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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 4.

Association between XPA Gene rs1800975 Polymorphism and Susceptibility to Lung Cancer: A meta ‐analysis
Conclusions: This meta‐analysis suggested that the XPA gene rs1800975 Polymorphism was associated with lung cancer susceptibility. By performing multiple separate pairwise comparisons, carriers with AG genotype under the codominant genetic model(AG vs. AA) might play actually the leading role in associating with lung cancer susceptibility in overall and in Asians. This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - July 27, 2016 Category: Respiratory Medicine Authors: Xin Liu, Qunying Lin, Cuiping Fu, Chengying Liu, Fen Zhu, Zilong Liu, Shanqun Li, Liyan Jiang Tags: Original Article Source Type: research

Self ‐reported reasons for treatment non‐adherence in Chinese asthma patients: A 24‐week prospective telephone follow‐up study
ConclusionsAsthma patients' treatment adherence could be improved by improving patient education, doctor/patient partnership, and level of medical service in Chinese population. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - July 27, 2016 Category: Respiratory Medicine Authors: Qianli Ma, Guangming Luo, Xiangdong Zhou, Ying Huang, Enmei Liu, Xin Hong, Liangping Mao, Yamei Wu, Xumei Chen, Xiuqing Liao, Guangmei Qin, Daoxin Wang, Lian Li, Shifu Zhang, Changzheng Wang Tags: Original Article Source Type: research

Brainstem-mediated sniffing and respiratory modulation during odor stimulation.
In conclusion, we show for the first time the direct involvement of brainstem circuits in primary odor processing to evoke protective sniffs and respiratory modulation in the complete absence of forebrain commands. (Source: Respiratory Physiology and Neurobiology)
Source: Respiratory Physiology and Neurobiology - July 27, 2016 Category: Respiratory Medicine Source Type: research

Ask-Upmark kidney with bilateral pelvi-ureteric junction obstruction – A rare entity
We report a case of two years’ male child presenting as abdominal swelling with respiratory distress. On evaluation he was found to have bilateral pelvi-ureteric junction obstruction and left non-functioning kidney for which he underwent right pyeloplasty and left nephrectomy later on. Histopathology report of left kidney suggestive of segmental renal hypoplasia (Ask-Upmark kidney). (Source: African Journal of Urology)
Source: African Journal of Urology - July 27, 2016 Category: Urology & Nephrology Source Type: research

Molecules, Vol. 21, Pages 975: Corynoline Isolated from Corydalis bungeana Turcz. Exhibits Anti-Inflammatory Effects via Modulation of Nfr2 and MAPKs
In this study, we investigated the potential anti-inflammatory mechanism of corynoline through modulation of Nfr2 and MAPKs. Lipopolysaccharide (LPS)-activated RAW264.7 cells were used to explore modulatory role of NO production and the activation of signaling proteins and transcription factors using nitrite assay, Western bloting and qPCR. Treatment with corynoline reduced production of nitric oxide (NO) and the protein and mRNA levels of inducible nitric oxide (iNOS) and cyclooxygenase-2 (COX-2) Treatment also significantly increased the expression of Nrf2, quinone oxidoreductase 1 (NQO1) and hemeoxygenase-1 (HO-1) at th...
Source: Molecules - July 27, 2016 Category: Chemistry Authors: Chunjuan Yang Chengyue Zhang Zhibin Wang Zhenqiu Tang Haixue Kuang Ah-Ng Kong Tags: Article Source Type: research

Molecules, Vol. 21, Pages 974: Structure-Bioactivity Relationships of Methylxanthines: Trying to Make Sense of All the Promises and the Drawbacks
Methylxanthines are a group of phytochemicals derived from the purine base xanthine and obtained from plant secondary metabolism. They are unobtrusively included in daily diet in common products as coffee, tea, energetic drinks, or chocolate. Caffeine is by far the most studied methylxanthine either in animal or epidemiologic studies. Theophylline and theobromine are other relevant methylxanthines also commonly available in the aforementioned sources. There are many disseminated myths about methylxanthines but there is increased scientific knowledge to discuss all the controversy and promise shown by these intriguing phyto...
Source: Molecules - July 27, 2016 Category: Chemistry Authors: Jo ão Monteiro Marco Alves Pedro Oliveira Branca Silva Tags: Review Source Type: research

Lichen secondary metabolite evernic acid as potential quorum sensing inhibitor against Pseudomonas aeruginosa
This study aims to investigate an alternative treatment approach by utilizing lichen secondary metabolite evernic acid to reduce the expressions of < em class= " a-plus-plus " > Pseudomonas < /em > < em class= " a-plus-plus " > aeruginosa < /em > virulence factors by inhibiting quorum sensing. For this purpose, fluorescent monitor strains were utilized for quorum sensing inhibitor screens and quantitative reverse-transcriptase PCR analyses were conducted for comparison. Results indicate that evernic acid is capable of inhibiting < em class= " a-plus-plus " > Pseudomonas < /em > < em class= " a-plus-plus " > aeruginosa < /e...
Source: World Journal of Microbiology and Biotechnology - July 27, 2016 Category: Microbiology Source Type: research

NT ‐proBNP and cardiac troponin I concentrations in dogs with tick paralysis caused by Ixodes holocyclus
ConclusionThis study did not detect significant cardiac involvement in dogs with tick paralysis induced by I. holocyclus. Evidence for reduced preload in dogs with tick paralysis was provided by lower NT‐proBNP concentrations compared with control dogs. Severe hypoxaemia may not be a significant component of the clinical picture in many of the dogs presenting with tick paralysis. Dogs with severe hypoxaemia may have loss of cardiomyocyte integrity, reflected by elevated cTnI concentrations. (Source: Australian Veterinary Journal)
Source: Australian Veterinary Journal - July 27, 2016 Category: Veterinary Research Authors: GP Nicolson, ALH McGrath, RA Webster, J Li, S Kaye, R Malik, NJ Beijerink Tags: SMALL ANIMALS Source Type: research

Plasmodium infection in a Leadbeater's possum (Gymnobelideus leadbeateri)
ConclusionThis is the first report of Plasmodium sp. infection and subsequent disease in a native Australian mammal. The lifecycle of this parasite remains unknown. It is also unknown what effects haemoparasitism may have on the population dynamics of this endangered possum species. (Source: Australian Veterinary Journal)
Source: Australian Veterinary Journal - July 27, 2016 Category: Veterinary Research Authors: TF Scheelings, PJ McLaren, L Tatarczuch, RF Slocombe Tags: CASE REPORT Source Type: research

Observations on macrolide resistance and susceptibility testing performance in field isolates collected from clinical bovine respiratory disease cases
The objectives of this study were; first, to describe gamithromycin susceptibility of Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni isolated from cattle diagnosed with bovine respiratory disease (BRD) and previously treated with either gamithromycin for control of BRD (mass medication=MM) or sham-saline injected (control=CON); second, to describe the macrolide resistance genes present in genetically typed M. haemolytica isolates; third, use whole-genome sequencing (WGS) to correlate the phenotypic resistance and genetic determinants for resistance among M. haemolytica isolates. M. haemolytica (n=276)...
Source: Veterinary Microbiology - July 27, 2016 Category: Veterinary Research Source Type: research

Acute myocarditis in bodybuilder from coxsackievirus and thyrotoxicosis
Publication date: Available online 20 July 2016 Source:Journal of Cardiology Cases Author(s): Tommy Kwak, Moamen Al Zoubi, Aruni Bhavith, Carlos Rueda Rios, Surender Kumar A 25-year-old male with no past medical history presented with 1 day of chest pain. The patient had exercised with high intensity for a bodybuilding competition. He had fever, malaise, sore throat, and cough 1 week before presentation. He was tachycardic and tachypneic. Cardiac examination was unremarkable. Electrocardiogram showed diffuse ST segment elevation. Laboratory results showed leukocytosis, creatinine kinase 3078unit/L, and troponin I 78...
Source: Journal of Cardiology Cases - July 27, 2016 Category: Cardiology Source Type: research

Anti-Respiratory Syncytial Virus Compounds from Two Endophytic Fungi Isolated from Nigerian Medicinal Plants
Conclusion: The results of the present study have shown that chloroisosulochrin (5), isolated from an endophytic fungus P. thea, possesses strong activity against RSV.[...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: Drug Research)
Source: Drug Research - July 27, 2016 Category: Drugs & Pharmacology Authors: Uzor, P. F. Odimegwu, D. C. Ebrahim, W. Osadebe, P. O. Nwodo, N. J. Okoye, F. B. C. Liu, Z. Proksch, P. Tags: Original Article Source Type: research

Suboptimal CT pulmonary angiography in the emergency department: a retrospective analysis of outcomes in a large academic medical center
In this study, we analyze the incidence and cause of suboptimal CTPA studies in the ED and assess the need for additional imaging. Reports of 1444 consecutive CTPAs performed in an ED on adult patients over a 25-month period beginning November 30, 2011, were reviewed. The observed suboptimal CTPA rate was 4.2  % (60/1444). The most common causes of limited or non-diagnostic CTPA in the ED were related to timing of contrast bolus or IV infiltration (26/60, 43.4 %), respiratory motion (16/60, 26.7 %), multifactorial causes (10/60, 16.7 %), and patient motion (8/60, 13.3 %). Of the 60 studies included, only 7 patients (1...
Source: Emergency Radiology - July 27, 2016 Category: Emergency Medicine Source Type: research

Acute Gastric Volvulus in the Elderly: A Case Report and Review of the Literature
We present a case of gastric volvulus in a 91-year-old woman. The patient presented with abdominal pain, recurrent episodes of hematemesis, acute respiratory failure, and severe hypotension. The diagnosis of gastric volvulus was suspected by esophagogastroduodenoscopy, and confirmed later by both esophageal and upper gastrointestinal contrast study and abdominal computed tomography. Management consisted of intubation and mechanical ventilation, fluid loading and transfusion, vasopressor infusion, and surgical reduction of the volvulus. (Source: International Journal of Gerontology)
Source: International Journal of Gerontology - July 27, 2016 Category: Geriatrics Source Type: research

Carbapenemase-producing Klebsiella pneumoniae in broiler poultry farming in Egypt
This study investigated the occurrence of carbapenem-resistant Klebsiella pneumoniae strains in broiler chickens, drinking water and humans working in contact with chickens and identified the carbapenem resistance determinants among isolates from different sources. Internal organs and droppings were collected from 100 broilers with signs of respiratory disease at five broiler farms in Egypt. Additionally, 20 drinking water samples and 49 faecal samples from workers and veterinarians working at these farms were included. Following culture on MacConkey agar, suspected K. pneumoniae colonies were identified by phenotypic test...
Source: Journal of Global Antimicrobial Resistance - July 27, 2016 Category: Infectious Diseases Source Type: research

Using Technology to Affect Influenza Vaccine Coverage Among Children With Chronic Respiratory Conditions
Influenza presents additional burdens for children with chronic respiratory conditions. Influenza vaccinations may reduce complications, yet approximately half of children remain unprotected. Evidence supports integration of text and e-mail into multicomponent strategies to increase influenza vaccination rates among children with chronic respiratory conditions. (Source: Journal of Pediatric Health Care)
Source: Journal of Pediatric Health Care - July 27, 2016 Category: Pediatrics Authors: Sarah L. Bay, Daniel J. Crawford Tags: Article Source Type: research

A novel excitatory network for the control of breathing
Nature advance online publication 27 July 2016. doi:10.1038/nature18944 Authors: Tatiana M. Anderson, Alfredo J. Garcia, Nathan A. Baertsch, Julia Pollak, Jacob C. Bloom, Aguan D. Wei, Karan G. Rai & Jan-Marino Ramirez Breathing must be tightly coordinated with other behaviours such as vocalization, swallowing, and coughing. These behaviours occur after inspiration, during a respiratory phase termed postinspiration. Failure to coordinate postinspiration with inspiration can result in aspiration pneumonia, the leading cause of death in Alzheimer’s disease, Parkinson’s disease, dementia, and other neurodegenerative ...
Source: Nature AOP - July 27, 2016 Category: Research Authors: Tatiana M. Anderson Alfredo J. Garcia Nathan A. Baertsch Julia Pollak Jacob C. Bloom Aguan D. Wei Karan G. Rai Jan-Marino Ramirez Tags: Letter Source Type: research

Immunoglobulin G response to mammalian cell entry 1A (Mce1A) protein as biomarker of active tuberculosis
Cell wall components are major determinants of virulence of Mycobacterium tuberculosis and they contribute to the induction of both humoral and cell-mediated immune response. The mammalian cell entry protein 1A (Mce1A), in the cell wall of M. tuberculosis, mediates entry of the pathogen into mammalian cells. Here, we examined serum immunoglobulin levels (IgA, IgM and total IgG) against Mce1A as a potential biomarker for diagnosis and monitoring tuberculosis (TB) treatment response. Serum samples of 39 pulmonary TB patients and 65 controls (15 healthy household contacts, 19 latently infected household contacts, 13 non-TB an...
Source: Tuberculosis - July 27, 2016 Category: Respiratory Medicine Authors: Iukary Takenami, Carolina C. de Oliveira, Filipe R. Lima, J éssica Soares, Almério de S. Machado, Lee W. Riley, Sérgio Arruda Tags: Diagnostics Source Type: research

Ivacaftor and symptoms of extra-oesophageal reflux in patients with cystic fibrosis and G551D mutation
Extra-oesophageal reflux (EOR) may lead to microaspiration in patients with cystic fibrosis (CF), a probable cause of deteriorating lung function. Successful clinical trials of ivacaftor highlight opportunities to understand EOR in a real world study. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - July 27, 2016 Category: Respiratory Medicine Authors: Gemma L. Zeybel, Jeffrey P. Pearson, Amaran Krishnan, Stephen J. Bourke, Simon Doe, Alan Anderson, Shoaib Faruqi, Alyn H. Morice, Rhys Jones, Melissa McDonnell, Mujdat Zeybel, Peter W. Dettmar, Malcolm Brodlie, Chris Ward Tags: Original Article Source Type: research

Paravertebral pseudotumor in patient with hereditary spherocytosis
Publication date: Available online 27 July 2016 Source:Respiratory Medicine Case Reports Author(s): Lêda Maria Rabelo, Vítor Lopes Galvão Vieira, Gustavo Rengel dos Santos, Giselle Heimbecker, Dante Luiz Escuissato As a rare complication in chronic anemic states, the extramedullary hematopoiesis may provide diagnostic and therapeutic challenge. Caused by the insufficiency of the bone marrow with reactivation of quiescent erythropoietic sites, this condition may vary its presentation as a simples radiologic finding to a spontaneous massive haemothorax. In this paper, we report the case of a 61-years-old female pat...
Source: Respiratory Medicine Case Reports - July 27, 2016 Category: Respiratory Medicine Source Type: research

Sedation quality in intensive care: which interventions work?
Publication date: Available online 26 July 2016 Source:The Lancet Respiratory Medicine Author(s): Richard R Riker, Gilles L Fraser (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - July 27, 2016 Category: Respiratory Medicine Source Type: research

Staff education, regular sedation and analgesia quality feedback, and a sedation monitoring technology for improving sedation and analgesia quality for critically ill, mechanically ventilated patients: a cluster randomised trial
Publication date: Available online 26 July 2016 Source:The Lancet Respiratory Medicine Author(s): Timothy S Walsh, Kalliopi Kydonaki, Jean Antonelli, Jacqueline Stephen, Robert J Lee, Kirsty Everingham, Janet Hanley, Emma C Phillips, Kimmo Uutela, Petra Peltola, Stephen Cole, Tara Quasim, James Ruddy, Marcia McDougall, Alan Davidson, John Rutherford, Jonathan Richards, Christopher J Weir Background Optimal sedation of patients in intensive care units (ICUs) requires the avoidance of pain, agitation, and unnecessary deep sedation, but these outcomes are challenging to achieve. Excessive sedation can prol...
Source: The Lancet Respiratory Medicine - July 27, 2016 Category: Respiratory Medicine Source Type: research

Myopathies in the adult patient
About 70,000 people in the UK (around 62 million) have a peripheral neuromuscular disorder, with about one-half of them having a myopathy. They can be acquired or inherited. Most of the former respond to removal of the cause or specific treatment, whereas most of the latter have no specific treatment. Much can be done to improve quality of life and reduce morbidity and mortality in hereditary myopathies, particularly relating to cardiac and respiratory management. Precise molecular diagnosis is essential for accurate genetic counselling and the provision of reproductive options. (Source: Medicine)
Source: Medicine - July 27, 2016 Category: Internal Medicine Authors: David Hilton-Jones Tags: Spinal cord, nerve, muscle Source Type: research

Maternal Super Obesity and Neonatal Morbidity after Term Cesarean Delivery
Conclusion Among term infants delivered via CD, maternal super obesity is associated with increased risk of neonatal morbidity.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - July 27, 2016 Category: Perinatology & Neonatology Authors: Smid, Marcela C. Vladutiu, Catherine J. Dotters-Katz, Sarah K. Manuck, Tracy A. Boggess, Kim A. Stamilio, David M. Tags: 2016 SMFM Annual Meeting Source Type: research

A molecular epidemiological study of human parainfluenza virus type 3 at a tertiary university hospital during 2013 –2015 in Catalonia, Spain
Human parainfluenza virus type 3 (HPIV-3) is one of the most common respiratory viruses particularly among young children and immunocompromised patients. The seasonality, prevalence and genetic diversity of HPIV-3 at a Spanish tertiary-hospital from 2013 to 2015 are reported. HPIV-3 infection was laboratory-confirmed in 102 patients (76%, under 5years of age). Among < 5years-old patients, 9 (11.5%) were under any degree of immunosuppression, whereas this percentage was significantly higher (19; 79.2%) among patients older than 5years of age. (Source: Diagnostic Microbiology and Infectious Disease)
Source: Diagnostic Microbiology and Infectious Disease - July 27, 2016 Category: Microbiology Authors: Cristina Godoy, Paula Peremiquel, Cristina Andr és, Laura Gimferrer, Sonia María Uriona, Maria Gemma Codina, Lluis Armadans, María del Carmen Martín, Francisco Fuentes, Juliana Esperalba, Magda Campins, Tomàs Pumarola, Andrés Antón Source Type: research

Bacterial microbiota of the upper respiratory tract and childhood asthma
The bacterial nasal microbiota is altered in children with asthma. Research into the interplay between microbes, the human body and the environment may open new horizons in asthma prevention and treatment. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - July 27, 2016 Category: Allergy & Immunology Authors: Martin Depner, Markus J. Ege, Michael J. Cox, Sarah Dwyer, Alan W. Walker, Lena T. Birzele, Jon Genuneit, Elisabeth Horak, Charlotte Braun-Fahrl änder, Hanna Danielewicz, Raina M. Maier, Miriam F. Moffat, William O. Cookson, Dick Heederik, Erika von Muti Source Type: research

Micrococcin P1 - A bactericidal thiopeptide active against Mycobacterium tuberculosis
The lack of proper treatment for serious infectious diseases due to the emergence of multidrug resistance (MDR) reinforces the need for the discovery of novel antibiotics. This is particularly true for tuberculosis (TB) for which 3.7% of new cases and 20% of previously treated cases are estimated to be caused by MDR-TB. In addition, in the case of TB, which claimed 1.5 million lives in 2014, the treatment of the least complicated, drug sensitive cases is lengthy and disagreeable. Therefore, new drugs with novel targets are urgently needed to control resistant Mycobacterium tuberculosis strains. (Source: Tuberculosis)
Source: Tuberculosis - July 27, 2016 Category: Respiratory Medicine Authors: Giulia Degiacomi, Yoann Personne, Guillaume Mond ésert, Xueliang Ge, Chandra Sekhar Mandava, Ruben C. Hartkoorn, Francesca Boldrin, Pavitra Goel, Kristin Peisker, Andrej Benjak, Maria Belén Barrio, Marcello Ventura, Amanda C. Brown, Véronique Leblanc, Tags: Drug Discovery and Resistance Source Type: research

Predictors of idiopathic pulmonary fibrosis in absence of radiologic honeycombing: A cross sectional analysis in ILD patients undergoing lung tissue sampling
Idiopathic pulmonary fibrosis (IPF) can be diagnosed confidently and non-invasively when clinical and computed tomography (CT) criteria are met. Many do not meet these criteria due to absence of CT honeycombing. We investigated predictors of IPF and combinations allowing accurate diagnosis in individuals without honeycombing. (Source: Respiratory Medicine)
Source: Respiratory Medicine - July 27, 2016 Category: Respiratory Medicine Authors: Margaret L. Salisbury, Meng Xia, Susan Murray, Brian J. Bartholmai, Ella A. Kazerooni, Catherine A. Meldrum, Fernando J. Martinez, Kevin R. Flaherty Source Type: research

Critical care admission trends and outcomes in individuals with bronchiectasis in the UK
Conclusion: Admission to ICU in people with bronchiectasis are uncommon, but are increasing in frequency over time, and carries a substantial mortality rate. This needs to be considered allocating health care resources and planning respiratory services. (Source: QJM)
Source: QJM - July 27, 2016 Category: Internal Medicine Authors: Navaratnam, V., Muirhead, C. R., Hubbard, R. B., De Soyza, A. Tags: Original papers Source Type: research

TP53-dependent autophagy links the ATR-CHEK1 axis activation to proinflammatory VEGFA production in human bronchial epithelial cells exposed to fine particulate matter (PM2.5).
Abstract Epidemiological and clinical studies have increasingly shown that fine particulate matter (PM2.5) is associated with a number of pathological respiratory diseases, such as bronchitis, asthma and chronic obstructive pulmonary disease, which share the common feature of airway inflammation induced by particle exposure. Thus, understanding how PM2.5 triggers inflammatory responses in the respiratory system is crucial for the study of PM2.5 toxicity. In the current study, we found that exposing human bronchial epithelial cells (immortalized Beas-2B cells and primary cells) to PM2.5 collected in the winter in Wu...
Source: Autophagy - July 27, 2016 Category: Cytology Authors: Xu X, Wang H, Liu S, Xing C, Liu Y, Qimuge A, Zhou W, Yuan X, Ma Y, Hu M, Hu Y, Zou S, Gu Y, Peng S, Yuan S, Li W, Ma Y, Song L Tags: Autophagy Source Type: research

Giant Pulmonary Hydatid Cyst: An Unusual Presentation.
PMID: 27463380 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - July 27, 2016 Category: Respiratory Medicine Authors: Sharma P, Kumar N, Jain A, Raghav N Tags: Am J Respir Crit Care Med Source Type: research

The 2016 Guidelines for Hospital-Acquired and Ventilator-Associated Pneumonia: A Selection Correction?
PMID: 27463241 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - July 27, 2016 Category: Respiratory Medicine Authors: Govindan S, Hyzy RC Tags: Am J Respir Crit Care Med Source Type: research

"Radiologic CT features of Mycobacterium abscessus in Cystic Fibrosis".
CONCLUSION: The most common CT features of early M. abscessus in our CF population include bronchiectasis, mucus plugging, and consolidation, but the findings did not reveal a unique radiologic signature. CT at this initial time point may not distinguish early M. abscessus infection from background lung disease or mycobacterial colonization in CF patients. This article is protected by copyright. All rights reserved. PMID: 27460837 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - July 27, 2016 Category: Respiratory Medicine Authors: Lam DL, Kapnadak SG, Godwin JD, Kicska GA, Aitken ML, Pipavath SN Tags: Clin Respir J Source Type: research

Maternal Responses to Aerobic Exercise in Pregnancy
Exercise is one of the most physiologically challenging stressors requiring the coordination of metabolic, respiratory, and cardiovascular responses to meet increased energy requirements of the working muscle. During pregnancy, all women without contraindication are encouraged to exercise as part of a healthy lifestyle. Pregnancy itself is associated with profound physiological adaptations to the maternal cardiovascular, respiratory, and metabolic systems, which serve to support the needs of the growing fetus. Therefore the physiological adaptations to exercise during pregnancy are more pronounced and critically important....
Source: Clinical Obstetrics and Gynecology - July 26, 2016 Category: OBGYN Tags: Clinical Updates in Women's Health Care Source Type: research

Reversal of Dabigatran in a Patient with ACS and Recurrent Pulmonary Oedema
History: A 68 year old male was admitted to respiratory with fever and worsening SOB. Diagnosis was chest infection in a heavy smoker with noted intermittent atrial fibrillation without angina but very elevated troponin. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 26, 2016 Category: Cardiology Authors: D. Colquhoun Tags: 43 Source Type: research

A Case Presentation of Peripartum Cardiomyopathy with Multiple Complications and Associated Treatment Dilemmas
27 year old female presented to hospital with gradually increasing dyspnoea for 3 days with palpitations and cough. Background: 35/40 gestation, G2P1, Diabetes Insipidus, Morbid obesity (BMI 48). Treated empirically for pulmonary embolus with enoxaparin and covered with antibiotics for pneumonia, and admitted to women's health ward. Deteriorated later that night with respiratory distress. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 26, 2016 Category: Cardiology Authors: E. Nehme, J. Riskallah, D. Burgess, A. Kanthan Tags: 222 Source Type: research

Triggering of Acute Myocardial Infarction by Respiratory Infection
Background: Evidence suggests that pneumonia, bronchitis and influenza are associated with increased short-term risks of myocardial infarction (MI). However, this has not yet been convincingly shown in studies of angiographically confirmed MI, which are able to exclude the possibility of raised troponin and electrocardiogram changes due to other causes such as myocarditis. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 26, 2016 Category: Cardiology Authors: L. Ruane, T. Buckley, S. Soo Hoo, P. Hansen, C. McCormac, E. Shaw, G. Tofler Tags: 159 Source Type: research

Five Years of Sustained Success. Small Changes Can Make Huge Difference in Pneumothorax Prevention
Background: Pneumothoraces can cause respiratory distress, extended hospitalisation, and reduced patient satisfaction and potentially causing harm. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 26, 2016 Category: Cardiology Authors: M. Habibian, R. Batra, H. Gunter, G. Aroney, A. Sweeny, V. Kapadia, N. Essack, A. Rahman Tags: 343 Source Type: research

HACEK Endocarditis Presenting With Atrioventricular Conduction Abnormality
We present the case of a 72-year-old man who was admitted to a district hospital with a 3-week history of pyrexia of unknown origin. This was on the background of a previously documented systolic murmur. No source of sepsis was identified, but he was commenced on IV antibiotics empirically for a presumed lower respiratory tract infection. On day 3 of his admission, he developed acute monocular visual loss. Ophthalmology review identified a central retinal artery occlusion with central sparing, consistent with embolic phenomenon. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 26, 2016 Category: Cardiology Authors: U. Allahwala, D. Marshman, G. Tofler Tags: 542 Source Type: research