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Respiratory Medicine

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 7.

Workaholism: are physicians at risk?
Conclusions WA especially affects professors, who have the highest status amongst doctors in the hospital hierarchy. This study highlights the importance of constraints and workload, which are consistent with individual vulnerability factors. These factors may help identify ways of preventing and managing this type of addiction, through improvement of working conditions and organizational structures. (Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Rezvani, A., Bouju, G., Keriven-Dessomme, B., Moret, L., Grall-Bronnec, M. Tags: Mental health Original Paper Source Type: research

Self-reported and employer-recorded sickness absence in doctors
Conclusions Doctors’ sickness absence was significantly under-recorded in this study population. (Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Murphy, I. J. Tags: Healthcare workers Original Paper Source Type: research

Cancer incidence and mortality in serving whole-time Scottish firefighters 1984-2005
Conclusions These results are generally consistent with other studies of firefighters. The most common tumours were generally those associated with young and middle-aged men. (Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Ide, C. W. Tags: Occupational cancers, Renal and urological disorders, Fire and rescue service Original Paper Source Type: research

Duty-related risk of sudden cardiac death among young US firefighters
Conclusions The performance of strenuous emergency duties is strongly associated with an increased risk of SCD among young firefighters, particularly among those with a history of cardiovascular disease. (Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Farioli, A., Yang, J., Teehan, D., Baur, D. M., Smith, D. L., Kales, S. N. Tags: Fire and rescue service Original Paper Source Type: research

Effect of unemployment on cardiovascular risk factors and mental health
Conclusions The patterns of major cardiovascular risk factors differed between unemployed and employed individuals in Poland. Our observations suggest employment status is a predictor of specific disease risk profiles; consequently, specific preventive measures are needed in unemployed individuals. (Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Zagozdzon, P., Parszuto, J., Wrotkowska, M., Dydjow-Bendek, D. Tags: Mental health Original Paper Source Type: research

Health and safety legislation
(Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Gibson, M. Tags: Filler Source Type: research

Pneumoconiosis in dental technicians: HRCT and pulmonary function findings
Conclusions Pneumoconiosis identified by HRCT was present in almost half of DPTs surveyed. Appropriate education and workplace protection should be given to DPTs in order to prevent exposure to hazardous materials in dental prosthetics laboratories. (Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Kahraman, H., Koksal, N., Cinkara, M., Ozkan, F., Sucakli, M. H., Ekerbicer, H. Tags: Respiratory Disorders Original Paper Source Type: research

The Ontario Workplace Health Champions Program
(Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Holness, D. L., Liss, G. Tags: Filler Source Type: research

Epilepsy, diabetes mellitus and accidental injury at work
Conclusions No evidence was found that diabetes or epilepsy are important contributors to workplace injury in Britain. (Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Palmer, K. T., D'Angelo, S., Harris, E. C., Linaker, C., Coggon, D. Tags: Neurological disorders, Endocrine disorders Original Paper Source Type: research

The raincoat sign
(Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Hobson, J. Tags: Filler Source Type: research

Neurodegenerative disease and magnetic field exposure in UK electricity supply workers
Conclusions There is no convincing evidence that UK electricity generation and transmission workers have suffered elevated risks from neurodegenerative diseases as a consequence of exposure to magnetic fields. (Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Sorahan, T., Mohammed, N. Tags: Neurological disorders Original Paper Source Type: research

Fitness, obesity and risk of heat illness among army trainees
Conclusions This study demonstrated that fitness and body fat are independently associated with incident EHI, and the effect of both was substantially higher. Those with low fitness levels and/or obesity should be evaluated further before engaging in intense physical activity, especially in warmer months. (Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Bedno, S. A., Urban, N., Boivin, M. R., Cowan, D. N. Tags: Heat Original Paper Source Type: research

Fifty years ago: 'Occupational health: An employer's view'
(Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Tags: Filler Source Type: research

Chronic paronychia in a hairdresser
We report an unusual case of chronic paronychia in a female hairdresser which occurred as a consequence of a hair shaft penetrating beneath the nail fold. Personal hygiene with thorough removal of any hairs that have penetrated the epidermis and wearing clean gloves can prevent the condition. We suggest that clinicians should be aware of the types of occupation and mechanisms involved in patients developing chronic paronychia. (Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Allouni, A., Yousif, A., Akhtar, S. Tags: Biological/occupational infections Case Report Source Type: research

Sensitization to pets in pet shop workers
(Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Liccardi, G., Steinhilber, G., Meriggi, A., Sapio, C., D'Amato, G. Tags: Respiratory Disorders, Women at work, Dusts and particles Letter to the Editor Source Type: research

Reply
(Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Yilmaz, I., Oner Erkekol, F., Secil, D., Misirligil, Z., Mungan, D. Tags: Respiratory Disorders Letter to the Editor Source Type: research

Bronchiolitis obliterans
(Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Guidotti, T. L. Tags: Respiratory Disorders, Gases Letter to the Editor Source Type: research

The CAGE questionnaire
(Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Williams, N. Tags: Mental health Questionnaire Review Source Type: research

The Oxford Handbook of Health Communication, Behavior Change, and Treatment Adherence
(Source: Occupational Medicine)
Source: Occupational Medicine - August 20, 2014 Category: Respiratory Medicine Authors: Williams, N. Tags: Book Review Source Type: research

Untitled
Background: Chronic obstructive pulmonary disease (COPD) is characterized by expiratory flow limitation, causing air trapping and lung hyperinflation. Hyperinflation leads to reduced exercise tolerance and poor quality of life in COPD patients. Total lung capacity (TLC) is an indicator of hyperinflation particularly in subjects with moderate-to-severe airflow obstruction. The aim of our study was to identify genetic variants associated with TLC in COPD. Methods: We performed genome-wide association studies (GWASs) in white subjects from three cohorts: the COPDGene Study; the Evaluation of COPD Longitudinally to Identify Pr...
Source: Respiratory Research - August 20, 2014 Category: Respiratory Medicine Authors: Jin LeeMerry-Lynn McDonaldMichael ChoEmily WanPeter CastaldiGary HunninghakeNathaniel MarchettiDavid LynchJames CrapoDavid LomasHarvey CoxsonPer BakkeEdwin SilvermanCraig Hersh Source Type: research

The psychometric properties of the St George¿s Respiratory Questionnaire (SGRQ) in patients with idiopathic pulmonary fibrosis: a literature review
Assessment of health-related quality of life (HRQL) is particularly important in patients with progressive and incurable diseases such as idiopathic pulmonary fibrosis (IPF). The St George?s Respiratory Questionnaire (SGRQ) has frequently been used to measure HRQL in patients with IPF, but it was developed for patients with obstructive lung diseases. The aim of this review was to examine published data on the psychometric performance of the SGRQ in patients with IPF. A comprehensive search was conducted to identify studies reporting data on the internal consistency, construct validity, test-retest reliability, and interpre...
Source: Health and Quality of Life Outcomes - August 20, 2014 Category: Global & Universal Authors: Jeffrey SwigrisDirk EsserCraig ConoscentiKevin Brown Source Type: research

Work-related exacerbation of asthma among adults treated by pulmonary specialists.
This study aimed to assess the prevalence of work-related respiratory symptoms (WRS) in asthmatic adults at pulmonary clinics. A cross-sectional study was performed. Current employed subjects were subdivided into two groups by WRS status according to questionnaire mainly based on one developed by NIOSH. Subjects' occupation and workplace exposures were evaluated by asthma specific job exposure matrix (JEM). Thirty nine of 179 current employed asthmatics had WRS. Subjects with WRS were more likely to have self-reported allergy and low molecular weight antigens' exposure (PR: 2.7). The two most frequent occupational classes ...
Source: Archives of Environmental and Occupational Health - August 20, 2014 Category: Environmental Health Authors: Sadeghniiat-Haghighi K, Aminian O, Najafi A, Salehpour S, Eslaminejad A, Derakhshan Deilami G, Nourijelyani K, Tarlo SM Tags: Arch Environ Occup Health Source Type: research

Terrimonas arctica sp. nov., isolated from Arctic tundra soil.
Abstract A novel Gram-reaction-negative, aerobic, non-motile and rod-shaped bacterium, designated R9-86(T), was isolated from tundra soil collected near Ny-Ålesund, Svalbard Archipelago, Norway (78°N). Growth occurred at 4-28℃ (optimum, 22-25℃) and at pH 6.0-9.0 (optimum, pH 7.0). Flexirubin-type pigments were absent. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain R9-86(T) belonged to the genus Terrimonas in the family Chitinophagaceae. 16S rRNA gene sequence similarities between strain R9-86T and the type strains of Terrinomas species with validly published names ranged from 93....
Source: International Journal of Systematic and Evolutionary Microbiology - August 20, 2014 Category: Microbiology Authors: Jiang F, Qiu X, Chang X, Qu Z, Ren L, Kan W, Guo Y, Fang C, Peng F Tags: Int J Syst Evol Microbiol Source Type: research

Targeting of Plasminogen Activator Inhibitor 1 Improves Fibrinolytic Therapy for Tetracycline Induced Pleural Injury in Rabbits.
Conclusions: Targeting PAI-1 did not induce bleeding and rendered otherwise ineffective doses of scuPA able to improve outcome in tetracycline-induced pleural injury. PAI-1 neutralizing mAbs improved IPFT by increasing the durability of intrapleural PA activity. These results suggest a novel, well-tolerated IPFT strategy that is tractable for clinical development. PMID: 25140386 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - August 20, 2014 Category: Molecular Biology Authors: Florova G, Azghani A, Karandashova S, Schaefer C, Koenig K, Stewart-Evans K, Declerck PJ, Idell S, Komissarov AA Tags: Am J Respir Cell Mol Biol Source Type: research

Intranasal administration of BCG induces superior protection against an aerosol infection with Mycobacterium tuberculosis in mice.
Abstract Despite widespread usage of Mycobacterium bovis BCG, the only licensed vaccine against M. tuberculosis (TB), TB remains a global epidemic. To assess whether more direct targeting of the lung mucosa by respiratory immunization would enhance potency and longevity of BCG-induced anti-tuberculosis protective immunity, the long-term impact of intranasal (i.n.) BCG vaccination was compared to conventional subcutaneous (s.c.) immunization using a mouse model of pulmonary tuberculosis. Although significantly improved protection in the lung was seen at early time points (2 and 4 months post-vaccination) for i.n. BC...
Source: Clinical and Vaccine Immunology - August 20, 2014 Category: Allergy & Immunology Authors: Derrick SC, Kolibab K, Yang A, Morris SL Tags: Clin Vaccine Immunol Source Type: research

Exercise testing and training in people with Huntington's disease.
CONCLUSIONS: There was a large variability in the observed metabolic and physiological responses to exercise in people with HD. The observed exercise responses suggest that altered exercise prescription parameters may be required for people with HD and that exercise response and factors' affecting this requires further investigation. PMID: 25142278 [PubMed - as supplied by publisher] (Source: Clinical Rehabilitation)
Source: Clinical Rehabilitation - August 20, 2014 Category: Rehabilitation Authors: Dawes H, Collett J, Debono K, Quinn L, Jones K, Kelson M, Simpson S, Playle R, Backx K, Wasley D, Nemeth A, Rosser A, Izardi H, Busse M Tags: Clin Rehabil Source Type: research

Preclinical pharmacology and toxicology study of Ad-hTERT-E1a-Apoptin, a novel dual cancer-specific oncolytic adenovirus.
In this study, the preclinical safety profiles of Ad-hTERT-E1a-Apoptin in animal models were investigated. At doses of 5.0×10(8), 2.5×10(9), and 1.25×10(10) viral particles (VP)/kg, Ad-hTERT-E1a-Apoptin had no adverse effects on mouse behavior, muscle cooperation, sedative effect, digestive system, and nervous systems, or on beagle cardiovascular and respiratory systems at 5.0×10(8), 2.5×10(9), and 1.25×10(10) VP/kg doses. In acute toxicity tests in mice, the maximum tolerated dose>5×10(10) VP/kg. There was no inflammation or ulceration at the injection sites within two weeks. In repeat-dose toxicological studies...
Source: Toxicology and Applied Pharmacology - August 20, 2014 Category: Toxicology Authors: Qi Y, Guo H, Hu N, He D, Zhang S, Chu Y, Huang Y, Li X, Sun L, Jin N Tags: Toxicol Appl Pharmacol Source Type: research

Observation of high recombination occurrence of Porcine Reproductive and Respiratory Syndrome Virus in field condition.
Abstract Recombination in Porcine reproductive and respiratory syndrome virus (PRRSV) is a well-documented phenomenon. A high recombination frequency has been reported in experimental conditions both in vitro and in vivo, and its role in driving viral evolution has been postulated by several authors. However field evidences are rare, mainly obtained from large-scale sampling and typically represented by single sequences rather than by groups of circulating "recombinant progenies". The present work was aimed to investigate the grey area between experimental studies and large scale epidemiological investigations. The...
Source: Virus Research - August 20, 2014 Category: Virology Authors: Franzo G, Cecchinato M, Martini M, Ceglie L, Gigli A, Drigo M Tags: Virus Res Source Type: research

Granulomatosis with polyangiitis (Wegener): Clinical aspects and treatment.
Abstract Granulomatosis with polyangiitis (GPA) is a systemic necrotizing vasculitis, which affects small- and medium-sized blood vessels and is often associated with cytoplasmic ANCA. GPA occurs in patients between 45 and 60years old of both genders, and is rarely observed in blacks. The prevalence of GPA increases along a south-north gradient in Europe (20 to 150/million). The main clinical characteristics involve the upper and/or lower respiratory tract and kidneys. Ear, nose and throat manifestations with recurrent sinusitis and crusting rhinorrhea are usually severe. Lung nodules are frequently seen, sometimes...
Source: Autoimmunity Reviews - August 20, 2014 Category: Allergy & Immunology Authors: Comarmond C, Cacoub P Tags: Autoimmun Rev Source Type: research

Body mass index change and atopic diseases are not always associated in children and adolescents.
CONCLUSION: These results indicate a nonsignificant trend between increased body weight and risk of atopic diseases. Aside from limitations owing to a small subgroup of obese participants and questionnaire-based asthma diagnosis, reasons might be related to an interaction between BMI and hormonal influences, age, and duration and severity of overweight. The results underline that BMI does not necessarily play a decisive role in the course of atopic diseases in all populations. PMID: 25150785 [PubMed - as supplied by publisher] (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - August 20, 2014 Category: Allergy & Immunology Authors: Kreißl S, Radon K, Dressel H, Genuneit J, Kellberger J, Nowak D, von Mutius E, Weiland SK, Weinmayr G, Windstetter D, Vogelberg C Tags: Ann Allergy Asthma Immunol Source Type: research

Two Decades' Experience With Interfacility Transport on Extracorporeal Membrane Oxygenation.
CONCLUSIONS: Interfacility transport on ECMO is feasible and can be accomplished safely in the critically ill. Survival of transported patients is comparable to age-matched and treatment-matched ECMO patients at large. PMID: 25149055 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - August 20, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Bryner B, Cooley E, Copenhaver W, Brierley K, Teman N, Landis D, Rycus P, Hemmila M, Napolitano LM, Haft J, Park PK, Bartlett RH Tags: Ann Thorac Surg Source Type: research

Spatial and volumetric changes of retroperitoneal sarcomas during pre-operative radiotherapy.
CONCLUSION: Inter-fraction CBCT provides important volumetric and positional information of RPS which may improve PreRT quality and prompt re-planning. Planning target volume may be reduced using online soft-tissue matching to account for interfractional displacements of GTVs. Important breathing motion occurred in superiorly placed RPS supporting the utility of 4D-CT planning. PMID: 25150633 [PubMed - as supplied by publisher] (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - August 20, 2014 Category: Radiology Authors: Wong P, Dickie C, Lee D, Chung P, O'Sullivan B, Letourneau D, Xu W, Swallow C, Gladdy R, Catton C Tags: Radiother Oncol Source Type: research

Fetal Growth Restriction Is Worse than Extreme Prematurity for the Developing Lung.
Conclusions: This study reports that VLGA-IUGR infants are at higher risk of neonatal mortality and CLD than both ELGA-AGA and VLGA-AGA infants. © 2014 S. Karger AG, Basel. PMID: 25170598 [PubMed - as supplied by publisher] (Source: Neonatology)
Source: Neonatology - August 20, 2014 Category: Perinatology & Neonatology Authors: Soudée S, Vuillemin L, Alberti C, Mohamed D, Becquet O, Farnoux C, Biran V, Baud O Tags: Neonatology Source Type: research

Deposition of Particles in Human Mouth–Throat Replicas and a USP Induction Port
Journal of Aerosol Medicine and Pulmonary Drug Delivery , Vol. 0, No. 0. (Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery)
Source: Journal of Aerosol Medicine and Pulmonary Drug Delivery - August 19, 2014 Category: Respiratory Medicine Tags: article Source Type: research

Compressive Forces and Computed Tomography–derived Positive End-expiratory Pressure in Acute Respiratory Distress Syndrome
Conclusions: Lung recruitability and CT scan–derived PEEP are unrelated. To overcome the compressive forces and to lift up the thoracic cage, a similar PEEP level is required in higher and lower recruiters (16.8 ± 4 vs. 16.6 ± 5.6, P = 1). (Source: Anesthesiology)
Source: Anesthesiology - August 19, 2014 Category: Anesthesiology Tags: Critical Care Medicine: Clinical Science Source Type: research

Two Studies on Reversal of Opioid-induced Respiratory Depression by BK-channel Blocker GAL021 in Human Volunteers
Conclusion: GAL021 produces respiratory stimulatory effects during opioid-induced respiratory depression with containment of opioid-analgesia and without any further increase of sedation. Further studies are needed to confirm these preliminary data. (Source: Anesthesiology)
Source: Anesthesiology - August 19, 2014 Category: Anesthesiology Tags: Perioperative Medicine: Clinical Science Source Type: research

Improved Subspace Estimation for Low-Rank Model-Based Accelerated Cardiac Imaging
Sparse sampling methods have emerged as effective tools to accelerate cardiac magnetic resonance imaging (MRI). Low-rank model-based cardiac imaging uses a predetermined temporal subspace for image reconstruction from highly undersampled $({bf k},{hbox{t}})$-space data and has been demonstrated effective for high-speed cardiac MRI. The accuracy of the temporal subspace is a key factor in these methods, yet little work has been published on data acquisition strategies to improve subspace estimation. This paper investigates the use of non-Cartesian ${bf k}$-space trajectories to replace the Cartesian trajectories that are om...
Source: IEEE Transactions on Biomedical Engineering - August 19, 2014 Category: Biomedical Engineering Source Type: research

One Bout of Calf Raises Induces Improvement of Mitochondrial Function in Claudicants
Introduction: Mitochondria in patients with PAD do not produce as much ATP as mitochondria in normally perfused muscle. Therefore patients with PAD do not only have a decreased supply of nutrients and oxygen, as a result of diseased arteries, but the concurrent mitochondrial respiratory defects also lead to an even lower ATP production from the amount of O2 present. (Source: European Journal of Vascular and Endovascular Surgery)
Source: European Journal of Vascular and Endovascular Surgery - August 19, 2014 Category: Surgery Authors: M. van Schaardenburgh, M. Wohlwend, Ø. Rognmo, E. Mattsson Tags: ESVS Abstracts: Stockholm 2014 Source Type: research

Staphylococcus aureus bio‐products: New biological roles for a pleurodesis agent
(Source: Respirology)
Source: Respirology - August 19, 2014 Category: Respiratory Medicine Authors: Ioannis Psallidas, Georgios T. Stathopoulos Tags: Editorial Source Type: research

Is the incidence of malignancy increased in patients with sarcoidosis? A systematic review and meta‐analysis
In conclusion, after accounting for possible detection bias and publication bias, there does not appear be a significant association between sarcoidosis and malignancy. (Source: Respirology)
Source: Respirology - August 19, 2014 Category: Respiratory Medicine Authors: Patompong Ungprasert, Narat Srivali, Karn Wijarnpreecha, Charat Thongprayoon, Wisit Cheungpasitporn, Eric L. Knight Tags: Review Source Type: research

Influence of distinct asthma phenotypes on lung function following weight loss in the obese
ConclusionsTH2‐low obese asthmatics appear to be characterized by increased small airway responsiveness and abnormalities in resting airway function that may persist following weight loss. However, this was not the case for TH2‐high obese asthmatics, highlighting the complex interplay between IgE status and asthma pathophysiology in obesity. (Source: Respirology)
Source: Respirology - August 19, 2014 Category: Respiratory Medicine Authors: David G. Chapman, Charles G. Irvin, David A. Kaminsky, Patrick M. Forgione, Jason H.T. Bates, Anne E. Dixon Tags: Original Article Source Type: research

Repeating pulmonary rehabilitation: Prevalence, predictors and outcomes
ConclusionsOne in five patients repeated PR, achieving clinically significant improvements in exercise tolerance and quality of life. Patients with small improvements in disease mastery after initial PR were more likely to repeat the programme and may benefit from earlier intervention or longer duration PR. (Source: Respirology)
Source: Respirology - August 19, 2014 Category: Respiratory Medicine Authors: Hazel Heng, Annemarie L. Lee, Anne E. Holland Tags: Original Article Source Type: research

Cross-resistance against RSV entry inhibitors [Microbiology]
In this study, we established a robust high-throughput drug screening protocol by... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - August 19, 2014 Category: Science Authors: Yan, D., Lee, S., Thakkar, V. D., Luo, M., Moore, M. L., Plemper, R. K. Tags: PNAS Plus Source Type: research