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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 2.

Aspirin and Omega-3 Fatty Acids Combo Fights Inflammation
(Ivanhoe Newswire) -- Experts tout the health benefits of low-dose aspirin and omega-3 fatty acids found in foods like flax seeds and salmon, but the detailed mechanisms involved in their effects are not fully known. Now researchers show that aspirin helps trigger the production of molecules called resolvins that are naturally made by the body from omega-3 fatty acids. These resolvins shut off, or "resolve," the inflammation that underlies destructive conditions such as inflammatory lung disease, heart disease, and arthritis.
Source: Medical Headlines From Ivanhoe.com - February 25, 2013 Category: Consumer Health News Source Type: news

Prevalence of axial SpA in US rheumatology practices: Assessment of ASAS criteria vs. rheumatology expert clinical diagnosis
Conclusion.This is the first systematic epidemiology study of axial SpA using ASAS criteria. Better recognition of axial symptoms is needed, as rheumatologists' expert clinical diagnosesare not always in agreement with ASAS criteria. © 2013 by the American College of Rheumatology
Source: Arthritis Care and Research - February 24, 2013 Category: Rheumatology Authors: Vibeke Strand, Sumati A. Rao, Alicia C Shillington, Mary A. Cifaldi, Michael Mcguire, Eric M. Ruderman Tags: Original Article Source Type: research

Vitamin D deficiency linked to yet another disease: Rheumatoid arthritis
It appears that vitamin D3 undergoes more testing than any other vitamin, even though it isn't a vitamin. It's a hormonal precursor that activates several different metabolic functions throughout the body. Bonding calcium into bone is only one of many others. It's...
Source: NaturalNews.com - February 24, 2013 Category: Consumer Health Advice Source Type: news

Meta-analysis demonstrates association between TLR polymorphisms and rheumatoid arthritis.
Meta-analysis demonstrates association between TLR polymorphisms and rheumatoid arthritis. Genet Mol Res. 2013;12(1):328-34 Authors: Lee YH, Bae SC, Song GG Abstract We investigated whether Toll-like receptor (TLR) polymorphisms confer susceptibility to rheumatoid arthritis and whether they influence clinical characteristics of rheumatoid arthritis. Studies were considered relevant for our meta-analysis if at least two comparisons of an issue were available. Eleven studies with 2078 patients with rheumatoid arthritis and 2581 controls were included, encompassing European and Asian studies. Meta-analysis of ...
Source: Genetics and Molecular Research - February 23, 2013 Category: Genetics & Stem Cells Authors: Lee YH, Bae SC, Song GG Tags: Genet Mol Res Source Type: research

Video: Exercise can help arthritis
A new study suggests that regular exercise can actually help osteoarthritis sufferers and help reduce their pain over time. Dr. Holly Phillips explains.
Source: Health News: CBSNews.com - February 23, 2013 Category: Consumer Health News Source Type: news

In the British countryside, alien species are not always undesirables | Mark Cocker
Our kneejerk suspicion of non-native species reinforces a binary moral vision of natureImagine this autumn scene: you're off to the woods to hunt for a basket of sweet chestnuts. Across the intervening fields where green spikes of barley already break the earth, you flush pheasants and red-legged partridges as you walk. A trio of hares jinks away, their awkward limbs and fantastical ears all dancing on the horizon. Rabbits bolt for cover every 10 paces, and at one particularly fine old sweet chestnut you're caught in the searchlight beam of a little owl's piercing yellow glare.When the bird bounds away it draws your e...
Source: Guardian Unlimited Science - February 23, 2013 Category: Science Authors: Mark Cocker Tags: Comment The Guardian Biodiversity Trees and forests Endangered species Birds Animals UK news Plants Insects Conservation Environment Invasive species Wildlife Comment is free Source Type: news

Early RA Rheumatologist Visit May Cut Need for Surgery Early RA Rheumatologist Visit May Cut Need for Surgery
Patients with RA who see a rheumatologist in the first 3 months after diagnosis are 40% less likely to need orthopaedic surgery in the next 12 years, further highlighting the need for early diagnosis. Medscape Medical News
Source: Medscape Today Headlines - February 22, 2013 Category: Consumer Health News Tags: Rheumatology News Source Type: news

The cure for arthritis? Fish oil and aspirin, according to a breakthrough discovery
Scientists from the Brigham and Women's Hospital and Harvard Medical School in Boston have found that the two work together to combat inflammation.
Source: the Mail online | Health - February 22, 2013 Category: Consumer Health News Source Type: news

Synthetic llama antibodies soothe arthritis pain
A drug based on tiny antibodies originally found in camels and llamas has proved successful in a small clinical trial against arthritis pain
Source: New Scientist - Health - February 22, 2013 Category: Consumer Health News Source Type: research

Want to reduce your Type II diabetes risk? Get some sunshine and up your vitamin D intake
It's amazing how many different meta-analysis papers and epidemiological studies keep popping up associating vitamin D3 with lower disease occurrences for heart disease, breast cancer, rheumatoid arthritis, and Type II or onset adult diabetes. An earlier Japanese...
Source: NaturalNews.com - February 22, 2013 Category: Consumer Health Advice Source Type: news

Rigid occipitocervical fixation: indications, outcomes, and complications in the modern era.
Conclusions Rigid OCF is a safe and effective method of managing occipitocervical instability due to a variety of causes. Outcome measures are favorable, and patients with chronically debilitating diseases such as RA may benefit in terms of improvements in neurological deficit and neck pain. The complication profile is comparable to that reported in other series of OCF in the literature, as well as to the previously used semirigid type of rod/sublaminar wire fixation. PMID: 23432328 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery.Spine - February 22, 2013 Category: Neurosurgery Authors: Bhatia R, Desouza RM, Bull J, Casey AT Tags: J Neurosurg Spine Source Type: research

Sustained beneficial effects of a protocolized treat‐to‐target strategy in very early rheumatoid arthritis: Three year results of the DREAM remission induction cohort
Conclusion:In very early RA, T2T leads to high (sustained) remission rates, improved physical function and health‐related quality of life, and limited radiographic damage after three years in daily clinical practice. © 2013 by the American College of Rheumatology
Source: Arthritis Care and Research - February 22, 2013 Category: Rheumatology Authors: M. Vermeer, H.H. Kuper, H.J. Bernelot Moens, K.W. Drossaers‐Bakker, A.E. van der Bijl, P.L.C.M. van Riel, M.A.F.J. van de Laar Tags: Original Article Source Type: research

Utility of anti‐MDA5 antibody measurement in identifying patients with dermatomyositis and a high risk for developing rapidly progressive interstitial lung disease: A review of the literature and a meta‐analysis
Conclusions.Detection of anti‐MDA5 antibody is a valuable tool for identifying DM patients with a high risk for developing RP‐ILD, but the distribution of classic DM and CADM in patients with this antibody varies among ethnic groups. © 2013 by the American College of Rheumatology
Source: Arthritis Care and Research - February 22, 2013 Category: Rheumatology Authors: Zhiyong Chen, Mengshu Cao, Maria Nieves Plana, Jun Liang, Hourong Cai, Masataka Kuwana, Lingyun Sun Tags: Original Article Source Type: research

Incidence and mortality of obstructive lung disease in rheumatoid arthritis: A population‐based study
Conclusion:Patients with RA are at higher risk of developing OLD, which is significantly associated with premature mortality. Effective diagnostic and therapeutic strategies to detect and manage OLD in patients with RA may help to improve survivorship in these patients. © 2013 by the American College of Rheumatology
Source: Arthritis Care and Research - February 22, 2013 Category: Rheumatology Authors: Carlotta Nannini, Yimy F. Medina‐Velasquez, Sara J. Achenbach, Cynthia S. Crowson, Jay H. Ryu, Robert Vassallo, Sherine E. Gabriel, Eric L. Matteson, Tim Bongartz Tags: Original Article Source Type: research

Risk factors for falls in adults with rheumatoid arthritis: A prospective study
ConclusionsAdults with RA are at high risk of falls. In clinical practice high risk falls patients with RA can be identified by asking whether patients have fallen in the past year. Important risk factors highlighted in this study included: swollen and tender lower limb joints; fatigue and use of psychotropic medicines. © 2013 by the American College of Rheumatology
Source: Arthritis Care and Research - February 22, 2013 Category: Rheumatology Authors: Emma K Stanmore, Jackie Oldham, Dawn A Skelton, Terence O'Neill, Mark Pilling, A John Campbell, Chris Todd Tags: Original Article Source Type: research

Two SLE patients with severe pleurisy: Similar presentations, different causes
Source: Arthritis Care and Research - February 22, 2013 Category: Rheumatology Authors: Caroline M. Gulati, Michael J. Satlin, Cynthia M. Magro, Kyriakos A. Kirou Tags: Clinicopathologic Conference Source Type: research

Kinetic profiles and management of hepatitis B virus reactivation in patients with immune‐mediated inflammatory diseases
ConclusionWe provide new insights into HBV reactivation in patients receiving treatment for IMID. A predefined algorithm may be effective in reducing the risk of HBV reactivation in this population. © 2013 by the American College of Rheumatology
Source: Arthritis Care and Research - February 22, 2013 Category: Rheumatology Authors: Nina Droz, Laurent Gilardin, Patrice Cacoub, Francis Berenbaum, Daniel Wendling, Bertrand Godeau, Anne‐Marie Piette, Emmanuelle Dernis, Mikael Ebbo, Bruno Fautrel, Guillaume Le Guenno, Arsène Mekinian, Brigitte Bernard‐Chabert, Nathalie Costedoat‐C Tags: Original Article Source Type: research

ESSDAI and ESSPRI: EULAR indexes for a complete picture of primary Sjögren's syndrome patients
Conclusions:Alterations of common patient reported outcomes are present in all patients with pSS including those with systemic complications. However, patient's symptoms and systemic complications are 2 different faces of pSS. Therefore, the use of both systemic and patients indexes, such as ESSDAI and ESSPRI, are useful. Since these 2 faces weakly overlap, when designing clinical trials in pSS, one should identify which of both components is the main target of the treatment to test. © 2013 by the American College of Rheumatology
Source: Arthritis Care and Research - February 22, 2013 Category: Rheumatology Authors: R. Seror, J. E. Gottenberg, V. Devauchelle‐Pensec, J. J. Dubost, V. Le Guern, G. Hayem, A.‐L. Fauchais, V. Goeb, E. Hachulla, P. Y. Hatron, C. Larroche, J. Morel, A. Pedriger, X. Puéchal, S. Rist, A. Saraux, D. Sene, J. Sibilia, O. Vittecoq, C. Zarni Tags: Brief Report Source Type: research

Anti‐MDA5‐associated dermatomyositis: Expanding the clinical spectrum
Conclusions:MDA5 autoantibodies are found in DM patients presenting with a symmetric polyarthritis, clinically similar to rheumatoid arthritis. These patients often have features of the antisynthetase syndrome, but in the absence of antisynthetase autoantibodies. Most anti‐MDA5 positive patients had overt clinical myopathy and ILD. The latter, while occasionally severe, typically resolved with immunosuppressive therapy. In this cohort, the MDA5 phenotype is frequently a clinical mimic of the antisynthetase syndrome and is not associated with rapidly progressive ILD. © 2013 by the American College of Rheumatology
Source: Arthritis Care and Research - February 22, 2013 Category: Rheumatology Authors: John C. Hall, Livia Casciola‐Rosen, Lesly‐Ann Samedy, Jessie Werner, Kristie Owoyemi, Sonye K. Danoff, Lisa Christopher‐Stine Tags: Original Article Source Type: research

A systematic review and critical appraisal of validation studies to identify rheumatic diseases in health administrative databases
Conclusion:Methods used in administrative data validation studies of rheumatic diseases are highly variable.Few studies report key measures of diagnostic accuracy, despite their importance for drawing conclusions about the validity of administrative database algorithms. We developeda methodological framework and recommendationsfor validation study conduct and reporting. © 2013 by the American College of Rheumatology
Source: Arthritis Care and Research - February 22, 2013 Category: Rheumatology Authors: Jessica Widdifield BSc, Jeremy Labrecque, Lisa Lix, J. Michael Paterson, Sasha Bernatsky, Karen Tu, Noah Ivers, Claire Bombardier Tags: Original Article Source Type: research

Giant coronary artery aneurysms and Churg‐Strauss syndrome
Source: Arthritis and Rheumatism - February 22, 2013 Category: Rheumatology Authors: Patrik Htun, Marius Horger, Meinrad Gawaz, Suzanne Fateh‐Moghadam Tags: Clinical Image Source Type: research

Transcriptomics of wild type and mice lacking ADAMTS‐5 activity identifies genes involved in osteoarthritis initiation and cartilage destruction
Conclusion:This work provides new insights into the sequence of gene dysregulation and molecular basis of cartilage destruction in OA. © 2013 American College of Rheumatology.
Source: Arthritis and Rheumatism - February 22, 2013 Category: Rheumatology Authors: John F. Bateman, Lynn Rowley, Daniele Belluoccio, Ben Chan, Katrina Bell, Amanda J. Fosang, Christopher B. Little Tags: Full Length Source Type: research

Inhibition of connective tissue growth factor ameliorates rheumatoid arthritis in a murine model
Conclusions): The present study showed that blockade of CTGF prevented progression of arthritis in CIA mice. Anti‐CTGF mAb treatment suppressed the pathological T cells function and restored aberrant osteoclastogenesis in CIA mice. CTGF may become a new therapeutic target for treatment of RA. © 2013 American College of Rheumatology.
Source: Arthritis and Rheumatism - February 22, 2013 Category: Rheumatology Authors: Kazuhisa Nozawa, Maki Fujishiro, Mikiko Kawasaki, Ayako Yamaguchi, Keigo Ikeda, Shinji Morimoto, Kazuhisa Iwabuchi, Mitsuaki Yanagida, Shouzo Ichinose, Megumi Morioka, Hideoki Ogawa, Kenji Takamori, Yoshinari Takasaki, Iwao Sekigawa Tags: Full Length Source Type: research

Reply to Geradi and colleagues regarding RA‐related autoantibodies and lung disease
Source: Arthritis and Rheumatism - February 22, 2013 Category: Rheumatology Authors: M. Kristen Demoruelle, Kevin D. Deane Tags: Reply to Letter to the Editor Source Type: research

Frequency of antibodies to mutated‐citrullinated vimentin in chronic obstructive pulmonary disease: Comment on the article by Demoruelle et al.
Source: Arthritis and Rheumatism - February 22, 2013 Category: Rheumatology Authors: Maria Chiara Gerardi, Nicoletta De Luca, Cristiano Alessandri, Cristina Iannuccelli, Guido Valesini, Manuela Di Franco Tags: Letter to the Editor Source Type: research

In vivo cyclic compression causes cartilage degeneration and subchondral bone changes in mouse tibiae
Conclusion:This non‐invasive loading model permits dissection of temporal and topographical changes in cartilage and bone and will enable investigation of the efficacy of treatment interventions targeting joint biomechanics or biological events that promote OA onset and progression. © 2013 American College of Rheumatology.
Source: Arthritis and Rheumatism - February 22, 2013 Category: Rheumatology Authors: Frank C. Ko, Cecilia Dragomir, Darren A. Plumb, Steven R. Goldring, Timothy M. Wright, Mary B. Goldring, Marjolein C.H. van der Meulen Tags: Full Length Source Type: research

CD109 overexpression ameliorates skin fibrosis in a bleomycin‐induced mouse model of scleroderma
Conclusion:Our findings suggest that CD109 inhibits TGF‐ß signaling and fibrotic responses in experimental murine scleroderma, and reveal CD109 as a potential molecular target for therapeutic intervention in scleroderma. © 2013 American College of Rheumatology.
Source: Arthritis and Rheumatism - February 22, 2013 Category: Rheumatology Authors: Joshua Vorstenbosch, Hasan Al‐Ajmi, Sebastian Winocour, Alissa Trzeciak, Lucie Lessard, Anie Philip Tags: Brief Report Source Type: research

Muscle strength, physical fitness and well-being in children and adolescents with juvenile idiopathic arthritis and the effect of an exercise programme: a randomized controlled trial
Conclusions: A weight bearing exercise programme, with muscle strength training with free weights and rope skipping was well tolerated without negative consequences on pain. It also improved muscle strength in the legs and can be recommended for children and adolescents with JIA.
Source: Pediatric Rheumatology - February 22, 2013 Category: Rheumatology Authors: Eva SandstedtAnders FasthMeta EekEva Beckung Source Type: research

Periodic knee injections of collagen tripeptide delay cartilage degeneration in rabbit experimental osteoarthritis
Conclusion: Periodical injections of Ctp and Ctp/HA delayed progression of cartilage degeneration of early osteoarthritis induced by ACLT in rabbits. This effect appears to be exerted by promotion of type II collagen synthesis predominantly.
Source: Arthritis Research and Therapy - February 22, 2013 Category: Rheumatology Authors: Takuya NaraokaYasuyuki IshibashiEiichi TsudaYuji YamamotoTomomi KusumiSatoshi Toh Source Type: research

Behcet's disease in India: A dermatological perspective
Conclusion: The disease occurs in a much milder form in India and is primarily mucocutaneous and arthritic. A high index of suspicion in patients with MC lesions may result in early diagnosis, management and prevention of complications of BD. We suggest colchicine as an effective and safe therapeutic option for MC and joint involvement.
Source: Indian Journal of Dermatology, Venereology and Leprology - February 22, 2013 Category: Dermatology Authors: Archana SingalNamrata ChhabraDeepika PandhiJolly Rohatgi Source Type: research

Author Reply: Hip Resurfacing Arthroplasty in Inflammatory Arthritis
We appreciate Dr Vaishya's interest in our article. The first concern was the reliability of dual-energy x-ray absorptiometry (DEXA) in the presence of “osteoblastic activity” in the periarticular bone. The reference quoted, namely, the work of Orwoll et al. , was about the effect of osteophytic calcifications (not osteoblastic activity as mentioned in Dr Vaishya's letter) on bone mineral density measurements. Orwoll et al. clearly mention that while osteophytes affected bone density measurements in the spine, osteophytes did not affect bone density measurements at any femoral site in their study. This observation has...
Source: The Journal of Arthroplasty - February 21, 2013 Category: Orthopaedics Authors: Rajesh Malhotra Tags: Letters to the Editor Source Type: research

CD154: the atherosclerotic risk factor in rheumatoid arthritis?
Atherosclerosis, now regarded as a chronic inflammatory disease of the arterial wall, and its clinical manifestations have increasingly been associated with rheumatoid arthritis (RA), supporting the notion that autoimmune diseases and vascular disorders share common etiological features. Indeed, evidence pertaining to this matter indicates that inflammation and its multiple components are the driving force behind the pathogenesis of these disorders. Interestingly, CD154 and its receptors have emerged as major players in the development of RA and atherosclerosis, which raises the possibility that this axis may represent an ...
Source: BioMed Central - February 21, 2013 Category: Journals (General) Authors: Ghada S HassanDaniel YacoubNada AlaaeddineAmal NadiriYahye MerhiWalid Mourad Source Type: research

A Successful Disease-Modifying Agent for Osteoarthritis?A Successful Disease-Modifying Agent for Osteoarthritis?
The effect on radiologic progression and pain of knee osteoarthritis is examined in this double-blind, placebo-controlled study. Medscape Rheumatology
Source: Medscape Today Headlines - February 21, 2013 Category: Consumer Health News Tags: Rheumatology Viewpoint Source Type: news

Video: Arthritis misconceptions: Separating fact, fiction
Despite how common arthritis is, there are many misconceptions about the leading cause of disability in this country. Dr. Holly Phillips talks to Charlie Rose and Norah O'Donnell about the facts of the condition.
Source: Health News: CBSNews.com - February 21, 2013 Category: Consumer Health News Source Type: news

Excitatory amino acids display compartmental disparity between plasma and synovial fluid in clinical arthropathies.
CONCLUSIONS: Clinical samples demonstrated distinct, independent compartmental EAA concentrations between blood and joint compartments in support that local arthritic processes rather than plasma influence SF EAA concentrations. The SF EAA levels, whether from local cell production, local neurogenic sources, and/or transport-gradient mechanisms, parallel local pathology in the joint compartment and thus serve as surrogate biomarkers of local inflammatory processes. PMID: 23413050 [PubMed - in process]
Source: International Journal of Clinical and Experimental Pathology - February 21, 2013 Category: Pathology Authors: McNearney TA, Westlund KN Tags: Int J Clin Exp Pathol Source Type: research

Postoperative Septic Arthritis After Elective Equine Arthroscopy Without Antimicrobial Prophylaxis
ConclusionsJoint infection rate in the horse population that had elective arthroscopy without antimicrobial prophylaxis compares favorably with other reports citing 0.9% sepsis in horses after arthroscopy in which horses received either no antimicrobials or were administered pre or perioperative antimicrobial therapy.
Source: Veterinary Surgery - February 21, 2013 Category: Veterinary Research Authors: Hanna Borg, James L. Carmalt Tags: Original Article: Clinical Source Type: research

Choosing wisely: The American College of Rheumatology's top 5 list of things physicians and patients should question
ConclusionThe ACR Top 5 list is intended to promote discussions between physicians and patients about health care practices in rheumatology whose use should be questioned and to assist rheumatologists in providing high‐value care.
Source: Arthritis Care and Research - February 21, 2013 Category: Rheumatology Authors: Jinoos Yazdany, Gabriela Schmajuk, Mark Robbins, David Daikh, Ashley Beall, Edward Yelin, Jennifer Barton, Adam Carlson, Mary Margaretten, JoAnn Zell, Lianne S. Gensler, Victoria Kelly, Kenneth Saag, Charles King, Tags: Special Article Source Type: research

Applications submitted to extend marketing authorisation for certolizumab pegol (Cimzia®) to include treatment of active psoriatic arthritis and active axial spondyloarthritis
Source: PR Newswire Area: News UCB has announced new regulatory filings with the European Medicines Agency (EMA) and the FDA to extend the marketing authorisation for certolizumab pegol (Cimzia®) for the treatment of adult patients with active psoriatic arthritis (PsA) and for adult patients with active axial spondyloarthritis (axSpA). Certolizumab pegol is a Fc-free, PEGylated anti-TNF. In the EU, it is currently licensed in combination with methotrexate (MTX) for the treatment of moderate to severe active rheumatoid arthritis in adult patients inadequately responsive to disease-modifying anti-rheumatic drugs...
Source: NeLM - News - February 21, 2013 Category: Drugs & Pharmacology Source Type: news

MHRA warns of excessive heavy metal content of some unlicensed Chinese medicines purchased online
Source: MHRA Area: News The MHRA has warned people not to buy or use potentially dangerous unlicensed Chinese medicines sold online after some products were found to contain excessive levels of mercury or lead. Health authorities in Hong Kong told the MHRA that various products are being recalled and they should not be used by people in the UK because of an increased toxic poisoning risk. The products are: . Bak Foong Pills - used to relieve menstrual discomfort; . Fung Shing Paij Tian-Ma Wan - used to relieve arthritis and headaches; and . Shi Hu Ye Guang Wan and Nai Chang Ming ...
Source: NeLM - News - February 21, 2013 Category: Drugs & Pharmacology Source Type: news

The role of the circadian clock in rheumatoid arthritis
Rheumatoid arthritis exhibits diurnal variation in symptoms, with patients suffering with increased painful joint stiffness in the early morning. This correlates with an early morning rise in circulating levels of pro-inflammatory cytokines, such as interleukin-6. This temporal variation in disease pathology is directed by the circadian clock, both at a systemic level, through signalling pathways derived in the central clock, and at a local level by autonomous clocks found within inflammatory organs and cells. Indeed many cellular components of the immune system, which are involved in the pathogenesis of rheumatoid arthri...
Source: Arthritis Research and Therapy - February 20, 2013 Category: Rheumatology Authors: Julie GibbsDavid Ray Source Type: research

Follow the Bouncing Ball: A Patient CaseFollow the Bouncing Ball: A Patient Case
In this Rheumatology Curbside Consult, Dr. Stephen Paget presents an intriguing case of a 75-year-old man with fatigue, elevated sedimentation rate, and blurred vision. Medscape Rheumatology
Source: Medscape Today Headlines - February 20, 2013 Category: Consumer Health News Tags: Rheumatology Clinical Case Source Type: news

Important Evidence Supporting Fibromyalgia As A Spectrum Disorder
Researchers have determined that fibromyalgia prevalence is 2.1% of the general population in Germany. Results appearing in Arthritis Care & Research, a journal published by Wiley on behalf of the American College of Rheumatology (ACR), suggest that fibromyalgia is a spectrum disorder rather than a categorical illness. Additionally, a number of fibromyalgia cases in the general population satisfy proposed criteria for physical symptom disorder - the presence of one or more physical symptoms that impair function, which cannot be explained by another clinical or psychiatric illness...
Source: Health News from Medical News Today - February 20, 2013 Category: Consumer Health News Tags: Fibromyalgia Source Type: news

The effectiveness of Echinacea extract or composite glucosamine, chondroitin and methyl sulfonyl methane supplements on acute and chronic rheumatoid arthritis rat model
The study aimed to investigate the effect of the oral administration for 15 days of either Echinacea (E) or genuphil (a composite of chondroitin sulphate, glucosamine and methyl sulfonyl methane [GCM]) nutraceutical supplements on female rat model of acute or chronic arthritis induced by bacterial outer membrane protein (OMP) from faecal flora of healthy and rheumatic humans. Anti-cyclic citrullinated peptide (anti-CCP2), C-reactive protein (CRP) and rheumatoid factor (RF) values increased (p < 0.05) in both arthritic groups as compared to normal values. The rheumatic markers anti-CCP2, CRP and RF values decre...
Source: Toxicology and Industrial Health current issue - February 20, 2013 Category: Toxicology Authors: Arafa, N. M., Hamuda, H. M., Melek, S. T., Darwish, S. K. Tags: Articles Source Type: research

Depression and systemic lupus erythematosus: a systematic review.
ConclusionsDifferences in assessment techniques appear to be the main explanation for the variability in findings and important methodological limitations are present in the available literature to definitively point to the prevalence of depression, type of depression and most prevalent symptoms. To date, the relationship between depression and SLE disease activity also appears controversial. Methodological limitations are present in the available literature and it would be necessary to develop evidence-based guidelines to improve the diagnosis of depression in SLE. Identification of SLE-specific biomarkers of depression a...
Source: Lupus - February 20, 2013 Category: Rheumatology Authors: Palagini L, Mosca M, Tani C, Gemignani A, Mauri M, Bombardieri S Tags: Lupus Source Type: research

Relationship between iron metabolism, oxidative stress, and insulin resistance in patients with systemic lupus erythematosus.
Conclusions: This study found that oxidative stress was higher in the group of SLE patients with IR, and increased ferritin, whether caused by the inflammatory process per se or hyperinsulinaemia, can favour the redox process. In addition, the preset data reinforce the need to measure oxidative stress with several methodologies with different assumptions. PMID: 23424997 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Rheumatology - February 20, 2013 Category: Rheumatology Authors: Lozovoy M, Simão A, Oliveira S, Iryioda T, Panis C, Cecchini R, Dichi I Tags: Scand J Rheumatol Source Type: research

Normal inflammasome activation and low production of IL-23 by monocyte-derived macrophages from subjects with a history of reactive arthritis.
Conclusions: PBMNs and macrophages from healthy subjects with previous ReA show normal inflammasome activation and low TNF-α and IL-23 production. This low cytokine production may impair bacterial elimination and thereby contribute to the triggering of ReA. PMID: 23425136 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Rheumatology - February 20, 2013 Category: Rheumatology Authors: Välimäki E, Aittomäki S, Karenko L, Kantonen J, Pettersson T, Turunen U, Matikainen S, Leirisalo-Repo M, Repo H Tags: Scand J Rheumatol Source Type: research

Comparison of methodologies for analysing the progression of joint destruction in rheumatoid arthritis.
Conclusions: A multivariate normal regression model on subsequent radiographs is a powerful and robust method for analysing longitudinal joint destruction data. PMID: 23425151 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Rheumatology - February 20, 2013 Category: Rheumatology Authors: Knevel R, Tsonaka R, Cessie SL, Linden MV, Huizinga T, Heijde DV, Houwing-Duistermaat J, Mil AV Tags: Scand J Rheumatol Source Type: research

Heart rate variability in fibromyalgia patients and healthy controls during non-REM and REM sleep: a case-control study.
Conclusions: RMSSD, indicative of parasympathetic predominance, is attenuated in FM patients compared to HCs during N2 sleep and REM sleep. This difference was not present for the HF component. HRV during sleep in FM patients is moderately and positively associated with sleep quality and moderately and negatively associated with neck/shoulder pain. PMID: 23425526 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Rheumatology - February 20, 2013 Category: Rheumatology Authors: Mork P, Nilsson J, Lorås H, Riva R, Lundberg U, Westgaard R Tags: Scand J Rheumatol Source Type: research

IL-17-mediated Bcl-2 expression regulates survival of fibroblast like synoviocytes in rheumatoid arthritis through STAT3 activation
Conclusions: Our data demonstrate that STAT3 is critical in IL-17-induced survival of FLS from RA patients. Therefore, therapeutic strategies that target the IL-17/STAT3 pathway might be strong candidates for RA treatment modalities.
Source: BioMed Central - February 20, 2013 Category: Journals (General) Authors: Seon-Yeong LeeSeung-Ki KwokHye-Jin SonJun-Geol RyuEun-Kyung KimHye-Jwa OhMi-La ChoJi Hyeon JuSung-Hwan ParkHo-Youn Kim Source Type: research

ACETAMINOPHEN - APAP ARTHRITIS (Acetaminophen) Tablet, Film Coated, Extended Release [Valu Merchandisers Company]
Updated Date: Feb 20, 2013 EST
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - February 20, 2013 Category: Drugs & Pharmacology Source Type: news