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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 2.

ARTHRITIS PAIN RELIEF (Acetaminophen) Tablet, Film Coated, Extended Release [Kroger Company]
Updated Date: Jan 25, 2013 EST
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - January 25, 2013 Category: Drugs & Pharmacology Source Type: news

Researchers identify new target for rheumatoid arthritis
(Hospital for Special Surgery) Researchers at Hospital for Special Surgery have identified a potential new target for drugs to treat patients with rheumatoid arthritis, a protein known as IRHOM2. The finding could provide an effective and potentially less toxic alternative therapy to tumor necrosis factor-alpha blockers, the mainstay of treatment for rheumatoid arthritis, and could help patients who do not respond to this treatment. Efforts to develop drugs that hone in on this new target are underway.
Source: EurekAlert! - Medicine and Health - January 25, 2013 Category: Global & Universal Source Type: news

Grant to fund development of drug candidates for rheumatoid arthritis, neurodegenerative disorders
(Scripps Research Institute) Scientists from the Florida campus of the Scripps Research Institute have been awarded approximately $1.2 million from the National Institute of General Medical Sciences of the National Institutes of Health to identify, test and develop a series of drug candidates for a number of diseases, including rheumatoid arthritis, heart disease and several neurodegenerative disorders.
Source: EurekAlert! - Medicine and Health - January 25, 2013 Category: Global & Universal Source Type: news

JCI early table of contents for Jan. 25, 2013
(Journal of Clinical Investigation) This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, January 25, 2013, in the JCI: Prostate cancer cells thrive on stress; An important LINC in human hearing; Green tea and Vardenafil: a killer chemotherapy combo; Researchers explain how coal tar treats eczema; iRHOM2: the newest gadget in rheumatoid arthritis; and many more.
Source: EurekAlert! - Cancer - January 25, 2013 Category: Cancer & Oncology Source Type: news

Method patent issued for investigational new class of pain medication
(NIH/National Institute of Dental and Craniofacial Research) The US Patent and Trademark Office recently issued a patent to the US Department of Health and Human Services involving resiniferatoxin, or RTX, an experimental compound that represents a potential new class of drugs to alleviate the intractable pain that can occur in people with advanced cancer, severe arthritis, and other extremely chronic conditions.
Source: EurekAlert! - Social and Behavioral Science - January 25, 2013 Category: Global & Universal Source Type: news

Defining the Aromatase Inhibitor Musculoskeletal SyndromeDefining the Aromatase Inhibitor Musculoskeletal Syndrome
Musculoskeletal symptoms can be severe enough to induce women to stop taking aromatase inhibitors. Medscape Rheumatology
Source: Medscape Today Headlines - January 24, 2013 Category: Consumer Health News Tags: Rheumatology Viewpoint Source Type: news

Positive CHMP opinion for Ilaris®
Novartis has announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion for the use of llaris (canakinumab, ACZ885) in the treatment of patients with acute gouty arthritis who suffer frequent attacks, and whose symptoms cannot or should not be managed with current treatment options.
Source: Pharmacy Europe - January 24, 2013 Category: Drugs & Pharmacology Source Type: news

Newly Approved Oral Medication Slows Rheumatoid Arthritis Joint Damage
A Phase 3 clinical trial demonstrates that tofacitinib improves disease activity and inhibits progression of joint damage in rheumatoid arthritis (RA) patients who did not respond to methotrexate (MTX). Results of the 12-month interim analysis of the efficacy of tofacitinib appear in Arthritis & Rheumatism, a journal published by Wiley on behalf of the American College of Rheumatology (ACR). RA is a chronic, autoimmune disease that causes inflammation, pain and swelling of the joints. Over time, RA may destroy joints, impair daily function, and lead to significant disability...
Source: Health News from Medical News Today - January 24, 2013 Category: Consumer Health News Tags: Arthritis / Rheumatology Source Type: news

EU Gives Initial Okay to Canakinumab for Gouty Arthritis EU Gives Initial Okay to Canakinumab for Gouty Arthritis
Drug regulators in the European Union have given canakinumab preliminary approval for use in treating acute gouty arthritis. Medscape Medical News
Source: Medscape Today Headlines - January 24, 2013 Category: Consumer Health News Tags: Rheumatology News Source Type: news

30 Days to Better Sleep: Quiet Your Restless Legs
Resting at night depends on getting to sleep easily and staying asleep. Aside from insomnia, one of the sleep disorders that can make it difficult to fall asleep is restless legs syndrome (RLS). What is this condition and what are the major causes of RLS? Frequent bouts of restlessness in your legs may require treatment, so what are the options? Learning if you have RLS and finding an effective therapy will certainly help you to sleep better. Restless legs syndrome, or RLS, is a commonly experienced but infrequently discussed condition. It may affect up to 20% of adults. It typically involves an uncomfortable or disagreea...
Source: About Sleep Disorders - January 24, 2013 Category: Sleep Medicine Source Type: news

Research: Lupus drugs carry no significant cancer risk for patients
(McGill University Health Centre) People who take immunosuppressive drugs to treat lupus do not necessarily increase their cancer risk according to new research led by scientists at the Research Institute of the McGill University Health Centre. This landmark study, which was published in Annals of the Rheumatic Diseases this month, addresses long-standing fears of a link between lupus medication and cancer.
Source: EurekAlert! - Medicine and Health - January 24, 2013 Category: Global & Universal Source Type: news

Researchers uncover gene's role in rheumatoid arthritis, findings pave way for new treatments
(University of Michigan Health System) University of Michigan research sheds new light on why certain people are more likely to suffer from rheumatoid arthritis -- paving the way to explore new treatments for both arthritis and other autoimmune diseases.
Source: EurekAlert! - Medicine and Health - January 24, 2013 Category: Global & Universal Source Type: news

Newly approved oral medication slows rheumatoid arthritis joint damage
(Wiley) A Phase 3 clinical trial demonstrates that tofacitinib improves disease activity and inhibits progression of joint damage in rheumatoid arthritis patients who did not respond to methotrexate. Results of the 12-month interim analysis of the efficacy of tofacitinib appear in Arthritis & Rheumatism, a journal published by Wiley on behalf of the American College of Rheumatology.
Source: EurekAlert! - Medicine and Health - January 24, 2013 Category: Global & Universal Source Type: news

Rheumatoid Arthritis Awareness Day
First Awareness Day For Rheumatoid Arthritis Established By Rheumatoid Patient Foundation.
Source: Disabled World - January 23, 2013 Category: Disability Tags: Disability Awareness Source Type: news

I'll defy doctors to ride in Rio Paralympics despite suffering from crippling arthritis
WHEN Roberta Sheffield explains that she suffers from arthritis the response is often predictable - that she is too young for the disease.
Source: Daily Express - Health - January 22, 2013 Category: Consumer Health News Source Type: news

Scientists Identify Epigenetic Changes That Referee Genetic Risk, May Promote Rheumatoid Arthritis
In one of the first genome-wide studies to hunt for both genes and their regulatory "tags" in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic risk for rheumatoid arthritis (RA), an immune disorder that afflicts an estimated 1.5 million American adults. By teasing apart the tagging events that result from RA from those that help cause it, the scientists say they were able to spot tagged DNA sequences that may be important for the development of RA...
Source: Health News from Medical News Today - January 22, 2013 Category: Consumer Health News Tags: Arthritis / Rheumatology Source Type: news

Loneliness corrodes health
COLUMBUS, Ohio, Jan. 22 (UPI) -- Loneliness boosts inflammation, which is linked to coronary heart disease, type 2 diabetes, arthritis and Alzheimer's disease, U.S. researchers suggest.
Source: Health News - UPI.com - January 22, 2013 Category: Consumer Health News Source Type: news

Immune cell death defects linked to autoimmune diseases
(Walter and Eliza Hall Institute) Melbourne researchers have discovered that the death of immune system cells is an important safeguard against the development of diseases such as type 1 diabetes, rheumatoid arthritis and lupus, which occur when the immune system attacks the body's own tissues.
Source: EurekAlert! - Medicine and Health - January 22, 2013 Category: Global & Universal Source Type: news

Altering Gut Microbes Protects Against Disease, Supporting The 'Hygiene Hypothesis'
Early life exposure to normal bacteria of the GI tract (gut microbes) protects against autoimmune disease in mice, according to research published on-line in the journal Science. The study may also have uncovered reasons why females are at greater risk of autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and lupus compared to males. Researchers from The Hospital for Sick Children (SickKids) found that when female mice at high risk of autoimmune (type 1) diabetes were exposed to normal gut bacteria from adult male mice, they were strongly protected against the disease...
Source: Health News from Medical News Today - January 21, 2013 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

CHMP recommends extension of canakinumab (Ilaris®) license to include treatment of gouty arthritis
Source: European Medicines Agency Area: News The Committee for Medicinal Products for Human Use (CHMP) has recommended the adoption of a new indication for canakinumab (Ilaris®), as follows:   "Ilaris is indicated for the symptomatic treatment of adults patients with frequent gouty arthritis attacks (at least 3 attacks in the previous 12 months) in whom non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine are contraindicated, are not tolerated, or do not provide an adequate response, and in whom repeated courses of corticosteroids are not appropriate".   Detailed conditions for the use of this...
Source: NeLM - News - January 21, 2013 Category: Drugs & Pharmacology Source Type: news

CHMP recommends extension of adalimumab (Humira) license to include treatment of younger patients with polyarticular juvenile idiopathic arthritis
Source: European Medicines Agency Area: News The Committee for Medicinal Products for Human Use (CHMP) has recommended a variation to the terms of the marketing authorisation for adalimumab (Humira®), so that it is indicated for the treatment of active polyarticular juvenile idiopathic arthritis in children and adolescents aged 2 to 17 years (currently licensed for use within this indication for those aged 4-17 years).   Detailed conditions for the use of this product will be described in the updated summary of product characteristics (SmPC), which will be published in the revised European public assessment rep...
Source: NeLM - News - January 21, 2013 Category: Drugs & Pharmacology Source Type: news

NICE consults on draft rheumatoid arthritis quality standard
Source: NICE Area: News NICE has launched a consultation on its draft quality standard for rheumatoid arthritis, which is open until 18th February 2013. Please see the link below for details.
Source: NeLM - News - January 21, 2013 Category: Drugs & Pharmacology Source Type: news

Vitamin D and Rheumatoid ArthritisVitamin D and Rheumatoid Arthritis
Should patients with RA receive vitamin D supplementation? Therapeutic Advances in Endocrinology and Metabolism
Source: Medscape Today Headlines - January 20, 2013 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Epigenetics explains rheumatism? Genes and their regulatory 'tags' conspire to promote rheumatoid arthritis
In one of the first genome-wide studies to hunt for both genes and their regulatory “tags” in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic risk for rheumatoid arthritis (RA). The scientists say they were able to spot tagged DNA sequences that may be important for the development of RA.
Source: ScienceDaily Headlines - January 20, 2013 Category: Science Source Type: news

Study Details What Activates Disease-Causing Genes
With rheumatoid arthritis patients, researchers at the Johns Hopkins University School of Medicine and the Karolinska Institute evaluated the chemical tags that tell genes to be active or not.
Source: NYT Health - January 20, 2013 Category: Consumer Health News Authors: By GINA KOLATA Tags: Genetics and Heredity United States Arthritis Research Karolinska Institute Sweden Johns Hopkins University Source Type: news

Genes And Their Regulatory 'Tags' Conspire To Promote Rheumatoid Arthritis
In one of the first genome-wide studies to hunt for both genes and their regulatory "tags" in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic risk for rheumatoid arthritis (RA), an immune disorder that afflicts an estimated 1.5 million American adults. By teasing apart the tagging events that result from RA from those that help cause it, the scientists say they were able to spot tagged DNA sequences that may be important for the development of RA. And they suspect their experimental method can be applied to predict similar risk factors for other common, noninf...
Source: NHGRI-Related News - January 20, 2013 Category: Genetics & Stem Cells Source Type: news

Genes and their regulatory 'tags' conspire to promote rheumatoid arthritis
(Johns Hopkins Medicine) In one of the first genome-wide studies to hunt for both genes and their regulatory "tags" in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic risk for rheumatoid arthritis (RA). By teasing apart the tagging events that result from RA from those that help cause it, the scientists say they were able to spot tagged DNA sequences that may be important for the development of RA.
Source: EurekAlert! - Biology - January 20, 2013 Category: Biology Source Type: news

Chronic Inflammation May Be Relieved By Mindfulness Meditation
People suffering from chronic inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease and asthma - in which psychological stress plays a major role - may benefit from mindfulness meditation techniques, according to a study by University of Wisconsin-Madison neuroscientists with the Center for Investigating Healthy Minds at the Waisman Center. Mindfulness-based stress reduction, originally designed for patients with chronic pain, consists of continuously focusing attention on the breath, bodily sensations and mental content while seated, walking or practicing yoga...
Source: Health News from Medical News Today - January 18, 2013 Category: Consumer Health News Tags: Psychology / Psychiatry Source Type: news

Extra-articular Manifestations in SpondyloarthritisExtra-articular Manifestations in Spondyloarthritis
What are the extra-articular manifestations associated with spondyloarthritis, and how are they best managed? Therapeutic Advances in Musculoskeletal Disease
Source: Medscape Today Headlines - January 17, 2013 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

GI tract bacteria may protect against autoimmune disease
Early life exposure to normal bacteria of the GI tract (gut microbes) protects against autoimmune disease in mice, according to new research. The study may also have uncovered reasons why females are at greater risk of autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and lupus compared to males.
Source: ScienceDaily Headlines - January 17, 2013 Category: Science Source Type: news

Metal-on-Metal Hip Implants: Use With Caution, FDA SaysMetal-on-Metal Hip Implants: Use With Caution, FDA Says
The agency released extensive guidelines today for problematic, all-metal hip implants that range from selecting the right surgical candidate to determining when to replace the hardware. News Alerts
Source: Medscape Rheumatology Headlines - January 17, 2013 Category: Rheumatology Tags: Orthopaedics News Alert Source Type: news

Mindfulness: Meditation can ease pain from stress-related conditions like IBS and arthritis
People who suffer from painful conditions such as rheumatoid arthritis could ease their symptoms using a form of meditation, say researchers at the University of Wisconsin.
Source: the Mail online | Health - January 17, 2013 Category: Consumer Health News Source Type: news

IVIg for Sjogren's Neuropathy: Worth the Price?IVIg for Sjogren's Neuropathy: Worth the Price?
Could this pricey therapy help treat the neurologic manifestations associated with Sjogren's syndrome? Medscape Rheumatology
Source: Medscape Today Headlines - January 17, 2013 Category: Consumer Health News Tags: Rheumatology Viewpoint Source Type: news

Septic arthritis: Infection can severely damage joint
Septic arthritis — Comprehensive overview covers symptoms and treatment of joint infections.
Source: MayoClinic.com Full Feed - January 17, 2013 Category: Consumer Health News Source Type: news

RCT: Maintenance, reduction, or withdrawal of etanercept after treatment with etanercept and methotrexate in patients with moderate rheumatoid arthritis (PRESERVE)
Source: Lancet Area: News Although moderately active rheumatoid arthritis is common, treatment effects in moderate disease have not been well studied. In addition, the optimum use of biologics requires further investigation, including the use of induction, maintenance, and withdrawal treatment strategies.   The PRESERVE trial in The Lancet compared the efficacy of maintenance, reduction, or withdrawal of etanercept in patients aged between 18 and 70 years with moderately active disease (DAS28 >3.2 and ?5.1) despite treatment with methotrexate (15 to 25 mg every week for at least 8 weeks). In a 36 week open-la...
Source: NeLM - News - January 17, 2013 Category: Drugs & Pharmacology Source Type: news

GI tract bacteria may protect against autoimmune disease
(Helmholtz Association of German Research Centres) Early life exposure to normal bacteria of the GI tract (gut microbes) protects against autoimmune disease in mice, according to research published online in the Jan. 17 edition of Science. The study may also have uncovered reasons why females are at greater risk of autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and lupus compared to males.
Source: EurekAlert! - Medicine and Health - January 17, 2013 Category: Global & Universal Source Type: news

Vitamin D Supplements Fail to Slow Knee OsteoarthritisVitamin D Supplements Fail to Slow Knee Osteoarthritis
Using vitamin D supplements to raise serum 25-hydroxyvitamin D levels had little effect on either progression of knee osteoarthritis pain or cartilage volume loss. Medscape Medical News
Source: Medscape Medical News Headlines - January 16, 2013 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Mindfulness meditation may relieve chronic inflammation
People suffering from chronic inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease and asthma — in which psychological stress plays a major role — may benefit from mindfulness meditation techniques, according to a new study.
Source: ScienceDaily Headlines - January 16, 2013 Category: Science Source Type: news

Denial Of Benefits For Failure To See Specialist Violated ERISA, 6th Circuit Holds
CINCINNATI - A disability plan insurer's denial of benefits to a claimant who indisputably suffered from ankylosing spondylitis (AS) because she failed to consult with a rheumatologist was arbitrary and capricious in violation of the Employee Retirement Income Security Act, the Sixth Circuit U.S. Court of Appeals ruled Dec. 20 in an unpublished opinion, noting that the insurer did not have a specialist conduct an independent medical evaluation (Sandra McCandless v. Standard Insurance Company, No. 11-1308, 6th Cir.; 2012 U.S. App. LEXIS 26235).
Source: LexisNexis® Mealey's™ Disability Insurance Legal News - January 15, 2013 Category: Medical Law Source Type: news

Sexual Healing: Science Proves That Sex is Good for Health
Want to live longer? Make love regularly.read more
Source: Psychology Today Relationships Center - January 15, 2013 Category: Psychiatry & Psychology Authors: Michael Castleman, M.A. Tags: Health Relationships Resilience Sex arthritis foundation arthritis pain body massage chronic pain conditions deep relaxation emotional benefits good sex high blood pressure loving partner marvin gaye massage massage moderate Source Type: news

Rheumatoid arthritis and your heart
Jim Morelli tells us about the risk of heart disease and why it doubles for RA patients.
Source: CNN.com - Health - January 14, 2013 Category: Consumer Health News Source Type: news

Vital Signs: Nutrition: Vitamin D Doesn’t Reduce Knee Pain
A two-year study found that vitamin D, which evidence suggested might slow osteoarthritis, neither reduced knee pain nor restored cartilage.
Source: NYT Health - January 14, 2013 Category: Consumer Health News Authors: By NICHOLAS BAKALAR Tags: Arthritis Body Medicine and Health Knees Vitamin D Featured Vitamins Source Type: news

Abatacept, Adalimumab Equal for RA in Head-to-Head Trial Abatacept, Adalimumab Equal for RA in Head-to-Head Trial
Subcutaneous abatacept and subcutaneous adalimumab were comparably effective when added to background methotrexate for patients with rheumatoid arthritis who had no previous exposure to biologicals. Medscape Medical News
Source: Medscape Today Headlines - January 12, 2013 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Wrong fat in pregnancy diet 'may make kids fatter'
Conclusion This study of 293 mother-child pairs finds that the mother’s blood levels of n-6 PUFA during late pregnancy influence her child’s body fat levels, with higher blood levels equalling higher child fat levels. The researchers say that n-6 PUFA, derived from plant oils are known to have an influence on fat development. Therefore, they say the observed association may suggest ‘prenatal PUFA exposure could be linked to risk of offspring obesity’. However, though this study has merits, including a representative population sample and carrying out detailed assessment of both the mothers and children, it is diffi...
Source: NHS News Feed - January 11, 2013 Category: Consumer Health News Tags: Pregnancy/child Cancer Source Type: news

One patient’s story: From torn ACL to MVP
For kids like 8-year-old Fletcher Gallimore, playing sports is part of their identity. But in September of 2011, Fletcher—who loves football and basketball—was accidentally pushed into a post during football practice, hitting his knee. And the accident took him and his parents down a path they never imagined. The next days followed with occasional pain, but Fletcher and his teammates hoped he’d be OK by Saturday’s game. At practice that week, though, his knee buckled. Concerned, his parents took him to the doctor near their North Carolina hometown, and it became clear that Fletcher wouldn’t be playing on Saturday...
Source: Thrive, Children's Hospital Boston - January 11, 2013 Category: Pediatrics Authors: Andrea Mooney Tags: ACL All posts Sports & exercise ACL tears in young athletes Mininder Kocher orthopedics sports injuries Source Type: news

Latest life-extending cancer drugs 'rationed by postcode': Recommended treatments are handed out in some hospitals but not others
It has also been revealed that many hospitals are failing to prescribe the latest treatments for heart attacks, asthma, multiple sclerosis, arthritis and Crohn's Disease.
Source: the Mail online | Health - January 11, 2013 Category: Consumer Health News Source Type: news

Arthritis Research UK report: Complementary and alternative medicines for the treatment of rheumatoid arthritis, osteoarthritis and fibromyalgia
Source: Arthritis Research UK Area: News Arthritis Research UK has launched its evidence-based report on complementary and alternative medicines for the treatment of rheumatoid arthritis, osteoarthritis and fibromyalgia.   Twenty-five therapies were considered in the report. Each therapy was scored according to their effectiveness on a scale of 1 (little or no evidence that it was effective) to 5 (good evidence that it was effective), based on published data from clinical trials. Effectiveness was measured in terms of improvements in pain, disability or quality of life. In addition the safety of each therapy was ...
Source: NeLM - News - January 10, 2013 Category: Drugs & Pharmacology Source Type: news

Arthritis Drugs May Trigger Shingles (CME/CE)
(MedPage Today) -- Patients with rheumatoid arthritis undergoing treatment with agents such as Enbrel (etanercept), Remicade (infliximab), or Humira (adalimumab) appear to have a significantly increased risk for developing shingles.
Source: MedPage Today Dermatology - January 9, 2013 Category: Dermatology Source Type: news

Prophylaxis, Treatment, and Foods to Avoid in GoutProphylaxis, Treatment, and Foods to Avoid in Gout
Dr. Jonathon Kay on the American College of Rheumatology’s new gout management guidelines. Medscape Rheumatology
Source: Medscape Today Headlines - January 9, 2013 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news