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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 5.

Forensic analysis of online marketing for electronic nicotine delivery systems
Conclusions These findings support increased monitoring and regulation of ENDS marketing to prevent deceptive marketing tactics and ensure consumer safety. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Cobb, N. K., Brookover, J., Cobb, C. O. Tags: Brief report Source Type: research

Adult smokers' receptivity to a television advert for electronic nicotine delivery systems
Conclusions Smokers are receptive to ENDS television adverts and report intention to try ENDS after viewing the advert. Future studies should monitor ENDS advertising and examine how exposure to ENDS adverts influences smokers’ use of ENDS, dual use with cigarettes and cessation behaviour. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Kim, A. E., Lee, Y. O., Shafer, P., Nonnemaker, J., Makarenko, O. Tags: Brief report Source Type: research

Applying linguistic methods to understanding smoking-related conversations on Twitter
Conclusions People are talking about tobacco-related issues on Twitter, and semantic network analysis can be used to characterise on-line conversations. Future interventions may be able to harness social media and major current events to raise awareness of smoking-related issues. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Sanders-Jackson, A., Brown, C. G., Prochaska, J. J. Tags: Brief report Source Type: research

What will it take to get to under 5% smoking prevalence by 2025? Modelling in a country with a smokefree goal
Conclusions The smokefree goal of <5% prevalence is only feasible with large increases in cessation rates. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Ikeda, T., Cobiac, L., Wilson, N., Carter, K., Blakely, T. Tags: Editor's choice Research paper Source Type: research

Youth exposure to in-vehicle second-hand smoke and their smoking behaviours: trends and associations in repeated national surveys (2006-2012)
Conclusions The slow decline in SHS exposure in vehicles and the lack of progress in reducing relative inequalities is problematic. To accelerate progress, the New Zealand Government could follow the example of other jurisdictions and prohibit smoking in cars carrying children. Other major policy interventions, beside enhanced smoke-free environments, will also likely be required if New Zealand is to achieve its 2025 smoke-free nation goal. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Healey, B., Hoek, J., Wilson, N., Thomson, G., Taylor, S., Edwards, R. Tags: Research paper Source Type: research

Using a new, low-cost air quality sensor to quantify second-hand smoke (SHS) levels in homes
Conclusions The Dylos appears to be a valid instrument for measuring PM2.5 in household settings. The Dylos may be useful in air quality-based interventions designed to change smokers’ behaviours with the possibility of encouraging cessation and/or smoke-free homes. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Semple, S., Ibrahim, A. E., Apsley, A., Steiner, M., Turner, S. Tags: Research paper Source Type: research

Pro-smoking apps: where, how and who are most at risk
Conclusions Pro-smoking apps were popular in many countries. Most apps were assigned to entertainment and games categories, with some apps specifically targeting children through placement in categories directed at children. App stores that feature pro-smoking apps may be in violation of tobacco control laws. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: BinDhim, N. F., Freeman, B., Trevena, L. Tags: Research paper Source Type: research

The tobacco endgame in Hong Kong: public support for a total ban on tobacco sales
Conclusions A total ban on tobacco sales was supported by most respondents. Ex-smokers and current smokers also voiced substantial support, although less than never smokers. A total ban on tobacco sales before 2022 should be the goal as it is supported by most of the respondents. Interim tobacco control measures, such as tax increases, expansion of smoking cessation services and plain packaging should be implemented to help current smokers quit and reduce smoking initiation before implementation of the ban. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Wang, M. P., Wang, X., Lam, T. H., Viswanath, K., Chan, S. S. Tags: Research paper Source Type: research

Association between clean indoor air laws and voluntary smokefree rules in homes and cars
Conclusions Clean indoor air laws provide the additional benefit of encouraging voluntary adoption of smokefree rules in homes and cars. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Cheng, K.-W., Okechukwu, C. A., McMillen, R., Glantz, S. A. Tags: Research paper Source Type: research

'Enter at your own risk': a multimethod study of air quality and biological measures in Canadian waterpipe cafes
Conclusions Staff and patrons of waterpipe cafes are exposed to air quality levels considered hazardous to human health. Results support eliminating waterpipe smoking in hospitality venues indoors and out. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Zhang, B., Haji, F., Kaufman, P., Muir, S., Ferrence, R. Tags: Research paper Source Type: research

Understanding the emergence of the tobacco industry's use of the term tobacco harm reduction in order to inform public health policy
Conclusions Transnational tobacco companies’ harm reduction discourse should be seen as opportunistic tactical adaptation to policy change rather than a genuine commitment to harm reduction. Care should be taken that this does not undermine gains hitherto secured in efforts to reduce the ability of the tobacco industry to inappropriately influence policy. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Peeters, S., Gilmore, A. B. Tags: Open access Research paper Source Type: research

Smoking status, nicotine dependence and happiness in nine countries of the former Soviet Union
Conclusions This study contradicts the idea that smoking is associated with greater happiness. Moreover, of relevance for policy in the fSU countries, given the lack of public knowledge about the detrimental effects of smoking on health but widespread desire to quit reported in recent research, the finding that smoking is associated with lower levels of happiness should be incorporated in future public health efforts to help encourage smokers to quit by highlighting that smoking cessation may result in better physical and emotional health. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Stickley, A., Koyanagi, A., Roberts, B., Leinsalu, M., Goryakin, Y., McKee, M. Tags: Research paper Source Type: research

What is the role of tobacco control advertising intensity and duration in reducing adolescent smoking prevalence? Findings from 16 years of tobacco control mass media advertising in Australia
Conclusions Both antismoking advertising intensity and duration are important for ensuring reductions in adolescent smoking prevalence. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: White, V. M., Durkin, S. J., Coomber, K., Wakefield, M. A. Tags: Research paper Source Type: research

The cost of secondhand smoke exposure at home in California
Conclusions The economic impact of SHS exposure in the home totalled $360 million in California in 2009. Policies that reduce exposure to SHS at home have great potential for reducing healthcare and mortality costs. (Source: Tobacco Control)
Source: Tobacco Control - February 20, 2015 Category: Respiratory Medicine Authors: Max, W., Sung, H.-Y., Shi, Y. Tags: Research paper Source Type: research

The impact of changing people with sleep apnoea using CPAP less than 4 hours per night to a Bi-level device
Pressure intolerance is a reason for poor acceptance and subsequent compliance in some patients starting treatment with continuous positive airway pressure (CPAP). In unselected populations initiating CPAP; different types of pressure generating device have not been found to improve compliance. We hypothesized that using Bi-level PAP for patients who reported pressure related discomfort as a cause for poor compliance with CPAP might increase their hours of treatment use.Patients using CPAP (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 20, 2015 Category: Respiratory Medicine Authors: Atul Gulati, Nicholas Oscroft, Rebecca Chadwick, Masood Ali, Ian Smith Source Type: research

Tuberculosis screening and compliance rate with guidelines among Northern Portuguese Hospitals prescribers of anti-TNF therapy
Publication date: Available online 18 February 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): B.A. Ferreira , S. Ribeiro , J. Meireles , A. Correia , R. Duarte (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Combined intrapleural therapy in infectious pleural effusion
Publication date: Available online 18 February 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): H. Dabó , L. Meira , I. Neves , A. Marinho , I. Gomes (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Oxygen therapy: a clinical audit in an Internal Medicine Department
Publication date: Available online 18 February 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): S. Nunes , J. Maia , J.P. Ferreira , J. Neves , I. Marques (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Solitary fibrous tumors of the pleura: not always a benign entity
Publication date: Available online 18 February 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): L.M. Nascimento , T. Gomes , A. Fernandes , A. Afonso (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Pulmonary function, functional capacity and quality of life in adults with cystic fibrosis
Conclusion Adults with CF have reduced quality of life, which in part is associated with the severity of their lung function. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Respiratory parameters in elite athletes – does sport have an influence?
Conclusion The study suggests that specific type of training used in basketball, water polo or rowing could have potential for improving pulmonary function and rehabilitation. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

The value of cough peak flow measurements in the assessment of extubation or decannulation readiness
Publication date: Available online 13 February 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): J.C. Winck , C. LeBlanc , J.L. Soto , F. Plano Insufficient cough strength has a major role in extubation and decannulation outcomes. Cough capacity can be easily evaluated by measuring flows during coughing. Values vary depending on whether cough flows are measured through the mouth or through a tracheostomy or endotracheal tube. It is important to standardize these measurements and start using them routinely in the extubation and decannulation processes. Values of cough peak flow &gt;160L/min me...
Source: Revista Portuguesa de Pneumologia - February 20, 2015 Category: Respiratory Medicine Source Type: research

Fibromyalgia‐like symptoms associated with irritable bowel syndrome: A challenging diagnosis of late‐onset Pompe disease
CONCLUSIONS: Clinicians should be aware of this atypical presentation of LOPD to enable earlier diagnosis and treatment. This article is protected by copyright. All rights reserved. (Source: Muscle and Nerve)
Source: Muscle and Nerve - February 20, 2015 Category: Internal Medicine Authors: Aude Gesquière‐Dando, Shahram Attarian, André Maues de Paula, Jean Pouget, Emmanuelle Salort‐Campana Tags: Case of the Month Source Type: research

Neonatal mitochondrial hepatoencephalopathy caused by novel GFM1 mutations
Publication date: June 2015 Source:Molecular Genetics and Metabolism Reports, Volume 3 Author(s): Kirstine Ravn , Bitten Schönewolf-Greulich , Rikke M. Hansen , Anna-Helene Bohr , Morten Duno , Flemming Wibrand , Elsebet Ostergaard Disorders caused by defects in the mitochondrial translation system are clinically and genetically heterogeneous. The elongation phase of mitochondrial protein synthesis requires, among many other components, three nuclear-encoded elongation factors: EFTu (TUFM; 602389), EFTs (TSFM; 604723), and EFG1 (GFM1; 606639). Mutations have been identified in the genes encoding all three elongation fac...
Source: Molecular Genetics and Metabolism Reports - February 20, 2015 Category: Genetics & Stem Cells Source Type: research

Superior vena cava drainage improves upper body oxygenation during veno-arterial extracorporeal membrane oxygenation in sheep
Conclusions: Differential venous oxygen return is a key factor in the aetiology of differential hypoxia in VA ECMO. With knowledge of this mechanism, we can apply better cannula configurations in clinical practice. (Source: Critical Care)
Source: Critical Care - February 20, 2015 Category: Intensive Care Authors: Xiaotong HouXiaofang YangZhongtao DuJialin XingHui LiChunjing JiangJinhong WangZhichen XingShuanglei LiXiaokui LiFeng YangHong WangHui Zeng Source Type: research

The Polysaccharide Capsule of Streptococcus pneumonia Partially Impedes MyD88-Mediated Immunity during Pneumonia in Mice
by Alex F. de Vos, Mark C. Dessing, Adriana J. J. Lammers, Alexander P. N. A. de Porto, Sandrine Florquin, Onno J. de Boer, Regina de Beer, Sanne Terpstra, Hester J. Bootsma, Peter W. Hermans, Cornelis van ‘t Veer, Tom van der Poll Toll-like receptors (TLR) and the downstream adaptor protein MyD88 are considered crucial for protective immunity during bacterial infections. Streptococcus (S.) pneumoniae is a human respiratory pathogen and a large majority of clinical pneumococcal isolates expresses an external polysaccharide capsule. We here sought to determine the role of pneumococcal capsule in MyD88-mediated antibacter...
Source: PLoS One - February 20, 2015 Category: Biomedical Science Authors: Alex F. de Vos et al. Source Type: research

The Nucleocapsid Protein of Human Coronavirus NL63
by Kaja Zuwała, Anna Golda, Wojciech Kabala, Michał Burmistrz, Michal Zdzalik, Paulina Nowak, Sylwia Kedracka-Krok, Mirosław Zarebski, Jerzy Dobrucki, Dominik Florek, Sławomir Zeglen, Jacek Wojarski, Jan Potempa, Grzegorz Dubin, Krzysztof Pyrc Human coronavirus (HCoV) NL63 was first described in 2004 and is associated with respiratory tract disease of varying severity. At the genetic and structural level, HCoV-NL63 is similar to other members of the Coronavirinae subfamily, especially human coronavirus 229E (HCoV-229E). Detailed analysis, however, reveals several unique features of the pathogen. The coronaviral nucleo...
Source: PLoS One - February 20, 2015 Category: Biomedical Science Authors: Kaja Zuwała et al. Source Type: research

Time-invariant measurement of time-varying bioimpedance using vector impedance analysis
When stepped-sine impedance spectroscopy measurements are carried out on (periodically) time-varying bio-systems, the inherent time-variant (time-periodic) parts are traditionally ignored or mitigated by filtering. The latter, however, lacks theoretical foundation and, in this paper, it is shown that it only works under certain specific conditions. Besides, we propose an alternative method, based on multisine signals, that exploits the non-stationary nature in time-varying bio-systems with a dominant periodic character, such as cardiovascular and respiratory systems, or measurements interfered with by their physiolog...
Source: Physiological Measurement - February 20, 2015 Category: Physiology Authors: B Sanchez, E Louarroudi and R Pintelon Source Type: research

Erratum: Measuring dissimilarity between respiratory effort signals based on uniform scaling for sleep staging (2014 Physiol. Meas. 35 2539)
Description unavailable (Source: Physiological Measurement)
Source: Physiological Measurement - February 20, 2015 Category: Physiology Authors: Xi Long, Jie Yang, Tim Weysen, Reinder Haakma, J?r?me Foussier, Pedro Fonseca and Ronald M Aarts Source Type: research

Influence of orally administered Lactobacillus GG on respiratory immune response in a murine model of diet‐induced obesity
ABSTRACT Mice with diet‐induced obesity were fed with Lactobacillus rhamnosus GG (LGG) suspended in saline or saline alone (control mice). Pulmonary mRNA expression of IFN‐γ; IFN‐α receptor 1; CD247 antigen; killer cell lectin‐like receptor subfamily K, member 1; TNF‐α; IL‐12 receptor β1 and IL‐2 receptor β, and the proportion of Lactobacillales in feces were significantly greater in the LGG group than in the control mice (P < 0.05 and P < 0.01, respectively). These results suggest that LGG alters the respiratory immunity of obese subjects through having a potent impact on intestinal immuni...
Source: Microbiology and Immunology - February 20, 2015 Category: Microbiology Authors: Kenji Miyazawa, Kazutoyo Yoda, Manabu Kawase, Gaku Harata, Fang He Tags: Note Source Type: research

Gua Sha a traditional Chinese healing technique that could mimick physical abuse: a potential issue with forensic implications. A case study
Gua Sha (press-stroking) is a traditional Chinese healing technique utilized to combat pain, the common cold, heatstroke, and respiratory problems. Patterned ecchymosis may appear due to the action of scraping and scratching repeatedly and in a unidirectional manner, with a smooth edge over a lubricated area [1]. The petechiae readily fade to ecchymosis that resolves completely within several days. Gua Sha literally means “scratch the sand” [1]. (Source: Forensic Science International)
Source: Forensic Science International - February 20, 2015 Category: Forensic Medicine Authors: A. Aprile, C. Pomara, E. Turillazzi Tags: Case Report Source Type: research

Factors that predict in‐hospital mortality in eosinophilic granulomatosis with polyangiitis
ConclusionsOur study revealed the clinical features of EGPA patients who required hospitalization and the factors associated with their mortality. These results may be useful for physicians when assessing disease severity or treatments for hospitalized EGPA patients.This article is protected by copyright. All rights reserved. (Source: Allergy)
Source: Allergy - February 20, 2015 Category: Allergy & Immunology Authors: Wakae Hasegawa, Yasuhiro Yamauchi, Hideo Yasunaga, Mitsuhiro Sunohara, Taisuke Jo, Hiroki Matsui, Kiyohide Fushimi, Kazutaka Takami, Takahide Nagase Tags: Original Article: Autoimmune Diseases Source Type: research

Surfactant Protein A Expression in Chronic Rhinosinusitis and Atrophic Rhinitis
Conclusion SP-A is significantly increased in CRS and decreased significantly in PAR and appears to be expressed by respiratory epithelial cells and submucosal glandular elements of the sinonasal mucosa. The potential therapeutic applications of surfactant in the enhancement of mucociliary clearance need to be studied.[...]Thieme Publicações Ltda Rio de Janeiro, BrazilArticle in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: International Archives of Otorhinolaryngology)
Source: International Archives of Otorhinolaryngology - February 20, 2015 Category: ENT & OMF Authors: El-Anwar, Mohammad WaheedHamed, Atef A.Mohamed, Abd ElRaof SaidNofal, Ahmad Abdel-FattahMohamed, Maha A.Abdel-Aziz, Hesham R. Tags: Original Research Source Type: research

Panayiotopoulos syndrome presenting with respiratory arrest: A case report and literature review
We describe a child with Panayiotopoulos syndrome (PS) who presented with autonomic status epilepticus and developed respiratory arrest requiring intubation and mechanical ventilation. Because of that life-threatening episode and the risk of developing a similar event in subsequent seizures, we decided to initiate our patient on AED treatment. Such life-threatening complications were previously reported in only four children with PS. Although PS is considered to be a benign childhood epilepsy syndrome usually not requiring treatment with antiepileptic drugs, our case and the small number of similar cases in the literature ...
Source: Epilepsy and Behavior Case Reports - February 20, 2015 Category: Neurology Source Type: research

Designs of two randomized, community-based trials to assess the impact of influenza immunization during pregnancy on respiratory illness among pregnant women and their infants and reproductive outcomes in Rural Nepal
DiscussionWe have presented the design and methods of two randomized trials of influenza immunization of pregnant women.Trial registrationClinicaltrials.gov: (NCT01034254). (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - February 20, 2015 Category: OBGYN Authors: James TielschMark SteinhoffJoanne KatzJanet EnglundJane KuypersSubarna KhatryLaxman ShresthaSteven LeClerq Source Type: research

Airflow obstruction case finding in community- pharmacies: A NOVEL strategy to reduce COPD underdiagnosis
Community pharmacies (CP) have access to subjects at high-risk of suffering Chronic Obstructive Pulmonary Disease (COPD). We investigated if a COPD case finding program in CP could be a new strategy to reduce COPD underdiagnosis. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - February 20, 2015 Category: Respiratory Medicine Authors: D. Castillo, F. Burgos, R. Guayta, J. Giner, P. Lozano, M. Estrada, J.B. Soriano, X. Flor, M. Barau, P. Casan, the FARMAEPOC group Source Type: research

Physiological Responses during Cycle Ergometry at a Constant Perception of Effort
Int J Sports MedDOI: 10.1055/s-0034-139682613 subjects performed an incremental test to exhaustion, 4, 8-min submaximal rides, and a 1-h ride at the rating of perceived exertion (RPE) that corresponded to the physical working capacity at the OMNI threshold (PWCOMNI) to examine: 1) the oxygen consumption (V̇O2), heart rate (HR), minute ventilation (+V̇ E ), respiratory frequency (FR), and power output responses during 1-h work bouts at a constant RPE that corresponded to the PWCOMNI; and 2) the ability of current models to explain the responses for physiological and perceptual parameters during the 1-h work bouts. The RPE...
Source: International Journal of Sports Medicine - February 20, 2015 Category: Sports Medicine Authors: Cochrane, K. C.Housh, T. J.Bergstrom, H. C.Jenkins, N. D. M.Johnson, G.Schmidt, R. J.Cramer, J. T. Tags: Training & Testing Source Type: research

Facial Video-Based Photoplethysmography to Detect HRV at Rest
Int J Sports MedDOI: 10.1055/s-0034-1398530Our aim is to demonstrate the usefulness of photoplethysmography (PPG) for analyzing heart rate variability (HRV) using a standard 5-min test at rest with paced breathing, comparing the results with real RR intervals and testing supine and sitting positions. Simultaneous recordings of R–R intervals were conducted with a Polar system and a non-contact PPG, based on facial video recording on 20 individuals. Data analysis and editing were performed with individually designated software for each instrument. Agreement on HRV parameters was assessed with concordance correlations, effe...
Source: International Journal of Sports Medicine - February 20, 2015 Category: Sports Medicine Authors: Moreno, J.Ramos-Castro, J.Movellan, J.Parrado, E.Rodas, G.Capdevila, L. Tags: Training & Testing Source Type: research

Anaerosolibacter carboniphilus gen. nov., sp. nov., a strictly anaerobic iron-reducing bacterium isolated from a coal-contaminated soil.
Abstract A strictly anaerobic, mesophilic, iron-reducing bacterial strain IRF19T was isolated from coal-contaminated soil in the Republic of Korea. IRF19T cells were straight, rod-shaped, Gram-staining negative and motile by flagella. The optimum pH and temperature for their growth were determined to be 7.5-8.0 and 40 °C, while the optimum range was 6.5-10.0 and 20-45 °C, respectively. Strain IRF19T did not require NaCl for their growth but it tolerated up to 2 % (w/v). Growth was observed with yeast extract, D-glucose, D-fructose, D-ribose, D-mannitol, D-mannose, L-serine, L-alanine, and L-isoleucine. Fe(III), e...
Source: International Journal of Systematic and Evolutionary Microbiology - February 20, 2015 Category: Microbiology Authors: Hong H, Kim SJ, Min UG, Lee YJ, Kim SG, Roh SW, Kim JG, Na JG, Rhee SK Tags: Int J Syst Evol Microbiol Source Type: research

Marivirga atlantica sp. nov., isolated from seawater of the Atlantic Ocean and emended description of the genus Marivirga.
Abstract A novel Gram-negative, aerobic, orange-pigmented, non-flagellated, gliding, rod-shaped bacterium, designated strain SM1354T, was isolated from surface seawater of the Atlantic Ocean. The strain hydrolyzed gelatin and DNA but did not reduce nitrate. It grew at 4-40 oC and with 0.5-11 % NaCl. Phylogenetic analysis of the 16S rRNA gene sequences revealed that strain SM1354T belonged to the genus Marivirga with 96.0~96.2 % sequence similarities to known Marivirga species. The major fatty acids of strain SM1354T were iso-C15:0, iso-C15:1 G, iso-C17:03-OH and summed feature 3 (C16:1ω7c and/or iso-C15:02-OH). Po...
Source: International Journal of Systematic and Evolutionary Microbiology - February 20, 2015 Category: Microbiology Authors: Lin CY, Zhang XY, Liu A, Liu C, Song XY, Su HN, Qin QL, Xie BB, Zhang YZ Tags: Int J Syst Evol Microbiol Source Type: research

Interaction of SFS with Fibronectin [Protein Structure and Folding]
SFS is a non-anchored protein of Streptococcus equi subspecies equi that causes upper respiratory infection in horses. SFS has been shown to bind to fibronectin (FN) and block interaction of FN with type I collagen. We have characterized interactions of a recombinant 60-mer polypeptide, R1R2, with FN. R1R2 contains two copies of collagen-like 19-residue repeats. Experiments utilizing various FN fragments and epitope-mapped anti-FN monoclonal antibodies located the binding site to 8-9FNI modules of the gelatin-binding domain. Fluorescence polarization and competitive enzyme-linked assays demonstrated that R1R2 binds prefere...
Source: Journal of Biological Chemistry - February 20, 2015 Category: Chemistry Authors: Ma, W., Ma, H., Fogerty, F. J., Mosher, D. F. Tags: Glycobiology and Extracellular Matrices Source Type: research

NLRP3 Contributes to HALI Independent of IL-1{beta} [Immunology]
In this study, we investigated the role of NLRP3 inflammasomes in mice with HALI. Under hyperoxic conditions, NLRP3−/− mice died at a higher rate compared with wild-type and IL-1β−/− mice, and there was no difference in IL-1β production in their lungs. Under hyperoxic conditions, the lungs of NLRP3−/− mice exhibited reduced inflammatory responses, such as inflammatory cell infiltration and cytokine expression, as well as increased and decreased expression of MMP-9 and Bcl-2, respectively. NLRP3−/− mice exhibited diminished expression and activation of Stat3, which regulates MMP-9 and Bcl-2, in addition to...
Source: Journal of Biological Chemistry - February 20, 2015 Category: Chemistry Authors: Mizushina, Y., Shirasuna, K., Usui, F., Karasawa, T., Kawashima, A., Kimura, H., Kobayashi, M., Komada, T., Inoue, Y., Mato, N., Yamasawa, H., Latz, E., Iwakura, Y., Kasahara, T., Bando, M., Sugiyama, Y., Takahashi, M. Tags: Molecular Bases of Disease Source Type: research

Barrier or carrier? Pulmonary surfactant and drug delivery.
Abstract To consider the lung as a target for drug delivery and to optimize strategies directed at the pulmonary route, it is essential to consider the role of pulmonary surfactant, a thin lipid-protein film lining the respiratory surface of mammalian lungs. Membrane-based surfactant multilayers are essential for reducing the surface tension at the respiratory air-liquid interface to minimize the work of breathing. Different components of surfactant are also responsible for facilitating the removal of potentially pathological entities such as microorganisms, allergens or environmental pollutants and particles. Upon...
Source: European Journal of Pharmaceutics and Biopharmaceutics - February 20, 2015 Category: Drugs & Pharmacology Authors: Hidalgo A, Cruz A, Perez-Gil J Tags: Eur J Pharm Biopharm Source Type: research

Awareness of COPD in a High Risk Korean Population.
CONCLUSION: We found that awareness of COPD is very poor among current smokers in Korea. Many smokers perceived their health status as good, despite the presence of COPD-related symptoms. As the level of smoking-cessation willingness was different between those with and without awareness of COPD or COPD-related symptoms, a personalized education program with various educational tools may be needed to enhance awareness of the disease and to motivate smokers to quit. PMID: 25683982 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - February 19, 2015 Category: Universities & Medical Training Authors: Seo JY, Hwang YI, Mun SY, Kim JH, Kim JH, Park SH, Jang SH, Park YB, Shim JJ, Jung KS Tags: Yonsei Med J Source Type: research

Efficacy of Surfactant-TA, Calfactant and Poractant Alfa for Preterm Infants with Respiratory Distress Syndrome: A Retrospective Study.
CONCLUSION: Calfactant is equally as effective as surfactant-TA and poractant alfa. This was the first study comparing the efficacy of surfactant-TA, calfactant, and poractant alfa in a large number of preterm infants in Korea. Further randomized prospective studies on these surfactants are needed. PMID: 25683992 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - February 19, 2015 Category: Universities & Medical Training Authors: Jeon GW, Oh M, Sin JB Tags: Yonsei Med J Source Type: research

Optimal Effect-Site Concentration of Remifentanil for Inhibiting Response to Laryngeal Mask Airway Removal during Emergence.
CONCLUSION: Maintaining a remifentanil Ce of 1.0 ng/mL during emergence may suppress adverse events such as coughing, breath-holding, and agitation following the removal of LMA without delayed awakening. PMID: 25684005 [PubMed - in process] (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - February 19, 2015 Category: Universities & Medical Training Authors: Park SJ, Baek JY, Jee DL Tags: Yonsei Med J Source Type: research