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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 7.

Viruses, Vol. 7, Pages 239-251: Identification of a Novel Human Rhinovirus C Type by Antibody Capture VIDISCA-454
In this study, antibody capture VIDISCA-454 (virus discovery cDNA-AFLP combined with Roche 454 high-throughput sequencing) resulted in the discovery of a novel type of rhinovirus C (RV-C). The virus has an RNA genome of at least 7054 nt and carries the characteristics of rhinovirus C species. The gene encoding viral protein 1, which is used for typing, has only 81% nucleotide sequence identity with the closest known RV-C type, and, therefore, the virus represents the first member of a novel type, named RV-C54. (Source: Viruses)
Source: Viruses - January 19, 2015 Category: Virology Authors: Seyed Mohammad Jazaeri FarsaniBas Oude MunninkMarta CanutiMartin DeijsMatthew CottenMaarten JebbinkJoost VerhoevenPaul KellamKatherine LoensHerman GoossensMargareta IevenLia van der Hoek Tags: Article Source Type: research

Maternal Prenatal Stress is Associated with the Infant Intestinal Microbiota
Although the underlying mechanisms remain unclear, an increasing number of studies link maternal prenatal stress to infant physical development and health, and psychological functioning and behavior. Stress during pregnancy predisposes to premature birth and low birth weight (Mulder et al., 2002; Beydoun and Saftlas, 2008), eczema (Sausenthaler et al., 2009), asthma (Cookson et al., 2009), and respiratory, general and skin illnesses (Beijers et al., 2010). Regarding psychological functioning and behavior, children of prenatally stressed mothers often show more impulsivity, anxiety problems, ADHD symptoms, and worse cogniti...
Source: Psychoneuroendocrinology - January 19, 2015 Category: Psychiatry Authors: Maartje A.C. Zijlmans, Katri Korpela, J. Marianne Riksen-Walraven, Willem M. de Vos, Carolina de Weerth Source Type: research

Resveratrol plus carboxymethyl‐β‐glucan may affect respiratory infections in children with allergic rhinitis
(Source: Pediatric Allergy and Immunology)
Source: Pediatric Allergy and Immunology - January 19, 2015 Category: Allergy & Immunology Authors: M. Miraglia Del Giudice, N. Maiello, F. Decimo, M. Capasso, G. Campana, S. Leonardi, G. Ciprandi Tags: Letters to the Editor Source Type: research

Ataxin-2 expands insight into the ALS clinical spectrum
Amyotrophic lateral sclerosis (ALS) is a relentless and devastating motor system degenerative disease, leading to death from respiratory failure typically within 3–5 years from first symptoms. Up to 15% of ALS is familial, with a Mendelian pattern of inheritance, while the remaining is a complex association between genetic susceptibility and environmental exposure.1–3 There is evolving evidence of population-based differences in genetic susceptibility, rendering the identification of robust associations among individual susceptibility genes and clinical disease symptoms challenging. However, the identification ...
Source: Neurology - January 19, 2015 Category: Neurology Authors: Bonini, N. M., Hardiman, O. Tags: Prognosis, Amyotrophic lateral sclerosis, Natural history studies (prognosis) EDITORIALS Source Type: research

Are You Covered? Safe Practices for the use of Personal Protective Equipment
Emergency nurses frequently encounter patients with a known or suspected infectious illness. To prevent the spread of infection and injury, emergency nurses must be well prepared to appropriately select and use personal protective equipment (PPE). Furthermore, emergency nurses must have readily available access to PPE, as well as effective and timely training, including routine fit testing for respiratory protection.1,2 According to the Occupational Safety & Health Administration (OSHA), when PPE is required, training for health care personnel must include the identification of the correct PPE; how to properly put on (don)...
Source: Journal of Emergency Nursing: JEN - January 19, 2015 Category: Nursing Authors: Anna Maria Valdez Tags: Injury Prevention Source Type: research

Evaluation of mold exposure in cystic fibrosis patients' dwellings and allergic bronchopulmonary risk
Very few studies have been conducted on cystic fibrosis (CF) patients' exposure to the indoor environment and, to our knowledge, there are no studies dealing with the link between specific fungal environmental exposure at home and fungal colonization resulting in allergic bronchopulmonary aspergillosis (ABPA). Fungal exposure of CF adult patients with ABPA (n=4) with fungal sensitization (n=7) and with no ABPA (n=5) was assessed in 16 homes by dust sampling with electrostatic dust fall collectors (EDCs). (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - January 19, 2015 Category: Respiratory Medicine Authors: Steffi Rocchi, Bénédicte Richaud-Thiriez, Coralie Barrera, Frédéric Grenouillet, Jean-Charles Dalphin, Laurence Millon, Gabriel Reboux Tags: Short Communication Source Type: research

Short-term effects of physiotherapy on ventilation inhomogeneity in cystic fibrosis patients with a wide range of lung disease severity
Lung clearance index (LCI) is increasingly used as a study endpoint for therapeutic interventions in cystic fibrosis (CF) patients. We set out to assess the effect of chest physiotherapy on ventilation inhomogeneity in clinically stable patients with CF lung disease of varying severity. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - January 19, 2015 Category: Respiratory Medicine Authors: A. Pfleger, M. Steinbacher, G. Schwantzer, E. Weinhandl, M. Wagner, E. Eber Tags: Original Article Source Type: research

Plasma irisin in runners and nonrunners: no favorable metabolic associations in humans
Abstract Irisin is a hormone which mimics the favorable metabolic effects associated with regular exercise, by converting subcutaneous white fat into brownish fat, in rodents. Thirty‐three human subjects (16 runners, 17 nonrunners) were measured for: resting energy expenditure (REE), body composition, VO2 Peak test, [irisin]p, and plasma metabolic profile. Nine female nonrunners then participated in a 10‐week supervised 5 km training program and tested after the race. Two runners underwent 18F‐FDG‐PET scans to quantify brown fat. No gender or age (28 ± 10 years) differences noted between matched cohorts. Runne...
Source: Physiological Reports - January 19, 2015 Category: Physiology Authors: Tamara Hew‐Butler, Kristin Landis‐Piwowar, Gregory Byrd, Max Seimer, Nicole Seigneurie, Brigid Byrd, Otto Muzik Tags: Original Research Source Type: research

FDA Approval: Siltuximab for the Treatment of Patients with Multicentric Castleman Disease.
Abstract On April 22, 2014, the FDA granted full approval to siltuximab (SYLVANT for Injection, Janssen Biotech, Inc.), a chimeric human-mouse monoclonal antibody to interleukin-6, for the treatment of patients with multicentric Castleman disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. The approval was primarily based on the results of a randomized, double-blind trial in which 79 symptomatic patients with MCD were allocated (2:1) to siltuximab plus best supportive care (BSC) or to placebo plus BSC. The primary efficacy endpoint was the proportion of patien...
Source: Clinical Cancer Research - January 19, 2015 Category: Cancer & Oncology Authors: Deisseroth A, Ko CW, Nie L, Fourie Zirkelbach J, Zhao L, Bullock J, Mehrotra N, Del Valle P, Saber H, Sheth C, Gehrke B, Justice R, Farrell A, Pazdur R Tags: Clin Cancer Res Source Type: research

House dust mite reduction and avoidance measures for treating eczema.
CONCLUSIONS: We were unable to determine clear implications to inform clinical practice from the very low-quality evidence currently available. The modest treatment responses reported were in people with atopic eczema, specifically with sensitivity to one or more aeroallergens. Thus, their use in the eczema population as a whole is unknown. High-quality long-term trials of single, easy-to-administer house dust mite reduction or avoidance measures are worth pursuing. PMID: 25598014 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - January 19, 2015 Category: Journals (General) Authors: Nankervis H, Pynn EV, Boyle RJ, Rushton L, Williams HC, Hewson DM, Platts-Mills T Tags: Cochrane Database Syst Rev Source Type: research

Where there's smoke, there's respiratory risk.
PMID: 25602003 [PubMed - as supplied by publisher] (Source: cmaj)
Source: cmaj - January 19, 2015 Category: Journals (General) Authors: Wanniarachige D Tags: CMAJ Source Type: research

A case of bronchial atresia.
PMID: 25614380 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - January 19, 2015 Category: Respiratory Medicine Authors: Fernandez Rodriguez L, Fernandez-Velilla M, Torres Sanchez I Tags: Arch Bronconeumol Source Type: research

Conservative Approach in Bronchial Artery Aneurysm Rupture: A Therapeutic Option.
PMID: 25614379 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - January 19, 2015 Category: Respiratory Medicine Authors: Divisi D, de Vico A, Crisci R Tags: Arch Bronconeumol Source Type: research

Pleural Effusion Secondary to Actinomyces Infection as a Late Complication of Laparoscopic Cholecystectomy.
PMID: 25614378 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - January 19, 2015 Category: Respiratory Medicine Authors: Díaz Campos RM, López-Medrano F, Lalueza A, Granados Caballero F, Villena Garrido V Tags: Arch Bronconeumol Source Type: research

Spanish Consensus on the Prevention and Treatment of Pseudomonas aeruginosa Bronchial Infections in Cystic Fibrosis Patients.
racia J, Solé A, en representación del Grupo Español de Consenso del Tratamiento Antimicrobiano en el Paciente con Fibrosis Quística Abstract Pseudomonas aeruginosa is the main pathogen in bronchopulmonary infections in cystic fibrosis (CF) patients. It can only be eradicated at early infection stages while reduction of its bacterial load is the therapeutic goal during chronic infection or exacerbations. Neonatal screening and pharmacokinetic/pharmacodynamic knowledge has modified the management of CF-patients. A culture based microbiological follow-up should be performed in patients with no infection with P.ae...
Source: Archivos de Bronconeumologia - January 19, 2015 Category: Respiratory Medicine Authors: Cantón R, Máiz L, Escribano A, Olveira C, Oliver A, Asensio O, Gartner S, Roma E, Quintana-Gallego E, Salcedo A, Girón R, Barrio MI, Pastor MD, Prados C, Martínez-Martínez MT, Barberán J, Castón JJ, Martínez-Martínez L, Poveda JL, Vázquez C, de Tags: Arch Bronconeumol Source Type: research

Pathogenic Mechanisms in Chronic Obstructive Pulmonary Disease Due to Biomass Smoke Exposure.
Abstract Chronic obstructive pulmonary disease (COPD) mortality and morbidity have increased significantly worldwide in recent decades. Although cigarette smoke is still considered the main risk factor for the development of the disease, estimates suggest that between 25% and 33% of COPD patients are non-smokers. Among the factors that may increase the risk of developing COPD, biomass smoke has been proposed as one of the most important, affecting especially women and children in developing countries. Despite the epidemiological evidence linking exposure to biomass smoke with adverse health effects, the specific ce...
Source: Archivos de Bronconeumologia - January 19, 2015 Category: Respiratory Medicine Authors: Silva R, Oyarzún M, Olloquequi J Tags: Arch Bronconeumol Source Type: research

Biological Marker Analysis as Part of The CIBERES-RTIC Cancer-SEPAR Strategic Project on Lung Cancer.
Abstract The aim of the Clinical and Molecular Staging of Stage I-IIp Lung Cancer Project is to identify molecular variables that improve the prognostic and predictive accuracy of TMN classification in stage I/IIp non-small cell lung cancer (NSCLC). Clinical data and lung tissue, tumor and blood samples will be collected from 3 patient cohorts created for this purpose. The prognostic protein signature will be validated from these samples, and micro-RNA, ALK, Ros1, Pdl-1, and TKT, TKTL1 y G6PD expression will be analyzed. Tissue inflammatory markers and stromal cell markers will also be analyzed. Methylation of p16,...
Source: Archivos de Bronconeumologia - January 19, 2015 Category: Respiratory Medicine Authors: Monsó E, Montuenga LM, Sánchez de Cos J, Villena C, por el Grupo Colaborativo en Cáncer de Pulmón CIBERES-RTICC-SEPAR-Plataforma Biobanco Pulmonar Tags: Arch Bronconeumol Source Type: research

Electron Tunneling Rates in Respiratory Complex I Are Tuned for Efficient Energy Conversion.
Abstract Respiratory complex I converts the free energy of ubiquinone reduction by NADH into a proton motive force, a redox reaction catalyzed by flavin mononucleotide(FMN) and a chain of seven iron-sulfur centers. Electron transfer rates between the centers were determined by ultrafast freeze-quenching and analysis by EPR and UV/Vis spectroscopy. The complex rapidly oxidizes three NADH molecules. The electron-tunneling rate between the most distant centers in the middle of the chain depends on the redox state of center N2 at the end of the chain, and is sixfold slower when N2 is reduced. The conformational changes...
Source: Angewandte Chemie - January 19, 2015 Category: Chemistry Authors: de Vries S, Dörner K, Strampraad MJ, Friedrich T Tags: Angew Chem Int Ed Engl Source Type: research

Effects of food and alcohol on pharmacokinetics of hydrocodone ER
Farr SJ, Robinson CY, Rubino CM (Source: International Journal of COPD)
Source: International Journal of COPD - January 18, 2015 Category: Respiratory Medicine Source Type: research

[New dry powder inhalers].
Abstract The most recently approved DPI's - Ellipta™ and NEXThaler® are the most modern inhalers on the market. Both are flow independent in the physiological range of flows seen in patients with asthma and/or COPD. Both require three actions (open-load -inhaler) for a successful inhalation. The Ellipta™ inhaler is the first DPI, which enables simultaneous delivery of two compounds without need for co-formulation. NEXThaler® is the only DPI on the market delivering extra fine aerosol (MMAD < 2 μm) of a combined inhalation product of inhaled corticosteroid and long-action b2-agonist. Both have been approve...
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Emeryk A, Pirożyński M Tags: Pneumonol Alergol Pol Source Type: research

[Assessment of respiratory function in the qualification for lung cancer surgery].
Abstract Surgery is the treatment of choice in patients with a diagnosis of non-small cell lung cancer (NSCLC). A pivotal of eligibility for resection is the early stage of the disease and histopathological assessment. The performance status and comorbidities in population, predominated by elderly patients, also influence the therapeutic decisions. In some lung cancer patients COPD coexists, characterized by a decrease in lung function. Then the preoperative evaluation is particularly important, for both the risk of postoperative complications, lung function and quality of life postoperatively. Recently several rec...
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Franczuk M, Wesołowski S Tags: Pneumonol Alergol Pol Source Type: research

[Application of basophil activation test in diagnosing aspirin hypersensitivity].
We present a case of identification of the culprit drug which caused an anaphylactic reaction. PMID: 25577537 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Gawinowska M Tags: Pneumonol Alergol Pol Source Type: research

[Diagnostic and therapeutic difficulties in mediastinal fibromatosis. Case report].
Abstract Mediastinal fibromatosis is a very rare mesenchymal tumor originated from fibrous tissue. A case of 26-year old men with mediastinal tumor causes respiratory insufficiency and dysphagia is described. This sympthoms occured due to esophageal impression and infiltration with occlusion of main left bronchus by mediastinal tumor. Ethiology of the tumor was established based on histopathology assesment of the tissue samples taken during explorative thoracotomy after 3 years and many other diagnostic procedures undertaken. The authors describe difficulties in diagnosis of mediastinal tumors, especially those rar...
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Wojtyś ME, Alchimowicz J, Waloszczyk P, Wójcik N, Grodzki T Tags: Pneumonol Alergol Pol Source Type: research

[Vascular ring: a rare cause of dyspnea in an elderly male patient. Case report].
Abstract Shortness of breath (dyspnea) and changes present in X-rays of the chest are most frequent symptoms indicating further pulmonary diagnostic. Presented is the case of 71-year-old patient reffered from general practitioner due to exacerbation of dyspnea and abnormalities present in the chest X-ray.The patient has been treated for ischemic heart disease and arrythmia for a couple of years.Three-dimensional CT of the chest revealed a vascular ring of aorta.It is a defect characterized by a faulty flow of large vascular trunks, which built a cardiovascular ring that partially or completely enricle the structure...
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Orwaldi M Tags: Pneumonol Alergol Pol Source Type: research

Leflunomide-induced acute interstitial pneumonia in a patient treated for rheumatoid arthritis.
We present a patient with RA treated with leflunomide, in whom leflunomide lung injury had a fatal outcome. Potential risk factors for pulmonary complications of leflunomide treatment and the management of patients with leflunomide lung injury are discussed. PMID: 25577534 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Maskey-Warzęchowska M, Karwat K, Szczepankiewicz B, Langfort R, Szołkowska M, Chazan R Tags: Pneumonol Alergol Pol Source Type: research

[Primary pulmonary mucosa-associated lymphoid tissue lymphoma: a case report].
We present the case of primary pulmonary mucosa-associated lymphoid tissue lymphoma. A 76-year-old man with a history of heavy smoking (22.5 pack years) was admitted to the hospital for a further diagnostics of an abnormal finding in the right lung visualized on the chest X-ray. The diagnostic process, including imagining studies did not reveal the etiology of a lesion in the right lung. The patient was qualified for surgical diagnostics. The histological finding confirmed extranodal marginal low-grade B-cell lymphoma of mucosa -associated lymphoid tissue. PMID: 25577533 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Kubisa B, Bocheńska A, Piotrowska M, Dec P, Lesińska A, Kubisa A, Wójcik J, Pieróg J, Grodzki T Tags: Pneumonol Alergol Pol Source Type: research

Bird fancier's lung: clinical-radiological presentation in 15 cases.
CONCLUSIONS: BFL can exhibit a wide range of radiological patterns, and a high index of suspicion must be maintained, with particular attention to detailed exposure history in every case of interstitial lung disease. PMID: 25577532 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Kumar R, Singh M Tags: Pneumonol Alergol Pol Source Type: research

Lung-heart clinical crosstalk in the course of COPD exacerbation.
CONCLUSIONS: Pulmonary hyperinflation and bronchial obstruction may be reduced by effective COPD exacerbation treatment and are accompanied by clinical improvement. The mPAP reduction observed in the course of treatment was not correlated with the results of 6MWT and MRC score. PMID: 25577531 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Skoczyński S, Mizia-Stec K, Semik-Orzech A, Sozańska E, Brożek G, Pierzchała W Tags: Pneumonol Alergol Pol Source Type: research

Tuberculosis among the homeless and inmates kept in custody and in penitentiary institutions in the Silesia region.
CONCLUSIONS: The health project enabled effective detection of tuberculosis in risk groups and should be continued in the following years. The set of the applied diagnostic methods allowed the detection of in the studied subpopulations people suffering from tuberculosis. Patients were treated with antituberculosis drugs that would stop them from spreading the disease to other people. PMID: 25577530 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Pendzich J, Maksymowicz-Mazur W, Pawłowska J, Filipczyk Ł, Kulawik I, Zientek J, Kozielski J Tags: Pneumonol Alergol Pol Source Type: research

Fatigue in patients with inactive sarcoidosis does not correlate with lung ventilation ability or walking distance. Pilot Study.
CONCLUSIONS: Fatigue in patients with sarcoidosis does not correlate with the results of lung function tests or with walking distance in 6MWT. PMID: 25577529 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Zieleźnik K, Jastrzębski D, Ziora D Tags: Pneumonol Alergol Pol Source Type: research

Chronic obstructive pulmonary disease in the awareness of Polish society. Report from the public opinion survey by the Polish Respiratory Society and TNS Polska.
CONCLUSIONS: There is an urgent need for widespread public education on preventive measures. Study results support the need of educating both healthy subjects and patients with COPD as to how effectively reduce the risk of developing the disease. One third of all respondents has no assumptions in this regard (i.e. explicitly declares having no knowledge at all on the subject), and more than 40% subjects have various misconceptions. Educators should therefore spread information about the disease but also correct these misconceptions. PMID: 25577528 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Śliwiński P, Puchalski K Tags: Pneumonol Alergol Pol Source Type: research

Cystic fibrosis and beckwith-wiedemann syndrome: a case report.
We describe for the first time the association of CF and Beckwith-Wiedemann syndrome (BWS). BWS is a genetic disorder commonly characterized by overgrowth. The most common features of BWS include macrosomia, macroglossia, abdominal wall defects, an increased risk for childhood tumors, kidney abnormalities, hypoglycemia in the newborn period and unusual ear creases or pits. PMID: 25584105 [PubMed] (Source: Clin Med Res)
Source: Clin Med Res - January 18, 2015 Category: Research Authors: Aguiar C, Correia-Costa L, Eden P, Guedes-Vaz L Tags: J Clin Med Res Source Type: research

A comparison of the predictive accuracy of three screening models for pulmonary arterial hypertension in systemic sclerosis
Conclusions: In this cohort, the DETECT and ASIG algorithms out-perform the ESC/ERS guidelines, detecting all patients with PAH. The ESC/ERS guidelines have limitations in the absence of a TR jet. Ultimately, the choice of SSc-PAH screening algorithm will also depend on cost and ease of application. (Source: BioMed Central)
Source: BioMed Central - January 18, 2015 Category: Journals (General) Authors: Yanjie HaoVivek ThakkarWendy StevensKathleen MorrisroeDavid PriorCandice RabusaPeter YoussefEli GabbayJanet RoddyJennifer WalkerJane ZochlingJoanne SahharPeter NashSusan LesterMaureen RischmuellerSusanna M ProudmanMandana Nikpour Source Type: research

Exploratory study comparing dysautonomia between asthmatic and non-asthmatic elite swimmers
Conclusions No significant differences were observed between asthmatic and non-asthmatic swimmers regarding parasympathetic parameters, but among those with relevant AHR an association was found. Although limited by the sample size, these findings support the relation between dysautonomia and AHR in asthmatic swimmers. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - January 18, 2015 Category: Respiratory Medicine Source Type: research

The overall impact of COPD (CAT) and BODE index on COPD male patients: correlation?
Conclusion As pre-existent data in the literature (exacerbations and benefit of rehabilitation in COPD), the positive correlations found with BODE index reinforce the discriminative validity of CAT as a complement in the evaluation of what the true impact of COPD is on a patient's daily life. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - January 18, 2015 Category: Respiratory Medicine Source Type: research

Surgical treatment of scoliosis in Rubinstein-Taybi syndrome type 2: a case report
Conclusion: Scoliosis can develop in young children with Rubinstein-Taybi syndrome type 2, with the deformity deteriorating around the pubertal growth spurt. Surgical treatment can correct the deformity, balance the spine and prevent mechanical back pain. It can also stabilize the chest area and avoid respiratory complications developing as the scoliosis progresses, which can result in severe restrictive pulmonary disease. The use of single concave instrumentation is indicated in very slim patients with poor muscle bulk; in our patient, this produced satisfactory deformity correction and a favorable outcome at completion o...
Source: BioMed Central - January 18, 2015 Category: Journals (General) Authors: Nikolaos BounakisChristos KarampalisHilary SharpAthanasios I Tsirikos Source Type: research

Isolated and synergistic effects of PM10 and average temperature on cardiovascular and respiratory mortality
CONCLUSIONS The positive association standardized in the Poisson regression model for pollutant concentration is not confounded by temperature, and the effect of temperature is not confounded by the pollutant levels in the time-series analysis. The simultaneous exposure to different levels of environmental factors can create synergistic effects that are as disturbing as those caused by extreme concentrations. OBJETIVO Analisar o efeito da poluição do ar e da temperatura na mortalidade por doenças cardiovasculares e respiratórias. MÉTODOS Foram analisados os efeitos da temperatura e do material particulado com diâmet...
Source: Revista de Saude Publica - January 17, 2015 Category: Global & Universal Source Type: research

Review of Secondary Health Conditions in Postpolio Syndrome: Prevalence and Effects of Aging
ConclusionsLongitudinal research is needed to understand the course of health conditions and the impact of multiple secondary conditions in people aging with PPS. Efforts are also needed to develop and test the efficacy of interventions to prevent these secondary health conditions or reduce their negative impact. (Source: American Journal of Physical Medicine and Rehabilitation)
Source: American Journal of Physical Medicine and Rehabilitation - January 17, 2015 Category: Rehabilitation Tags: Literature Review Source Type: research

Cesarean Section and Hospitalization for Respiratory Syncytial Virus Infection
No abstract available (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - January 17, 2015 Category: Infectious Diseases Tags: Letters to the Editor Source Type: research

Caesarean Section and Hospitalization for Respiratory Syncytial Virus Infection: A Population-based Study
Conclusion: Delivery by caesarian section is associated with an increased risk of hospitalization for RSV infection. This effect continues at least throughout the first 2 years of life. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - January 17, 2015 Category: Infectious Diseases Tags: Original Studies Source Type: research

Human Parechovirus Infection in Neonatal Intensive Care
Conclusions: We found an HPeV infection rate of 13% in infants being tested for late onset sepsis. HPeV should be considered as a possible cause of sepsis-like symptoms in preterm infants. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - January 17, 2015 Category: Infectious Diseases Tags: Original Studies Source Type: research

Prone Positioning in Acute Respiratory Distress Syndrome
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - January 17, 2015 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Paring Down Cytomegalovirus’s Role in Acute Respiratory Distress Syndrome Outcome*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - January 17, 2015 Category: Emergency Medicine Tags: Editorials Source Type: research

The PaO2/FIO2 Ratio Categorization of Patients With Acute Respiratory Distress Syndrome Is Suboptimal*
No abstract available (Source: Critical Care Medicine)
Source: Critical Care Medicine - January 17, 2015 Category: Emergency Medicine Tags: Editorials Source Type: research