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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 8.

Characterization of attenuation and respiratory motion artifacts and their influence on SPECT MP image evaluation using a dynamic phantom assembly with variable cardiac defects
Conclusions Attenuation and respiratory motion correction should be applied to reduce artifacts before reporting on small defects in deep breathing conditions. Artifacts due to misalignment between CT and SPECT scans do not affect defect detection in normal breathing when the LV is co-registered in SPECT and CT images prior to AC. (Source: Journal of Nuclear Cardiology)
Source: Journal of Nuclear Cardiology - February 4, 2016 Category: Nuclear Medicine Source Type: research

Alcohol Decreases Organic Dust‐Stimulated Airway Epithelial TNF‐Alpha Through a Nitric Oxide and Protein Kinase‐Mediated Inhibition of TACE
ConclusionsThese data suggest that alcohol requires a soluble cyclase‐generated cAMP‐PKA pathway that is dependent upon the action of NO to inhibit TACE and TNF‐α release. These findings support our observations that alcohol functions through a dual NO and PKA pathway in bronchial epithelial cells. Organic dust inhalation from confined animal feeding operations (CAFOs) such as the swine facility shown above, contribute to lung inflammation and chronic lung disease. Airway epithelium is a primary target for dusts in injury and repair. In this study, alcohol exposure was found to decrease normal airway inflammation t...
Source: Alcoholism: Clinical and Experimental Research - February 4, 2016 Category: Addiction Authors: Carresse L. Gerald, Debra J. Romberger, Jane M. DeVasure, Rohan Khazanchi, Tara M. Nordgren, Art J. Heires, Joseph H. Sisson, Todd A. Wyatt Tags: Original Article Source Type: research

The Challenge of Immunoglobulin-G Subclass Deficiency and Specific Polysaccharide Antibody Deficiency – a Dutch Pediatric Cohort Study
Conclusions This is the first Western-European mainly non-tertiary cohort of children with IgG-subclass deficiency and/or SPAD. The disease course is not always benign, especially in boys. Most children were reported and managed in secondary hospitals with a pediatric immunologist in the staff. To identify more patients, the awareness of these diseases among general pediatricians should increase. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - February 4, 2016 Category: Allergy & Immunology Source Type: research

A comparative study of early and late extubation following transoral odontoidectomy and posterior fixation
Conclusion: Ventilation and oxygenation in the postoperative period in patients undergoing TOO and posterior fixation are not different between the two groups. However, the duration of ICU and hospital stay was prolonged in group D. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 4, 2016 Category: Anesthesiology Authors: Manish MardaMihir Prakash PandiaGirija Prasad RathShashank Sharad KaleHarihara Dash Source Type: research

Addition of low-dose ketamine to midazolam and low-dose bupivacaine improves hemodynamics and postoperative analgesia during spinal anesthesia for cesarean section
Conclusion: Intrathecal low-dose ketamine combined with midazolam and low-dose bupivacaine stabilizes hemodynamics and prolongs postoperative analgesia without significant side-effects in parturients undergoing CS. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 4, 2016 Category: Anesthesiology Authors: Ahmed Sobhy Basuni Source Type: research

Dexmedetomidine provides optimum conditions during awake fiberoptic intubation in simulated cervical spine injury patients
Conclusions: Dexmedetomidine provides optimum sedation without compromising airway or hemodynamic instability with better patient tolerance and satisfaction for AFOI. It also preserves patient arousability for the postintubation neurological assessment. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 4, 2016 Category: Anesthesiology Authors: Pooja ChopraMadhu Bala DixitAashish DangVibhuti Gupta Source Type: research

Consensus on Allergies and Glioma
Conclusion: A substantial amount of data on the inverse association between atopic conditions and glioma has accumulated, and findings from the GICC study further strengthen the existing evidence that the relationship between atopy and glioma is unlikely to be coincidental. Impact: As the literature approaches a consensus on the impact of allergies in glioma risk, future research can begin to shift focus to what the underlying biologic mechanism behind this association may be, which could, in turn, yield new opportunities for immunotherapy or cancer prevention. Cancer Epidemiol Biomarkers Prev; 25(2); 282–90. ©2...
Source: Cancer Epidemiology Biomarkers and Prevention - February 4, 2016 Category: Cancer & Oncology Authors: Amirian, E. S., Zhou, R., Wrensch, M. R., Olson, S. H., Scheurer, M. E., Il'yasova, D., Lachance, D., Armstrong, G. N., McCoy, L. S., Lau, C. C., Claus, E. B., Barnholtz-Sloan, J. S., Schildkraut, J., Ali-Osman, F., Sadetzki, S., Johansen, C., Houlston, R Tags: Research Articles Source Type: research

Effectiveness of the human papillomavirus (types 6, 11, 16, and 18) vaccine in the treatment of children with recurrent respiratory papillomatosis
To evaluate whether the quadrivalent human papillomavirus (HPV) (types 6, 11, 16, and 18) vaccine influences the clinical course of juvenile-onset recurrent respiratory papillomatosis (RRP) when administered to a group of patients with this condition. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - February 4, 2016 Category: ENT & OMF Authors: Juliana Sato Hermann, Lily Yin Weckx, Jussimara Monteiro Nürmberger, Gildo Francisco Dos Santos Junior, Antonio Carlos Campos Pignatari, Shirley Shizue Nagata Pignatari Source Type: research

Prospective heart tracking for whole-heart magnetic resonance angiography.
CONCLUSION: Compared with a conventional diaphragm-NAV, Heart-NAV achieves similar image quality in a slightly shorter scan time and eliminates inflow artifact. Magn Reson Med, 2016. © 2016 Wiley Periodicals, Inc. PMID: 26843458 [PubMed - as supplied by publisher] (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - February 4, 2016 Category: Radiology Authors: Moghari MH, Geva T, Powell AJ Tags: Magn Reson Med Source Type: research

Allergen-induced Changes in Bone Marrow and Airway Dendritic Cells in Asthmatic Subjects.
CONCLUSION: Inhaled allergen increases DCs in bone marrow, and trafficking of DCs into the airway which is associated with the development airway inflammation in allergic asthmatics. Inhaled allergen challenge also increases expression of TSLP, but not IL-33, receptors on bone marrow DCs. PMID: 26844926 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - February 4, 2016 Category: Respiratory Medicine Authors: El-Gammal A, Oliveria JP, Howie K, Watson R, Mitchell P, Chen R, Baatjes A, Smith S, Al-Sajee D, Hawke TJ, Killian KJ, Gauvreau GM, O'Byrne PM Tags: Am J Respir Crit Care Med Source Type: research

Nursing Students as Epidemiologists: A Simulation Approach
Simulation is commonly used in nursing education to teach clinical skills. Here, we describe the development processes, implementation, and evaluation of an epidemiology simulation used in a community and public health nursing undergraduate clinical course at the University of Pennsylvania. The simulation was designed to teach students the principles and concepts of outbreak investigation and was based on the 2003 Severe Acute Respiratory Syndrome outbreak in Toronto, Canada. The simulation places students in the role of a public health nurse in the outbreak investigation team, working in groups of five to seven students t...
Source: Clinical Simulation in Nursing - February 4, 2016 Category: Nursing Authors: Harriet Okatch, Timothy Joseph Sowicz, Helen Teng, Lucille Pilling, Monica Harmon, Christine Brewer, Alison Buttenheim Tags: Featured Article Source Type: research

Multicentric randomized clinical trial to evaluate the long-term effectiveness of a motivational intervention against smoking, based on the information obtained from spirometry in primary care: the RESET study protocol
Spirometry is the recommended method of evaluating pulmonary function when respiratory disease is suspected in smokers. Nonetheless, no evidence exists of the usefulness of information obtained from this test ... (Source: BMC Family Practice)
Source: BMC Family Practice - February 4, 2016 Category: Primary Care Authors: Francisco Martin-Lujan, Antoni Santigosa-Ayala, Josep-Lluis Piñol-Moreso, Mar Sorli-Aguilar, Gemma Flores-Mateo, Jordi Bladé-Creixenti, Josep Basora-Gallisà and Rosa Sola-Alberich Source Type: research

Streptococcus pneumoniae and Haemophilus species colonization in health care workers: the launch of invasive infections?
Streptococcus pneumoniae and Haemophilus influenzae are important human pathogens. The risk of airborne and droplet-transmitted respiratory tract infections in healthcare workers (HCW)... (Source: BMC Research Notes)
Source: BMC Research Notes - February 4, 2016 Category: Research Authors: Supram Hosuru Subramanya, Sangita Thapa, Sanjiv Kumar Dwedi, Shishir Gokhale, Brijesh Sathian, Niranjan Nayak and Indira Bairy Source Type: research

A randomised controlled trial of supplemental oxygen versus medical air during exercise training in people with chronic obstructive pulmonary disease: supplemental oxygen in pulmonary rehabilitation trial (SuppORT) (Protocol)
Oxygen desaturation during exercise is common in people with chronic obstructive pulmonary disease (COPD). The aim of the study is to determine, in people with COPD who desaturate during exercise, whether supp... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - February 4, 2016 Category: Respiratory Medicine Authors: Jennifer A Alison, Zoe J McKeough, Sue C Jenkins, Anne E Holland, Kylie Hill, Norman R Morris, Regina WM Leung, Kathleen A Williamson, Lissa M Spencer, Catherine J Hill, Annemarie L Lee, Helen Seale, Nola Cecins and Christine F McDonald Source Type: research

Later emergence of acquired drug resistance and its effect on treatment outcome in patients treated with Standard Short-Course Chemotherapy for tuberculosis
The failure of current Standard Short-Course Chemotherapy (SCC) in new and previously treated cases with tuberculosis (TB) was mainly due to drug resistance development. But little is known on the characterist... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - February 4, 2016 Category: Respiratory Medicine Authors: Jingtao Gao, Yan Ma, Jian Du, Guofeng Zhu, Shouyong Tan, Yanyong Fu, Liping Ma, Lianying Zhang, Feiying Liu, Daiyu Hu, Yanling Zhang, Xiangqun Li, Liang Li and Qi Li Source Type: research

Tools of the Trade: Point-of-Care Ultrasonography as a Stethoscope
Semin Respir Crit Care Med 2016; 37: 068-087DOI: 10.1055/s-0035-1570353Since the advent of portable ultrasonography machines, many providers, including intensivists and pulmonologists, have been trained in point-of-care ultrasonography. When point-of-care ultrasonography is performed with focused clinical question and goal in mind, it serves as a valuable adjunct to physical examination and facilitates patient care and disease management. Its clinical application is now wider than that of a stethoscope in the intensive care unit where the noise level is high. In this review article, crucial ultrasonographic findings, their...
Source: Seminars in Respiratory and Critical Care Medicine - February 4, 2016 Category: Respiratory Medicine Authors: Sekiguchi, Hiroshi Source Type: research

A phase 3, multi-center, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of levofloxacin inhalation solution (APT-1026) in stable cystic fibrosis patients
For patients with cystic fibrosis (CF), the use of inhaled antibiotics has become standard of care to suppress chronic Pseudomonas airways infection. There are limited antibiotic options formulated and approved for inhaled use and antibiotic efficacies attenuate over time, making additional inhaled antibiotic classes desirable. APT-1026 (levofloxacin inhalation solution, LIS) is a fluoroquinolone in development for management of chronic P. aeruginosa airways infection in patients with CF. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - February 4, 2016 Category: Respiratory Medicine Authors: Patrick A. Flume, Donald R. VanDevanter, Elizabeth E. Morgan, Michael N. Dudley, Jeffery S. Loutit, Scott C. Bell, Eitan Kerem, Rainald Fischer, Alan R. Smyth, Shawn D. Aaron, Douglas Conrad, David E. Geller, J. Stuart Elborn Tags: Original Article Source Type: research

ROS-1 rearrangements in non-small cell lung cancer (NSCLC): a new target for a small subset of patients but a giant leap in therapeutics
Abstract ROS1 is a membrane tyrosine kinase receptor of which encoding gene has recently been found rearranged in non-small cell lung cancer (NSCLC), leading to constitutive activation of the ROS1 kinase activity. The ROS1 gene rearrangement has been described in roughly 1 % of patients with NSCLC and such rearrangement needs to be assessed by a FISH break-apart assay (CD74-ROS1) with ROS1 immunohistochemistry as a screening tool in tumor histological samples. The clinical and histological features of patients with ROS1-rearranged NCSCL include adenocarcinoma histology with TTF-1 expression, predominantly young w...
Source: Current Respiratory Care Reports - February 4, 2016 Category: Respiratory Medicine Source Type: research

New oncogenes drivers in lung cancer—new therapeutic targets
Abstract Many advances have been achieved during the last decade in the field of lung cancer molecular biology, leading to the identification of potential new oncogene drivers and new therapeutic targets. However, only two targetable biomarkers are currently approved for lung cancer treatment: EGFR activating mutations and EML4-ALK rearrangements. Adenocarcinoma is the most common type of non-small cell lung cancer and was the first to be studied. Indeed, most of lung adenocarcinoma biomarkers were identified several years ago. Nevertheless, new therapies targeting these biomarkers are still investigated. More rec...
Source: Current Respiratory Care Reports - February 4, 2016 Category: Respiratory Medicine Source Type: research

Sulphur mustard
is a powerful vesicant (blistering agent) that was used extensively in World War I and in the Iran–Iraq conflict (1984–1987). In addition to causing characteristic blistering burns to the skin, exposure can also result in severe conjunctivitis, ulcerative necrosis throughout the respiratory tract and systemic toxicity including bone marrow suppression. There is no specific therapy for sulphur mustard poisoning, but procedures such as laser debridement of established burns have been shown to increase the rate of burn resolution in animal models and can therefore be of benefit clinically. (Source: Medicine)
Source: Medicine - February 4, 2016 Category: Internal Medicine Authors: Paul Rice Tags: Chemical terrorism Source Type: research

A prospective study to assess the diagnostic performance of the Sofia Immunoassay for Influenza and RSV detection.
Influenza A and B viruses and respiratory syncytial virus (RSV) cause a contagious respiratory disease that occurs seasonally in epidemic waves during fall and winter months in temperate climate regions. RSV is the most important cause of severe respiratory tract infections in infants and young children. Influenza viruses can cause mild to severe illness. Some groups of population (elderly, young children, and people with certain health conditions) have higher risk for serious influenza complications that can result in hospitalization and death. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - February 4, 2016 Category: Virology Authors: Sara Gomez, Columbiana Prieto, Lola Folgueira Source Type: research

Healthcare Workers Emotions, Perceived Stressors and Coping Strategies During MERS-CoV Outbreak.
CONCLUSION: The MERS-CoV outbreak was a distressing time for our staff. Hospitals can enhance HCWs experiences during any future MERS-CoV outbreak by focusing on the above mentioned aspects. PMID: 26847480 [PubMed - as supplied by publisher] (Source: Clin Med Res)
Source: Clin Med Res - February 4, 2016 Category: Research Authors: Khalid I, Khalid TJ, Qabajah MR, Barnard AG, Qushmaq IA Tags: Clin Med Res Source Type: research

Factors affecting dropout in the smoking cessation outpatient clinic.
The objective of this study was to investigate the prevalence of discontinuation in the smoking cessation outpatient clinic (SCC) and to examine the features of noncompliance. We retrospectively included 1324 smokers into the study. Patients were divided into two groups, as those who discontinued (dropped out) follow-up (group 1) and those who stayed in follow-up (group 2). Of the total 1324 smokers, 540 (40.8%) patients were in group 1. The mean age, smoking pack-years, and Fagerstrom scores of group 1 were lower than group 2 (p = 0.001, p = 0.008, and p = 0.007, respectively). In addition, the choice of treatment was als...
Source: Chronic Respiratory Disease - February 4, 2016 Category: Respiratory Medicine Authors: Bahadir A, Iliaz S, Yurt S, Ortakoylu MG, Bakan ND, Yazar E Tags: Chron Respir Dis Source Type: research

Estimating the Severity and Subclinical Burden of Middle East Respiratory Syndrome Coronavirus Infection in the Kingdom of Saudi Arabia.
Abstract Not all persons infected with Middle East respiratory syndrome coronavirus (MERS-CoV) develop severe symptoms, which likely leads to an underestimation of the number of people infected and an overestimation of the severity. To estimate the number of MERS-CoV infections that have occurred in the Kingdom of Saudi Arabia, we applied a statistical model to a line list describing 721 MERS-CoV infections detected between June 7, 2012, and July 25, 2014. We estimated that 1,528 (95% confidence interval (CI): 1,327, 1,883) MERS-CoV infections occurred in this interval, which is 2.1 (95% CI: 1.8, 2.6) times the num...
Source: Am J Epidemiol - February 4, 2016 Category: Epidemiology Authors: Lessler J, Salje H, Van Kerkhove MD, Ferguson NM, Cauchemez S, Rodriquez-Barraquer I, Hakeem R, Jombart T, Aguas R, Al-Barrak A, Cummings DA, MERS-CoV Scenario and Modeling Working Group Tags: Am J Epidemiol Source Type: research

Safety of lipid emulsion in very low‐birthweight infants according to cytokine level
ConclusionsLipid emulsion treatment did not increase inflammatory cytokine levels or aggravate respiratory disorders. Lipid emulsions, if proven safe, could be used to treat VLBW infants soon after birth, which may prevent extrauterine growth restriction and improve intellectual development prognosis. (Source: Pediatrics International)
Source: Pediatrics International - February 4, 2016 Category: Pediatrics Authors: Junko Ichikawa, Go Ichikawa, Yayoi Tsuboi, Ryota Kuribayashi, Yoshiyuki Watabe, Toshimi Sairenchi, Hiroshi Suzumura, Osamu Arisaka Tags: Original Article Source Type: research

Non‐typeable Haemophilus influenzae purulent pericarditis in a child with cystic fibrosis
We describe a case of purulent pericarditis due to NTHi in a young child with CF that developed as a complication of inadequately treated bronchopneumonia. (Source: Pediatrics International)
Source: Pediatrics International - February 4, 2016 Category: Pediatrics Authors: Kevin J Downes, Kamal Abulebda, Christopher Siracusa, Ryan Moore, Mary A Staat, Sue E Poynter Tags: Patient Report Source Type: research

Is plasticity within the retrotrapezoid nucleus responsible for the recovery of the PCO2 set-point after carotid body denervation in rats?
In conclusion, RTN regulates FR and VE in a pH-dependent manner after CBD, consistent with its postulated CCR function. RTN inhibition produces a more sustained hypopnea after CBD than before but this change may simply result from the loss of the fast feedback action of the CBs. This article is protected by copyright. All rights reserved. PMID: 26842799 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - February 4, 2016 Category: Physiology Authors: Basting TM, Abe C, Viar KE, Stornetta RL, Guyenet PG Tags: J Physiol Source Type: research

Reduced Mitochondrial Function in Human Huntington Disease Lymphoblasts is Not Due to Alterations in Cardiolipin Metabolism or Mitochondrial Supercomplex Assembly
We examined if altered Ptd2Gro metabolism was involved in the mitochondrial dysfunction associated with HD. Mitochondrial basal respiration, spare respiratory capacity, ATP coupling efficiency and rate of glycolysis were markedly diminished in Epstein-Barr virus transformed HD lymphoblasts compared to controls (CTRL). Mitochondrial supercomplex formation and Complex I activity within these supercomplexes did not vary between HD patients with different length of CAG repeats and appeared unaltered compared to CTRL. In contrast, in vitro Complex I enzyme activity in mitochondrial enriched samples was reduced in HD lymphoblast...
Source: Lipids - February 4, 2016 Category: Lipidology Source Type: research

Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4
Middle East respiratory syndrome coronavirus (MERS-CoV) causes life-threatening disease. Dipeptidyl peptidase 4 (DPP4) is the receptor for cell binding and entry. There is a need for small-animal models of MERS, but mice are not susceptible to MERS because murine dpp4 does not serve as a receptor. We developed transgenic mice expressing human DPP4 (hDPP4) under the control of the surfactant protein C promoter or cytokeratin 18 promoter that are susceptible to infection with MERS-CoV. Notably, mice expressing hDPP4 with the cytokeratin 18 promoter developed progressive, uniformly fatal disease following intranasal inoculati...
Source: The Journal of Infectious Diseases - February 4, 2016 Category: Infectious Diseases Authors: Li, K., Wohlford-Lenane, C., Perlman, S., Zhao, J., Jewell, A. K., Reznikov, L. R., Gibson-Corley, K. N., Meyerholz, D. K., McCray, P. B. Tags: VIRUSES Source Type: research

Global Mortality Impact of the 1957-1959 Influenza Pandemic
Conclusions. The global mortality rate of the 1957–1959 influenza pandemic was moderate relative to that of the 1918 pandemic but was approximately 10-fold greater than that of the 2009 pandemic. The impact of the pandemic on mortality was delayed in several countries, pointing to a window of opportunity for vaccination in a future pandemic. (Source: The Journal of Infectious Diseases)
Source: The Journal of Infectious Diseases - February 4, 2016 Category: Infectious Diseases Authors: Viboud, C., Simonsen, L., Fuentes, R., Flores, J., Miller, M. A., Chowell, G. Tags: VIRUSES Source Type: research

Pulmonary but Not Subcutaneous Delivery of BCG Vaccine Confers Protection to Tuberculosis-Susceptible Mice by an Interleukin 17-Dependent Mechanism
Some of the most promising novel tuberculosis vaccine strategies currently under development are based on respiratory vaccination, mimicking the natural route of infection. In this work, we have compared pulmonary and subcutaneous delivery of BCG vaccine in the tuberculosis-susceptible DBA/2 mouse strain, a model in which parenterally administered BCG vaccine does not protect against tuberculosis. Our data show that intranasally but not subcutaneously administered BCG confers robust protection against pulmonary tuberculosis challenge. In addition, our results indicate that pulmonary vaccination triggers a Mycobacterium tub...
Source: The Journal of Infectious Diseases - February 4, 2016 Category: Infectious Diseases Authors: Aguilo, N., Alvarez-Arguedas, S., Uranga, S., Marinova, D., Monzon, M., Badiola, J., Martin, C. Tags: BACTERIA Source Type: research

Differences between Men and Women in Time Trends in Lung Cancer Mortality in Spain (1980-2013).
CONCLUSIONS: Diverging trends in the prevalence of smoking could explain the increase in the rate of lung cancer-related mortality among Spanish women since the early 1990s. Public health policies should be implemented to reduce tobacco consumption in women and halt the increase in lung cancer mortality. PMID: 26858165 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - February 4, 2016 Category: Respiratory Medicine Authors: Martín-Sánchez JC, Clèries R, Lidón-Moyano C, González-de Paz L, Martínez-Sánchez JM Tags: Arch Bronconeumol Source Type: research

Life-threatening hemoptysis secondary to Rasmussen's aneurysm in an HIV patient.
PMID: 26854216 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - February 4, 2016 Category: Respiratory Medicine Authors: Jaureguizar Oriol A, Ayala Carbonero AM, Gorospe Sarasúa L Tags: Arch Bronconeumol Source Type: research

Reducing antibiotic prescriptions for respiratory tract infections in family practice: results of a cluster randomized controlled trial evaluating a multifaceted peer-group-based intervention
npj Primary Care Respiratory Medicine, Published online: 4 February 2016; doi:10.1038/npjpcrm.2015.83 (Source: npj Primary Care Respiratory Medicine)
Source: npj Primary Care Respiratory Medicine - February 4, 2016 Category: Primary Care Authors: Marcia VervloetMarianne A MeulepasJochen W L CalsMariëtta EimersLucas S van der HoekLiset van Dijk Source Type: research

TOTALL: high cost of allergic rhinitis—a national Swedish population-based questionnaire study
npj Primary Care Respiratory Medicine, Published online: 4 February 2016; doi:10.1038/npjpcrm.2015.82 (Source: npj Primary Care Respiratory Medicine)
Source: npj Primary Care Respiratory Medicine - February 4, 2016 Category: Primary Care Authors: Lars-Olaf CardellPetter OlssonMorgan AnderssonKarl-Olof WelinJohanna SvenssonGunnel Ragnarson TennvallJohan Hellgren Source Type: research

Aspirin-Exacerbated Respiratory Disease — New Prime Suspects
New England Journal of Medicine, Volume 374, Issue 5, Page 484-488, February 2016. (Source: New England Journal of Medicine)
Source: New England Journal of Medicine - February 3, 2016 Category: Internal Medicine Tags: article Source Type: research

Effect of N-Phenylanthranilic Acid Scaffold Nonsteroidal Anti-inflammatory Drugs on the Mitochondrial Permeability Transition.
Abstract Hepatotoxicity is a known side effect of nonsteroidal anti-inflammatory drugs (NSAIDs). In the present study, the effects of N-phenylanthranilic acid (NPA) scaffold NSAIDs on rat liver mitochondria were examined. Mefenamic acid (MEF, 200 µM) induced mitochondrial swelling, which was inorganic phosphate (Pi)-dependent and suppressed by cyclosporin A (CsA, 2.5 µM), similar to calcium-induced swelling. Mitochondrial swelling was also observed following the addition of 200 µM flufenamic acid (FLU), meclofenamic acid (MCL), and tolfenamic acid (TOL). Less swelling was observed with the addition of 200...
Source: Biological and Pharmaceutical Bulletin - February 3, 2016 Category: Drugs & Pharmacology Authors: Tatematsu Y, Hayashi H, Taguchi R, Fujita H, Yamamoto A, Ohkura K Tags: Biol Pharm Bull Source Type: research

[The place of inhaled corticosteroids in COPD].
CONCLUSION: Primary care physicians as well as pulmonologists should be better aware of the benefits as well as the side-effects and costs of inhaled corticosteroids. PMID: 26831345 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 3, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Between law and recommendations: What position for the struggle against tuberculosis?]
Authors: Rivollier É PMID: 26827106 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 3, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Primitive sternoclavicular septic arthritis].
CONCLUSION: Sternoclavicular infections should be evoked early in the course of sternoclavicular pain in order to avoid any locoregional complications and mostly mediastinitis. PMID: 26827105 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 3, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Chronic obstructive pulmonary disease (COPD) and the interior environment].
CONCLUSION: Further studies are necessary to evaluate their role in COPD and explore the underlying mechanisms. Irritative phenomena could be involved. PMID: 26827104 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 3, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Chronic alveolar condensations with erythematous cutaneous lesions].
Authors: Darmon A, Carlos Molano L, Abramovici O, Duval-Modeste AB, Louvel JP, Piton N, Muir JF, Cuvelier A PMID: 26827103 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 3, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[A rare cause of haemorrhagic pleurisy: Dissection of the aorta].
CONCLUSIONS: Aortic dissection remains among the diagnoses to consider in the case of a haemorrhagic pleural effusion despite absence of the usual suggestive symptoms. PMID: 26827102 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 3, 2016 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Diffuse Pulmonary Ossification].
Authors: Avsar K, Behr J, Morresi-Hauf A Abstract Diffuse pulmonary ossification (DPO) represents an uncommon condition usually associated with different underlying pulmonary and extrapulmonary diseases. In this work, we discuss eleven patients of our clinic with the diagnosis of a diffuse pulmonary ossification. We focus on histological changes in the surrounding lung tissue. Clinical and radiological findings were analysed. The aim of the study is to collect data for a better understanding of this condition, especially in association with interstitial lung disease.Three patients with interstitial lung disease had...
Source: Pneumologie - February 3, 2016 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

Long‐Term Extracorporeal Membrane Oxygenation as Bridging Strategies to Lung Transplantation in Rapidly Devastating Isolated Langerhans Cell Histiocytosis
Isolated pulmonary involvement in pediatric Langerhans cell histiocytosis (LCH) is extremely rare. While the multisystem‐LCH course varies from spontaneous remission to rapid deterioration with lethal outcome, single system involvement is generally associated with favorable prognosis. A child with isolated pulmonary LCH had an extremely rapid progression leading to respiratory failure, despite treatment with prednisone and vinblastine. Since lung hyperinflation and cystic degeneration contraindicated conventional mechanical ventilation, extracorporeal membrane oxygenation (ECMO) was chosen for 50 days as a bridge to lung...
Source: Pediatric Blood and Cancer - February 3, 2016 Category: Cancer & Oncology Authors: Oliviero Sacco, Andrea Moscatelli, Massimo Conte, Chiara Grasso, Gian Michele Magnano, Angela Rita Sementa, Alberto Martelli, Giovanni A. Rossi Tags: BRIEF REPORT Source Type: research