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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 8.

Innate immunity is a key factor for the resolution of inflammation in asthma
The resolution of inflammation is an integral and natural part of the physiological response to tissue injury, infection and allergens or other noxious stimuli. Resolution is now recognised as an active process with highly regulated cellular and biochemical events. Recent discoveries have highlighted that innate inflammatory cells have bimodal effector functions during the inflammatory response, including active roles during the resolution process. Several mediators displaying potent pro-resolving actions have recently been uncovered. Lipoxin A4, the lead member of this new class of pro-resolving mediators, has anti-inflam...
Source: European Respiratory Review - February 28, 2015 Category: Respiratory Medicine Authors: Barnig, C., Levy, B. D. Tags: Asthma and allergy Series Source Type: research

Pneumonectomy subjects with acute respiratory distress syndrome: what to do
I read with interest the article on prone ventilation in acute respiratory distress syndrome (ARDS) by Guérin [1] in the European Respiratory Review. In this extensive review, the author elaborated on the rationale, evidence and limitations of the application of prone position in ARDS patients. It is understood that excellent research has been conducted on the topic of prone position ventilation in ARDS. These findings have led to the authorisation of evidence-based medicine in prone ventilation in severe ARDS. In general, every intensive care clinician has to keep abreast of current developments in ARDS pathophysio...
Source: European Respiratory Review - February 28, 2015 Category: Respiratory Medicine Authors: Unnikrishnan, R. Tags: Lung cancer, Acute lung injury and critical care Letter Source Type: research

Near-fatal haemoptysis as presentation of a giant intralobar pulmonary sequestration
A 50-year-old female with no prior respiratory disease or symptoms presented with massive haemoptysis and respiratory failure. Multidetector computed tomographic angiography demonstrated an aberrant artery supplying a lobulated mass occupying two-thirds of the right chest (fig. 1a and b). Aortography confirmed a large aberrant systemic artery originating from the supra-diaphragmatic aorta (fig. 1c), with drainage into the pulmonary veins (fig. 1d). Emergent transcatheter arterial embolisation of the feeding artery was performed (fig. 1e). (Source: European Respiratory Review)
Source: European Respiratory Review - February 28, 2015 Category: Respiratory Medicine Authors: Ferland, N., Couture, C., Provencher, S. Tags: Pulmonary vascular disease, Interstitial and orphan lung disease Images in Respiratory Medicine Source Type: research

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Treatment of lung cancer has evolved considerably over the past few years thanks to a better understanding of the molecular mechanisms involved in lung carcinogenesis, and the development of new drugs that are able to inhibit specific key signalling pathways within the cancer cell. The best illustration of this (r)evolution is the story of epidermal growth factor receptor (EGFR or HER1) inhibitors, which have become the cornerstone for the treatment of EGFR-mutated lung cancers. These drugs were initially thought to yield modest benefit in the overall population of nonsmall cell lung cancer (NSCLC) patients, but the discov...
Source: European Respiratory Review - February 28, 2015 Category: Respiratory Medicine Authors: Cortot, A. B. Tags: Book review Source Type: research

Rapid and specific detection of porcine parvovirus using real-time PCR and High Resolution Melting (HRM) analysis
Conclusions: The present study demonstrated that the established assay integrating real-time PCR and HRM is relatively cost-effective and more stable, which provides an alternative tool for rapid, simple, specific and sensitive detection of PPV. (Source: BMC Veterinary Research)
Source: BMC Veterinary Research - February 28, 2015 Category: Veterinary Research Authors: Hai-Qiong YuXian-Quan CaiZhi-Xiong LinXiang-Li LiQiao-Yun YueRong LiXing-Quan Zhu Source Type: research

The importance of microbiological testing for establishing cause of death in 42 forensic autopsies
Microorganisms have always been responsible for both high morbidity and mortality. Even today, new bacteria and viruses are discovered and old ones evolve to become a new problem, developing resistance to antibiotics or new lethal symptoms. Autopsies are important in the process of establishing cause of death [1], and though microbiological results and findings are often unspecific [2], they continue to be a valuable tool in the process of monitoring and identifying new infectious diseases [3]. Among the more recent are hanta virus pulmonary syndrome, West Nile virus, and severe acute respiratory syndrome (SARS) [4]. (Sour...
Source: Forensic Science International - February 28, 2015 Category: Forensic Medicine Authors: S. Christoffersen Source Type: research

Association of bovine respiratory disease or vaccination with serologic response in dairy heifer calves up to three months of age.
CONCLUSIONS AND CLINICAL RELEVANCE Clinical BRD and the serologic response of dairy calves were associated with initial antibody titers against BRSV and BHV1. Serologic or clinical responses to viral exposure may differ in calves with low passive immunity. PMID: 25710760 [PubMed - in process] (Source: American Journal of Veterinary Research)
Source: American Journal of Veterinary Research - February 27, 2015 Category: Veterinary Research Authors: Windeyer MC, Leslie KE, Godden SM, Hodgins DC, Lissemore KD, LeBlanc SJ Tags: Am J Vet Res Source Type: research

Differential Distributed Lag Patterns of Source-Specific Particulate Matter on Respiratory Emergency Hospitalizations
Environmental Science & TechnologyDOI: 10.1021/es505030u (Source: Environmental Science and Technology)
Source: Environmental Science and Technology - February 27, 2015 Category: Environmental Health Authors: managing.editor at est.acs.org (American Chemical Society) Source Type: research

Association between pneumococcal pneumonia and venous thromboembolism in hospitalized patients: A nationwide population‐based study
ConclusionPneumococcal pneumonia should be considered a risk factor for DVT and PE, even after the patient has recovered from the acute infection. (Source: Respirology)
Source: Respirology - February 27, 2015 Category: Respiratory Medicine Authors: Yu‐Guang Chen, Te‐Yu Lin, Wen‐Yen Huang, Cheng‐Li Lin, Ming‐Shen Dai, Chia‐Hung Kao Tags: Original Article Source Type: research

4D CT Simulation with Synchronized Contrast Injection for Liver SBRT Patients: An Innovative Approach to a Complex Problem
Stereotactic body radiation therapy (SBRT) has emerged as a promising option for the treatment of liver metastases. SBRT delivers a highly conformal dose in a small number of fractions, making it particularly sensitive to the accuracy of target volume delineation, which can be challenging due to the poor visibility of liver lesions in the absence of intravenous contrast. In order to account for respiratory motion, 4D CT simulation is utilized for planning. A typical 4D CT scan for liver SBRT takes approximately two minutes, but the injection of contrast takes only about 30 seconds and washes out quickly, making it difficul...
Source: Journal of Medical Imaging and Radiation Sciences - February 27, 2015 Category: Radiology Authors: Darby Erler, Laurent Milot, Alex Karotki, William Chu, Renee Korol, Joelle Helou, Hans Chung Tags: Technical and Clinical Inquiry Source Type: research

[Perspectives] The library card
There was a library card and a pre-paid cell phone. The library card had a woman's name listed on it. The phone revealed the patient's final actions: he had called 911 twice. The rest of the details we knew from the emergency medical services report. They had found the patient gasping for air. He seemed to be having an allergic reaction so they gave him epinephrine and steroids. His respiratory distress worsened and they tried to intubate him, but were unsuccessful. He had been without a pulse for about 10 minutes when they did an emergency cricothyrotomy to access his airway. (Source: LANCET)
Source: LANCET - February 27, 2015 Category: Journals (General) Authors: Grace Farris Tags: Perspectives Source Type: research

A Case of Cryptococcus gattii in Western Florida: An Aggressive Pathogen in an Immunocompetent Host
Conclusions: This is a virulent VGI strain of C. gattii, causing infection in an immunocompetent host in Western Florida with no recent travel history. Here, we discuss clinical, laboratory, diagnostic, and pathologic findings of the clinical presentation and its delayed diagnostic appearance in a nonendemic area. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - February 27, 2015 Category: Infectious Diseases Tags: Case Reports Source Type: research

Causes, Features, and Outcomes of Drug-Induced Liver Injury in 69 Children from China.
Conclusions: Most cases of DILI in children are caused by antibiotics or CHM used to treat respiratory infection and present with hepatocellular injury. Compared with WM, CHM is more likely to cause severe liver injury, but liver injury caused by CHM is curable. PMID: 25717050 [PubMed - as supplied by publisher] (Source: Gut and Liver)
Source: Gut and Liver - February 27, 2015 Category: Gastroenterology Tags: Gut Liver Source Type: research

Infections in Infants Fed Formula Supplemented With Bovine Milk Fat Globule Membranes
Objectives: Observational studies have shown that even in high-income countries formula-fed infants have a higher incidence of acute otitis media (AOM), and gastrointestinal and respiratory tract infections during the first year of life compared with breast-fed infants. We hypothesized that components of the milk fat globule membrane (MFGM) may be responsible for some of these differences and that supplementation with bovine MFGM would decrease the infectious morbidity in formula-fed infants. Methods: In a double-blind randomized controlled trial, 160 formula-fed infants received experimental formula (EF) supplemented with...
Source: Journal of Pediatric Gastroenterology and Nutrition - February 27, 2015 Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research

Bedroom air quality and vacuuming frequency are associated with repeat child asthma hospital admissions
Journal of Asthma, Ahead of Print. (Source: Journal of Asthma)
Source: Journal of Asthma - February 27, 2015 Category: Respiratory Medicine Tags: article Source Type: research

Limitation of the therapeutic effort: ethical and legal justification for withholding and/or withdrawing life sustaining treatments.
Abstract Withholding and withdrawing a treatment already established are two forms of limitation of the therapeutic effort (LTE). The question of undergoing or not undergoing lifesaving medical treatments is not restricted to a specific health care context, as it refers to a variety of treatments, and it does not concern a restricted group of diseases. LTE has become part of the options compatible with the good clinical practice, in accordance with a deep change in modern medicine's 'mission' along with the increased importance attributed to the patient's general, personal condition, and to the quality of his/her l...
Source: Respiratory Care - February 27, 2015 Category: Respiratory Medicine Authors: Borsellino P Tags: Multidiscip Respir Med Source Type: research

Early treatment in preschool children: an evidence-based approach
Purpose of review: Wheezing is a common symptom in early childhood but only some of these children will experience continued wheezing symptoms in later childhood making the diagnosis and treatment of these children challenging. This review covers recent findings regarding the epidemiology, diagnosis, evaluation, and treatment of preschool-aged children with asthma. Recent findings: Key characteristics that distinguish the childhood asthma-predictive phenotype include male sex, history of wheezing with lower respiratory tract infections, history of parental asthma, history of atopic dermatitis, eosinophilia, early sensitiza...
Source: Current Opinion in Allergy and Clinical Immunology - February 27, 2015 Category: Allergy & Immunology Tags: PEDIATRIC ASTHMA AND DEVELOPMENT OF ATOPY: Edited by Carlos E. Baena-Cagnani and Leonard B. Bacharier Source Type: research

Longitudinal assessment of lung function decline in the occupational setting
Purpose of review: Spirometry is performed in the work setting as part of medical surveillance of workers with potentially respiratory hazardous work exposures, to identify early disease and evaluate the effectiveness of preventive interventions. However, many clinicians are not familiar with workplace medical surveillance and how to evaluate longitudinal spirometry over time. Recent findings: A recent American Thoracic Society technical standards report addressed issues related to performing spirometry in the work setting, including the interpretation of longitudinal lung function. Important considerations in assessing lo...
Source: Current Opinion in Allergy and Clinical Immunology - February 27, 2015 Category: Allergy & Immunology Tags: OCCUPATIONAL DISEASE: Edited by Susan M. Tarlo and Piero Maestrelli Source Type: research

Farm animal models of organic dust exposure and toxicity: insights and implications for respiratory health
This article reviews literature regarding constituents of farm animal production facility dusts, animal responses to production building and organic dust exposure, and the effect of chronic inhalation exposure on pulmonary oxidative stress and inflammation. Recent findings: Porcine models of production facility and organic dust exposures reveal striking similarities to observations of human cells, tissues, and clinical data. Oxidative stress plays a key role in mediating respiratory diseases in animals and humans, and enhancement of antioxidant levels through nutritional supplements can improve respiratory health. Summary:...
Source: Current Opinion in Allergy and Clinical Immunology - February 27, 2015 Category: Allergy & Immunology Tags: OCCUPATIONAL DISEASE: Edited by Susan M. Tarlo and Piero Maestrelli Source Type: research

Occupational diseases in individuals exposed to metal working fluids
Purpose of review: To examine the current occurrence of respiratory and skin disease in workers who do metal machining with metal working fluids (MWFs), a common work process in manufacturing. Recent findings: A summary of the 27 recognized outbreaks of respiratory disease in workers exposed to MWFs was published. New studies have identified irritative symptoms among workers with low-level exposures. There were review articles discussing the content, measurement and control of microbial agents in MWFs. Summary: The occurrence of work-related asthma and hypersensitivity pneumonitis appears to have diminished in the last 10 ...
Source: Current Opinion in Allergy and Clinical Immunology - February 27, 2015 Category: Allergy & Immunology Tags: OCCUPATIONAL DISEASE: Edited by Susan M. Tarlo and Piero Maestrelli Source Type: research

Usefulness of Noninvasive Methods for the Study of Bronchial Inflammation in the Control of Patients with Asthma
In conclusion, since asthma is an inflammatory disease, it seems appropriate to try to control it through the study of airway inflammation using noninvasive methods. In this regard, the analysis of induced sputum cells has proved very useful, although the clinical implementation of this technique seems difficult. Other techniques such as temperature measurement, the analysis of FeNO, the analysis of the VOCs in exhaled breath, or the study of certain biomarkers in EBC require further study in order to determine their clinical applicability.Int Arch Allergy Immunol 2015;166:1-12 (Source: International Archives of Allergy and Immunology)
Source: International Archives of Allergy and Immunology - February 27, 2015 Category: Allergy & Immunology Source Type: research

Comparative changes in tissue oxygenation between laparoscopic and open cholecystectomy.
CONCLUSIONS: On AS2, the greater increase in OC-((A-a)DO2) associated with Oct in vol% and SaO2% findings also in OC group suggest that LC might be associated with lower risk for impaired tissue oxygenation. PMID: 25699119 [PubMed] (Source: Clin Med Res)
Source: Clin Med Res - February 27, 2015 Category: Research Authors: Bablekos GD, Michaelides SA, Analitis A, Lymperi MH, Charalabopoulos KA Tags: J Clin Med Res Source Type: research

Conjugated Linoleic Acid (CLA) Stimulates Mitochondrial Biogenesis Signaling by the Upregulation of PPARγ Coactivator 1α (PGC-1α) in C2C12 Cells
Abstract Along with its effect on body fat reduction, dietary conjugated linoleic acid (CLA) has been reported to improve physical activity and endurance capacity in mice. It has been suggested these effects may in part be due to physiological changes in skeletal muscle, however, the mode of action is not completely understood. Thus, the purpose of this study was to determine the relevant mechanisms of CLA isomers for mitochondrial biogenesis, one of the most important adaptive responses in skeletal muscle. Both cis-9,trans-11 (c9,t11) and trans-10,cis-12 (t10,c12) CLA isomers increased the expression of peroxisom...
Source: Lipids - February 27, 2015 Category: Lipidology Source Type: research

Is There a Role for Invasive Hemodynamic Monitoring in Acute Heart Failure Management?
Abstract The place of invasive hemodynamic monitoring in patients with acute heart failure is still debated, even though frequently used. Invasive techniques, which include the pulmonary artery catheter and transpulmonary thermodilution, provide important information on cardiac output and intravascular pressures or volume. These techniques should be used in combination with echocardiography and allow nurse-driven semicontinuous hemodynamic monitoring. These techniques are useful not only in the diagnosis of circulatory or respiratory failure but also for the evaluation of the effects of therapies. Admittedly, larg...
Source: Current Heart Failure Reports - February 27, 2015 Category: Cardiology Source Type: research

Lung function following very preterm birth in the era of ‘new’ bronchopulmonary dysplasia
Abstract One of the most significant complications of preterm birth is bronchopulmonary dysplasia (BPD). The pathophysiology of BPD has changed in recent years as advances in neonatal care have led to increased survival of smaller, more preterm, infants who display alterations to alveolar and pulmonary microvascular development. It is becoming clear that infants with ‘new’ BPD experience lung disease that persists into later childhood, however, the oldest of these children are just now entering young adulthood and therefore the longer term pulmonary implications remain unknown. The role of lung function testing in the ...
Source: Respirology - February 27, 2015 Category: Respiratory Medicine Authors: Shannon J. Simpson, Graham L. Hall, Andrew C. Wilson Tags: Invited Review Series: Respiratory Disease: Using Lung Function Measurements to Greater Advantage Source Type: research

Physical activity in patients with idiopathic pulmonary fibrosis
ConclusionsThe modified MRC scale, 6MWT distance, extent of fibrosis on HRCT and serum KL‐6 levels are strongly associated with physical activity. (Source: Respirology)
Source: Respirology - February 27, 2015 Category: Respiratory Medicine Authors: Masayuki Nakayama, Masashi Bando, Koji Araki, Toshie Sekine, Fumio Kurosaki, Tetsuro Sawata, Shoko Nakazawa, Naoko Mato, Hideaki Yamasawa, Yukihiko Sugiyama Tags: Original Article Source Type: research

Endotracheal tube biofilm translocation in the lateral Trendelenburg position
Conclusions: Our findings imply that during the course of invasive MV up to 72 hour, an ETT P.aeruginosa biofilm hastily colonizes the respiratory tract. Yet, the LTP compartmentalizes colonization and infection within the proximal airways and VAP never develops. (Source: Critical Care)
Source: Critical Care - February 27, 2015 Category: Intensive Care Authors: Gianluigi BassiLaia Fernandez-BaratLina SaucedoValeria GiuntaJoan MartiOtavio RanzaniEli XiolMontserrat RigolIgnasi RocaLaura MuñozNestor LuqueMariano EsperattiMaria SacoJose RamirezJordi VilaMiguel FerrerAntoni Torres Source Type: research

Modelling the risk of airborne infectious disease using exhaled air
Publication date: Available online 19 February 2015 Source:Journal of Theoretical Biology Author(s): Chacha M. Issarow , Nicola Mulder , Robin Wood In this paper we develop and demonstrate a flexible mathematical model that predicts the risk of airborne infectious diseases, such as tuberculosis under steady state and non-steady state conditions by monitoring exhaled air by infectors in a confined space. In the development of this model, we used the rebreathed air accumulation rate concept to directly determine the average volume fraction of exhaled air in a given space. From a biological point of view, exhaled air by inf...
Source: Journal of Theoretical Biology - February 27, 2015 Category: Biology Source Type: research

Effect of context on respiratory rate measurement in identifying non‐severe pneumonia in African children
ConclusionNoise and other contextual factors may cause a transient increase in respiratory rate and consequently misclassification of non‐severe pneumonia. However, this effect is less pronounced in older children than infants. Respiratory rate is a difficult sign to measure as the variation is large between and within children. More studies of the accuracy and utility of respiratory rate as a proxy for non‐severe pneumonia diagnosis in a busy clinic are needed.This article is protected by copyright. All rights reserved. (Source: Tropical Medicine and International Health)
Source: Tropical Medicine and International Health - February 27, 2015 Category: Tropical Medicine Authors: Florida Muro, George Mtove, Neema Mosha, Hannah Wangai, Nicole Harrison, Helena Hildenwall, David Schellenberg, Jim Todd, Raimos Olomi, Hugh Reyburn Tags: Original Article Source Type: research

Phosphatidylinositol inhibits respiratory syncytial virus infection [Research Articles]
Respiratory syncytial virus (RSV) infects nearly all children under age 2, and reinfection occurs throughout life, seriously impacting adults with chronic pulmonary diseases. Recent data demonstrate that the anionic pulmonary surfactant lipid phosphatidylglycerol (PG) exerts a potent antiviral effect against RSV in vitro and in vivo. Phosphatidylinositol (PI) is also an anionic pulmonary surfactant phospholipid, and we tested its antiviral activity. PI liposomes completely suppress interleukin-8 production from BEAS2B epithelial cells challenged with RSV. The presence of PI during viral challenge in vitro reduces infection...
Source: The Journal of Lipid Research - February 27, 2015 Category: Lipidology Authors: Numata, M., Kandasamy, P., Nagashima, Y., Fickes, R., Murphy, R. C., Voelker, D. R. Tags: Research Articles Source Type: research

Phosphoinositide‐dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils
In conclusion, our data illustrate a critical role for PDK1 in transducing inhibitory signals on eosinophil effector function. Thus, our results suggest that PDK1 might serve as a novel therapeutic target in diseases involving eosinophilic inflammation. (Source: European Journal of Immunology)
Source: European Journal of Immunology - February 27, 2015 Category: Allergy & Immunology Authors: Eva M. Sturm, Gerald P. Parzmair, Balázs Radnai, Robert B. Frei, Gunter J. Sturm, Astrid Hammer, Rufina Schuligoi, Irmgard Th. Lippe, Akos Heinemann Tags: Regular Article Source Type: research

Intensive care unit acquired weakness
Publication date: Available online 27 February 2015 Source:Anaesthesia & Intensive Care Medicine Author(s): Robert John , Smita Bapat Intensive care unit acquired weakness is a broad clinical term that describes an acute neuromuscular impairment that commonly affects patients during critical illness. It is prevalent in this cohort of patients, and can be further defined by electrophysiological studies and muscle biopsies. Both limb and respiratory muscles are affected in this condition, which results in a prolonged length of stay, increased mortality and long-term disability. Early mobilization of patients and th...
Source: Anaesthesia and intensive care medicine - February 27, 2015 Category: Anesthesiology Source Type: research

Sodium butyrate epigenetically modulates high‐fat diet‐induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning
Conclusions and ImplicationsNaB treatment may be an effective pharmacological approach for type 2 diabetes and obesity by inducing −1 nucleosome repositioning within nuclear‐encoded mitochondrial genes, causing skeletal muscle mitochondrial adaptations that result in more complete β‐oxidation and a lean, insulin sensitive phenotype. (Source: British Journal of Pharmacology)
Source: British Journal of Pharmacology - February 27, 2015 Category: Drugs & Pharmacology Authors: Tara M Henagan, Barbara Stefanska, Zhide Fang, Alexandra M Navard, Jianping Ye, Natalie R Lenard, Prasad P Devarshi Tags: RESEARCH PAPER Source Type: research

Angiotensin-(1-7) improves oxygenation, while reducing cellular infiltrate and fibrosis in experimental Acute Respiratory Distress Syndrome
Conclusions: Angiotensin-(1-7), decreased the severity of acute lung injury and inflammation induced by combined acid aspiration and high stretch ventilation. Furthermore, continuous infusion of Ang-(1-7) reduced lung fibrosis 2 weeks following acid aspiration injury. These results call for further research on Ang-(1-7) as possible therapy for ARDS. (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - February 27, 2015 Category: Surgery Authors: Vanessa ZambelliGiacomo BellaniRoberto BorsaFederico PozziAlice GrassiMargherita ScanzianiVittoria CastiglioniSerge MassonAlessandra DecioJohn LaffeyRoberto LatiniAntonio Pesenti Source Type: research

Detection of influenza A and B with the Alere™ i Influenza A & B: a novel isothermal nucleic acid amplification assay
ConclusionsAlere™ i Influenza A&B is a promising new rapid influenza diagnostic assay with potential point‐of‐care applications. (Source: Influenza and Other Respiratory Viruses)
Source: Influenza and Other Respiratory Viruses - February 27, 2015 Category: Virology Authors: Briony Hazelton, Timothy Gray, Jennifer Ho, V. Mala Ratnamohan, Dominic E. Dwyer, Jen Kok Tags: Original Article Source Type: research

Sleep-disordered Breathing in Neuromuscular Disease.
Abstract Sleep-disordered breathing in neuromuscular diseases is due to an exaggerated reduction in lung volumes during supine sleep, a compromised physiologic adaptation to sleep, and specific features of the diseases that may promote upper airway collapse or heart failure. The normal decrease in the rib cage contribution to the tidal volume during phasic REM sleep becomes a critical vulnerability, resulting in saw-tooth oxygen desaturation possibly representing the earliest manifestation of respiratory muscle weakness. Hypoventilation can occur in REM sleep and progress into NREM sleep, with continuous desaturati...
Source: American Journal of Respiratory and Critical Care Medicine - February 27, 2015 Category: Respiratory Medicine Authors: Aboussouan LS Tags: Am J Respir Crit Care Med Source Type: research

Blastomonas aquatica sp. nov., a bacteriochlorophyll-containing bacterium isolated from lake water on the Tibaten Plateau, China.
Abstract Yellow or orange to brown pigmented, ovoid or rod-shaped, Gram-negative staining, aerobic strains PE 4-5T and N5-10m-1 were isolated from brackish water lake Peng Co and fresh-brackish water lake Namtso on the Tibetan Plateau, China. BChl α were produced by the isolates. The predominant cellular fatty acids were C16:1, C17:1 and C18:1 unsaturated fatty acids, C17:1 ω6c (55.3%), C17:1 ω8c (13.0%) and C18:1 ω7c (10.4%) for PE 4-5T and C18:1 ω7c (54.7%) and C16:1 ω7c (18.0%) for N5-10m-1. The polar lipid profiles of strain PE 4-5T and N5-10m-1 were composed of diphosphatidylglycerol, phosphatidylcholine...
Source: International Journal of Systematic and Evolutionary Microbiology - February 27, 2015 Category: Microbiology Authors: Xiao N, Liu Y, Liu X, Gu Z, Jiao N, Liu H, Zhou Y, Shen L Tags: Int J Syst Evol Microbiol Source Type: research

Longitudinal monitoring for respiratory pathogens in broiler chickens reveals co-infection of Chlamydia psittaci and Ornithobacterium rhinotracheale.
Abstract Chlamydia psittaci (C. psittaci) is prevalent in chicken broiler production. However, the role of C. psittaci in the respiratory disease complex needs to be clarified. It was our purpose to identify the time point when a C. psittaci infection appeared on a broiler farm and to examine the presence of other respiratory pathogens at that time. We focused on the 'major' respiratory pathogens occurring in Belgian broilers namely Infectious bronchitis virus (IBV), Avian metapneumovirus (aMPV), Ornithobacterium rhinotracheale (O. rhinotracheale), Mycoplasma gallisepticum (M. gallisepticum) and Mycoplasma synoviae...
Source: Journal of Medical Microbiology - February 27, 2015 Category: Microbiology Authors: De Boeck C, Kalmar I, Dumont A, Vanrompay D Tags: J Med Microbiol Source Type: research

Acute type A aortic dissection repair with mild-to-moderate hypothermic circulatory arrest and selective cerebral perfusion.
CONCLUSION: Circulatory arrest at more than 28 °C offered sufficient cerebral and distal organ protection for acute type A aortic dissection. PMID: 25723762 [PubMed - as supplied by publisher] (Source: The Journal of Cardiovascular Surgery)
Source: The Journal of Cardiovascular Surgery - February 27, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Numata S, Tsutsumi Y, Monta O, Yamazaki S, Seo H, Yoshida S, Samura T, Ohashi H Tags: J Cardiovasc Surg (Torino) Source Type: research

Catastrophic neurological complications of emergent endotracheal intubation: report of 2 cases.
Abstract Although exceedingly rare, catastrophic neurological decline may result from endotracheal intubation of patients with preexisting cervical spine disease. The authors report on 2 cases of quadriplegia resulting from emergent endotracheal intubation in the intensive care unit. A 68-year-old man with ankylosing spondylitis became quadriplegic after emergent intubation. A new C6-7 fracturedislocation was identified, and the patient underwent emergent open reduction and C4-T2 posterior fixation and fusion. The patient remained quadriplegic and ultimately died of pneumonia 1 year later. This is the first report ...
Source: Journal of Neurosurgery.Spine - February 27, 2015 Category: Neurosurgery Authors: Oppenlander ME, Hsu FD, Bolton P, Theodore N Tags: J Neurosurg Spine Source Type: research

Target visibility enhancement for C-arm cone beam CT-fluoroscopy-guided hepatic needle placement: implementation and accuracy evaluation
Conclusion Visibility of targets in 2D fluoroscopy was enhanced to improve interactive navigation guidance for hepatic needle placement. The target matching accuracy for the C-arm cone beam CT-fluoroscopy-guided hepatic needle targeting was sufficient for clinical use. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - February 26, 2015 Category: Intensive Care Source Type: research

Increased and early lipolysis in children with long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency during fast
Abstract Children with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHAD) have a defect in the degradation of long-chain fatty acids and are at risk of hypoketotic hypoglycemia and insufficient energy production as well as accumulation of toxic fatty acid intermediates. Knowledge on substrate metabolism in children with LCHAD deficiency during fasting is limited. Treatment guidelines differ between centers, both as far as length of fasting periods and need for night feeds are concerned. To increase the understanding of fasting intolerance and improve treatment recommendations, children with LCHAD defic...
Source: Journal of Inherited Metabolic Disease - February 26, 2015 Category: Internal Medicine Source Type: research

Graded Shuttle Run Performance by Playing Positions in Elite Female Basketball
Abstract: Štrumbelj, B, Vučković, G, Jakovljević, S, Milanović, Z, James, N, and Erčulj, F. Graded shuttle run performance by playing positions in elite female basketball. J Strength Cond Res 29(3): 793–799, 2015—A graded shuttle run test was used to assess differences in physiological parameters between playing positions in elite female basketball players. Twenty-four female basketball players (8 guards, 8 forwards, and 8 centers) who played for the senior national teams of Slovenia and Serbia were tested with the 30-15 intermittent fitness test. During the shuttle run, the following physiological parameters wer...
Source: Journal of Strength and Conditioning Research - February 26, 2015 Category: Sports Medicine Tags: Original Research Source Type: research