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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 7.

Characterizing the epidemiology, virology, and clinical features of influenza in China’s first severe acute respiratory infection sentinel surveillance system, February 2011 – October 2013
Background: After the 2009 influenza A(H1N1)pdm09 pandemic, China established its first severe acute respiratory infections (SARI) sentinel surveillance system. Methods: We analyzed data from SARI cases in 10 hospitals in 10 provinces in China from February 2011 to October 2013. Results: Among 5,644 SARI cases, 330 (6%) were influenza-positive. Among these, 62% were influenza A and 38% were influenza B. Compared with influenza-negative cases, influenza-positive SARI cases had a higher median age (20.0 years vs.11.0, p = 0.003) and were more likely to have at least one underlying chronic medical condition (age adjusted...
Source: BMC Infectious Diseases - March 22, 2015 Category: Infectious Diseases Authors: Zhibin PengLuzhao FengGreene CarolynKaili WangGuozhong ZhuYequn ZhangJumei HuYiwei HuangHuiqiong PanNongjian GuoChunyan XingYanhui ChuZhaolong CaoDeshan YuLinling LiuZeling ChenFang ZengWen XuXin XiongXiuwei ChengHua GuoWu ChenLing LiHui JiangJiandong Zhe Source Type: research

Understanding Mortality and Epidemiological Transition in Goa
This article attempts to study the major features of Goa’s mortality transition over the last three decades. By using the deaths data from the International Classification of Diseases (ICD) in the Annual Reports of Registrar of Births and Deaths in Goa, an attempt is made here to understand the major causes of mortality influencing Goa’s epidemiological transition. Age structure of mortality, changes in cause composition of age-specific mortality, male-female mortality differences and disease death patterns are also studied. It emerges from the article that Goa has witnessed a phase of gradual reduction of infe...
Source: Journal of Health Management - March 22, 2015 Category: Health Management Authors: Borkar, S. M. Tags: Articles Source Type: research

Anaesthetic and sedative agents used for electrical cardioversion.
CONCLUSIONS: Few studies reported statistically significant results for our relevant outcomes, and most study authors concluded that both, or all, agents compared in individual studies were adequate for cardioversion procedures. It is our opinion that at present, there is no evidence to suggest that current anaesthetic practice for cardioversion should change. PMID: 25803543 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - March 22, 2015 Category: Journals (General) Authors: Lewis SR, Nicholson A, Reed SS, Kenth JJ, Alderson P, Smith AF Tags: Cochrane Database Syst Rev Source Type: research

Optimisation of quantitative lung SPECT applied to mild COPD: a software phantom simulation study
Conclusions A LEHR collimator and 125 99mTc MBq together with an optimal combination of cutoff frequency, number of updates and kernel size, gave the best result. Suboptimal selections of either cutoff frequency, number of updates and kernel size will reduce the imaging system’s ability to detect mild COPD in the lung phantom. (Source: EJNMMI Research)
Source: EJNMMI Research - March 22, 2015 Category: Radiology Source Type: research

Mitosis Trumps T Stage and Proposed International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification for Prognostic Value in Resected Stage 1 Lung Adenocarcinoma
Conclusion: In this study of resected stage 1 primary lung adenocarcinoma, we found mitotic index to be the only independent prognostic marker. It was more closely associated with outcome than either pathologic T stage or IASLC/ATS/ERS architecture-based classification. Further validation of concordance and reproducibility in reporting mitotic index, as well as validation of prognostic significance, needs to be undertaken in independent data sets. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - March 21, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research

Prognostic Impact and Clinicopathological Correlations of the Cribriform Pattern in Pulmonary Adenocarcinoma
Conclusions: Our data support the introduction of cpADC as a novel category into future morphology based on pulmonary ADC classifications. Further international studies are required to validate the reported clinicopathological associations of the cribriform pattern. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - March 21, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research

Estimation of the success rate of anesthetic management for thymectomy in patients with myasthenia gravis treated without muscle relaxants: a retrospective observational cohort study
Abstract Although maintaining anesthesia for myasthenia gravis (MG) with minimal muscle relaxants (MR) is common, the success rate of anesthetic management for MG without MR is not clear. We therefore retrospectively examined the success rate of anesthetic management for MG without MR among 66 consecutive cases of thymectomy for MG performed at our hospital between January 2004 and April 2010, before approval of using sugammadex. A total of 60 patients (90.9 %) were treated without MR (N group). Among the 60 cases, 17 (28.3 %) patients were not extubated in the operating room due to postoperative respiratory dep...
Source: Journal of Anesthesia - March 21, 2015 Category: Anesthesiology Source Type: research

Fatal cases of human infection with avian influenza A (H7N9) virus in Shanghai, China in 2013.
Authors: Shen Y, Lu H, Qi T, Gu Y, Xiang M, Lu S, Qu H, Zhang W, He J, Cao H, Ye J, Fang X, Wu X, Zhang Z Abstract We retrospectively reviewed the medical records of 17 fatal H7N9 cases in Shanghai in 2013, analyzed clinical variables and described their clinical and epidemiologic characteristics. The median age was 73 years, and 82.4% had underlying medical conditions. The most frequent symptoms were fever (100%), followed by productive cough (47.1%) and dry cough (35.5%). Thirteen (76.5%) patients had dyspnea or respiratory distress, five (29.4%) had shock, and four (23.5%) had acute kidney injury. Seventeen (100...
Source: BioScience Trends - March 21, 2015 Category: Biomedical Science Tags: Biosci Trends Source Type: research

An update on Middle East respiratory syndrome: 2 years later
Expert Review of Respiratory Medicine, Ahead of Print. (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - March 21, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Underlying Mechanisms for Coexisting Central and Obstructive Sleep Apnea: Nocturnal PaCO2 and Poor Sleep Quality Are Key Issues
We report a case exhibiting an overnight shift from obstructive to central events. The central sleep apnea component was related to sleep instability, hyperventilation and low nocturnal PaCO2. Both types of respiratory events were successfully treated with adaptive servoventilation.Respiration (Source: Respiration)
Source: Respiration - March 21, 2015 Category: Respiratory Medicine Source Type: research

Heart rate recovery after the 6‐min walk test is related to 6‐min walk distance and percutaneous oxygen saturation recovery in patients with COPD
Heart rate recovery (HRR) after maximal load exercise affects mortality in chronic obstructive pulmonary disease (COPD). However, the associations of clinical characteristics with HRR after the 6‐min walk test (6MWT), which is defined as a submaximal load test, remain unclear. We showed that HRR in patients with COPD after 6MWT was related to 6‐min walk distance and percutaneous oxygen saturation recovery. HRR after the 6MWT may be useful to assess exercise capacity in COPD. (Source: Respirology)
Source: Respirology - March 21, 2015 Category: Respiratory Medicine Authors: Ryota Shiroishi, Chika Kitagawa, Naomi Miyamoto, Nao Kakuno, Harumi Koyanagi, Naoto Rikitomi, Hideaki Senjyu Tags: Scientific Letter Source Type: research

Transcriptional mechanisms for differential expression of outer membrane cytochrome genes omcA and mtrC in Shewanella oneidensis MR-1
Conclusions: Taken together, the present results indicate that transcription of the mtr genes is regulated by multiple promoters and regulatory systems, including the CRP/cAMP-dependent regulatory system and yet-unidentified negative regulators. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - March 21, 2015 Category: Epidemiology Authors: Takuya KasaiAtsushi KouzumaHideaki NojiriKazuya Watanabe Source Type: research

Different clinical, virological, serological and tissue tropism outcomes of two new and one old Belgian type 1 subtype 1 porcine reproductive and respiratory virus (PRRSV) isolates
In this study, the pathogenic behavior of PRRSV 13V091 and 13V117, isolated in 2013 from two different Belgian farms with enzootic respiratory problems shortly after weaning in the nursery, were compared with the Belgian strain 07V063 isolated in 2007. Full-length genome sequencing was performed to identify their origin. Twelve weeks-old pigs were inoculated intranasally (IN) with 13V091, 13V117 or 07V063 (9 pigs/group). At 10 days post inoculation (dpi), 4 animals from each group were euthanized and tissues were collected for pathology, virological and serological analysis. 13V091 infection resulted in the highest respir...
Source: Veterinary Research - March 21, 2015 Category: Veterinary Research Source Type: research

Formulation, preclinical and clinical evaluation of a new submicronic arginine respiratory fluid for treatment of chronic obstructive pulmonary disorder
Publication date: Available online 20 March 2015 Source:Saudi Pharmaceutical Journal Author(s): Virendra Pratap Singh Rathor , Pradeep Chugh , Rashid Ali , Anuj Bhatnagar , Syed Ehtaishamul Haque , Aseem Bhatnagar , Gaurav Mittal Inhalational drugs often suffer from low pulmonary deposition due to their micronized size. Aim of present study was development and evaluation of a novel submicronic L-arginine respiratory fluid formulation for treatment of cardiopulmonary complications associated with chronic obstructive pulmonary disorder (COPD). Objectives were (a) to develop and characterize submicronic L-arginine respirato...
Source: Saudi Pharmaceutical Journal - March 21, 2015 Category: Drugs & Pharmacology Source Type: research

Sudden cardiac arrest in a child with nemaline myopathy
Conclusions: Congenital typical nemaline myopathy is not necessarily a static or very slowly progressive disorder and acute cardiac deterioration can lead to early death. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - March 21, 2015 Category: Pediatrics Authors: Lucia MarsegliaGabriella D¿AngeloSara MantiVincenzo SalpietroTeresa ArrigoVittorio CavallariEloisa Gitto Source Type: research

Steroid-sensitive nephrotic syndrome in children: triggers of relapse and evolving hypotheses on pathogenesis
Nephrotic syndrome remains the most common manifestation of glomerular disease in childhood. Minimal change nephropathy is the most common cause of the syndrome in children. Despite its initial high response rate to corticosteroids and its favorable prognosis, relapses are common leading to increased morbidity and cost of treatment.This review seeks to appraise the common triggers of relapse and to highlight the evolving hypotheses about the pathogenesis of the syndrome. Literature search was conducted through PubMed, Google web search and Cochrane Database of Systematic reviews using relevant search terms.Acute respirator...
Source: Italian Journal of Pediatrics - March 21, 2015 Category: Pediatrics Authors: Samuel Uwaezuoke Source Type: research

Duration of daily TV/screen watching with cardiovascular, respiratory, mental and psychiatric health: Scottish Health Survey, 2012-2013
The link of duration of TV and/or screen watching and chronic health conditions by subtypes is unclear. Therefore, the relationship between TV and/or screen watching hours and cardiovascular, respiratory, mental and psychiatric health and well-being (happiness) was assessed in an independent population-based survey to identify correlations of various hours with health conditions. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 21, 2015 Category: Cardiology Authors: Ivy Shiue Source Type: research

Low Interleukin (IL)-18 levels in sputum supernatants of patients with severe refractory asthma
Severe refractory asthma (SRA) is characterized by persistent asthma symptoms, amplified airway inflammation despite treatment with high dose inhaled steroids and increased airway bacterial colonization. Interleukin (IL)-18 is a pleiotropic pro-inflammatory cytokine that modulates airway inflammation. Furthermore, as a product of the inflammasome, IL-18 is involved in host defence against viral and bacterial stimuli by modulating the immune response. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - March 21, 2015 Category: Respiratory Medicine Authors: Nikoletta Rovina, Efrossini Dima, Petros Bakakos, Eleni Tseliou, Konstantina Kontogianni, Spyros Papiris, Antonia Koutsoukou, Nikolaos G. Koulouris, Stelios Loukides Source Type: research

Aureisphaera galaxeae gen. nov., sp. nov., a marine member of the family Flavobacteriaceae isolated from the hard coral Galaxea fascicularis.
Abstract A novel Gram-stain negative, spherical, non-motile, strictly aerobic, heterotrophic, yellow pigmented bacterium, designated strain 04OKA003-7(T) was isolated from the hard coral Galaxea fascicularis L. collected at Akajima, Okinawa, Japan. Phylogenetic analysis based on the 16S rRNA gene sequence revealed the novel isolate is affiliated with the family Flavobacteriaceae of the phylum Bacteroidetes and that it showed highest sequence similarity (92.9 %) to Vitellibacter aestuarii JC2436(T) and Aureitalea marina S1-66(T). The strain could be differentiated phenotypically from recognized members of the famil...
Source: Antonie van Leeuwenhoek - March 21, 2015 Category: Microbiology Authors: Yoon J, Yasumoto-Hirose M, Kasai H Tags: Antonie Van Leeuwenhoek Source Type: research

Sudden cardiac arrest in a child with nemaline myopathy
Conclusions Congenital typical nemaline myopathy is not necessarily a static or very slowly progressive disorder and acute cardiac deterioration can lead to early death. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - March 21, 2015 Category: Pediatrics Source Type: research

Vaccination-challenge studies with a Port Chalmers/73 (H3N2)-based swine influenza virus vaccine: Reflections on vaccine strain updates and on the vaccine potency test.
Abstract The human A/Port Chalmers/1/73 (H3N2) influenza virus strain, the supposed ancestor of European H3N2 swine influenza viruses (SIVs), was used in most commercial SIV vaccines in Europe until recently. If manufacturers want to update vaccine strains, they have to perform laborious intratracheal (IT) challenge experiments and demonstrate reduced virus titres in the lungs of vaccinated pigs. We aimed to examine (a) the ability of a Port Chalmers/73-based commercial vaccine to induce cross-protection against a contemporary European H3N2 SIV and serologic cross-reaction against H3N2 SIVs from Europe and North Am...
Source: Vaccine - March 21, 2015 Category: Allergy & Immunology Authors: De Vleeschauwer A, Qiu Y, Van Reeth K Tags: Vaccine Source Type: research

Bacterial phospholipases C as vaccine candidate antigens against cystic fibrosis respiratory pathogens: The Mycobacterium abscessus model.
CONCLUSIONS: MA-PLC DNA- and PLC protein-vaccinated mice cleared more rapidly M. abscessus than β-galactosidase DNA- or PBS- vaccinated mice in the context of CF. PLCs could constitute interesting vaccine targets against common PLC-producing CF pathogens like P. aeruginosa. PMID: 25804706 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - March 21, 2015 Category: Allergy & Immunology Authors: Le Moigne V, Rottman M, Goulard C, Barteau B, Poncin I, Soismier N, Canaan S, Pitard B, Gaillard JL, Herrmann JL Tags: Vaccine Source Type: research

Colonic sarcoidosis: Unusual onset of a systemic disease.
Abstract Sarcoidosis is a multisystem chronic inflammatory condition of unknown etiology that has the potential to involve every tissue in the body. Sarcoidosis in the gastrointestinal system, and particularly the colon, is very rare. Here, we report the case of a 57-year-old man with no previous diagnosis of sarcoidosis who presented with new onset of abdominal pain and constipation. A colonoscopy revealed that the abdominal pain was caused by an obstructing lesion in the cecum-ascending colon and lacked a clear histologic diagnosis. Radiologic investigation revealed concentric wall thickening of the cecum-ascendi...
Source: World Journal of Gastroenterology : WJG - March 21, 2015 Category: Gastroenterology Authors: Erra P, Crusco S, Nugnes L, Pollio AM, Di Pilla G, Biondi G, Vigliardi G Tags: World J Gastroenterol Source Type: research

[Spinal muscular atrophy and respiratory failure. How do primary care pediatricians act in a simulated scenario?]
CONCLUSIONS: When faced with a simulated SMA-1 infant with respiratory failure, PCP have difficulties in interacting with the family, and to involve it in the decision making process. Practical training of all pediatricians should include case scenarios with an ethical clinical problem. PMID: 25804552 [PubMed - as supplied by publisher] (Source: Anales de Pediatria)
Source: Anales de Pediatria - March 21, 2015 Category: Pediatrics Authors: Agra Tuñas MC, Sánchez Santos L, Busto Cuiñas M, Rodríguez Núñez A Tags: An Pediatr (Barc) Source Type: research

Self-sampling for community respiratory illness: a new tool for national virological surveillance.
PMID: 25788252 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 20, 2015 Category: Infectious Diseases Authors: Elliot AJ, Bermingham A, Charlett A, Lackenby A, Ellis J, Sadler C, Sebastianpillai P, Powers C, Foord D, Povey E, Evans B, Durnall H, Fleming DM, Brown D, Smith GE, Zambon M Tags: Euro Surveill Source Type: research

Comparison of bronchiolitis of human metapneumovirus and human respiratory syncytial virus.
Abstract PMID: 25790057 [PubMed - as supplied by publisher] (Source: Acta Virologica)
Source: Acta Virologica - March 20, 2015 Category: Infectious Diseases Authors: Wang Y, Ji W, Hao C, Yan YD, Shao X, Xu J Tags: Acta Virol Source Type: research

Expiration-Phase Template-Based Motion Correction of Free-Breathing Abdominal Dynamic Contrast Enhanced MRI
This paper studies a novel method to compensate for respiratory and peristaltic motions in abdominal dynamic contrast enhanced magnetic resonance imaging. The method consists of two steps: 1) expiration-phase “template” construction and retrospective gating of the data to the template; and 2) nonrigid registration of the gated volumes. Landmarks annotated by three experts were used to directly assess the registration performance. A tri-exponential function fit to time intensity curves from regions of interest was used to indirectly assess the performance. One of the parameters of the tri-exponential fit was u...
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Wavelet Augmented Cough Analysis for Rapid Childhood Pneumonia Diagnosis
Pneumonia is the cause of death for over a million children each year around the world, largely in resource poor regions such as sub-Saharan Africa and remote Asia. One of the biggest challenges faced by pneumonia endemic countries is the absence of a field deployable diagnostic tool that is rapid, low-cost and accurate. In this paper, we address this issue and propose a method to screen pneumonia based on the mathematical analysis of cough sounds. In particular, we propose a novel cough feature inspired by wavelet-based crackle detection work in lung sound analysis. These features are then combined with other mathematical...
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Assess Sleep Stage by Modern Signal Processing Techniques
In this paper, two modern adaptive signal processing techniques, empirical intrinsic geometry and synchrosqueezing transform, are applied to quantify different dynamical features of the respiratory and electroencephalographic signals. We show that the proposed features are theoretically rigorously supported, as well as capture the sleep information hidden inside the signals. The features are used as input to multiclass support vector machines with the radial basis function to automatically classify sleep stages. The effectiveness of the classification based on the proposed features is shown to be comparable to human expert...
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Risk Indicators for Air Leaks in Preterm Infants Exposed to Restrictive Use of Endotracheal Intubation
Objectives: To identify perinatal risk indicators for air leaks in preterm infants treated with a policy of restrictive use of endotracheal intubation based on sustained inflations followed by noninvasive ventilation in the delivery room. Methods: Perinatal variables and variables of respiratory support in the delivery room were analyzed retrospectively in a cohort of 297 inborn preterm infants with a gestational age (Source: Neonatology)
Source: Neonatology - March 20, 2015 Category: Perinatology & Neonatology Source Type: research

Ventilation in day‐care centres and sick leave among nursery children
This study suggests a relationship between sick leave among nursery children and ventilation in DCCs, as measured with the decay method. This article is protected by copyright. All rights reserved. (Source: Indoor Air)
Source: Indoor Air - March 20, 2015 Category: Occupational Health Authors: Barbara Kolarik, Zorana Jovanovic Andersen, Tobias Ibfelt, Eva Hoy Engelund, Eva Møller, Elvira Vaclavik Bräuner Tags: Original Article Source Type: research

Authors' Reply
Respiration (Source: Respiration)
Source: Respiration - March 20, 2015 Category: Respiratory Medicine Source Type: research

Artifacts, Noise and Interference: Much Ado about Ultrasound
Respiration (Source: Respiration)
Source: Respiration - March 20, 2015 Category: Respiratory Medicine Source Type: research

Pulmonary Oedema: An Unusual Aetiology
Respiration (Source: Respiration)
Source: Respiration - March 20, 2015 Category: Respiratory Medicine Source Type: research

Response to Disodium Etidronate Treatment in Three Siblings with Pulmonary Alveolar Microlithiasis
We report 3 siblings (an 11-year-old boy and 4-year-old twin girls) with PAM diagnosed by chest X-ray, thoracic high-resolution computed tomography, technetium-99m bone scan and bronchoalveolar lavage fluid findings. After the administration of DE (200 mg/day) for a 1-year period, 2 siblings showed radiological improvement, while 1 sibling did not. No drug side effects were observed within the treatment period.Respiration (Source: Respiration)
Source: Respiration - March 20, 2015 Category: Respiratory Medicine Source Type: research

MUC5AC and MUC5B enhance the characterization of mucinous adenocarcinomas of the lung and predict poor prognosis
ConclusionMUC5AC and MUC5B were specific makers for non‐TRU adenocarcinoma including both of central type adenocarcinoma and mucinous adenocarcinoma. We suggest that non‐TRU type adenocarcinoma presents poorer prognosis so that it should be regarded separately from TRU type adenocarcinoma.This article is protected by copyright. All rights reserved. (Source: Histopathology)
Source: Histopathology - March 20, 2015 Category: Pathology Authors: Young Keum Kim, Dong Hoon Shin, Kyung Bin Kim, Nari Shin, Won Young Park, Jung Hee Lee, Kyung Un Choi, Jee Yeon Kim, Chang Hun Lee, Mee Young Sol, Mi Hyun Kim Tags: Original Article Source Type: research

The effects of cardiopulmonary bypass on pulmonary function during robotic cardiac surgery.
CONCLUSIONS: In robotic cardiac surgery under the conditions of OLV and carbon dioxide pneumothorax, CPB worsened pulmonary function and tolerance to OLV and carbon dioxide pneumothorax. PMID: 25784166 [PubMed - in process] (Source: Perfusion)
Source: Perfusion - March 20, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Wang G, Xiao S, Gao C Tags: Perfusion Source Type: research

The effect of rapid palatal expansion on sleep bruxism in children
Conclusion Most bruxers (65 %) reduced their RMMA episode index after expansion, but sleep and respiratory variables remained unchanged. (Source: Sleep and Breathing)
Source: Sleep and Breathing - March 20, 2015 Category: Respiratory Medicine Source Type: research

Mechanical ventilation modes for respiratory distress syndrome in infants: a systematic review and network meta-analysis
Conclusion: Compared with the SIMV + PSV ventilation mode, the TCPL, HFOV, SIMV + VG and V-C ventilation modes are associated with lower mortality. (Source: Critical Care)
Source: Critical Care - March 20, 2015 Category: Intensive Care Authors: Changsong WangLibo GuoChunjie ChiXiaoyang WangLei GuoWeiwei WangNana ZhaoYibo WangZhaodi ZhangEnyou Li Source Type: research

Validation of overnight oximetry to diagnose patients with moderate to severe obstructive sleep apnea
This study evaluates validity of overnight pulse oximetry as a diagnostic tool for moderate to severe OSA patients. Methods: A total of 699 patients with possible OSA were recruited for overnight oximetry and PSG examination at the Sleep Center of a University Hospital from Jan. 2004 to Dec. 2005. By excluding 23 patients with poor oximetry recording, poor EEG signals, or respiratory artifacts resulting in a total recording time less than 3 hours; 12 patients with total sleeping time (TST) less than 1 hour, possibly because of insomnia; and 48 patients whose ages less than 20 or more than 85 years old, data of 616 patie...
Source: Epidemiologic Perspectives and Innovations - March 20, 2015 Category: Epidemiology Authors: Liang-Wen HangHsiang-Ling WangJen-Ho ChenJiin-Chyr HsuHsuan-Hung LinWei-Sheng ChungYung-Fu Chen Source Type: research

[In Depth] MERS surges again, but pandemic jitters ease
The number of infections of the deadly Middle East respiratory syndrome virus surges again in Saudi Arabia, but scientists are less worried that the virus will cause a pandemic than they were 3 years ago. Still, many details about the virus discovered in 2012 and harbored by camels are unclear. New research suggests that many more people than previously thought may have been infected with no or little symptoms. The best way to protect people may be a camel vaccine, and experiments to test two candidate vaccines in camels have just been finished in the United States and Europe. Author: Kai Kupferschmidt (Source: Science: Current Issue)
Source: Science: Current Issue - March 20, 2015 Category: Science Authors: Kai Kupferschmidt Tags: Infectious Diseases Source Type: research

In ovo delivery of toll-like receptor 2 ligand, lipoteichoic acid induces pro-inflammatory mediators reducing post-hatch infectious laryngotracheitis virus infection
In this study, we investigated whether in ovo LTA delivery leads to the induction of antiviral responses against post-hatch infectious laryngotracheitis virus (ILTV) infection. We first delivered the LTA into embryo day (ED)18 eggs via in ovo route so that the compound is available at the respiratory mucosa. Then the LTA treated and control ED18 eggs were allowed to hatch and the hatched chicken was infected with ILTV intratracheally on the day of hatch. We found that in ovo delivered LTA reduces ILTV infection post-hatch. We also found that in ovo delivery of LTA significantly increases mRNA expression of pro-inflammatory...
Source: Veterinary Immunology and Immunopathology - March 20, 2015 Category: Veterinary Research Source Type: research

A comparative study of the local cytokine response in the lungs of pigs experimentally infected with different PRRSV-1 strains: Upregulation of IL-1α in highly pathogenic strain induced lesions
In conclusion, the HP-PRRSV SU1-bel strain replicated more efficiently in the lung of infected animals and induced a higher expression of IL-1α than the other PRRSV-1-infected groups, which may have played a key role in the onset of the clinical signs and interstitial pneumonia. (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - March 20, 2015 Category: Veterinary Research Source Type: research

Acute phase cytokines, TAC1, and toll-like receptor4 mRNA expression and health associated with group size in veal calves
In conclusion, the number of veal calves in a group, given the same space during the finishing period did not alter IL-1Ra, TNF-α, and TLR4 mRNA expression. However, housing of calves in groups of 8 was associated with greater expression of IL-1β and TAC1 mRNA in peripheral blood leukocytes, and coughing during the first 2 months after grouping. Therefore, housing of veal calves in larger groups may lead to greater susceptibility to respiratory disease and stress. (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - March 20, 2015 Category: Veterinary Research Source Type: research

Myasthenia Gravis Presenting as Persistent Unilateral Ptosis with Facial Droop
We describe an unusual case of MG presenting with an acute onset of persistent unilateral ptosis and ipsilateral facial droop without diurnal variation or other fluctuation in severity. (Source: The Journal of Emergency Medicine)
Source: The Journal of Emergency Medicine - March 20, 2015 Category: Emergency Medicine Authors: Sean K. Golden, Chris J. Reiff, Chris J. Painter, Michael D. Repplinger Tags: Selected Topics: Neurological Emergencies Source Type: research

‘Curiouser and curiouser’: the role of vitamin D in the prevention of acute respiratory infection
(Source: Acta Paediatrica)
Source: Acta Paediatrica - March 20, 2015 Category: Pediatrics Authors: Adrian R. Martineau Tags: Editorial Source Type: research