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Respiratory Medicine

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 5.

Endotoxin depletion of recombinant protein preparations through their preferential binding to histidine tags.
Abstract The presence of endotoxins in preparations of recombinantly produced therapeutic proteins poses serious problems for patients. Endotoxins can cause fever, respiratory distress syndromes, intravascular coagulation or endotoxic shock. A number of methods have been devised to remove endotoxins from protein preparations, using separation procedures based on molecular mass or charge properties. Most of the methods are limited in their endotoxin removal capacities and lack general applicability. We are describing a biotechnological approach for endotoxin removal. This strategy exploits the observation that endot...
Source: Analytical Biochemistry - August 26, 2014 Category: Biochemistry Authors: Mack L, Brill B, Delis N, Groner B Tags: Anal Biochem Source Type: research

Nanotubes in the human respiratory tract - Deposition Modeling.
Abstract Deposition of inhaled single-wall carbon nanotubes (SWCNT) and multi-wall carbon nanotubes (MWCNT) in the respiratory tract was theoretically investigated for various age groups (infants, children, adolescents, and adults). Additionally, possible effects of the inhalative flow rate on nanotube deposition were simulated for adult lungs. Theoretical computations were based on the aerodynamic diameter concept and the assumption of particles being randomly transported through a stochastic (close-to-realistic) lung structure. Deposition of nanotubes was calculated by application of well validated empirical depo...
Source: Medical Physics - August 26, 2014 Category: Physics Authors: Sturm R Tags: Z Med Phys Source Type: research

Reducing hospital admissions and improving the diagnosis of COPD in Southampton City: methods and results of a 12-month service improvement project.
CONCLUSIONS: The use of medical intelligence to investigate the underlying processes of COPD hospital admissions led to an effective intervention delivered in a consultant-led model. PMID: 25141877 [PubMed - in process] (Source: Respiratory Care)
Source: Respiratory Care - August 25, 2014 Category: Respiratory Medicine Authors: Wilkinson T, North M, Bourne SC Tags: NPJ Prim Care Respir Med Source Type: research

Roche To Acquire Intermune
Acquisition: Swiss drugmaker expands in respiratory disease area with purchase of one-drug firm (Source: Chemical and Engineering News)
Source: Chemical and Engineering News - August 25, 2014 Category: Chemistry Authors: Ann M. Thayer Source Type: research

Respiratory Services of WNY expands into Rochester market
A growing respiratory services firm in Western New York is expanding outside the region through acquisition. Subscribe to one of our free daily newsletters. From our daily Morning and Afternoon Editions to weekly customized newsletters that include national headlines for a range of industries. Respiratory Services of Western New York Inc., a Cheektowaga-based provider, has completed the purchase of Durable Medical Equipment and Supplies Ltd., including locations in LeRoy and Honeoye Falls. Terms… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - August 25, 2014 Category: American Health Authors: Tracey Drury Source Type: research

Mini-symposium: Childhood obesity and its impact on respiratory wellbeing: Editorial title: Childhood obesity is the global warming of healthcare
The discussion of obesity and its detrimental impact upon recent generations has sparked much interest but comparatively little success in implementing preventative strategies . The rates of child overweight and obesity continue to climb internationally in a problem that is no longer isolated to the developed world . Indeed, in a country like Australia that prides itself on its sporty outdoor lifestyles, we presently have 26% of our children as overweight or obese and 63% of our adult population similarly disposed. Moreover, the issue is of greater urgency in our indigenous population, with the proportion of overweight and...
Source: Paediatric Respiratory Reviews - August 25, 2014 Category: Respiratory Medicine Authors: Dominic A. Fitzgerald Tags: Mini-Symposium: Obesity and the Respiratory system Source Type: research

Index
Note: Page numbers of article titles are in boldface type. Abuse (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 25, 2014 Category: Respiratory Medicine Source Type: research

Forthcoming Issues
Acute Respiratory Distress Syndrome (ARDS) Lorraine B. Ware, Julie A. Bastarache, and Carolyn Calfee, Editors (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 25, 2014 Category: Respiratory Medicine Source Type: research

Contributors
CAROLYN M. D’AMBROSIO, MD, MS Director, The Center for Sleep Medicine, Tufts Medical Center; Associate Professor of Medicine, Pulmonary, Critical Care, and Sleep Medicine Division, Tufts University School of Medicine, Boston, Massachusetts (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 25, 2014 Category: Respiratory Medicine Source Type: research

Contents
Carolyn M. D'Ambrosio Kelly Newton, Vipin Malik, and Teofilo Lee-Chiong (Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 25, 2014 Category: Respiratory Medicine Source Type: research

CME Accreditation Page
(Source: Clinics in Chest Medicine)
Source: Clinics in Chest Medicine - August 25, 2014 Category: Respiratory Medicine Source Type: research

Successful transportation managing common respiratory conditions of precious cargo: becoming an expert neonatal transport nurse.
PMID: 25136748 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Authors: Snow TM Tags: Adv Neonatal Care Source Type: research

Managing common neonatal respiratory conditions during transport.
This article reviews the history of respiratory management during neonatal transport and discusses current methodologies and innovations in transport respiratory management. PMID: 25136752 [PubMed - in process] (Source: Advances in Neonatal Care)
Source: Advances in Neonatal Care - August 25, 2014 Category: Nursing Authors: Coe KL, Jamie SF, Baskerville RM Tags: Adv Neonatal Care Source Type: research

The frequency of tetracycline resistance genes co-detected with respiratory pathogens: a database mining study uncovering descriptive trends throughout the United States
Conclusions: Significant trends were uncovered regarding the co-detection frequencies of TRGs and respiratory pathogens over time. It is valuable for the field of public health to monitor trends regarding the spread of resistant infectious disease, especially since tetracycline continues to be utilized a treatment for various microbial infections. Analyzing large datasets containing TEM-PCR results for co-detections provides valuable insights into trends of antibiotic resistance gene expression so that the effectiveness of first-line treatments can be continuously monitored. (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - August 25, 2014 Category: Infectious Diseases Authors: Matthew HuffDavid WeismanJohn AdamsSong LiJessica GreenLeslie MaloneScott Clemmons Source Type: research

Respiratory tract clinical sample selection for microbiota analysis in patients with pulmonary tuberculosis
Conclusions: Respiratory tract microbial communities were similar in terms of the major phyla identified, yet they varied in terms of relative abundances and diversity indexes. Oropharynx communities varied with respect to health status and resembled those in sputum samples, which are collected from tuberculosis patients only due to the difficulty in obtaining sputum from healthy individuals, suggesting that oropharynx samples can be used to analyze community structure alterations associated with tuberculosis. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - August 25, 2014 Category: Epidemiology Authors: Luz Elena BoteroLuisa Delgado-SerranoMartha Lucía CepedaJose Ricardo BustosJuan Manuel AnzolaPatricia Del PortilloJaime RobledoMaría Mercedes Zambrano Source Type: research

Repair Rate and Durability of Video Assisted Minimally Invasive Mitral Valve Surgery
ConclusionsMIMVS is a safe approach with low morbidity and mortality that allows a high and durable repair rate with low reoperation rates and favorable short‐term event‐free survival. (Source: Journal of Cardiac Surgery)
Source: Journal of Cardiac Surgery - August 25, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Diana Reser, Mathias van Hemelrijck, Jovana Pavicevic, Anna Platzmann, Etem Caliskan, Volkmar Falk, Stephan Jacobs Tags: Original Article Source Type: research

Clinicopathological Features and Outcomes of Gastric Cancer Patients with Pulmonary Lymphangitis Carcinomatosa
Conclusions Pulmonary lymphangitis carcinomatosa caused by gastric cancer has some specific clinicopathological features. While the prognosis of gastric cancer patients with pulmonary lymphangitis carcinomatosa is extremely poor, some patients may have survival benefit from chemotherapy. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - August 25, 2014 Category: Cancer & Oncology Authors: Funakoshi, T., Yasui, H., Boku, N., Fukutomi, A., Yamazaki, K., Machida, N., Todaka, A., Tsushima, T., Yokota, T., Onozawa, Y., Kenmotsu, H., Endo, M. Tags: Gastrointestinal Medicine, Original Articles Source Type: research

Role of aerodigestive clinics in evaluation, care of children with chronic respiratory complaints [FOCUS ON SUBSPECIALTIES]
(Source: AAP News)
Source: AAP News - August 25, 2014 Category: Pediatrics Authors: Moore, P. E., Wootten, C. T. Tags: Focus on Subspecialties, Pulmonology Source Type: research

Does Early Second-Trimester Sonography Predict Adverse Perinatal Outcomes in Monochorionic Diamniotic Twin Pregnancies?
Conclusions— In our cohort, only second-trimester abdominal circumference and estimated fetal weight discordances in monochorionic diamniotic twin pregnancies were predictive of adverse composite obstetric outcomes. Twin-twin transfusion syndrome and adverse neonatal outcomes were not predicted by any of the intertwin discordances measured. (Source: Journal of Ultrasound in Medicine)
Source: Journal of Ultrasound in Medicine - August 25, 2014 Category: Radiology Authors: Allaf, M. B., Campbell, W. A., Vintzileos, A. M., Haeri, S., Javadian, P., Shamshirsaz, A. A., Ogburn, P., Figueroa, R., Wax, J., Markenson, G., Chavez, M. R., Ravangard, S. F., Ruano, R., Sangi-Haghpeykar, H., Salmanian, B., Meyer, M., Johnson, J., Ozhan Tags: Original Research Source Type: research

Utility of respiratory ward‐based NIV in acidotic hypercapnic respiratory failure
ConclusionsNIV could be used on medical wards for patients with pH 7.16 or greater on their first admission, although more conservative values should continue to be used for those with a second or subsequent episodes of AHRF. (Source: Respirology)
Source: Respirology - August 25, 2014 Category: Respiratory Medicine Authors: Chirag Dave, Alice Turner, Ajit Thomas, Ben Beauchamp, Biman Chakraborty, Asad Ali, Rahul Mukherjee, Dev Banerjee Tags: Original Article Source Type: research

Influenza pathogenesis: Club cells take the "cure"
Insight from Thomas Braciale (left) and Taeg Kim The illness that follows influenza A virus (IAV) infection results from both direct effects of IAV replication in the respiratory tract (RT) and from sequelae... (Source: The Journal of Experimental Medicine)
Source: The Journal of Experimental Medicine - August 25, 2014 Category: Internal Medicine Authors: Braciale, T., Kim, T. Tags: Insights Source Type: research

Long-term survival of influenza virus infected club cells drives immunopathology
In this report, we identify cells that become infected, but survive, acute influenza virus infection. We demonstrate that these cells, known as club cells, elicit a robust transcriptional response to virus infection, show increased interferon stimulation, and induce high levels of proinflammatory cytokines after successful viral clearance. Specific depletion of these surviving cells leads to a reduction in lung tissue damage associated with IAV infection. We propose a model in which infected, surviving club cells establish a proinflammatory environment aimed at controlling virus levels, but at the same time contribute to l...
Source: The Journal of Experimental Medicine - August 25, 2014 Category: Internal Medicine Authors: Heaton, N. S., Langlois, R. A., Sachs, D., Lim, J. K., Palese, P., tenOever, B. R. Tags: Brief Definitive Reports Source Type: research

Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing
Although specific antibody induced by pathogens or vaccines is a key component of protection against infectious threats, some viruses, such as dengue, induce antibody that enhances the development of infection. In contrast, antibody-dependent enhancement of bacterial infection is largely unrecognized. Here, we demonstrate that in a significant portion of patients with bronchiectasis and Pseudomonas aeruginosa lung infection, antibody can protect the bacterium from complement-mediated killing. Strains that resist antibody-induced, complement-mediated killing produce lipopolysaccharide containing O-antigen. The inhibition of...
Source: The Journal of Experimental Medicine - August 25, 2014 Category: Internal Medicine Authors: Wells, T. J., Whitters, D., Sevastsyanovich, Y. R., Heath, J. N., Pravin, J., Goodall, M., Browning, D. F., O'Shea, M. K., Cranston, A., De Soyza, A., Cunningham, A. F., MacLennan, C. A., Henderson, I. R., Stockley, R. A. Tags: Articles Source Type: research

A chalcone with potent inhibiting activity against biofilm formation of nontypeable Haemophilus influenzae
In this study, a series of natural and synthetic chalcones with various chemical substituents were evaluated in vitro for their antibiofilm activities against strong biofilm‐forming strains of NTHi. Of the test chalcones, 3‐hydroxychalcone (chalcone 8) exhibited the most potent inhibitory activity, with mean minimum biofilm inhibitory concentration (MBIC50) value of 16 μg/mL (71.35 μM), or approximately 6‐fold more active than azithromycin (MBIC50 419.68 μM), the reference drug. The inhibitory activity of chalcone 8 which was a chemically modified chalcone, appeared to be superior to those of natural chalcones tes...
Source: Microbiology and Immunology - August 25, 2014 Category: Microbiology Authors: Duangkamol Kunthalert, Sudarat Baothong, Pichit Khetkam, Suwadee Chokchaisiri, Apichart Suksamrarn Tags: Original Article Source Type: research

Assessment of respiratory mechanics with forced oscillations in healthy newborns
ConclusionsNoninvasive measurement of Zrs can be made in neonates during natural sleep with a high success rate, even in the first hours of life. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - August 25, 2014 Category: Respiratory Medicine Authors: Zoltán Hantos, Dorottya Czövek, Zita Gyurkovits, Hajnalka Szabó, Balázs A. Maár, Bence Radics, Katalin Virág, Gergely Makan, Hajnalka Orvos, Zoltán Gingl, Peter D. Sly Tags: Original Article: Diagnostic Testing Source Type: research

Efficacy of palivizumab prophylaxis among infants with congenital heart disease: A case control study
ConclusionOur findings revealed significantly lower rate of overall and complicated LRTIs, LRTI‐related hospitalization and ICU admissions in infants with CHD via palivizumab prophylaxis. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - August 25, 2014 Category: Respiratory Medicine Authors: Abdullah Ozyurt, Nazmi Narin, Ali Baykan, Mustafa Argun, Ozge Pamukcu, Gokmen Zararsiz, Suleyman Sunkak, Kazim Uzum Tags: Original Article: Respiratory Infections Source Type: research

Clinical application of nasal nitric oxide measurement in pediatric airway diseases
Summary Nitric oxide plays an important role in several physiological and pathophysiological processes in the respiratory tract. Different ways to measure nasal nitric oxide levels in children are currently available. The possibility of obtaining nasal nitric oxide measurement from relatively young children, combined with the availability of portable devices that can be used even in the office setting, opens new perspectives for nasal nitric oxide analysis in the pediatric daily practice. This review presents a synopsis about the current clinical applications of nasal nitric oxide measurement in the pediatric clinical prac...
Source: Pediatric Pulmonology - August 25, 2014 Category: Respiratory Medicine Authors: Angelo Manna, Silvia Montella, Mauro Maniscalco, Marco Maglione, Francesca Santamaria Tags: Review: Translation Source Type: research

A molecular atlas of Xenopus respiratory system development
Conclusions: We demonstrate that Xenopus trachea and lung development, before metamorphosis, is comparable at the cellular and molecular levels to embryonic stages of mouse respiratory system development between E8.5 to E10.5. This molecular atlas provides a fundamental starting point for further studies using Xenopus as a model to define the conserved genetic programs controlling early respiratory system development. Developmental Dynamics, 2014. © 2014 Wiley Periodicals, Inc. (Source: Developmental Dynamics)
Source: Developmental Dynamics - August 25, 2014 Category: Molecular Biology Authors: Scott A. Rankin, Hong Thi Tran, Marcin Wlizla, Pamela Mancini, Emily T. Shifley, Sean D. Bloor, Lu Han, Kris Vleminckx, Susan E. Wert, Aaron M. Zorn Tags: Patterns & Phenotypes Source Type: research

Etiology and outcomes for patients infected with HIV in intensive care units in a tertiary care hospital in China
The objective for this study was to investigate the etiology and outcomes of patients infected with HIV admitted to intensive care units in Ditan Hospital, China. The evaluation of the etiology and outcomes of patients infected with HIV admitted to intensive care units was conducted using the clinical data from 122 patients infected with HIV (129 occasions) admitted to the Beijing Ditan hospital from January 1, 2009, to October 1, 2013. Over the five‐year study period, 129 occasions occurred for 122 patients infected with HIV admitted to intensive care units. Respiratory failure was the most common condition (53.4%) amon...
Source: Journal of Medical Virology - August 25, 2014 Category: Virology Authors: Jiang Xiao, Wen Zhang, Yingxiu Huang, Yunfei Tian, Wenjing Su, Yanmei Li, Wei Zhang, Ning Han, Di Yang, Hongxin Zhao Tags: Research Article Source Type: research

Impact of a Rapid Respiratory Panel Test on Patient Outcomes.
Conclusion .- The RRP decreases the duration of antibiotic use, the length of inpatient stay, and the time in isolation. PMID: 25152311 [PubMed - as supplied by publisher] (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - August 25, 2014 Category: Laboratory Medicine Authors: Rogers BB, Shankar P, Jerris RC, Kotzbauer D, Anderson EJ, Watson JR, O'Brien LA, Uwindatwa F, McNamara K, Bost JE Tags: Arch Pathol Lab Med Source Type: research

VIP Pipes Up: Neuronal Signals Direct Tubulogenesis.
Abstract Biological tubes serve as the body's plumbing system, transporting fluids and gases throughout secretory, circulatory, and respiratory organs. In this issue of Developmental Cell, Nedvetsky et al. (2014) find that vasoactive intestinal peptide (VIP), secreted by parasympathetic nerves, is a surprising player in directing epithelial tubulogenesis in salivary glands. PMID: 25158849 [PubMed - as supplied by publisher] (Source: Developmental Cell)
Source: Developmental Cell - August 25, 2014 Category: Cytology Authors: Houtz J, Kuruvilla R Tags: Dev Cell Source Type: research

The Nasal Complex of Neanderthals: An entry portal to their place in human ancestry
This study performs quantitative and qualitative analysis of aspects of the nasal complex (NC) in Neanderthals and other later Pleistocene fossils from Europe and Africa. A geographically diverse sample of modern human crania was used to establish an anatomical baseline for populations inhabiting cold and tropical climates. Nasofrontal angle, piriform aperture dimensions, and relative maxillary sinus volume were analyzed along with qualitative features of the piriform aperture rim. Results indicate that Neanderthals and other later Pleistocene Homo possessed NC’s that align them with tropical modern humans. Thus comparis...
Source: The Anatomical Record Part B: The New Anatomist - August 24, 2014 Category: Anatomy Authors: Samuel Márquez, Anthony S. Pagano, Eric Delson, William Lawson, Jeffrey T. Laitman Tags: Special Issue Article Source Type: research

Diagnostic Characteristics of a Clinical Screening Tool in Combination With Measuring Bedside Lactate Level in Emergency Department Patients With Suspected Sepsis / Características Diagnósticas de una Herramienta de Despistaje Clínico en Combinación con la Medición del Lactato a Pie de Cama en Pacientes con Sospecha de Sepsis en el Servicio de Urgencias
ConclusionsUse of a clinical screening tool in combination with early bedside POC lactates has moderate to good specificity but low sensitivity in adult ED patients with suspected sepsis. Elevated bedside lactate levels are associated with poor outcomes. Resumen AntecedentesLa identificación precoz de la sepsis y el inicio de un tratamiento enérgico salva vidas. Sin embargo, el diagnóstico de sepsis puede retrasarse en pacientes sin gran deterioro. Las herramientas de despistaje clínico y los valores séricos de lactato quizá puedan ayudar a identificar a los pacientes sépticos con riesgo de resultados adversos. Obj...
Source: Academic Emergency Medicine - August 24, 2014 Category: Emergency Medicine Authors: Adam J. Singer, Merry Taylor, Anna Domingo, Saad Ghazipura, Adam Khorasonchi, Henry C. Thode, Nathan I. Shapiro Tags: Original Contribution Source Type: research

Epithelium‐dependent profibrotic milieu in the pathogenesis of idiopathic pulmonary fibrosis: current status and future directions
ConclusionsEpithelium‐dependent profibrotic milieu formation and mesenchymal activation is the current view on the pathogenesis of IPF. New evidence from more analogous animal models may emerge and shift our thinking to a new and more faithful concept in the future. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - August 24, 2014 Category: Respiratory Medicine Authors: Xuefeng Xu, Huaping Dai, Chen Wang Tags: Review Article Source Type: research

Spongiivirga citrea gen. nov., sp. nov., a New Marine Bacterium of the Family Flavobacteriaceae Isolated from a Marine Sponge.
Abstract A Gram-negative, strictly aerobic, lemon-yellow pigmented, non-motile, rod-shaped strain designated A7G-39(T) was isolated from a yellow coloured marine sponge (Tethya sp.). Phylogenetic analyses based on the 16S rRNA gene sequence indicated that the new strain represented a member of the family Flavobacteriaceae of the phylum Bacteroidetes and that it showed highest sequence similarity (94.1 %) to Algibacter wandonensis WS-MY22(T). The strain could be differentiated phenotypically from recognised members of the family Flavobacteriaceae. The major fatty acids of strain A7G-39(T) were identified as iso-C15...
Source: Current Microbiology - August 24, 2014 Category: Microbiology Authors: Yoon J, Adachi K, Kasai H, Lee MK Tags: Curr Microbiol Source Type: research

Diagnostic Characteristics of a Clinical Screening Tool in Combination With Measuring Bedside Lactate Level in Emergency Department Patients With Suspected Sepsis.
CONCLUSIONS: Use of a clinical screening tool in combination with early bedside POC lactates has moderate to good specificity but low sensitivity in adult ED patients with suspected sepsis. Elevated bedside lactate levels are associated with poor outcomes. PMID: 25155163 [PubMed - as supplied by publisher] (Source: Accident and Emergency Nursing)
Source: Accident and Emergency Nursing - August 24, 2014 Category: Emergency Medicine Authors: Singer AJ, Taylor M, Domingo A, Ghazipura S, Khorasonchi A, Thode HC, Shapiro NI Tags: Acad Emerg Med Source Type: research

Efficacy and Safety of Early Dexmedetomidine During Noninvasive Ventilation for Patients With Acute Respiratory Failure: A Randomized, Double-Blind, Placebo-Controlled Pilot Study
Dexmedetomidine is a short-acting intravenous agent that provides cooperative sedation without affecting respiratory drive. This two-center prospective, randomized, double-blind, placebo-controlled study evaluated the use of dexmedetomidine for noninvasive ventilation in patients with acute respiratory failure (ARF). (Source: The Journal of Emergency Medicine)
Source: The Journal of Emergency Medicine - August 23, 2014 Category: Emergency Medicine Authors: Stephanie Oberfoell Tags: Abstracts Source Type: research

Antihistamine medication may alleviate negative effects of prenatal exposure to polycyclic aromatic hydrocarbons (PAH) on lung function in children. Birth cohort prospective study
Summary The main purpose of the present study was to test the hypothesis that the depressed lung growth attributable to prenatal exposure to polycyclic aromatic hydrocarbons (PAH) may be modified by the intake of antihistamine medications. Individual prenatal PAH exposure was assessed by personal air monitoring in 176 children who were followed over nine years, in the course of which outdoor residential air monitoring, allergic skin tests for indoor allergens, lung function tests (FVC, FEV1, FEV05, and FEF25‐75) were performed. The analysis with the General Estimated Equation (GEE) showed no association between prenatal ...
Source: Pediatric Pulmonology - August 23, 2014 Category: Respiratory Medicine Authors: Wieslaw A. Jedrychowski, Frederica P. Perera, Umberto Maugeri, Renata Majewska, Jack Spengler, Elzbieta Mroz, Elzbieta Flak, Maria Klimaszewska‐Rembiasz, David Camman Tags: Original Article: Epidemiolog Source Type: research

Identification of a gene, FMP21, whose expression levels are involved in thermotolerance in Saccharomyces cerevisiae
In conclusion, the function of Fmp21 is important for thermotolerance in yeasts. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - August 23, 2014 Category: Epidemiology Authors: Toshihide NakamuraMami YamamotoKatsuichi SaitoAkira AndoJun Shima Source Type: research

[Series] The role of the microbiome in exacerbations of chronic lung diseases
Culture-independent microbiological techniques have shown a previously unappreciated complexity to the bacterial microbiome of the respiratory tract that forces reconsideration of the interactions between host, bacteria, and the pathogenesis of exacerbations of chronic lung disease. The composition of the lung microbiome is determined by microbial immigration, elimination, and relative growth rates of its members. All these factors change dramatically in chronic lung disease and further during exacerbations. (Source: LANCET)
Source: LANCET - August 23, 2014 Category: Journals (General) Authors: Robert P Dickson, Fernando J Martinez, Gary B Huffnagle Tags: Series Source Type: research

[Series] Antimicrobial resistance in the respiratory microbiota of people with cystic fibrosis
Cystic fibrosis is characterised by chronic polymicrobial infection and inflammation in the airways of patients. Antibiotic treatment regimens, targeting recognised pathogens, have substantially contributed to increased life expectancy of patients with this disease. Although the emergence of antimicrobial resistance and selection of highly antibiotic-resistant bacterial strains is of major concern, the clinical relevance in cystic fibrosis is yet to be defined. Resistance has been identified in recognised cystic fibrosis pathogens and in other bacteria (eg, Prevotella and Streptococcus spp) detected in the airway microbiot...
Source: LANCET - August 23, 2014 Category: Journals (General) Authors: Laura J Sherrard, Michael M Tunney, J Stuart Elborn Tags: Series Source Type: research

Impact of oxygen concentration on time to resolution of spontaneous pneumothorax in term infants: a population based cohort study
Conclusions: Supplemental oxygen use or nitrogen washout was not associated with faster resolution of SP. Infants treated with room air remained stable and did not require supplemental oxygen at any point of their admission. (Source: BMC Pediatrics - Latest articles)
Source: BMC Pediatrics - Latest articles - August 23, 2014 Category: Pediatrics Authors: Huma ShaireenYacov RabiAmy MetcalfeMajeeda KamaluddeenHarish AminAlbert AkiermanAbhay Lodha Source Type: research