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Respiratory Medicine

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 8.

The lipidome: a new player in chronic obstructive pulmonary disease pathophysiology?
PMID: 25025348 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - July 15, 2014 Category: Respiratory Medicine Authors: Donnelly LE Tags: Am J Respir Crit Care Med Source Type: research

Inhaled Interferon: A Novel Treatment for Virus-induced Asthma?
PMID: 25025347 [PubMed - in process] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - July 15, 2014 Category: Respiratory Medicine Authors: Jackson DJ Tags: Am J Respir Crit Care Med Source Type: research

Plasticity of fimbrial genotype and serotype within populations of Bordetella pertussis: analysis by paired flow cytometry and genome sequencing.
Abstract The fimbriae of Bordetella pertussis are required for colonisation of the human respiratory tract. Two serologically distinct fimbrial subunits, Fim2 and Fim3, having been considered important vaccine components for many years, are included in the Sanofi Pasteur 5-component acellular pertussis vaccine, and the World Health Organisation recommends the inclusion of strains expressing both fimbrial serotypes in whole cell pertussis vaccines. Each of the fimbrial major subunit genes, fim2, fim3, and also fimX, has a promoter poly(C) tract upstream of its -10 box. Such monotonic DNA elements are susceptible to ...
Source: Microbiology - July 15, 2014 Category: Microbiology Authors: Vaughan TE, Pratt CB, Sealey K, Preston A, Fry NK, Gorringe AR Tags: Microbiology Source Type: research

Endotracheal intubation in the pediatric emergency department.
CONCLUSION: Intubation of children in the ED is a low-frequency, high-risk procedure. The incidence of adverse events, particularly desaturation and hypotension, is high. The incidence of difficult laryngoscopy is low. First pass success rate without desaturation or hypotension is low. Strategies to avoid desaturation and hypotension in the peri-intubation setting should be prioritized. PMID: 25039321 [PubMed - as supplied by publisher] (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - July 15, 2014 Category: Anesthesiology Authors: Long E, Sabato S, Babl FE Tags: Paediatr Anaesth Source Type: research

Hormonal, Metabolic and Cardiorespiratory Responses of Young and Adult Athletes to a Single Session of High Intensity Cycle Exercise.
This study aimed to determine the effects of a single High Intensity Interval Training (HIIT) session on salivary cortisol (SC) levels, physiological responses and performance in trained boys and men. Twenty-three boys (11.5±0.8 years) and 25 men (29.7±4.6 years) performed HIIT (four consecutive Wingate Anaerobic Tests). SC in boys and men increased after HIIT from 5.55±3.3 nmol/l to 15.13±9.7 nmol/l (+173%) and from 7.07±4.7 nmol/l to 19.19±12.7 nmol/l (+171%), respectively (p<0.01). Pre-test SC as well as post-test changes were comparable in both groups (both p<0.01). Peak blood lactate concentration was sign...
Source: Pediatric Exercise Science - July 15, 2014 Category: Pediatrics Authors: Engel F, Härtel S, Wagner MO, Strahler J, Bös K, Sperlich B Tags: Pediatr Exerc Sci Source Type: research

Vitamin D Supplementation and Upper Respiratory Tract Infections in Adolescent Swimmers: A Randomized Controlled Trial.
Abstract Observational studies identified associations between vitamin D insufficiency (serum 25(OH)D<30ng·mL1) and risk of upper respiratory infection (URI). Swimmers are highly prone to URIs, which might hinder their performance. The aim of this study was to examine if vitamin D3supplementation reduces URI burden in vitamin D-insufficient swimmers. Fifty-five competitive adolescent swimmers with vitamin D insufficiency were randomized to receive vitamin D3(2,000IU·d-1) or placebo for 12 winter weeks. A URI symptom questionnaire was completed weekly. Serum 25(OH)D concentrations were measured by radio-immunoa...
Source: Pediatric Exercise Science - July 15, 2014 Category: Pediatrics Authors: Dubnov-Raz G, Rinat B, Hemilae H, Choleva L, Cohen A, Constantini N Tags: Pediatr Exerc Sci Source Type: research

Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the drugs most commonly involved in hypersensitivity drug reactions. Such reactions can be due to the release of inflammatory mediators in the absence of specific immunologic recognition, or immunoglobulin E (IgE)- or T-cell–selective responses. The former include upper and lower airway symptoms in patients with chronic underlying respiratory disease, the exacerbation of chronic spontaneous urticaria, and the induction of cutaneous symptoms. The latter include selective responses to a single NSAID with good tolerance to strong cyclooxygenase-1 inhibitors, with a putative ...
Source: Immunology and Allergy Clinics of North America - July 14, 2014 Category: Allergy & Immunology Authors: Maria Jose Torres, Esther Barrionuevo, Marek Kowalski, Miguel Blanca Source Type: research

Effect of age and sex on warfarin dosing
Khoury G, Sheikh-Taha M (Source: International Journal of COPD)
Source: International Journal of COPD - July 14, 2014 Category: Respiratory Medicine Source Type: research

Barriers to the provision of smoking cessation assistance: a qualitative study among Romanian family physicians.
Conclusions:Many of the barriers described by the Romanian FPs reflected universally recognised challenges to the provision of smoking cessation advice. The context of a relatively hierarchical health-care system and limitations of time and resources exacerbated many of the problems and created new barriers that will need to be addressed if Romania is to achieve the aims of its National Programme Against Tobacco Consumption. PMID: 25010432 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - July 14, 2014 Category: Primary Care Authors: Panaitescu C, Moffat MA, Williams S, Pinnock H, Boros M, Oana CS, Alexiu S, Tsiligianni I Tags: NPJ Prim Care Respir Med Source Type: research

Severity of rhinovirus infection in hospitalized adults is unrelated to genotype.
CONCLUSIONS: Infection with RV-A or RV-B was associated with greater severity of illness in our adult population; however, the association disappeared after controlling for confounders. PMID: 25015856 [PubMed - in process] (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - July 14, 2014 Category: Pathology Authors: McCulloch DJ, Sears MH, Jacob JT, Lyon GM, Burd EM, Caliendo AM, Hill CE, Nix WA, Oberste MS, Kraft CS Tags: Am J Clin Pathol Source Type: research

Respiratory disease and respiratory physiology: Putting lung function into perspective interstitial lung disease
Abstract The interstitial lung diseases pathologically involve the pulmonary interstitium but may also involve the airways, pleura and pulmonary circulation. They may be idiopathic, be part of other conditions, or be related to drug or environmental exposures. This review will focus on diagnostic and prognostic information provided by lung function tests in the idiopathic interstitial pneumonias, particularly idiopathic pulmonary fibrosis and non‐specific interstitial pneumonia. These disorders are characterized by small stiff lungs with impaired gas exchange. Lung function tests, particularly lung volumes and gas transf...
Source: Respirology - July 14, 2014 Category: Respiratory Medicine Authors: Norbert Berend Tags: Invited Review Series: Respiratory Disease: Using Lung Function Measurements to Greater Advantage Source Type: research

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria
We report that biguanides inhibit complex I by inhibiting ubiquinone reduction (but not competitively) and, independently, stimulate reactive oxygen species production by the complex I flavin. Biguanides also inhibit mitochondrial ATP synthase, and two of them inhibit only ATP hydrolysis, not synthesis. Thus, we identify biguanides as a new class of complex I and ATP synthase inhibitor. By comparing biguanide effects on isolated complex I and cultured cells, we distinguish three anti-diabetic and potentially anti-neoplastic biguanides (metformin, buformin and phenformin) from two anti-malarial biguanides (cycloguanil and p...
Source: BJ Energy - July 14, 2014 Category: Biochemistry Authors: H R Bridges, A J Y Jones, M N Pollak, J Hirst Tags: BJ Energy Source Type: research

Patterns of healthcare use among adolescents attending an urban general practitioner-led urgent care centre
Conclusions Adolescents aged 15–19 years are more likely to attend urgent care centres than general practice. The majority attended for conditions commonly seen in primary care including musculoskeletal conditions and injuries, and respiratory tract infections. Primary care services may need to be more responsive to needs of the older adolescent age, if their use of urgent care centres is to be reduced. (Source: Emergency Medicine Journal)
Source: Emergency Medicine Journal - July 14, 2014 Category: Emergency Medicine Authors: Gnani, S., McDonald, H., Islam, S., Ramzan, F., Davison, M., Ladbrooke, T., Majeed, A., Saxena, S. Tags: TB and other respiratory infections, Adolescent health, Child health Original article Source Type: research

Cyclin D1 Mediates Estrogen Signaling
The cyclin D1 gene encodes the regulatory subunit of a holoenyzme that phosphorylates the retinoblastoma protein (pRb) and nuclear respiratory factor (NRF1) proteins. The abundance of cyclin D1 determines estrogen-dependent gene expression in the mammary gland of mice. Using estradiol (E2) and an E2–dendrimer conjugate that is excluded from the nucleus, we demonstrate that E2 delays the DNA damage response (DDR) via an extranuclear mechanism. The E2-induced DDR required extranuclear cyclin D1, which bound ERα at the cytoplasmic membrane and augmented AKT phosphorylation (Ser473) and γH2AX foci formation. In the nucleus...
Source: Cancer Research - July 14, 2014 Category: Cancer & Oncology Authors: Li, Z., Chen, K., Jiao, X., Wang, C., Willmarth, N. E., Casimiro, M. C., Li, W., Ju, X., Kim, S. H., Lisanti, M. P., Katzenellenbogen, J. A., Pestell, R. G. Tags: Tumor and Stem Cell Biology Source Type: research

Forthcoming Meetings
(Source: Respirology)
Source: Respirology - July 14, 2014 Category: Respiratory Medicine Tags: FORTHCOMING MEETINGS Source Type: research

Journal Statistics
(Source: Respirology)
Source: Respirology - July 14, 2014 Category: Respiratory Medicine Tags: JOURNAL STATISTICS Source Type: research

Carbonic Anhydrase II Mediates Malignant Behavior of Pulmonary Neuroendocrine Tumors.
Abstract In normal lung, the predominant cytoplasmic carbonic anhydrase (CA) isozyme, CAII, is highly expressed in amine and peptide producing pulmonary neuroendocrine cells (PNEC) where its role involves CO2 sensing. Here we report robust cytoplasmic expression of CAII by immunohistochemistry in the tumor cells of different native neuroendocrine tumor (NET) types including typical and atypical carcinoids and small cell lung carcinomas, and in NET and non-NET tumor cell lines. Since, in both PNEC and related NETs the hypercapnia - induced secretion of bioactive serotonin (5-HT) is mediated by CAII, we investigated ...
Source: American Journal of Respiratory Cell and Molecular Biology - July 14, 2014 Category: Molecular Biology Authors: Zhou Y, Mokhtari RB, Pan J, Cutz E, Yeger H Tags: Am J Respir Cell Mol Biol Source Type: research

Cellular Metabolism Regulates Contact Sites between Vacuoles and Mitochondria.
Abstract Emerging evidence suggests that contact sites between different organelles form central hubs in the coordination of cellular physiology. Although recent work has emphasized the crucial role of the endoplasmic reticulum in interorganellar crosstalk, the cooperative behavior of other organelles is largely unexplored. Here, we identify a contact site named vCLAMP (vacuole and mitochondria patch) that integrates mitochondria with the lysosome-like vacuole and thus the endocytic pathway. vCLAMPs depend on the vacuolar HOPS tethering complex subunit Vps39/Vam6 and the Rab GTPase Ypt7, which also participate in m...
Source: Developmental Cell - July 14, 2014 Category: Cytology Authors: Hönscher C, Mari M, Auffarth K, Bohnert M, Griffith J, Geerts W, van der Laan M, Cabrera M, Reggiori F, Ungermann C Tags: Dev Cell Source Type: research

Performance of Masimo Rainbow Acoustic Monitoring for Tracking Changing Respiratory Rates Under Laryngeal Mask Airway General Anesthesia for Surgical Procedures in the Operating Room: A Prospective Observational Study.
CONCLUSIONS:: The data demonstrate that, under conditions of general anesthesia with a laryngeal mask airway and spontaneous ventilation, the RRa rapidly detects changes in respiratory rate, demonstrates minimal bias, and when errors in rate occur, these do not persist. The utility of this monitoring technology in detecting rate changes in unattended patients will require further study. PMID: 25025587 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 14, 2014 Category: Anesthesiology Authors: Atkins JH, Mandel JE Tags: Anesth Analg Source Type: research

A Universal Decision Support System: Addressing the Decision Making Needs of Patients, Families, and Clinicians in the Setting of Critical Illness.
Abstract In the setting of a complex critical illness, preference-sensitive decision making-choosing between two or more reasonable treatment options-can be difficult for patients, families, and clinicians alike. A common challenge to making high-quality decisions in this setting is a lack of critical information access and sharing among participants. Decision aids-brochures, web applications, and videos-are a major focus of current research because mounting evidence suggests they can improve decision making quality and enhance collaborative shared decision making. However, many decision aids have important limitat...
Source: American Journal of Respiratory and Critical Care Medicine - July 14, 2014 Category: Respiratory Medicine Authors: Cox CE, White DB, Abernethy AP Tags: Am J Respir Crit Care Med Source Type: research

Current applications of capnography in non-intubated patients.
This article reviews the most current evidence for using capnography in the non-intubated patient and summarizes the results of outcome measures reported in recent clinical trials. Capnography should be routinely used for non-intubated patients at risk for respiratory depression, in particular those receiving supplemental oxygen. PMID: 25020234 [PubMed - as supplied by publisher] (Source: Respiratory Care)
Source: Respiratory Care - July 14, 2014 Category: Respiratory Medicine Authors: Restrepo RD, Nuccio P, Spratt G, Waugh J Tags: Expert Rev Respir Med Source Type: research

Functional and pharmacological characterization of volume-regulated anion channels in human normal and cystic fibrosis bronchial and nasal epithelial cells.
This study provides the first extensive comparative functional and pharmacological analysis of VRAC currents in normal and CF airway epithelial cells and shows that VRACs are unimpaired molecularly or functionally in CF. PMID: 25034811 [PubMed - as supplied by publisher] (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - July 14, 2014 Category: Drugs & Pharmacology Authors: Stott JB, deCourcey F, Ennis M, Zholos AV Tags: Eur J Pharmacol Source Type: research

Cellular mechanism underlying Hydrogen sulfide induced mouse tracheal smooth muscle relaxation: Role of BKCa.
Abstract Recent studies have suggested that hydrogen sulfide (H2S), an important endogenous signaling gaseous molecule, participates in relaxation of smooth muscle. Nevertheless, the mechanism of this relaxation effect on respiratory system is still unclear. The present study aims to investigate the physiological function as well as cellular mechanism of H2S in tracheal smooth muscle. Application of the H2S donor, sodium hydrosulphide (NaHS) and the precursor of H2S, L-cysteine (L-Cys) induced mouse tracheal smooth muscle (TSM) relaxation in an epithelium-independent manner. The relaxation of TSM induced by NaHS wa...
Source: European Journal of Pharmacology - July 14, 2014 Category: Drugs & Pharmacology Authors: Huang J, Luo YL, Hao Y, Zhang YL, Chen PX, Xu JW, Chen MH, Zhong NS, Xu J, Zhou WL Tags: Eur J Pharmacol Source Type: research

Rapid spread of the novel respiratory syncytial virus A ON1 genotype, central Italy, 2011 to 2013.
PMID: 25011065 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - July 13, 2014 Category: Infectious Diseases Authors: Pierangeli A, Trotta D, Scagnolari C, Ferreri M, Nicolai A, Midulla F, Marinelli K, Antonelli G, Bagnarelli P Tags: Euro Surveill Source Type: research

Sensitivity of SARS/MERS CoV to Interferons and Other Drugs Based on Achievable Serum Concentrations in Humans.
Abstract A novel coronavirus (MERS-CoV) related to SARS-CoV recently emerged in the Middle East causing more than 400 deaths with a mortality rate of about 30%, much higher than SARS-CoV. Both viruses target epithelial cells in the respiratory tract, although utilizing different cellular receptors. Because of the sporadic nature of the MERS outbreak and difficulty collecting randomized, controlled clinical data, the objective of this review was to focus on published in vitro and in vivo drug sensitivity data using both cell lines and available animal models of SARS/MERS CoV infection. Determination of drug activity...
Source: Infectious Disorders Drug Targets - July 13, 2014 Category: Infectious Diseases Authors: Strayer DR, Dickey R, Carter WA Tags: Infect Disord Drug Targets Source Type: research

Vaccination of Older Adults with Dementia Against Respiratory Infections.
Abstract People with dementia are at a greater risk of complications from respiratory infections therefore can benefit from vaccinations against influenza, pneumococcal disease and pertussis. This review aimed to evaluate the uptake and impact of vaccination in older adults with dementia against respiratory infections and identify knowledge gaps. Key databases were explored, search results were assessed, relevant studies identified, and data were synthesised and summarised. Most available data suggest that older adults with dementia are less likely to receive influenza or pneumococcal vaccine while a few studies in...
Source: Infectious Disorders Drug Targets - July 13, 2014 Category: Infectious Diseases Authors: Ridda I, Dastouri F, King C, Yin JK, Tashani M, Rashid H Tags: Infect Disord Drug Targets Source Type: research

Drug therapies for reducing gastric acidity in people with cystic fibrosis.
CONCLUSIONS: Trials have shown limited evidence that agents that reduce gastric acidity are associated with improvement in gastro-intestinal symptoms and fat absorption. Currently, there is insufficient evidence to indicate whether there is an improvement in nutritional status, lung function, quality of life, or survival. Furthermore, due to the unclear risks of bias in the included trials, we are unable to make firm conclusions based on the evidence reported therein. We therefore recommend that large, multicentre, randomised controlled clinical trials are undertaken to evaluate these interventions. PMID: 25019293 [Pub...
Source: Cochrane Database of Systematic Reviews - July 13, 2014 Category: Journals (General) Authors: Ng SM, Franchini AJ Tags: Cochrane Database Syst Rev Source Type: research

SLIT: indications, follow-up, and management.
stration of SLIT in Allergic Rhinitis Abstract Specific sublingual immunotherapy (SLIT) has been proved to be a safe and effective approach in respiratory allergy. However, further research is required on aspects such as patient selection, use of optimal dosing, effects on asthma, long-term effects, and management of adverse reactions. In addition, the widely heterogeneous nature of studies on SLIT performed to date and the application of the criteria for subcutaneous immunotherapy make it difficult for the prescribing clinician to draw accurate and useful conclusions. Therefore, the QUASAR Group (QUality in the Ad...
Source: Journal of Investigational Allergology and Clinical Immunology - July 12, 2014 Category: Allergy & Immunology Authors: Dávila I, Navarro A, Domínguez-Ortega J, Alonso A, Antolín-Amérigo D, Diéguez MC, González-Mancebo E, Martíns C, Martínez C, Núñez B, Prior N, Rechel M, Rosado A, Ruiz-Hornillos J, Sansosti A, Torrecillas M, Jerez MJ, QUASAR Group, QUality Admin Tags: J Investig Allergol Clin Immunol Source Type: research

Identification of Plantago lanceolata pollen allergens using an immunoproteomic approach.
CONCLUSIONS: We detected proteins in P lanceolata pollen extracts that, to our knowledge, have not yet been studied and could worsen sensitization to this weed pollen species. The proteins identified were involved in a variety of cellular functions. By applying 2D electrophoresis and immunoblotting with a pool of 2 sera from different P lanceolata-allergic patients, we obtained a more detailed characterization of the P lanceolata allergen profile. PMID: 25011355 [PubMed - in process] (Source: Journal of Investigational Allergology and Clinical Immunology)
Source: Journal of Investigational Allergology and Clinical Immunology - July 12, 2014 Category: Allergy & Immunology Authors: Sousa R, Osório H, Duque L, Ribeiro H, Cruz A, Abreu I Tags: J Investig Allergol Clin Immunol Source Type: research

Spirometric and exhaled nitric oxide reference values in preschool children from the community of Navarra.
CONCLUSIONS: Most preschool children in our area were able to perform quality spirometry maneuvers. We obtained regression equations that allowed us to calculate the reference ranges in our population and the distribution of normal FeNO values. PMID: 25011354 [PubMed - in process] (Source: Journal of Investigational Allergology and Clinical Immunology)
Source: Journal of Investigational Allergology and Clinical Immunology - July 12, 2014 Category: Allergy & Immunology Authors: Olaguibel Rivera JM, Alvarez Puebla MJ, Arroabarren Aleman E, Cambra K, Uribe San Martin MP, De Esteban Chocarro B Tags: J Investig Allergol Clin Immunol Source Type: research

Tolerability during double-blind randomized phase I trials with the house dust mite allergy immunotherapy tablet in adults and children.
CONCLUSIONS: These trials demonstrate that doses up to 12 DU of HDM SLIT-tablet were tolerated in the selected populations, and thus are suitable for further clinical investigations in adults and children with HDM respiratory allergic disease. PMID: 25011352 [PubMed - in process] (Source: Journal of Investigational Allergology and Clinical Immunology)
Source: Journal of Investigational Allergology and Clinical Immunology - July 12, 2014 Category: Allergy & Immunology Authors: Corzo JL, Carrillo T, Pedemonte C, Plaza Martin AM, Martín Hurtado S, Dige E, Calderon MA Tags: J Investig Allergol Clin Immunol Source Type: research

Effect of age and sex on warfarin dosing
Khoury G, Sheikh-Taha M (Source: International Journal of COPD)
Source: International Journal of COPD - July 12, 2014 Category: Respiratory Medicine Source Type: research

Progress in pediatrics in 2013: choices in allergology, endocrinology, gastroenterology, hypertension, infectious diseases, neonatology, neurology, nutrition and respiratory tract illnesses
This review will provide new information related to pathophysiology and management of specific diseases that have been addressed by selected articles published in the Italian Journal of Pediatrics in 2013, focusing on allergology, endocrinology, gastroenterology, hypertension, infectious diseases, neonatology, neurology, nutrition and respiratory tract illnesses in children. Recommendations for interpretation of skin prick test to foods in atopic eczema, management of allergic conjunctivitis, hypertension and breastfeeding in women treated with antiepileptic drugs and healthy breakfast have been reported. Epidemiological s...
Source: Italian Journal of Pediatrics - July 12, 2014 Category: Pediatrics Authors: Carlo CaffarelliFrancesca SantamariaAlessandra VotteroCarlotta Povesi DascolaVirginia MirraFrancesco SperliSergio Bernasconi Source Type: research

Rescue transoesophageal echocardiography for refractory haemodynamic instability during transvenous lead extraction
Conclusion While TLE is a relatively safe procedure, life-threatening cardiovascular injuries remain a rare risk. In this study, the use of rescue TEE ruled out significant cardiovascular injuries in the majority of patients. Furthermore, rescue TEE had a substantial impact on the efficiency of determining the aetiology of refractory haemodynamic instability during TLE and thereby facilitated the timely initiation of definitive intervention. (Source: European Journal of Echocardiography)
Source: European Journal of Echocardiography - July 12, 2014 Category: Cardiology Authors: Hilberath, J. N., Burrage, P. S., Shernan, S. K., Varelmann, D. J., Wilusz, K., Fox, J. A., Eltzschig, H. K., Epstein, L. M., Nowak-Machen, M. Tags: ORIGINAL ARTICLES Source Type: research

Diagnosis and conservative management of late tracheotomy complications in chronic ventilator‐dependent patients
ConclusionIn nonsurgical candidates, insertion of a longer tube is a conservative and feasible long‐term treatment. © 2014 Wiley Periodicals, Inc. Head Neck, 2014 (Source: Head and Neck)
Source: Head and Neck - July 12, 2014 Category: ENT & OMF Authors: Ophir Ilan, Menachem Gross, Yacov Zaltzman, Ady Sasson, Esther‐Lee Marcus Tags: Original Article Source Type: research

Cleavage site and Ectodomain of HA2 sub-unit sequence of three equine influenza virus isolated in Morocco
Conclusion: The given nature virulence of three Moroccan strains, the identified and reported mutations certainly played a permissive role of infection viral process. (Source: BMC Research Notes)
Source: BMC Research Notes - July 12, 2014 Category: Research Authors: Mohamed BoukhartaFathiah ZakhamNadia TouilMehdi ElharrakMoulay Ennaji Source Type: research

Letter to the Editor in Response to: The Correlation Between Prolonged Corrected QT Interval with the Frequency of Respiratory Arrest, Endotracheal Intubation, and Mortality in Acute Methadone Overdose.
PMID: 25015895 [PubMed - as supplied by publisher] (Source: Cardiovascular Toxicology)
Source: Cardiovascular Toxicology - July 12, 2014 Category: Cardiology Authors: Park H, Collins KM, Biary R, Su M Tags: Cardiovasc Toxicol Source Type: research

Palatal surface and volume in mouth-breathing subjects evaluated with three-dimensional analysis of digital dental casts-a controlled study.
CONCLUSIONS: Subjects with prolonged mouth breathing showed a significant reduction of the palatal surface area and volume leading to a different development of the palatal morphology when compared with subjects with normal breathing pattern. PMID: 25016579 [PubMed - as supplied by publisher] (Source: European Journal of Orthodontics)
Source: European Journal of Orthodontics - July 12, 2014 Category: Dentistry Authors: Lione R, Franchi L, Huanca Ghislanzoni LT, Primozic J, Buongiorno M, Cozza P Tags: Eur J Orthod Source Type: research

Regional distribution of lung compliance by image analysis of computed tomograms.
Abstract Computed tomography (CT) can yield quantitative information about volume distribution in the lung. By combining information provided by CT and respiratory mechanics, this study aims at quantifying regional lung compliance (CL) and its distribution and homogeneity in mechanically ventilated pigs. The animals underwent inspiratory hold maneuvers at 12 lung volumes with simultaneous CT exposure at two end-expiratory pressure levels and before and after acute lung injury (ALI) by oleic acid administration. CL and the sum of positive voxel compliances from CT were linearly correlated; negative compliance areas ...
Source: Respiratory Care - July 12, 2014 Category: Respiratory Medicine Authors: Perchiazzi G, Rylander C, Derosa S, Pellegrini M, Pitagora L, Polieri D, Vena A, Tannoia A, Fiore T, Hedenstierna G Tags: Respir Physiol Neurobiol Source Type: research

Raine syndrome: An overview.
We present here a review of the pertinent literature in clinical manifestations, molecular background, diagnosis and management. PMID: 25019372 [PubMed - as supplied by publisher] (Source: European Journal of Medical Genetics)
Source: European Journal of Medical Genetics - July 12, 2014 Category: Genetics & Stem Cells Authors: Faundes V, Taucher SC, Gonzalez-Hormazabal P, Chandler K, Crosby A, Chioza B Tags: Eur J Med Genet Source Type: research

Simultaneous typing of nine avian respiratory pathogens using a novel GeXP analyzer-based multiplex PCR Assay.
Abstract A new, rapid, and high-throughput GenomeLab Gene Expression Profiler (GeXP) Analyzer-Based multiplex PCR method was developed for simultaneous detection and differentiation of nine avian respiratory pathogens The respiratory pathogens included in this study were avian influenza subtypes H5, H7, and H9, infectious bronchitis virus (IBV), Newcastle disease virus (NDV), infectious laryngotracheitis virus (ILTV), Mycoplasma gallisepticum (MG), Mycoplasma synoviae (MS) and Haemophilus paragallinarum (HPG). Ten pairs of primers were designed using conserved and specific sequence genes of AIV subtypes and respira...
Source: Journal of Virological Methods - July 12, 2014 Category: Virology Authors: Xie Z, Luo S, Xie L, Liu J, Pang Y, Deng X, Xie Z, Fan Q, Khan MI Tags: J Virol Methods Source Type: research

Immune Response to Fc Tagged GP5 Glycoproteins of Porcine Reproductive and Respiratory Syndrome Virus
Viral Immunology , Vol. 0, No. 0. (Source: Viral Immunology)
Source: Viral Immunology - July 11, 2014 Category: Allergy & Immunology Tags: article Source Type: research

Analyzing support of postnatal transition in term infants after c-section
Conclusions: The study provides data for an internal quality improvement program and supports the benefit of using routine video recording of DR-management. Furthermore, data can be used for benchmarking with current practice in other centers. (Source: BMC Pregnancy and Childbirth - Latest articles)
Source: BMC Pregnancy and Childbirth - Latest articles - July 11, 2014 Category: OBGYN Authors: Dimitrios KonstantelosSascha IfflaenderJürgen DingerWolfram BurkhardtMario Rüdiger Source Type: research

Nine cases of unintentional rapid infusion of lipid emulsion in children: root cause analysis and changes to practice
Conclusion A multidisciplinary review of the contributory factors involved in critical incidents is a useful tool to identify key areas of weakness in any system.1 Similar incidents of rapid infusion of lipid emulsions have been reported previously, including incidents involving the amino acids and lipids being administered at "switched" rates.2 3 Fat overload syndrome is a potential consequence of rapid lipid infusion and may have serious consequences including respiratory failure and metabolic acidosis and spontaneous haemorrhage.4 Prevention of administration errors is paramount to prevent harm. Introduction of a revise...
Source: Archives of Disease in Childhood - July 11, 2014 Category: Pediatrics Authors: Cole, C., Robertson, S. Tags: ORAL PRESENTATIONS Source Type: research