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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 8.

Respiratory virus infections among children in South China
This study aimed to determine the prevalence and clinical characteristics of children with viral‐induced acute respiratory tract infection, in Southern China. Nasopharyngeal aspirate samples from 1,980 pediatric patients with suspected acute respiratory tract infection, and 82 samples from healthy subject controls were collected for routine examination at the Second Affiliated Hospital of Shantou University Medical College, from October 2007 to August 2011. Specimens were tested by multiplex polymerase chain reaction (mPCR). At least one or more viruses were detected from 1,087 samples (54.9%). These included laboratory ...
Source: Journal of Medical Virology - March 12, 2014 Category: Virology Authors: Xiao‐Ying Cai, Qiong Wang, Guang‐Yu Lin, Zhi‐Wei Cai, Chuang‐Xing Lin, Pai‐Zhen Chen, Xiao‐Hua Zhou, Jin‐Chun Xie, Xue‐Dong Lu Tags: Research Article Source Type: research

The author replies
(Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - March 12, 2014 Category: Respiratory Medicine Tags: Response to the Letter Source Type: research

Factors predicting mortality in newborn ventilation
ConclusionsBirth‐weight, oxygenation‐index, malondialdehyde level, inotropic support, and septicemia are independent mortality predictors of neonatal ventilation. Increase in malondialdehyde level is associated with higher mortality rate, indicating possible role of free radical injury. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - March 12, 2014 Category: Respiratory Medicine Authors: Biswanath Basu, Sunil K. Sinha, T. Basu, T.K.S. Mahapatra Tags: Original Article: Neonatal Lung Disease Source Type: research

A randomized pilot study comparing heated humidified high‐flow nasal cannulae with NIPPV for RDS
ConclusionsOur pilot study suggests that HHHFNC maybe as effective as NIPPV in preventing endotracheal ventilation in the primary treatment of RDS in premature infants (<35 weeks GA and BW >1,000 g). Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - March 12, 2014 Category: Respiratory Medicine Authors: Amir Kugelman, Arieh Riskin, Waseem Said, Irit Shoris, Frida Mor, David Bader Tags: Original Article Source Type: research

Depression, illness severity, and healthcare utilization in cystic fibrosis
Summary Cystic fibrosis (CF) is an illness associated with high healthcare utilization and healthcare costs, even when compared to other chronic illnesses. In a variety of medical populations, depression has been found to be associated with lower adherence and poorer medical outcomes. The current study is a retrospective chart review of a matched set of 40 patients with CF, half with and half without a depressive disorder diagnosis. Participants were matched on the basis of their age, gender and lung function, and compared in terms of their illness severity (lung function and weight), medical adherence, and healthcare util...
Source: Pediatric Pulmonology - March 12, 2014 Category: Respiratory Medicine Authors: Carolyn Snell, Serena Fernandes, I. Simona Bujoreanu, Georgina Garcia Tags: Original Article: Cystic Fibrosis Source Type: research

Organophosphate poisoning presenting with muscular weakness and abdominal pain- a case report
Conclusion: Organophosphate poisonings causes up to 25% mortality worldwide. A major contributing factor for that are different complications. Awareness of these complications can reduce both mortality and morbidity. Early diagnosis of complications and timely therapeutic measures can improve prognosis. (Source: BMC Research Notes)
Source: BMC Research Notes - March 12, 2014 Category: Research Authors: Fazle ChowdhuryMd BariMM AlamMd RahmanBinayak BhattacharjeeJunaid QayyumMd Mridha Source Type: research

A randomized controlled trial of a nurse-led case management programme for hospital-discharged older adults with co-morbidities.
CONCLUSION: The postdischarge interventions led by the nurse case managers on self-management of disease using the empowerment approach were able to provide effective clinical and patient outcomes for older patients having co-morbidities. PMID: 24617755 [PubMed - as supplied by publisher] (Source: Adv Data)
Source: Adv Data - March 12, 2014 Category: Epidemiology Authors: Chow SK, Wong FK Tags: J Adv Nurs Source Type: research

Adenovirus type 4 and type 7 vaccination or type 4 respiratory infection elicit minimal cross-reactive antibody to non-human adenovirus vaccine vectors.
Abstract Anti-vector immunity may limit the immunogenicity of adenovirus vector vaccines. We tested serum from individuals immunized with adenovirus types 4 and 7 (Ad4, Ad7) vaccine or naturally infected with Ad4 for their ability to neutralize a panel of E1-deleted human and chimpanzee adenoviruses (ChAd). Small, statistically significant, increases in titer were observed to ChAd63, ChAd3, human Ad35 and Ad5. Neutralizing antibodies elicited by Ad4 infection or immunization results in a small amount of adenovirus cross-reactivity. PMID: 24623627 [PubMed - as supplied by publisher] (Source: Clinical and Vaccine Immunology)
Source: Clinical and Vaccine Immunology - March 12, 2014 Category: Allergy & Immunology Authors: Paris R, Kuschner RA, Binn L, Thomas SJ, Colloca S, Nicosia A, Cortese R, Bailer RT, Sullivan N, Koup RA Tags: Clin Vaccine Immunol Source Type: research

Effect of Obstructive Respiratory Events on Blood Pressure and Renal Perfusion in a Pig Model for Sleep Apnea.
CONCLUSIONS: Repetitive obstructive respiratory events result in postapneic BP rises and renal hypoperfusion, as well as neurohumoral responses and increased protein/creatinine ratio. These changes are mainly sympathetically driven because they could be attenuated by RDN. PMID: 24622919 [PubMed - as supplied by publisher] (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - March 12, 2014 Category: Cardiology Authors: Linz D, Mahfoud F, Linz B, Hohl M, Schirmer SH, Wirth KJ, Böhm M Tags: Am J Hypertens Source Type: research

Influence of the cardiac glycoside digoxin on cardiac troponin I, acid¿base and electrolyte balance, and haematobiochemical profiles in healthy donkeys (Equus asinus)
Conclusions: It is concluded that administration of digoxin to healthy donkeys (14 μg/kg) did not result in elevations of serum cTnI concentration, signs of digoxin intoxication, ECG abnormalities and did not increase serum concentrations of blood urea nitrogen and creatinine. (Source: BMC Veterinary Research - Latest articles)
Source: BMC Veterinary Research - Latest articles - March 12, 2014 Category: Veterinary Research Authors: Mohamed TharwatFahd Al-Sobayil Source Type: research

Stüve-Wiedemann syndrome: LIFR and associated cytokines in clinical course and etiology
Stüve-Wiedemann syndrome (STWS; OMIM #610559) is a rare bent-bone dysplasia that includes radiologic bone anomalies, respiratory distress, feeding difficulties, and hyperthermic episodes. STWS usually results in infant mortality, yet some STWS patients survive into and, in some cases, beyond adolescence. STWS is caused by a mutation in the leukemia inhibitory factor receptor (LIFR) gene, which is inherited in an autosomally recessive pattern. Most LIFR mutations resulting in STWS are null mutations which cause instability of the mRNA and prevent the formation of LIFR, impairing the signaling pathway. LIFR signaling usuall...
Source: Orphanet Journal of Rare Diseases - March 12, 2014 Category: Internal Medicine Authors: Dawn MikelonisCheryl JorcykKen TawaraJulia Oxford Source Type: research

Sub regional estimates of morbidities in the English elderly population.
This study focuses on identifying the future trends and spatial concentrations of morbidities in the English elderly population. The morbidities to be estimated are: coronary heart disease; strokes; diabetes; cancer; respiratory illnesses and arthritis in the 60 year and older household residential population. The technique used is a spatial microsimulation of the elderly population of local authorities in England using data from the 2001 Census and the English Longitudinal Study of Ageing. The longitudinal nature of the microsimulated population is then used to estimate the morbidity prevalences for local authorities in 2...
Source: Health and Place - March 12, 2014 Category: Environmental Health Authors: Clark SD, Birkin M, Heppenstall A Tags: Health Place Source Type: research

Redox Proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after Doxorubicin treatment.
This study demonstrates that the level of proteins adducted by 4-hydroxy-2-nonenal (HNE), a lipid peroxidation product, is significantly increased in mouse heart mitochondria following DOX treatment. A redox proteomics method involving 2D electrophoresis followed by mass spectrometry and investigation of protein data bases identified several HNE- modified mitochondria proteins, which were verified by HNE- specific immunoprecipitation in cardiac mitochondria from the DOX- treated mice. The majority of the identified proteins are related to mitochondrial energy metabolism. These include proteins in the citric acid cycle (TCA...
Source: Free Radical Biology and Medicine - March 12, 2014 Category: Biology Authors: Zhao Y, Miriyala S, Miao L, Mitov M, Schnell D, Dhar SK, Cai J, Klein JB, Sultana R, Butterfield DA, Vore M, Batinic-Haberle I, Bondada S, St Clair DK Tags: Free Radic Biol Med Source Type: research

Genetics of cystic fibrosis: CFTR mutation classifications toward genotype-based CF therapies.
This article is part of a Directed Issue entitled: Cystic Fibrosis: From o-mics to cell biology, physiology, and therapeutic advances. PMID: 24631642 [PubMed - as supplied by publisher] (Source: The International Journal of Biochemistry and Cell Biology)
Source: The International Journal of Biochemistry and Cell Biology - March 12, 2014 Category: Biochemistry Authors: Fanen P, Wohlhuter-Haddad A, Hinzpeter A Tags: Int J Biochem Cell Biol Source Type: research

Urgent Cardiac Surgery During Pregnancy: A Continuous Challenge.
CONCLUSIONS: Urgent and emergency valve replacement in pregnant women can be achieved with good maternal morbidity and mortality; however, high incidence of fetal losses might be expected when surgery is performed at an early gestational age. PMID: 24630768 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - March 12, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Elassy SM, Elmidany AA, Elbawab HY Tags: Ann Thorac Surg Source Type: research

Operative Management of Acquired Thoracic Dystrophy in Adults After Open Pectus Excavatum Repair.
CONCLUSIONS: ATD may be associated with early childhood Ravitch repair. Adults may present with disabling symptoms related to cardiac compression and restrictive pulmonary function. Reconstruction with sternal elevation and expansion of the anterior chest subjectively improves symptoms. PMID: 24630766 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - March 12, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Jaroszewski DE, Notrica DM, McMahon LE, Hakim FA, Lackey JJ, Gruden JF, Steidley DE, Johnson KN, Mookadam F Tags: Ann Thorac Surg Source Type: research

[Extrarespiratory manifestations of Mycoplasma pneumoniae: A case report.]
Abstract Extrapulmonary manifestations of Mycoplasma pneumoniae are sometimes severe and may even be life-threatening. A 10-year-old patient was hospitalized due to a flu-like illness lasting 48h with impaired general condition, after an extended stay in Africa. There was an inflammatory syndrome associated with hyponatremia, but malaria was negative. A triple antibiotic therapy with ceftriaxone, amikacin, and josamycin was started. The progression was marked by the appearance of hypoxemia pneumoniae associated with extrarespiratory manifestations. He initially presented with acute polyradiculoneuropathy, followed ...
Source: Archives de Pediatrie - March 12, 2014 Category: Pediatrics Authors: Guillet E, Mas C, Bauvin I, Beze Beyrie P, Mansir T, Guérin B Tags: Arch Pediatr Source Type: research

Lung ultrasound in the evaluation of pleural effusion
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Can ultrasound guidance reduce the risk of pneumothorax following thoracentesis?
CONCLUSIONS: Ultrasound guidance increases the yield of thoracentesis and reduces the risk of post-procedure pneumothorax. (Chinese Clinical Trial Registry identifier: ChiCTR-TRC-12002174 [http://www.chictr.org/en/]) OBJETIVO: Dentre os procedimentos realizados à beira do leito, a toracocentese é um dos mais comumente associados a complicações iatrogênicas, particularmente pneumotórax. Foram recentemente identificados vários fatores de risco de complicações associadas à toracocentese: a inexperiência do operador, a inadequação ou inexperiência da equipe de apoio, a ausência de um protocolo padronizado e a au...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Factors related to the incorrect use of inhalers by asthma patients
CONCLUSIONS: In the sample studied, incorrect inhaler technique was associated with poor asthma control. Widowhood, use of metered dose inhalers, low socioeconomic level, and the presence of > 2 comorbidities were associated with incorrect inhaler technique. OBJETIVO: Avaliar a técnica inalatória em pacientes com asma atendidos ambulatorialmente, estabelecendo associações dessa com o grau de controle da doença. MÉTODOS: Estudo transversal envolvendo pacientes com idade > 14 anos e diagnóstico médico de asma, recrutados no Ambulatório de Asma do Hospital de Clínicas de Porto Alegre, na cidade de Porto Alegr...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Morbidity, mortality, and categorization of the risk of perioperative complications in lung cancer patients
CONCLUSIONS: Although spirometry was sufficient for risk assessment in the majority of the population studied, CPET played a key role in the identification of high-risk patients, among whom the mortality rate was seven times higher than was that observed for those at an acceptable risk of PCs. The risk factors related to PCs coincided with those reported in previous studies. OBJETIVO: Determinar as taxas de morbidade e mortalidade por categoria de risco conforme as diretrizes do American College of Chest Physicians, verificar como exames funcionais participaram dessa categorização e identificar fatores de risco para comp...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

PLATINO, a nine-year follow-up study of COPD in the city of São Paulo, Brazil: the problem of underdiagnosis
CONCLUSIONS: The underdiagnosis rate for new COPD cases was lower in the follow-up phase of the study than in the initial phase. The subjects who were not diagnosed until the end of the follow-up phase of the PLATINO study presented with the same clinical profile as did those who were not diagnosed in the initial phase. These findings underscore the need for spirometry in order to confirm the diagnosis of COPD and provide early intervention. OBJETIVO: Determinar a taxa de subdiagnóstico em novos casos de DPOC em uma amostra de pacientes após nove anos de seguimento do estudo "Projeto Latino-Americano de Investigação em...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Incidence of pulmonary embolism during COPD exacerbation
CONCLUSIONS: The prevalence of PE in patients with COPD exacerbation was higher than expected. The association between PE and COPD exacerbation should be considered, especially in patients who are immobile or obese. OBJETIVO: Visto que a embolia pulmonar (EP) e a exacerbação da DPOC têm apresentação e sintomas comuns, o diagnóstico de EP pode ser negligenciado nesses pacientes. Nosso objetivo foi determinar a prevalência de EP durante a exacerbação da DPOC e descrever os aspectos clínicos em portadores de DPOC diagnosticados com EP. MÉTODOS: Estudo prospectivo conduzido em um hospital universitário na cidade d...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

A new experimental model of cigarette smoke-induced emphysema in Wistar rats
CONCLUSIONS: The new murine model of cigarette smoke-induced emphysema and the methodology employed in the present study are effective and reproducible, representing a promising and economically viable option for use in studies investigating the pathophysiology of and therapeutic approaches to COPD. OBJETIVO: Descrever um novo modelo murino de enfisema induzido pela fumaça de cigarro. MÉTODOS: Vinte e quatro ratos Wistar foram divididos em dois grupos: o grupo fumaça de cigarro, com 12 ratos expostos à fumaça de 12 cigarros comerciais com filtro três vezes ao dia (um total de 36 cigarros por dia), sete dias por sema...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Chest compression with a higher level of pressure support ventilation: effects on secretion removal, hemodynamics, and respiratory mechanics in patients on mechanical ventilation
CONCLUSIONS: In this sample, chest compression accompanied by an increase in pressure support significantly increased the amount of secretions removed, the expiratory tidal volume, and dynamic compliance. (ClinicalTrials.gov Identifier:NCT01155648 [http://www.clinicaltrials.gov/]) OBJETIVO: Determinar a eficácia da manobra de compressão torácica, associada ao acréscimo de 10 cmH2O na pressão inspiratória basal em modo ventilatório com pressão de suporte, em comparação com a da aspiração isolada, em relação a remoção de secreções, normalização da hemodinâmica e melhora da mecânica pulmonar em pacientes...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

The burden of disease due to tuberculosis in the state of Santa Catarina, Brazil
CONCLUSIONS: In the majority of the health care macroregions of Santa Catarina, the burden of disease due to tuberculosis was concentrated in adult males, the level of that concentration varying among the various macroregions. OBJETIVO: Estimar a carga de doença por tuberculose no estado de Santa Catarina em 2009. MÉTODOS: Estudo epidemiológico de delineamento ecológico. Dados sobre a incidência e mortalidade de tuberculose foram coletados de bancos de dados específicos do Ministério da Saúde do Brasil. A carga de doença por tuberculose baseou-se no cálculo de disability-adjusted life years (DALYs, anos de vida ...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Empyema and bacteremic pneumococcal pneumonia in children under five years of age
We compared bacteremic pneumococcal pneumonia (BPP) and pneumococcal empyema (PE), in terms of clinical, radiological, and laboratory findings, in under-fives. A cross-sectional nested cohort study, involving under-fives (102 with PE and 128 with BPP), was conducted at 12 centers in Argentina, Brazil, and the Dominican Republic. Among those with PE, mean age was higher; disease duration was longer; and tachypnea, dyspnea, and high leukocyte counts were more common. Among those with BPP, fever and lethargy were more common. It seems that children with PE can be distinguished from those with BPP on the basis of clinical and ...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Assessment of ICU readmission risk with the Stability and Workload Index for Transfer score
Patient discharge from the ICU is indicated on the basis of clinical evidence and the result of strategies aimed at improving health care. Nevertheless, some patients might be discharged too early. We attempted to identify risk factors for unplanned ICU readmission, using a score for risk assessment, designated the Stability and Workload Index for Transfer (SWIFT) score. We evaluated 100 patients discharged from an ICU and found that the SWIFT score can be used as a tool for improving the assessment of ICU patients and the appropriateness of ICU discharge, thus preventing readmission.A alta da UTI é indicada com base em e...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Adalimumab-induced acute interstitial lung disease in a patient with rheumatoid arthritis
In this study, we report the first case of acute ILD secondary to the use of adalimumab in Brazil, in a patient with rheumatoid arthritis and without a history of ILD.O uso de imunobiológicos no tratamento das doenças autoimunes é cada vez mais frequente na prática médica. Terapias anti-TNF têm sido cada vez mais utilizadas nas doenças autoimunes refratárias, especialmente na artrite reumatoide, com resultados promissores. Entretanto, o uso dessas terapias está relacionado ao aumento do risco do desenvolvimento de outras doenças autoimunes. Adicionalmente, o uso de agentes anti-TNF pode determinar repercussões p...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Add-on treatment with nebulized hypertonic saline in a child with plastic bronchitis after the Glenn procedure
We present the case of an 18-month-old female patient with PB following pneumonia. At 6 months of age, the patient underwent the Glenn procedure due to functionally univentricular heart. Fiberoptic bronchoscopy revealed complete blockage of the left bronchus by mucoid casts. Pharmacotherapy consisted of glucocorticosteroids, azithromycin, and enalapril maleate. The child also received nebulized 3% NaCl solution, which proved to be beneficial. In children submitted to Fontan-type procedures, physicians must be alert for PB, which can be triggered by respiratory tract infection.A bronquite plástica (BP), embora uma causa ra...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Tiotropium use and pulmonary function in patients with constrictive bronchiolitis
We present the case of an 18-month-old female patient with PB following pneumonia. At 6 months of age, the patient underwent the Glenn procedure due to functionally univentricular heart. Fiberoptic bronchoscopy revealed complete blockage of the left bronchus by mucoid casts. Pharmacotherapy consisted of glucocorticosteroids, azithromycin, and enalapril maleate. The child also received nebulized 3% NaCl solution, which proved to be beneficial. In children submitted to Fontan-type procedures, physicians must be alert for PB, which can be triggered by respiratory tract infection.A bronquite plástica (BP), embora uma causa ra...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Interstitial pneumonia following exposure to fluorocarbon polymers
We present the case of an 18-month-old female patient with PB following pneumonia. At 6 months of age, the patient underwent the Glenn procedure due to functionally univentricular heart. Fiberoptic bronchoscopy revealed complete blockage of the left bronchus by mucoid casts. Pharmacotherapy consisted of glucocorticosteroids, azithromycin, and enalapril maleate. The child also received nebulized 3% NaCl solution, which proved to be beneficial. In children submitted to Fontan-type procedures, physicians must be alert for PB, which can be triggered by respiratory tract infection.A bronquite plástica (BP), embora uma causa ra...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Mixed pneumoconiosis due to silicates and hard metals associated with primary Sjögren's syndrome due to silica
We present the case of an 18-month-old female patient with PB following pneumonia. At 6 months of age, the patient underwent the Glenn procedure due to functionally univentricular heart. Fiberoptic bronchoscopy revealed complete blockage of the left bronchus by mucoid casts. Pharmacotherapy consisted of glucocorticosteroids, azithromycin, and enalapril maleate. The child also received nebulized 3% NaCl solution, which proved to be beneficial. In children submitted to Fontan-type procedures, physicians must be alert for PB, which can be triggered by respiratory tract infection.A bronquite plástica (BP), embora uma causa ra...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Mounier-Kuhn syndrome: a rare and often overlooked cause of bronchial dilation and recurrent respiratory tract infections
We present the case of an 18-month-old female patient with PB following pneumonia. At 6 months of age, the patient underwent the Glenn procedure due to functionally univentricular heart. Fiberoptic bronchoscopy revealed complete blockage of the left bronchus by mucoid casts. Pharmacotherapy consisted of glucocorticosteroids, azithromycin, and enalapril maleate. The child also received nebulized 3% NaCl solution, which proved to be beneficial. In children submitted to Fontan-type procedures, physicians must be alert for PB, which can be triggered by respiratory tract infection.A bronquite plástica (BP), embora uma causa ra...
Source: Jornal Brasileiro de Pneumologia - March 11, 2014 Category: Respiratory Medicine Source Type: research

Identification of a proteinaceous component in the leaf of moringa oleifera lam. with effects on high serum creatinine
S Sahoo, KM Raghavendra, S BiswasIndian Journal of Pharmaceutical Sciences 2014 76(1):78-81Moringa oleifera Lam. has been an important plant in the history of mankind, both for its nutritional and medicinal uses. Apart from bactericidal effects, the parts of this plant have been effectively used in the treatment of circulatory, respiratory, endocrine, digestive as well as neural disorders. Till date, though, there has been no reported activity of the involvement of any proteinaceous extract from M. oleifera on high levels of serum creatinine. To address this issue, blood samples with high levels of serum creatinine (2 mg/d...
Source: Indian Journal of Pharmaceutical Sciences - March 11, 2014 Category: Drugs & Pharmacology Authors: S SahooKM RaghavendraS Biswas Source Type: research

Regulation of Saccharomyces cerevisiae MEF1 by Hda1p affects salt resistance of bdf1Δ mutant
In this study, we reported that the salt sensitivity, mitochondrial dysfunction, and nuclear instability of bdf1Δ mutant were suppressed by HDA1 deletion or MEF1 overexpression. Hda1p overexpression inhibited the relieving effects of low‐copy overexpression of MEF1. Further analysis showed that Bdf1p regulated HDA1 transcription positively by binding to its promoter at −201 to +6 bp, whereas Hda1p modulated MEF1 expression negatively by binding to its promoter at −201 to +6 bp. These results suggested that Bdf1p likely regulated MEF1 expression negatively by regulating HDA1 positively. Mitochondrial proteomics ana...
Source: FEMS Yeast Research - March 11, 2014 Category: Research Authors: Lei Chen, Mingpeng Wang, Jin Hou, Liangyu Liu, Jiafang Fu, Yu Shen, Zhaojie Zhang, Xiaoming Bao Tags: Research Article Source Type: research

Airway Vista 2014 Speaker Abstracts
(Source: Respirology)
Source: Respirology - March 11, 2014 Category: Respiratory Medicine Tags: Airway Vista 2014 Speaker Abstracts Source Type: research

Airway Vista 2014 Poster Abstracts
(Source: Respirology)
Source: Respirology - March 11, 2014 Category: Respiratory Medicine Tags: Airway Vista 2014 Poster Abstracts Source Type: research

Author index
(Source: Respirology)
Source: Respirology - March 11, 2014 Category: Respiratory Medicine Tags: Author Index Source Type: research

Injuries and risk factors in physical education students
Conclusions Preliminary results showed that the risk of sustaining an injury and becoming ill is high for freshmen PE students. Screening at the start of the school year may play an important role in identifying the students at risk. (Source: British Journal of Sports Medicine)
Source: British Journal of Sports Medicine - March 11, 2014 Category: Sports Medicine Authors: van Beijsterveldt, A., Bliekendaal, S., Brink, M., Stubbe, J. Tags: Abstracts from the IOC World Conference on Prevention of Injury & amp; Illness in Sport, Monaco 2014 Source Type: research

Pre-participation health questionnaire in major athletic championships: feasibility and interest to determine injury and illness risk factors
Conclusions An athlete self-report PHQ was feasible and allowed for pre-participation screening of individuals at risk. Injury risk during indoor championships seems slightly lower than during outdoor championships with specific injury types that can be attributed to the indoor track conditions. (Source: British Journal of Sports Medicine)
Source: British Journal of Sports Medicine - March 11, 2014 Category: Sports Medicine Authors: Edouard, P., Branco, P., Jacobsson, J., Timpka, T., Kowalski, J., Nilsson, S., Karlsson, D., Depiesse, F., Alonso, J. Tags: Abstracts from the IOC World Conference on Prevention of Injury & amp; Illness in Sport, Monaco 2014 Source Type: research

Injury and illness risks during outdoor european athletics championships: analysis of helsinki 2012 championships
Conclusions The injury and illness surveillance system seems to have improved since the first Athletics studies. During elite Athletics Championships, the gender, age, finals and some disciplines seem to be injury risk factors. Illness risk factors remains unclear. Preventive interventions should focus on overuse injuries, hamstring strains, and adequate rehabilitation of previous injuries, and to decrease the risk of infectious diseases transmission (on appropriate event scheduling, appropriate sports clothes on weather conditions and heat acclimatization). (Source: British Journal of Sports Medicine)
Source: British Journal of Sports Medicine - March 11, 2014 Category: Sports Medicine Authors: Edouard, P., Depiesse, F., Branco, P., Alonso, J. Tags: Abstracts from the IOC World Conference on Prevention of Injury & amp; Illness in Sport, Monaco 2014 Source Type: research