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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 3.

The relationship between widespread changes in gravity and cerebral blood flow
Conclusion The present study demonstrated stepwise gravity-induced changes in steady-state CBFV from 0.5 to 2.0 Gz despite unchanged steady-state MAPHeart. The combined effects of reduced MAPMCA and ETCO2 likely led to stepwise decreases in CBFV. We caution that a mild increase in gravity from 0 to 2.0 Gz reduces CBF, even if arterial blood pressure at the heart level is maintained. (Source: Environmental Health and Preventive Medicine)
Source: Environmental Health and Preventive Medicine - February 9, 2016 Category: Environmental Health Source Type: research

RSV enhances P. aeruginosa biofilm growth [Microbiology]
Clinical observations link respiratory virus infection and Pseudomonas aeruginosa colonization in chronic lung disease, including cystic fibrosis (CF) and chronic obstructive pulmonary disease. The development of P. aeruginosa into highly antibiotic-resistant biofilm communities promotes airway colonization and accounts for disease progression in patients. Although clinical studies show a strong correlation... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - February 9, 2016 Category: Science Authors: Hendricks, M. R., Lashua, L. P., Fischer, D. K., Flitter, B. A., Eichinger, K. M., Durbin, J. E., Sarkar, S. N., Coyne, C. B., Empey, K. M., Bomberger, J. M. Tags: Biological Sciences Source Type: research

Palmitate-induced impairment of glucose-stimulated insulin secretion precedes mitochondrial dysfunction in mouse pancreatic islets
It has been well established that excessive levels of glucose and palmitate lower glucose-stimulated insulin secretion (GSIS) by pancreatic β-cells. This β-cell ‘glucolipotoxicity’ is possibly mediated by mitochondrial dysfunction, but involvement of bioenergetic failure in the pathological mechanism is the subject of ongoing debate. We show in the present study that increased palmitate levels impair GSIS before altering mitochondrial function. We demonstrate that GSIS defects arise from increased insulin release under basal conditions in addition to decreased insulin secretion under glucose-stimulato...
Source: Biochemical Journal - February 9, 2016 Category: Biochemistry Authors: Barlow, J., Jensen, V. H., Jastroch, M., Affourtit, C. Tags: Energy, Metabolism Research articles Source Type: research

Retrospective evaluation of patients at follow-up with acute poisoning in Intensive Care Unit
Conclusion: Suicide attempts are prominent in acute poisoning, and the young female population is at higher risk. It was found that drugs, particularly antidepressants and antipsychotic agents were the most common cause of poisoning. The high cost of treatment of acute intoxication cases is a major cause of economic burden. Clinicians should be more careful when prescribing such drugs. (Source: Nigerian Journal of Clinical Practice)
Source: Nigerian Journal of Clinical Practice - February 9, 2016 Category: Rural Health Authors: S YaylaciAB GençMV DemirH CinemreA Tamer Source Type: research

High-flow nasal cannula: Mechanisms, evidence and recommendations
The use of high-flow nasal cannula (HF) therapy as respiratory support for preterm infants is rapidly increasing, due to its perceived ease of use and other potential benefits over the standard ‘non-invasive’ respiratory support, continuous positive airway pressure (CPAP). The evidence from randomized trials suggests that HF is an alternative to CPAP for post-extubation support of preterm infants. Limited data are available from randomized trials comparing HF with CPAP as primary support, and few trials have included extremely preterm infants. (Source: Seminars in Fetal and Neonatal Medicine)
Source: Seminars in Fetal and Neonatal Medicine - February 9, 2016 Category: Perinatology & Neonatology Authors: Brett J. Manley, Louise S. Owen Tags: Review Source Type: research

Intercellular adhesion molecule 1 serves as a primary cognate receptor for the Type IV pilus of nontypeable Haemophilus influenzae
Summary Nontypeable Haemophilus influenzae (NTHI) utilizes the Type IV pilus (Tfp) to adhere to respiratory tract epithelial cells thus colonizing its human host; however the host cell receptor to which this adhesive protein binds is unknown. From a panel of receptors engaged by Tfp expressed by other bacterial species, we showed that the majority subunit of NTHI Tfp, PilA, bound to intercellular adhesion molecule 1 (ICAM1) and that this interaction was both specific and of high affinity. Further, Tfp‐expressing NTHI inoculated on to polarized respiratory tract epithelial cells that expressed ICAM1 were significantly mor...
Source: Cellular Microbiology - February 9, 2016 Category: Microbiology Authors: Laura A. Novotny, Lauren O. Bakaletz Tags: Research article Source Type: research

Adipocyte versus Somatotrope Leptin: Regulation of Metabolic Functions in the Mouse.
This study tests the hypothesis that the pituitary somatotrope may contribute a source of leptin that maintains some of these metabolic functions. We created two different tissue-specific leptin knockout animals: a Somatotrope-Lep-null model and an Adipocyte-Lep-null model. Metabolic analysis of both models, along with a global deletion model, was performed. The Somatotrope-Lep-null animals had fewer somatotropes, and females had a 76% decrease in serum prolactin. During the dark (feeding) phase, females had a 35% increase in ambulation coupled with a 4% increase in energy expenditure. Mutants showed no change in food inta...
Source: Endocrinology - February 9, 2016 Category: Endocrinology Authors: Odle AK, Allensworth-James M, Haney A, Akhter N, Syed M, Childs GV Tags: Endocrinology Source Type: research

Clinical Outcomes in Outpatient Respiratory Syncytial Virus Infection in Immunocompromised Children
ConclusionsMost immunocompromised children with RSV detected while outpatients did not require hospitalization or receive antiviral treatment. Potential studies of RSV therapies should consider inclusion of patients in an ambulatory setting.This article is protected by copyright. All rights reserved. (Source: Influenza and Other Respiratory Viruses)
Source: Influenza and Other Respiratory Viruses - February 9, 2016 Category: Virology Authors: Helen Y. Chu, Jennifer Chin, Jessica Pollard, Danielle M. Zerr, Janet A. Englund Tags: Original Article Source Type: research

What works and what's safe in pediatric emergency procedural sedation: an overview of reviews.
This article is protected by copyright. All rights reserved. PMID: 26858095 [PubMed - as supplied by publisher] (Source: Accident and Emergency Nursing)
Source: Accident and Emergency Nursing - February 9, 2016 Category: Emergency Medicine Authors: Hartling L, Milne A, Foisy M, Lang E, Sinclair D, Klassen TP, Evered L Tags: Acad Emerg Med Source Type: research

Skeletal muscle regeneration in cancer cachexia.
This article is protected by copyright. All rights reserved. PMID: 26857538 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Pharmacology and Physiology)
Source: Clinical and Experimental Pharmacology and Physiology - February 9, 2016 Category: Drugs & Pharmacology Authors: Bossola M, Marzetti E, Rosa F, Pacelli F Tags: Clin Exp Pharmacol Physiol Source Type: research

Contemporary reproductive outcomes for patients with polycystic ovary syndrome: a retrospective observational study.
CONCLUSIONS: PCOS is associated with subfertility but fertility rates are restored to those of the background population following diagnosis. Pregnancy complications and adverse neonatal outcomes are more prevalent for women with PCOS independently of obesity. PMID: 26859102 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - February 9, 2016 Category: Endocrinology Authors: Rees DA, Jenkins-Jones S, Morgan CL Tags: J Clin Endocrinol Metab Source Type: research

Severe rhabdomyolysis secondary to adenovirus infection: case report and literature review.
Abstract A 38-year-old male presented with renal failure in the setting of a flu-like illness. Urinalysis showed myoglobinuria and granular casts. His serum creatine phosphokinase was markedly elevated. He was diagnosed with rhabdomyolysis and was volume resuscitated with normal saline and bicarbonate-containing fluid. Workup included a respiratory viral panel which was positive for adenovirus. Other causes such as trauma, seizure, and intoxicants were excluded. He developed progressive renal failure necessitating hemodialysis. After ~ 4 weeks he recovered renal function and dialysis was discontinued. Viral-induced...
Source: Clinical Nephrology - February 9, 2016 Category: Urology & Nephrology Authors: Tseytlin D, Maynard S Tags: Clin Nephrol Source Type: research

Multiple antibiotic resistance index, fitness and virulence potential in respiratory Pseudomonas aeruginosa from Jamaica.
Abstract Respiratory infections are common causes of morbidity and mortality worldwide. We sought to assess the multiple antibiotic resistance (MAR) index, fitness, and virulence potential in Pseudomonas aeruginosa from patients with lower respiratory tract infections. Isolates were assessed for antimicrobial susceptibility, in vitro competitive fitness, pigment, elastase and rhamnolipid production. Oxidative stress tolerance was determined on both planktonic and biofilm cells and virulence potential was tested in a plant model. Mean MAR index for isolates was 0.34 (range, 0.17 - 0.50). While isolates exhibited go...
Source: Journal of Medical Microbiology - February 9, 2016 Category: Microbiology Authors: Davis R, Brown PD Tags: J Med Microbiol Source Type: research

Outcome of Adult Respiratory Failure Patients Receiving Prolonged (≥14 Days) ECMO
Conclusions: Prolonged ECMO use for adult respiratory failure was associated with a lower (45.4%) hospital survival rate, compared with prior reported survival rates of short duration ECMO. Prolonged ECMO survival significantly increased in recent years, and increasing ECMO duration did not alter the survival fraction in the 1989 to 2013 study cohort. Although P-ECMO survival rates are less than short ECMO runs, P-ECMO support is justified. (Source: Annals of Surgery)
Source: Annals of Surgery - February 8, 2016 Category: Surgery Tags: Original Articles Source Type: research

Association of FEF25-75% Impairment with Bronchial Hyperresponsiveness and Airway Inflammation in Subjects with Asthma-Like Symptoms
Background: Forced expiratory flow at 25 and 75% of the pulmonary volume (FEF25-75%) might be considered as a marker of early airway obstruction. FEF25-75% impairment might suggest earlier asthma recognition in symptomatic subjects even in the absence of other abnormal spirometry values. Objectives: The study was designed in order to verify whether FEF25-75% impairment in a cohort of subjects with asthma-like symptoms could be associated with the risk of bronchial hyperresponsiveness (BHR) and with airway inflammation expressed as fractional exhaled nitric oxide (FeNO) and eosinophil counts in induced sputum. Methods: Four...
Source: Respiration - February 8, 2016 Category: Respiratory Medicine Source Type: research

Colchicine Treatment for Tracheobronchial Amyloidosis
We report a case of a 63-year-old woman who presented with a diffuse tracheobronchial amyloidosis associated with laryngeal involvement, which required a percutaneous tracheostomy due to high-grade subglottic stenosis, with no evidence of systemic amyloidosis. After treatment exclusively with colchicine, she had a complete resolution of the stenotic area, with a very good response from the tracheobronchial amyloidosis disease, with only minor yellow plaques persisting. The patient has remained asymptomatic in the next 4 years of follow-up, with no evidence of endoscopic progression. This is the first documented case of thi...
Source: Respiration - February 8, 2016 Category: Respiratory Medicine Source Type: research

Novel CeO2-CuO-decorated enzymatic lactate biosensors operating in low oxygen environments.
Abstract The detection of the lactate level in blood plays a key role in diagnosis of some pathological conditions including cardiogenic or endotoxic shocks, respiratory failure, liver disease, systemic disorders, renal failure, and tissue hypoxia. Here, we described for the first time the use of a novel mixed metal oxide solution system to address the oxygen dependence challenge of first generation amperometric lactate biosensors. The biosensors were constructed using ceria-copper oxide (CeO2-CuO) mixed metal oxide nanoparticles for lactate oxidase immobilization and as electrode material. The oxygen storage capac...
Source: Analytica Chimica Acta - February 8, 2016 Category: Chemistry Authors: Uzunoglu A, Stanciu LA Tags: Anal Chim Acta Source Type: research

Sublabial Autologous Ear Cartilage Grafting for Increasing the Nasolabial Angle.
CONCLUSIONS: The surgical method described here is simple and can be learned quickly. It has very good results with few complications, and is our method of choice for complex and serious cases seen in everyday rhinosurgical practice. PMID: 26848445 [PubMed] (Source: Archives of Plastic Surgery)
Source: Archives of Plastic Surgery - February 8, 2016 Category: Cosmetic Surgery Tags: Arch Plast Surg Source Type: research

Measurement of oxygen extraction fraction (OEF): An optimized BOLD signal model for use with hypercapnic and hyperoxic calibration
Publication date: 1 April 2016 Source:NeuroImage, Volume 129 Author(s): Alberto Merola, Kevin Murphy, Alan J. Stone, Michael A. Germuska, Valerie E.M. Griffeth, Nicholas P. Blockley, Richard B. Buxton, Richard G. Wise Several techniques have been proposed to estimate relative changes in cerebral metabolic rate of oxygen consumption (CMRO2) by exploiting combined BOLD fMRI and cerebral blood flow data in conjunction with hypercapnic or hyperoxic respiratory challenges. More recently, methods based on respiratory challenges that include both hypercapnia and hyperoxia have been developed to assess absolute CMRO2, an...
Source: NeuroImage - February 8, 2016 Category: Neuroscience Source Type: research

Prevalence of rhinovirus in wheezing children: a comparison with respiratory syncytial virus wheezing
Conclusion Rhinovirus was a main viral pathogen in wheezing children, especially in summer time. Rhinovirus-induced wheezing was different from respiratory syncytial virus, apart from seasonal epidemics; these two groups differed with regard to age, allergic sensitizations, laboratory test, and history of wheezing episodes. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - February 8, 2016 Category: Infectious Diseases Source Type: research

Dementia in Parkinson's disease is associated with enhanced mitochondrial complex I deficiency
ConclusionsPatients with PDD have a deficiency in mitochondrial complex I activity and reduced mitochondrial DNA levels in the prefrontal cortex without a change in mitochondrial protein quantity. Therefore, mitochondrial complex I deficiency and reduced mitochondrial DNA in the prefrontal cortex may be a hallmark of dementia in patients with PD. © 2016 International Parkinson and Movement Disorder Society (Source: Movement Disorders)
Source: Movement Disorders - February 8, 2016 Category: Neurology Authors: Ariana P. Gatt, Olivia F. Duncan, Johannes Attems, Paul T. Francis, Clive G. Ballard, Joseph M. Bateman Tags: Research Article Source Type: research

Wheezing Patterns in Early Childhood
This study applied the Tuscon Children’s Respiratory Study wheeze phenotypes to the high-risk Canadian Asthma Primary Prevention Study cohort and evaluated associations with pulmonary function, asthma, and allergic disease in adolescence. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - February 8, 2016 Category: Pediatrics Source Type: research

Issue Information ‐ TOC
(Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - February 8, 2016 Category: Respiratory Medicine Tags: Issue Information ‐ TOC Source Type: research

Upcoming events of interest
(Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - February 8, 2016 Category: Respiratory Medicine Tags: Upcoming Events Source Type: research

A case of brucellosis presenting with pericardial and pleural effusion
(Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 8, 2016 Category: Respiratory Medicine Authors: Meryem Hilal Altas, Arzu Karli, Gulnar Sensoy, Ozlem Koken, Burak Yurek, Kemal Baysal Tags: Case Report Source Type: research

Successful Balloon Pulmonary Angioplasty with Gadolinium Contrast Media for a Patient with Chronic Thromboembolic Pulmonary Hypertension and Iodine Allergy
Publication date: Available online 8 February 2016 Source:Respiratory Medicine Case Reports Author(s): Tomohisa Nakamura, Takeshi Ogo, Akihiro Tsuji, Shigefumi Fukui, Tetsuya Fukuda, Nobuhiro Tahara, Yoshihiro Fukumoto, Satoshi Yasuda, Hisao Ogawa, Norifumi Nakanishi A 28-year-old male was referred to our hospital with dyspnea. He was diagnosed as having chronic thromboembolic pulmonary hypertension, and a pulmonary endarterectomy (PEA) was performed. However, exertional dyspnea remained because of residual pulmonary hypertension; therefore, the patient was re-admitted to our hospital 1 year after PEA. We perfo...
Source: Respiratory Medicine Case Reports - February 8, 2016 Category: Respiratory Medicine Source Type: research

Tracheomegaly and tracheosephagial fistula following mechanical ventilation: A case report and review of the literature
We present a case of both tracheomegaly and tracheosephagial fistula following mechanical ventilation for 15 days, in the light of the literature. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - February 8, 2016 Category: Respiratory Medicine Source Type: research

A case of recurrent massive pulmonary embolism in Klippel–Trenaunay–Weber syndrome treated with thrombolytics
Publication date: 2016 Source:Respiratory Medicine Case Reports, Volume 17 Author(s): Hinesh Upadhyay, Khalid Sherani, Abhay Vakil, Mohammed Babury Klippel – Trenaunay – Weber syndrome (KTWS) is a congenital condition characterized by a triad of capillary malformations of the skin, soft tissue and bone hypertrophy resulting in limb enlargement, and abnormalities of arteriovenous and lymphatic systems of the affected limb. In this case, we present a patient with KTWS receiving chronic anticoagulation that had a massive pulmonary embolism and was successfully treated with thrombolytic therapy. The purpose of this c...
Source: Respiratory Medicine Case Reports - February 8, 2016 Category: Respiratory Medicine Source Type: research

Various clinical conditions can mimic Crimean-Congo hemorrhagic fever in pediatric patients in endemic regions
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease with high mortality. Many disorders can mimic CCHF. It is important to recognize the condition and to perform differential diagnosis in endemic countries. Twenty-one children aged 18 years or less with a preliminary diagnosis of CCHF were retrospectively evaluated. Real-time PCR and a confirmatory indirect immunofluorescence assay for negative results were performed. The diagnoses determined that 9 patients had (42.9%) CCHF; 7 patients had (33.3%) viral upper respiratory tract infections (URTI); 2 patients had (9.5%) brucellosis; 1 patients had (4.7%) periodic ...
Source: Journal of Infection and Public Health - February 8, 2016 Category: Global & Universal Authors: Soner Sertan Kara, Duygu Kara, Ali Fettah Source Type: research

Acids and alkalis cause severe corrosive damage on contact with tissues. Topical exposure causes severe pain, blistering and ulceration. The most important aspect of management is decontamination with water until skin pH is normal. Inhalational exposure results in sore throat, cough, wheeze and respiratory distress. Hoarseness or stridor necessitates an urgent anaesthetic assessment and perhaps endotracheal intubation or tracheostomy. Ingestion causes severe pain, oropharyngeal burns and vomiting. (Source: Medicine)
Source: Medicine - February 8, 2016 Category: Internal Medicine Authors: Paul I. Dargan Tags: Specific substances Source Type: research

Alcohols and glycols
Ethanol is a central nervous system depressant and peripheral vasodilator, thereby causing coma, hypothermia and hypotension in severe poisoning. Hypoglycaemia, particularly in children, is observed together with acid–base disturbances, which are common (respiratory acidosis is observed more frequently than metabolic acidosis, and metabolic alkalosis may be observed in those vomiting and hypovolaemic). Lactic acidosis (usually mild) is an uncommon but potentially serious complication. Haemodialysis can be considered if the blood ethanol concentration exceeds 7500 mg/litre and severe metabolic acidosis is present. (Source: Medicine)
Source: Medicine - February 8, 2016 Category: Internal Medicine Authors: Allister Vale Tags: Specific substances Source Type: research

Immunopotentiation of four natural adjuvants co-administered with a highly pathogenic porcine reproductive and respiratory syndrome virus glycoprotein 5 subunit
In conclusion, from immune responses and immunological protection against HP-PRRSV, the Astragalus/Bacillus adjuvant demonstrated the most potent immunological enhancement effect on HP-PRRSV GP5 subunit. Astragalus/Bacillus adjuvant showed promise as a candidate immune adjuvant, to more efficiently prevent and control PRRS. (Source: Virus Genes)
Source: Virus Genes - February 8, 2016 Category: Genetics & Stem Cells Source Type: research

A comparison of clinical efficacy between high frequency oscillatory ventilation and conventional ventilation with lung volume recruitment in pediatric acute respiratory distress syndrome: A randomized controlled trial
Conclusions: HFOV combined with LVRM in severe pediatric ARDS had superior oxygenation and tended to have better clinical effect over CV. There is no significant effect on hemodynamic parameters. Moreover, no serious complication was noted. (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 8, 2016 Category: Intensive Care Authors: Rujipat SamransamruajkitChavisa RassameehirunKhemmachart PongsanonSumalee HuntrakulJitladda DeerojanawongSuchada SritippayawanNuanchan Prapphal Source Type: research

A rare aspect of Crohn's disease: Pulmonary involvement in a child
Ebru Atike Ongun, Reha Artan, Aysen Bingol, Oguz DursunIndian Journal of Critical Care Medicine 2016 20(2):114-116Crohn's disease (CD), known as the disease of gastrointestinal system, is a granulamatous systemic disorder with extraintestinal manifestations including the respiratory system. The resemblance in the embriological origins and the immunities of both organ systems' mucosae, also the circulating immune complexes and the autoantibodies are accepted as contributing factors. The shift of inflammation may become prominent when the colon is removed after colectomy and independent of the bowel dis...
Source: Indian Journal of Critical Care Medicine - February 8, 2016 Category: Intensive Care Authors: Ebru Atike OngunReha ArtanAysen BingolOguz Dursun Source Type: research

Noninvasive ventilation in acute respiratory distress syndrome: A long way ahead
Inderpaul Singh Sehgal, Sahajal Dhooria, Ritesh Agarwal, Dhruva ChaudhryIndian Journal of Critical Care Medicine 2016 20(2):129-130 (Source: Indian Journal of Critical Care Medicine)
Source: Indian Journal of Critical Care Medicine - February 8, 2016 Category: Intensive Care Authors: Inderpaul Singh SehgalSahajal DhooriaRitesh AgarwalDhruva Chaudhry Source Type: research

The transition from water-breathing to air-breathing is associated with a shift in ion uptake from gills to gut: a study of two closely related erythrinid teleosts, Hoplerythrinus unitaeniatus and Hoplias malabaricus
Abstract The evolutionary transition from water-breathing to air-breathing involved not only a change in function of the organs of respiratory gas exchange and N-waste excretion, but also in the organs of ion uptake from the environment. A combination of in vivo and in vitro techniques was used to look at the relative importance of the gills versus the gut in Na+, Cl−, and K+ balance in two closely related erythrinid species: a facultative air-breather, the jeju (Hoplerythrinus unitaeniatus) and an obligate water-breather, the traira (Hoplias malabaricus). The jeju has a well-vascularized physosto...
Source: Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology - February 8, 2016 Category: Physiology Source Type: research

Timing of influenza epidemics and vaccines in the American tropics, 2002–2008, 2011–2014
ConclusionsThe majority of countries in the American tropics have seasonal epidemics that start in May. Officials in these countries should consider the impact of vaccinating persons during April with the Southern Hemisphere formulation. (Source: Influenza and Other Respiratory Viruses)
Source: Influenza and Other Respiratory Viruses - February 8, 2016 Category: Virology Authors: Lizette Olga Durand, Po‐Yung Cheng, Rakhee Palekar, Wilfrido Clara, Jorge Jara, Mauricio Cerpa, Nathalie El Omeiri, Alba Maria Ropero‐Alvarez, Juliana Barbosa Ramirez, Jenny Lara Araya, Belsy Acosta, Alfredo Bruno, Celina Calderon de Lozano, Leticia d Tags: Original Article Source Type: research

Rationale and Prospects of Targeting Bacterial Two-component Systems for Antibacterial Treatment of Cystic Fibrosis Patients.
Abstract Bacterial respiratory infections are the main reason of morbidity and mortality among cystic fibrosis (CF) patients. In early childhood, the respiratory infections are due to Staphylococcus aureus and Haemophilus influenzae. In older CF patients, pathogenic Gram-negative bacteria like Achromobacter xylosoxidans, Burkholderia cepacia complex and especially Pseudomonas aeruginosa are more frequently seen. P. aeruginosa is a turning point in the respiratory disease in CF and its predominance increases with age. Bacteria use a variety of two-component systems (TCS) to differentially express virulence factors i...
Source: Current Drug Targets - February 8, 2016 Category: Drugs & Pharmacology Authors: Velikova N, Wellsa JM Tags: Curr Drug Targets Source Type: research

Adherence to Dietary Guidelines and Successful Aging Over 10 Years
Conclusions. Greater compliance with recommended national dietary guidelines (higher diet quality) was associated with an increased likelihood of successful aging, as determined through a multidomain approach. (Source: Journals of Gerontology Series A: Biological Sciences and Medical Sciences)
Source: Journals of Gerontology Series A: Biological Sciences and Medical Sciences - February 8, 2016 Category: Geriatrics Authors: Gopinath, B., Russell, J., Kifley, A., Flood, V. M., Mitchell, P. Tags: Research Article Source Type: research

Polio-Like Illness Associated With Outbreak of Upper Respiratory Tract Infection in Children
Poliomyelitis is a historically devastating neurological complication of poliovirus infection. Poliovirus vaccines have decreased the incidence of poliomyelitis to 209 global cases in 2014, with new cases of acute flaccid myelitis primarily associated with nonpolio enteroviruses. Recently, during outbreaks of enterovirus D68 throughout North America and Europe, cases of acute flaccid myelitis have been reported, suggesting another nonpolio enterovirus associated with acute flaccid myelitis. The authors describe 3 patients diagnosed with acute flaccid myelitis during a province-wide outbreak of enterovirus D68 with the viru...
Source: Journal of Child Neurology - February 8, 2016 Category: Neurology Authors: Crone, M., Tellier, R., Wei, X.-C., Kuhn, S., Vanderkooi, O. G., Kim, J., Mah, J. K., Mineyko, A. Tags: Original Articles Source Type: research

Antenatal corticosteroid administration before elective caesarean section at term to prevent neonatal respiratory morbidity: a randomized controlled trial
To assess the effect of prophylactic corticosteroid administration before elective caesarean section at term (between 38 and 38+6 weeks) in reducing neonatal respiratory morbidity and admission to a neonatal intensive care unit (NICU) with respiratory complications. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 8, 2016 Category: OBGYN Authors: A.M. Nada, M.M. Shafeek, M.A. El Maraghy, A.H. Nageeb, A.S. Salaheldine, M.H. Awad Source Type: research

Simultaneous reconstruction of the activity image and registration of the CT image in TOF-PET.
Abstract Previously, maximum-likelihood methods have been proposed to jointly estimate the activity image and the attenuation image or the attenuation sinogram from time-of-flight (TOF) positron emission tomography (PET) data. In this contribution, we propose a method that addresses the possible alignment problem of the TOF-PET emission data and the computed tomography (CT) attenuation data, by combining reconstruction and registration. The method, called MLRR, iteratively reconstructs the activity image while registering the available CT-based attenuation image, so that the pair of activity and attenuation images ...
Source: Physics in Medicine and Biology - February 8, 2016 Category: Physics Authors: Rezaei A, Michel C, Casey ME, Nuyts J Tags: Phys Med Biol Source Type: research

Haematospirillum jordaniae gen. nov., sp. nov., isolated from human blood samples.
Abstract A Gram-negative, aerobic, motile, spiral-shaped bacterium, strain H5569(T), was isolated from a human blood sample. Phenotypic and molecular characteristics of the isolate were investigated. Optimal growth was found to occur at 35 °C under aerobic conditions on Heart Infusion Agar supplemented with 5 % rabbit blood. The major fatty acids present in the cells were identified as C16:0, C16:1ω7c and C18:1ω7c. The predominant respiratory quinone was found to be ubiquinone-Q10. The G+C content of genomic DNA for strain H5569(T) was found to be 49.9 %. Based on 16S rRNA gene sequence analysis results, 13 a...
Source: Antonie van Leeuwenhoek - February 8, 2016 Category: Microbiology Authors: Humrighouse BW, Emery BD, Kelly AJ, Metcalfe MG, Mbizo J, McQuiston JR Tags: Antonie Van Leeuwenhoek Source Type: research

Altererythrobacter estronivorus sp. nov., an Estrogen-Degrading Strain Isolated from Yundang Lagoon of Xiamen City in China.
Abstract A novel gram-negative, non-spore-forming, mobile, estrogen-degrading strain, MH-B5(T), was isolated from Yundang Lagoon in Xiamen city of China. Growth of this strain occurred between 4 and 40 °C (optimum at 35 °C), pH 5.5-10.0 (7.5), 0.0-7 % NaCl (1-2 %). Phylogenetic analysis based on 16S rRNA gene sequence showed that strain MH-B5(T) belonged to the genus Altererythrobacter family Erythrobacteraceae, showing the highest sequence similarity (96.6 %) to Altererythrobacter xinjiangensis S3-63(T). The dominant cellular fatty acid was C18:1 ω7c and/or C18:1 ω6c (57.98 %). The major respiratory quin...
Source: Current Microbiology - February 8, 2016 Category: Microbiology Authors: Qin D, Ma C, Hu A, Zhang F, Hu H, Yu CP Tags: Curr Microbiol Source Type: research

The home environment of junior high school students in Hyogo, Japan - Associations with asthma, respiratory health and reported allergies
In conclusion, in Japanese homes, the window condensation in winter, recent indoor painting and living in a wooden house could contribute to the increased risk of respiratory symptoms and allergies for young Japanese school children. (Source: Indoor and Built Environment)
Source: Indoor and Built Environment - February 8, 2016 Category: Occupational Health Authors: Takaoka, M., Suzuki, K., Norbäck, D. Tags: Original Papers Source Type: research

Respiratory dysfunction in patients with chronic neck pain: what is the current evidence?
Respiratory function of patients with neck pain has not been given much consideration in usual clinical practice. The problem has however been highlighted occasionally by renown clinical scientists and recently there is a growing interest in the investigation of respiratory function in this clinical population. The aim of this review is to critically present the emerging evidence and discuss the similarities and differences observed. Although the evidence for some respiratory parameters is conflicting, it seems to be generally agreed that others such as maximal voluntary ventilation, strength of respiratory muscles, chest ...
Source: Journal of Bodywork and Movement Therapies - February 8, 2016 Category: Physiotherapy Authors: Zacharias Dimitriadis, Eleni Kapreli, Nikolaos Strimpakos, Jacqueline Oldham Source Type: research