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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 6.

Pulmonary actinomycosis masquerading as lung cancer: Case letter
Moti Lal Bunkar, Prahlad Rai Gupta, Rajendra Takhar, Gajendra Singh Rajpoot, Savita AryaLung India 2016 33(4):460-462 (Source: Lung India)
Source: Lung India - June 29, 2016 Category: Respiratory Medicine Authors: Moti Lal BunkarPrahlad Rai GuptaRajendra TakharGajendra Singh RajpootSavita Arya Source Type: research

Septic lung metastasis in xanthogranulomatous pyelonephritis
Radha Sistla, Tameem Afroz, Sudhir Prasad, Ravindra Nallagonda, Raja PrasadLung India 2016 33(4):462-464 (Source: Lung India)
Source: Lung India - June 29, 2016 Category: Respiratory Medicine Authors: Radha SistlaTameem AfrozSudhir PrasadRavindra NallagondaRaja Prasad Source Type: research

Inter-hospital transport of severe acute respiratory distress syndrome on extracorporeal membrane oxygenation: Extracorporeal membrane oxygenation retrieval
Raj Kumar, Deepak VermaLung India 2016 33(4):465-467 (Source: Lung India)
Source: Lung India - June 29, 2016 Category: Respiratory Medicine Authors: Raj KumarDeepak Verma Source Type: research

Rheumatoid arthritis associated interstitial lung disease: 1 year is too much to exclude methotrexate-induced pulmonary involvement
Ashok Kuwal, Naveen Dutt, Nishant ChauhanLung India 2016 33(4):467-468 (Source: Lung India)
Source: Lung India - June 29, 2016 Category: Respiratory Medicine Authors: Ashok KuwalNaveen DuttNishant Chauhan Source Type: research

Pleural manometry: Relevance in today's practice
Rakesh K Chawla, Arun Madan, Aditya ChawlaLung India 2016 33(4):468-470 (Source: Lung India)
Source: Lung India - June 29, 2016 Category: Respiratory Medicine Authors: Rakesh K ChawlaArun MadanAditya Chawla Source Type: research

Chemotherapy regimens for metastatic nonsmall cell lung cancer: Generating good quality data is important before challenging evidence
Harpreet Kaur, Inderpaul Singh Sehgal, Navneet SinghLung India 2016 33(4):470-472 (Source: Lung India)
Source: Lung India - June 29, 2016 Category: Respiratory Medicine Authors: Harpreet KaurInderpaul Singh SehgalNavneet Singh Source Type: research

A rare case of rituximab induced interstitial lung disease
Kamal Kant Sahu, Prayas Badhala, Pankaj Malhotra, AN AggarwalLung India 2016 33(4):472-473 (Source: Lung India)
Source: Lung India - June 29, 2016 Category: Respiratory Medicine Authors: Kamal Kant SahuPrayas BadhalaPankaj MalhotraAN Aggarwal Source Type: research

Caverno-cutaneous fistula: A rare entity
Manoj Meena, Neeraj Gupta, Harish V Sabarigirivasan, Piyush Arora, Jai Prakash KewlaniLung India 2016 33(4):474-475 (Source: Lung India)
Source: Lung India - June 29, 2016 Category: Respiratory Medicine Authors: Manoj MeenaNeeraj GuptaHarish V SabarigirivasanPiyush AroraJai Prakash Kewlani Source Type: research

Book review: My experiment with Gandhi Marg
Jawahar TaunkLung India 2016 33(4):476-476 (Source: Lung India)
Source: Lung India - June 29, 2016 Category: Respiratory Medicine Authors: Jawahar Taunk Source Type: research

Microbiological findings in burn patients treated in a general versus a designated intensive care unit: Effect on length of stay
In burn patients, infections are one of the most common causes of mortality and morbidity [1–5]. Loss of the mechanical barrier of the skin, respiratory tract injury, the immune-compromising consequences of burns, prolonged hospital stays, and invasive diagnostic and therapeutic procedures increase susceptibility to infections [5,6]. During the long hospital stays of severely burnt patients, nosocomial infections are a challenging problem [7], especially because burn patients have higher rates of septicaemia with inferior outcome, ventilator-associated pneumonia, and wound infections compared to other intensive care pati...
Source: Burns : Journal of the International Society for Burn Injuries - June 29, 2016 Category: Cosmetic Surgery Authors: Andrea C. Issler-Fisher, Richard M Fakin, Oliver M Fisher, Genevieve McKew, Riccardo Gazzola, Ann-Kathrin Rauch, Thomas Gottlieb, Peter Haertsch, Merlin Guggenheim, Pietro Giovanoli, Peter K.M. Maitz Source Type: research

Looking Beyond Structure: Membrane Phospholipids of Skeletal Muscle Mitochondria
Publication date: Available online 28 June 2016 Source:Trends in Endocrinology & Metabolism Author(s): Timothy D. Heden, P. Darrell Neufer, Katsuhiko Funai Skeletal muscle mitochondria are highly dynamic and are capable of tremendous expansion to meet cellular energetic demands. Such proliferation in mitochondrial mass requires a synchronized supply of enzymes and structural phospholipids. While transcriptional regulation of mitochondrial enzymes has been extensively studied, there is limited information on how mitochondrial membrane lipids are generated in skeletal muscle. Herein we describe how each class of...
Source: Trends in Endocrinology and Metabolism - June 29, 2016 Category: Endocrinology Source Type: research

MmpL transporter-mediated export of cell-wall associated lipids and siderophores in mycobacteria
Mycobacteria produce a large variety of surface-exposed lipids with unusual structures. Some of these compounds are ubiquitously present in mycobacteria and play an important role in the structural organization of the cell envelope, while others are species-specific. The biosynthesis of most of these lipids requires modular polyketide synthases (PKS) or non-ribosomal peptide synthetases (NRPS) that are intracellular, suggesting that the assembly of these compounds takes place in the cytosolic compartment or near the inner leaflet of the plasma membrane. (Source: Tuberculosis)
Source: Tuberculosis - June 29, 2016 Category: Respiratory Medicine Authors: Christian Chalut Tags: Review Source Type: research

In-depth analysis of the genome sequence of a clinical, extensively drug-resistant Mycobacterium bovis strain
Although human-to-human transmission of Mycobacterium bovis strains and other members of the animal lineage of the tubercle bacilli is a rare event, an extensively drug resistant (XDR) strain, named M. bovis B strain, caused a lethal outbreak in the nineties in Spain. The genome of M. bovis B strain was re-sequenced by SOLiD platform and mapped to the reference M. bovis AF2122/97. The genetic polymorphisms detected have been analysed in depth.One hundred and fifty-eight specific non-synonymous SNPs were detected; ninety-two of these were non-conservative. (Source: Tuberculosis)
Source: Tuberculosis - June 29, 2016 Category: Respiratory Medicine Authors: Sara Sagasti, María Isabel Millán-Lou, María Soledad Jiménez, Carlos Martín, Sofía Samper Tags: Molecular Aspects Source Type: research

Neutrophil Extracellular Traps in Respiratory Disease: guided anti-microbial traps or toxic webs?
Neutrophil recruitment to the airways and lungs is a major hallmark of many respiratory diseases. One of the more recently discovered unique innate immune effector mechanisms of neutrophils is the formation of neutrophil extracellular traps (NETs), consisting of an extracellular network of DNA fibers studded with nuclear and granule proteins. Although in the respiratory system NETs contribute to capture and inactivation of bacteria, fungi and viruses, there is a delicate ‘balance’ between aid and damage to the host. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - June 29, 2016 Category: Respiratory Medicine Authors: B. Cortjens, J.B.M. van Woensel, R.A. Bem Source Type: research

Ambrisentan response in connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) – A subgroup analysis of the ARIES-E clinical trial
Pulmonary arterial hypertension (PAH) is a condition which may lead to right ventricular failure and early mortality and is an important complication in patients with connective tissue disease (CTD). Previously, the endothelin A selective receptor antagonist, ambrisentan, demonstrated efficacy and safety in treating patients with PAH due to WHO Group I etiologies. These analyses describe the 3-year efficacy and safety of ambrisentan in patients specifically with CTD associated PAH (CTD-PAH). (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - June 29, 2016 Category: Respiratory Medicine Authors: Aryeh Fischer, Christopher P. Denton, Marco Matucci-Cerinic, Hunter Gillies, Christiana Blair, James Tislow, Steven D. Nathan Source Type: research

Impact of hyponatremia on mortality and morbidity in patients with COPD exacerbations
Hyponatremia is the most common electrolyte disorder in hospitalized patients, being associated with increased morbidity and mortality in different clinical conditions. However, the prevalence and impact of this electrolytic disorder in patients hospitalized for an exacerbation of COPD still remains unknown. The aim of the present study was to clarify these points. A total of 424 patients hospitalized due to a COPD exacerbation were consecutively included, showing a frequency of hyponatremia of 15.8% (hyposmolar in most cases). (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - June 29, 2016 Category: Respiratory Medicine Authors: Roberto Chalela, José Gregorio González-García, Juan José Chillarón, Leticia Valera-Hernández, Carlos Montoya-Rangel, Diana Badenes, Sergi Mojal, Joaquim Gea Source Type: research

Effects of vagotomy on hypoglossal and phrenic responses to hypercapnia in the decerebrate rat
Publication date: October 2016 Source:Respiratory Physiology & Neurobiology, Volume 232 Author(s): Michael George Zaki Ghali, Vitaliy Marchenko Hypercapnia characterizes a variety of physiological and pathological states and must be compensated effectively by the respiratory, cardiovascular, renal, and intra- and extracellular pH buffering systems to maintain homeostasis. Several studies have examined the respiratory response to hypercapnia, but contemporaneous changes in respiratory frequency and tidal volume prevent investigating the pure influence on respiratory amplitude. Therefore, we sought to test the ef...
Source: Respiratory Physiology and Neurobiology - June 29, 2016 Category: Respiratory Medicine Source Type: research

Ultrasound for the Pulmonary Consultant
This article describes major applications of ultrasonography for the pulmonary consultant along with illustrative figures and videos. (Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine)
Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine - June 29, 2016 Category: Respiratory Medicine Authors: Astha ChichraMina MakaryusParag ChaudhriMangala Narasimhan Source Type: research

Constrained Allocation Flux Balance Analysis
by Matteo Mori, Terence Hwa, Olivier C. Martin, Andrea De Martino, Enzo Marinari New experimental results on bacterial growth inspire a novel top-down approach to study cell metabolism, combining mass balance and proteomic constraints to extend and complement Flux Balance Analysis. We introduce here Constrained Allocation Flux Balance Analysis, CAFBA, in which the biosynthetic costs associated to growth are accounted for in an effective way through a single additional genome-wide constraint. Its roots lie in the experimentally observed pattern of proteome allocation for metabolic functions, allowing to bridge regulation a...
Source: PLoS Computational Biology - June 29, 2016 Category: Biology Authors: Matteo Mori Source Type: research

Retrospective Analysis of an Interdisciplinary Ventilator Care Program Intervention on Survival of Infants with Ventilator-Dependent Bronchopulmonary Dysplasia
Conclusion These findings suggest an interdisciplinary approach to the care of infants with ventilator-dependent BPD can improve survival.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - June 29, 2016 Category: Perinatology & Neonatology Authors: Gien, JasonKinsella, JohnThrasher, JodiGrenolds, AliciaAbman, Steven H.Baker, Christopher D. Tags: Original Article Source Type: research

Long‐term clinical safety and efficacy of brodalumab in the treatment of Japanese patients with moderate‐to‐severe plaque psoriasis
ConclusionBrodalumab showed a sustained clinical response and an acceptable safety profile through 52 weeks in Japanese patients with moderate‐to‐severe plaque psoriasis in this open‐label extension study. (Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - June 29, 2016 Category: Dermatology Authors: Y. Umezawa, H. Nakagawa, H. Niiro, K. Ootaki, Tags: Short Report Source Type: research

Risk factors associated with RSV hospitalisation in the first 2 years of life, among different subgroups of children in NSW: a whole-of-population-based cohort study
Discussion Promoting avoidance of smoking during pregnancy may help in lowering the disease burden, with Indigenous children likely to benefit most. (Source: BMJ Open)
Source: BMJ Open - June 29, 2016 Category: Journals (General) Authors: Homaira, N., Mallitt, K.-A., Oei, J.-L., Hilder, L., Bajuk, B., Lui, K., Rawlinson, W., Snelling, T., Jaffe, A. Tags: Open access, Infectious diseases, Paediatrics Research Source Type: research

'Cathy became my confidante'.
Abstract I was wary of a respiratory nurse becoming involved in my care. I had a good relationship with the respiratory consultants and, although I was unwell and things were difficult, I did not see what another nurse could add. I could not have been more wrong. PMID: 27353939 [PubMed - in process] (Source: Nursing Standard)
Source: Nursing Standard - June 29, 2016 Category: Nursing Authors: Nash E Tags: Nurs Stand Source Type: research

Mitochondrial Function in an In Vitro Model of Skeletal Muscle of Patients With Protracted Critical Illness and Intensive Care Unit-Acquired Weakness.
CONCLUSION: In an in vitro model of skeletal muscle of patients with protracted critical illness, we have shown signs of adaptation to increased FAO. Even in the presence of glucose and insulin, elevation of FFAs in the extracellular environment increased maximal capacity of the respiratory chain. PMID: 27358332 [PubMed - as supplied by publisher] (Source: JPEN Journal Of Parenteral And Enteral Nutrition)
Source: JPEN Journal Of Parenteral And Enteral Nutrition - June 29, 2016 Category: Nutrition Authors: Jiroutková K, Krajčová A, Žiak J, Fric M, Gojda J, Džupa V, Kalous M, Tůmová J, Trnka J, Duška F Tags: JPEN J Parenter Enteral Nutr Source Type: research

Primary pulmonary T-cell lymphoma mimicking pneumonia: A case report and literature review.
Authors: Yang L, Feng W, Chen C, Zhang X, Zhu Y, Lei W, Huang JA Abstract Primary pulmonary T-cell lymphoma is an extremely rare neoplasm. The present study describes the case of an elderly male patient who was admitted to hospital with initial symptoms including a fever, coughing and dyspnea. A chest computed tomography scan detected pneumonia-like features, including multiple variable nodules, ground-glass opacities, patchy infiltration and subpleural consolidation, which progressed rapidly. No mediastinal or hilar adenopathy was noted. The patient was initially diagnosed with severe pneumonia; however, the patie...
Source: Experimental and Therapeutic Medicine - June 28, 2016 Category: Journals (General) Tags: Exp Ther Med Source Type: research

Thrombotic thrombocytopenic purpura (TPP) successfully rescued by plasma exchange in the ICU: A report of two cases.
Authors: Zou X, Wu T, Zhang X, Qu A, Tian S Abstract Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disorder, which is characterized by thrombus formation in small blood vessels. The present study retrospectively analyzed the clinical data from two patients with severe TTP, who were treated successfully in the intensive care unit (ICU) at the Liaocheng People's Hospital in 2013. Comprehensive therapies were administered to the patients, including plasma exchange (PE), mechanical ventilation (case 1 only), steroid therapy, blood transfusion and anti-inflammatory treatment (case 2 only). The tw...
Source: Experimental and Therapeutic Medicine - June 28, 2016 Category: Journals (General) Tags: Exp Ther Med Source Type: research

The Interaction Between Child Respiratory Sinus Arrhythmia and Early Sensitive Parenting in the Prediction of Children's Executive Functions
This study investigated the interaction between children's parasympathetic functioning and maternal sensitive parenting behaviors during infancy and toddlerhood in the prediction of children's executive functions (EF) at the age of 5 years. Participants included 137 children and their mothers who were followed from the age of 3 months to 5 years. Children's cardiac activity was recorded at rest at multiple times from ages 3 to 36 months, and estimates of respiratory sinus arrhythmia (RSA; a measure of parasympathetic functioning) were calculated. Sensitive parenting was assessed during a mother–child play task at age...
Source: Infancy - June 28, 2016 Category: Child Development Authors: Noa Gueron‐Sela, Nicholas J. Wagner, Cathi B. Propper, W. Roger Mills‐Koonce, Ginger A. Moore, Martha J. Cox Tags: Research Article Source Type: research

Behavioral and cardiopulmonary effects of dexmedetomidine–midazolam and dexmedetomidine–midazolam–butorphanol in the silver fox (Vulpes vulpes)
Conclusions and clinical relevanceIT and RT were not different between the groups. Both protocols provided immobilization for 30–40 minutes with excellent muscle relaxation and analgesia adequate for clinical examinations and some simple surgical procedures. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - June 28, 2016 Category: Veterinary Research Authors: Hong‐Xiu Diao, Shuai Zhang, Xue‐Yuan Hu, Wei Guan, Li Luan, Hai‐Yu Liu, Hong‐Gang Fan Tags: Research Paper Source Type: research

ICU-based therapy fails to shorten hospital stay
Standardized rehabilitation therapy did not reduce hospital length of stay in patients with acute respiratory failure, based on data from a randomized trial of 300 adults published online in JAMA.... (Source: Hospitalist News)
Source: Hospitalist News - June 28, 2016 Category: Hospital Management Source Type: research

Enrolment in an Asthma Management Program during Pregnancy and Adherence with Inhaled Corticosteroids: The ‘Management of Asthma during Pregnancy' Program
Conclusion: Enrolment in an asthma management program during pregnancy seems to improve adherence with controller medication, but self-reported adherence is not a valid measure for actual adherence in patients with asthma.Respiration (Source: Respiration)
Source: Respiration - June 28, 2016 Category: Respiratory Medicine Source Type: research

Can the New Global Lung Initiative Equations Better Stratify the Risk of Death in Elderly People with Chronic Obstructive Pulmonary Disease
Conclusion: The GLI equations for predicting FEV1 provide similar estimates compared to an equation developed in a healthy subset of the population in which they are applied, and higher values compared to the ERS equation, especially in women. However, the use of the GLI equation does not improve the stratification of the risk of mortality in elderly people compared to ERS or NHANES equations.Respiration (Source: Respiration)
Source: Respiration - June 28, 2016 Category: Respiratory Medicine Source Type: research

Spontaneous Pneumomediastinum as a Potential Predictor of Mortality in Patients with Idiopathic Pulmonary Fibrosis
Conclusions: Spontaneous PM is a rare but serious complication in patients with IPF and may be considered as a potential predictor of mortality.Respiration (Source: Respiration)
Source: Respiration - June 28, 2016 Category: Respiratory Medicine Source Type: research

Anticholinergic medicines in an older primary care population: a cross‐sectional analysis of medicines’ levels of anticholinergic activity and clinical indications
Summary What is known and objectivesAdverse clinical outcomes have been associated with cumulative anticholinergic burden (to which low‐potency as well as high‐potency anticholinergic medicines contribute). The clinical indications for which anticholinergic medicines are prescribed (and thus the ‘phenotype’ of patients with anticholinergic burden) have not been established. We sought to establish the overall prevalence of prescribing of anticholinergic medicines, the prevalence of prescribing of low‐, medium‐ and high‐potency anticholinergic medicines, and the clinical indications for which the medicines were...
Source: Journal of Clinical Pharmacy and Therapeutics - June 28, 2016 Category: Drugs & Pharmacology Authors: P. J. Magin, S. Morgan, A. Tapley, C. McCowan, L. Parkinson, K. M. Henderson, C. Muth, M. S. Hammer, D. Pond, K. E. Mate, N. A. Spike, L. A. McArthur, M. L. Driel Tags: Original Article Source Type: research

ICU Rehabilitation and Length of Stay for Acute Respiratory Failure Patients
This randomized clinical trial compares the effects of physical rehabilitation vs usual care on length of stay of ICU patients with acute respiratory failure. (Source: JAMA)
Source: JAMA - June 28, 2016 Category: Journals (General) Source Type: research

The Centennial of the Stethoscope
One of the great steps in the advancement of internal medicine was the discovery of auscultation. One hundred years ago, in 1816, Laennec, a favorite pupil of Corvisart, was appointed to the position of chief physician at the Necker Hospital in Paris. He was then 35 years of age. There he began his early studies on mediate auscultation with an instrument to which he gave the name of stethoscope, derived from the words στηθος, the breast, and σκοπεω, examine. Hippocrates, says Sir Benjamin Ward Richardson, himself might have invented it, and would at once have understood it. Then followed the naming of sounds na...
Source: JAMA - June 28, 2016 Category: Journals (General) Source Type: research

Pneumococcal meningitis is promoted by single cocci expressing pilus adhesin RrgA
Streptococcuspneumoniae (pneumococcus) is the primary cause of bacterial meningitis. Pneumococcal bacteria penetrates the blood-brain barrier (BBB), but the bacterial factors that enable this process are not known. Here, we determined that expression of pneumococcal pilus-1, which includes the pilus adhesin RrgA, promotes bacterial penetration through the BBB in a mouse model. S. pneumoniae that colonized the respiratory epithelium and grew in the bloodstream were chains of variable lengths; however, the pneumococci that entered the brain were division-competent, spherical, single cocci that expressed adhesive RrgA–conta...
Source: Journal of Clinical Investigation - June 28, 2016 Category: Biomedical Science Authors: Federico Iovino, Disa L. Hammarlöf, Genevieve Garriss, Sarah Brovall, Priyanka Nannapaneni, Birgitta Henriques-Normark Source Type: research

Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus
Publication date: 20 August 2016 Source:International Journal of Pharmaceutics, Volume 510, Issue 1 Author(s): Harish Bokkasam, Matthias Ernst, Marco Guenther, Christian Wagner, Ulrich F. Schaefer, Claus-Michael Lehr Aim of this study was to investigate the similarities and differences at macro- and microscale in the viscoelastic properties of mucus that covers the epithelia of the intestinal and respiratory tract. Natural mucus was collected from pulmonary and intestinal regions of healthy pigs. Macro-rheological investigations were carried out through conventional plate–plate rheometry. Microrheology was invest...
Source: International Journal of Pharmaceutics - June 28, 2016 Category: Drugs & Pharmacology Source Type: research

Disseminated tuberculosis with prostatic abscesses in an immunocompromised patient—A case report and review of literature
We describe a case of disseminated Mycobacterium tuberculosis (mTB) with prostatic abscess in a newly diagnosed HIV patient in the United States. The patient is a 34 year-old male who presented with respiratory symptoms and was diagnosed with HIV/AIDS complicated by disseminated mTB infection of the lungs, liver, and prostate. His prostate showed abscess formation on imaging that required drainage however he did not present with any genitourinary complaints. Our literature review revealed that prostatic involvement in mTB in the form of granulomatous prostatitis is uncommon; however, abscess formation is extremely rare and...
Source: IDCases - June 28, 2016 Category: Infectious Diseases Source Type: research

Patient safety events in hospital care of individuals with epilepsy
Summary Objectives(1) To describe patient adverse events (PAEs) experienced by hospitalized individuals with epilepsy and examine the association of an epilepsy diagnosis on risk of specific PAEs; (2) to examine the impact of a PAE on (a) length of stay (LOS), (b) inpatient death, and (c) use of institutional post‐acute care. MethodsWe applied the Agency for Healthcare Research and Quality (AHRQ) Patient Safety Indicator (PSI) software to the National Inpatient Sample database to identify potential medical and postoperative PAEs among >72 million hospitalizations of adults in the United States from 2000 to 2010. Logis...
Source: Epilepsia - June 28, 2016 Category: Neurology Authors: Adys Mendizabal, Dylan P. Thibault, Allison W. Willis Tags: Full ‐Length Original Research Source Type: research

IJERPH, Vol. 13, Pages 643: Household Air Pollution Exposure and Influence of Lifestyle on Respiratory Health and Lung Function in Belizean Adults and Children: A Field Study
In conclusion, adults exposed to HAP experienced greater respiratory and non-respiratory symptoms, which may be attenuated by lifestyle modifications. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - June 28, 2016 Category: Environmental Health Authors: Stephanie KurtiAllison KurtiSam EmersonRichard RosenkranzJoshua SmithCraig HarmsSara Rosenkranz Tags: Article Source Type: research

Distribution and dynamics of quinones in the lipid bilayer mimicking the inner membrane of mitochondria
Publication date: September 2016 Source:Biochimica et Biophysica Acta (BBA) - Biomembranes, Volume 1858, Issue 9 Author(s): Petri Kaurola, Vivek Sharma, Amanda Vonk, Ilpo Vattulainen, Tomasz Róg Quinone and its analogues (Q) constitute an important class of compounds that perform key electron transfer reactions in oxidative- and photo-phosphorylation. In the inner membrane of mitochondria, ubiquinone molecules undergo continuous redox transitions enabling electron transfer between the respiratory complexes. In such a dynamic system undergoing continuous turnover for ATP synthesis, an uninterrupted supply of substra...
Source: Biochimica et Biophysica Acta (BBA) Biomembranes - June 28, 2016 Category: Biochemistry Source Type: research

Measuring the short‐term substrate utilization response to high‐carbohydrate and high‐fat meals in the whole‐body indirect calorimeter
Abstract The paper demonstrates that minute‐to‐minute metabolic response to meals with different macronutrient content can be measured and discerned in the whole‐body indirect calorimeter. The ability to discriminate between high‐carbohydrate and high‐fat meals is achieved by applying a modified regularization technique with additional constraints imposed on oxygen consumption rate. These additional constraints reduce the differences in accuracy between the oxygen and carbon dioxide analyzers. The modified technique was applied to 63 calorimeter sessions that were each 24 h long. The data were collected from 16 ...
Source: Physiological Reports - June 28, 2016 Category: Physiology Authors: Andrei Gribok, Jayme L. Leger, Michelle Stevens, Reed Hoyt, Mark Buller, William Rumpler Tags: Original Research Source Type: research