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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 5.

Gastric mucormycosis: Diagnosis by imprint cytology
We report a case of gastric mucormycosis in an immmunocompetent male patient, diagnosed by imprint cytology—a rare site and a rare setting. To the best of our knowledge, this is only the second report of gastric mucormycosis being diagnosed on cytology. As the disease is rapidly progressive and often fatal, early diagnosis is critical to the patient survival. Imprint cytology or brush cytology is extremely useful for the rapid diagnosis of gastric mucormycosis as these organisms are morphologically distinct. Familiarity with the cytomorphology of these organisms assists in the correct diagnosis of this disease. Diagn. Cy...
Source: Diagnostic Cytopathology - June 20, 2016 Category: Pathology Authors: Shilpa P. Tathe, Aarti A. Dani, Sanjay M. Chawhan, Saroj A. Meshram, Archana A. Randale, Waman K. Raut Tags: Brief Report Source Type: research

Changes of 2015 WHO Histological Classification of Lung Cancer 
and the Clinical Significance
Due in part to remarkable advances over the past decade in our understanding of lung cancer, particularly in area of medical oncology, molecular biology, and radiology, there is a pressing need for a revised classification, based not on pathology alone, but rather on an integrated multidisciplinary approach to classification of lung cancer. The 2015 World Health Organization (WHO) Classification of Tumors of the Lung, Pleura, Thymus and Heart has just been published with numerous important changes from the 2004 WHO classification. The revised classification has been greatly improved in helping advance the field, increasing...
Source: Chinese Journal of Lung Cancer - June 20, 2016 Category: Cancer & Oncology Source Type: research

Need for intensive care in patients admitted for asthma: Red flags from the social history
ConclusionAmong patients admitted to hospital for asthma, illicit substance abuse is a strong independent risk factor for intensive care requirement. Preventer therapy nonadherence further increases this risk. Lower socioeconomic status is also associated with increased risk. These historical features should be actively sought on admission and may serve as useful ‘red flags’ to prompt consideration of intensive monitoring. (Source: Respirology)
Source: Respirology - June 20, 2016 Category: Respiratory Medicine Authors: Fiona Moghaddas, Catherine Smith, David Pilcher, Robyn O'Hehir, Mark Hew, Eli Dabscheck Tags: Original Article Source Type: research

Phenotypic Destiny in Mitochondrial Disease?
Mitochondrial diseases are a group of heterogeneous disorders caused by inherited mutations in the mitochondrial genome (mtDNA) and nuclear genome. Typically, mutations in the mtDNA are maternally inherited and cause respiratory chain defects and account for a substantial fraction of childhood and adult neurometabolic disease, with an estimated prevalence of 1:5000 (0.02%). The most common mtDNA mutation is the mitochondrial 3243A>G mutation (m.3243A>G) in the MTTL1 gene (OMIM 590050), which encodes the transfer RNA tRNALeu(UUR). This mutation is associated with multiple clinical and psychiatric manifestations, including d...
Source: JAMA Neurology - June 20, 2016 Category: Neurology Source Type: research

Comparison of host genetic factors influencing pig response to infection with two North American isolates of porcine reproductive and respiratory syndrome virus
Porcine reproductive and respiratory syndrome (PRRS) is one of the most important swine diseases in the world and genetic selection of pigs for increased resistance to PRRS is an attractive method to improve t... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - June 20, 2016 Category: Genetics & Stem Cells Authors: Andrew S. Hess, Zeenath Islam, Melanie K. Hess, Raymond R. R. Rowland, Joan K. Lunney, Andrea Doeschl-Wilson, Graham S. Plastow and Jack C. M. Dekkers Source Type: research

Middle East respiratory syndrome coronavirus on inanimate surfaces: A risk for health care transmission
Publication date: Available online 20 June 2016 Source:American Journal of Infection Control Author(s): Raymond M. Khan, Hasan M. Al-Dorzi, Sameera Al Johani, Hanan H. Balkhy, Thamer H. Alenazi, Salim Baharoon, Yaseen M. Arabi The Middle East Respiratory syndrome coronavirus (MERS-CoV) has been responsible for multiple health care–associated outbreaks. We investigated whether high-touch surfaces in 3 rooms of laboratory-confirmed MERS-CoV patients were contaminated with MERS-CoV RNA. We found 2 out of 51 surfaces were contaminated with MERS-CoV viral genetic material. Hence, environmental contamination may be a ...
Source: American Journal of Infection Control - June 20, 2016 Category: Infectious Diseases Source Type: research

Sleep Disturbance in Caregivers of Children With Respiratory and Atopic Disease
Conclusions Deficient and poor-quality sleep in caregivers of children with chronic illness may have a significant impact on their health and well-being, as well as caregiving responsibilities. These data provide important information for pediatric psychologists working with these families. (Source: Journal of Pediatric Psychology)
Source: Journal of Pediatric Psychology - June 20, 2016 Category: Pediatrics Authors: Meltzer, L. J., Booster, G. D. Tags: Regular Articles Source Type: research

Pleural Lipoma Presenting With Back Pain
(Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 20, 2016 Category: Respiratory Medicine Authors: Tayfun Kermenli, Ahmet Cemal Pazarlı, Emre Akarsu, Timur Ekiz Tags: Letter to the Editor Source Type: research

Postoperative acute respiratory failure caused by adult‐onset Pompe disease
(Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 20, 2016 Category: Respiratory Medicine Authors: Dingyu Tan, Jun Xu, Yi Yang, Ming Gu, Xuezhong Yu Tags: Case Report Source Type: research

Evaluation of the rapid immunochromatographic ODK0501 assay for Streptococcus pneumoniae antigen detection with nasopharyngeal swabs: preliminary report
Conclusion RAPIRUN performed with nasopharyngeal swabs from adult patients exhibited lower sensitivity for the diagnosis of pneumococcal pneumonia than the other compared methods. The causative pathogen of pneumonia should be identified using not only sputum cultures or rapid antigen detection kits but also clinical features or gram staining of sputum. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - June 20, 2016 Category: Respiratory Medicine Source Type: research

Long-term follow-up after implantation of the Shelhigh(R) No-React(R) complete biological aortic valved conduit [ADULT CARDIAC]
CONCLUSIONS The Shelhigh® No-React® aortic valved conduit showed satisfactory short-term operative results. However, the long-term follow-up revealed a relatively high rate of deaths, which may be explained by the epidemiology of the patient group, but a substantial proportion of deaths could not be clarified. The overall rate of reoperation (8.6%) during the mid-term follow-up is worrisome and the failures due to aortoventricular disconnection, endocarditis and pseudoaneurysm formation remain unexplained. The redo-procedures were technically demanding. We recommend close follow-up of patients with the Shelhigh®...
Source: European Journal of Cardio-Thoracic Surgery - June 20, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Reineke, D. C., Kaya, A., Heinisch, P. P., Oezdemir, B., Winkler, B., Huber, C., Heijmen, R. H., Morshuis, W., Carrel, T. P., Englberger, L. Tags: Basic research vascular ADULT CARDIAC Source Type: research

Differences in Virulence Between Bovine-Derived Clinical Isolates of Pasteurella multocida Serotype A from the UK and the USA in a Model of Bovine Pneumonic Pasteurellosis
Publication date: Available online 20 June 2016 Source:Journal of Comparative Pathology Author(s): M.P. Dagleish, C.W. Bayne, G.G. Moon, J. Finlayson, J. Sales, J. Williams, J.C. Hodgson The time of onset and subsequent degree and progression of clinical signs, bacterial colonization and tissue pathology during experimental disease induced by intratracheal inoculation of either a UK or USA isolate of Pasteurella multocida serotype A recovered from clinical cases of bovine pneumonia were determined. Calves aged 8 weeks were challenged with 300 ml phosphate buffered saline (PBS) alone (group 1, n = 3, negative co...
Source: Journal of Comparative Pathology - June 20, 2016 Category: Pathology Source Type: research

Effects of positive end expiratory pressure administration during non‐invasive ventilation in patients affected by amyotrophic lateral sclerosis: A randomized crossover study
ConclusionIn ALS patients, PEEP application during NIV was associated with worse NIV and sleep quality and with higher sympathetic activity. (Source: Respirology)
Source: Respirology - June 20, 2016 Category: Respiratory Medicine Authors: Grazia Crescimanno, Francesca Greco, Salvo Arrisicato, Noemi Morana, Oreste Marrone Tags: Original Article Source Type: research

Factors associated with abnormal pulmonary function test among subjects with normal chest radiography: The Korean National Health and Nutrition Examination Survey
Determinants of abnormal lung function among subjects with normal chest radiography have not been widely evaluated. We investigated 12 109 participants with normal chest radiographs from the Korean National Health and Nutrition Examination Survey. Factors associated with abnormal pulmonary function were male gender, age ≥50, smoking history and a clinical history of cough or sputum production. Pulmonary function tests should be considered in population‐based screening, especially in men over 50 years old with a smoking history. (Source: Respirology)
Source: Respirology - June 20, 2016 Category: Respiratory Medicine Authors: Kum Ju Chae, Keun‐Sang Kwon, Gong Yong Jin, Heejung Bang, Juhyung Lee Tags: Scientific Letter Source Type: research

Short-Term Variation of Lung Function and Airway Inflammation in Children and Adolescents with Bronchiolitis Obliterans
Conclusions The short-term variability of sputum neutrophilia and lung function is low in BO patients. This finding should be considered to identify successful treatment in the individual patient and could be used as endpoints for future BO-related studies. (Source: Lung)
Source: Lung - June 20, 2016 Category: Respiratory Medicine Source Type: research

A 47‐year‐old woman with hypercapnia and altered mental status
Abstract Permissive hypercapnia is a commonly used ventilator strategy in attempt to improve refractory hypoxemia. The rationale of such practice is based on the assumption that hypercapnia, although associated with altered mental status, is well tolerated. Here, we report a case in which the altered mental status caused by hypercapnia is underlined by a life‐threatening mechanism. The case indicates the severity of hypercapnia may have been mistakenly overlooked in the past. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 20, 2016 Category: Respiratory Medicine Authors: Brian Bellucci, Renli Qiao Tags: CASE REPORT Source Type: research

Near‐peer teaching programme for medical students
We describe a student‐as‐teacher programme developed for fourth‐year students (MS4s) helping to deliver the second‐year Respiratory Pathophysiology course at our medical school. MethodsTwelve MS4s were paired with faculty members to co‐teach one or two small group case‐based sessions for second‐year students (MS2s). Beforehand, MS4s attended an orientation session and workshop, reviewing skills and strategies for teaching effectively. Following each teaching session co‐taught by MS4s, both MS4s and MS2s completed multiple‐choice surveys evaluating the MS4's teaching skills and the experience overall. MS4s...
Source: The Clinical Teacher - June 20, 2016 Category: Universities & Medical Training Authors: Zoe Gottlieb, Samantha Epstein, Jeremy Richards Tags: Original Article Source Type: research

Measuring the individual benefit of a medical or behavioral treatment using generalized linear mixed‐effects models
We propose statistical definitions of the individual benefit of a medical or behavioral treatment and of the severity of a chronic illness. These definitions are used to develop a graphical method that can be used by statisticians and clinicians in the data analysis of clinical trials from the perspective of personalized medicine. The method focuses on assessing and comparing individual effects of treatments rather than average effects and can be used with continuous and discrete responses, including dichotomous and count responses. The method is based on new developments in generalized linear mixed‐effects models, which...
Source: Statistics in Medicine - June 20, 2016 Category: Statistics Authors: Francisco J. Diaz Tags: Research Article Source Type: research

X-linked Hyper IgM Syndrome Presenting as Pulmonary Alveolar Proteinosis
Conclusions The clinical manifestations of XHIGM in our patient had several unique features, including the presentation with PAP, normal serum IgA, and expression of non-functional CD40L on activated T cells. To our knowledge, this is the first published case of PAP in a patient with XHIGM. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - June 20, 2016 Category: Allergy & Immunology Source Type: research

Efficacy, Safety, and Pharmacokinetics of a New 10 % Liquid Intravenous Immunoglobulin Containing High Titer Neutralizing Antibody to RSV and Other Respiratory Viruses in Subjects with Primary Immunodeficiency Disease
Conclusions There were zero serious bacterial infections, thus meeting the primary endpoint for this trial. The secondary endpoints including days missed from work due to infection, unscheduled visits to the physician, and days of hospitalization due to infection compared favorably to published reports of other IVIG products. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - June 20, 2016 Category: Allergy & Immunology Source Type: research

A hyperdense dot
Clinical introduction A 91-year-old man presented to the emergency department with drowsiness and right-sided weakness. He was last seen well 5 h ago. On examination, his GCS was E2V2M4; eyes were deviated to the left. Right upper motor neuron type facial nerve palsy, right-sided hypertonia and hyperreflexia were apparent. The initial non-contrast CT of the brain is shown (figure 1). Question Which artery is most likely occluded?Left middle cerebral artery Left internal carotid artery Basilar artery Left anterior cerebral artery Answer: B The initial scan showed left hyperdense internal carotid artery (ICA) sign (figu...
Source: Emergency Medicine Journal - June 20, 2016 Category: Emergency Medicine Authors: Ching, S., Ting, S. M. Tags: Pneumonia (infectious disease), TB and other respiratory infections, EMJ Image Challenge, Stroke, Radiology, Pneumonia (respiratory medicine), Clinical diagnostic tests, Ethics Source Type: research

Double staining of bacilli and antigen Ag85B improves the accuracy of the pathological diagnosis of pulmonary tuberculosis
Conclusions This new method, detecting both acid-fast bacilli and M. tuberculosis antigen, is a simple and sensitive method for the pathological diagnosis of tuberculosis and can be easily incorporated into routine tests of pathological laboratories. (Source: Journal of Clinical Pathology)
Source: Journal of Clinical Pathology - June 20, 2016 Category: Pathology Authors: Che, N., Qu, Y., Zhang, C., Zhang, L., Zhang, H. Tags: TB and other respiratory infections, Tuberculosis Original article Source Type: research

MERS and the dromedary camel trade between Africa and the Middle East
Abstract Dromedary camels are the most likely source for the coronavirus that sporadically causes Middle East respiratory syndrome (MERS) in humans. Serological results from archived camel sera provide evidence for circulation of MERS coronavirus (MERS-CoV) among dromedary camels in the Greater Horn of Africa as far back as 1983 and in Saudi Arabia as far back as 1992. High seroprevalences of MERS-CoV antibodies and the high virus prevalence in Saudi Arabian dromedary camels indicate an endemicity of the virus in the Arabian Peninsula, which predates the 2012 human MERS index case. Saudi Arabian dromedary camels s...
Source: Tropical Animal Health and Production - June 20, 2016 Category: Veterinary Research Source Type: research

Role of multiplex PCR analysis in children with febrile seizures
Conclusion Routine multiplex PCR analysis fosters the detection of respiratory viruses in children with febrile seizure. The precise role of multiplex analysis in the management of these children awaits further clarification. (Source: Wiener Medizinische Wochenschrift)
Source: Wiener Medizinische Wochenschrift - June 20, 2016 Category: Journals (General) Source Type: research

Cost effectiveness of amoxicillin for lower respiratory tract infections in primary care: an economic evaluation accounting for the cost of antimicrobial resistance.
CONCLUSION: Economic evaluation of antibiotic prescribing strategies that do not include the cost of resistance may provide misleading results that could be of questionable use to policymakers. However, further work is required to estimate robust costs of resistance. PMID: 27324629 [PubMed - as supplied by publisher] (Source: The British Journal of General Practice)
Source: The British Journal of General Practice - June 20, 2016 Category: Primary Care Authors: Oppong R, Smith RD, Little P, Verheij T, Butler CC, Goossens H, Coenen S, Moore M, Coast J Tags: Br J Gen Pract Source Type: research

Predictors of inadequate linezolid concentrations after standard dosing in critically ill patients.
In conclusion, presence of ARDS was identified as a new and strong predictor for insufficient linezolid concentrations, which might cause treatment failure. Insufficient concentrations might also be a major problem in patients with combined alterations of other covariate parameters. PMID: 27324768 [PubMed - as supplied by publisher] (Source: Antimicrobial Agents and Chemotherapy)
Source: Antimicrobial Agents and Chemotherapy - June 20, 2016 Category: Microbiology Authors: Taubert M, Zoller M, Maier B, Frechen S, Scharf C, Holdt LM, Frey L, Vogeser M, Fuhr U, Zander J Tags: Antimicrob Agents Chemother Source Type: research

Staphylococcus aureus alpha toxin is conserved amongst diverse hospital respiratory isolates collected from a global surveillance study and is neutralized by a monoclonal antibody MEDI4893.
This study demonstrates that Hla is conserved in diverse S. aureus isolates from around the world and is an attractive target for prophylactic mAb or vaccine development. PMID: 27324766 [PubMed - as supplied by publisher] (Source: Antimicrobial Agents and Chemotherapy)
Source: Antimicrobial Agents and Chemotherapy - June 20, 2016 Category: Microbiology Authors: Tabor DE, Yu L, Mok H, Tkaczyk C, Sellman BR, Wu Y, Oganesyan V, Slidel T, Jafri H, McCarthy M, Bradford P, Esser MT Tags: Antimicrob Agents Chemother Source Type: research

Takotsubo cardiomyopathy and its relevance to anesthesiology: a narrative review.
CONCLUSION: Perioperative TTCM is more common than appreciated and should be considered in any hospitalized patient presenting with acute coronary syndrome and/or hemodynamic instability, acute respiratory distress, as well as cardiac arrhythmias and arrest. PMID: 27324891 [PubMed - as supplied by publisher] (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - June 20, 2016 Category: Anesthesiology Authors: Hessel EA Tags: Can J Anaesth Source Type: research

Changes in breathomics from a 1‐year randomized smoking cessation trial of electronic cigarettes
ConclusionsSmokers invited to switch to electronic cigarettes who completely abstained from smoking showed steady progressive improvements in their exhaled breath measurements and symptoms scores. FeNo and eCO normalization is highly supportive of improved respiratory health outcomes and add to the notion that quitting from tobacco smoking can reverse harm in the lung.This article is protected by copyright. All rights reserved. (Source: European Journal of Clinical Investigation)
Source: European Journal of Clinical Investigation - June 20, 2016 Category: Journals (General) Authors: Davide Campagna, Fabio Cibella, Pasquale Caponnetto, Maria Domenica Amaradio, Massimo Caruso, Jaymin B. Morjaria, Mario Malerba, Riccardo Polosa Tags: Original Paper Source Type: research

Home or community-based pulmonary rehabilitation for individuals with chronic obstructive pulmonary disease: a systematic review and meta-analysis.
Abstract Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide, and outpatient pulmonary rehabilitation (OPR) has shown positive results. The aim of this study was to investigate the effects of home or community-based pulmonary rehabilitation (HCPR) in individuals with COPD. This systematic review and meta-analysis of randomized clinical trials compared HCPR to controls and HCPR to OPR according to functional capacity, dyspnea, and quality of life in individuals with COPD. 3,172 citations were identified in databases, and 23 were included in this review. HCPR proved su...
Source: Cadernos de Saude Publica - June 20, 2016 Category: Global & Universal Authors: Neves LF, Reis MH, Gonçalves TR Tags: Cad Saude Publica Source Type: research

Hospital-acquired respiratory viruses cause significant morbidity, mortality
BOSTON – Hospital-acquired respiratory viral infections may be a significant and underappreciated cause of morbidity and mortality among hospitalized patients. According to a multisite,... (Source: Internal Medicine News)
Source: Internal Medicine News - June 19, 2016 Category: Internal Medicine Source Type: research

Hospital-acquired respiratory viruses cause significant morbidity, mortality
BOSTON – Hospital-acquired respiratory viral infections may be a significant and underappreciated cause of morbidity and mortality among hospitalized patients. According to a multisite,... (Source: Hospitalist News)
Source: Hospitalist News - June 19, 2016 Category: Hospital Management Source Type: research

Diffuse alveolar damage ups death risk in acute respiratory distress syndrome
Among patients with acute respiratory distress syndrome (ARDS), those who are also diagnosed with diffuse alveolar damage (DAD) via an open lung biopsy face nearly twice as high a mortality risk as... (Source: Internal Medicine News)
Source: Internal Medicine News - June 19, 2016 Category: Internal Medicine Source Type: research

Diffuse alveolar damage ups death risk in acute respiratory distress syndrome
Among patients with acute respiratory distress syndrome (ARDS), those who are also diagnosed with diffuse alveolar damage (DAD) via an open lung biopsy face nearly twice as high a mortality risk as... (Source: Hospitalist News)
Source: Hospitalist News - June 19, 2016 Category: Hospital Management Source Type: research

Myasthenia gravis in patients with thymoma affects survival rate following extended thymectomy.
Authors: Zhang Z, Cui Y, Jia R, Xue L, Liang H Abstract Thymomas are the most common adult tumors in the anterior mediastinal compartment, and a significant amount of thymomas are complicated by myasthenia gravis (MG). Extended thymectomy (ET) is the primary treatment method for thymomas and is used to completely resect possible ectopic thymus to avoid recurrence. Studies on the effect of MG in thymoma patients following ET are limited. The aim of the present study was to determine whether the presence of MG affects the prognosis of patients with thymoma. The present study consisted of 104 patients with thymoma tha...
Source: Oncology Letters - June 19, 2016 Category: Cancer & Oncology Tags: Oncol Lett Source Type: research

Neonatal and Maternal Temperature Regulation During and After Delivery.
Abstract An important goal of obstetric anesthesia is to provide for the safety and comfort of the mother as well as to optimize physiologic outcomes for the neonate. Markers of neonatal physiologic outcome include cord umbilical artery pH and Apgar scores. Neonatal temperature has often been overlooked by anesthesiologists as an important physiologic outcome measure, but it may be significantly affected by operating room conditions and obstetric anesthesia technique at cesarean delivery. There is a dose-dependent increase in mortality with decreasing body temperature as well as an increased likelihood for more sev...
Source: Anesthesia and Analgesia - June 19, 2016 Category: Anesthesiology Authors: Perlman J, Kjaer K Tags: Anesth Analg Source Type: research

A Qualitative Investigation of the Impact of Asthma and Self-management Strategies among Older Adults.
CONCLUSIONS: Asthma had a distinct impact on elderly adults' quality of life; due to their longstanding history with this condition, many patients had accepted these symptoms as a "new normal." Developing strategies to reorient patients' perceptions of the possibilities for managing their illness will be critical to the success of asthma self-management support programs specific to older adults. PMID: 27315570 [PubMed - as supplied by publisher] (Source: Journal of Asthma)
Source: Journal of Asthma - June 19, 2016 Category: Respiratory Medicine Tags: J Asthma Source Type: research

Propofol-remifentanil anesthesia for upper airway endoscopy in spontaneous breathing patients: the ENDOTANIL randomized trial.
CONCLUSIONS: The adjunction of remifentanil to propofol TCI, at a dose that maintain spontaneous breathing, did not improve the conditions for pan endoscopy, but attenuates the hemodynamic response induced by upper airway stimulation. PMID: 27314599 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - June 19, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Using cysteine/cystine to overcome oxidative stress in goat oocytes and embryos cultured in vitro.
In conclusion, cysteine and cystine reduced the oxygen tension caused by H2O2, thereby providing a novel strategy for optimizing in vitro embryonic development systems. PMID: 27315595 [PubMed - as supplied by publisher] (Source: Molecular Medicine Reports)
Source: Molecular Medicine Reports - June 19, 2016 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Recombinant human brain natriuretic peptide attenuates LPS-induced cellular injury in human fetal lung fibroblasts via inhibiting MAPK and NF-κB pathway activation.
Authors: Song Z, Zhao X, Liu M, Jin H, Cui Y, Hou M, Gao Y Abstract Inflammatory responses are vital in lung injury diseases, particularly acute respiratory distress syndrome (ARDS). Recombinant human brain natriuretic peptide (rhBNP) has been shown to exhibit anti‑inflammatory effects in vivo in our previous studies. The present study aimed to investigate the mechanisms underlying the anti‑inflammatory effects of rhBNP on lipopolysaccharide (LPS)-induced human fetal lung fibroblasts (HFL-1). The results showed that LPS induced a significant increase in the leakage of lactate dehydrogenase and the secretion of...
Source: Molecular Medicine Reports - June 19, 2016 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Synergistic effect of ethno medicinal plants against biofilm forming Streptococcus pyogenes isolated from upper respiratory tract infection
The present study is an attempt to determine the synergistic anti-biofilm efficacy of three Indian medicinal plants namely Ocimum tenuiflorum, Plectranthus amboinicus, and Tylophora indica (OPT) against the biofilm forming Streptococcus pyogenes of upper respiratory tract infection. The leaves were collected and subjected to methanol extraction. The combined extract (OPT) was subjected to preliminary phytochemical and GC-MS analysis. About, ten isolates of S. pyogenes were obtained from the throat swabs samples and studied for biofilm forming potential. The strong biofilm forming isolates were subjected to Minimal Inhibito...
Source: International Journal of Phytomedicine - June 19, 2016 Category: Science Authors: MANIMEKALAI KANAGARAJAN Source Type: research

Aetiology of bronchiectasis in adults: A systematic literature review
Abstract While identifying the underlying aetiology is a key part of bronchiectasis management, the prevalence and impact of identifying the aetiologies on clinical management remain unclear. We aimed to determine the etiological spectrum of bronchiectasis, and how often etiological assessment could lead to the changes in patients' management. A comprehensive search was conducted using MEDLINE (via PubMed) and EMBASE for observational studies published before October 2015 reporting aetiologies in adults with bronchiectasis. Of the 8216 citations identified, 56 studies including 8608 adults with bronchiectasis were relevant...
Source: Respirology - June 19, 2016 Category: Respiratory Medicine Authors: Yong‐hua Gao, Wei‐jie Guan, Shao‐xia Liu, Lei Wang, Juan‐juan Cui, Rong‐chang Chen, Guo‐jun Zhang Tags: Systematic Review Source Type: research

Prevalence and management of recurrent respiratory papillomatosis (RRP) in the UK: cross‐sectional study
ConclusionsThe numbers of recurrent respiratory papillomatosis patients and Coblation procedures identified in England from a cross‐sectional survey and Hospital Episode Statistics were in broad agreement. Our study estimated 1.42 recurrent respiratory papillomatosis patients per 100 000 in the general UK population. We also estimated that Coblation procedures accounted for 3% of interventional treatments conducted in the UK recurrent respiratory papillomatosis population. (Source: Clinical Otolaryngology)
Source: Clinical Otolaryngology - June 19, 2016 Category: ENT & OMF Authors: A. J. Donne, K. Keltie, H. Cole, A.J. Sims, H. Patrick, S. Powell Tags: Original Article Source Type: research

The LINA Study: Higher Sensitivity of Infant Compared to Maternal Eosinophil/Basophil Progenitors to Indoor Chemical Exposures.
Conclusions. We demonstrate that infant's hematopoietic cells seem to respond with more sensitivity to environmental exposure compared to maternal cells. At least in infants, an activation of these hematopoietic cells by environmental exposure could contribute to an enhanced risk for the development of respiratory outcomes. PMID: 27313631 [PubMed - in process] (Source: Journal of Environmental and Public Health)
Source: Journal of Environmental and Public Health - June 18, 2016 Category: Environmental Health Tags: J Environ Public Health Source Type: research

Predicting Outcomes From Respiratory Distress: Does Another Score Help to Solve the Problem?*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Editorials Source Type: research

Ventilatory Strategies in Patients With Hematologic Malignancies and Acute Respiratory Failure: New Insights, New Questions, What Now?*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - June 18, 2016 Category: Emergency Medicine Tags: Editorials Source Type: research