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Respiratory Medicine

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 5.

Lung flute improves symptoms and health status in COPD with chronic bronchitis: A 26 week randomized controlled trial
Conclusions: The Lung Flute is a safe and effective treatment in COPD with chronic bronchitis, providing a wide array of benefits.ClinicalTrials.gov IdentifierNCT01186822 (Source: Clinical and Translational Medicine)
Source: Clinical and Translational Medicine - September 23, 2014 Category: Internal Medicine Authors: Sanjay SethiJingjing YinPamela Anderson Source Type: research

Pathogenesis of Gallibacterium anatis in a natural infection model fulfils Koch's postulates: 2. Epididymitis and decreased semen quality are the predominant effects in specific pathogen free roosters.
In conclusion, the present study provides novel data on the impact of a G. anatis infection in roosters in a natural infection model elucidating on bacterial distribution, pathological lesions as well as influences on semen quality. PMID: 25246024 [PubMed - as supplied by publisher] (Source: Avian Pathology)
Source: Avian Pathology - September 23, 2014 Category: Pathology Authors: Paudea S, Liebhart D, Aurich C, Hess M, Hess C Tags: Avian Pathol Source Type: research

Prognostic Value of Plateau Pressure Below 30 cm H2O in Septic Patients With Acute Respiratory Failure.
CONCLUSIONS: Pplat within the first 24 h of ICU admission is predictive of outcome, with lower Pplat associated with lower mortality rates. There is no safety margin for Pplat. Limiting Pplat should be considered even at < 30 cm H2O in septic patients with acute respiratory failure. PMID: 25249650 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - September 23, 2014 Category: Respiratory Medicine Authors: Chan MC, Tseng JS, Chiu JT, Hsu KH, Shih SJ, Yi CY, Wu CL, Kou YR Tags: Respir Care Source Type: research

Relation of Exercise Capacity With Lung Volumes Before and After 6-Minute Walk in Subjects With COPD.
CONCLUSIONS: In subjects with stable COPD, lung volumes measured immediately after 6MWT are more closely related to exercise limitation than baseline lung volumes measured before 6MWT, except for FEV1. Therefore, pulmonary function testing immediately after exercise should be included in future studies on COPD for the assessment of exercise-induced ventilatory constraints to physical performance that cannot be adequately assessed from baseline pulmonary function testing at rest. PMID: 25249649 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - September 23, 2014 Category: Respiratory Medicine Authors: Wibmer T, Rüdiger S, Kropf-Sanchen C, Stoiber KM, Rottbauer W, Schumann C Tags: Respir Care Source Type: research

Azithromycin Attenuates Pulmonary Inflammation and Emphysema in Smoking-Induced COPD Model in Rats.
CONCLUSIONS: Azm attenuates pulmonary emphysema by partly reversing the decrease in the numbers of inflammatory cells (neutrophil and macrophage) and VEGF secretion and VEGFR2 protein expression in smoking-induced COPD in rats. PMID: 25249648 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - September 23, 2014 Category: Respiratory Medicine Authors: Wan YF, Huang ZH, Jing K, Li J, Wang Y, Xu CQ, Chen JH, Zhen YL Tags: Respir Care Source Type: research

Cough Characteristics and FVC Maneuver in Cystic Fibrosis.
CONCLUSIONS: The cough flow/volume maneuver reveals abnormalities in cough velocities and volume. A low secondary spike correlates with FEV1 severity level. The method may lead to earlier intervention to assist cough in CF. PMID: 25249647 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - September 23, 2014 Category: Respiratory Medicine Authors: Vilozni D, Lavie M, Ofek M, Sarouk I, Efrati O Tags: Respir Care Source Type: research

Salinithrix halophila gen. nov, sp. nov., a halophilic bacterium in the family Thermoactinomycetaceae.
Abstract A halophilic actinomycete, strain R4S8T was isolated from soil of Inche-Broun hypersaline wetland in the north of Iran. The isolate grew aerobically at temperatures of 30-50 °C (optimum temperature 40 °C), pH 6-10 (optimum pH 7.0) and NaCl concentrations 1-15 % w/v (optimum 3-5 %). It formed short and straight to moderately flexuous aerial mycelium without motile elements. The cell wall of strain R4S8T contained meso-diaminopimelic acid as diaminoacid without any diagnostic sugars. The polar lipid pattern consisted of phosphatidylglycerol, diphosphatidylglycerol, phosphatidylethanolamine, phosphatidyl se...
Source: International Journal of Systematic and Evolutionary Microbiology - September 23, 2014 Category: Microbiology Authors: Zarparvar P, Amoozegar MA, Moshtaghi Nikou M, Schumann P, Ventosa A Tags: Int J Syst Evol Microbiol Source Type: research

Altererythrobacter oceanensis sp. nov., isolated from the Western Pacific.
Abstract A Gram-stain negative, ovoid-rod shaped, strictly aerobic bacterium, strain Y2(T), was isolated from a deep-sea sediment of the Western Pacific. Phylogenetic and phenotypic properties of the organism indicated that it belongs to the genus Altererythrobacter. Strain Y2(T) shares highest 16S rRNA gene sequence similarity of 96.6 % with Erythrobacter jejuensis CNU001(T), followed by the type strains of recognized members of the genus Altererythrobacter (94.8-96.5 %). Strain Y2(T) forms a clade with E. jejuensis CNU001(T) in the cluster of species of the genus Altererythrobacter. Growth of strain Y2(T) was o...
Source: Antonie van Leeuwenhoek - September 23, 2014 Category: Microbiology Authors: Yang Y, Zhang G, Sun Z, Cheung MK, Huang C Tags: Antonie Van Leeuwenhoek Source Type: research

Venovenous extracorporeal membrane oxygenation in patients with atrial septal defects.
Abstract Two patients presented in profound respiratory distress unresponsive to maximal support and were placed on venovenous ECMO. Subsequently, both were found to have a patent foramen ovale and high pulmonary artery pressures, resulting in a right to left shunt. Both patients had a better than expected response to ECMO, likely related to their shunts allowing oxygenated blood to bypass the high pulmonary artery pressures and go directly to the left heart. Both patients were successfully weaned from ECMO and discharged to home in good condition. PMID: 25249517 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Julliard W, Niles S, Maloney J Tags: Perfusion Source Type: research

Structure-function relationships and mechanical properties of pulmonary surfactant membranes.
Abstract The respiratory surface in the mammalian lung is stabilized by pulmonary surfactant, a membrane-based system composed of multiple lipids and specific proteins, the primary function of which is to minimize the surface tension at the alveolar air-liquid interface, optimizing the mechanics of breathing and avoiding alveolar collapse, especially at the end of expiration. The goal of the present review is to summarize current knowledge regarding the structure, lipid-protein interactions and mechanical features of surfactant membranes and films and how these properties correlate with surfactant biological functi...
Source: Chemistry and Physics of Lipids - September 23, 2014 Category: Lipidology Authors: Parra E, Pérez-Gil J Tags: Chem Phys Lipids Source Type: research

Altered Serum Cytokine Signature in Common Variable Immunodeficiency
Conclusions Presented data suggest that the altered cytokine profile observed in patients with CVID may be attributed to the activation of monocyte-macrophage and granulocyte lineages, possibly driven by the translocation of bacterial components across the gastrointestinal or respiratory tracts mucosal barrier. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - September 23, 2014 Category: Allergy & Immunology Source Type: research

[Series] Surveillance for emerging respiratory viruses
Several new viral respiratory tract infectious diseases with epidemic potential that threaten global health security have emerged in the past 15 years. In 2003, WHO issued a worldwide alert for an unknown emerging illness, later named severe acute respiratory syndrome (SARS). The disease caused by a novel coronavirus (SARS-CoV) rapidly spread worldwide, causing more than 8000 cases and 800 deaths in more than 30 countries with a substantial economic impact. Since then, we have witnessed the emergence of several other viral respiratory pathogens including influenza viruses (avian influenza H5N1, H7N9, and H10N8; variant inf...
Source: The Lancet Infectious Diseases - September 22, 2014 Category: Infectious Diseases Authors: Jaffar A Al-Tawfiq, Alimuddin Zumla, Philippe Gautret, Gregory C Gray, David S Hui, Abdullah A Al-Rabeeah, Ziad A Memish Tags: Series Source Type: research

[Articles] Safety and immunogenicity of a candidate tuberculosis vaccine MVA85A delivered by aerosol in BCG-vaccinated healthy adults: a phase 1, double-blind, randomised controlled trial
Further clinical trials assessing the aerosol route of vaccine delivery are merited for tuberculosis and other respiratory pathogens. (Source: The Lancet Infectious Diseases)
Source: The Lancet Infectious Diseases - September 22, 2014 Category: Infectious Diseases Authors: Iman Satti, Joel Meyer, Stephanie A Harris, Zita-Rose Manjaly Thomas, Kristin Griffiths, Richard D Antrobus, Rosalind Rowland, Raquel Lopez Ramon, Mary Smith, Sharon Sheehan, Henry Bettinson, Helen McShane Tags: Articles Source Type: research

[Comment] Emerging respiratory tract infections
Emerging and re-emerging respiratory tract infectious diseases and the growing problem of antimicrobial resistance continue to challenge diagnostic, treatment, prevention, and control strategies. Respiratory tract infections with epidemic and pandemic potential have plagued people since the dawn of human history. Comprehensive assessments of the global burden of disease show that respiratory tract infections are some of the commonest causes of morbidity and mortality worldwide, imposing a huge burden on health services. (Source: The Lancet Infectious Diseases)
Source: The Lancet Infectious Diseases - September 22, 2014 Category: Infectious Diseases Authors: Alimuddin Zumla, David S Hui, Jaffar A Al-Tawfiq, Phillipe Gautret, Brian McCloskey, Ziad A Memish Tags: Comment Source Type: research

[Comment] Case definition and management of patients with MERS coronavirus in Saudi Arabia
Exponential increases in the number of cases of the Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia in March, 2014, led to the appointment of Adel Fakeih as acting Minister of Health on April 21, 2014. He made the control of the MERS outbreak a top priority in the country's health agenda. An advisory council was set up to urgently develop scientific evidence-based plans to control the MERS outbreak and prevent human-to-human and animal-to-human transmission; an appropriate management algorithm, including best-practice guidelines for accurate diagnosis, infection control, intensive care, emergency me...
Source: The Lancet Infectious Diseases - September 22, 2014 Category: Infectious Diseases Authors: Tariq A Madani Tags: Comment Source Type: research

AstraZenaca's Pearl Therapeutics expands Durham laboratory – again
California drug company Pearl Therapeutics will again nearly double its laboratory flex space in the Imperial Center business park in Durham for a second year in a row. The respiratory drug firm has signed a lease to expand into the remaining 13,000 square feet of lab space in the Royal Center I building on Emperor Boulevard, according to the building’s owner, Boston-based Longfellow Real Estate Partners. Pearl, which was acquired by AstraZeneca (NYSE: AZM) in July 2013 for $1.15 billion, will… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - September 22, 2014 Category: Pharmaceuticals Authors: Amanda Jones Hoyle Source Type: research

AstraZenaca's Pearl Therapeutics expands Durham laboratory – again
California drug company Pearl Therapeutics will again nearly double its laboratory flex space in the Imperial Center business park in Durham for a second year in a row. The respiratory drug firm has signed a lease to expand into the remaining 13,000 square feet of lab space in the Royal Center I building on Emperor Boulevard, according to the building’s owner, Boston-based Longfellow Real Estate Partners. Pearl, which was acquired by AstraZeneca (NYSE: AZM) in July 2013 for $1.15 billion, will… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 22, 2014 Category: Biotechnology Authors: Amanda Jones Hoyle Source Type: research

Prevalence and risk factors associated with nonspecific building‐related symptoms in office employees in Japan: relationships among work environment, indoor air quality, and occupational stress
This article is protected by copyright. All rights reserved. (Source: Indoor Air)
Source: Indoor Air - September 22, 2014 Category: Occupational Health Authors: Kenichi Azuma, Koichi Ikeda, Naoki Kagi, U Yanagi, Haruki Osawa Tags: Original Article Source Type: research

Duration of day care attendance during infancy predicts asthma at the age of seven: the Cincinnati Childhood Allergy and Air Pollution Study
ConclusionDepending on duration of attendance, day care during infancy can either increase or reduce risk of asthma at the age of seven. (Source: Clinical and Experimental Allergy)
Source: Clinical and Experimental Allergy - September 22, 2014 Category: Allergy & Immunology Authors: G. Cheng, A. M. Smith, L. Levin, T. Epstein, P. H. Ryan, G. K. LeMasters, G. K. Khurana Hershey, T. Reponen, M. Villareal, J. Lockey, D. I. Bernstein Tags: Original Article Source Type: research

Comparisons of subunit 5A and 5B isozymes of yeast cytochrome c oxidase
Subunit 5 of Saccharomyces cerevisiae CcO is essential for assembly and has two isoforms, 5A and 5B. 5A is expressed under normoxic conditions while 5B is expressed at very low oxygen tensions. As a consequence, COX5A-deleted strains (Δcox5A) have no or only low levels of CcO under normoxic conditions rendering them respiratory-deficient. Previous studies reported that respiratory growth could be restored by combining Δcox5A with mutations of ROX1 that encodes a repressor of COX5B expression. In these mutants 5B isozyme expression level was 30-50 % of wild type (5A isozyme) and exhibited a maximum catalytic a...
Source: BJ Energy - September 22, 2014 Category: Biochemistry Authors: R Dodia, B Meunier, C W.M. Kay, P R Rich Tags: BJ Energy Source Type: research

Non-rhinovirus enteroviruses associated with respiratory infections in Peru (2005-2010)
Conclusion: This study provides data about the serotypes of EVs circulating in Peru and sets the need for further studies. (Source: Virology Journal)
Source: Virology Journal - September 22, 2014 Category: Virology Authors: Jose HuamanGladys CarrionJulia AmpueroJorge GomezVictor OcañaIrmia PazElizabeth GomezEdward ChavezFavio SarmientoEdward PozoV Laguna-TorresEric Halsey Source Type: research

Validating Hospital Admission Criteria for Decision Support in Pneumonia
Conclusions: Our admission criteria agreed acceptably with overall observed admission decisions for patients presenting to EDs with pneumonia, but may safely reduce hospital admission rates and increase recognition of patients at risk for outpatient failure compared to CURB-65 >= 2 or A-DROP >= 2. (Source: BMC Pulmonary Medicine - Latest articles)
Source: BMC Pulmonary Medicine - Latest articles - September 22, 2014 Category: Respiratory Medicine Authors: Barbara JonesJason JonesCaroline VinesNathan Dean Source Type: research

Perinatal features of the RASopathies: Noonan syndrome, Cardiofaciocutaneous syndrome and Costello syndrome
We report on the perinatal presentation of 10 patients with Noonan syndrome (NS), nine with Cardiofaciocutaneous syndrome (CFCS) and three with Costello syndrome (CS), in conjunction with the results of a comprehensive literature review. The majority of perinatal findings in NS, CS, and CFCS are shared: polyhydramnios; prematurity; lymphatic dysplasia; macrosomia; relative macrocephaly; respiratory distress; hypotonia, as well as cardiac and renal anomalies. In contrast, fetal arrhythmia and neonatal hypoglycemia are relatively specific to CS. NS, CS, and CFCS should all be considered as a possible diagnosis in pregnancies...
Source: American Journal of Medical Genetics Part A - September 22, 2014 Category: Genetics & Stem Cells Authors: Angela Myers, Jonathan A. Bernstein, Marie‐Luise Brennan, Cynthia Curry, Edward D. Esplin, Jamie Fisher, Margaret Homeyer, Melanie A. Manning, Eric A. Muller, Anna‐Kaisa Niemi, Laurie H. Seaver, Susan R. Hintz, Louanne Hudgins Tags: Research Article Source Type: research

Hyaluronic Acid as Capacitation Inductor: Metabolic Changes and Membrane‐Associated Adenylate Cyclase Regulation
Contents The aim of this research was to study the effect of hyaluronic acid on bovine cryopreserved spermatozoa compared with heparin as regards the variation of capacitation induction, cellular oxidative metabolism and intracellular signal induced by membrane‐associated adenylate cyclase to propose hyaluronic acid as a capacitation inductor. Heparin or hyaluronic acid and lysophosphatidylcholine were used to induce sperm capacitation and acrosome reaction, respectively. 2′,5′‐dideoxyadenosine was used as a membrane‐associated adenylate cyclase inhibitor. The highest percentages of capacitated spermatozoa and li...
Source: Reproduction in Domestic Animals - September 22, 2014 Category: Reproduction Medicine Authors: S Fernández, M Córdoba Tags: Original Article Source Type: research

Prior Decompensation is associated with Delayed Mortality in Patients with Acute‐on‐chronic Liver Failure
ConclusionsACLF patients with or without PD had comparable short‐term prognosis but differential 1‐year mortality. ACLF patients with PD were distinct from those without PD in age, types of acute insults, severity of hepatic damage and distribution of complications and the former group was characterized by increased delayed mortality. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - September 22, 2014 Category: Gastroenterology Authors: Yu Shi, Minghua Zheng, Yang Ying, Wei Wu, Qiao Yang, Yihua Wu, Huadong Yan Tags: Clinical Hepatology Source Type: research

Age-Associated Changes in Immune Function: Impact of Vitamin E Intervention and the Underlying Mechanisms.
Abstract Numerous studies have provided evidence suggesting that aging is associated with significant adverse changes in the immune system, a phenomenon often called immunosenescence, which may be responsible for an observed increase in morbidity and mortality from infectious disease and cancer in the elderly. While a variety of immune cells are known to be affected by aging, declined T cell function is the most striking and best characterized feature of immunosenescence. Both intrinsic changes in T cells and alteration in extrinsic factors are involved. Nutritional intervention has been promoted as a promising app...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 22, 2014 Category: Endocrinology Authors: Wu D, Meydani SN Tags: Endocr Metab Immune Disord Drug Targets Source Type: research

Symptomatic treatment of the cough in whooping cough.
CONCLUSIONS: There is insufficient evidence to draw conclusions about the effectiveness of interventions for the cough in whooping cough. More high-quality trials are needed to assess the effectiveness of potential antitussive treatments in patients with whooping cough. PMID: 25243777 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - September 22, 2014 Category: Journals (General) Authors: Wang K, Bettiol S, Thompson MJ, Roberts NW, Perera R, Heneghan CJ, Harnden A Tags: Cochrane Database Syst Rev Source Type: research

Clinical pathways for chronic cough in children.
CONCLUSIONS: Current evidence suggests that using a clinical algorithm for the management of children with chronic cough in hospital outpatient settings is more effective than providing wait-list care. Futher high-quality randomised controlled trials are needed to perform ongoing evaluation of cough management pathways in general practitioner and other primary care settings. PMID: 25242448 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - September 22, 2014 Category: Journals (General) Authors: McCallum GB, Bailey EJ, Morris PS, Chang AB Tags: Cochrane Database Syst Rev Source Type: research

Proteome analysis in the assessment of ageing.
Abstract Based on demographic trends, the societies in many developed countries are facing an increasing number and proportion of people over the age of 65. The raise in elderly populations along with improved health-care will be concomitant with an increased prevalence of ageing-associated chronic conditions like cardiovascular, renal, and respiratory diseases, arthritis, dementia, and diabetes mellitus. This is expected to pose unprecedented challenges both for individuals and societies and their health care systems. An ultimate goal of ageing research is therefore the understanding of physiological ageing and th...
Source: Ageing Research Reviews - September 22, 2014 Category: Genetics & Stem Cells Authors: Nkuipou-Kenfack E, Koeck T, Mischak H, Pich A, Schanstra JP, Zürbig P, Schumacher B Tags: Ageing Res Rev Source Type: research

Chromium-induced nephrotoxicity and ameliorative effect of carvedilol in rats: Involvement of oxidative stress, apoptosis and inflammation.
In conclusion, the findings of the present study demonstrated that carvedilol is an effective chemoprotectant against potassium dichromate-induced nephrotoxicity in rats. PMID: 25245570 [PubMed - as supplied by publisher] (Source: Chemico-Biological Interactions)
Source: Chemico-Biological Interactions - September 22, 2014 Category: Molecular Biology Authors: Sahu BD, Koneru M, Bijargi SR, Kota A, Sistla R Tags: Chem Biol Interact Source Type: research

Medical foot pump compressors have been available for many years as an option for human powered nebulisation.
PMID: 25230769 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - September 21, 2014 Category: Respiratory Medicine Authors: Masters N Tags: NPJ Prim Care Respir Med Source Type: research

Depression and heart failure associated with clinical COPD questionnaire outcome in primary care COPD patients: a cross-sectional study.
CONCLUSIONS: CCQ outcomes are higher in COPD patients with heart failure and depression. These findings might imply that heart failure and depression affect HRQoL of patients with COPD, and thus emphasise the importance of a holistic approach of this complex disease, leading to a correct diagnosis of COPD and its comorbidities, to achieve better tailored treatment of chronic patients. PMID: 25230736 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - September 21, 2014 Category: Respiratory Medicine Authors: Urff M, van den Berg JW, Uil SM, Chavannes NH, Damoiseaux RA Tags: NPJ Prim Care Respir Med Source Type: research

Effects of hyperbaric oxygen therapy as hepatic preconditioning in rats submitted to hepatic ischemia/reperfusion injury.
CONCLUSION: Hyperbaric preconditioning improved hepatic mitochondrial function and decreased serum markers of liver injury in the ischemia and reperfusion process. PMID: 25229517 [PubMed - in process] (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - September 21, 2014 Category: Surgery Authors: Losada DM, Chies AB, Feres O, Chaib E, D'Albuquerque LA, Castro-E-Silva O Tags: Acta Cir Bras Source Type: research

A comparison of surfactant administration through i-gel and ET-tube in the treatment of respiratory distress syndrome in newborns weighing more than 2000 grams.
CONCLUSION: According to the results of this study, the surfactant administration using i-gel was more successful in oxygenation improvement than the INSURE method, and the i-gel method could even be promoted to the standard care position. However, more research is needed in this area. PMID: 25221763 [PubMed] (Source: Biomed Res)
Source: Biomed Res - September 21, 2014 Category: Research Authors: Sadeghnia A, Tanhaei M, Mohammadizadeh M, Nemati M Tags: Adv Biomed Res Source Type: research

Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease
Conclusions: We found genome-wide significant associations with CB COPD on 4q22.1 (FAM13A) and 11p15.5 (EFCAB4A, CHID1 and AP2A2), and a locus associated with CB within COPD subjects on 1q23.3 (RPL31P11 and ATF6). This study provides further evidence that genetic variants may contribute to phenotypic heterogeneity of COPD.Trial registrationClinicalTrials.gov NCT00608764, NCT00292552 (Source: Respiratory Research)
Source: Respiratory Research - September 21, 2014 Category: Respiratory Medicine Authors: Jin LeeMichael ChoCraig HershMerry-Lynn McDonaldJames CrapoPer BakkeAmund GulsvikAlejandro ComellasChristine WendtDavid LomasVictor KimEdwin Silverman Source Type: research

Occurrences of Yawn and Swallow are Temporally Related
Abstract Yawning is a stereotyped motor behavior characterized by deep inhalation and associated dilation of the respiratory tract, pronounced jaw opening, and facial grimacing. The frequency of spontaneous yawning varies over the diurnal cycle, peaking after waking and before sleep. Yawning can also be elicited by seeing or hearing another yawn, or by thinking about yawning, a phenomenon known as “contagious yawning”. Yawning is mediated by a distributed network of brainstem and supratentorial brain regions, the components of which are shared with other airway behaviors including respiration, swallowing, and ...
Source: Dysphagia - September 21, 2014 Category: Speech Therapy Source Type: research

Halodurantibacterium flavum gen. nov., sp. nov., a Non-phototrophic Bacterium Isolated from an Oil Production Mixture.
Abstract Three Gram-negative bacterial strains, DQW12E6-69-1(T), DQW12E61-22-1, and DQW12E6-22-1-1, were isolated from an oil production mixture from Daqing Oilfield, northeastern China. The phylogenetic analysis based on the 16S rRNA gene sequences revealed that the three strains formed a stable cluster different from the known genus in Rhodobacteraceae of Alphaproteobacteria. In addition, they were most closely related to species in genera Pararhodobacter, Rhodobacter ,and Rhodobaca with the 16S rRNA gene sequence similarities being 95.1-95.9 %. Cells of the three strains were aerobic; they do not require salt t...
Source: Current Microbiology - September 21, 2014 Category: Microbiology Authors: Lv XL, Xie BS, Cai M, Tang YQ, Wang YN, Cui HL, Liu XY, Tan Y, Wu XL Tags: Curr Microbiol Source Type: research

A case of Clostridium difficile infection complicated by acute respiratory distress syndrome treated with fecal microbiota transplantation.
Abstract Acute respiratory distress syndrome is a life-threatening disorder caused mainly by pneumonia. Clostridium difficile infection (CDI) is a common nosocomial diarrheal disease. Disruption of normal intestinal flora by antibiotics is the main risk factor for CDI. The use of broad-spectrum antibiotics for serious medical conditions can make it difficult to treat CDI complicated by acute respiratory distress syndrome. Fecal microbiota transplantation is a highly effective treatment in patients with refractory CDI. Here we report on a patient with refractory CDI and acute respiratory distress syndrome caused by ...
Source: World Journal of Gastroenterology : WJG - September 21, 2014 Category: Gastroenterology Authors: Kim JE, Gweon TG, Yeo CD, Cho YS, Kim GJ, Kim JY, Kim JW, Kim H, Lee HW, Lim T, Ham H, Oh HJ, Lee Y, Byeon J, Park SS Tags: World J Gastroenterol Source Type: research

Trends in hospital admissions at a Department for Infectious Diseases in Italy from 1995 to 2011 and implications for health policies
Conclusions: Older age, a higher number of comorbidities, a longer hospital LOS for certain conditions, and a higher rate of HSOT characterize the patients admitted to this ID department in recent years. Despite progress in treatment and management, infectious diseases continue to be a major threat to human health. The current challenge for ID departments is the treatment of complex cases, often associated with chronic diseases in elderly patients. Continuous monitoring at a local and national level will allow early identification of changes in the epidemiological patterns of IDs and provide information for healthcare syst...
Source: BioMed Central - September 20, 2014 Category: Journals (General) Authors: Giovanna OrlandoGuido GubertiniCristina NegriMassimo CoenElena RicciMassimo GalliGiuliano Rizzardini Source Type: research

Is C-reactive protein testing useful to predict outcome in patients with acute bronchitis?
Conclusion. Among patients with uncomplicated acute bronchitis and discoloured sputum, the CRP concentrations at presentation are not helpful for predicting symptom resolution. (Source: Family Practice)
Source: Family Practice - September 20, 2014 Category: Primary Care Authors: Llor, C., Plana-Ripoll, O., Moragas, A., Bayona, C., Morros, R., Pera, H., Miravitlles, M. Tags: Epidemiology Source Type: research

Social Isolation in Individuals with Chronic Respiratory Failure Undergoing Long‐Term Oxygen Therapy
(Source: Journal of the American Geriatrics Society)
Source: Journal of the American Geriatrics Society - September 20, 2014 Category: Geriatrics Authors: Hiroo Wada, Yoko Akiyama, Hirotaka Takeda, Masuo Nakamura, Hajime Takizawa Tags: Letters to the Editor Source Type: research

Can short-term heart rate variability be used to monitor fentanyl–midazolam induced changes in ANS preceding respiratory depression?
Abstract Opioids have an occasional but high-risk side effect of respiratory depression. The detection of critical respiratory depression usually occurs after the event. Earlier detection would be beneficial in preventing increased morbidity and mortality of 0.01 % patients receiving analgesic opioids. Airway patency during inspiration requires vagal modulation. Regulation of the cardiovascular and respiratory centres may be coupled with a central mechanism that is indirectly measurable with heart rate variability (HRV). While opioids tend to increase parasympathetic tone, a decrease in airway stability could be ...
Source: Journal of Clinical Monitoring and Computing - September 20, 2014 Category: Information Technology Source Type: research

How to manage ventilation in pediatric acute respiratory distress syndrome?
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - September 20, 2014 Category: Intensive Care Source Type: research