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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 3.

Portrayal of tobacco in Mongolian language YouTube videos: policy gaps
Conclusions Given the popularity of Mongolian YouTube videos that promote smoking, policy changes are urgently required to control this medium, and more effectively protect youth and young adults from insidious tobacco marketing. (Source: Tobacco Control)
Source: Tobacco Control - June 22, 2016 Category: Respiratory Medicine Authors: Tsai, F.-J., Sainbayar, B. Tags: Research paper Source Type: research

Investment incentives and the implementation of the Framework Convention on Tobacco Control: evidence from Zambia
Conclusions Much of the struggle Zambia has experienced in implementing the FCTC can be attributed to misalignments between the economic and health sectors. Zambia's development agenda seeks to bolster agricultural processing and manufacturing. Tobacco control proponents must recognise and work within this context in order to foster productive strategies with those working on tobacco supply issues. These findings are broadly applicable to the global context. It is important that the Ministry of Health monitors the tobacco policy of and engages with these sectors to find ways of harmonising FCTC implementation. (Source: Tobacco Control)
Source: Tobacco Control - June 22, 2016 Category: Respiratory Medicine Authors: Lencucha, R., Drope, J., Labonte, R., Zulu, R., Goma, F. Tags: Research paper Source Type: research

When a ban really is not a ban: internet loopholes and Djarum flavoured cigarettes in the USA
This study describes: (A) online consumer interest4 in, and (B) promotion and availability of Djarum cigarettes, and their cigar replacements, before and after the USA banned flavoured cigarettes in 2009. Methods Google searches originating in the USA including ‘Djarum’ in combination with ‘cigarette/s’ versus ‘Djarum’ in combination with ‘cigar/s’ (eg, ‘Djarum cigarettes’ would be pooled in the cigarette trend) were monitored (google.com/trends), then regressed on time (eg, 2008–2014). The top 50 Google search results between 29 August 2013 and 28 November ...
Source: Tobacco Control - June 22, 2016 Category: Respiratory Medicine Authors: Allem, J.-P., Ayers, J. W., Althouse, B. M., Williams, R. Tags: Research letter Source Type: research

Meta‐analysis and Systematic Review of Procalcitonin‐Guided Treatment in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Conclusion: Results from this meta‐analysis suggest PCT‐guided treatment can safely reduced antibiotic overuse in patients with AECOPD. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 22, 2016 Category: Respiratory Medicine Authors: Qiyuan Pang, Changyang Lin Tags: Review Article Source Type: research

Oki Stent application in different indications: Six cases
Conclusions: Oki stents can safely be used for many clinical conditions. Patients benefit greatly from stenting, however, two of our cases died due to infection, and one case died due to malignancy. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 22, 2016 Category: Respiratory Medicine Authors: Mehmet Akif Özgül, Erdoğan Çetinkaya, Mustafa Çörtük, Elif Tanrıverdi O, Binnaz Zeynep Yıldırım, Merih Balci Kalamanoğlu, Adamu Issaka, Güler Özgül Tags: Original Article Source Type: research

Association of eNOS, ACE gene polymorphisms and plasma nitric oxide with risk of Non‐small cell lung cancer in South India
Conclusions: We report for the first time that polymorphisms in the eNOS ‘A/A'(homozygous mutant) and ACE ‘I/D' genotypes might contribute to the increased risk of NSCLC in the South Indian population. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 22, 2016 Category: Respiratory Medicine Authors: Vidyullatha Peddireddy, Siva Prasad Badabagni, Sandhya Devi Gundimeda, Hema Prasad Mundluru Tags: Original Article Source Type: research

Effect of perioperative systemic steroid treatment on patients with obstructive lung disease undergoing elective abdominal surgery
Conclusion: In our retrospective study we showed that those treated with steroids had better outcomes. However, future prospective and randomized controlled trials are needed. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 22, 2016 Category: Respiratory Medicine Authors: Hyun Woo Lee, Jung Kyu Lee, Sohee Oh, Deog Kyeom Kim, Hee Soon Chung, Eun Young Heo Tags: Original Article Source Type: research

Response of exhaled nitric oxide to inhaled corticosteroids in patients with stable COPD: A systematic review and meta‐analysis
Conclusion Our findings indicate that FeNO levels significantly decreased with corticosteroid treatment in ex‐smokers with COPD. Additional studies are required to evaluate whether concurrent smoking has significant effect on FeNO response to inhaled corticosteroids. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 22, 2016 Category: Respiratory Medicine Authors: Chor‐Shen Lim, Fauzi Abdul Rani, Lan‐Eng Tan Tags: Original Article Source Type: research

Biallelic Mutations in DNM1L are Associated with a Slowly Progressive Infantile Encephalopathy
In conclusion, we described a recessive disease caused by DNM1L mutations, with a clinical phenotype resembling mitochondrial disorders but without any biochemical features typical of these syndromes (lactic acidosis, respiratory chain complex deficiency) or indicating a peroxisomal disorder. This article is protected by copyright. All rights reserved (Source: Human Mutation)
Source: Human Mutation - June 22, 2016 Category: Genetics & Stem Cells Authors: Alessia Nasca, Andrea Legati, Enrico Baruffini, Cecilia Nolli, Isabella Moroni, Anna Ardissone, Paola Goffrini, Daniele Ghezzi Tags: Brief Report Source Type: research

IJERPH, Vol. 13, Pages 621: Coarse Fraction Particle Matter and Exhaled Nitric Oxide in Non-Asthmatic Children
Coarse particle matter, PMcoarse, is associated with increased respiratory morbidity and mortality. The aim of this study was to investigate the association between short-term changes in PMcoarse and sub-clininal airway inflammation in children. Healthy children aged 11 years from two northern Swedish elementary schools underwent fraction of exhaled nitrogen oxide (FENO) measurements to determine levels of airway inflammation twice weekly during the study period from 11 April–6 June 2011. Daily exposure to PMcoarse, PM2.5, NO2, NOx, NO and O3 and birch pollen was estimated. Multiple linear regression was used. Personal c...
Source: International Journal of Environmental Research and Public Health - June 22, 2016 Category: Environmental Health Authors: Hanne CarlsenPeter BomanBodil BjörAnna-Carin OlinBertil Forsberg Tags: Article Source Type: research

Human metapneumovirus uses endocytosis pathway for host cell entry
In this study, we focused on hMPV cell entry using two kinds of cell lines (Vero E6 and LLC-MK2), which are most commonly used for isolating and propagating for hMPV, and we used fluorescent dyes to label the virus particles and monitored how they enter the host cell in real time. We found that endocytosis was the predominant pathway by which hMPV entered host cells. When the virus particles were traced inside host cells, we found that a low intracellular pH was needed for intracellular fusion in LLC-MK2 cells. (Source: Molecular and Cellular Probes)
Source: Molecular and Cellular Probes - June 22, 2016 Category: Molecular Biology Source Type: research

Clinical characterization of influenza A and human respiratory syncytial virus among patients with influenza like illness
ConclusionH1N1and RSV were co‐circulated and have common clinical symptoms particularly in lower age group. Therefore, laboratory confirmation is necessary for further disease prognosis. Age was an important risk factor that affects the positivity of influenza A, H1N1 and RSV. Different clinical manifestation of H1N1 and RSV will be helpful for early and accurate diagnosis. This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)
Source: Journal of Medical Virology - June 22, 2016 Category: Virology Authors: Swati Saxena, Dharamveer Singh, Amreen Zia, Jyoti Umrao, Naveen Srivastava, Ankita Pandey, Sushma Singh, Piyali Bhattacharya, Reema Kumari, Ramawadh Kushwaha, T. N. Dhole Tags: Research Article Source Type: research

Psychogenic non-epileptic seizures in the post-anesthesia recovery unit
Discussion Psychogenic non-epileptic seizures mimic shivering, and should be considered early in the differential diagnosis of postoperative shaking, as they may be more likely than epilepsy in this setting. Pseudoseizure patterns include asynchronous convulsive episodes lasting more than 90s, forced eye closure with resistance to opening, and retained pupillary responses. Autonomic manifestations such as tachycardia, cyanosis and incontinence are usually absent. A psychiatric background is common. Knowledge and correct diagnosis of pseudoseizures is of great importance for anesthesiologists to prevent morbidity and iatrog...
Source: Brazilian Journal of Anesthesiology - June 22, 2016 Category: Anesthesiology Source Type: research

Atopy patch test with house dust mite in Chinese patients with atopic dermatitis
ConclusionThis study identified house dust mite induced cutaneous hypersensitivity in Chinese patients with AD by APT, especially in air‐exposed distribution patterns or adolescent and adult patients. Both intrinsic and extrinsic AD patients showed positive APT reactions to house dust mite. (Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - June 22, 2016 Category: Dermatology Authors: X. Dou, J. Kim, C.Y. Ni, Y. Shao, J. Zhang Tags: Original Article Source Type: research

Children with Down syndrome: Clinical course and mortality‐associated factors in a French medical paediatric intensive care unit
ConclusionsThe mortality rate in critically ill DS children admitted for medical reasons is high and is predominantly associated with respiratory conditions. (Source: Journal of Paediatrics and Child Health)
Source: Journal of Paediatrics and Child Health - June 22, 2016 Category: Pediatrics Authors: Christelle Joffre, Fabrice Lesage, Olivier Bustarret, Philippe Hubert, Mehdi Oualha Tags: Original Article Source Type: research

Understanding the role of the microbiome in COPD: Principles, Challenges and Future Directions
In the past several years, advances in sequencing platforms and bioinformatics have transformed our understanding of the relationship between microbial ecology and human health. Both the normal and diseased lung are host to hundreds of bacterial genera, blurring the lines between “colonization” and “infection”. However whereas in health the respiratory microbiome is determined primarily by the dynamic balance of immigration and elimination, in chronic disease conditions become much more favorable for the reproduction of resident bacteria. (Source: Translational Research)
Source: Translational Research - June 22, 2016 Category: Research Authors: Yvonne J. Huang, John R. Erb-Downward, Robert Dickson, Jeffrey L. Curtis, Gary B. Huffnagle, MeiLan K. Han Source Type: research

Pulmonary hypertension specific treatment in infants with bronchopulmonary dysplasia
ConclusionTreatment of BPD complicated by PH with PH‐specific medications, mainly sildenafil, is associated with improvement in both clinical and hemodynamic parameters and a low mortality rate. Pediatr Pulmonol. 2016; 9999:1–7. © 2016 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - June 22, 2016 Category: Respiratory Medicine Authors: Gili Kadmon, Ofer Schiller, Tamir Dagan, Elchanan Bruckheimer, Einat Birk, Tommy Schonfeld Tags: Original Article Source Type: research

Increased dead space in face mask continuous positive airway pressure in neonates
ConclusionsOur study indicates that face mask CPAP leads to an increase in dead space and a decrease in ventilation efficiency under certain circumstances. Pediatr Pulmonol. 2016; 9999:XX–XX. © 2016 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - June 22, 2016 Category: Respiratory Medicine Authors: Kenji Hishikawa, Hideshi Fujinaga, Yushi Ito Tags: Original Article Source Type: research

An electronic nose may sniff out amyotrophic lateral sclerosis
Publication date: Available online 22 June 2016 Source:Respiratory Physiology & Neurobiology Author(s): Silvano Dragonieri, Vitaliano N Quaranta, Pierluigi Carratu, Teresa Ranieri, Lorenzo Marra, Giuseppina D’Alba, Onofrio Resta Amyothrophic lateral Sclerosis (ALS) is a neurodegenerative disease characterized by a progressive degeneration of the cortical and spinal motor neuron. Exhaled molecular profiles that have potential in the diagnosis of several respiratory and systemic diseases can be obtained by analyzing human breath with an electronic nose. We hypothesized that exhaled molecular profiling may ...
Source: Respiratory Physiology and Neurobiology - June 22, 2016 Category: Respiratory Medicine Source Type: research

PM2.5 collected in China cause inflammatory and oxidative stress responses in macrophages through the multiple pathways
In this study, we investigated the toxicological properties of particulate matter ≤ 2.5 mm (PM2.5) collected in an urban area in China (Shenyang), focusing on inflammation and oxidative stress tightly linked to respiratory diseases. Exposure to PM2.5 significantly increased the expression levels of inflammatory (interleukin-1β and cyclooxygenase-2) and oxidative stress (heme oxygenase1) genes in the mouse macrophages. PM2.5-caused inflammatory response was strongly suppressed by endotoxin neutralizer (polymyxin B) and knock-out of toll-like receptor 4, while oxidative stress was not. On the other hand, an antioxidant (N...
Source: Environmental Toxicology and Pharmacology - June 22, 2016 Category: Environmental Health Source Type: research

Improving Delivery Accuracy of Stereotactic Body Radiotherapy to a Moving Tumor Using Simplified Volumetric Modulated Arc Therapy
Conclusion We developed a DrMAT technique for SBRT that produces plans of a quality similar to that achieved with VMAT but with better delivery accuracy. This technique is well-suited for small tumors with motion uncertainty. (Source: PLoS One)
Source: PLoS One - June 22, 2016 Category: Biomedical Science Authors: Young Eun Ko Source Type: research

Specific IgE and IgG measured by the MeDALL allergen-chip depend on allergen and route of exposure - the EGEA study
Inhalant and oral routes of exposure induce different patterns of sensitization. Oral route may preferentially induce IgG responses whereas respiratory route is important for IgE sensitization. A geographical pattern of IgE response to pollen exposure exists in France, depending on regional pollen exposure. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - June 22, 2016 Category: Allergy & Immunology Authors: Valérie Siroux, Christian Lupinek, Yvonne Resch, Mirela Curin, Jocelyne Just, Thomas Keil, Renata Kiss, Karin Lodrup Carlsen, Erik Melén, Rachel Nadif, Isabelle Pin, Ingebjørg Skrindo, Susanne Vrtala, Magnus Wickman, Josep Maria Anto, Rudolf Valenta, J Source Type: research

Critical roles of adenosine A2A receptor in regulating the balance of Treg/Th17 cells in allergic asthma
ConclusionA2AR could regulate the balance of Treg/Th17 cells in asthma. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 22, 2016 Category: Respiratory Medicine Authors: Linlin Wang, Huanying Wan, Wei Tang, Yingmeng Ni, Xiaoxia Hou, Lina Pan, Yuanlin Song, Guochao Shi Tags: Original Article Source Type: research

Association between fractional exhaled nitric oxide (FeNO) cutoff values (25 ppb) and risk factors of cough
ConclusionThe cutoff values of FeNO (≥25 ppb or <25 ppb) are useful for etiological detection of cough with high sensitivity. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 22, 2016 Category: Respiratory Medicine Authors: Ling Qian, Shiying Pan, Jingdong Shi, Yong Du, Qihui Huang, Zhijun Jie Tags: Original Article Source Type: research

Effect of time and body position on ventilation in premature infants.
CONCLUSION: Regional ventilation distribution is influenced by time independent of changes due to body position. Differences exist between infants on ventilatory support compared with those who are spontaneously breathing. Infants receiving ventilatory support have a physiological peak in lung function after 2 h which remains above baseline at 4 h. A change in body position facilitates an improvement in lung function in infants on ventilatory support.Pediatric Research (2016); doi:10.1038/pr.2016.116. PMID: 27331352 [PubMed - as supplied by publisher] (Source: Pediatric Research)
Source: Pediatric Research - June 22, 2016 Category: Pediatrics Authors: Hough J, Trojman A, Schibler A Tags: Pediatr Res Source Type: research

The 6-minute Walk Test as a COPD Stratification Tool: Insights From the COPD Biomarker Qualification Consortium.
CONCLUSIONS: The 6MWD may help stratify COPD patients for clinical trials and interventions aimed at modifying exacerbations, hospitalizations or death. PMID: 27332504 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - June 22, 2016 Category: Respiratory Medicine Authors: Celli B, Tetzlaff K, Criner G, Polkey MI, Sciurba F, Casaburi R, Tal-Singer R, Kawata A, Merrill D, Rennard S, COPD Biomarker Qualification Consortium Tags: Am J Respir Crit Care Med Source Type: research

Effect of Nintedanib in Subgroups of Idiopathic Pulmonary Fibrosis by Diagnostic Criteria.
CONCLUSION: Patients with IPF diagnosed in clinical practice who have possible UIP with traction bronchiectasis on HRCT and have not undergone surgical lung biopsy have disease that progresses in a similar way, and responds similarly to nintedanib, as patients with honeycombing on HRCT and/or confirmation of UIP by biopsy. Clinical trial registration available at www.clinicaltrials.gov, IDs NCT01335464 and NCT01335477. PMID: 27331880 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - June 22, 2016 Category: Respiratory Medicine Authors: Raghu G, Wells AU, Nicholson AG, Richeldi L, Flaherty KR, Le Maulf F, Stowasser S, Schlenker-Herceg R, Hansell DM Tags: Am J Respir Crit Care Med Source Type: research

Mortality due to Respiratory Syncytial Virus: Burden and Risk Factors.
FM, Libster R, Karron RA, Bergel E, Polack FP Abstract RATIONALE: Respiratory syncytial virus (RSV) is the most frequent cause of hospitalization and an important cause of death in infants in the developing world. The relative contribution of social, biological, and clinical risk factors to RSV mortality in low-income regions is unclear. OBJECTIVES: To determine the burden and risk factors for mortality due to RSV in a low-income population of 84,840 infants. METHODS: A prospective, population-based, cross-sectional, multicenter study conducted between 2011 and 2013. Hospitalizations and deaths due to sever...
Source: American Journal of Respiratory and Critical Care Medicine - June 22, 2016 Category: Respiratory Medicine Authors: Geoghegan S, Erviti A, Caballero MT, Vallone F, Zanone SM, Losada JV, Bianchi A, Acosta PL, Talarico LB, Ferretti A, Grimaldi LA, Sancilio A, Dueñas K, Sastre G, Rodriguez A, Ferrero F, Barboza E, Gago GF, Nocito C, Flamenco E, Perez AR, Rebec B, Ferolla Tags: Am J Respir Crit Care Med Source Type: research

Forensic Features of Lethal Late-Presenting Diaphragmatic Hernias.
Abstract Diaphragmatic defects are a relatively common and benign finding in adults which may be congenital or secondarily acquired. The case files at Forensic Sciences South Australia were reviewed over a 10-year period from July 2005 to June 2015 for all adult (>17 years) cases in which diaphragmatic hernias were identified at postmortem examination that had either caused or contributed to death. Five cases were found: age range 49-90 years (average 67.2 years); male:female ratio 2:3. Herniated organs included the stomach (N = 3), small (N = 3) and large intestines (N = 2). Mechanisms of death involved lung co...
Source: Journal of Forensic Sciences - June 22, 2016 Category: Forensic Medicine Authors: Thompson M, Wills S, Byard RW Tags: J Forensic Sci Source Type: research

Direct Real-Time Quantification of Mitochondrial Oxidative Phosphorylation Efficiency in Permeabilized Skeletal Muscle Myofibers.
Abstract Oxidative phosphorylation (OXPHOS) efficiency, defined as the ATP:O ratio, is a critical feature of mitochondrial function that has been implicated in health, aging and disease. To date however, the methods to measure ATP:O have primarily relied on indirect approaches or entail parallel rather than simultaneous determination of ATP synthesis and O2 consumption rates. The purpose of this project was to develop and validate an approach to determine ATP:O ratio in permeabilized fiber bundles (PmFBs) from simultaneous measures of ATP synthesis (JATP) and O2 consumption (JO2) rates in real-time using a custom-d...
Source: Am J Physiol Cell Ph... - June 22, 2016 Category: Cytology Authors: Lark DS, Torres MJ, Lin CT, Ryan TE, Anderson EJ, Neufer PD Tags: Am J Physiol Cell Physiol Source Type: research

The Six-Minute Stepper Test: Solvitur ambulando
Respiration (Source: Respiration)
Source: Respiration - June 21, 2016 Category: Respiratory Medicine Source Type: research

Functional Characterization of Patients with Chronic Thromboembolic Disease
This study aimed to analyze the exercise capacity and limiting factors in CTED. Methods: We compared right heart catheterization and cardiopulmonary exercise test results of patients with CTED [mean pulmonary artery pressure (mPAP) at rest (Source: Respiration)
Source: Respiration - June 21, 2016 Category: Respiratory Medicine Source Type: research

Painful Oral Ulcers With Lymphadenopathy and Respiratory Symptoms: Challenge
No abstract available (Source: The American Journal of Dermatopathology)
Source: The American Journal of Dermatopathology - June 21, 2016 Category: Pathology Tags: Clinical Pathologic Challenge Source Type: research

Painful Oral Ulcers With Lymphadenopathy and Respiratory Symptoms
No abstract available (Source: The American Journal of Dermatopathology)
Source: The American Journal of Dermatopathology - June 21, 2016 Category: Pathology Tags: Clinical Pathologic Challenge Answer Source Type: research

Underestimation of homeless clients.
Conclusions: Many smokers using homeless services want to quit and are actively trying to reduce and quit smoking. Smoking-cessation assistance that meets the needs of people experiencing homelessness is clearly warranted.So what?: Homeless services should develop, and include in their smoking policy and intake processes, a practice of routinely assessing tobacco use, offering brief interventions and referral to appropriately tailored services. PMID: 27321708 [PubMed - as supplied by publisher] (Source: Health Promotion Journal of Australia)
Source: Health Promotion Journal of Australia - June 21, 2016 Category: Global & Universal Tags: Health Promot J Austr Source Type: research

Effect of Mechanical Ventilation Mode Type on Intra- and Postoperative Blood Loss in Patients Undergoing Posterior Lumbar Interbody Fusion Surgery A Randomized Controlled Trial
Conclusion Intraoperative PCV decreased intraoperative surgical bleeding in patients undergoing PLIF, which may be related to lower intraoperative peak inspiratory pressure. (Source: Anesthesiology)
Source: Anesthesiology - June 21, 2016 Category: Anesthesiology Source Type: research

Continuous Positive Airway Pressure Mitigates Opioid-induced Worsening of Sleep-disordered Breathing Early after Bariatric Surgery
Conclusions This pharmacophysiologic interaction trial shows that supervised CPAP treatment early after surgery improves SDB and ameliorates the respiratory-depressant effects of opioids without undue hemodynamic effects. (Source: Anesthesiology)
Source: Anesthesiology - June 21, 2016 Category: Anesthesiology Source Type: research

Control of Respiratory Drive and Effort in Extracorporeal Membrane Oxygenation Patients Recovering from Severe Acute Respiratory Distress Syndrome
Conclusions In patients recovering from ARDS undergoing ECMO, the amount of carbon dioxide removed by the artificial lung may influence spontaneous breathing. The effects of carbon dioxide removal on spontaneous breathing during the earlier acute phases of ARDS remain to be elucidated. (Source: Anesthesiology)
Source: Anesthesiology - June 21, 2016 Category: Anesthesiology Source Type: research

Efficacy and safety of SQ house dust mite (HDM) SLIT-tablet treatment of HDM allergic asthma.
Authors: Canonica GW, Virchow JC, Zieglmayer P, Ljørring C, Smith IM, Mosbech H Abstract INTRODUCTION: In the treatment of house dust mite (HDM) respiratory allergic disease, allergy immunotherapy constitutes an add-on treatment option targeting the underlying immunological mechanisms of allergic disease. However, for the treatment of HDM allergic asthma, the use of subcutaneous allergy immunotherapy (SCIT) has been limited by the risk of systemic adverse events. Thus, sublingually administered allergy immunotherapy (SLIT) has been investigated as a treatment option with an improved tolerability profile that allow...
Source: Expert Review of Clinical Immunology - June 21, 2016 Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research