foot and Ankle Research - February 20, 2014 Category: Podiatry Authors: Paul TinleyKaren EddyPeter Collier Source Type: research

Unusual complication of dental extraction: Lingual abscess
Lalee Varghese, Pratibha Agarwal, Vedantam RupaIndian Journal of Dental Research 2013 24(6):772-774Acute lingual swelling is a potentially life threatening clinical condition which is encountered very rarely, the differential diagnosis of which includes hemorrhage, infarction, abscess, tumor and edema. Herein we report a case of lingual abscess that presented with acute tongue swelling and respiratory distress after extraction of lower two incisor teeth. (Source: Table of Contents : Indian Journal of Dental Research : 2006 - 17(3))
Source: Table of Contents : Indian Journal of Dental Research : 2006 - 17(3) - February 20, 2014 Category: Dentistry Authors: Lalee VarghesePratibha AgarwalVedantam Rupa Source Type: research

Autocrine ligands of the epithelial growth factor receptor mediate inflammatory responses to diesel exhaust particles
Conclusion Expression of IL-8 in response to DEPs is dependent on EGFR activation and that autocrine production of EGFR ligands makes a substantial contribution to this response. Capsule Summary: This study identifies a mechanism whereby diesel particles stimulates IL-8 release from bronchial epithelial cells. This mechanism may help to explain the recruitment of neutrophils into the airways of people exposed to particulate air pollution. (Source: Respiratory Research)
Source: Respiratory Research - February 20, 2014 Category: Respiratory Medicine Authors: Sam ParniaLynnsey HamiltonSarah PuddicombeStephen HolgateAnthony FrewDonna Davies Source Type: research

Electromagnetic Navigation Guided TBNA Versus Conventional TBNA in the Diagnosis of Mediastinal Lymphadenopathy
ConclusionIn this study comparing ENB‐TBNA and C‐TBNA, the sampling and diagnostic success of ENB‐TBNA was found to be superior while dealing with MLN, in all categories studied. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 20, 2014 Category: Respiratory Medicine Authors: Özlem Erçen Diken, Demet Karnak, Aydın Çiledağ, Koray Ceyhan, Çetin Atasoy, Serdar Akyar, Oya Kayacan Tags: Original Article Source Type: research

Predicting malignant and tuberculous pleural effusions through demographics and pleural fluid analysis of patients
ConclusionsThe results obtained to estimate the probability of tuberculous and malignant pleural effusion confirm that this model achieves a high diagnostic accuracy. This model should be applied to determine which patients with a pleural effusion of unknown origin would not benefit from further invasive procedures. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 20, 2014 Category: Respiratory Medicine Authors: Luis Valdés, Esther San‐José, Lucía Ferreiro, Antonio Golpe, Francisco‐Javier González‐Barcala, María E. Toubes, María X. Rodríguez‐Álvarez, José M. Álvarez‐Dobaño, Nuria Rodríguez‐Núñez, Carlos Rábade, Francisco Gude Tags: Original Article Source Type: research

Comparison of clinical characteristics of chronic cough due to non‐acid and acid gastroesophageal reflux
ConclusionsThere are some differences in the clinical manifestations between non‐acid and acid GERC, but MII‐pH is essential to diagnose non‐acid GERC. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 20, 2014 Category: Respiratory Medicine Authors: Xianghuai Xu, Zhongmin Yang, Qiang Chen, Li Yu, Siwei Liang, Hanjing Lü, Zhongmin Qiu Tags: Original Article Source Type: research

Clinical relevance of positive human parechovirus type 1 and 3 PCR in stool samples
In conclusion, HPeV3 detected by PCR in stool samples is associated with clinically relevant disease. For HPeV1, a positive stool sample is mainly associated with symptoms in children with underlying disease. (Source: Clinical Microbiology and Infection)
Source: Clinical Microbiology and Infection - February 20, 2014 Category: Microbiology Authors: J. G. Wildenbeest, K. S. M. Benschop, R. P. Minnaar, S. Bouma‐de Jongh, K. C. Wolthers, D. Pajkrt Tags: Original Article Source Type: research

Clinical characteristics and quality of life in women with COPD: an observational study
Conclusions: This study underlines that despite less airflow limitation, quality of life is more impacted by chronic sputum in women than in men. (Source: BMC Women's Health - Latest articles)
Source: BMC Women's Health - Latest articles - February 20, 2014 Category: OBGYN Authors: Chantal RaherisonIsabelle Tillie-LeblondAnne PrudhommeCamille TailléElisabeth BironCecilia Nocent-EjnainiBenigne MathieuJuliette Ostinelli Source Type: research

In this issue of Occupational Medicine
(Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Meyer, J. Tags: In This Issue Source Type: research

Perspectives on active ageing and work-related stress in Europe: a European opinion poll
(Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Sedlatschek, C. Tags: Editorial Source Type: research

Rene Magritte, Golconda 1953
(Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: McKiernan, M. Tags: Art and occupation Source Type: research

Vestibular assessment: a practical approach
This paper presents an evidence-based introduction to assessing and managing the dizzy patient. It is based upon a literature review highlighting current best practice and the clinical experience of the author. Dizziness is common, often chronic and largely untreated, resulting in great personal and economic loss. Serious pathological causes of dizziness may be quickly and effectively screened by a simple ocular motor examination, differentiating these from peripheral vestibular lesions. A triage, differentiating dizziness into either acute onset, intermittent episodes or continuous symptoms is proposed, along with managem...
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Sealy, A. Tags: In-depth review Source Type: research

Fifty years ago: 'Free enterprise and public service'
(Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Tags: Filler Source Type: research

Employment in adults with cystic fibrosis
Conclusions Adults with CF reported that CF impacted on their ability to work. Employment appeared to be most strongly associated with educational attainment, locality and HRQoL domains and not clinical parameters of severity. Specific guidance is needed for both adults with CF and potential employers, with appropriate targeted interventions aimed at improving health perceptions and coping strategies. (Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Targett, K., Bourke, S., Nash, E., Murphy, E., Ayres, J., Devereux, G. Tags: Original Paper Source Type: research

Age-related injury and compensation claim rates in heavy industry
Conclusions These findings do not provide evidence to support the notion that older workers sustain more injuries and are more likely to claim compensation for their injuries. Our findings demonstrate that in this workplace, older workers were able to maintain their ability to work safely. This contrasts with the finding that younger workers had the highest injury and claim rates. While adapting to the needs of an ageing workforce, employers should not lose sight of the need to nurture a strong culture of working safely among their youngest workers. (Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Guest, M., Boggess, M. M., Viljoen, D. A., Duke, J. M., Culvern, C. N. Tags: Original Paper Source Type: research

Respiratory protective equipment reduces occurrence of sensitization to laboratory animals
Conclusions The use of simple RPE at first exposure to laboratory animals may help to reduce the incidence of specific sensitization. (Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Jones, M., Schofield, S., Jeal, H., Cullinan, P. Tags: Original Paper Source Type: research

Historical cohort study of shift work and blood pressure
Conclusions No significant association between SW and BP was observed among these three groups (day workers, weekly rotating shift workers and routinely rotating shift workers). Prospective studies, which control for confounding factors, such as the healthy worker effect, occupational history, family history and psychological factors (e.g. occupational stress and job satisfaction), are required to evaluate this further. (Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Gholami Fesharaki, M., Kazemnejad, A., Zayeri, F., Rowzati, M., Akbari, H. Tags: Original Paper Source Type: research

Work-related chemical exposures presenting to an emergency department in Singapore
Conclusions Work-related chemical exposures that present to the ED had low morbidity. Most of the workers did well with immediate decontamination and supportive treatment but antidotes were required for some exposures. (Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Tan, H. H., Teo, S., Tseng, H. C. Tags: Original Paper Source Type: research

Slips, trips and falls at a chemical manufacturing company
Conclusions Risk factors for STF in a large US chemical company are similar to those reported from other workplaces, but we found that staying fit and healthy is important for reducing risk. (Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Swaen, G., Burns, C. J., Collins, J. J., Bodner, K. M., Dizor, J. F., Craun, B. A., Bonner, E. M. Tags: Original Paper Source Type: research

Standards for 'Health for Health Professionals' services in the UK
Conclusions This study will assist discussion about providing and improving consistent services across the UK, while recognizing the flexibility required in view of geographical differences. (Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Cohen, D., Marfell, N., Greene, G. Tags: Original Paper Source Type: research

The effect of hand-arm vibration syndrome on quality of life
Conclusions Both the physical and the mental QOL in workers with HAVS were below Canadian population normal values and subjects’ upper extremity pain score had the greatest effect on their QOL. (Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: House, R., Wills, M., Liss, G., Switzer-McIntyre, S., Lander, L., Jiang, D. Tags: Original Paper Source Type: research

Bronchiolitis obliterans organizing pneumonia following nitric acid fume exposure
We describe a patient with clinical, radiological and pathological features of bronchiolitis obliterans organizing pneumonia. Investigation showed that this was likely to have been a delayed consequence of inhalation of nitric acid fumes (containing nitrogen dioxide) after a fire. This case shows that thorough investigation of the aetiology is important not only in clinical management but also in ensuring patients benefit from appropriate work injury compensation. (Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Lee, L. T., Ho, C. H. B., Putti, T. C. Tags: Case Report Source Type: research

Phq-9
(Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Williams, N. Tags: Questionnaire Review Source Type: research

Anorexia Nervosa: A Recovery Guide for Sufferers, Families and Friends
(Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Williams, N. Tags: Book Review Source Type: research

Current Topics in Occupational Epidemiology
(Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Poole, J. Tags: Book Review Source Type: research

Sickness and early retirement
(Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Authors: Noone, P. Tags: Monitor Source Type: research

Occupational Medicine Calendar
(Source: Occupational Medicine)
Source: Occupational Medicine - February 20, 2014 Category: Respiratory Medicine Tags: Calendar Source Type: research

Formaldehyde-Associated Changes in microRNAs: Tissue and Temporal Specificity in the Rat Nose, White Blood Cells, and Bone Marrow
MicroRNAs (miRNAs) are critical regulators of gene expression, yet much remains unknown regarding their changes resulting from environmental exposures as they influence cellular signaling across various tissues. We set out to investigate miRNA responses to formaldehyde, a critical air pollutant and known carcinogen that disrupts miRNA expression profiles. Rats were exposed by inhalation to either 0 or 2 ppm formaldehyde for 7, 28, or 28 days followed by a 7-day recovery. Genome-wide miRNA expression profiles were assessed within the nasal respiratory epithelium, circulating white blood cells (WBC), and bone marrow (BM). mi...
Source: Toxicological Sciences - February 20, 2014 Category: Toxicology Authors: Rager, J. E., Moeller, B. C., Miller, S. K., Kracko, D., Doyle-Eisele, M., Swenberg, J. A., Fry, R. C. Tags: Research Article Source Type: research

Influenza Vaccine Response in Adults Exposed to Perfluorooctanoate and Perfluorooctanesulfonate
Supported by several epidemiological studies and a large number of animal studies, certain polyfluorinated alkyl acids are believed to be immunotoxic, affecting particularly humoral immunity. Our aim was to investigate the relationship between the antibody response following vaccination with an inactivated trivalent influenza vaccine and circulating levels of perfluorooctanoate (PFOA) and perfluorooctanesulfonate (PFOS). The study population consisted of 411 adults living in the mid-Ohio region of Ohio and West Virginia where public drinking water had been inadvertently contaminated with PFOA. They participated in a larger...
Source: Toxicological Sciences - February 20, 2014 Category: Toxicology Authors: Looker, C., Luster, M. I., Calafat, A. M., Johnson, V. J., Burleson, G. R., Burleson, F. G., Fletcher, T. Tags: Research Article Source Type: research

Transcriptome Profiling of the Newborn Mouse Lung Response to Acute Ozone Exposure
This study was carried out to define the effect of acute ozone exposure on the neonatal lung and to profile the transcriptome response. Newborn mice were exposed to ozone or filtered air for 3h. Total RNA was isolated from lung tissues at 6 and 24h after exposure and was subjected to microarray gene expression analysis. Compared to filtered air-exposed littermates, ozone-exposed newborn mice developed a small but significant neutrophilic airway response associated with increased CXCL1 and CXCL5 expression in the lung. Transcriptome analysis indicated that 455 genes were down-regulated and 166 genes were up-regulated by at ...
Source: Toxicological Sciences - February 20, 2014 Category: Toxicology Authors: Gabehart, K., Correll, K. A., Yang, J., Collins, M. L., Loader, J. E., Leach, S., White, C. W., Dakhama, A. Tags: Research Article Source Type: research

Maintenance of Immunological Homeostasis by Indukantha Ghritha in Patients with Recurrent Upper Respiratory Tract Infections—A Pilot Study
This study was designed to scientifically validate and evaluate the immunological response mechanisms in patients with RURI. Primarily, immunological functioning of the lymphocyte subsets, Th1 and Th2 cytokines, and immunoglobulins was evaluated before and after administration of IG in patients (n = 48) and normal subjects (n = 25) for a period of 28 days. Flow cytometry revealed a significant increase in the CD3+, CD4+ T cells and CD56+ natural killer cells with a concomitant reduction of percentage of B cells during IG treatment. Increased Th1 cytokines, IL‐2 and IFN‐γ, and decreased Th2 cytokine, IL‐4, ...
Source: Phytotherapy Research - February 20, 2014 Category: Biochemistry Authors: Rajesh Radhakrishnan, Suraj K. George, Sunil Kumar, Prabha Balaram Tags: Research Article Source Type: research

Cathepsin K overexpression modifies lung development in newborn mice
Summary Cathepsin K (CatK), contributes to the development of chronic lung disease in newborn infants, but the impact of CatK for the lungs may be multifaceted. We have previously demonstrated that low level of CatK is associated with newborn lung injury and CatK deficiency aggravates lung injury in hyperoxia‐exposed newborn mice. Thus, we hypothesized that sustained/higher expression of CatK could ameliorate hyperoxia‐induced injury and restrain the development of pulmonary fibrosis. We studied the lungs of newborn wild‐type (WT) and CatK overexpressing transgenic mice (TG) that were exposed to hyperoxia or room air...
Source: Pediatric Pulmonology - February 20, 2014 Category: Respiratory Medicine Authors: Jonni Knaapi, Riku Kiviranta, Jukka Laine, Pekka Kääpä, Heikki Lukkarinen Tags: Original Article: Neonatal Lung Disease Source Type: research

Accuracy of tidal breathing measurement of floright compared to an ultrasonic flowmeter in infants
ConclusionFloRight® accurately measures time indices and may discriminate between healthy infants and those with lung disease, but demonstrates differences in tidal volume measurements. It may be better suited to monitor breathing pattern than for TBFVL measurements. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - February 20, 2014 Category: Respiratory Medicine Authors: Nicole C.M. Petrus, Cindy Thamrin, Oliver Fuchs, Urs Frey Tags: Original Article: Pulmonary Physiology Source Type: research