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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 3.

Improved repeatability of nasal potential difference with a larger surface catheter
To increase the power of nasal potential difference (NPD) as a biomarker of CFTR function, improvement of its repeatability is needed. We evaluated the improvement in repeatability resulting from measuring NPD (1) over a larger surface area and (2) at a fixed location. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - October 28, 2014 Category: Respiratory Medicine Authors: François Vermeulen, Marijke Proesmans, Mieke Boon, Kris De Boeck Tags: Original Article Source Type: research

Mechanical ventilation in critically ill cancer patients
One of the main reasons cancer patients are admitted to an intensive care unit (ICU) is acute respiratory failure (ARF) requiring mechanical ventilation. ARF with the need for ventilatory support is usually associated with high mortality and morbidity. In a recent study, researchers reported that the ICU and hospital mortality rates of ARF in cancer patients on a ventilator is about 54%, and 67%, respectively.1 The National Cancer Institute of Mexico has a medical-surgical ICU with six beds that are exclusively for oncology patients. (Source: Heart and Lung)
Source: Heart and Lung - October 28, 2014 Category: Intensive Care Authors: Silvio A. Ñamendys-Silva, Yves D. Jarquin-Badiola, Francisco J. García-Guillén, Julia Texcocano-Becerra, Ricardo Cázares-Mejía, Angel Herrera-Gómez Tags: Letter to the Editor Source Type: research

Impact of target volume segmentation accuracy and variability on treatment planning for 4D-CT-based non-small cell lung cancer radiotherapy.
Conclusions. Significant target volume segmentation and dosimetric variability exists in IMRT treatment planning amongst experts in the presence of a reference standard for 4D-CT-based lung cancer radiotherapy. Future work is needed to mitigate this uncertainty and ensure highly accurate and effective radiotherapy for lung cancer patients. PMID: 25350526 [PubMed - as supplied by publisher] (Source: Acta Oncologica)
Source: Acta Oncologica - October 28, 2014 Category: Cancer & Oncology Authors: Martin S, Johnson C, Brophy M, Palma DA, Barron JL, Beauchemin SS, Louie AV, Yu E, Yaremko B, Ahmad B, Rodrigues GB, Gaede S Tags: Acta Oncol Source Type: research

Extended Chest Wall Resection and Reconstruction in the Setting of Lung Cancer
Resection of the chest wall for lung cancer by definition indicates locally advanced disease. Complete en bloc removal of the tumor and thorough surgical staging is paramount for offering the best treatment and increasing the chances of prolonged survival. Thorough knowledge of all the reconstructive techniques available is critical to allow appropriate operative planning. A multidisciplinary approach including involvement of plastic and spinal surgery expertise should be considered when planning a large resection. Repairs should give structural stability while maintaining functional capacity of the thorax. Respiratory and...
Source: Thoracic Surgery Clinics - October 27, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Daine T. Bennett, Michael J. Weyant Source Type: research

Evaluation of PCR‐Reverse blot hybridization assay for the differentiation and identification of Mycobacterium species in liquid cultures
ConclusionsPCR‐REBA assay showed rapid, highly sensitive, and specific results for the identification of MTB and NTM, and discriminated between NTM species from mycobacterial liquid cultures. Significance and Impact of the StudyEven though the use of molecular diagnostic technologies is more expensive than the use of conventional methods, the clinical and economic benefit of saving time in regard to expenses remains to be elucidated. Therefore, the PCR‐REBA assay may provide the essential information to accelerate therapeutic decisions for appropriate antibiotic treatments in the acute phase of mycobacterial diseases.T...
Source: Journal of Applied Microbiology - October 27, 2014 Category: Microbiology Authors: Hye‐young Wang, Hyungjung Kim, Sunghyun Kim, Hyeeun Bang, Do‐kyoon Kim, Hyeyoung Lee Tags: Original Article Source Type: research

POLASTMA - the Polish National Programme of Early Diagnosis and Therapy of Asthma.
Abstract Asthma represents a growing health, social, and economic issue as it affects a considerable part of the population, adversely affecting patients' quality of life, while its chronic character and severity of symptoms impair family life. It has been estimated that 12% of the population of Poland (4.5 million) suffer from asthma and 16% report wheezes (5.7 million). In order to improve asthma care and patient outcomes, evidence-based recommendations must not only be developed, but also disseminated and implemented at a national and local level, which is key for integration into clinical practice. For these re...
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Kuna P, Kupczyk M, Kupryś-Lipińska I Tags: Pneumonol Alergol Pol Source Type: research

[Chronic obstructive pulmonary disease and cardiovascular diseases - 'cardiopulmonary continuum'].
Abstract Chronic obstructive pulmonary disease (COPD) is characterised by persistent airflow limitation and extrapulmonary comorbidities, which contribute to the overall severity. Some risk factors, with tobacco smoking as the most serious one, lead to a chronic, systemic inflammation that plays the main role in the pathogenesis of COPD and comorbidities, including cardiovascular diseases (CVD). The course of COPD is diverse; it depends on pathologies in the respiratory system and on other organ dysfunctions. CVDs are the most commonly recognised comorbidities in COPD patients. The severity and natural course of CO...
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Batura-Gabryel H, Grabicki M Tags: Pneumonol Alergol Pol Source Type: research

Severe congestive heart failure as the main symptom of eosinophilic granulomatosis and polyangiitis (Churg-Strauss syndrome).
We present a patient with asthma and eosinophilia in whom EGPA was diagnosed in the course of acute recurrent substernal chest pain, with subsequent signs of cardiac insufficiency. PMID: 25339570 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Załęska J, Wiatr E, Zych J, Szopiński J, Oniszh K, Kober J, Piotrowska-Kownacka D, Roszkowski-Śliż K Tags: Pneumonol Alergol Pol Source Type: research

[Obliterative bronchiolitis due to inhalation of toxic gases and fumes - case report].
We present a young chemist exposed to inhalation of toxic gases and fumes due to lack of usage of any personal protective equipment. He was referred to our lung disease department because of shortness of breath on exertion and irreversible airflow limitation. Definitive diagnosis of obliterative bronchiolitis was established by histological examination of specimen from open lung biopsy. PMID: 25339569 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Winek J, Zych J, Langfort R, Roszkowski-Śliż K Tags: Pneumonol Alergol Pol Source Type: research

[Acute interstitial pneumonia in patient with rheumatoid arthritis treated with leflunomide].
We present a case of 59-year-old male with RA and a history of smoking and methotrexate (MTX) treatment, who developed dyspnoea, non-productive cough, and fever about two months after the administration of LEF. The clinical and radiological presentation was of acute pneumonia. The patient was treated with methylprednisolone pulse, prednisone, and cyclophosphamide, but he died of respiratory failure. PMID: 25339568 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Siemion-Szcześniak I, Bartoszuk I, Bartosiewicz M, Jakubowska L, Wesołowski S, Kuś J Tags: Pneumonol Alergol Pol Source Type: research

[Mycobacterial lung disease in patients with cystic fibrosis - report of three cases].
Abstract Mycobacterial lung disease is caused by nontuberculous mycobacteria (NTM), also known as atypical mycobacteria. NTM are widely distributed in the environment, particularly in soil and water. Although generally of low pathogenicity to humans, NTM can affect patients with underlying chronic lung diseases, such as cystic fibrosis, bronchiectasis, pneumoconiosis, or healed tuberculosis. Some patients with cystic fibrosis (CF) have disease progression due to NTM, others can have NTM cultured intermittently from respiratory specimens without a significant decline in lung function. Identifying which patients will...
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Wyrostkiewicz D, Skorupa W, Jakubowska L, Zabost A, Kuś J Tags: Pneumonol Alergol Pol Source Type: research

[Liposarcoma - a rare primary neoplasm of the thorax].
We present a case of a 35-year-old woman with a giant tumour of the left hemithorax, who had two weeks history of non-productive cough and progressive dyspnoea from eight months. Chest radiography showed a large, round opacity in the left hemithorax, which displaced the cardiac silhouette to the right. Contrast-enhanced computed tomography showed a huge, heterogeneous, well-circumscribed mass in the left pleural cavity. The tumour expanded locally towards the thoracic wall and left lung, and displaced mediastinal structures to the right. There was no lymphadenopathy on the physical examination and CT scan. Abdominal ultras...
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Załęska M, Langfort R, Oniszh K, Roszkowska-Śliż B, Roszkowski-Śliż K Tags: Pneumonol Alergol Pol Source Type: research

[False positive result of 18F-FDG PET in patient with lung cancer due to sarcoid-like reaction in regional lymph nodes].
Abstract The development of non-caseating granulomas in patients with neoplastic diseases is referred to as a sarcoid-like reaction. This reaction may be found in the primary tumour or near it; however, it is commonly seen in the regional lymph nodes, and usually subsides after treatment of the underlying disease. The pathogenesis of this process has not been fully explained. Sarcoid-like reactions occur in 4.4% of solid tumours, 7.3% of patients with non-Hodgkin's lymphoma, and 13.8% of patients with Hodgkin's lymphoma. The radiological image of increased lymph nodes due to the sarcoid-like reaction is similar to ...
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Kuś E, Gabryś J, Czyżewski D Tags: Pneumonol Alergol Pol Source Type: research

[Synchronous multiple primary lung cancers in a 65-year old heavy smoker. Case report].
Abstract Here we present a 65-year old ex-smoker with history of recent surgery for vocal cord tumor (histology: moderate grade intraepithelial neoplasia), who reported to the pulmonary outpatient clinic for the nodular lesions in the left lung seen on chest X-ray. Subsequent chest CT scan revealed focal lesion of 18 mm in diameter with spicular margins located in the right upper lobe, another irregular cyst with septa, 62 × 58 mm in the right lower lobe, and calcified nodule in the left lung, no enlarged lymph nodes or pleural effusion was seen. He underwent upper right lobe resection and wedge resection of the l...
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Swietlik EM, Doboszyńska A, Kupis W, Szołkowska M, Opoka L Tags: Pneumonol Alergol Pol Source Type: research

Effects of pulmonary rehabilitation on Fatigue Severity Scale in patients with lung disease.
CONCLUSIONS: Patients with advanced lung disease reported a measurable component of fatigue. Participating in pulmonary rehabilitation resulted in significant improvement in patient's self-reported fatigue severity. Further studies are necessary to evaluate and design interventions to improve fatigue in in the setting of advanced lung disease. PMID: 25339563 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Talwar A, Sahni S, John S, Verma S, Cárdenas-Garcia J, Kohn N Tags: Pneumonol Alergol Pol Source Type: research

Methotrexate as a single agent for treating pulmonary sarcoidosis: a single centre real-life prospective study.
CONCLUSIONS: MTX as a single agent in the treatment of sarcoidosis has proved to be a safe and effective steroid alternative. Selected patients with chronic pulmonary sarcoidosis experience definite PFT improvements after MTX treatment. There is need to search for predictors of MTX treatment effectiveness. PMID: 25339562 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Goljan-Geremek A, Bednarek M, Franczuk M, Puścińska E, Nowiński A, Czystowska M, Kamiński D, Korzybski D, Stokłosa A, Kowalska A, Wojda E, Sliwiński P, Burakowska B, Ptak J, Barańska I, Drygalska A, Małek G, Bestry I, Wesołowski S, Kram M, Górec Tags: Pneumonol Alergol Pol Source Type: research

Chronic obstructive pulmonary disease in Poland: distribution of patients according to the new GOLD 2011 classification. Cross-sectional survey.
CONCLUSIONS: In a large group of patients, representative of the population of COPD patients in Poland, we observed an uneven distribution of patients in the GOLD 2011 categories, with 71% of patients assigned to category A or D. In our study, the main reason for classifying to category C or D was the high risk of disease exacerbation rather than the degree of FEV1 reduction, as noted in other reports. PMID: 25339561 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Wesołowski S, Boros PW, Dębowski T Tags: Pneumonol Alergol Pol Source Type: research

The influence of sublingual immunotherapy on several parameters of immunological response in children suffering from atopic asthma and allergic rhinitis depending on asthma features.
CONCLUSIONS: Based on our results, we cannot point to any subgroup isolated in the study, in which the response of the immunological system to sublingual immunotherapy is more satisfactory than any other. Nevertheless, the increase of Th1 cells may be more specific for polysensitised children. PMID: 25339560 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Ciepiela O, Zawadzka-Krajewska A, Kotuła I, Demkow U Tags: Pneumonol Alergol Pol Source Type: research

Non-tuberculous mycobacterial lung disease (NT MLD ) in patients with chronic thromboembolic pulmonary hypertension and idiopathic pulmonary arterial hypertension.
CONCLUSIONS: NTMLD should be suspected in patients with CTEPH or IPAH, presenting with productive cough and a new pulmonary infiltrate with cavitation. In patients with CTEPH, special attention should be paid to a new cavitary lesions without accompanying thrombus in the artery supplying the area. High mPAP (CTEPH/IPAH) and hypoperfusion (CTEPH) are predisposing to NTMLD. PMID: 25339559 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Wilińska E, Oniszh K, Augustynowicz-Kopeć E, Zabost A, Fijałkowska A, Kurzyna M, Wieteska M, Torbicki A, Kuś J, Szturmowicz M Tags: Pneumonol Alergol Pol Source Type: research

The utility of oesophageal pH monitoring in diagnosing gastroesophageal reflux disease-related chronic cough.
CONCLUSIONS: Based on pH monitoring results, GERD was diagnosed twice as often as GERD-related cough. SAP index is more sensitive than SI for the diagnosis of GERD-related cough. PMID: 25339558 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Rybka A, Malesa K, Radlińska O, Krakowiak K, Grabczak EM, Dąbrowska M, Chazan R Tags: Pneumonol Alergol Pol Source Type: research

[Non-tuberculous mycobacterial lung disease. Rare entity or emerging epidemiological problem?].
PMID: 25339557 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Rowińska-Zakrzewska E Tags: Pneumonol Alergol Pol Source Type: research

[Microbiome of the lung].
PMID: 25339556 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - October 27, 2014 Category: Respiratory Medicine Authors: Górecka D, Puścińska E Tags: Pneumonol Alergol Pol Source Type: research

Am J Respir Cell Mol Biol; +16 new citations
16 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Respir Cell Mol Biol These pubmed results were generated on 2014/10/27PubMed, a service of the National Library of Medicine, includes over 15 million citations for biomedical articles back to the 1950's. These citations are from MEDLINE and additional life science journals. PubMed includes links to many sites providing full text articles and other related resources. (Source: Am J Respir Cell Mol...)
Source: Am J Respir Cell Mol... - October 27, 2014 Category: Respiratory Medicine Tags: Report Source Type: research

Small interfering RNA against CD86 during allergen challenge blocks experimental allergic asthma
Conclusion: These results suggest that local administration of CD86 siRNA during the effector phase ameliorates lines of asthma phenotypes. Targeting airway dendritic cells with siRNA suppresses airway inflammation and hyperresponsiveness in an experimental model of allergic asthma. (Source: Respiratory Research)
Source: Respiratory Research - October 27, 2014 Category: Respiratory Medicine Authors: Yukari Asai-TajiriKoichiro MatsumotoSatoru FukuyamaKeiko Kan-oTakako NakanoKen TonaiTatsukuni OhnoMiyuki AzumaHiromasa InoueYoichi Nakanishi Source Type: research

Intralesional bevacizumab in patients with Human immunodeficiency virus‐associated Kaposi's sarcoma in the upper airway
ConclusionsIntralesional administration of bevacizumab was well tolerated but had no impact on upper respiratory tract Kaposi's sarcoma lesions of HIV‐infected patients. Level of Evidence1b Laryngoscope, 2014 (Source: The Laryngoscope)
Source: The Laryngoscope - October 27, 2014 Category: ENT & OMF Authors: Yuria Ablanedo‐Terrazas, Claudia Alvarado‐de la Barrera, Christopher E. Ormsby, Matilde Ruiz‐Cruz, Gustavo Reyes‐Terán Tags: Head and Neck Source Type: research

Expression of soluble triggering receptor expressed on myeloid cells‐1 in childhood CF and Non‐CF bronchiectasis
ConclusionThe pulmonary innate immune functions are over‐active in HIV‐associated bronchiectasis, with readily detected sTREM‐1 values, which were higher than those in CF. sTREM‐1 does not correlate with markers of HIV‐disease activity but does correlate with markers of neutrophilic inflammation. In CF sTREM‐1 has a negative correlation with pulmonary function parameters. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - October 27, 2014 Category: Respiratory Medicine Authors: R. Masekela, R. Anderson, K. de Boeck, M. Vreys, H.C. Steel, S. Olurunju, R.J. Green Tags: Original Article Source Type: research

Gender‐ and age‐specific risk factors for wheeze from birth through adolescence
ConclusionUsing a prospective cohort, we identified gender‐ and age‐specific risk factors for wheeze. The identification of gender‐specific early life risk factors may allow for timely interventions and a more personalized approach to the treatment of asthma. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - October 27, 2014 Category: Respiratory Medicine Authors: Sze Man Tse, Brent A. Coull, Joanne E. Sordillo, Soma Datta, Diane R. Gold Tags: Original Article Source Type: research

Monotherapy with indacaterol once daily reduces the rate of exacerbations in patients with moderate-to-severe COPD: Post-hoc pooled analysis of 6 months data from three large phase III trials
In patients with COPD, exacerbations are associated with poor quality of life and may shorten survival. Prevention of exacerbations is, therefore, a key objective in COPD management. Indacaterol, a once-daily ultra-long acting β2-agonist, has been shown to reduce exacerbations in various studies. This pooled analysis evaluated the effect of indacaterol on exacerbations versus placebo. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - October 27, 2014 Category: Respiratory Medicine Authors: Jadwiga A. Wedzicha, Roland Buhl, David Lawrence, David Young Source Type: research

Telehealthcare in COPD: a systematic review and meta-analysis on physical outcomes and dyspnea
Only a minority of patients with chronic obstructive pulmonary disease (COPD) have access to pulmonary rehabilitation (PR). Home-based solutions such as telehealthcare, have been used in efforts to make PR more available. The aim of this systematic review was to investigate the effects of telehealthcare on physical activity level, physical capacity and dyspnea in patients with COPD, and to describe the interventions used. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - October 27, 2014 Category: Respiratory Medicine Authors: Sara Lundell, Åsa Holmner, Börje Rehn, Andre Nyberg, Karin Wadell Tags: Review Source Type: research

Heterogeneity of phenotypes in severe asthmatics. The Belgian Severe Asthma Registry (BSAR)
The Belgian severe asthma registry is a web-based registry encompassing demographic, clinical, functional and inflammatory data of severe asthmatics (SA), aiming at improving awareness, knowledge on its natural history and subphenotypes, and offering tools to optimize care of this asthma population. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - October 27, 2014 Category: Respiratory Medicine Authors: F. Schleich, G. Brusselle, R. Louis, O. Vandenplas, A. Michils, C. Pilette, R. Peche, M. Manise, G. Joos Source Type: research

The association of exposure to hepatitis B and C viruses with lung function and respiratory disease: A population based study from the NHANES III database
Globally, 500 million people are chronically infected with Hepatitis B virus (HBV) and Hepatitis C virus (HCV). While these viruses are notorious for their detrimental effect on the liver they are also known to affect multiple organs in the body including the lungs. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - October 27, 2014 Category: Respiratory Medicine Authors: Li Yen Goh, Tim Card, Andrew W. Fogarty, Tricia M. McKeever Source Type: research

Aggregates of mutant CFTR fragments in airway epithelial cells of CF lungs: New pathologic observations
Cystic fibrosis (CF) is caused by a mutation in the CF transmembrane conductance regulator (CFTR) gene resulting in a loss of Cl− channel function, disrupting ion and fluid homeostasis, leading to severe lung disease with airway obstruction due to mucus plugging and inflammation. The most common CFTR mutation, F508del, occurs in 90% of patients causing the mutant CFTR protein to misfold and trigger an endoplasmic reticulum based recycling response. Despite extensive research into the pathobiology of CF lung disease, little attention has been paid to the cellular changes accounting for the pathogenesis of CF lung disease....
Source: Journal of Cystic Fibrosis - October 27, 2014 Category: Respiratory Medicine Authors: Kai Du, Philip H. Karp, Cameron Ackerley, Joseph Zabner, Shaf Keshavjee, Ernest Cutz, Herman Yeger Tags: Original Article Source Type: research

Asthma associated with pesticide exposure among women in rural Western Cape of South Africa
ConclusionPesticide exposure among women farm workers is associated with increased risk of ocular nasal symptoms and an elevated asthma symptom score. Am. J. Ind. Med. © 2014 Wiley Periodicals, Inc. (Source: American Journal of Industrial Medicine)
Source: American Journal of Industrial Medicine - October 27, 2014 Category: Occupational Health Authors: Vuyelwa Ndlovu, Mohamed Aqiel Dalvie, Mohamed F. Jeebhay Tags: Research Article Source Type: research

Restrictive Transfusion Practice During Extracorporeal Membrane Oxygenation Therapy for Severe Acute Respiratory Distress Syndrome
We report on a series of patients receiving venovenous ECMO (vvECMO) for acute respiratory distress syndrome (ARDS) treated according to the restrictive transfusion regimen recommended for critically ill patients. We retrospectively analyzed 18 patients receiving vvECMO due to severe ARDS. Hemoglobin concentrations were kept between 7 and 9 g/dL with a transfusion trigger at 7 g/dL or when physiological transfusion triggers were apparent. We assessed baseline data, hospital mortality, time on ECMO, hemoglobin levels, hematocrit, quantities of packed red blood cells received, and lactate concentrations and compared surv...
Source: Artificial Organs - October 27, 2014 Category: Transplant Surgery Authors: Maria T. Voelker, Thilo Busch, Sven Bercker, Falk Fichtner, Udo X. Kaisers, Sven Laudi Tags: Thoughts and Progress Source Type: research

Extracorporeal Membrane Oxygenation as a Bridge to Clinical Recovery in Life-Threatening Autoimmune Acute Respiratory Distress Syndrome
ACUTE RESPIRATORY FAILURE is a rare but possible initial presentation of an autoimmune disease such as systemic lupus erythematosus. The diffuse alveolar edema that typically is a feature of this life-threatening presentation may prove refractory to multimodal aggressive medical management in the intensive care unit. This case conference explores the application of extracorporeal membrane oxygenation in this setting as a life-saving bridge to clinical recovery. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - October 27, 2014 Category: Anesthesiology Authors: Zev Noah Kornfield, Jiri Horak, Robin M. Gibbs, Stuart J. Weiss, Pavan Atluri, John G.T. Augoustides, Jacob T. Gutsche, David Sidebotham Tags: Case Conference Source Type: research

Isolation of Epithelial, Endothelial, and Immune Cells From Lungs of Transgenic Mice with Oncogene-Induced Lung Adenocarcinomas.
In this study, we optimized magnetic and fluorescence-based isolation protocols to segregate lung epithelial (CD326/EpCAM positive), endothelial (CD31 positive), and immune cells (CD45 positive), with high purity, from the lungs of transgenic mice with mutant EGFR-induced lung adenocarcinomas. This approach, which can potentially be extended to additional lung adenocarcinoma models, enables delineation of the molecular features of individual cell types that can be used to gain insight into their roles in lung adenocarcinoma initiation, progression, and response to therapy. PMID: 25347711 [PubMed - as supplied by publis...
Source: American Journal of Respiratory Cell and Molecular Biology - October 27, 2014 Category: Molecular Biology Authors: Bantikassegn A, Song X, Politi K Tags: Am J Respir Cell Mol Biol Source Type: research

Src Regulates Cigarette Smoke-induced Ceramide Generation via nSMase2 in the Airway Epithelium.
This study provides insights into a molecular target involved in smoking-related lung injury, represented here as nSMase2, and its modulation by the oncogene Src. PMID: 25347576 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - October 27, 2014 Category: Molecular Biology Authors: Chung S, Vu S, Filosto S, Goldkorn T Tags: Am J Respir Cell Mol Biol Source Type: research

Serum 25-hydroxyvitamin D, mortality, and incident cardiovascular disease, respiratory disease, cancers, and fractures: a 13-y prospective population study.
CONCLUSIONS: Plasma 25(OH)D concentrations predict subsequent lower 13-y total mortality and incident cardiovascular disease, respiratory disease, and fractures but not total incident cancers. For mortality, lowest risks were in subjects with concentrations >90 nmol/L, and there was no evidence of increased mortality at high concentrations, suggesting that a moderate increase in population mean concentrations may have potential health benefit, but <1% of the population had concentrations >120 nmol/L. PMID: 25332334 [PubMed - in process] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 26, 2014 Category: Nutrition Authors: Khaw KT, Luben R, Wareham N Tags: Am J Clin Nutr Source Type: research

Validating an energy expenditure prediction equation in overweight and obese mexican patients.
VALIDATING AN ENERGY EXPENDITURE PREDICTION EQUATION IN OVERWEIGHT AND OBESE MEXICAN PATIENTS. Nutr Hosp. 2014;30(n04):749-755 Authors: Quiroz-Olguín G, Serralde-Zúñiga AE, Saldaña-Morales MV, Gulias-Herrero A, Guevara-Cruz M Abstract Background: The prevalence of overweight and obesity in Mexico is approximately 70%; thus, obtaining a reliable measurement of the resting energy expenditure (REE) in these patients is of extreme importance. The aim of the study was to obtain a prediction equation of REE in overweight or obese outpatients in the Mexican population. Methods: The study was conducted at ...
Source: Nutricion Hospitalaria - October 26, 2014 Category: Nutrition Authors: Quiroz-Olguín G, Serralde-Zúñiga AE, Saldaña-Morales MV, Gulias-Herrero A, Guevara-Cruz M Tags: Nutr Hosp Source Type: research

Infusion of Mesenchymal Stem Cells Protects Lung Transplants from Cold Ischemia-Reperfusion Injury in Mice
Conclusions MSCs provide significant protection against cold IRI in lung transplants, and thus may be a promising strategy to improve outcomes after lung transplantation. (Source: Lung)
Source: Lung - October 26, 2014 Category: Respiratory Medicine Source Type: research