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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 7.

Increasing prevalence of asthma, respiratory symptoms, and allergic diseases: Four repeated surveys from 1993-2014
Published data shows different prevalence trends depending on the region of Europe. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - May 16, 2015 Category: Respiratory Medicine Authors: Grzegorz Brozek, Joshua Lawson, Dawid Szumilas, Jan Zejda Source Type: research

Expression of a single siRNA against a conserved region of NP gene strongly inhibits in vitro replication of different Influenza A virus strains of avian and swine origin.
In conclusion, these findings reveal new siRNA sequences able to inhibit Influenza A virus replication and provide a basis for the development of siRNAs as prophylaxis and therapy for influenza infection both in humans and animals. PMID: 25986248 [PubMed - as supplied by publisher] (Source: Antiviral Research)
Source: Antiviral Research - May 16, 2015 Category: Virology Authors: Stoppani E, Bassi I, Dotti S, Lizier M, Ferrari M, Lucchini F Tags: Antiviral Res Source Type: research

Comparative ventilatory strategies of acclimated rats and burrowing plateau pika (Ochotona curzoniae) in response to hypoxic-hypercapnia.
The objective of this study was to compare the different ventilatory strategies that helps in coping with hypoxic-hypercapnia environment among two species: use acclimated rats and plateau pikas (Ochotona curzoniae) that live in Tibetan plateaus, and have been well adjusted to high altitude. Arterial blood samples taken at 4100m of elevation in acclimatized rats and adapted pikas revealed inter-species differences with lower haemoglobin and hematocrit and higher blood pH in pikas. A linear and significant increase in minute ventilation was observed in pikas, which help them to cope with hypoxic-hypercapnia. Pikas also disp...
Source: Comparative Biochemistry and Physiology. Part A, Molecular and integrative physiology. - May 16, 2015 Category: Physiology Authors: Pichon A, Voituron N, Bai Z, Jeton F, Tana W, Marchant D, Jin G, Richalet JP, Ge RL Tags: Comp Biochem Physiol A Mol Integr Physiol Source Type: research

Impact of Pulmonary Function Measurements on Long-Term Survival After Lobectomy for Stage I Non-Small Cell Lung Cancer.
CONCLUSIONS: Survival after lobectomy for patients with stage I non-small cell lung cancer is impacted by lower Dlco, which can be used in the risk and benefit assessment when choosing therapy. PMID: 25986099 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 16, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Berry MF, Jeffrey Yang CF, Hartwig MG, Tong BC, Harpole DH, D'Amico TA, Onaitis MW Tags: Ann Thorac Surg Source Type: research

Thymic hyperplasia and chylothorax
(Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - May 15, 2015 Category: Respiratory Medicine Authors: Kimberly M. Hartzell, Kathryn C. Hines, Wynton C. Hoover Tags: Case Report Source Type: research

Gene and Protein Expression of Fibronectin and Tenascin-C in Lung Samples from COPD Patients
Conclusions An enhanced lung gene expression of Fn was observed in COPD subjects compared to non-COPD subjects. No differences were found in Fn protein expression or in TnC gene or protein expression among groups. (Source: Lung)
Source: Lung - May 15, 2015 Category: Respiratory Medicine Source Type: research

Use of Activated Factor VII in Patients with Diffuse Alveolar Hemorrhage: A 10 Years Institutional Experience
Conclusion Activated Factor VII can achieve hemostasis in patients with diffuse alveolar hemorrhage. (Source: Lung)
Source: Lung - May 15, 2015 Category: Respiratory Medicine Source Type: research

Incidental Lung Volume Reduction Following Fulminant Pulmonary Hemorrhage in a Patient with Severe Emphysema
Abstract Endoscopic lung volume reduction is an emerging technique meant to improve lung function parameters, quality of life, and exercise tolerance in patients with severe lung emphysema. This is the first report of lung volume reduction by autologous blood in a patient with non-bullous lung emphysema. A 74-year-old woman with heterogeneous lung emphysema developed accidentally diffuse lobar bleeding immediately after valve placement. Due to persistent hemorrhage, the valves had to be removed shortly thereafter. Despite extraction of the valves, respiratory function of the patient improved rapidly indicated als...
Source: Lung - May 15, 2015 Category: Respiratory Medicine Source Type: research

The Impact of Chronic Cough: A Cross-Sectional European Survey
Conclusions Chronic cough has a negative impact on quality of life. Further work is needed to raise awareness, promote management strategies, develop effective treatments and consider the educational and support needs of patients with chronic cough. (Source: Lung)
Source: Lung - May 15, 2015 Category: Respiratory Medicine Source Type: research

Kinetics of microRNA Expression in Bronchoalveolar Lavage Fluid Samples
Abstract Levels of microRNAs (miRNAs) are increasingly assessed in biological fluids, for example, in samples obtained by bronchoalveolar lavage (BAL). “Post-collection kinetics” of miRNA expression levels, however, have not been investigated to date. In these experiments, we analyzed the dynamic expression profile of 5 different miRNAs (miR-17, miR-19b, miR-20b, miR-125a, and miR-223-3p) in BAL within the first 24 h following collection by routine bronchoscopy. miRNAs were quantified 0, 1, 4, 8, and 24 h after collection in samples that were kept at 4 °C or at room temperature. The expression of all five...
Source: Lung - May 15, 2015 Category: Respiratory Medicine Source Type: research

Clinical Outcomes in Patients with Acute Eosinophilic Pneumonia Not Treated with Corticosteroids
Conclusion AEP-associated symptoms and radiographic abnormalities were resolved completely within 2 weeks after diagnosis even when corticosteroid treatment was not initiated. However, these findings might be limited to relatively mild cases of AEP. (Source: Lung)
Source: Lung - May 15, 2015 Category: Respiratory Medicine Source Type: research

Circulating Tumor Cells in Small Cell Lung Cancer: Ex Vivo Expansion
(Source: Lung)
Source: Lung - May 15, 2015 Category: Respiratory Medicine Source Type: research

In Situ Evidence of Pulmonary Endothelial Activation in Patients with Granulomatosis with Polyangiitis and Systemic Sclerosis
Conclusion These observations are an evidence of in situ pulmonary vascular endothelial activation in lesions of GPA and SScl, adding information to the pathogenic knowledge of both diseases. (Source: Lung)
Source: Lung - May 15, 2015 Category: Respiratory Medicine Source Type: research

Positional obstructive sleep apnea in bariatric surgery patients: risk factor for postoperative cardiopulmonary complications?
Conclusion In terms of 30-day postoperative cardiopulmonary outcome, CPAP therapy is not indicated in mild (P)OSA patients scheduled for BS. (Source: Sleep and Breathing)
Source: Sleep and Breathing - May 15, 2015 Category: Respiratory Medicine Source Type: research

Inspiratory muscle training in patients with diabetic autonomic neuropathy: a randomized clinical trial
Abstract Aims and methods We evaluated the effects of an 8-week inspiratory muscle training (IMT, n = 5) or placebo IMT (P-IMT, n = 5) on maximal respiratory pressures, pulmonary function, functional capacity, and cardiac autonomic control in patients with type 2 diabetes and diabetic autonomic neuropathy (DAN). Results and conclusions The IMT group had a greater increase in maximum inspiratory pressure as compared to P-IMT (p < 0.05). The IMT improved inspiratory muscle strength in patients with DAN. (Source: Clinical Autonomic Research)
Source: Clinical Autonomic Research - May 15, 2015 Category: Research Source Type: research

Narrative review of primary care point-of-care testing (POCT) and antibacterial use in respiratory tract infection (RTI).
Abstract Antimicrobial resistance is a global problem and is being addressed through national strategies to improve diagnostics, develop new antimicrobials and promote antimicrobial stewardship. A narrative review of the literature was undertaken to ascertain the value of C reactive protein (CRP) and procalcitonin, measurements to guide antibacterial prescribing in adult patients presenting to GP practices with symptoms of respiratory tract infection (RTI). Studies that were included were randomised controlled trials, controlled before and after studies, cohort studies and economic evaluations. Many studies demonst...
Source: Respiratory Care - May 15, 2015 Category: Respiratory Medicine Authors: Cooke J, Butler C, Hopstaken R, Dryden MS, McNulty C, Hurding S, Moore M, Livermore DM Tags: BMJ Open Respir Res Source Type: research

Patients' and providers' perceptions of asthma and asthma care: a qualitative study
Journal of Asthma, Ahead of Print. (Source: Journal of Asthma)
Source: Journal of Asthma - May 15, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Impact of symptom management training among asthmatic children and adolescents on self-efficacy and disease course
Journal of Asthma, Ahead of Print. (Source: Journal of Asthma)
Source: Journal of Asthma - May 15, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Chronic thromboembolic pulmonary arterial hypertension: a review of the literature and novel therapeutic approaches
Expert Review of Respiratory Medicine, Ahead of Print. (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - May 15, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study
This study suggests that measurement of grip strength is a simple, inexpensive risk-stratifying method for all-cause death, cardiovascular death, and cardiovascular disease. Further research is needed to identify determinants of muscular strength and to test whether improvement in strength reduces mortality and cardiovascular disease. Funding Full funding sources listed at end of paper (see Acknowledgments). (Source: The Lancet)
Source: The Lancet - May 15, 2015 Category: Journals (General) Source Type: research

Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome
Abstract Human congenital central hypoventilation syndrome (CCHS), resulting from mutations in transcription factor PHOX2B, manifests with impaired responses to hypoxemia and hypercapnia especially during sleep. To identify brainstem structures developmentally affected in CCHS, we analyzed two postmortem neonatal-lethal cases with confirmed polyalanine repeat expansion (PARM) or Non-PARM (PHOX2B∆8) mutation of PHOX2B. Both human cases showed neuronal losses within the locus coeruleus (LC), which is important for central noradrenergic signaling. Using a conditionally active transgenic mouse model of the PHOX2B∆...
Source: Acta Neuropathologica - May 15, 2015 Category: Neurology Source Type: research

Health‐related quality of life in children with objectively‐diagnosed staple food allergy assessed with a disease‐specific questionnaire
ConclusionsUse of a disease‐specific questionnaire revealed that disease severity in children with objectively‐diagnosed allergy to the staple foods cow's milk, hen's egg and, or wheat is associated with worse health‐related quality of life. Use of a generic questionnaire confirmed that cases have worse health‐related quality of life than controls.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - May 15, 2015 Category: Pediatrics Authors: JLP Protudjer, SA Jansson, E Östblom, RJM Middelveld, S‐E Dahlén, S Ahlstedt, Tags: Regular Article Source Type: research

Has Neonatal Dialysis Become Morally Obligatory?: Lessons from Baby Doe
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - May 15, 2015 Category: Pediatrics Authors: Aaron Wightman, Jennifer Kett Tags: A Different View Source Type: research

Bronchial thermoplasty: a non‐pharmacological approach
ConclusionBronchial thermoplasty causes improvement in the quality of life, and causes reduction in the emergency room visit and exacerbation due to asthma. Long‐term safety has been established by various prospective studies. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 15, 2015 Category: Respiratory Medicine Authors: Saurabh Kumar Singh, Kamlesh Kumar Tiwari Tags: Review Article Source Type: research

Scrotal wall metastasis from a primary lung adenocarcinoma
Publication date: Available online 15 May 2015 Source:Respiratory Medicine Case Reports Author(s): Marie-Louise M. Coussa-Koniski , Pia A. Maalouf , Nehme E. Raad , Noha A. Bejjani This a case of a 77 years old male heavy smoker, known to have Combined Pulmonary Fibrosis and Emphysema complicated by a primary invasive adenocarcinoma of the lung with bone metastasis, who presented with a two weeks history of right inguino-scrotal pain and swelling. Imaging studies revealed a right paratesticular formation that appeared to involve the epididymis and the scrotal wall. A biopsy of the mass showed morphological and Immunophen...
Source: Respiratory Medicine Case Reports - May 15, 2015 Category: Respiratory Medicine Source Type: research

Successful treatment with carboplatin and nanoparticle albumin-bound paclitaxel in a patient with pulmonary spindle cell carcinoma
Discussion Preclinical models suggested that nab-PTX may reach the tumor microenvironment more efficiently than solvent-based paclitaxel (sb-PTX) and be preferentially taken up by cancer cells. Considering that there is no effective treatment for patients with pulmonary SpCC, nab-PTX may merit further investigation in patients with pulmonary SpCC. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - May 15, 2015 Category: Respiratory Medicine Source Type: research

Dark sputum: an atypical presentation of primary pulmonary malignant melanoma
We describe a case of primary lung melanoma with brain and skin metastases that presented with an initial clinical diagnosis of pneumonia. A 55-year-old white man presented with cough productive of dark sputum and fever. A chest x-ray showed a right lung infiltration. After failure to respond to usual treatment for pneumonia, bronchoscopy examination and CT scan revealed a right pulmonary mass. The CT-guided biopsy confirmed a diagnosis of malignant melanoma. The primary lung origin of the tumor was demonstrated by the characteristic junctional pattern of melanoma cells. Further evaluation revealed metastases in the brain ...
Source: Respiratory Medicine Case Reports - May 15, 2015 Category: Respiratory Medicine Source Type: research

Researchers identify mutations in familial pulmonary fibrosis
Publication date: Available online 13 May 2015 Source:The Lancet Respiratory Medicine Author(s): Hilary Marshall (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - May 15, 2015 Category: Respiratory Medicine Source Type: research

Calcium-sensing receptors linked to development of asthma
Publication date: Available online 13 May 2015 Source:The Lancet Respiratory Medicine Author(s): Sanjay Tanday (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - May 15, 2015 Category: Respiratory Medicine Source Type: research

Airway inflammation and ammonia exposure among female Palestinian hairdressers: a cross-sectional study
Conclusions Compared to unexposed controls, the hairdressers had signs of neutrophilic airway inflammation, higher eNO levels and higher CRP. The hairdressers were exposed to high concentrations of ammonia from hairdressing chemicals and their working conditions were unsatisfactory. (Source: Occupational and Environmental Medicine)
Source: Occupational and Environmental Medicine - May 15, 2015 Category: Occupational Health Authors: Nemer, M., Sikkeland, L. I. B., Kasem, M., Kristensen, P., Nijem, K., Bjertness, E., Skare, O., Bakke, B., Kongerud, J., Skogstad, M. Tags: Workplace Source Type: research

Diffuse alveolar damage associated mortality in selected acute respiratory distress syndrome patients with open lung biopsy
This study is designed to investigate the role of DAD in ARDS patients who underwent open lung biopsy. Methods: We retrospectively reviewed all ARDS patients who met the Berlin definition and underwent open lung biopsy from January 1999 to January 2014 in a referred medical center. DAD is characterized by hyaline membrane formation, lung edema, inflammation, hemorrhage and alveolar epithelial cell injury. Clinical data including baseline characteristics, severity of ARDS, clinical and pathological diagnoses, and survival outcomes were analyzed. Results: A total of 1838 patients with ARDS were identified and open lung biops...
Source: Critical Care - May 15, 2015 Category: Intensive Care Authors: Kuo-Chin KaoHan-Chung HuChih-Hao ChangChen-Yiu HungLi-Chung ChiuShih-Hong LiShih-Wei LinLi-Pang ChuangChih-Wei WangLi-Fu LiNing-Hung ChenCheng-Ta YangChung-Chi HuangYing-Huang Tsai Source Type: research

Hyperoxia activates ATM independent from mitochondrial ROS and dysfunction
Publication date: Available online 2 May 2015 Source:Redox Biology Author(s): Emily A. Resseguie , Rhonda J. Staversky , Paul S. Brookes , Michael A. O’Reilly High levels of oxygen (hyperoxia) are often used to treat individuals with respiratory distress, yet prolonged hyperoxia causes mitochondrial dysfunction and excessive reactive oxygen species (ROS) that can damage molecules such as DNA. Ataxia telangiectasia mutated (ATM) kinase is activated by nuclear DNA double strand breaks and delays hyperoxia-induced cell death through downstream targets p53 and p21. Evidence for its role in regulating mitochondrial function...
Source: Redox Biology - May 15, 2015 Category: Biology Source Type: research

Blockade of the dorsomedial hypothalamus and the perifornical area inhibits respiratory responses to arousing and stressful stimuli
The dorsomedial hypothalamus (DMH) and the perifornical area (DMH/PeF) is one of the key regions of central autonomic processing. Previous studies have established that this region contains neurons that may be involved in respiratory processing; however, this has never been tested in conscious animals. The aim of our study was to investigate the involvement of the DMH/PeF area in mediating respiratory responses to stressors of various intensities and duration. Adult male Wistar rats (n = 8) received microinjections of GABAA agonist muscimol or saline into the DMH/PeF bilaterally and were subjected to a respiratory recordin...
Source: AJP: Regulatory, Integrative and Comparative Physiology - May 15, 2015 Category: Physiology Authors: Bondarenko, E., Beig, M. I., Hodgson, D. M., Braga, V. A., Nalivaiko, E. Tags: Respiration Source Type: research

Impact of Respiratory Morbidities on Neurodevelopmental Outcome of Late Preterm Infants
Conclusion LPT with significant respiratory morbidities are at higher risk for long-term developmental delays, mainly affecting cognitive developmental domains.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 15, 2015 Category: Perinatology & Neonatology Authors: Wachtel, Elena V.Zaccario, MicheleMally, Pradeep Tags: Original Article Source Type: research

Control of a H1N1 Outbreak in a Correctional Facility in Central Taiwan
Conclusions H1N1 influenza spread rapidly in the correctional facility, and the use of oseltamivir maybe a practical intervention to control of H1N1 outbreak in a such a totally enclosed environment. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - May 15, 2015 Category: Microbiology Source Type: research

Solid and suspension microarrays for microbial diagnostics
Publication date: Available online 14 May 2015 Source:Methods in Microbiology Author(s): Steve Miller , Ulas Karaoz , Eoin Brodie , Sherry Dunbar Advancements in molecular technologies have provided new platforms that are being increasingly adopted for use in the clinical microbiology laboratory. Among these, microarray methods are particularly well suited for diagnostics as they allow multiplexing, or the ability to test for multiple targets simultaneously from the same specimen. Microarray technologies commonly used for the detection and identification of microbial targets include solid-state microarrays, electronic mi...
Source: Methods in Microbiology - May 15, 2015 Category: Microbiology Source Type: research

Identification and genome characterization of genotype B and genotype C bovine parainfluenza type 3 viruses isolated in the United States
Conclusions: This study clearly demonstrated that BPI3Vb and BPI3Vc strains, previously thought to be foreign to the U.S., are indeed circulating in domestic livestock herds. Based on virus neutralization using polyclonal antisera, there were antigenic differences between viruses from these genotypes and the BPI3Va viruses that are included in currently marketed bovine vaccines. Further study of these viruses is warranted to determine pathogenic potential and cross-protection afforded by vaccination. (Source: BMC Veterinary Research)
Source: BMC Veterinary Research - May 15, 2015 Category: Veterinary Research Authors: John NeillJulia RidpathBinu Valayudhan Source Type: research

Daptomycin-Induced Eosinophilic Pneumonia Treated With Intravenous Corticosteroids
Conclusion: Since this potentially life-threatening adverse effect of daptomycin appears more common than previously reported, clinicians should have a high level of suspicion in any patient with recent daptomycin exposure who presents with pulmonary symptoms. In many cases, this process is highly responsive to prompt initiation of corticosteroid therapy. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 15, 2015 Category: Drugs & Pharmacology Authors: Chiu, S.-Y., Faust, A. C., Dand, H. M. Tags: Adverse Drug Event Source Type: research

Candida Glabrata and Candida Tropicalis in an Immunocompetent Patient: A Case Report
Conclusion: It is understood that pneumonia is rarely caused by Candida species in patients who are admitted to the hospital. However, health care professionals should be aware that Candida pneumonia should be suspected as part of the differential diagnosis even in immunocompetent patients, particularly if they have recently traveled outside the United States. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 15, 2015 Category: Drugs & Pharmacology Authors: Hamilton, L. A., Lockhart, N. R., Crain, M. R. Tags: Case Report Source Type: research

Pediatric Extracorporeal Membrane Oxygenation: An Introduction for Emergency Medicine Physicians
Extracorporeal membrane oxygenation (ECMO) therapy has supported critically ill pediatric patients in the intensive care unit setting with cardiac and respiratory failure. This therapy is beginning to transition to the emergency department setting. (Source: The Journal of Emergency Medicine)
Source: The Journal of Emergency Medicine - May 15, 2015 Category: Emergency Medicine Authors: Lynn P. Gehrmann, John W. Hafner, Daniel L. Montgomery, Klayton W. Buckley, Randall S. Fortuna Tags: Clinical Review Source Type: research