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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 4.

Rescue therapy using an endobronchial valve and digital air leak monitoring in Invasive Pulmonary Aspergillosis
We report the case of a young leukaemic woman with a PAL complicating Invasive Pulmonary Aspergillosis (IPA), who was effectively managed using an Endobronchial Valve, supplemented by objective, digital air-leak data provided by a Thopaz® device (Medela, Switzerland). (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - December 17, 2014 Category: Respiratory Medicine Source Type: research

Co-Infection of long standing Extensively Drug-Resistant Mycobacterium tuberculosis (XDR-TB) and Non-tuberculosis Mycobacteria: A Case Report
We report a 69-years-old Iranian HIV negative male patient, with long-standing pulmonary tuberculosis (eleven years) co-infected with non-tuberculosis Mycobacteria. Despite of initiation of first line anti-tuberculosis therapy after diagnosis the patient poorly respond because of low compliance with anti-TB treatment. After several incomplete treatments the smear was still positive and thus drug susceptibility tests were performed on isolated organism which revealed that the organisms was resistant not only against isoniazid and rifampin but also against Ofloxacin(OFX), Capreomycin(CAP), p-aminosalicylic acid(PAS), ethiona...
Source: Respiratory Medicine Case Reports - December 17, 2014 Category: Respiratory Medicine Source Type: research

Tracheal epithelial-myoepithelial carcinoma associated with sarcoid-like reaction: a case report
We report the first case of epithelial-myoepithelial carcinoma associated with sarcoidosis. A 61 year old Hispanic man presented with altered mental status and hypercalcemia. Imaging revealed diffuse intra-thoracic and intra-abdominal lymphadenopathy. A diagnostic bronchoscopy was performed where an incidental tracheal nodule was discovered and biopsied. Pathology was consistent with epithelial-myoepithelial carcinoma. Lymph node biopsy demonstrated non-caseating granulomas consistent with sarcoidosis. Patient underwent tracheal resection of the primary tumor with primary tracheal reconstruction. Hypercalcemia subsequently...
Source: Respiratory Medicine Case Reports - December 17, 2014 Category: Respiratory Medicine Source Type: research

Cell therapies for ARDS: a promising start
Publication date: Available online 17 December 2014 Source:The Lancet Respiratory Medicine Author(s): Daniel J Weiss (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - December 17, 2014 Category: Respiratory Medicine Source Type: research

Sexual and reproductive health in cystic fibrosis: a life-course perspective
Publication date: Available online 17 December 2014 Source:The Lancet Respiratory Medicine Author(s): Katherine B Frayman , Susan M Sawyer Adolescents and adults with cystic fibrosis now approach developmental milestones, including sexual and reproductive ones, at a similar time to their healthy peers. Yet, their sexual and reproductive health (SRH) is profoundly affected by their disease, and their SRH decisions can substantially affect their health. Navigation of SRH milestones in the context of cystic fibrosis needs education, guidance, and access to SRH services. In this Review, we discuss scientific knowledge of SRH...
Source: The Lancet Respiratory Medicine - December 17, 2014 Category: Respiratory Medicine Source Type: research

Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial
Publication date: Available online 17 December 2014 Source:The Lancet Respiratory Medicine Author(s): Jennifer G Wilson , Kathleen D Liu , Hanjing Zhuo , Lizette Caballero , Melanie McMillan , Xiaohui Fang , Katherine Cosgrove , Rosemary Vojnik , Carolyn S Calfee , Jae-Woo Lee , Angela J Rogers , Joseph Levitt , Jeanine Wiener-Kronish , Ednan K Bajwa , Andrew Leavitt , David McKenna , B Taylor Thompson , Michael A Matthay Background No effective pharmacotherapy for acute respiratory distress syndrome (ARDS) exists, and mortality remains high. Preclinical studies support the efficacy of mesenchymal stem (stromal) cells (M...
Source: The Lancet Respiratory Medicine - December 17, 2014 Category: Respiratory Medicine Source Type: research

The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis
Conclusion. The addition of tacrolimus to conventional therapy significantly improved the prognosis of patients with PM-/DM-related ILD. (Source: Rheumatology)
Source: Rheumatology - December 17, 2014 Category: Rheumatology Authors: Kurita, T., Yasuda, S., Oba, K., Odani, T., Kono, M., Otomo, K., Fujieda, Y., Oku, K., Bohgaki, T., Amengual, O., Horita, T., Atsumi, T. Tags: Myositis and Muscle Disease CLINICAL SCIENCE Source Type: research

Transcathater percutaneous device closure of largest PDA closed in a 3 kg infant
Publication date: Available online 16 December 2014 Source:Indian Heart Journal Author(s): N.O. Bansal , Sandesh Prabhu , Dhananjay Ware , Sanjaykumar K. Shivapuje Patent ductus arteriosus (PDA) is common congenital heart disease which may require treatment as transcatheter percutaneous device closure (PDA device closure) or surgical ligation in symptomatic full-term patients. Surgical ligation is an invasive procedure and has more complications especially in the neonates. Problems in PDA device closure are difficult vascular access, manipulation of catheters and sheath, residual shunts, residual obstruction of major art...
Source: Indian Heart Journal - December 17, 2014 Category: Cardiology Source Type: research

Comparison of Texture Features Derived from Static and Respiratory-Gated PET Images in Non-Small Cell Lung Cancer
by Stephen Yip, Keisha McCall, Michalis Aristophanous, Aileen B. Chen, Hugo J. W. L. Aerts, Ross Berbeco Background PET-based texture features have been used to quantify tumor heterogeneity due to their predictive power in treatment outcome. We investigated the sensitivity of texture features to tumor motion by comparing static (3D) and respiratory-gated (4D) PET imaging. Methods Twenty-six patients (34 lesions) received 3D and 4D [18F]FDG-PET scans before the chemo-radiotherapy. The acquired 4D data were retrospectively binned into five breathing phases to create the 4D image sequence. Texture features, including Maximal ...
Source: PLoS One - December 17, 2014 Category: Biomedical Science Authors: Stephen Yip et al. Source Type: research

Olfactory airflow in bat nasal cavities
The morphology of the nasal cavity in mammals with a good sense of smell includes features that are thought to improve olfactory airflow, such as a dorsal conduit that delivers odours quickly to the olfactory mucosa, an enlarged olfactory recess at the back of the airway, and a clear separation of the olfactory and respiratory regions of the nose. The link between these features and having a good sense of smell has been established by functional examinations of a handful of distantly related mammalian species. In this paper, we provide the first detailed examination of olfactory airflow in a group of closely related specie...
Source: Proceedings of the Royal Society B: Biological Sciences - December 17, 2014 Category: Biology Authors: Eiting, T. P., Perot, J. B., Dumont, E. R. Tags: biomechanics, evolution Research articles Source Type: research

Anaemia only causes a small reduction in the upper critical temperature of sea bass: is oxygen delivery the limiting factor for tolerance of acute warming in fishes? [SHORT COMMUNICATIONS]
Tobias Wang, Sjannie Lefevre, Nina K. Iversen, Inge Findorf, Rasmus Buchanan, and David J. McKenzie To address how the capacity for oxygen transport influences tolerance of acute warming in fishes, we investigated whether a reduction in haematocrit, by means of intra-peritoneal injection of the haemolytic agent phenylhydrazine, lowered the upper critical temperature of sea bass. A reduction in haematocrit from 42±2% to 20±3% (mean ± s.e.m.) caused a significant but minor reduction in upper critical temperature, from 35.8±0.1 to 35.1±0.2°C, with no correlation between individual values...
Source: Journal of Experimental Biology - December 17, 2014 Category: Biology Authors: Wang, T., Lefevre, S., Iversen, N. K., Findorf, I., Buchanan, R., McKenzie, D. J. Tags: SHORT COMMUNICATIONS Source Type: research

Air breathing in the Arctic: influence of temperature, hypoxia, activity and restricted air access on respiratory physiology of the Alaska blackfish Dallia pectoralis [RESEARCH ARTICLES]
Sjannie Lefevre, Christian Damsgaard, Desirae R. Pascale, Goran E. Nilsson, and Jonathan A. W. Stecyk The Alaska blackfish (Dallia pectoralis) is an air-breathing fish native to Alaska and the Bering Sea islands, where it inhabits lakes that are ice-covered in the winter, but enters warm and hypoxic waters in the summer to forage and reproduce. To understand the respiratory physiology of this species under these conditions and the selective pressures that maintain the ability to breathe air, we acclimated fish to 5°C and 15°C and used respirometry to measure: standard oxygen uptake ( ) in normoxia (19.8 kPa PO2) an...
Source: Journal of Experimental Biology - December 17, 2014 Category: Biology Authors: Lefevre, S., Damsgaard, C., Pascale, D. R., Nilsson, G. E., Stecyk, J. A. W. Tags: RESEARCH ARTICLES Source Type: research

Metabolism and water loss rate of the haematophagous insect Rhodnius prolixus: effect of starvation and temperature [RESEARCH ARTICLES]
Carmen Rolandi, Monica S. Iglesias, and Pablo E. Schilman Haematophagous insects suffer big changes in water needs under different levels of starvation. Rhodnius prolixus is the most important haematophagous vector of Chagas disease in the north of South America and a model organism in insect physiology. Although there have been some studies on patterns of gas exchange and metabolic rates, there is little information regarding water loss in R. prolixus. We investigated whether there is any modulation of water loss and metabolic rate under different requirements for saving water. We measured simultaneously CO2 production, w...
Source: Journal of Experimental Biology - December 17, 2014 Category: Biology Authors: Rolandi, C., Iglesias, M. S., Schilman, P. E. Tags: RESEARCH ARTICLES Source Type: research

Nontraumatic Fat Embolism Found Following Maternal Death after Cesarean Delivery
We present the first case of maternal death that resulted from nontraumatic fat embolization following Cesarean delivery. Case Description A 29-year-old gravida 1 with a complex medical and surgical history underwent a primary Cesarean delivery at term. On postoperative day 2 the patient was found to be unresponsive. Despite resuscitative efforts, the patient succumbed. Autopsy findings were remarkable for diffuse pulmonary fat emboli. Furthermore, there was no histological evidence of either amniotic fluid embolism or thromboembolism. The primary cause of death was attributed to nontraumatic fat embolization. ...
Source: American Journal of Perinatology Reports - December 17, 2014 Category: Perinatology & Neonatology Authors: Schrufer-Poland, TabithaSingh, PaulJodicke, CristianoReynolds, SaraMaulik, Dev Tags: Case Report Source Type: research

Multiplex PCR analysis of clusters of unexplained viral respiratory tract infection in Cambodia
Conclusions: This is the first report of enterovirus 68 in Cambodia and contributes to the appreciation of this virus as an important respiratory pathogen. (Source: Virology Journal)
Source: Virology Journal - December 17, 2014 Category: Virology Authors: Nary LyRafal TokarzNischay MishraStephen SameroffKomal JainAgus RachmatUng AnSteven NewellDustin HarrisonW Lipkin Source Type: research

Real-time estimation of respiratory rate from a photoplethysmogram using an adaptive lattice notch filter
Background: Many researchers have attempted to acquire respiratory rate (RR) information from a photoplethysmogram (PPG) because respiration affects the waveform of the PPG. However, most of these methods were difficult to operate in real-time because of their complexity or computational requirements. From these needs, we attempted to develop a method to estimate RR from a PPG with a light computational burden. Methods: To obtain RR information, we adopt a sequential filtering structure and frequency estimation technique, which extracts a dominant frequency from a given signal. In particular, we used an adaptive lattice no...
Source: BioMedical Engineering OnLine - December 17, 2014 Category: Biomedical Engineering Authors: Chanki ParkBoreom Lee Source Type: research

Diagnosis and antimicrobial therapy of lung infiltrates in febrile neutropenic patients (allogeneic SCT excluded): updated guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO)
Up to 25% of patients with profound neutropenia lasting for >10 days develop lung infiltrates, which frequently do not respond to broad-spectrum antibacterial therapy. While a causative pathogen remains undetected in the majority of cases, Aspergillus spp., Pneumocystis jirovecii, multi-resistant Gram-negative pathogens, mycobacteria or respiratory viruses may be involved. In at-risk patients who have received trimethoprim–sulfamethoxazole (TMP/SMX) prophylaxis, filamentous fungal pathogens appear to be predominant, yet commonly not proven at the time of treatment initiation. Pathogens isolated from blood cultures...
Source: Annals of Oncology - December 17, 2014 Category: Cancer & Oncology Authors: Maschmeyer, G., Carratala, J., Buchheidt, D., Hamprecht, A., Heussel, C. P., Kahl, C., Lorenz, J., Neumann, S., Rieger, C., Ruhnke, M., Salwender, H., Schmidt-Hieber, M., Azoulay, E. Tags: reviews Source Type: research

The central role of mitochondria in axonal degeneration in multiple sclerosis
Neurodegeneration in multiple sclerosis (MS) is related to inflammation and demyelination. In acute MS lesions and experimental autoimmune encephalomyelitis focal immune attacks damage axons by injuring axonal mitochondria. In progressive MS, however, axonal damage occurs in chronically demyelinated regions, myelinated regions and also at the active edge of slowly expanding chronic lesions. How axonal energy failure occurs in progressive MS is incompletely understood. Recent studies show that oligodendrocytes supply lactate to myelinated axons as a metabolic substrate for mitochondria to generate ATP, a process which will ...
Source: Multiple Sclerosis - December 17, 2014 Category: Neurology Authors: Campbell, G. R., Worrall, J. T., Mahad, D. J. Tags: Topical Review Source Type: research

Two new nurse of the year award categories for 2015.
Authors: Abstract Nurses who specialise in diabetes or respiratory care will now be able to enter the Nursing Standard 2015 Nurse Awards after two new categories were announced. PMID: 25515442 [PubMed - in process] (Source: Nursing Standard)
Source: Nursing Standard - December 17, 2014 Category: Nursing Tags: Nurs Stand Source Type: research

Changes in Lung Volume and Ventilation Following Transition from Invasive to Non-invasive Respiratory Support and Prone Positioning in Preterm Infants.
Conclusion:Infants who are transitioned from invasive to non-invasive respiratory support are able to maintain their EELV and increase their VT. Prone positioning increases EELV and shifts tidal ventilation to the ventral lung regions. The latter suggests that infants should preferably be placed in prone position after extubation.Pediatric Research (2014); doi:10.1038/pr.2014.201. PMID: 25518010 [PubMed - as supplied by publisher] (Source: Pediatric Research)
Source: Pediatric Research - December 17, 2014 Category: Pediatrics Authors: van der Burg PS, Miedema M, de Jongh FH, Frerichs I, van Kaam AH Tags: Pediatr Res Source Type: research

Increased Resource Utilization in Lung Transplant Admissions in the Lung Allocation Score Era.
Conclusions: LAS implementation is associated with a significant increase in resource utilization during index hospitalization for lung transplant. PMID: 25517213 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - December 17, 2014 Category: Respiratory Medicine Authors: Maxwell BG, Mooney JJ, Lee PH, Levitt JE, Chhatwani L, Nicolls MR, Zamora MR, Valentine V, Weill D, Dhillon GS Tags: Am J Respir Crit Care Med Source Type: research

Novel Genes for Airway Wall Thickness Identified with Combined Genome Wide Association and Expression Analyses.
Conclusions Genetic variants contribute to AWT. Amongst others, the identified genes are involved in emphysema, airway obstruction and bronchial inflammation. PMID: 25517131 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - December 17, 2014 Category: Respiratory Medicine Authors: Dijkstra AE, Postma DS, van Ginneken B, Wielpütz MO, Schmidt M, Becker N, Owsijewitsch M, Kauczor HU, de Koning HJ, Lammers JW, Oudkerk M, Brandsma CA, Bossé Y, Nickle DC, Sin DD, Hiemstra PS, Wijmenga C, Smolonska J, Zanen P, Vonk JM, van den Berge M, Tags: Am J Respir Crit Care Med Source Type: research

The effects of oscillating positive expiratory pressure therapy in adults with stable non-cystic fibrosis bronchiectasis: A systematic review.
In conclusion, in stable non-CF bronchiectasis, oscillating PEP therapy is associated with improvement in sputum expectoration and QOL compared to no treatment. Compared to other ACTs, the effect upon sputum expectoration, lung function, gas exchange, and symptoms are equivalent. PMID: 25518845 [PubMed - as supplied by publisher] (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - December 17, 2014 Category: Respiratory Medicine Authors: Lee AL, Williamson HC, Lorensini S, Spencer LM Tags: Chron Respir Dis Source Type: research

Hepatotoxicity from antituberculous therapy in the elderly: A systematic review
Our analysis revealed that patients older than 60 had significantly more risk of hepatotoxicity. These studies suggest that a gentler regimen of treatment for older individuals could benefit health outcomes in this population of TB patients and minimize risks to the public's health. (Source: Tuberculosis)
Source: Tuberculosis - December 17, 2014 Category: Respiratory Medicine Authors: Jennifer D. Hosford, Michael E. von Fricken, Michael Lauzardo, Myron Chang, Yunfeng Dai, Jennifer A. Lyon, John Shuster, Kevin Fennelly Tags: Review Source Type: research

Comparison of CT-derived ventilation maps with deposition patterns of inhaled microspheres in rats
Experimental Lung Research, Ahead of Print. (Source: Experimental Lung Research)
Source: Experimental Lung Research - December 16, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Pulmonary preconditioning, injury, and inflammation modulate expression of the candidate tumor suppressor gene ECRG4 in lung
Experimental Lung Research, Ahead of Print. (Source: Experimental Lung Research)
Source: Experimental Lung Research - December 16, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Polymorphisms in key pulmonary inflammatory pathways and the development of acute respiratory distress syndrome
Experimental Lung Research, Ahead of Print. (Source: Experimental Lung Research)
Source: Experimental Lung Research - December 16, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Hypoxia-induced acute lung injury is aggravated in Streptozotocin diabetic mice
Experimental Lung Research, Ahead of Print. (Source: Experimental Lung Research)
Source: Experimental Lung Research - December 16, 2014 Category: Respiratory Medicine Tags: article Source Type: research

The pathogenesis of bleomycin-induced lung injury in animals and its applicability to human idiopathic pulmonary fibrosis
Experimental Lung Research, Ahead of Print. (Source: Experimental Lung Research)
Source: Experimental Lung Research - December 16, 2014 Category: Respiratory Medicine Tags: article Source Type: research

DNA methylation profile and expression of surfactant protein A2 gene in lung cancer
Experimental Lung Research, Ahead of Print. (Source: Experimental Lung Research)
Source: Experimental Lung Research - December 16, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Comprehensive analysis of genes, pathways, and TFs in nonsmoking Taiwan females with lung cancer
Experimental Lung Research, Ahead of Print. (Source: Experimental Lung Research)
Source: Experimental Lung Research - December 16, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Validation of a commercial serodiagnostic kit for diagnosing pulmonary Mycobacterium avium complex disease
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - December 16, 2014 Category: Respiratory Medicine Authors: Kitada, S.Yoshimura, K.Miki, K.Miki, M.Hashimoto, H.Matsui, H.Kuroyama, M.Ageshio, F.Kagawa, H.Mori, M.Maekura, R.Kobayashi, K. Tags: ORIGINAL ARTICLES Source Type: research

Tiotropium as part of inhaled polytherapy: Adherence and associated health‐care utilization
ConclusionsAdherence to Tiotropium was associated with decreased hospitalizations only among patients who improved their adherence to LABA and/or ICS as well. Exploring reasons for high non‐adherence and ways to improve adherence may optimize utilization of the scarce hospital resources. (Source: Respirology)
Source: Respirology - December 16, 2014 Category: Respiratory Medicine Authors: Tzahit Simon‐Tuval, Nimrod Maimon Tags: Original Article Source Type: research

The Dutch Functional Performance Inventory: Validity and Reliability in Patients With Chronic Obstructive Lung Disease
DiscussionScores on the Dutch FPI were reliable and reproducible. Evidence for validity was reasonable, but less strong than that reported in studies from other populations. (Source: Nursing Research)
Source: Nursing Research - December 16, 2014 Category: Nursing Tags: Feature Articles Source Type: research

Endobronchial ultrasound-guided transbronchial needle aspiration in lung cancer diagnosis and staging
Expert Review of Respiratory Medicine, Ahead of Print. (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - December 16, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Proceedings of the Bovine Respiratory Disease Symposium 2014: New Approaches to Bovine Respiratory Disease Prevention, Management, and Diagnosis
Editorial Amy E. Young, Amelia R. Woolums, Animal Health Research Reviews, Volume 15 Issue 02, pp 119-119Abstract (Source: Animal Health Research Reviews)
Source: Animal Health Research Reviews - December 16, 2014 Category: Veterinary Research Source Type: research

The impact of bovine respiratory disease: the current feedlot experience
Review Articles Michael Engler, Paul Defoor, Carter King, Justin Gleghorn, Animal Health Research Reviews, Volume 15 Issue 02, pp 126-129Abstract (Source: Animal Health Research Reviews)
Source: Animal Health Research Reviews - December 16, 2014 Category: Veterinary Research Source Type: research

Timely diagnosis of dairy calf respiratory disease using a standardized scoring system
Review Articles Sheila M. McGuirk, Simon F. Peek, Animal Health Research Reviews, Volume 15 Issue 02, pp 145-147Abstract (Source: Animal Health Research Reviews)
Source: Animal Health Research Reviews - December 16, 2014 Category: Veterinary Research Source Type: research