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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 6.

Redox imaging of inflammation in asthma.
PMID: 24628314 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 15, 2014 Category: Respiratory Medicine Authors: Ratanamaneechat S, Neumann DR, Difilippo FP, Comhair SA, Asosingh K, Ghosh S, Grandon D, Khan A, Aronica MA, Erzurum SC Tags: Am J Respir Crit Care Med Source Type: research

Consequences of a thoracoabdominal aortic graft infection.
PMID: 24628313 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 15, 2014 Category: Respiratory Medicine Authors: Reed AJ, Horak J Tags: Am J Respir Crit Care Med Source Type: research

An official american thoracic society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease.
Conclusions: Evidence-based recommendations for the management of patients with SCD with increased mortality risk are provided, but will require frequent reassessment and updating. PMID: 24628312 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 15, 2014 Category: Respiratory Medicine Authors: Klings ES, Machado RF, Barst RJ, Morris CR, Mubarak KK, Gordeuk VR, Kato GJ, Ataga KI, Gibbs JS, Castro O, Rosenzweig EB, Sood N, Hsu L, Wilson KC, Telen MJ, Decastro LM, Krishnamurti L, Steinberg MH, Badesch DB, Gladwin MT, ATS Ad Hoc Committee on Pulmon Tags: Am J Respir Crit Care Med Source Type: research

The lymphatic system in malignant pleural effusion. Drain or immune switch?
PMID: 24628311 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 15, 2014 Category: Respiratory Medicine Authors: Marazioti A, Blackwell TS, Stathopoulos GT Tags: Am J Respir Crit Care Med Source Type: research

β2-Agonists and Acute Respiratory Distress Syndrome.
PMID: 24628310 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 15, 2014 Category: Respiratory Medicine Authors: Budinger GR, Mutlu GM Tags: Am J Respir Crit Care Med Source Type: research

Of delirium and sedation.
PMID: 24628309 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 15, 2014 Category: Respiratory Medicine Authors: Takala J Tags: Am J Respir Crit Care Med Source Type: research

Magnetic resonance imaging of inflammation in subjects with allergic asthma.
PMID: 24628308 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 15, 2014 Category: Respiratory Medicine Authors: Newell JD Tags: Am J Respir Crit Care Med Source Type: research

Severe asthma: pragmatic clinical lumping and time for investigational splitting.
PMID: 24628307 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 15, 2014 Category: Respiratory Medicine Authors: Israel E, Papi A Tags: Am J Respir Crit Care Med Source Type: research

The vitamin E isoforms ¿-tocopherol and ¿-tocopherol have opposite associations with spirometric parameters: the CARDIA study
Conclusion: Increasing serum concentrations of γ-tocopherol were associated with lower FEV1 or FVC, whereas increasing serum concentrations of α-tocopherol was associated with higher FEV1 or FVC. Based on the prevalence of serum γ-tocopherol >10 μM in adults in CARDIA and the adult U.S. population in the 2011 census, we expect that the lower FEV1 and FVC at these concentrations of serum γ-tocopherol occur in up to 4.5 million adults in the population. (Source: Respiratory Research)
Source: Respiratory Research - March 15, 2014 Category: Respiratory Medicine Authors: Michelle MarcheseRajesh KumarLaura ColangeloPedro AvilaDavid JacobsMyron GrossAkshay SoodKiang LiuJoan Cook-Mills Source Type: research

A new nanoPCR molecular assay for detection of porcine bocavirus.
Abstract Nanoparticle-assisted polymerase chain reaction (nanoPCR) is a novel method for the rapid amplification of DNA and has been used for the detection of virus. For detection of porcine bocavirus (PBoV), a sensitive and specific nanoPCR assay was developed with a pair of primers that were designed based on NS1 gene sequences available in GenBank. Under the optimized conditions of the PBoV nanoPCR assay, the nanoPCR assay was 100-fold more sensitive than a conventional PCR assay. The lower detection limit of the nanoPCR assay was about 6.70×10(1) copies. The nanoPCR assay amplified the specific 482-bp fragment...
Source: Journal of Virological Methods - March 15, 2014 Category: Virology Authors: Wang X, Bai A, Zhang J, Kong M, Cui Y, Ma X, Ai X, Tang Q, Cui S Tags: J Virol Methods Source Type: research

The Impact of Porcine Reproductive and Respiratory Syndrome Virus genetic heterogeneity on molecular assay performances.
Abstract The remarkable economic losses due to Porcine Reproductive and Respiratory Syndrome (PRRS) have stated the control and eradication of this disease one of the main issue of swine modern farming. The limited cross-protection of vaccine-induced immunity compelled the adoption of strict biosecurity measures that must be associated with the prompt diagnosis of infection. In our study four RT-PCR methods, a RT-PCR, a SYBR Green I and two hydrolysis probes, were compared to evaluate their respective benefits and disadvantages. One hundred and seventy samples originating from 50 farms located in northern Italy wer...
Source: Journal of Virological Methods - March 15, 2014 Category: Virology Authors: Drigo M, Franzo G, Gigli A, Martini M, Mondin A, Gracieux P, Ceglie L Tags: J Virol Methods Source Type: research

CrossTalk opposing view: The pre-Botzinger complex is not essential for respiratory depression following systemic administration of opioid analgesics.
PMID: 24634012 [PubMed - in process] (Source: The Journal of Physiology)
Source: The Journal of Physiology - March 15, 2014 Category: Physiology Authors: Lalley PM, Pilowsky PM, Forster HV, Zuperku EJ Tags: J Physiol Source Type: research

CrossTalk proposal: The preBotzinger complex is essential for the respiratory depression following systemic administration of opioid analgesics.
PMID: 24634011 [PubMed - in process] (Source: The Journal of Physiology)
Source: The Journal of Physiology - March 15, 2014 Category: Physiology Authors: Montandon G, Horner R Tags: J Physiol Source Type: research

Long-Term Outcomes of Patients With Absent Pulmonary Valve Syndrome: 38 Years of Experience.
CONCLUSIONS: Long-term survival for absent pulmonary valve syndrome has improved during the last decade. Preoperative ventilation predicted longer postoperative ventilation and mortality. PMID: 24636707 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - March 15, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Yong MS, Yim D, Brizard CP, Robertson T, Bullock A, d'Udekem Y, Konstantinov IE Tags: Ann Thorac Surg Source Type: research

Bronchiolitis obliterans with allogeneic hematopoietic cell transplantation: a 10-year experience of the Okayama BMT Group.
Abstract Bronchiolitis obliterans (BO) is a devastating complication of allogeneic hematopoietic stem cell transplantation (HSCT). We retrospectively studied 465 patients who underwent HSCT in the Okayama BMT Group between 2000 and 2009, and describe the detailed clinical features of 13 patients with BO. The 5-year cumulative incidence of BO was 3.43 %. The median time from transplantation to onset of BO was 15 months. In seven of the 13 patients, the primary symptom was only cough, indicating that cough was an important initial symptom for early diagnosis. The median duration from the onset of BO to the requirem...
Source: International Journal of Hematology - March 15, 2014 Category: Hematology Authors: Fujii N, Nakase K, Asakura S, Matsuo K, Nawa Y, Sunami K, Nishimori H, Matsuoka KI, Kondo E, Maeda Y, Shinagawa K, Hara M, Tanimoto M Tags: Int J Hematol Source Type: research

Cystatin C: A potential biomarker for pulmonary arterial hypertension
ConclusionsIn a small cohort, CysC accurately correlates with RV pressure, function and morphology. CysC may represent a novel PAH biomarker. (Source: Respirology)
Source: Respirology - March 14, 2014 Category: Respiratory Medicine Authors: Brett E. Fenster, Luis Lasalvia, Joyce D. Schroeder, Jamey Smyser, Lori J. Silveira, J. Kern Buckner, Kevin K. Brown Tags: Original Article Source Type: research

[Treatment and rehabilitation of dysphagia following cerebrovascular disease].
CONCLUSIONS. The studies examined in this research claim that the treatment of dysphagia following a stroke can improve the function of deglutition (coordination, speed, volume), quality of life and people's social relationships. Further work needs to be carried out to establish or define what kind of therapies, techniques, exercises or manoeuvres are the most effective in dysphagia. Generally agreed treatment or rehabilitation protocols also need to be drawn up within units that address stroke in an integrated manner. PMID: 24610693 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - March 14, 2014 Category: Neurology Authors: Lopez-Liria R, Fernandez-Alonso M, Vega-Ramirez FA, Salido-Campos MA, Padilla-Gongora D Tags: Rev Neurol Source Type: research

[Comment] Respiratory medicine and critical care: a call for papers
At the 2013 European Respiratory Society (ERS) Annual Congress, the European Lung White Book was launched which showed that in the WHO-defined European region one in ten deaths are caused by either chronic obstructive pulmonary disease (COPD), lung cancer, tuberculosis, or a lower respiratory tract infection such as pneumonia. The landscape was much the same in the first version of the white book published 10 years ago, and, even more alarmingly, WHO reports that one in six deaths worldwide result from these four lung diseases. (Source: LANCET)
Source: LANCET - March 14, 2014 Category: Journals (General) Authors: Jane Godsland, Emma Grainger, Sabine Kleinert Tags: Comment Source Type: research

Eustachian tube opening measured by sonotubometry is poorer in adults with a history of past middle ear disease
Conclusions: Quantifiable measures of the sound signal “shape” recorded by sonotubometry during swallowing were significantly different between the 2 groups of subjects. This is interpretable as evidencing a more efficient Eustachian tube opening-function in adults with healthy middle ears who do not have a previous history of otitis media when compared to similar adults with a history of prior otitis media. Inefficient Eustachian tube function as children may not be completely resolved by adulthood increasing adult otitis media risk when Eustachian tube function is down-graded by extant upper respiratory diseases that...
Source: International Journal of Pediatric Otorhinolaryngology - March 14, 2014 Category: ENT & OMF Authors: Miriam S. Teixeira, Juliane Banks, J. Douglas Swarts, Cuneyt M. Alper, William J. Doyle Tags: Research papers Source Type: research

Upcoming events of interest
(Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - March 14, 2014 Category: Respiratory Medicine Tags: Upcoming Events Source Type: research

The Saudi guidelines for chronic obstructive pulmonary disease: A fresh "Real-World" approach to COPD
Nicola A HananiaAnnals of Thoracic Medicine 2014 9(2):53-54 (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Nicola A Hanania Source Type: research

The Saudi guidelines for the diagnosis and management of COPD
Javed H Khan, Hani M. S. Lababidi, Mohamed S Al-Moamary, Mohammed O Zeitouni, Hamdan H AL-Jahdali, Omar S Al-Amoudi, Siraj O Wali, Majdy M Idrees, Abdullah A Al-Shimemri, Mohammed O Al Ghobain, Hassan S Alorainy, Mohamed S Al-HajjajAnnals of Thoracic Medicine 2014 9(2):55-76The Saudi Thoracic Society (STS) launched the Saudi Initiative for Chronic Airway Diseases (SICAD) to develop a guideline for the diagnosis and management of chronic obstructive pulmonary disease (COPD). This guideline is primarily aimed for internists and general practitioners. Though there is scanty epidemiological data related to COPD, the SICAD pane...
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Javed H KhanHani M. S. LababidiMohamed S Al-MoamaryMohammed O ZeitouniHamdan H AL-JahdaliOmar S Al-AmoudiSiraj O WaliMajdy M IdreesAbdullah A Al-ShimemriMohammed O Al GhobainHassan S AlorainyMohamed S Al-Hajjaj Source Type: research

Magnesium for acute exacerbation of chronic obstructive pulmonary disease: A systematic review of randomised trials
Mitrakrishnan Chrishan Shivanthan, Senaka RajapakseAnnals of Thoracic Medicine 2014 9(2):77-80The efficacy of magnesium sulphate in chronic obstructive pulmonary disease (COPD) was assessed by conducting a systematic review of published randomized clinical trials through extensive searches in MEDLINE and SCOPUS with no date limits, as well as manual review of journals. Outcome measures varied depending on route(s) of administration of magnesium sulphate and medications co-administered. Risk of bias was evaluated and quality of evidence was graded. Four (4) randomized trials were included. All trials had a moderate risk of ...
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Mitrakrishnan Chrishan ShivanthanSenaka Rajapakse Source Type: research

IL-4 receptor alpha single-nucleotide polymorphisms rs1805010 and rs1801275 are associated with increased risk of asthma in a Saudi Arabian population
Conclusions: The risk alleles, G, of IL-4Rα rs1805010 and rs1801275 SNPs and corresponding A/G-G/G genotypes were significantly associated with asthma predisposition in asthmatics from Saudi Arabia. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Saleh Al-MuhsenAlejandro Vazquez-TelloAshraf AlzaabiMohamed S Al-HajjajHamdan H Al-JahdaliRabih Halwani Source Type: research

Frequency and predictors of obesity hypoventilation in hospitalized patients at a tertiary health care institution
Conclusions: OHS is a common cause of chronic alveolar hypoventilation. A careful examination PaCO 2 /BMI ratio may prevent misdiagnoses among hypercapnic patients. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Yilmaz BülbülSibel AyikTevfik OzluAsim Orem Source Type: research

Obstructive sleep apnea is associated with higher healthcare utilization in elderly patients
Conclusion: Patients with OSA had a higher incidence of healthcare utilization compared to patients without OSA. New OSA patients had a higher rate of healthcare utilization in the year of diagnosis compared to chronic patients and patients without OSA. Early OSA recognition may reduce healthcare utilization in these patients. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Karla DiazPaola FaverioAngela HospenthalMarcos I RestrepoMegan E AmuanMary Jo V Pugh Source Type: research

B-lines: Transthoracic chest ultrasound signs useful in assessment of interstitial lung diseases
Conclusion: B-lines that are lung Ultrasound signs seem to be useful in the assessment of ILD. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Ali A HasanHoda A Makhlouf Source Type: research

Drug-resistant ventilator associated pneumonia in a tertiary care hospital in Saudi Arabia
Conclusion: Acinetobacter in the current study was an increasingly resistant VAP-associated pathogen more than seen in many parts of the world. The current finding may impact local choice of initial empiric antibiotics. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Hanan H BalkhyAiman El-SaedRana MaghrabyHasan M Al-DorziRaymond KhanAsgar H RishuYaseen M Arabi Source Type: research

Positive end-expiratory pressure attenuates positional effect after thoracotomy
Conclusion: There were significant changes with regards to pulmonary gas exchange, hemodynamics and C rs after thoracotomy. The best position was non-operated lung lowermost Applying PEEP attenuates the positional effects. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Chou-Chin LanHsian-He HsuChin-Pyng WuShih-Chun LeeChung-Kan PengHung Chang Source Type: research

Endobronchial cryotherapy facilitates end-stage treatment options in patients with bronchial stenosis: A case series
We report our experience of the first time use of endobronchial cryotherapy in Ireland with reference to a case series, including an example of its use in the management of benign disease, in order to support patients with borderline lung function and enable definitive palliative treatment. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Gerard J FitzmauriceKaren C RedmondDavid A FitzpatrickWaldemar Bartosik Source Type: research

Successful management of bilateral refractory chylothorax after double lung transplantation for lymphangioleiomyomatosis
We report a case of LAM that underwent double LT and complicated by refractory bilateral chylothorax which was managed successfully by povidone-iodine pleurodesis and the addition of sirolimus to the post-transplantation immunosuppressive therapy. The patient has no recurrence with 24 months follow-up. (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Mohammed HusseinYasser M AljehaniImran NizamiWaleed Saleh Source Type: research

Endobronchial ultrasound as a confirmatory tool for the diagnosis of pulmonary embolism
Kassem Harris, Michel ChalhoubAnnals of Thoracic Medicine 2014 9(2):127-128 (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Kassem HarrisMichel Chalhoub Source Type: research

Determining an optimal technique for atrial septal defect closure: percutaneous closure as a therapeutic modality of choice
Emre Yalcinkaya, Murat Celik, Baris BuganAnnals of Thoracic Medicine 2014 9(2):128-128 (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Emre YalcinkayaMurat CelikBaris Bugan Source Type: research

Author reply to the editor
Hua CaoAnnals of Thoracic Medicine 2014 9(2):129-129 (Source: Annals of Thoracic Medicine)
Source: Annals of Thoracic Medicine - March 14, 2014 Category: Respiratory Medicine Authors: Hua Cao Source Type: research

Health-related quality of life in patients with chronic obstructive pulmonary disease in North India
Conclusion: HRQL of COPD patients was significantly impaired across stages. Marked impairment of HRQL was found even in patients with mild disease. (Source: Journal of Postgraduate Medicine)
Source: Journal of Postgraduate Medicine - March 14, 2014 Category: Internal Medicine Authors: H NegiM SarkarAD RavalK PandeyP Das Source Type: research

Notch1 Activation Alters Mitochondrial Proteome [Genomics and Proteomics]
The Notch signaling pathway, a known regulator of cell fate decisions, proliferation, and apoptosis, has recently been implicated in the regulation of glycolysis, which affects tumor progression. However, the impact of Notch on other metabolic pathways remains to be elucidated. To gain more insights into the Notch signaling and its role in regulation of metabolism, we studied the mitochondrial proteome in Notch1-activated K562 cells using a comparative proteomics approach. The proteomic study led to the identification of 10 unique proteins that were altered due to Notch1 activation. Eight of these proteins belonged to mito...
Source: Journal of Biological Chemistry - March 14, 2014 Category: Chemistry Authors: Basak, N. P., Roy, A., Banerjee, S. Tags: Metabolism Source Type: research

Role of ER Stress in Respiratory Syncytial Virus Infection [Cell Biology]
In this study, we investigate the role of the ER stress response in RSV infection using an in vitro A549 cell culture model. We found that RSV infection induces a non-canonical ER stress response with preferential activation of the inositol-requiring enzyme 1 (IRE1) and activated transcription factor 6 (ATF6) pathways with no concomitant significant activation of the protein kinase R-like ER kinase (PERK) pathway. Furthermore, we discovered that IRE1 has an inhibitory effect on RSV replication. Our data characterize, for the first time, the nature of the ER stress response in the setting of RSV infection and identify the I...
Source: Journal of Biological Chemistry - March 14, 2014 Category: Chemistry Authors: Hassan, I., Gaines, K. S., Hottel, W. J., Wishy, R. M., Miller, S. E., Powers, L. S., Rutkowski, D. T., Monick, M. M. Tags: Cell Biology Source Type: research

Early ambulatory palliative care visits focus on psychosocial elements such as building rapport and coping, as well as managing symptoms and enhancing illness understanding
This study has had significant impact, but many professionals have asked for more details about palliative care interventions. Findings from the present study will help define what palliative care specifically provides. Context Professional organisations in the fields of oncology, such as the American Society of Clinical Oncology2 and palliative care, including the American Academy of Hospice and Palliative Medicine, have articulated the need for palliative care to be integrated into disease-focused care. There has been a wide international interest in this area as well. Achieving this aim will require a greater understand...
Source: Evidence-Based Nursing - March 14, 2014 Category: Nursing Authors: Ferrell, B. Tags: End of life decisions (geriatric medicine), Adult nursing, Stroke, Lung cancer (oncology), End of life decisions (palliative care), Hospice, Lung cancer (respiratory medicine), End of life decisions (ethics), Resuscitation, Information management Source Type: research

Prescriber preference may influence prolonged antibiotic usage more than patient characteristics in long-term care facilities
Commentary on: Daneman N, Gruneir A, Bronskill SE, et al.. Prolonged antibiotic treatment in long-term care: role of the prescriber. JAMA Intern Med 2013;173:673–82. Implications for practice and research Longer antimicrobial prescription durations are often driven by prescriber preference. Antimicrobial stewardship strategies should focus on prescription durations and target the determinants of prescriber behaviours in order to improve long-term care facilities (LTCF) antimicrobial prescribing. Context Recent point prevalence studies have revealed that antimicrobial use in LTCF is highly variable, with 1.4% of resi...
Source: Evidence-Based Nursing - March 14, 2014 Category: Nursing Authors: Fleming, A., Byrne, S. Tags: Drugs: infectious diseases, Pneumonia (infectious disease), TB and other respiratory infections, Urinary tract infections, Pneumonia (respiratory medicine), Urinary tract infections Care of the older person Source Type: research

Exenatide improves hepatic steatosis by enhancing lipid use in adipose tissue in nondiabetic rats.
CONCLUSION: In addition to reducing appetite, enhanced lipid use by exenatide in adipose tissue may reduce hepatic lipid content in NAFLD, most likely by decreasing lipid influx into the liver. PMID: 24627601 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 14, 2014 Category: Gastroenterology Authors: Tanaka K, Masaki Y, Tanaka M, Miyazaki M, Enjoji M, Nakamuta M, Kato M, Nomura M, Inoguchi T, Kotoh K, Takayanagi R Tags: World J Gastroenterol Source Type: research