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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 7.

Rapid Expansion of Human Epithelial Stem Cells Suitable for Airway Tissue Engineering.
CONCLUSIONS: Our method generates large numbers of functional airway basal epithelial cells with the efficiency demanded by clinical transplantation, suggesting its suitability for use in tracheal reconstruction. PMID: 26840431 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - February 3, 2016 Category: Respiratory Medicine Authors: Butler CR, Hynds RE, Gowers KH, Lee DD, Brown JM, Crowley C, Teixeira VH, Smith CM, Urbani L, Hamilton NJ, Thakrar RM, Booth HL, Birchall MA, De Coppi P, Giangreco A, O'Callaghan C, Janes SM Tags: Am J Respir Crit Care Med Source Type: research

Factors Associated with Functional Recovery Among Older ICU Survivors.
CONCLUSIONS: Among older adults who survived an ICU admission with increased disability, pre-ICU hearing and vision impairment were strongly associated with poor functional recovery within 6 months, whereas higher BMI and functional self-efficacy were associated with recovery. Future research is needed to evaluate whether interventions targeting these factors improve functional outcomes among older ICU survivors. PMID: 26840348 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - February 3, 2016 Category: Respiratory Medicine Authors: Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM Tags: Am J Respir Crit Care Med Source Type: research

Center Volume and Extracorporeal Membrane Oxygenation Support at Lung Transplantation in the Lung Allocation Score Era.
CONCLUSIONS: An adverse effect of ECMO at the time of lung transplantation was evident in low-volume centers, but absent in centers with experience of performing >170 lung transplants in the first 5 years of the lung allocation score era. PMID: 26840155 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - February 3, 2016 Category: Respiratory Medicine Authors: Hayes D, Tobias JD, Tumin D Tags: Am J Respir Crit Care Med Source Type: research

Chronic Hypoxia Accentuates Dysanaptic Lung Growth.
CONCLUSION: Our findings suggest that the adult lung did not increase lung volume later in life by expansion of an existing number of alveoli, but rather from increased alveolarization early in life. In addition, chronic hypoxia accentuates dysanaptic lung growth by increasing the lung parenchyma, but not the airways. PMID: 26840053 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - February 3, 2016 Category: Respiratory Medicine Authors: Llapur CJ, Martínez MR, Grassino PT, Stok A, Altieri HH, Bonilla F, Caram MM, Krowchuk NM, Kirby M, Coxson HO, Tepper RS Tags: Am J Respir Crit Care Med Source Type: research

Sociocultural Barriers to Lung Cancer Screening Among Korean Immigrant Men
This study adds new knowledge to a field where little information is available. It also lays the groundwork for developing culturally relevant lung cancer screening interventions for Korean Americans and the health care providers who serve them. (Source: Journal of Community Health)
Source: Journal of Community Health - February 3, 2016 Category: Global & Universal Source Type: research

Proton channels and renal hypertensive injury: a key piece of the Dahl salt-sensitive rat puzzle?
Abstract Hv1 is a voltage-gated proton channel highly expressed in phagocytic cells where it participates in the NADPH oxidase dependent respiratory burst. We have recently identified Hv1 as a novel renal channel, expressed in the renal medullary thick ascending limb that appears to importantly contribute to the pathogenesis of renal hypertensive injury in the Dahl salt-sensitive rat model. The purpose of this review is to describe the experimental approaches that we have undertaken to identify the source of excess reactive oxygen species production in the renal outer-medulla of Dahl salt-sensitive rats and the res...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - February 3, 2016 Category: Physiology Authors: O'Connor PM, Guha A, Stilphen CA, Sun J, Jin C Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research

Terrilactibacillus laevilacticus gen. nov., sp. nov., isolated from Thai soil.
Abstract A Gram-stain positive, catalase positive, facultative anaerobic, endospore-forming rod shaped bacterium, strain NK26-11 was isolated from soil in Thailand. This strain produced D-lactic acid from glucose homofermentatively. It grew at 20-45 °C and pH 5-8.5. The cell peptidoglycan contained meso-diaminopimelic acid. The major respiratory quinone was menaquinone 7 (MK-7). The DNA G+C content was 42.6 mol%. The major cellular fatty acids were anteiso-C15 : 0 and anteiso-C17 : 0. On the basis of 16S rRNA gene sequences analysis, the strain NK26-11T was closely related to B. solimangrovi JCM 18994T (93.89%), P...
Source: International Journal of Systematic and Evolutionary Microbiology - February 3, 2016 Category: Microbiology Authors: Prasirtsak B, Thongchul N, Tolieng V, Tanasupawat S Tags: Int J Syst Evol Microbiol Source Type: research

Aquisalinus flavus gen. nov., sp. nov., a new member of the family Parvularculaceae isolated from a saline lake.
Abstract A Gram-staining-negative bacterium, strain D11M-2T, was isolated from a saline lake (Lake Dasugan) in Qaidam basin, Qinghai Province, China. Its taxonomic position was determined by using a polyphasic approach. Cells were non-spore-forming rods, 0.5-0.7 µm wide and 1.2-1.6 µm long, and motile by means of a single subpolar or lateral flagellum. Strain D11M-2T was strictly heterotrophic and aerobic, and catalase- and oxidase-positive. Growth was observed in the presence of 0-14.0 % (w/v) NaCl (optimum, 2.0 %), and at 10-35 °C (optimum, 30 °C) and pH 6.0-10.5 (optimum, pH 8.0). Strain D11M-2T contained Q-...
Source: International Journal of Systematic and Evolutionary Microbiology - February 3, 2016 Category: Microbiology Authors: Zhong ZP, Liu Y, Wang F, Zhou YG, Liu HC, Liu ZP Tags: Int J Syst Evol Microbiol Source Type: research

Nerve conduction studies in lower limbs of elite Nepalese football players: an insight into neural adaptations.
CONCLUSION: Increased tibial CMAP amplitude and decreased CMAP duration in players suggest excitation of more number of motor units and higher synchronicity of muscle fibers' discharge than in controls respectively. Higher amplitude can also be attributed to increase in muscle fiber size and/or efficiency of neuromuscular transmission. Increased synchronicity indirectly reflects narrow range of conduction velocity among tibial neurons. The adaptive changes in somatic nerves need more crucial research for exact identification of sites and the structures responsible. PMID: 26842865 [PubMed - as supplied by publisher] (So...
Source: Medical Physics - February 3, 2016 Category: Physics Authors: Sharma D, Paudel BH, Khadka R, Thakur D, Shah DK, Sapkota NK, Yadav RL, Yadav PK Tags: J Sports Med Phys Fitness Source Type: research

Grain Size Distribution and Health Risk Assessment of Metals in Outdoor Dust in Chengdu, Southwestern China.
Abstract A total of 27 outdoor dust samples from roads, parks, and high spots were collected and analyzed to investigate the contamination of 11 metals (Cr, Mn, Co, Ni, Cu, Zn, As, Sr, Cd, Sb, and Pb) in Chengdu, China. The results showed that the samples from the high spots exhibited the highest heavy metal level compared with those from the roads and the parks, except for Ni, Cu, and Pb. The dust was classified into five grain size fractions. The mean loads of each grain size fraction of 11 determined metals displayed similar distribution, and the contribution of median size (63-125, 125-250, 250-500 μm) fracti...
Source: Archives of Environmental Contamination and Toxicology - February 3, 2016 Category: Environmental Health Authors: Chen M, Pi L, Luo Y, Geng M, Hu W, Li Z, Su S, Gan Z, Ding S Tags: Arch Environ Contam Toxicol Source Type: research

Veno‐Venous Extracorporeal Membrane Oxygenation (V V ECMO): Indications, Preprocedural Considerations, and Technique
We describe the indications, technical aspects, and outcomes of placing V V ECMO in adults using a dual‐lumen, single‐cannula catheter. (Source: Journal of Cardiac Surgery)
Source: Journal of Cardiac Surgery - February 3, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Aisha Shaheen, Daizo Tanaka, Nicholas C. Cavarocchi, Hitoshi Hirose Tags: Surgical Technique Source Type: research

N-acetylcysteine in COPD: why, how, and when?
Abstract Oxidants have long been recognized to have an important role in the pathogenesis of COPD, and in this cigarette smoke has a strong responsibility, because it generates a conspicuous amount of oxidant radicals able to modify the structure of the respiratory tract and to enhance several mechanisms that sustain lung inflammation in COPD. In fact, oxidative stress is highly increased in COPD and natural antioxidant capacities, mainly afforded by reduced glutathione, are often overcome. Thus an exogenous supplementation of antioxidant compounds is mandatory to at least partially counteract the oxidative stres...
Source: Multidisciplinary Respiratory Medicine - February 3, 2016 Category: Respiratory Medicine Source Type: research

Chronic obstructive pulmonary disease with Eosinophilia, an Emerging Phenotype?
PMID: 26852358 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - February 3, 2016 Category: Respiratory Medicine Authors: Baloira Villar A, Pallarés Sanmartín A Tags: Arch Bronconeumol Source Type: research

Blood eosinophils and outcomes in severe hospitalised exacerbations of COPD.
CONCLUSIONS: Patients presenting to hospital with a severe eosinophilic exacerbation of COPD have a shorter length of stay. These exacerbations are usually not associated with an elevated CRP, suggesting that better treatment stratification of exacerbations can be utilised. PMID: 26851799 [PubMed - as supplied by publisher] (Source: Chest)
Source: Chest - February 3, 2016 Category: Respiratory Medicine Authors: Bafadhel M, Greening NJ, Harvey-Dunstan TC, Williams JE, Morgan MD, Brightling CE, Hussain SF, Pavord ID, Singh SJ, Steiner MC Tags: Chest Source Type: research

A novel epigenetic signature for early diagnosis in lung cancer.
CONCLUSION: Minimally-invasive epigenetic biomarkers have emerged as promising tools for cancer diagnosis. The herein obtained epigenetic model in combination with current diagnostic protocols may improve early diagnosis and outcome of lung cancer patients. PMID: 26842235 [PubMed - as supplied by publisher] (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - February 3, 2016 Category: Cancer & Oncology Authors: Diaz-Lagares A, Mendez-Gonzalez J, Hervas D, Saigi M, Pajares MJ, Garcia D, Crujeiras AB, Pio R, Montuenga LM, Zulueta J, Nadal E, Rosell A, Esteller M, Sandoval Del Amor J Tags: Clin Cancer Res Source Type: research

Long-term trends in cardiovascular disease mortality and association with respiratory disease
Research Articles A. J. MERCER, Epidemiology & Infection, Volume 144 Issue 04, pp 777-786Abstract (Source: Epidemiology and Infection)
Source: Epidemiology and Infection - February 2, 2016 Category: Epidemiology Source Type: research

Shelter crowding and increased incidence of acute respiratory infection in evacuees following the Great Eastern Japan Earthquake and tsunami
Research Articles T. KAWANO, Y. TSUGAWA, K. NISHIYAMA, H. MORITA, O. YAMAMURA, K. HASEGAWA, Epidemiology & Infection, Volume 144 Issue 04, pp 787-795Abstract (Source: Epidemiology and Infection)
Source: Epidemiology and Infection - February 2, 2016 Category: Epidemiology Source Type: research

RT-PCR detection of exotoxin genes expression in multidrug resistant Pseudomonas aeruginosa.
Authors: Tartor YH, El-Naenaeey EY Abstract Pseudomonas aeruginosa (PA) is an opportunistic pathogen responsible for causing a wide variety of acute and chronic infections with significant levels of morbidity and mortality. These infections are very hard to eradicate because of the expression of numerous virulence factors and the intrinsic resistance against antibiotics. Herein, this study analyzed antimicrobial susceptibility of PA isolated from broiler chickens and cattle as well as expression of five significant exotoxin genes (exoU, exoS, toxA, lasB, and phzM) and ecfX as internal control. Genomic DNA was ampli...
Source: Cellular and Molecular Biology - February 2, 2016 Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research

Nutritional practices and postnatal growth restriction in preterm newborns
Conclusion: improving nutritional practices in the NICU can reduce the growth deficit in premature infants of very low birth weight.RESUMO Objetivo: avaliar as práticas nutricionais em unidade de cuidados intensivos neonatais (UCIN) associadas a déficit de crescimento em recém-nascidos pré-termo (RNPT). Métodos: estudo retrospectivo de RNPT com peso entre 500 e 1.499 g internados em UCIN. Analisaram-se: evolução do crescimento e práticas de nutrição parenteral (NP) e enteral (NE). Resultados: dentre 184 RNPT divididos em G1 (500 a 990 g; n=63) e G2 (1.000 a 1.499 g; n=121), 169 receberam NP (G1=63; G2=106). Compa...
Source: Revista da Associacao Medica Brasileira - February 2, 2016 Category: Journals (General) Source Type: research

Efficacy and adverse events of early high-frequency oscillatory ventilation in adult burn patients with acute respiratory distress syndrome
Conclusions Early HFOV therapy is effective in improving oxygenation in burn patients with ARDS, but it failed to reduce hospital mortality. (Source: Egyptian Journal of Anaesthesia)
Source: Egyptian Journal of Anaesthesia - February 2, 2016 Category: Anesthesiology Source Type: research

Supplementation with coenzyme Q10 reduces plasma lipoprotein(a) concentrations but not other lipid indices: a systematic review and meta-analysis
In conclusion, CoQ10 supplementation, in the tested range of doses, reduces plasma Lp(a) concentrations, particularly in patients with Lp(a)≥30mg/dL. Other lipid indices were not altered by CoQ10 supplementation. Graphical abstract (Source: Pharmacological Research)
Source: Pharmacological Research - February 2, 2016 Category: Drugs & Pharmacology Source Type: research

Transfers to hospital in planned home birth in four Nordic countries – A prospective cohort study
ConclusionsOne third of all nulliparous and 8.0% of multiparous women were transferred during labor or within 72 hours of the birth. The proportion of potentially urgent transfers was 3.8%.This article is protected by copyright. All rights reserved. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 2, 2016 Category: OBGYN Authors: Ellen Blix, Merethe H. Kumle, Karen Ingversen, Anette S. Huitfeldt, Hanne K. Hegaard, Ólöf Á. Ólafsdóttir, Pål Øian, Helena Lindgren Tags: Original Research Article Source Type: research

Is there a relationship between low vitamin D and rotaviral diarrhea?
ConclusionsLow vitamin D is associated with rotaviral diarrhea. This is the first study in the literature to show this, and this result needs to be repeated in larger controlled clinical studies. (Source: Pediatrics International)
Source: Pediatrics International - February 2, 2016 Category: Pediatrics Authors: Ibrahim Hakan Bucak, Agah Bahadır Ozturk, Habip Almis, Muhammer Özgür Cevik, Mehmet Tekin, Çapan Konca, Mehmet Turgut, Mehmet Bulbul Tags: Original Article Source Type: research

Prevalence of sputum smear positive pulmonary tuberculosis at Dargai, District Malakand, Pakistan: A four year retrospective study
This study was undertaken to determine the prevalence of pulmonary tuberculosis sputum smear positive (PTB-SS+ve) among the suspected TB patients at Tehsil Head Quarter (THQ) Hospital Dargai, District Malakand Khyber Pakhtunkhwa, Pakistan. A retrospective study was designed from January 2011 to December 2014. Out of 736 registered and suspected patients of TB, (40.08%) were PTB-SS+ve, (15.63%) were PTB-SS−ve whereas the remaining cases were diagnosed with extra-pulmonary TB, hence excluded from the study. The ratio of PTB-SS+ve cases was higher in females (57.63%) compared to males (42.37%). Furthermore, in the age group...
Source: Egyptian Journal of Chest Diseases and Tuberculosis - February 2, 2016 Category: Respiratory Medicine Source Type: research

Handicap status of exclusive narghile smokers compared to exclusive cigarette smokers: A case control-study
Conclusion Chronic exclusive narghile-use is less detrimental to PA and QOL than chronic exclusive cigarette smoking. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - February 2, 2016 Category: Respiratory Medicine Source Type: research

Interactive effects of hypoxia, carbon monoxide and acute lung injury on oxygen transport and aerobic capacity
This study determined how breathing hypoxic gas, reducing circulatory capacitance for O2 by breathing CO, and impairing pulmonary gas exchange by acutely injuring the lungs interact to limit cardiopulmonary O2 delivery, O2 extraction and maximal aerobic capacity (VO2max). Five goats ran on a treadmill at VO2max following oleic-acid induced acute lung injury that impaired pulmonary gas exchange, after partial recovery or with no acute lung injury. Goats breathed normoxic or hypoxic inspired gas fractions (FIO2 0.21 or 0.12) with and without small amounts of CO to maintain carboxyhemoglobin fractions (FHbCO) of 0.02 or 0.30....
Source: Respiratory Physiology and Neurobiology - February 2, 2016 Category: Respiratory Medicine Source Type: research

Blockade of dorsolateral pontine 5HT1A receptors destabilizes the respiratory rhythm in C57BL6/J wild-type mice.
Publication date: Available online 1 February 2016 Source:Respiratory Physiology & Neurobiology Author(s): RR Dhingra, M Dutschmann, TE Dick The neurotransmitter serotonin (5HT) acting via 5HT1a receptors (5HT1aR) is a potent determinant of respiratory rhythm variability. Here, we address the 5HT1aR-dependent control of respiratory rhythm variability in C57BL6/J mice. Using the in situ perfused preparation, we compared the effects of systemic versus focal blockade of 5HT1aRs. Blocking 5HT1aRs in the Kölliker-Fuse nucleus (KFn) increased the occurrence of spontaneous apneas and accounted for the systemic effec...
Source: Respiratory Physiology and Neurobiology - February 2, 2016 Category: Respiratory Medicine Source Type: research

Sequential gas delivery provides precise control of alveolar gas exchange
Publication date: Available online 1 February 2016 Source:Respiratory Physiology & Neurobiology Author(s): Joseph A. Fisher, Steve Iscoe, James Duffin Of the factors determining blood gases, only alveolar ventilation (A) is amenable to manipulation. However, current physiology text books neither describe how breath-by-breathA can be measured, nor how it can be precisely controlled in spontaneously breathing subjects. And such control must be effected independent of minute ventilation (E) and the pattern of breathing. Control ofA requires the deliberate partition of inhaled gas between the alveoli and the anato...
Source: Respiratory Physiology and Neurobiology - February 2, 2016 Category: Respiratory Medicine Source Type: research

Diaphragmatic fatigue during inspiratory muscle loading in normoxia and hypoxia
Conclusion Progression of diaphragmatic fatigue during inspiratory muscle loading assessed by Pdi,tw differs between normoxia and normobaric hypoxia: in the former, Pdi,tw follows an exponential decay, whereas during hypoxia, Pdi,tw follows a linear decline. (Source: Respiratory Physiology and Neurobiology)
Source: Respiratory Physiology and Neurobiology - February 2, 2016 Category: Respiratory Medicine Source Type: research

Chronic pulmonary aspergillosis: help is on the way
Publication date: February 2016 Source:The Lancet Respiratory Medicine, Volume 4, Issue 2 Author(s): The Lancet Respiratory Medicine (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - February 2, 2016 Category: Respiratory Medicine Source Type: research

Of mice and men—the curious tale of β blockers in asthma
Publication date: February 2016 Source:The Lancet Respiratory Medicine, Volume 4, Issue 2 Author(s): Brian Lipworth, Sunny Jabbal (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - February 2, 2016 Category: Respiratory Medicine Source Type: research

Treatment of cystic fibrosis in low-income countries
Publication date: February 2016 Source:The Lancet Respiratory Medicine, Volume 4, Issue 2 Author(s): Malena Cohen-Cymberknoh, David Shoseyov, Oded Breuer, Mahmoud Shamali, Michael Wilschanski, Eitan Kerem (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - February 2, 2016 Category: Respiratory Medicine Source Type: research

Knowledge gaps in therapeutic and non-therapeutic research on the Middle East respiratory syndrome
Publication date: February 2016 Source:The Lancet Respiratory Medicine, Volume 4, Issue 2 Author(s): Yaseen M Arabi, Rob Fowler, Rick A Bright, Maria D Van Kerkhove, Hanan H Balkhy (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - February 2, 2016 Category: Respiratory Medicine Source Type: research

Prevalence of sleep apnoea syndrome in the middle to old age general population
Publication date: February 2016 Source:The Lancet Respiratory Medicine, Volume 4, Issue 2 Author(s): Raphael Heinzer, Helena Marti-Soler, José Haba-Rubio (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - February 2, 2016 Category: Respiratory Medicine Source Type: research