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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 9.

Efficacy of Fostera® PRRS modified live virus (MLV) vaccination strategy against a Thai highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) infection
In conclusion, Fostera® PRRS MLV vaccine was able to improve the survival rate against the Thai HP-PRRSV infection in both 42- and 28-day vaccination-to-infection protocols. (Source: Tropical Animal Health and Production)
Source: Tropical Animal Health and Production - June 17, 2016 Category: Veterinary Research Source Type: research

Mycoplasma hyorhinis is a potential pathogen of porcine respiratory disease complex that aggravates pneumonia caused by porcine reproductive and respiratory syndrome virus
In this study, 383 serum samples obtained from seven herds with a history of PRDC were tested for specific antibodies to Mhr, Mycoplasma hyopneumoniae (Mhp), and porcine reproductive and respiratory syndrome virus (PRRSV). Seropositive rates of PRRSV were significantly correlated with those of Mhr (correlation coefficient, 0.862; P-value, 0.013), but not with those of Mhp (correlation coefficient, −0.555; P-value, 0.196). In vivo experiments demonstrated that pigs co-infected with Mhr and PRRSV induced more severe lung lesions than pigs infected with Mhr or PRRSV alone. These findings suggest that Mhr is closely associat...
Source: Veterinary Immunology and Immunopathology - June 17, 2016 Category: Veterinary Research Source Type: research

Factors associated with herd-level PRRSV infection and age-time to seroconversion in farrow-to-finish herds
Publication date: Available online 16 June 2016 Source:Veterinary Microbiology Author(s): C. Fablet, C. Marois-Créhan, B. Grasland, G. Simon, N. Rose Factors associated with porcine reproductive and respiratory syndrome virus (PRRSV) infection were investigated in 109 herds. Serums from four batches of pigs (4, 10, 16 and 22 weeks, 15 pigs/batch) were tested by ELISA for PRRSV antibodies. Infection by Mycoplasma hyopneumoniae (Mhp), Actinobacillus pleuropneumoniae, H1N1 and H1N2 swine influenza A viruses (swIAV) and PCV2 were detected by specific serological or PCR tests. Data related to herd characteristics, biose...
Source: Veterinary Microbiology - June 17, 2016 Category: Veterinary Research Source Type: research

Human metapneumovirus (hMPV) Infection in immunocompromised children
Human metapneumovirus (hMPV), a paramyxovirus first reported in 2001, is a major cause of upper and lower respiratory tract infection (URTI, LRTI) in children [1,2] It is the second most commonly identified pathogen after respiratory syncytial virus in lower respiratory tract illnesses, including bronchiolitis, pneumonia, and croup [3,4]. Almost all children acquire hMPV infection by 5 years of age, and infections frequently recur throughout life [5]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - June 17, 2016 Category: Virology Authors: Oded Scheuerman, Galia Barkai, Michal Mandelboim, Hagit Mishali, Gabriel Chodick, Itzhak Levy Source Type: research

Chiral separation and determination of ketamine and norketamine in hair by capillary electrophoresis
Ketamine, a phencyclidine analogue, is a dissociative anaesthetic that, in addition to analgesia, induces loss of consciousness, amnesia and immobility. First produced as Ketalar® in 1962, it was used to treat American soldiers during the Vietnam war and released for civilian use in 1970 [1]. It has been abused since the 1980s for its stimulant, dissociative and hallucinogenic effects particularly by the young generations, therefore its monitoring is valuable for traffic and workplace safety. It is nowadays still used in paediatric emergency retrieval and in veterinary surgery, because of a reduced tendency to give respir...
Source: Forensic Science International - June 17, 2016 Category: Forensic Medicine Authors: Nadia Porpiglia, Giacomo Musile, Federica Bortolotti, Elio Franco De Palo, Franco Tagliaro Source Type: research

Mandibular Advancement Splints
Although mandibular advancement splints (MAS) are not as efficacious as continuous positive airway pressure (CPAP) in reducing obstructive respiratory events, patient adherence and preference are greater than CPAP. Additionally, the effectiveness of both treatments on general health outcomes, cognitive function, and quality of life appears to be equivalent. The main barrier for the implementation of MAS treatment in clinical practice is the interindividual variability in response to MAS treatment. Several prediction tools have been proposed to enhance patient selection for MAS treatment. Phenotyping obstructive sleep apnea...
Source: Sleep Medicine Clinics - June 17, 2016 Category: Sleep Medicine Authors: Ahmad A. Bamagoos, Kate Sutherland, Peter A. Cistulli Source Type: research

Humanitarian Outreach in Cardiothoracic Surgery: From Setup to Sustainability
Publication date: Available online 17 June 2016 Source:The Annals of Thoracic Surgery Author(s): Joseph A. Dearani, Jeffrey P. Jacobs, R. Morton Bolman, JaBaris D. Swain, Luca A. Vricella, Samuel Weinstein, Emily A. Farkas, John H. Calhoon Noncommunicable diseases account for 38 million deaths each year, and approximately 75% of these deaths occur in the developing world. The most common causes include cardiovascular diseases, cancer, respiratory diseases, and diabetes mellitus. Many adults with acquired cardiothoracic disease around the world have limited access to health care. In addition, congenital heart dise...
Source: The Annals of Thoracic Surgery - June 17, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

New aspects of controlled release systems for local anaesthetics. A Review
Publication date: Available online 17 June 2016 Source:Trends in Anaesthesia and Critical Care Author(s): Alexandru Florin Rogobete, Monica Dragomirescu, Ovidiu Horea Bedreag, Dorel Sandesc, Carmen Alina Cradigati, Mirela Sarandan, Marius Papurica, Sonia Elena Popovici, Corina Vernic, Gabriela Preda Pharmacological pain control and management applied in this medical area represent the gold goal for anaesthesia and intensive care units. One of the most common methods for pain control is the use of opioids. However, there are a number of complications and side effects induced by prolonged systemic administration ...
Source: Trends in Anaesthesia and Critical Care - June 17, 2016 Category: Anesthesiology Source Type: research

The STOP BANG questionnaire and the risk of perioperative respiratory complications in urgent surgery patients: a prospective, observational study
Conclusions An elevated STOP BANG score (≥ 3) is associated with an increased risk of perioperative respiratory complications and with prolonged length of stay in urgent surgery patients. (Source: Anaesthesia, Critical Care and Pain Medicine)
Source: Anaesthesia, Critical Care and Pain Medicine - June 17, 2016 Category: Anesthesiology Source Type: research

Effect of antenatal betamethasone on blood glucose levels in women with and without diabetes
The American Congress of Obstetricians and Gynecologists (ACOG) recommends the administration of antenatal steroids to patients at risk of preterm delivery between 24-34 weeks gestation because of a known decrease in risk of respiratory distress syndrome, intraventricular hemorrhage, and neonatal death.1–3 (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - June 17, 2016 Category: Endocrinology Authors: Jennifer A. Jolley, Priya V. Rajan, Rita Petersen, Alex Fong, Deborah A. Wing Source Type: research

Nicotinamide supplementation phenocopies SIR2 inactivation by modulating carbon metabolism and respiration during yeast chronological aging
Publication date: Available online 16 June 2016 Source:Mechanisms of Ageing and Development Author(s): Ivan Orlandi, Damiano Pellegrino Coppola, Maurizio Strippoli, Rossella Ronzulli, Marina Vai Nicotinamide (NAM), a form of vitamin B3, is a byproduct and noncompetitive inhibitor of the deacetylation reaction catalyzed by Sirtuins. These represent a family of evolutionarily conserved NAD+-dependent deacetylases that are well-known critical regulators of metabolism and aging and whose founding member is Sir2 of Saccharomyces cerevisiae. Here, we investigated the effects of NAM supplementation in the context of yeast ...
Source: Mechanisms of Ageing and Development - June 17, 2016 Category: Geriatrics Source Type: research

The epidemiology and clinical features of Mycoplasma pneumoniae infection in neonates
Conclusions MP could be an important etiologic agent for respiratory tract infection in neonates. In neonates MP infection was usually associated with older age, presence of fever, and less tachypnea. MP infection in neonates tends to be a mild process. (Source: The Brazilian Journal of Infectious Diseases)
Source: The Brazilian Journal of Infectious Diseases - June 17, 2016 Category: Infectious Diseases Source Type: research

The impact of prenatally diagnosed Klinefelter Syndrome on obstetric and neonatal outcomes
Conclusion Pregnancies affected by prenatally diagnosed Klinefelter Syndrome are at an increased risk of adverse fetal and neonatal outcomes. These findings may be helpful when counseling families with pregnancies affected by fetal 47,XXY. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - June 17, 2016 Category: OBGYN Source Type: research

Bilateral intermediate uveitis with appearance of frosted branch angiitis and association with Mycoplasma pneumoniae infection: case report and review of the literature
Publication date: Available online 27 April 2016 Source:Journal of American Association for Pediatric Ophthalmology and Strabismus Author(s): Artemis Matsou, Paraskevi Riga, Maria Samouilidou, Stavros Dimitrakos, Eleftherios Anastasopoulos A 12-year-old girl presented with acute bilateral visual loss following a mild upper respiratory tract infection. Clinical examination revealed bilateral severe peripheral retinal vasculitis with an appearance of frosted branch angiitis and cystoid macular edema. All tests for etiological diagnosis were negative, apart from positive IgM and IgG antibodies for Mycoplasma pneumoniae...
Source: Journal of American Association for Pediatric Ophthalmology and Strabismus - June 17, 2016 Category: Opthalmology Source Type: research

Effects of audio coaching and visual feedback on the stability of respiration during radiotherapy
Conclusion The AC + VF method had the most beneficial effects on respiratory stability. However, coaching is not necessarily effective in all cases. Therefore, the most suitable method should be chosen on an individual basis. (Source: Japanese Journal of Radiology)
Source: Japanese Journal of Radiology - June 17, 2016 Category: Radiology Source Type: research

Pulmonary Alveolar Proteinosis Syndrome
Pulmonary alveolar proteinosis (PAP) is a rare syndrome characterized by the accumulation of surfactant in alveoli and terminal airways resulting in respiratory failure. PAP comprises part of a spectrum of disorders of surfactant homeostasis (clearance and production). The surfactant production disorders are caused by mutations in genes required for normal surfactant production. The PAP syndrome is identified based on history, radiologic, and bronchoalveolar lavage and/or histopathologic findings. The diagnosis of PAP-causing diseases in secondary PAP requires further studies. Whole-lung lavage is the current standard ther...
Source: Clinics in Chest Medicine - June 17, 2016 Category: Respiratory Medicine Authors: Takuji Suzuki, Bruce C. Trapnell Source Type: research

Cell Therapy for Bronchopulmonary Dysplasia: Promises and Perils
Despite great achievements in neonatal and perinatal medicine over the past decades, the immature lung remains the most critical organ to care for after premature birth. As a consequence, bronchopulmonary dysplasia (BPD) remains the most common complication of extreme prematurity. BPD impairs normal development and may cause lifelong morbidities. At present, there is no effective treatment for BPD – including preventing premature birth. Recent insights into the biology of stem and progenitor cells have ignited the hope of protecting the immature lung, and even regenerating an already damaged lung by using exogenous stem-...
Source: Paediatric Respiratory Reviews - June 17, 2016 Category: Respiratory Medicine Authors: Marius Alexander Möbius, Bernard Thébaud Source Type: research

Risk of asthma in heterozygous carriers for cystic fibrosis: A meta-analysis
Patients with cystic fibrosis (CF) have a higher prevalence of asthma than the background population, however, it is unclear whether heterozygous CF carriers are susceptible to asthma. Given this, a meta-analysis is necessary to determine the veracity of the association of CF heterozygosity with asthma. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - June 17, 2016 Category: Respiratory Medicine Authors: Anne Orholm Nielsen, Sadaf Qayum, Pierre Nourdine Bouchelouche, Lars Christian Laursen, Ronald Dahl, Morten Dahl Tags: Original Article Source Type: research

First report of human salivirus/klassevirus in respiratory specimens of a child with fatal adenovirus infection
Abstract Adenovirus is a leading cause of respiratory infection in children. Salivirus/klassevirus was first identified as an etiologic agent of gastroenteritis and was never reported in respiratory infection cases. The case being discussed here caught our attention because, although it is a common respiratory infection, it was fatal, while similar cases were mild. In order to find potential causes in the fatal case, we describe the clinical diagnosis and treatment, the sequencing analysis of the salivirus/klassevirus, and the co-infectious adenovirus. Metagenomics sequencing was conducted on the samples from a na...
Source: Virus Genes - June 17, 2016 Category: Genetics & Stem Cells Source Type: research

Susceptibility of porcine preimplantation embryos to viruses associated with reproductive failure
In the modern biological area, the applications of pig as a laboratory model have extensive prospects, such as gene transfer, in vitro fertilization (IVF), somatic cell nuclear transfer (SCNT), and xenotransplantation. However, the risk of pathogen transmission by porcine embryos is always a topic to be investigated, especially the viruses related to reproductive failure, for instance, pseudorabies virus (PRV), porcine reproductive and respiratory syndrome virus (PRRSV), porcine parvovirus (PPV) and porcine circovirus type 2 (PCV2). (Source: Theriogenology)
Source: Theriogenology - June 17, 2016 Category: Genetics & Stem Cells Authors: Haijing Zhao, Guangyuan Zhao, Wenjun Wang Source Type: research

Presentation of H-Type Tracheoesophageal Fistula in Two Adolescents: Delayed Diagnosis
Congenital tracheoesophageal fistula (TEF) results from the failure of lateral septation on the digestive and respiratory tracts during the embryonic stage of development. TEF is usually diagnosed during infancy, because >98% of patients with TEF are associated with atresia of the esophagus which may have potential life-threatening complications.1 The isolated fistula without esophageal atresia, termed as H-type, accounts for approximately 4% of tracheoesophageal malformations. Early diagnosis of H-type TEF can be difficult because of nonspecific symptoms. (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - June 17, 2016 Category: Perinatology & Neonatology Authors: Deniz Aygun, Senol Emre, Serdar Nepesov, Gonca Tekant, Haluk Cokugras, Yıldız Camcıoglu Tags: Brief communication Source Type: research

Underdiagnosing of Mycoplasma pneumoniae infections as revealed by use of a respiratory multiplex PCR panel
We compared a multiplex PCR diagnostic approach against specific PCR diagnosis for detection of Mycoplasma pneumoniae infection. 75% of all M. pneumoniae infections were only detected “unintentionally” by the use of the multiplex PCR indicating underdiagnosing of M. pneumoniae due to absence of clinical suspicion. (Source: Diagnostic Microbiology and Infectious Disease)
Source: Diagnostic Microbiology and Infectious Disease - June 17, 2016 Category: Microbiology Authors: Alexander Dalpke, Stefan Zimmermann, Paul Schnitzler Source Type: research

Scrub Typhus: A Clinico-Laboratory Differentiation of Children with and without Meningitis
We report the clinical and laboratory profile of 96 children with scrub typhus and compared those with and without meningitis. Twenty seven (28%) children had clinical and laboratory evidence of meningitis. The most frequent presenting features were fever (100%), meningeal signs (66.6%), nausea and vomiting (56.3%), seizures (55.5%) and altered sensorium (51.8%). The children with meningitis presented early and had significantly lower respiratory and renal impairments when compared with the non-meningitis group. Cerebrospinal fluid (CSF) analysis revealed elevated total leukocyte count (86.73 ± 94.50 cells/mm3), mon...
Source: Journal of Tropical Pediatrics - June 17, 2016 Category: Tropical Medicine Authors: Bhat, N. K., Pandita, N., Saini, M., Dhar, M., Ahmed, S., Shirazi, N., Wasim, S., Shirke, R., Chandar, V. Tags: Original Papers Source Type: research

Outcome of Severe Dengue Viral Infection-caused Acute Liver Failure in Thai Children
To determine clinical course and outcomes of liver functions in children with dengue viral infection-caused acute liver failure (ALF), the records of patients aged <15 years attending our institution during 1989–2011 were reviewed. Of the 41 ALF patients, 2, 6 and 33 patients had dengue hemorrhagic fever grade II, III and IV, respectively. Multiorgan failure including respiratory failure, massive bleeding and acute kidney injury occurred in 80.0%, 96.0% and 84.0% of the ALF cases, respectively, with an overall fatality rate of 68.3%. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were h...
Source: Journal of Tropical Pediatrics - June 17, 2016 Category: Tropical Medicine Authors: Laoprasopwattana, K., Jundee, P., Pruekprasert, P., Geater, A. Tags: Original Papers Source Type: research

IL-13(+) Type 2 Innate Lymphoid Cells Correlate with Asthma Control Status and Treatment Response.
CONCLUSIONS: ILC2s are strong responders to IL-25/IL-33 stimulation. IL-13+ILC2s show a positive correlation with the patient asthma control status and are more resistant to glucocorticoid than Th2 cells in humans. PMID: 27314535 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - June 17, 2016 Category: Molecular Biology Authors: Jia Y, Fang X, Zhu X, Bai C, Zhu L, Jin M, Wang X, Hu M, Tang R, Chen Z Tags: Am J Respir Cell Mol Biol Source Type: research

Hydrogen Sulfide: An Antiviral and Anti-inflammatory Endogenous Gasotransmitter in the Airways. Role in Respiratory Syncytial Virus Infection.
CONCLUSIONS: Overall our results indicate that H2S exerts a novel antiviral and anti-inflammatory activity in the context of RSV infection and represents a potential novel pharmacological approach to ameliorate viral-induced lung disease. PMID: 27314446 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory Cell and Molecular Biology)
Source: American Journal of Respiratory Cell and Molecular Biology - June 17, 2016 Category: Molecular Biology Authors: Ivanciuc T, Sbrana E, Ansar M, Bazhanov N, Szabo C, Casola A, Garofalo RP Tags: Am J Respir Cell Mol Biol Source Type: research

Effect of short-term ε-aminocaproic acid treatment on patients undergoing endovascular coil embolization following aneurysmal subarachnoid hemorrhage.
CONCLUSIONS In this study, short-term EACA treatment in patients who suffered from aSAH and received endovascular aneurysm repair did not decrease the risk of preinterventional rebleeding or increase the risk of thrombotic events. EACA did not affect outcome. Randomized clinical trials are required to provide robust clinical recommendation on short-term use of EACA. PMID: 27315025 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - June 17, 2016 Category: Neurosurgery Authors: Malekpour M, Kulwin C, Bohnstedt BN, Radmand G, Sethia R, Mendenhall SK, Weyhenmeyer J, Hendricks BK, Leipzig T, Payner TD, Shah MV, Scott J, DeNardo A, Sahlein D, Cohen-Gadol AA Tags: J Neurosurg Source Type: research

Topical cystic fibrosis transmembrane conductance regulator gene replacement for cystic fibrosis-related lung disease.
CONCLUSIONS: One study of liposome-based CFTR gene transfer therapy demonstrated some improvements in respiratory function in people with CF, but this limited evidence of efficacy does not support this treatment as a routine therapy at present. There was no evidence of efficacy for viral-mediated gene delivery.Future studies need to investigate clinically important outcome measures. PMID: 27314455 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - June 17, 2016 Category: Journals (General) Authors: Lee TW, Southern KW, Perry LA, Penny-Dimri JC, Aslam AA Tags: Cochrane Database Syst Rev Source Type: research

Mechanisms of BDNF Regulation in Asthmatic Airway Smooth Muscle.
Abstract Brain-derived neurotrophic factor (BDNF), a neurotrophin produced by airway smooth muscle (ASM), enhances inflammation effects on airway contractility, supporting the idea that locally produced growth factors influence airway diseases such as asthma. We endeavored to dissect intrinsic mechanisms regulating endogenous as well as inflammation (TNFα)-induced BDNF secretion in ASM of non-asthmatic vs. asthmatic () humans. We focused on specific Ca(2+) regulation- and inflammation-related signaling cascades, and quantified BDNF secretion. We find that TNFα enhances BDNF release by ASM cells, via several mecha...
Source: Am J Physiol Lung Ce... - June 17, 2016 Category: Respiratory Medicine Authors: Aravamudan B, Thompson MA, Pabelick CM, Prakash YS Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

A New Experimental Model of Acid and Endotoxin-Induced Acute Lung Injury in Rats.
In conclusion, intratracheal instillation of HCl followed by LPS at the dose of 30 μg/g b.w. results in severe diffuse alveolar damage that continues at least 72 h. This rat model of aspiration pneumonia-induced ALI will be useful for testing long-term effect of new therapeutic strategies in ALI. PMID: 27317688 [PubMed - as supplied by publisher] (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - June 17, 2016 Category: Respiratory Medicine Authors: Puig F, Herrero R, Guillamat-Prats R, Gómez MN, Tijero J, Chimenti L, Stelmakh O, Blanch L, Serrano-Mollar A, Matthay MA, Artigas A Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Macrophage Bone Morphogenic Protein Receptor 2 (BMPR2) depletion in Idiopathic Pulmonary Fibrosis (IPF) and Group III Pulmonary Hypertension.
In conclusion, our data suggest that depletion of BMPR2 mediated by a collection of miRs induced by IL-6 and subsequent STAT3 phosphorylation as a novel mechanism participating to fibroproliferative and vascular injuries in IPF. PMID: 27317687 [PubMed - as supplied by publisher] (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - June 17, 2016 Category: Respiratory Medicine Authors: Chen NY, Collum SD, Luo F, Weng T, Le TT, Hernandez AM, Philip K, Molina J, Garcia-Morales LJ, Cao Y, Ko TC, Amione-Guerra J, Al Jabbari O, Bunge RR, Youker KA, Bruckner BA, Hamid R, Davies J, Sinha N, Karmouty-Quintana H Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells.
Abstract High-dose ibuprofen, an effective anti-inflammatory therapy for the treatment of cystic fibrosis (CF), has been shown to preserve lung function in a pediatric population. Despite its efficacy, few patients receive ibuprofen treatment due to potential renal and gastrointestinal toxicity. The mechanism of ibuprofen efficacy is also unclear. We have previously demonstrated that CF microtubules are slower to reform after depolymerization compared to respective wild type controls. Slower microtubule dynamics in CF cells are responsible for impaired intracellular transport and are related to inflammatory signali...
Source: Am J Physiol Lung Ce... - June 17, 2016 Category: Respiratory Medicine Authors: Rymut SM, Kampman CM, Corey DA, Endres T, Cotton CU, Kelley TJ Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Leukotriene B4 Mediates Macrophage Influx and Pulmonary Hypertension in Bleomycin-induced Chronic Neonatal Lung Injury.
Abstract Systemically-administered bleomycin causes inflammation, arrested lung growth and pulmonary hypertension (PHT) in the neonatal rat, similar to human infants with severe bronchopulmonary dysplasia (BPD). Leukotrienes (LTs) are inflammatory lipid mediators produced by multiple cell types in the lung. The major LTs, LTB4 and cysteinyl LTs, are suggested to contribute to BPD, but their specific roles remain largely unexplored in experimental models. We hypothesized that LTs are increased in bleomycin-induced BPD-like injury and that inhibition of LT production would prevent inflammatory cell influx and thereby...
Source: Am J Physiol Lung Ce... - June 17, 2016 Category: Respiratory Medicine Authors: Ee MT, Kantores C, Ivanovska J, Wong MJ, Jain A, Jankov RP Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research

Successful Bronchoscopic Removal of a Chicken Bone Lodged in Airway for 4-Years.
PMID: 27315452 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - June 17, 2016 Category: Respiratory Medicine Authors: Mahajan AK, Khandhar SJ Tags: Am J Respir Crit Care Med Source Type: research

Development and Progression of Interstitial Lung Abnormalities in the Framingham Heart Study.
CONCLUSIONS: These findings demonstrate that ILA progression in the FHS is associated with an increased rate of pulmonary function decline and increased risk of death. PMID: 27314401 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - June 17, 2016 Category: Respiratory Medicine Authors: Araki T, Putman RK, Hatabu H, Gao W, Dupuis J, Latourelle JC, Nishino M, Zazueta OE, Kurugol S, Ross JC, San José Estépar R, Schwartz DA, Rosas IO, Washko GR, O'Connor GT, Hunninghake GM Tags: Am J Respir Crit Care Med Source Type: research

What Pneumothoraces and Fibrofolliculomas Convey: Birt-Hogg-Dubé.
PMID: 27314164 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - June 17, 2016 Category: Respiratory Medicine Authors: DeMartino ES, Wieland CN, Allen MS, Utz JP Tags: Am J Respir Crit Care Med Source Type: research

Community-based pulmonary rehabilitation in a non-healthcare facility is feasible and effective.
This study evaluated the feasibility and outcomes of a network of community-based PRPs provided in non-healthcare facilities (CPRPs). The CPRPs were established in five venues and comprised two supervised group sessions each week for 8 weeks. Participant inclusion criteria and guidelines for exercise testing and training were developed to reduce the risk of adverse events. Outcome measures included 6-min walk distance (6MWD) and health-related quality of life (chronic respiratory questionnaire (CRQ)). Respiratory-related hospital admission data were collected in the 12 months prior to and following the program. Two hundred...
Source: Chronic Respiratory Disease - June 17, 2016 Category: Respiratory Medicine Authors: Cecins N, Landers H, Jenkins S Tags: Chron Respir Dis Source Type: research

Environmental cues orchestrate regional immune surveillance and protection by pulmonary CTLs.
Abstract Tissue-resident memory CD8 T cells (TRM) provide preemptive immunity against infections that begin in peripheral tissues by guarding the site of initial pathogen exposure. Their role in immunity to respiratory virus infection is particularly important because severe damage to the alveoli can be avoided when local populations of TRM cells reduce viral burdens and dampen the responses of effector CD8 T cells in the lungs. Although a connection between rapid immune activation and early viral control is well established, the signals that keep TRM cells poised for action in the local tissues remain poorly defin...
Source: Journal of Leukocyte Biology - June 17, 2016 Category: Hematology Authors: Cauley LS Tags: J Leukoc Biol Source Type: research

Humanitarian Outreach in Cardiothoracic Surgery: From Setup to Sustainability.
Abstract Noncommunicable diseases account for 38 million deaths each year, and approximately 75% of these deaths occur in the developing world. The most common causes include cardiovascular diseases, cancer, respiratory diseases, and diabetes mellitus. Many adults with acquired cardiothoracic disease around the world have limited access to health care. In addition, congenital heart disease is present in approximately 1% of live births and is therefore the most common congenital abnormality. More than one million children in the world are born with congenital heart disease each year, and approximately 90% of these c...
Source: The Annals of Thoracic Surgery - June 17, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Dearani JA, Jacobs JP, Bolman RM, Swain JD, Vricella LA, Weinstein S, Farkas EA, Calhoon JH Tags: Ann Thorac Surg Source Type: research

Spanish Registry of Patients With Alpha-1 Antitrypsin Deficiency: Database Evaluation and Population Analysis.
CONCLUSIONS: The REDAAT registry is a useful tool for obtaining quality information about this minority disease in routine clinical practice conditions, although it is difficult to obtain follow-up data, and the representativeness of the sample included cannot be determined. PMID: 27323654 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - June 17, 2016 Category: Respiratory Medicine Authors: Lara B, Blanco I, Martínez MT, Rodríguez E, Bustamante A, Casas F, Cadenas S, Hernández JM, Lázaro L, Torres M, Curi S, Esquinas C, Dasí F, Escribano A, Herrero I, Martínez-Delgado B, Michel FJ, Rodríguez-Frías F, Miravitlles M Tags: Arch Bronconeumol Source Type: research

Tuberculosis Costs in Spain and Related Factors.
CONCLUSION: Tuberculosis gives rise to significant health spending. In order to reduce these costs, more control of transmission, and fewer hospital admissions would be required. PMID: 27323653 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)
Source: Archivos de Bronconeumologia - June 17, 2016 Category: Respiratory Medicine Authors: Gullón JA, García-García JM, Villanueva MÁ, Álvarez-Navascues F, Rodrigo T, Casals M, Anibarro L, García-Clemente MM, Jiménez MÁ, Bustamante A, Penas A, Caminero JA, Caylà J, Grupo de Trabajo del Programa Integrado de Investigación en Tuberculos Tags: Arch Bronconeumol Source Type: research

Recognizing Occupational Effects of Diacetyl: What Can We Learn from this History?
Abstract For half of the 30-odd years that diacetyl-exposed workers have developed disabling lung disease, obliterative bronchiolitis was unrecognized as an occupational risk. Delays in its recognition as an occupational lung disease are attributable to the absence of a work-related temporal pattern of symptoms; failure to recognize clusters of cases; complexity of exposure environments; and absence of epidemiologic characterization of workforces giving rise to case clusters. Few physicians are familiar with this rare disease, and motivation to investigate the unknown requires familiarity with what is known and wha...
Source: Toxicology - June 17, 2016 Category: Toxicology Authors: Kreiss K Tags: Toxicology Source Type: research

Benchmark study on fine-mode aerosol in a big urban area and relevant doses deposited in the human respiratory tract.
Abstract It is well-known that the health effects of PM increase as particle size decreases: particularly, great concern has risen on the role of UltraFine Particles (UFPs). Starting from the knowledge that the main fraction of atmospheric aerosol in Rome is characterized by significant levels of PM2.5 (almost 75% of PM10 fraction is PM2.5), the paper is focused on submicron particles in such great urban area. The daytime/nighttime, work-/weekdays and cold/hot seasonal trends of submicron particles will be investigated and discussed along with NOx and total PAH drifts demonstrating the primary origin of UFPs from c...
Source: Environmental Pollution - June 17, 2016 Category: Environmental Health Authors: Avino P, Protano C, Vitali M, Manigrasso M Tags: Environ Pollut Source Type: research