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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 3.

Expert consensus on image-guided radiofrequency ablation of pulmonary tumors-2015 edition.
Authors: Liu BD, Zhi XY PMID: 26101663 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The AME Special Competition 2015: 4 rounds, 27 contestants, countless lessons learned about China.
Authors: Sihoe AD PMID: 26101662 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Author response to letter to the editor "Protocolized weaning from mechanical strategy in COPD: respiratory therapists versus physician directed-who guides best?".
Authors: Kirakli C, Ediboglu O, Naz I, Cimen P, Tatar D PMID: 26101661 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Protocolized weaning from mechanical strategy in chronic obstructive pulmonary disease: respiratory therapists versus physician directed-who guides best?
Authors: Erbabacan E, González Pérez MI, Koksal GM, Esquinas AM PMID: 26101660 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Fixation of sternal fracture using absorbable plating system, three years follow-up.
We report the first case where absorbable plate has been used to fix a traumatic fracture in a 42-year-old female. After 3 years, the patient is still free of symptoms and CT scanning reveals intact sternal bone structure. PMID: 26101659 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Malignant glomus tumor in pleural cavity.
Authors: Lin F, Yang M, Pu Q, Ma L, Liu C, Mei J, Guo C, Liu L Abstract Glomus tumors, an uncommon hypervascular tumor, arise from modified smooth muscle cells of the glomus body that plays a significant role in the regulation of skin circulation. The tumors are usually located in the extremities, typically in the subungual region of the fingers. Primary glomus tumors of the chest are extremely rare, and to our knowledge, there are no cases have been described in thoracic cavity to date. We here report a case of intrathoracic glomus tumor in a 31-year-old man who presented with a persistent chest pain. Chest comput...
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Single incision thoracoscopic lobectomy through a 2.5 cm skin incision.
Authors: Yang HC, Noh D Abstract Single incision thoracoscopic surgery (SITS) involves only one intercostal space with minimal skin incision, which means it can be the most minimally invasive technique up to date. We minimized the skin incision to a length of 2.5 cm to achieve the less chest wall trauma and the more cosmesis during SITS lobectomy for benign pulmonary disease. Four patients who had bronchiectasis [left lower lobe (LLL)], congenital lobar emphysema [left upper lobe (LUL)], aspergilloma [right upper lobe (RUL)], and hamartoma (RUL) were planned to undergo 2.5 cm SITS lobectomy. There were no conversio...
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Migratory eosinophilic alveolitis caused by radiation therapy.
We report the case of a 27-year-old female with radiation pneumonitis, occurring 4 months after radiation therapy for cancer of the left breast. Clinical and radiological relapse followed withdrawal of corticosteroids. Examination of bronchoalveolar lavage (BAL) in patchy airspace consolidations revealed increased eosinophil counts. Finally, clinical and radiological signs resolved rapidly after reintroduction of corticosteroids. Eosinophilic alveolitis may be promoted by radiation therapy. In the present case report, possible mechanisms for radiation-induced eosinophilic alveolitis are also reviewed. PMID: 26101656 [...
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Beware the 'raised right hemidiaphragm' in a female patient with previous pneumothorax surgery: liver herniation through a massive endometrosis-related diaphragmatic fenestration.
Authors: Yu PS, Sihoe AD Abstract A 44-year-old non-smoking woman presented with recurrent right spontaneous pneumothorax 9 years after a right-side surgical pleurodesis via a video-assisted thoracic surgery (VATS) approach for suspected primary pneumothorax in another center. Histological examination of tissue excised during the earlier operation confirmed catamenial pneumothorax, but no further treatment was given. During the 9 years since, she had had persistent right lower chest pain and chest X-ray (CXR) had shown a "persistently elevated right diaphragm", but these had been treated as iatrogenic neuropathic p...
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Artificial neural networks for small dataset analysis.
Authors: Pasini A Abstract Artificial neural networks (ANNs) are usually considered as tools which can help to analyze cause-effect relationships in complex systems within a big-data framework. On the other hand, health sciences undergo complexity more than any other scientific discipline, and in this field large datasets are seldom available. In this situation, I show how a particular neural network tool, which is able to handle small datasets of experimental or observational data, can help in identifying the main causal factors leading to changes in some variable which summarizes the behaviour of a complex system...
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Respiratory management of the obese patient undergoing surgery.
Authors: Hodgson LE, Murphy PB, Hart N Abstract As a reflection of the increasing global incidence of obesity, there has been a corresponding rise in the proportion of obese patients undergoing major surgery. This review reports the physiological effect of these changes in body composition on the respiratory system and discusses the clinical approach required to maximize safety and minimize the risk to the patient. The changes in respiratory system compliance and lung volumes, which can adversely affect pulmonary gas exchange, combined with upper airways obstruction and sleep-disordered breathing need to be conside...
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Patients' preference of established and emerging treatment options for obstructive sleep apnoea.
CONCLUSIONS: More than 9 out of 10 of the respondents were interested in trying emerging technologies to treat OSA, most preferring CTES. Less sleepy patients were more likely to choose less invasive treatments. These findings will likely impact on future research and development of therapies for sleep-disordered breathing. PMID: 26101652 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Central sleep apnoea-a clinical review.
Authors: Muza RT Abstract Central sleep apnoea (CSA) is characterised by recurrent apnoeas during sleep with no associated respiratory effort. It mostly results from withdrawal of the wakefulness drive in sleep leaving ventilation under metabolic control. A detailed physiological understanding of the control of breathing in wakefulness and sleep is essential to the understanding of CSA. It encompasses a diverse group of conditions with differing aetiologies and pathophysiology. Likewise treatment varies according to underlying aetiology. Some of the conditions such as idiopathic (primary) CSA (ICSA) are relatively ...
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Epidemiological aspects of obstructive sleep apnea.
This article addresses OSA from an epidemiological perspective, from prevalence studies to economic aspects to co-morbidity. PMID: 26101650 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Established vascular effects of continuous positive airway pressure therapy in patients with obstructive sleep apnoea-an update.
Authors: Wons AM, Kohler M Abstract The aim of this review was to summarize the current data from randomised controlled trials (RCTs) on vascular effects of continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnoea (OSA). There is good evidence from RCTs that CPAP lowers blood pressure (BP) to a clinically significant amount. The effect seems to be dependent on the hours of nightly CPAP usage. Data from RCTs have also proven a beneficial effect of CPAP on measures of vascular function such as endothelial function and arterial stiffness. However, there is still a lack of evidence f...
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Inflammatory myofibroblastic tumour of the lung: a reactive lesion or a true neoplasm?
Authors: Panagiotopoulos N, Patrini D, Gvinianidze L, Woo WL, Borg E, Lawrence D Abstract Inflammatory myofibroblastic tumour (IMT) of the lung represents an extremely rare type of inflammatory pseudo tumor that appears most commonly in children and young individuals. There has been an ongoing controversy whether an IMT is a reactive lesion or a true neoplasm making the further management extremely challenging. Purpose of the paper is through a literature review to highlight the existence of this rare tumour along with its key features and the management options available. PMID: 26101648 [PubMed] (Source: Jour...
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Post-treatment change in Mycobacterium tuberculosis antigen-stimulated tumor necrosis factor-alpha release in patients with active tuberculosis.
CONCLUSIONS: This finding cautiously suggests that MTB Ag-stimulated TNF-α response may be a potential adjunctive marker for monitoring treatment response in active TB patients. PMID: 26101647 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The use of an online pictorial Epworth Sleepiness Scale in the assessment of age and gender specific differences in excessive daytime sleepiness.
CONCLUSIONS: The online pictorial ESS identifies gender differences in EDS and reveals increased levels of sleepiness associated with higher age. The use of modern media facilitates reaching out to the general population to raise awareness of conditions associated with EDS such as sleep apnoea. PMID: 26101646 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Kinetics of plasma microRNA-499 expression in acute myocardial infarction.
CONCLUSIONS: Cardiac-specific miRNA-499 levels were found to be linearly proportional to myocardial damage. MiRNA-499 might prove to be a new biomarker for AMI and a predictor of the risk of myocardial ischemia. PMID: 26101645 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Benefit of initial dual-therapy on stroke prevention in Chinese hypertensive patients: a real world cohort study.
CONCLUSIONS: Our study demonstrates that, for patients with uncontrolled hypertension, initial dual therapy is more effective in the prevention of stroke during the first 6 months of treatment, but not thereafter. Combination antihypertensive therapy may be a beneficial initial strategy for early stroke prevention. PMID: 26101644 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Clinical features and mutation status of EGFR, KRAS, BRAF, EML4-ALK and ROS1 between surgical resection samples and non surgical resection samples in lung cancer.
CONCLUSIONS: Both surgical resection samples and biopsy samples could be used to perform the testing the driver gene mutation. PMID: 26101643 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Screening for pectus excavatum among primary students and establishment of a pectus excavatum screening program in Dongguan, China.
CONCLUSIONS: The screening for PEx was successfully performed among pupils who were already in school in 2012 or newly enrolled in 2013 from 422 primary schools in Dongguan, Guangdong Province. Statistical analysis showed that the incidence of PEx differed between male and female pupils. A stable effective PEx screening program was established, which will provide personal and technical supports for the early diagnosis and treatment of this condition. PMID: 26101642 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

One-stage hybrid procedure without sternotomy for treating thoracic aortic pathologies that involve distal aortic arch: a single-center preliminary study.
CONCLUSIONS: Initial results suggest that the one-stage hybrid procedure is a suitable therapeutic option for thoracic aortic pathologies that involve distal aortic arch. However, this procedure is not recommended for type-B aortic dissection, in which a tear is located in the greater curvature or near the left subclavian artery (LSA), because of the high possibility of endoleak occurrence. PMID: 26101641 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Expression of paired basic amino acid-cleaving enzyme 4 (PACE4) correlated with prognosis in non-small cell lung cancer (NSCLC) patients.
CONCLUSIONS: Our results suggest that positive expression of PACE4 is an independent factor for NSCLC patients and it might serve as a potential prognostic biomarker for patients with NSCLC. PMID: 26101640 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Clinical characteristics of idiopathic pulmonary fibrosis patients with gender, age, and physiology staging at Okinawa Chubu Hospital.
CONCLUSIONS: In our cohort, GAP staging was useful for evaluating IPF severity. Stage III patients might had more pulmonary hypertension and progressive dyspnea. Multicenter analyses are warranted to confirm these findings. PMID: 26101639 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Thoracoscopic double sleeve lobectomy in 13 patients: a series report from multi-centers.
CONCLUSIONS: Thoracoscopic double sleeve lobectomy is a technically challenging, but feasible procedure for NSCLC patients and it should be restricted to skilled VATS surgeons. PMID: 26101638 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Prognostic role of p53 and Ki-67 immunohistochemical expression in patients with surgically resected lung adenocarcinoma: a retrospective study.
CONCLUSIONS: IHC expression of Ki-67 in lung adenocarcinoma tissue shows stronger association with poor tumor differentiation, and negatively affects patients' survival in advanced-stage lung cancer; however, the role of p53 on patient outcome needs further study. PMID: 26101637 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Initial thrombolysis treatment compared with anticoagulation for acute intermediate-risk pulmonary embolism: a meta-analysis.
CONCLUSIONS: Thrombolytic treatment for intermediate-risk PE patients, if not contraindicated, could reduce clinical deterioration and recurrence of PE, and trends towards a decrease in all-cause, 30-day mortality. Despite thrombolytic treatment having an increased total bleeding risk, there was no difference in the incidence of major bleeding events, compared with patients receiving anticoagulation treatment. PMID: 26101636 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Meta-analysis of the diagnostic yield and safety of electromagnetic navigation bronchoscopy for lung nodules.
CONCLUSIONS: ENB is an effective and safe procedure in diagnosing peripheral lung lesions. PMID: 26101635 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Low bone mineral density is associated with increased arterial stiffness in participants of a health records based study.
CONCLUSIONS: Independent of confounding factors, low BMD is associated with the functional marker of subclinical atherosclerosis (increased baPWV), but not with structural markers (ABI, CIMT, eGFR or microalbuminuria) among healthy females and males. PMID: 26101634 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Effect of initial antihypertensive combination therapy on primary stroke prevention.
Authors: Noubiap JJ PMID: 26101633 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Less invasive left ventricular assist device implantation-a match changer!
Authors: Reineke DC, Carrel TP PMID: 26101632 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The Three A's in Asthma - Airway Smooth Muscle, Airway Remodeling & Angiogenesis.
The Three A's in Asthma - Airway Smooth Muscle, Airway Remodeling & Angiogenesis. Open Respir Med J. 2015;9:70-80 Authors: Keglowich LF, Borger P Abstract Asthma affects more than 300 million people worldwide and its prevalence is still rising. Acute asthma attacks are characterized by severe symptoms such as breathlessness, wheezing, tightness of the chest, and coughing, which may lead to hospitalization or death. Besides the acute symptoms, asthma is characterized by persistent airway inflammation and airway wall remodeling. The term airway wall remodeling summarizes the structural changes in the...
Source: Open Respiratory Medicine Journal - June 26, 2015 Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research

The role of serological testing in idiopathic interstitial pneumonia: a rheumatologist perspective
This article will highlight the importance of serological testing in patients with IIPs and the role of the rheumatologist in evaluating these patients. (Source: Current Respiratory Care Reports)
Source: Current Respiratory Care Reports - June 26, 2015 Category: Respiratory Medicine Source Type: research

News
(Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - June 26, 2015 Category: Respiratory Medicine Source Type: research

Editorial Board
(Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - June 26, 2015 Category: Respiratory Medicine Source Type: research

What's new in thymic neoplasms
Purpose of review: The past 5 years have been marked with major developments in the field of thymic malignancies. Recent findings: A lack of progress over decades has been transformed into dramatic advancements over the past 5 years through the creation of the International Thymic Malignancy Interest Group (ITMIG). ITMIG has brought together an engaged worldwide community interested in this field. An unprecedented global database has been developed and is being actively analyzed. Standard definitions have been established to allow collaboration; the histologic classification has been revised and the first formal stage clas...
Source: Current Opinion in Pulmonary Medicine - June 26, 2015 Category: Respiratory Medicine Tags: NEOPLASMS OF THE LUNG: Edited by Alan Fein and Anne-Marie C. Dingemans Source Type: research

The Solitary Pulmonary Nodule
Due to the high etiological diversity and the potential for malignancy, pulmonary nodules represent a clinical challenge, becoming increasingly frequent as the number of CT examinations rises. The topic gains even more importance as clear evidence for the effectiveness of CT screening was provided by the National Lung Screening Trial (NLST). Yet, the results were tempered by the high false-positive rate and the requirement of performing further diagnostic procedures. The management of those detected solitary pulmonary nodules is currently based on the individuals' risk of developing lung cancer, the pulmonary nodule charac...
Source: Respiration - June 26, 2015 Category: Respiratory Medicine Source Type: research

Bronchoscopic Coil Treatment for Patients with Severe Emphysema: A Meta-Analysis
Conclusions: Bronchoscopic coil treatment improves pulmonary function, 6MWD, and quality of life in patients with severe emphysema up to 1 year after treatment, independent of the distribution of the disease.Respiration (Source: Respiration)
Source: Respiration - June 26, 2015 Category: Respiratory Medicine Source Type: research

Grey scale texture analysis of endobronchial ultrasound mini probe images for prediction of benign or malignant aetiology
ConclusionsGreyscale texture analysis of EBUS‐MP images can help establish aetiology with a high NPV for malignancy. (Source: Respirology)
Source: Respirology - June 26, 2015 Category: Respiratory Medicine Authors: Phan Nguyen, Farzad Bashirzadeh, Justin Hundloe, Olivier Salvado, Nicholas Dowson, Robert Ware, Ian Brent Masters, Aravind Ravi Kumar, David Fielding Tags: Original Article Source Type: research

Understanding Middle East respiratory syndrome
Abstract: Middle East respiratory syndrome is an infection caused by a novel coronavirus. The primary source of the virus is infected camels in several countries in the Arabian peninsula. The infection is acquired by coming into contact with infected animals, animal products, or with patients who have the syndrome. Mortality for this syndrome is 30% to 40%, and treatment is supportive because no antiviral therapy exists. (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - June 26, 2015 Category: Primary Care Tags: Special Topics in Infectious Diseases Source Type: research

Understanding Guillain-Barré syndrome
Abstract: Guillain-Barré syndrome (GBS) is a rapidly progressive peripheral neuropathy that most commonly presents with ascending symmetrical weakness and diminished or absent deep tendon reflexes. Because weakness may affect the diaphragm and cause respiratory distress, 10% to 30% of patients require mechanical ventilation. Symptoms progress and peak about 4 weeks after onset. Patients generally require hospitalization for respiratory and cardiac monitoring, as well as supportive care and treatment. The treatments of choice are IV immunoglobulin and plasmapheresis. Even after treatment, as many as 20% of patients have pe...
Source: Journal of the American Academy of Physician Assistants - June 26, 2015 Category: Primary Care Tags: CME: Neurology Source Type: research