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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 5.

Effect of the Pillar implant on snoring and mild obstructive sleep apnea: A multicenter study in Korea
ConclusionsIn selected Korean patients, the Pillar implant significantly improved not only subjective symptoms of mild SDB but also respiratory disturbances in mild OSA. Level of Evidence2b. Laryngoscope, 2014 (Source: The Laryngoscope)
Source: The Laryngoscope - October 24, 2014 Category: ENT & OMF Authors: Ji Ho Choi, Jae Hoon Cho, Yoo‐Sam Chung, Jeong‐Whun Kim, Sung Wan Kim Tags: Sleep Medicine Source Type: research

Middle East respiratory syndrome coronavirus (MERS-CoV) viral shedding in the respiratory tract: an observational analysis with infection control implications
Since the first description of Middle East respiratory syndrome coronavirus (MERS-CoV), it has not been known how long patients shed the virus in respiratory secretions. Thus, we analyzed the available data on time to negative MERS-CoV test in patients with confirmed MERS-CoV infection and asymptomatic positive contacts. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 24, 2014 Category: Infectious Diseases Authors: Ziad A. Memish, Abdullah M. Assiri, Jaffar A. Al-Tawfiq Source Type: research

Healthcare-associated respiratory tract infection and colonization in an intensive care unit caused by isolated in mouthwash
(Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 24, 2014 Category: Infectious Diseases Authors: Jeannete Zurita, Lorena Mejia, Sonia Zapata, Gabriel Trueba, Ana Cecilia Vargas, Samanta Aguirre, Guillermo Falconi Source Type: research

Subcutaneous implant with etonogestrel (Implanon(R)) for catamenial exacerbations in a patient with cystic fibrosis: a case report
Conclusion: Our case report supports the key role of female hormones in the development of PE and in the decline of lung function in a woman with CF. When appropriate, hormonal manipulation through contraceptive methods should be considered as potential treatment. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - October 24, 2014 Category: Respiratory Medicine Authors: Adelaida LamasLuis MáizMarta de ValbuenaJosé González-CasbasLucrecia Suárez Source Type: research

Opportunities for cystic fibrosis care teams to support treatment adherence
The purpose of this study was to identify the extent to which pediatric and adult cystic fibrosis (CF) care teams implement best practices in adherence assessment and counseling. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - October 24, 2014 Category: Respiratory Medicine Authors: Kristin A. Riekert, Michelle N. Eakin, Andrew Bilderback, Alana K. Ridge, Bruce C. Marshall Tags: Original Article Source Type: research

International guidelines for the management and treatment of Morquio A syndrome
Morquio A syndrome (mucopolysaccharidosis IVA) is a lysosomal storage disorder associated with skeletal and joint abnormalities and significant non‐skeletal manifestations including respiratory disease, spinal cord compression, cardiac disease, impaired vision, hearing loss, and dental problems. The clinical presentation, onset, severity and progression rate of clinical manifestations of Morquio A syndrome vary widely between patients. Because of the heterogeneous and progressive nature of the disease, the management of patients with Morquio A syndrome is challenging and requires a multidisciplinary approach, involving a...
Source: American Journal of Medical Genetics Part A - October 24, 2014 Category: Genetics & Stem Cells Authors: Christian J. Hendriksz, Kenneth I. Berger, Roberto Giugliani, Paul Harmatz, Christoph Kampmann, William G. Mackenzie, Julian Raiman, Martha Solano Villarreal, Ravi Savarirayan Tags: Research Review Source Type: research

Trends in licit and illicit drug-related deaths in Florida from 2001 to 2012
Drug misuse imposes significant burdens on societies worldwide, taking a considerable toll on the human lives from overdoses and diseases associated with drug use such as AIDS, hepatitis, and various hepatic, respiratory, and cardiovascular conditions [1]. High prevalence of suicides, accidents, and violent behaviors associated with drug use also contributes to the drug-related fatalities [1–3]. Globally, the drug-related mortality rate is estimated at 40 (range, 20.8-49.3) deaths per million among the population aged 15-64 years [4]. (Source: Forensic Science International)
Source: Forensic Science International - October 24, 2014 Category: Forensic Medicine Authors: Dayong Lee, Chris Delcher, Mildred M. Maldonado-Molina, Lindsay A.L. Bazydlo, Jon R. Thogmartin, Bruce A. Goldberger Source Type: research

A Non-BRICHOS SFTPC Mutant (SP-CI73T) Linked To Interstitial Lung Disease Promotes A Late Block In Macroautophagy Disrupting Cellular Proteostasis and Mitophagy.
Abstract Mutation of threonine for isoleucine at codon 73 (I73T) in the human surfactant protein C (hSP-C) gene (SFTPC) accounts for a significant portion of SFTPC mutations associated with interstitial lung disease (ILD). Cell lines stably expressing tagged proSP-C isoforms were generated to test the hypothesis that deposition of hSP-C(I73T) within the endosomal system promotes disruption of a key cellular quality control pathway, macroautophagy. By fluorescence microscopy, hSP-C(WT) co-localized with exogenously expressed hABCA3, an indicator of normal trafficking to lysosomal related organelles. In contrast, hSP...
Source: Am J Physiol Lung Ce... - October 24, 2014 Category: Respiratory Medicine Authors: Hawkins A, Guttentag SH, Deterding R, Funkhouser WK, Goralski JL, Chatterjee S, Mulugeta S, Beers MF Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Cigarette Smoke Enhances Proliferation and Extracellular Matrix Deposition By Human Fetal Airway Smooth Muscle.
In this study, we used canalicular stage (18-20 weeks gestational age) human fetal airway smooth muscle (fASM) cells as an in vitro model of the immature airway. fASM cells were exposed to cigarette smoke extract (CSE; 0.5-1.5% for 24-72 h) and cell proliferation, ECM deposition, and intracellular calcium ([Ca(2+)]i) responses to agonist (histamine 10 μM) were used to evaluate effects on remodeling and hyperreactivity. CSE significantly increased cell proliferation and deposition of ECM molecules collagen I, collagen III, and fibronectin. In contrast, [Ca(2+)]i responses were not significantly affected by CSE. Analysis of...
Source: Am J Physiol Lung Ce... - October 24, 2014 Category: Respiratory Medicine Authors: Vogel ER, VanOosten SK, Holman MA, Hohbein DD, Thompson MA, Vassallo R, Pandya HC, Prakash YS, Pabelick CM Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Subcutaneous implant with etonogestrel (Implanon®) for catamenial exacerbations in a patient with cystic fibrosis: a case report
Conclusion: Our case report supports the key role of female hormones in the development of PE and in the decline of lung function in a woman with CF. When appropriate, hormonal manipulation through contraceptive methods should be considered as potential treatment. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - October 24, 2014 Category: Respiratory Medicine Authors: Adelaida LamasLuis MáizMarta de ValbuenaJosé González-CasbasLucrecia Suárez Source Type: research

Efficacy and safety of enzyme replacement therapy with BMN 110 (elosulfase alfa) for Morquio A syndrome (mucopolysaccharidosis IVA): a phase 3 randomised placebo-controlled study
Conclusions Elosulfase alfa improved endurance as measured by the 6MWT in the weekly but not qow dose group, did not improve endurance on the 3MSCT, reduced urine KS, and had an acceptable safety profile. (Source: Journal of Inherited Metabolic Disease)
Source: Journal of Inherited Metabolic Disease - October 23, 2014 Category: Internal Medicine Source Type: research

Effectiveness of enzyme replacement therapy in adults with late-onset Pompe disease: results from the NCS-LSD cohort study
Conclusions These data provide some further evidence of the effectiveness of ERT in adults with late-onset Pompe disease. Synopsis The results of this longitudinal cohort study of 62 adults with late-onset Pompe disease, provide further evidence on the effectiveness of ERT in this rare condition. (Source: Journal of Inherited Metabolic Disease)
Source: Journal of Inherited Metabolic Disease - October 23, 2014 Category: Internal Medicine Source Type: research

Chronic respiratory conditions in a cohort of metropolitan fire-fighters: associations with occupational exposure and quality of life
Conclusions Ten percent of metropolitan fire-fighters reported underlying chronic respiratory conditions. Presence of such a condition in combination with suboptimal protection from inhaled exposures may lead to poorer physical HRQoL. (Source: International Archives of Occupational and Environmental Health)
Source: International Archives of Occupational and Environmental Health - October 23, 2014 Category: Occupational Health Source Type: research

Exercise training combined with psychological interventions for people with chronic obstructive pulmonary disease
The objective of this systematic review was to examine the effect of interventions which combine exercise training and psychological interventions for a range of health outcomes in people with COPD. Database searches identified randomized controlled trials of people with COPD participating in interventions that combined exercise training with a psychological strategy compared with control (usual care, waiting list) or active comparators (education, exercise, psychological interventions alone). Health outcomes included dyspnoea, anxiety, depression, quality of life or functional exercise capacity. Standardized mean differen...
Source: Respirology - October 23, 2014 Category: Respiratory Medicine Authors: Louise Wiles, Paul Cafarella, Marie T. Williams Tags: Review Source Type: research

CDC Kerala 13: Antenatal, Natal and Postnatal Factors Among Children (2–6 y) with Autism – A Case Control Study
Conclusions This case control study involving 143 children between 2 and 6 y with autism as per CARS criteria and a control group of 200 normal children has shown that excess fetal movement, maternal respiratory infection/asthma, maternal vaginal infection, maternal hypothyroidism and family history of neuro-developmental disorders are possible risk factors for autism. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - October 23, 2014 Category: Pediatrics Source Type: research

Outcome for self-expandable metal stents in patients with malignant gastroduodenal obstruction: A single center experience
Conclusion Metallic stent placement is an effective and relatively safe treatment for patients with malignant gastric outlet obstruction. (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - October 23, 2014 Category: Gastroenterology Source Type: research

Type 2 Diabetes Mellitus: The Concerned Complications and Target Organs
Publication date: September 2014 Source:Apollo Medicine, Volume 11, Issue 3 Author(s): Ashwini Kumar , Sudhanshu Kumar Bharti , Awanish Kumar Diabetes has been considered as the most dreaded non-communicable disease consuming the mankind rapidly. WHO has predicted the number of diabetics to be approximately 366 millions by 2030. The disease is characterized by hyperglycemia and the basic symptoms are polyphagia, polydipsia and polyuria. The autoimmune type 1 diabetes represent almost 1% of the total diabetic population, the rest being that of type 2 diabetes (T2D). Type 2 diabetes has been linked to a variety of factors ...
Source: Apollo Medicine - October 23, 2014 Category: Journals (General) Source Type: research

Guillain–Barré syndrome after acute myocardial infarction: A rare presentation
We report such a rare association of acute myocardial infarction and Guillain–Barré syndrome. Our patient underwent primary angioplasty successfully, but developed respiratory failure while in hospital. While the difficulty in weaning off from ventilator a suspicion of neuromuscular disease was made. The further investigations, including nerve conduction study confirmed a diagnosis of Guillain–Barré syndrome. Despite treatment, the patient died secondary to multi-organ dysfunction. Our case is 4th reported in the literature without use of any thrombolytic agent for such association. (Source: Apollo Medicine)
Source: Apollo Medicine - October 23, 2014 Category: Journals (General) Source Type: research

Exposure of mice to secondhand smoke elicits both transient and long‐lasting transcriptional changes in cancer‐related functional networks
ABSTRACT Secondhand smoke (SHS) has long been linked to lung cancer and other diseases in nonsmokers. Yet, the underlying mechanisms of SHS carcinogenicity in nonsmokers’ lung cancer remain to be elucidated. We investigated the immediate and long‐lasting effects of SHS exposure on gene expression in mice in vivo. We exposed mice whole body to SHS for 5 hours/day, 5 days/week for 4 months in exposure chambers of a microprocessor‐controlled smoking machine. Subsequently, we performed microarray gene expression profiling, genome‐wide, to construct the pulmonary transcriptome of SHS‐exposed mice, immediately after di...
Source: International Journal of Cancer - October 23, 2014 Category: Cancer & Oncology Authors: Stella Tommasi, Albert Zheng, Ahmad Besaratinia Tags: Carcinogenesis Source Type: research

Identifying Children’s Health Care Quality Measures for Medicaid and CHIP: An Evidence-Informed, Publicly Transparent Expert Process
Conclusions An open national public process combined with an evidence-informed evaluation methodology resulted in identification of a balanced, grounded, and parsimonious core set of measures that should become feasible to implement on a widespread scale over time. (Source: Academic Pediatrics)
Source: Academic Pediatrics - October 23, 2014 Category: Pediatrics Source Type: research

Implications of multiple freeze-thawing on respiratory samples for culture-independent analyses
Best practice when performing culture-independent microbiological analysis of sputum samples involves their rapid freezing and storage at −80°C. However, accessing biobanked collections can mean that material has been passed through repeated freeze–thaw cycles. The aim of this study was to determine the impact of these cycles on microbial community profiles. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - October 23, 2014 Category: Respiratory Medicine Authors: Leah Cuthbertson, Geraint B. Rogers, Alan W. Walker, Anna Oliver, Lucas R. Hoffman, Mary P. Carroll, Julian Parkhill, Kenneth D. Bruce, Christopher J. van der Gast Tags: Short Communication Source Type: research

Serial Intervals of Respiratory Infectious Diseases: A Systematic Review and Analysis
The serial interval of an infectious disease represents the duration between symptom onset of a primary case and symptom onset of its secondary cases. A good evidence base for such values is essential, because they allow investigators to identify epidemiologic links between cases and serve as an important parameter in epidemic transmission models used to design infection control strategies. We reviewed the literature for available data sets containing serial intervals and for reported values of serial intervals. We were able to collect data on outbreaks within households, which we reanalyzed to infer a mean serial interval...
Source: American Journal of Epidemiology - October 23, 2014 Category: Epidemiology Authors: Vink, M. A., Bootsma, M. C. J., Wallinga, J. Tags: RESEARCH-ARTICLE Source Type: research

Expression and targeting of lymphocyte function-associated antigen 1 (LFA-1) on white blood cells for treatment of allergic asthma.
We examined LFA-1 (CD11a) levels on PBMCs from patients with allergic asthma compared with healthy controls. Patients exhibited a significantly higher percentage of PBMCs expressing LFA-1 than healthy controls. Furthermore, the level of LFA-1 expression on patient PBMCs was greater than on healthy PBMCs. We identified a unique cellular population in patients that consisted of CD4(-) CD11a(hi) cells. We also evaluated LtxA in a HDM extract-induced mouse model for allergic asthma. LtxA caused resolution of disease in mice, as demonstrated by a decrease in BALF WBCs, a reduction in pulmonary inflammation and tissue remodeling...
Source: Journal of Leukocyte Biology - October 23, 2014 Category: Hematology Authors: Gupta A, Espinosa V, Galusha LE, Rahimian V, Miro KL, Rivera-Medina A, Kasinathan C, Capitle E, Aguila HA, Kachlany SC Tags: J Leukoc Biol Source Type: research

α-1 Antitrypsin Activates Protein Phosphatase 2A (PP2A) to Counter Lung Inflammatory Responses.
Abstract Rationale: α-1 antitrypsin (A1AT) was identified as a plasma protease inhibitor; however, it is now recognized as a multi-functional protein that modulates immunity, inflammation, proteostasis, apoptosis and cellular senescence. Like A1AT, protein phosphatase 2A (PP2A), a major serine-threonine phosphatase, regulates similar biological processes and plays a key role in COPD. Objectives: Given their common effects, this study investigated whether A1AT acts via PP2A to alter TNF signaling, inflammation and proteolytic responses in this disease. Methods: PP2A activity was measured in peripheral blood neutrop...
Source: American Journal of Respiratory and Critical Care Medicine - October 23, 2014 Category: Respiratory Medicine Authors: Geraghty P, Eden E, Pillai M, Campos M, McElvaney NG, Foronjy RF Tags: Am J Respir Crit Care Med Source Type: research

The Diagnosis of Neonatal Pulmonary Atelectasis Using Lung Ultrasound.
CONCLUSIONS: Lung ultrasound is an accurate and reliable method for diagnosing NPA, most importantly, it can find those occult lung atelectasis that could not be detected on CXR. Routine lung ultrasound is a useful method of diagnosing or excluding NPA in neonates. PMID: 25341049 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Liu J, Chen SW, Liu F, Li QP, Kong XY, Feng ZC Tags: Chest Source Type: research

Is Quadriceps Endurance Reduced in COPD?: A Systematic Review.
ConclusionQuadriceps endurance is reduced in individuals with COPD compared to healthy controls independent of the type of task performed. Background: Although the aerobic profile of the quadriceps muscle is reduced in COPD, there is conflicting evidence whether this leads to reduced quadriceps muscle endurance. We therefore performed a systematic review of studies comparing quadriceps endurance in individuals with COPD to healthy controls. Methods: Relevant studies were identified by searching six electronic databases (1946-2011). Full text articles were obtained after two researchers independently reviewed the ab...
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Evans RA, Kaplovitch E, Beauchamp MK, Dolmage TE, Goldstein RS, Gillies CL, Brooks D, Mathur S Tags: Chest Source Type: research

Identification and Genotyping of Mycobacterium Tuberculosis Isolated From Water and Soil Samples of a Metropolitan City.
ConclusionAlthough the dominant M. tuberculosis superfamilies in soil and water did not correspond to the dominant M. tuberculosis family in patients, the presence of circulating genotypes of MTB in soil and water highlight the risk of transmission. Background: The potential role of environmental M. tuberculosis in the epidemiology of tuberculosis (TB) remains unknown. We investigated the transmission of M. tuberculosis from humans to the environment and the possible transmission of M. tuberculosis from the environment to humans. Methods: A total of 1,500 samples were collected from three counties of the Tehran met...
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Velayati AA, Farnia P, Mozafari M, Malekshahian D, Farahbod AM, Seif S, Rahideh S, Mirsaeidi M Tags: Chest Source Type: research

Rates and Correlates of Relapse Following Emergency Department Discharge for Acute Asthma: A Canadian 20-Site Prospective Cohort Study.
Conclusions:Despite receiving guideline-concordant anti-inflammatory treatments at ED discharge, almost one-in-five patients relapsed within four weeks. Female sex, prolonged symptoms, treatment-related factors and markers of prior asthma severity were significantly associated with relapse. These results may help clinicians target more aggressive interventions for patients at high risk of relapse. Background: Acute asthma is a common emergency department (ED) presentation. In a prospective multicenter cohort study we determined the frequency and factors associated with asthma relapse following discharge from the ED. ...
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Rowe BH, Villa-Roel C, Majumdar SR, Abu-Laban RB, Aaron SD, Stiell IG, Johnson J, Senthilselvan A, for the AIR Investigators Tags: Chest Source Type: research

SURROGATE RECEPTIVITY TO PARTICIPATION IN CRITICAL ILLNESS GENETIC RESEARCH: Aligning Research Oversight and Stakeholder Concerns.
Conclusions:Expressing trust in health care providers and viewing genetic research favorably were associated with increased willingness for study enrollment while concern regarding breach of confidentiality and African American race had the opposite effect. Study setting had no bearing on willingness to participate. Background: Collection of genetic biospecimens as part of critical illness investigations is increasingly commonplace. Oversight bodies vary in restrictions imposed on genetic research, introducing inconsistencies in study design, potential for sampling bias, and the possibility of being overly prohibitive ...
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Freeman BD, Butler K, Bolcic-Jankovic D, Clarridge BR, Kennedy CR, LeBlanc J, Hull SC Tags: Chest Source Type: research

Self-management following an acute exacerbation of copd: a systematic review.
Conclusions: SM interventions delivered immediately post-AE vary widely and outcome measures are inconsistent, making it difficult to draw strong recommendations regarding its effectiveness. The evaluation of SM interventions, delivered by trained health care professionals to selected patients and which offer structured follow up, appears necessary. PMID: 25340578 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Harrison SL, Janaudis-Ferreira T, Brooks D, Desveaux L, Goldstein RS Tags: Chest Source Type: research

Impact of childhood anthropometry trends on adult lung function.
Conclusion:These data show evidence for a positive contribution of catch-up growth in early life to adult lung function. However, if weight gain or onset of obesity occurs after 5 years of age adverse impact on adult lung function is noted. Background: Poor fetal growth rate is associated with lower respiratory function; however there is limited understanding of the impact of growth trends and body mass index(BMI) during childhood on adult respiratory function. Methods: The present study data are from the Mater-University of Queensland Study of Pregnancy birth cohort. Prospective data were available from 1740 young...
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Suresh S, O'Callaghan M, Sly PD, Mamun AA Tags: Chest Source Type: research

Family-based psychosocial support and education as part of pulmonary rehabilitation in COPD: a randomized controlled trial.
Conclusions:This research supports family-based PR programs to enhance coping and psychosocial adjustment to illness of the family system. Clinical Trials registration number:NCT02048306. Background: Involving family as part of the patient's rehabilitation plan of care might enhance the management of Chronic Obstructive Pulmonary Disease (COPD). The primary aim of this study was to investigate the impact of a family-based pulmonary rehabilitation (PR) program on patients and family members' coping strategies to manage COPD. Methods: Family dyads (patient and family member) were randomly assigned to family-based (ex...
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Marques A, Jácome C, Cruz J, Gabriel R, Brooks D, Figueiredo D Tags: Chest Source Type: research

Impact of diagnostic criteria on the incidence of ventilator-associated pneumonia.
Conclusions:Applying different diagnostic criteria to the same patient population can result in wide variation in the incidence of VAP. The use of different criteria can also influence the time of diagnosis and the associated mortality rate. Background: Ventilator-associated pneumonia (VAP) is a frequent complication of prolonged invasive ventilation. Because VAP is largely preventable, its incidence has been used as an index of quality-of-care in the intensive care unit (ICU). However, the incidence of VAP varies according to which criteria are used to identify it. We compared the incidence of VAP obtained with differ...
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Ego A, Preiser JC, Vincent JL Tags: Chest Source Type: research

Sarcoidosis and cancer risk: systematic review and meta-analysis of observational studies.
Conclusions.The present meta-analysis suggests a significant, though moderate, association between sarcoidosis and malignancy. Background.: An increased cancer risk in sarcoidosis patients has been suggested, although results are conflicting in a number of case-control and cohort studies. We conducted a systematic review of all available data and performed a meta-analysis to better define and quantify the association between sarcoidosis and cancer. Methods.: We searched Medline and Embase for all original articles on cancer and sarcoidosis published up to January 2013. Two independent authors reviewed all titles/ab...
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Bonifazi M, Bravi F, Gasparini S, La Vecchia C, Gabrielli A, Wells AU, Renzoni EA Tags: Chest Source Type: research

Quality of Well-Being Outcomes in the National Emphysema Treatment Trial.
Conclusions:In comparison to maximal medical therapy alone, patients undergoing maximal medical therapy plus LVRS experienced improved health related quality of life and gained more quality-adjusted life years. ClinicalTrials.gov Identifier:NCT00000606. Background: Surgical and medical treatments for emphysema may affect both quality and quantity of life. The purpose of this paper is to report outcomes from the National Emphysema Treatment Trial (NETT) using an index that combines quality and quantity of life. Design: Prospective Randomized Clinical Trial. Following pulmonary rehabilitation, 1218 patients with seve...
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Kaplan RM, Sun Q, Ries AL Tags: Chest Source Type: research

Effect of Acute Arteriolar Vasodilation on Capacitance and Resistance in Pulmonary Arterial Hypertension.
Conclusions: In vasoresponsive PAH, PVC is a function of the pressure response of the vasoconstricted arterioles to stroke volume. Immediately upon vasodilation, the capacitance increases markedly. The compliance vessels are thus the same as the resistance vessels. The immediate reduction in Pa pressure during NO suggests that large vessel remodeling is not a major contributor to systolic pressure in these patients. PMID: 25340330 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Newman JH, Brittain EL, Robbins IM, Hemnes AR Tags: Chest Source Type: research

Isoniazid-associated hepatitis in HIV-infected adults receiving thirty-six months isoniazid prophylaxis in Botswana.
Conclusions: HIV-infected adults receiving 36IPT did not have an increased incidence of moderate-to-severe hepatitis or hepatic encephalopathy compared with published reports among HIV-infected or -uninfected persons in trials or public health programs. Compared with participants not receiving ART, the risk of moderate-to-severe hepatitis was not increased by ART. PMID: 25340318 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Tedla Z, Nguyen ML, Sibanda T, Nyirenda S, Agizew TB, Girde S, Rose CE, Samandari T Tags: Chest Source Type: research

Monitoring the enzyme expression in a respiratory chain of Corynebacterium glutamicum in a copper ion-supplemented culture medium.
Abstract Corynebacterium glutamicum has a branched respiratory chain: one of the branches is cytochrome bcc complex and cytochrome aa3-type cytochrome c oxidase, and the other is cytochrome bd-type menaquinol oxidase. The factors that influence the expression patterns of these respiratory enzymes remain unclear. To investigate the expressional control mechanism of the enzymes, we have previously constructed a promoter assay system utilizing enhanced green fluorescence protein. Here, we monitored respiratory enzymes' expression by using this system during growth in various culture media, with and without Cu(2+) ion ...
Source: Bioscience, Biotechnology, and Biochemistry - October 23, 2014 Category: Biochemistry Authors: Kusumoto T, Aoyagi M, Sugiyama T, Sakamoto J Tags: Biosci Biotechnol Biochem Source Type: research

Zoogloea oleivorans sp. nov., a new floc-forming, petroleum hydrocarbon degrading bacterium isolated from biofilm.
Abstract A floc-forming, Gram-negative, petroleum hydrocarbon degrading bacterial strain designated as BucT was isolated from a petroleum hydrocarbon contaminated site in Hungary. Phylogenetic analysis based on 16S rRNA gene sequence revealed that strain BucT formed a distinct phyletic lineage within the genus Zoogloea. Its closest relative is Zoogloea caeni EMB43T (97.2%) followed by Zoogloea oryzae A-7T (95.9%), Zoogloea ramigera ATCC 19544T (95.5%) and Zoogloea resiniphila DhA-35T (95.4%). Level of DNA-DNA relatedness between strain BucT and Z. caeni EMB43T is 31.6%. Cells of strain BucT are facultatively aerobi...
Source: International Journal of Systematic and Evolutionary Microbiology - October 23, 2014 Category: Microbiology Authors: Farkas M, Táncsics A, Kriszt B, Benedek T, Toth EM, Keki Z, Veres PG, Szoboszlay S Tags: Int J Syst Evol Microbiol Source Type: research

Chitinophaga qingshengii sp. nov., isolated from weathered rock surface.
Abstract A novel type of mineral-weathering bacterium was isolated from weathered rock (potassic trachyte) surfaces collected from Nanjing (Jiangsu, China). Cells of strain JN246T were Gram-stain-negative, rod-shaped, and non-motile. Strain JN246T was aerobic, catalase- and oxidase-positive, and grew optimally at 28 °C and pH 7.0. On the basis of 16S rRNA gene sequence analysis, strain JN246T belonged to the genus Chitinophaga and the closest phylogenetic relatives were Chitinophaga eiseniae YC6729T (98.5 %), Chitinophaga terrae KP01T (96.8 %), and Chitinophaga jiangningensis JN53T (96.3 %). The major respiratory ...
Source: International Journal of Systematic and Evolutionary Microbiology - October 23, 2014 Category: Microbiology Authors: Cheng C, Wang Q, He LY, Huang Z, Sheng XF Tags: Int J Syst Evol Microbiol Source Type: research

Airway Metabolome and Chronic Lung Disease of Prematurity
Bronchopulmonary dysplasia (BPD) is the most common pulmonary sequela of prematurity, affecting about 30% of all very low birth weight premature infants.1,2 Although pulmonary morbidity decreases in the majority of children with BPD with somatic and, presumably, lung growth in the first 2 years of life, there is a subset of children who persist with respiratory symptoms into their childhood and adolescent years.3 Persistence of pulmonary disease in childhood, referred to as chronic lung disease of prematurity, is often associated with failure to thrive, school absences attributable to frequent exacerbations, and poor qual...
Source: The Journal of Pediatrics - October 23, 2014 Category: Pediatrics Authors: Deepa Rastogi, Judy L. Aschner Tags: Editorial Source Type: research

All-time high tularaemia incidence in Norway in 2011: report from the national surveillance
This article describes the epidemiological and clinical features of tularaemia cases during a year with exceptionally high tularaemia incidence. Data from the national reference laboratory for tularaemia combined with epidemiological data from the Norwegian Surveillance System for Communicable Diseases (MSIS) were used. The incidence of tularaemia varied greatly between counties, but almost every county was involved. The majority (77.8 %) of the cases were diagnosed during the autumn and winter months. The geographic distribution also showed seasonal patterns. Overall, oropharyngeal tularaemia (41.1 %) was the most commo...
Source: European Journal of Clinical Microbiology and Infectious Diseases - October 22, 2014 Category: Microbiology Source Type: research

"Chest"[ta]; +984 new citations
984 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Chest"[ta] These pubmed results were generated on 2014/10/22PubMed, a service of the National Library of Medicine, includes over 15 million citations for biomedical articles back to the 1950's. These citations are from MEDLINE and additional life science journals. PubMed includes links to many sites providing full text articles and other related resources. (Source: Chest)
Source: Chest - October 22, 2014 Category: Respiratory Medicine Tags: Report Source Type: research

Antimicrobial usage among hospitalized children in Latvia: A neonatal and pediatric antimicrobial point prevalence survey.
CONCLUSIONS: We identified a few problematic areas, which need improvement: the high use of third-generation cephalosporins for pediatric patients, prolonged surgical prophylaxis, predominant use of parenteral antibiotics and an urgent need for local antibiotic guidelines. PMID: 25323546 [PubMed - in process] (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - October 22, 2014 Category: Universities & Medical Training Authors: Sviestina I, Mozgis D Tags: Medicina (Kaunas) Source Type: research

Home mechanical ventilation in South Korea.
CONCLUSION: Noninvasive management was preferred over invasive ones, and transition to the former was a result of PM&R interventions. PMID: 25323913 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - October 22, 2014 Category: Universities & Medical Training Authors: Kim DH, Kang SW, Choi WA Tags: Yonsei Med J Source Type: research

A promising concept of combination therapy for positional obstructive sleep apnea
Conclusions The results of this study indicate that combination of SPT + MAD leads to a higher therapeutic efficacy in patients with sdOSA under MAD therapy when compared to one of the treatment modalities alone. (Source: Sleep and Breathing)
Source: Sleep and Breathing - October 22, 2014 Category: Respiratory Medicine Source Type: research