Rheumatology 
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This page shows you the most recent publications within this specialty of the MedWorm directory.
59450 records returned
An improved acute gouty arthritis rat model and therapeutic effect of rhizoma dioscoreae nipponicae on acute gouty arthritis based on the protein-chip methods.
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Abstract
Rhizoma Dioscoreae Nipponicae (RDN) is an herbal medicine. In the theories of Traditional Chinese Medicine (TCM), the function of RDN is to expel wind and remove dampness. Inflammatory mechanisms play an important role in the pathological process and prognosis of acute gouty arthritis (AGA). The aim of this study was to determine the specially expressed proteins through testing the proteins of the synovium in rats with AGA. The animal model of AGA was set up by Monosodium urate crystal (MSU) combined with hypoxanthine (HX), which was ameliorated in our previous experiment. Blood samples for measurement of ...
Source: The American Journal of Chinese Medicine - February 5, 2012 Category: Complementary Medicine Authors: Yao L, Dong W, Lu F, Liu S Tags: Am J Chin Med Source Type: research
What Are the Major Diseases Involving Copper Metabolism?Email this article to a colleague.
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Discussion
Nutritional problems can occur in all parts of the world and in all socioeconomic strata. Caloric and/or protein inadequacy unfortunately plagues too many people because of inadequate supplies or availability. Supplemental food programs around the world attempt to provide appropriate nutrition, but can be stymied because of war, political instability, economic instability and many other social factors.
The most common specific nutrient deficiencies are iron and Vitamin D deficiencies. Minerals important for essential nutrition include copper, iodine, selenium and zinc. A typical mixed diet usually provides enou...
Source: PediatricEducation.org - February 5, 2012 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news
Deferiprone: Arthritis: 5 case reportsEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Immunology in clinic review series; focus on autoinflammatory diseases: update on monogenic autoinflammatory diseases: the role of interleukin (IL)-1 and an emerging role for cytokines beyond IL-1.Email this article to a colleague.
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Abstract
OTHER THEMES PUBLISHED IN THIS IMMUNOLOGY IN THE CLINIC REVIEW SERIES Allergy, Host Responses, Cancer, Type 1 diabetes and viruses, Metabolic diseases. SUMMARY: The disease-based discovery of the molecular basis for autoinflammatory diseases has led not only to a rapidly growing number of clinically and genetically identifiable disorders, but has unmantled key inflammatory pathways such as the potent role of the alarm cytokine interleukin (IL)-1 in human disease. Following its initial failures in the treatment of sepsis and the moderate success in the treatment of rheumatoid arthritis, IL-1 blocking therap...
Source: Clinical and Developmental Immunology - February 5, 2012 Category: Allergy & Immunology Authors: Goldbach-Mansky R Tags: Clin Exp Immunol Source Type: research
The autoreactivity of B cells in hereditary angioedema due to C1 inhibitor deficiency.Email this article to a colleague.
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Abstract
Patients with hereditary angioedema (HAE) tend to produce autoantibodies and have a propensity to develop immunoregulatory disorders. We characterize the profile of autoantibodies in a group of HAE patients and investigate their memory B cells' phenotype and activation status. We studied the activity status phenotype, Toll-like receptor (TLR)-9 expression and total phosphotyrosine in B cells isolated from HAE patients. Additionally, the following autoantibodies were assessed in the serum of 61 HAE patients: anti-nuclear, rheumatoid factor, anti-cardiolipin, anti-tissue transglutaminase, anti-endomysial, an...
Source: Clinical and Developmental Immunology - February 5, 2012 Category: Allergy & Immunology Authors: Kessel A, Peri R, Perricone R, Guarino MD, Vadasz Z, Novak R, Haj T, Kivity S, Toubi E Tags: Clin Exp Immunol Source Type: research
Polymorphisms of the TIM-1 gene are associated with rheumatoid arthritis in the Chinese Hui minority ethnic population.Email this article to a colleague.
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Polymorphisms of the TIM-1 gene are associated with rheumatoid arthritis in the Chinese Hui minority ethnic population.
Genet Mol Res. 2012;11(1):61-9
Authors: Xu JR, Yang Y, Liu XM, Sun JY, Wang YJ
Abstract
The T-cell immunoglobulin and mucin domain 1 (TIM-1) is known to be associated with susceptibility to rheumatoid arthritis (RA). We investigated the association of four single-nucleotide polymorphisms (SNPs) in the promoter region of the TIM-1 gene with susceptibility to RA in a Chinese Hui ethnic minority group. Using RFLP or sequence specific primer-PCR, 118 RA patients and 118 non-arthritis control i...
Source: Genetics and Molecular Research - February 3, 2012 Category: Genetics & Stem Cells Authors: Xu JR, Yang Y, Liu XM, Sun JY, Wang YJ Tags: Genet Mol Res Source Type: research
Elevated serum homocysteine levels in paediatric patients with primary Raynaud's phenomenonEmail this article to a colleague.
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CONCLUSION: Paediatric patients with RP have increased S-homocysteine levels, suggesting that homocysteine plays an important role in the development of vascular dysfunction, even at an early age (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Livedo reticularis associated with autoimmune hemolytic anemia: prolonged remission induced by peripheral blood stem cell transplantation relapse after 10 years and restoration of hemoglobin levels by rituximabEmail this article to a colleague.
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A anemia hemolítica autoimune (AHAI) é uma doença na qual são produzidos anticorpos diretamente contra as glicoproteínas adsorvidas na superfície da membrana dos eritrócitos. Algumas medicações e outras associações têm sido implicadas. Descrevemos e discutimos um caso de livedo reticular associado à AHAI tratado com transplante de células-tronco de sangue periférico (TCTSP) e que entrou em total remissão por 10 anos. Após esse período, a paciente apresentou recaída, foi tratada com anticorpo anti-CD20 (rituximabe), e atualmente encontra-se em total remissão. O papel do TCTSP e o uso de rituximabe no tra...
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Ascites due to lupus peritonitis: a rare form of onset of systemic lupus erythematosusEmail this article to a colleague.
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O lúpus eritematoso sistêmico (LES) frequentemente cursa com serosites. Cerca de 16% dos pacientes lúpicos apresentam acometimento de pleura e pericárdio. O acometimento peritoneal, no entanto, é especialmente raro, ocorrendo clinicamente em pequeno grupo de pacientes. O presente estudo trata do caso de uma paciente de 47 anos com diagnóstico de lúpus discoide que evoluiu com manifestações sistêmicas da doença, caracterizadas por distensão e dor abdominal significativas, astenia, emagrecimento, sinais propedêuticos de ascite e diarreia aguda baixa e não invasiva. Foi realizada exaustiva investigação diagnó...
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Leukopenia and thrombocytopenia induced by etanercept: two case reports and literature reviewEmail this article to a colleague.
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We report two cases of bicytopenia induced by etanercept. Both cases recovered after drug withdrawal. We discuss the need of introduction of routine laboratorial tests in patients using anti-TNF therapy, in order to identify possible hematological changes (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Current and relevant concepts in psoriatic arthritisEmail this article to a colleague.
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A artrite psoriásica (APs) é uma doença articular sistêmica e polimórfica de apresentação e curso clínico variáveis, associada a comorbidades importantes como diabetes mellitus, hipertensão arterial e dislipidemia. Para o diagnóstico precoce da doença é necessário alto grau de suspeita clínica, sobretudo quando as manifestações cutâneas são sutis e pouco definidas. Doença erosiva progressiva pode ocorrer em até metade dos pacientes, associada a alterações anatômicas e funcionais em cerca de 20%, de modo que o prognóstico da APs permanece obscuro, especialmente se diagnóstico e tratamento forem tar...
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
The role of the HLA-G gene and molecule on the clinical expression of rheumatologic diseasesEmail this article to a colleague.
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O antígeno leucocitário humano G (HLA-G) é uma molécula não clássica de complexo principal de histocompatibilidade (MHC) de classe I, caracterizada por baixo polimorfismo em sua região codificadora, um padrão de distribuição tecidual limitado em condições fisiológicas e expressão por meio de isoformas solúveis e acopladas à superfície de membranas por meio de splicing alternativo. O HLA-G é bastante conhecido por estar envolvido na indução e na manutenção da tolerância entre o sistema imunológico materno e o feto semialogênico ao nível da interface fetoplacentária. Além disso, diversos estudos a...
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Fibromuscular dysplasia: a differential diagnosis of vasculitisEmail this article to a colleague.
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A displasia fibromuscular (DFM) envolve artérias de pequeno e médio calibre e é uma causa bem conhecida de hipertensão em mulheres jovens caucasianas, quando envolve as artérias renais. A etiologia da DFM permanece desconhecida, a despeito de inúmeras teorias. Há suspeita de um componente genético, já que a doença atinge primariamente caucasianos. Também é descrita associação entre DFM e antígeno de histocompatibilidade HlA-DRw6. Os principais sítios acometidos são as artérias renais, cerebrais, carótidas, viscerais, ilíacas, subclávias, braquiais e poplíteas. As manifestações clínicas correlaciona...
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
25-Hydroxyivitamin D3 levels in patients with systemic lupus erythematosus and its association with clinical parameters and laboratory testsEmail this article to a colleague.
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CONCLUSIONS: High prevalence of 25(OH)D insufficiency/deficiency was found in patients with SLE (57.7%), with statistically significant difference as compared with the comparison group. No association of vitamin D insufficiency/deficiency was observed with the clinical variables and laboratory tests studied. The authors emphasize the importance of determining 25(OH)D serum levels in all patients with SLE, regardless of where they live and time to disease diagnosis (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Prevalence and genetic diversity of torque teno virus in patients with systemic lupus erythematosus in a reference service in Mato Grosso do SulEmail this article to a colleague.
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CONCLUSION: Further studies on the presence of TTV in SLE patients are required (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Reduction in alveolar bone density of patients with juvenile idiopathic arthritisEmail this article to a colleague.
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CONCLUSION: ABD was lower in patients with JIA and seemed to be influenced by neither medication nor rheumatic disease activity. In addition, no correlation was observed between ABD and periodontal and rheumatologic clinical parameters (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
CysLT1 receptor inhibition in patients with Raynaud's phenomenon: capillaroscopic evidence of the role of leukotrieneEmail this article to a colleague.
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CONCLUSION: The use of montelukast modified the capillary abnormalities observed on nailfold capillaroscopy of patients with Raynaud's phenomenon (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Using questionnaires to assess the quality of life and multidimensionality of fibromyalgia patientsEmail this article to a colleague.
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CONCLUSIONS: All instruments had good discriminating power (P < 0.05), especially FIQ, VAS and PSI, whose areas under the ROC curve were greater (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Switching between anti-TNF-alpha agents does not improve functional capacity in patients with long-standing and active rheumatoid arthritisEmail this article to a colleague.
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CONCLUSION: Switching between anti-TNF-alpha agents is a valid strategy to control disease activity, despite the low likelihood of remission and no significant improvement in functional capacity (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
The therapeutic potential of the HLA-G moleculeEmail this article to a colleague.
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(Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
New Heart Failure Risks: Fractures and Memory ProblemsEmail this article to a colleague.
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Title: New Heart Failure Risks: Fractures and Memory ProblemsCategory: Health NewsCreated: 2/3/2012 11:01:00 AMLast Editorial Review: 2/3/2012 (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - February 3, 2012 Category: Rheumatology Source Type: news
Neuromodulators for pain management in rheumatoid arthritisEmail this article to a colleague.
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(Source: Prescriber)
Source: Prescriber - February 3, 2012 Category: Primary Care Tags: Cochrane Library Source Type: research
Infections in patients with giant cell arteritis: Might hypogammaglobulinemia induced by corticosteroids be a risk factor?Email this article to a colleague.
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(Source: Arthritis Care and Research)
Source: Arthritis Care and Research - February 3, 2012 Category: Rheumatology Authors: Francisco José Fernández‐Fernández Tags: Letter to the editor Source Type: research
Associations of varus thrust and alignment with pain in knee osteoarthritisEmail this article to a colleague.
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Conclusion:In those with knee OA, varus thrust and possibly varus static alignment, were associated with pain, specifically during weight‐bearing activities. Treatment of varus thrust (e.g. via bracing or gait modification) may lead to improvement of symptoms. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 3, 2012 Category: Rheumatology Authors: Grace H. LoWilliam F. HarveyTimothy E. McAlindon Tags: Full Length Source Type: research
Very high level of anti‐citrullinated peptide antibodies associate with HLA‐DRB1*15 non‐shared epitope allele in patients with rheumatoid arthritisEmail this article to a colleague.
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Conclusion: Our data indicate that HLA‐DRB1*15 may promote the production of high ACPA level. Due to high value of ACPA level scores in the 2010 ACR/EULAR classification criteria of RA, the presence of HLA‐DRB1*15 may, at least in part, contribute to fulfilling the criteria of RA. This illustrates the complex nature of the genetic regulation of ACPA level. Additional mechanistic studies on the regulation of ACPA and ACPA‐positive RA are pending. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 3, 2012 Category: Rheumatology Authors: Judit LakiEmeli LundströmOmri SnirJohan RönnelidIzabella GanjiAnca I CatrinaCamilla BengtssonSaedis SaevarsdottirMarius C. WickLars AlfredssonLars KlareskogLeonid Padyukov Tags: Full Length Source Type: research
Joint immobilisation prevents murine osteoarthritis, and reveals the highly mechanosensitive nature of protease expression in vivoEmail this article to a colleague.
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Conclusion: Gene expression in the joint following induction of OA is rapid and highly mechanosensitive. Regulated genes include the known pathogenic protease Adamts5. Targeting the mechanosensing mechanisms of joint tissues could offer new strategies for disease modification. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 3, 2012 Category: Rheumatology Authors: Annika BurleighAnastasios ChanalarisMatthew GardinerClare DriscollOlga BorucJeremy SaklatvalaTonia L Vincent Tags: Full Length Source Type: research
Pregnancy outcome in women exposed to leflunomide before or during pregnancyEmail this article to a colleague.
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Conclusion: These data provide additional reassurance to women who inadvertently become pregnant while taking leflunomide and who undergo the washout procedure, and women who discontinue the medication prior to conception but have no pre‐pregnancy documentation of drug clearance. However, until more conclusive data become available, women on therapy should be advised to use contraceptive methods and avoid pregnancy. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 3, 2012 Category: Rheumatology Authors: M CassinaDL JohnsonLK RobinsonSR BraddockR XuJ Lopez‐JimenezN MirrasoulE SalasYJ LuoKL JonesCD Chambersand Tags: Full Length Source Type: research
An in vivo investigation of the initiation and progression of subchondral cysts in a rodent model of secondary osteoarthritisEmail this article to a colleague.
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Conclusions:
This study provides insight into the mechanisms leading to SBC formation in knee OA. The expansion of these lesions is due to stress-induced bone resorption from the incurred mechanical instability. Therefore we suggest these lesions can be more accurately described as a form of OA-induced osteonecrosis, rather than 'subchondral cysts'. (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - February 3, 2012 Category: Rheumatology Authors: David McErlainVeronica UliciMark DarlingJoe GatiVasek PitelkaFrank BeierDavid Holdsworth Source Type: research
Varus Ankle and Osteochondral Lesions of the TalusEmail this article to a colleague.
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To our knowledge, little is reported about the management of the patients with combined symptomatic osteochondral lesions of the talus (OLT) and varus ankle malalignment. Treatment strategies for symptomatic OLTs are relatively well described in the orthopaedic literature. While less defined than the surgical management of OLTs, realignment procedures for the varus ankle and hindfoot have also been studied and reported in some detail, albeit with a focus on management of ankle arthritis. In this article we review practical concepts from the orthopaedic literature that may be applied when treating patients with concomitant ...
Source: Foot and Ankle Clinics - February 2, 2012 Category: Orthopaedics Authors: Mark E. Easley, J. Carr Vineyard Source Type: research
Health Tip: Help Prevent a Stress FractureEmail this article to a colleague.
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Take it slow when starting an exercise program (Source: Orthopedics News - Doctors Lounge)
Source: Orthopedics News - Doctors Lounge - February 2, 2012 Category: Orthopaedics Authors: webmaster at doctorslounge.com Tags: Orthopedics, Rheumatology, Sports Medicine, FYI, Source Type: news
The Clinical Spectrum of Juvenile Idiopathic Arthritis in a Large Urban PopulationEmail this article to a colleague.
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Abstract Urban populations present particular challenges for medical providers. Patients are extremely diverse, with varied socioeconomic,
cultural, and ethnic backgrounds. Physicians caring for children with juvenile idiopathic arthritis must be prepared to interact
effectively with many types of families who bring with them varied experiences and expectations. Pediatric rheumatologists
should be familiar with patient characteristics that can influence disease outcomes. Access to care is affected by place of
residence, referral delays, parental education, and the child’s insurance status. Patients of diff...
Source: Current Rheumatology Reports - February 2, 2012 Category: Rheumatology Tags: Current Rheumatology Reports Source Type: research
Erratum to: Effect of music on anxiety and pain during joint lavage for knee osteoarthritisEmail this article to a colleague.
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Content Type Journal ArticleCategory ErratumPages 1-1DOI 10.1007/s10067-012-1944-1Authors
Sébastien Ottaviani, Sorbonne Paris Cité, Assistance Publique-Hôpitaux de Paris, Hôpital Lariboisière, Fédération de Rhumatologie, Université Paris Diderot, 75010 Paris, FranceJean-Luc Bernard, Sorbonne Paris Cité, Assistance Publique-Hôpitaux de Paris, Hôpital Lariboisière, Fédération de Rhumatologie, Université Paris Diderot, 75010 Paris, FranceThomas Bardin, Sorbonne Paris Cité, Assistance Publique-Hôpitaux de Paris, Hôpital Lariboisière, Fédération de Rhumatologie, Université Paris Diderot, 75010 Paris, F...
Source: Clinical Rheumatology - February 2, 2012 Category: Rheumatology Tags: Clinical Rheumatology Source Type: research
Allogeneic transplantation of umbilical cord-derived mesenchymal stem cells for diffuse alveolar hemorrhage in systemic lupus erythematosusEmail this article to a colleague.
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This study aimed to assess the efficacy of UC-MSCT in the
treatment of SLE-associated DAH. Four SLE patients complicated with DAH, who underwent UC-MSCT, were included. Clinical changes
before and after transplantation were assessed by measurements of hemoglobin, platelet level, oxygen saturation, and serological
factors. High-resolution CT (HRCT) scans of the chest were performed to evaluate pulmonary manifestation. All the four patients
showed dramatic improvements of their clinical manifestations. Hemoglobin was elevated after UC-MSCT and was sustained at
a normal level 6 months after UC-MSCT in the four patie...
Source: Clinical Rheumatology - February 2, 2012 Category: Rheumatology Tags: Clinical Rheumatology Source Type: research
Clinical and radiographic results from a 2-year comparison of once-weekly versus twice-weekly administration of etanercept in biologics-naive patients with rheumatoid arthritisEmail this article to a colleague.
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Conclusions These results suggest that, in terms of DAS-28 remission, OW therapy can efficiently substitute for TW therapy in biologics-naive
patients with RA. However, TW therapy was indispensable in preventing the worsening of joint damage.
Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s10165-011-0591-8Authors
Takahiko Wada, Department of Orthopaedic Surgery, Hirakata Hospital, Kansai Medical University, 2-3-1 Shin-machi, Hirakata, Osaka 573-1191, JapanYonsu Son, Department of Rheumatology, Hirakata Hospital, Kansai Medical University, 2-3-1 Shin-machi, Hirakata, Osaka 5...
Source: Modern Rheumatology - February 2, 2012 Category: Rheumatology Tags: Modern Rheumatology Source Type: research
Screening for PAH in Systemic Sclerosis: Does It Matter?Screening for PAH in Systemic Sclerosis: Does It Matter?Email this article to a colleague.
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Dr. Kevin Deane appraises new data on PAH detection programs in patients with systemic sclerosis. Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 2, 2012 Category: Consumer Health News Tags: Rheumatology Viewpoint Source Type: news
Dyspnea Caused by Atlantoaxial Subluxation in a Patient with Rheumatoid ArthritisEmail this article to a colleague.
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We report a patient with rheumatoid arthritis whose chief complaint was dyspnea on arrival to the emergency department (ED). After further investigation, spinal cord compression caused by atlantoaxial subluxation was diagnosed. This is an uncommon but important case that ED physicians should be aware of. (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 2, 2012 Category: Allergy & Immunology Source Type: research
Epidemiology, Clinical Manifestations, and Long-Term Outcomes of a Major Outbreak of Chikungunya in a Hamlet in Sri Lanka, in 2007: A Longitudinal Cohort StudyEmail this article to a colleague.
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Chikungunya outbreaks occurred in the central province, Sri Lanka in 2006. This community-based study reports the epidemiology and the natural history of the infection from an affected village. Of the 199 families and 1001 individuals in the village, 159 (80%) and 513 (51%) were affected, respectively, comprising 237 (46%) males with peak incidence at 40–50 years. The acute illness caused polyarthritis in 233 (46%), and of them 230 (98%) progressed to chronic arthritic disability (CAD). Of the CAD patients, 102 (44%) had recovered in 141 days (range 30–210 days) from the disability stat...
Source: Clinical and Developmental Immunology - February 2, 2012 Category: Allergy & Immunology Source Type: research
Immunology in clinic review series; focus on autoinflammatory diseases: update on monogenic autoinflammatory diseases: the role of interleukin (IL)‐1 and an emerging role for cytokines beyond IL‐1Email this article to a colleague.
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OTHER THEMES PUBLISHED IN THIS IMMUNOLOGY IN THE CLINIC REVIEW SERIESAllergy, Host Responses, Cancer, Type 1 diabetes and viruses, Metabolic diseases.SummaryThe disease‐based discovery of the molecular basis for autoinflammatory diseases has led not only to a rapidly growing number of clinically and genetically identifiable disorders, but has unmantled key inflammatory pathways such as the potent role of the alarm cytokine interleukin (IL)‐1 in human disease. Following its initial failures in the treatment of sepsis and the moderate success in the treatment of rheumatoid arthritis, IL‐1 blocking therapies had a renai...
Source: Clinical and Experimental Immunology - February 2, 2012 Category: Allergy & Immunology Authors: R. Goldbach‐Mansky Source Type: research
Those Living In Poor Neighbourhoods Suffer Higher Incidence Of ArthritisEmail this article to a colleague.
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Results revealed that people who live in socially disadvantaged areas were 42 per cent more at risk of getting arthritis than people in more affluent areas. The study revealed more than 30 per cent of people living in socially disadvantaged areas reported having arthritis, as opposed to 18.5 per cent in the more affluent areas. Led by the University of Melbourne, Deakin University and Queensland University of Technology, the study was published in the international journal Arthritis Care & Research... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 2, 2012 Category: Consumer Health News Tags: Arthritis / Rheumatology Source Type: news
Gleevec Approval Widened to Include Rare CancerEmail this article to a colleague.
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Title: Gleevec Approval Widened to Include Rare CancerCategory: Health NewsCreated: 2/1/2012 4:06:00 PMLast Editorial Review: 2/2/2012 (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - February 2, 2012 Category: Rheumatology Source Type: news
infliximab, RemicadeEmail this article to a colleague.
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Title: infliximab, RemicadeCategory: MedicationsCreated: 12/13/1999 9:40:00 PMLast Editorial Review: 2/2/2012 (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - February 2, 2012 Category: Rheumatology Source Type: news
sulfamethoxazole and trimethoprim, Bactrim, SeptraEmail this article to a colleague.
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Title: sulfamethoxazole and trimethoprim, Bactrim, SeptraCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 2/2/2012 (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - February 2, 2012 Category: Rheumatology Source Type: news
estrogens conjugated, PremarinEmail this article to a colleague.
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Title: estrogens conjugated, PremarinCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 2/2/2012 (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - February 2, 2012 Category: Rheumatology Source Type: news
Tumor necrosis factor-like weak inducer of apoptosis and its potential roles in lupus nephritisEmail this article to a colleague.
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Abstract
Introduction Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) is a recently identified proinflammatory cytokine of the
TNF superfamily that functions through binding to Fn14 receptor in target cells. TWEAK has multiple biological activities.
Studies show that TWEAK plays an important role in immune inflammatory diseases. Recent work has revealed that TWEAK may play
an important role in the pathogenesis of kidney damage, including in systemic lupus erythematosus (SLE), where its concentration
in urine was correlated with the level of activity of lupus nephritis (LN).
Objec...
Source: Inflammation Research - February 2, 2012 Category: Research Tags: Inflammation Research Source Type: research
Increased serum soluble CD147 levels in patients with systemic sclerosis: association with scleroderma renal crisisEmail this article to a colleague.
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This study aimed to determine serum
soluble CD147 (sCD147) levels and their clinical associations in patients with systemic sclerosis (SSc). Serum sCD147 levels
were examined by enzyme-linked immunosorbent assay in 61 SSc patients and 24 healthy individuals. Serum sCD147 levels were
significantly elevated in SSc patients compared with healthy individuals (P < 0.001). Among patients with SSc, there were no differences in serum sCD147 levels between limited cutaneous (n = 30) and diffuse cutaneous SSc (n = 31). Patients with SSc who had elevated sCD147 levels had renal crisis more often than those with norm...
Source: Clinical Rheumatology - February 2, 2012 Category: Rheumatology Tags: Clinical Rheumatology Source Type: research
Stinging Nettle is effective in treating BPH, arthritis, and aids post-partum mothersEmail this article to a colleague.
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(NaturalNews)Many people can relate to the experience of brushing up against a stinging nettle plant in a pasture or meadow. The unforgettable chemical burn creates mean welts which can sting for a week. However, stinging nettle (Urtica dioica) has such healing capabilities that... (Source: NaturalNews.com)
Source: NaturalNews.com - February 2, 2012 Category: Consumer Health Advice Source Type: news
Use of non-steroidal anti-inflammatory drugs in pregnancy: impact on the fetus and newborn.Email this article to a colleague.
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This article discusses in detail the placental transfer and metabolism of NSAIDs, and the adverse impact of prenatal NSAID exposure on the offspring.
PMID: 22299823 [PubMed - as supplied by publisher] (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - February 2, 2012 Category: Drugs & Pharmacology Authors: Antonucci R, Zaffanello M, Elisabetta P, Porcella A, Cuzzolin L, Pilloni MD, Fanos V Tags: Curr Drug Metab Source Type: research
Sports Activity After Short-Stem Hip ArthroplastyEmail this article to a colleague.
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Conclusion: Patients with a short-stem hip implant can return to a good level of activity postoperatively. Participation in sports almost reached similar levels as preoperatively but with a shift from high- to low-impact activities. This seems desirable from a surgeon’s point of view but should also be communicated to the patient before hip replacement. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - February 2, 2012 Category: Sports Medicine Authors: Schmidutz, F., Grote, S., Pietschmann, M., Weber, P., Mazoochian, F., Fottner, A., Jansson, V. Tags: Hip/groin, Operative research-article Source Type: research
Editorial: Policy Challenges for the Pediatric Rheumatology WorkforceEmail this article to a colleague.
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Dr. Henrickson presents a thoughtful three part analysis of current challenges to pediatric rheumatologists regarding barriers to access to care for children with rheumatic disease and to achieving optimal clinical outcomes. 1-3 He then presents some possible solutions. He has initiated an important conversation that has the potential to impact the future of our discipline. (Source: Pediatric Rheumatology)
Source: Pediatric Rheumatology - February 2, 2012 Category: Rheumatology Authors: Carol Lindsley Source Type: research
Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodiesEmail this article to a colleague.
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Conclusions:
Isolated in vivo exposure to NETs is insufficient to break tolerance and may involve additional factors that have yet to be identified. (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - February 2, 2012 Category: Rheumatology Authors: Chih Long LiuStephanie TangsombatvisitJacob RosenbergGil MandelbaumEmily GillespieOr GozaniAsh AlizadehPaul Utz Source Type: research
