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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 9.

Upper Respiratory Infections and MRI Activity in Relapsing-Remitting Multiple Sclerosis
Conclusion: The occurrence of a URI did not increase the risk of MRI activity evaluated in an adjacent 4-week window in RRMS.Neuroepidemiology 2015;45:83-89 (Source: Neuroepidemiology)
Source: Neuroepidemiology - August 28, 2015 Category: Epidemiology Source Type: research

Functional Capacity, Health Status, and Inflammatory Biomarker Profile in a Cohort of Patients With Chronic Obstructive Pulmonary Disease.
CONCLUSIONS: In COPD, there is an association between 6MWD and the physical domains of the SF-36 and SGRQ in those patients walking < 350 m. The physical differences between patients walking < or > 350 m are not related to systemic inflammation. The association between interleukin 8 with nonphysical domains in patients with 6MWD < 350 m suggests that inflammation may play a larger role in the perceptive domain than previously recognized. PMID: 26309192 [PubMed - as supplied by publisher] (Source: Journal of Cardiopulmonary Rehabilitation and Prevention)
Source: Journal of Cardiopulmonary Rehabilitation and Prevention - August 28, 2015 Category: Rehabilitation Authors: Kohli P, Pinto-Plata V, Divo M, Malhotra A, Harris RS, Lazaar A, Flynn A, Tal-Singer R, Panettieri RA, Celli B Tags: J Cardiopulm Rehabil Prev Source Type: research

The occurrence of antibodies against Legionella pneumophila in patients with autoimmune rheumatic diseases.
CONCLUSIONS: The frequency of antibodies to L. pneumophila in our patients is comparable with healthy individuals. L. pneumophila should be recognized as a potential pathogen in patients with autoimmune rheumatic diseases. Primary disease condition, immunosuppressive therapy and other risk factors should not be neglected in these patients. PMID: 26307115 [PubMed - as supplied by publisher] (Source: Polskie Archiwum Medycyny Wewnetrznej)
Source: Polskie Archiwum Medycyny Wewnetrznej - August 28, 2015 Category: Internal Medicine Tags: Pol Arch Med Wewn Source Type: research

They can't bury you while you're still moving: a review of the European Respiratory Society statement on physical activity in COPD.
Authors: ZuWallack R Abstract Physical activity and exercise are interrelated but separate concepts. Activity refers to bodily movement produced by skeletal muscles that results in energy expenditure. Exercise is a subset of physical activity, in which generally higher levels of muscular activity are performed for a purpose, such as achieving physical fitness or winning a sporting contest. Higher exercise capacity is considered to be permissive of greater physical activity in the home and community settings. Individuals with COPD are physically inactive when compared with healthy age-matched control subjects. Furth...
Source: Polskie Archiwum Medycyny Wewnetrznej - August 28, 2015 Category: Internal Medicine Tags: Pol Arch Med Wewn Source Type: research

Noninvasive Mechanical Ventilation in Acute Respiratory Failure Patients: A Respiratory Therapist Perspective.
Authors: Hidalgo V, Giugliano-Jaramillo C, Pérez R, Cerpa F, Budini H, Cáceres D, Gutiérrez T, Molina J, Keymer J, Romero-Dapueto C Abstract Physiotherapist in Chile and Respiratory Therapist worldwide are the professionals who are experts in respiratory care, in mechanical ventilation (MV), pathophysiology and connection and disconnection criteria. They should be experts in every aspect of the acute respiratory failure and its management, they and are the ones who in medical units are able to resolve doubts about ventilation and the setting of the ventilator. Noninvasive mechanical ventilation should be the fir...
Source: Open Respiratory Medicine Journal - August 28, 2015 Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research

Ventilator-Induced Lung Injury (VILI) in Acute Respiratory Distress Syndrome (ARDS): Volutrauma and Molecular Effects.
Authors: Carrasco Loza R, Villamizar Rodríguez G, Medel Fernández N Abstract Acute Respiratory Distress Syndrome (ARDS) is a clinical condition secondary to a variety of insults leading to a severe acute respiratory failure and high mortality in critically ill patients. Patients with ARDS generally require mechanical ventilation, which is another important factor that may increase the ALI (acute lung injury) by a series of pathophysiological mechanisms, whose common element is the initial volutrauma in the alveolar units, and forming part of an entity known clinically as ventilator-induced lung injury (VILI). Inj...
Source: Open Respiratory Medicine Journal - August 28, 2015 Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research

Humidification on Ventilated Patients: Heated Humidifications or Heat and Moisture Exchangers?
Authors: Cerpa F, Cáceres D, Romero-Dapueto C, Giugliano-Jaramillo C, Pérez R, Budini H, Hidalgo V, Gutiérrez T, Molina J, Keymer J Abstract The normal physiology of conditioning of inspired gases is altered when the patient requires an artificial airway access and an invasive mechanical ventilation (IMV). The endotracheal tube (ETT) removes the natural mechanisms of filtration, humidification and warming of inspired air. Despite the noninvasive ventilation (NIMV) in the upper airways, humidification of inspired gas may not be optimal mainly due to the high flow that is being created by the leakage compensation,...
Source: Open Respiratory Medicine Journal - August 28, 2015 Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research

Pathophysiological Basis of Acute Respiratory Failure on Non-Invasive Mechanical Ventilation.
Authors: Romero-Dapueto C, Budini H, Cerpa F, Caceres D, Hidalgo V, Gutiérrez T, Keymer J, Pérez R, Molina J, Giugliano-Jaramillo C Abstract Noninvasive mechanical ventilation (NIMV) was created for patients who needed noninvasive ventilator support, this procedure decreases the complications associated with the use of endotracheal intubation (ETT). The application of NIMV has acquired major relevance in the last few years in the management of acute respiratory failure (ARF), in patients with hypoxemic and hypercapnic failure. The main advantage of NIMV as compared to invasive mechanical ventilation (IMV) is that...
Source: Open Respiratory Medicine Journal - August 28, 2015 Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research

Transfusion-Related Acute Lung Injured (TRALI): Current Concepts.
Authors: Álvarez P, Carrasco R, Romero-Dapueto C, Castillo RL Abstract Transfusion-related acute lung injury (TRALI) is a life-threatening intervention that develops within 6 hours of transfusion of one or more units of blood, and is an important cause of morbidity and mortality resulting from transfusion. It is necessary to dismiss other causes of acute lung injury (ALI), like sepsis, acute cardiogenic edema, acute respiratory distress syndrome (ARDS) or bacterial infection. There are two mechanisms that lead to the development of this syndrome: immune-mediated and no immune- mediated TRALI. A common theme among ...
Source: Open Respiratory Medicine Journal - August 28, 2015 Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research

Pathophysiological Approaches of Acute Respiratory Distress syndrome: Novel Bases for Study of Lung Injury.
Authors: Castillo RL, Carrasco Loza R, Romero-Dapueto C Abstract Experimental approaches have been implemented to research the lung damage related-mechanism. These models show in animals pathophysiological events for acute respiratory distress syndrome (ARDS), such as neutrophil activation, reactive oxygen species burst, pulmonary vascular hypertension, exudative edema, and other events associated with organ dysfunction. Moreover, these approaches have not reproduced the clinical features of lung damage. Lung inflammation is a relevant event in the develop of ARDS as component of the host immune response to various...
Source: Open Respiratory Medicine Journal - August 28, 2015 Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research

Acute Respiratory Failure: Pathophysiological Basis From A Multidisciplinary Clinical Approach.
Authors: Castillo RL PMID: 26312098 [PubMed - as supplied by publisher] (Source: Open Respiratory Medicine Journal)
Source: Open Respiratory Medicine Journal - August 28, 2015 Category: Respiratory Medicine Tags: Open Respir Med J Source Type: research

Editorial Board
(Source: Tuberculosis)
Source: Tuberculosis - August 28, 2015 Category: Respiratory Medicine Source Type: research

Sweat chloride concentrations in children with Idiopathic Nephrotic Syndrome
ConclusionsINS does not cause a false positive sweat test. Further studies should be done to objectively assess the conditions that have been reported to affect sweat chloride concentrations. Pediatr Pulmonol. © 2015 Wiley Periodicals, Inc. (Source: Pediatric Pulmonology)
Source: Pediatric Pulmonology - August 28, 2015 Category: Respiratory Medicine Authors: Lokesh Guglani, Devin Moir, Amrish Jain Tags: Original Article: Diagnostic Testing Source Type: research

Looking at the Heart of Patients with Chronic Obstructive Pulmonary Disease
Respiration (Source: Respiration)
Source: Respiration - August 28, 2015 Category: Respiratory Medicine Source Type: research

Utility of real‐time field control in T2*‐Weighted head MRI at 7T
ConclusionReal‐time field control was found to be a robust means of countering respiratory field perturbations in variable conditions encountered in high‐field brain imaging. Reducing net fluctuation, it generally expands the feasibility of high‐field T2* imaging toward challenging patients and brain regions. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc. (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - August 28, 2015 Category: Radiology Authors: Yolanda Duerst, Bertram J. Wilm, Michael Wyss, Benjamin E. Dietrich, Simon Gross, Thomas Schmid, David O. Brunner, Klaas P. Pruessmann Tags: Full Paper Source Type: research

Pressure ulcer risk assessment: retrospective analysis of Braden Scale scores in Portuguese hospitalised adult patients
ConclusionsApproximately one‐third of all participants had high risk of pressure ulcer development at admission, which led to the application of nursing preventive care. Our study demonstrated that nurses should pay special attention to patients over 50 years of age, who had significantly lower Braden Scale scores. The Braden Scale scores significantly increased in the last assessments showing that Braden Scale is sensitive to the clinical improvement of the patient. Braden Scale correlations with length of stay reveal its importance as predictor of length of stay. Relevance to clinical practiceNurses should use Braden ...
Source: Journal of Clinical Nursing - August 28, 2015 Category: Nursing Authors: Pedro Sardo, Cláudia Simões, José Alvarelhão, César Costa, Carlos J Simões, Jorge Figueira, João L Simões, Francisco Amado, António Amaro, Elsa Melo Tags: Original Article Source Type: research

Classification of different patterns of pulmonary adenocarcinomas
Expert Review of Respiratory Medicine, Ahead of Print. (Source: Expert Review of Respiratory Medicine)
Source: Expert Review of Respiratory Medicine - August 28, 2015 Category: Respiratory Medicine Tags: article Source Type: research

The disruption of mitochondrial axonal transport is an early event in neuroinflammation
Conclusions: Neuroinflammation acutely impairs axonal mitochondrial transportation, which would promote an inappropriate delivery of energy throughout axons and, by this way, contribute to axonal damage. Thus, preserving axonal mitochondrial transport might represent a promising avenue to exploit as a therapeutic target for neuroprotection in brain inflammatory diseases like multiple sclerosis. (Source: Journal of Neuroinflammation)
Source: Journal of Neuroinflammation - August 28, 2015 Category: Neurology Authors: Oihana ErreaBeatriz MorenoAlba Gonzalez-FranquesaPablo Garcia-RovesPablo Villoslada Source Type: research

Obesity in children with different risk factors for obstructive sleep apnea: a community-based study
Conclusion: We demonstrated differential risk factors for OSA in obese children, which suggest that a different mechanism may be involved in OSA development in preschool and school-age children. What is Known: Various risk factors have been reported in obese children with OSA owing to the different age and different study design. • Obese children have a higher prevalence and severity of obstructive sleep apnea (OSA). • OSA risk facto...
Source: European Journal of Pediatrics - August 28, 2015 Category: Pediatrics Source Type: research

Functional outcome of tongue motions with selective hypoglossal nerve stimulation in patients with obstructive sleep apnea
Conclusions These findings suggest that the postoperative tongue motions in upper airway stimulation are associated with the therapy outcome. The stimulation electrode placement on the hypoglossal nerve for selective muscle recruitment may play a role in the mechanism of action. (Source: Sleep and Breathing)
Source: Sleep and Breathing - August 28, 2015 Category: Respiratory Medicine Source Type: research

Erythrocyte sedimentation rate may help predict severity of obstructive sleep apnea
Conclusions ESR more closely correlated with PSG parameters recorded during sleep hypoxic episodes than hs-CRP. Moreover, the ESR may be useful to predict the OSA severity because moderate and severe OSA were independently associated with an elevated ESR. (Source: Sleep and Breathing)
Source: Sleep and Breathing - August 28, 2015 Category: Respiratory Medicine Source Type: research

Adiponectin in Asthma and Obesity: Protective Agent or Risk Factor for More Severe Disease?
Conclusions Adiponectin does not protect against the development of inflammation in the setting of asthma and may in fact exacerbate the disease via its anti-TH1 inflammatory effects, allowing for increased TH2 differentiation and a more severe allergic response. (Source: Lung)
Source: Lung - August 28, 2015 Category: Respiratory Medicine Source Type: research

Rasmussen's aneurysm: A forgotten scourge
We present a case of a young woman who presented with low-grade fever and hemoptysis. Computed tomographic (CT) angiography showed biapical cavitary lesions and actively bleeding aneurysms involving pulmonary artery, which successfully underwent glue embolization. (Source: Respiratory Medicine Case Reports)
Source: Respiratory Medicine Case Reports - August 28, 2015 Category: Respiratory Medicine Source Type: research

Positional sleep apnea: An issue of therapeutic adherence
Publication date: Available online 25 August 2015 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): P. Matos, F. Fradinho, A. Catarino, P. Lopes, M.J. Matos (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - August 28, 2015 Category: Respiratory Medicine Source Type: research

Obama's Clean Power Plan: a breath of fresh air
Publication date: Available online 28 August 2015 Source:The Lancet Respiratory Medicine Author(s): The Lancet Respiratory Medicine (Source: The Lancet Respiratory Medicine)
Source: The Lancet Respiratory Medicine - August 28, 2015 Category: Respiratory Medicine Source Type: research

Low nicotine dependence and high self-efficacy can predict smoking cessation independent of the presence of chronic obstructive pulmonary disease: a three year follow up of a population-based study
Background: Smoking is a major risk factor for chronic obstructive pulmonary disease (COPD), and smoking cessation is the only intervention that slows disease progression. It is important to know whether current factors related to smoking and smoking cessation are different among subjects with and without COPD in order to support smoking cessation. The aim of this study was to evaluate factors related to smoking cessation and to compare characteristics and nicotine dependence among smokers with and without COPD. Methods: In 2005, 1614 subjects in a population-based longitudinal study of subjects with COPD and controls were...
Source: Tobacco Induced Diseases - August 28, 2015 Category: Global & Universal Authors: Anne LindbergBenjamin NiskaCaroline StridsmanBritt-Marie EklundBerne ErikssonLinnea Hedman Source Type: research

IJERPH, Vol. 12, Pages 10635-10647: Effect of Personal Exposure to PM2.5 on Respiratory Health in a Mexican Panel of Patients with COPD
Conclusions: Exposure to PM2.5 was associated with reductions in PEF and increased respiratory symptoms in adults with COPD. The PEF reduction was observed both at morning and at night. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - August 28, 2015 Category: Environmental Health Authors: Marlene Cortez-LugoMatiana Ramírez-AguilarRogelio Pérez-PadillaRaúl Sansores-MartínezAlejandra Ramírez-VenegasAlbino Barraza-Villarreal Tags: Article Source Type: research

Mitochondrially Mediated HSF1 Activation Induces Cln-1 [Molecular Bases of Disease]
In this study, we demonstrated that mitochondrial respiratory defects induced Cln-1 transcription via reactive oxygen species (ROS)-mediated heat shock factor 1 (HSF1) activation, which contributed to hepatoma invasiveness. We first confirmed the inverse relationship between mitochondrial defects and Cln-1 induction in SNU hepatoma cells and hepatocellular carcinoma tissues. We then examined five different respiratory complex inhibitors, and complex I inhibition by rotenone most effectively induced Cln-1 at the transcriptional level. Rotenone increased both mitochondrial and cytosolic ROS. In addition, rotenone-induced Cln...
Source: Journal of Biological Chemistry - August 28, 2015 Category: Chemistry Authors: Lee, J.-H., Lee, Y.-K., Lim, J. J., Byun, H.-O., Park, I., Kim, G.-H., Xu, W. G., Wang, H.-J., Yoon, G. Tags: Signal Transduction Source Type: research

High-flow oxygen reduces 90-day mortality, compared with standard oxygen or non-invasive ventilation, in patients with acute hypoxaemic respiratory failure [synopsis]
Publication date: Available online 28 August 2015 Source:Journal of Physiotherapy Author(s): Elizabeth H Skinner (Source: Journal of Physiotherapy)
Source: Journal of Physiotherapy - August 28, 2015 Category: Physiotherapy Source Type: research

Middle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak control
ngdun Choi (Source: Experimental and Molecular Medicine)
Source: Experimental and Molecular Medicine - August 28, 2015 Category: Molecular Biology Authors: Prasannavenkatesh DuraiMaria BatoolMasaud ShahSangdun Choi Source Type: research

Abattoir surveillance demonstrates contagious bovine pleuropneumonia is widespread in Tanzania
Abstract A study was conducted to investigate the presence of contagious bovine pleuropneumonia (CBPP) in the slaughter facilities in 10 regions of Tanzania that reported pathological lesions suggestive of CBPP during meat inspection. The aim was to ascertain if slaughter facilities can be used to monitor the occurrence and spread of CBPP in the country. The study involved a questionnaire survey, clinical examination of animals for CBPP symptoms prior to slaughter and postmortem examination of the respiratory system in slaughtered cattle. A total of 12 slaughterhouses and 31 animal markets were involved in the stu...
Source: Tropical Animal Health and Production - August 28, 2015 Category: Veterinary Research Source Type: research

Increased Nucleosomes and Neutrophil Activation Link to Disease Progression in Patients with Scrub Typhus but Not Murine Typhus in Laos
This study analyzed the plasma levels of nucleosomes, FSAP-activation (nucleosome-releasing factor), and neutrophil activation, as evidenced by neutrophil-elastase (ELA) complexes, in sympatric Lao patients with scrub typhus and murine typhus. In acute scrub typhus elevated nucleosome levels correlated with lower GCS scores, raised respiratory rate, jaundice and impaired liver function, whereas neutrophil activation correlated with fibrinolysis and high IL-8 plasma levels, a recently identified predictor of severe disease and mortality. Nucleosome and ELA complex levels were associated with a 4.8-fold and 4-fold increased ...
Source: PLoS Neglected Tropical Diseases - August 28, 2015 Category: Tropical Medicine Authors: Daniel H. Paris et al. Source Type: research

Stem cells isolated from human dental pulp and amniotic fluid improve skeletal muscle histopathology in mdx/SCID mice
Conclusion: This study shows that hAFSCs and hDPSCs represent potential sources of stem cells for translational strategies to improve the histopathology and potentially alleviate the muscle weakness in patients with DMD. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 28, 2015 Category: Stem Cells Authors: Alessandra PisciottaMassimo RiccioGianluca CarnevaleAiping LuSara De BiasiLara GibelliniGiovanni La SalaGiacomo BruzzesiAdriano FerrariJohnny HuardAnto De Pol Source Type: research

Safety Profile of Certolizumab Pegol in Patients with Immune-Mediated Inflammatory Diseases: A Systematic Review and Meta-Analysis
Conclusion Safety data on CZP suggest an overall favorable tolerability profile, with infections being the most common AE. However, CZP-treated patients had a twofold higher risk of infectious SAEs than control patients. Large observational studies and data from national registries are needed to detect rare AEs, which might occur after long-term exposures to CZP. (Source: Drug Safety)
Source: Drug Safety - August 28, 2015 Category: Drugs & Pharmacology Source Type: research

Finger drop sign: Rare presentation of a common disorder
Guillain Barre syndrome (GBS) commonly presents with limb weakness and occasional cranial nerve, respiratory or autonomic involvement. Isolated or predominant bilateral finger drop as presenting feature has never been reported in the pediatric age group. (Source: Brain and Development)
Source: Brain and Development - August 28, 2015 Category: Neurology Authors: Rachana Dubey, Jaya Shankar Kaushik, Anil Israni, Lokesh Saini, Harsh Patel, Biswaroop Chakrabarty, Sheffali Gulati Tags: Case Report Source Type: research

Influenza During Pregnancy: The Role of the Nurse Practitioner
During past influenza pandemics, pregnant women had high mortality rates. Pregnant women are more severely affected by influenza related to physiologic changes to the respiratory and immune systems. Evidence suggests that receiving the influenza vaccine is safe for pregnant women, and is the best way to avoid contracting the influenza virus. Effects of influenza on the fetus are not well known, but the information that exists is largely negative. Nurse practitioners can contribute to decreased mortality by influenza in pregnant women by advocating for the safety of the vaccine and identifying early signs and symptoms of th...
Source: The Journal for Nurse Practitioners - August 28, 2015 Category: Nursing Authors: Chandra Deutscher, Laura Johnson Tags: Continuing Education Source Type: research

Thoracic trauma severity score on admission allows to determine the risk of delayed ARDS in trauma patients with pulmonary contusion
Pulmonary contusion is a major risk factor of acute respiratory distress syndrome (ARDS) in trauma patients. As this complication may appear after a free interval of 24-48h, detection of patients at risk is essential. The main objective of this study was to assess the performance of the Thoracic Trauma Severity (TTS) score upon admission in predicting delayed ARDS in blunt trauma patients with pulmonary contusion. (Source: Injury)
Source: Injury - August 28, 2015 Category: Orthopaedics Authors: Aurélien Daurat, Ingrid Millet, Jean-Paul Roustan, Camille Maury, Patrice Taourel, Samir Jaber, Xavier Capdevila, Jonathan Charbit Source Type: research

Impairments after curative intent treatment for non-small cell lung cancer: a comparison with age and gender-matched healthy controls
The aim of this study was to compare measures of exercise capacity, health-related quality of life (HRQoL), muscle force, lung function and feelings of anxiety and depression in people after curative intent treatment for NSCLC with age and gender-matched healthy controls. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 28, 2015 Category: Respiratory Medicine Authors: Vinicius Cavalheri, Sue Jenkins, Nola Cecins, Kevin Gain, Martin Phillips, Lucas H. Sanders, Kylie Hill Source Type: research

The effect of body posture during medication inhalation on exercise induced bronchoconstriction in asthmatic children
This study investigated whether inhaling a single dose of ICS in a forward leaning posture improves this protection against EIB. (Source: Respiratory Medicine CME)
Source: Respiratory Medicine CME - August 28, 2015 Category: Respiratory Medicine Authors: Reina Visser, Mariet Wind, Beike J. de Graaf, Frans.H.C. de Jongh, Job van der Palen, Bernard.J. Thio Source Type: research