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Lineage IdentityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Segregation of endoderm and mesoderm lineages is a fundamental event in early embryogenesis. Using sea urchin embryos, Sethi et al. (p. 590) found that Notch and canonical Wnt pathways crosstalk … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Natural ResistanceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Avermectins are the most widely used class of anthelmintic drugs, both as pesticides and as treatments for nematode-borne diseases, with the evolution of resistance presenting a major global health and … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Nature or Drug Abuse?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There are significant structural changes in striatal and prefrontal brain regions of stimulant drugdependent individuals. However, it is not clear if these brain abnormalities predate drug-taking, rendering individuals vulnerable for … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Immune SentinelsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A classic paradigm in immunology holds that the immune response occurs in two waves: Rapidly responding cells of the innate immune system help to contain the invading pathogen and alert … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Heat or Acid?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The question of how tropical coral reefs will respond to increasing atmospheric greenhouse gas concentrations and concomitant climate change is widely debated. Model predictions and laboratory experiments suggest that decreasing … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Mystery of an Unextreme MicrobeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Metagenomics has given us glimpses into the huge diversity of microorganisms that are the engines of Earth's elemental cycling. These kinds of surveys can supply a good idea of the … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Girl PowerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The potential of affirmative action policies to reduce overall outcomes because of lower individual performance has been discussed widely and at length. But do quotas or preferential treatment of applicants … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

An Iron Hand for SiliconEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Carbon-silicon bonds are integral to the structure of the silicone materials widely used in adhesives, cosmetics, and numerous other industrial and consumer products. Generally, platinum-based catalysts have performed best in … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Monsoon ForcingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dansgaard/Oeschger (D/O) events—the sudden, millennial-scale periods of warmth that punctuate the cold climate of the Last Glacial period, and Heinrich events—cold intervals characterized by tremendous discharges of icebergs into the … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Probing Pulsar RotationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pulsars are strongly magnetized, rapidly rotating neutron stars. Those with periods of the order of milliseconds obtain their fast spin by accreting mass from a companion star in a binary … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Nailing Down the Superfluid TransitionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A gas of fermions, the class of particle that protons, neutrons, and electrons belong to, can be found in contexts as different as neutron stars and a block of metal. … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Monitoring MeiosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
During meiosis, or in yeast sporulation, haploid cells are generated from diploid cells. Brar et al. (p. 552, published online 22 December) performed a detailed analysis of messenger RNA (mRNA) … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Education: Science IllustratedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
U.S. college freshmen aspiring to a career in science often lose their enthusiasm. One cause may be introductory courses lacking an integration of the scientific process. If textbooks emphasized the … [Read more] (Source: Editors' Choice)
Source: Editors' Choice - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Chemistry: Sacrifices at the SurfaceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There has been a thriving research discussion over the past decade about the tendency of certain dissolved ions to accumulate at the air/water interface of aerosols, and the associated implications … [Read more] (Source: Editors' Choice)
Source: Editors' Choice - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Cell Biology: Push Me Pull YouEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A contractile ring composed of actin and myosin promotes cytokinesis—the final stage of cell division when daughter cells are physically separated from one another. The small GTPase RhoA regulates the … [Read more] (Source: Editors' Choice)
Source: Editors' Choice - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Climate Science: Here's Looking at YouEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Permafrost contains huge amounts of organic carbon. If it were to thaw in response to climate warming, it would constitute a very large potential source of methane, a powerful greenhouse … [Read more] (Source: Editors' Choice)
Source: Editors' Choice - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Genetics: Wrapped Up RightEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
All eukaryotic chromosomes have a centromere, which ensures that the genomic DNA is shared equally between daughter cells during cell division. Centromeres are defined by the presence of nucleosomes that … [Read more] (Source: Editors' Choice)
Source: Editors' Choice - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

Sociology: I Liked You From the StartEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There is a tendency for people involved in a particular social network to be similar, but separating cause and effect can be difficult. To study the evolution of networks and … [Read more] (Source: Editors' Choice)
Source: Editors' Choice - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

[Podcast] Science PodcastEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The show includes how corals respond to climate change, inherited factors for drug addiction, 2011 Visualization Challenge winners, and more. (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

New ProductsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers. (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

[Report] Abnormal Brain Structure Implicated in Stimulant Drug AddictionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A neurological marker of addiction vulnerability occurs in sibling pairs who do not take drugs.Authors: Karen D. Ersche, P. Simon Jones, Guy B. Williams, Abigail J Turton, Trevor W. Robbins, Edward T. Bullmore (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Karen D. Ersche Source Type: research

[Report] Innate Response Activator B Cells Protect Against Microbial SepsisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A specialized population of B lymphocytes is important for controlling bacterial infections and preventing sepsis.Authors: Philipp J. Rauch, Aleksey Chudnovskiy, Clinton S. Robbins, Georg F. Weber, Martin Etzrodt, Ingo Hilgendorf, Elizabeth Tiglao, Jose-Luiz Figueiredo, Yoshiko Iwamoto, Igor Theurl, Rostic Gorbatov, Michael T. Waring, Adam T. Chicoine, Majd Mouded, Mikael J. Pittet, Matthias Nahrendorf, Ralph Weissleder, Filip K. Swirski (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Philipp J. Rauch Source Type: research

[Report] Growth of Western Australian Corals in the AnthropoceneEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cores taken from massive corals indicate that temperature rather than ocean acidification has governed reef growth.Authors: Timothy F. Cooper, Rebecca A. O'Leary, Janice M. Lough (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Timothy F. Cooper Source Type: research

[Report] Sequential Signaling Crosstalk Regulates Endomesoderm Segregation in Sea Urchin EmbryosEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Separation of deuterostome endoderm and mesoderm occurs through sequential interactions between Notch and Wnt signaling.Authors: Aditya J. Sethi, Radhika M. Wikramanayake, Robert C. Angerer, Ryan C. Range, Lynne M. Angerer (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Aditya J. Sethi Source Type: research

[Report] Untangling Genomes from Metagenomes: Revealing an Uncultured Class of Marine EuryarchaeotaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Reconstruction of whole genomes from a complex microbial community has revealed an evolutionary surprise.Authors: Vaughn Iverson, Robert M. Morris, Christian D. Frazar, Chris T. Berthiaume, Rhonda L. Morales, E. Virginia Armbrust (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Vaughn Iverson Source Type: research

[Report] Female Leadership Raises Aspirations and Educational Attainment for Girls: A Policy Experiment in IndiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The effects of female leaders on girls occur via policy changes in the short run and parental aspirations in the longer run.Authors: Lori Beaman, Esther Duflo, Rohini Pande, Petia Topalova (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Lori Beaman Source Type: research

[Report] Affirmative Action Policies Promote Women and Do Not Harm Efficiency in the LaboratoryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Increasing the representation of competition-averse individuals does not alter overall output.Authors: Loukas Balafoutas, Matthias Sutter (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Loukas Balafoutas Source Type: research

[Report] Natural Variation in a Chloride Channel Subunit Confers Avermectin Resistance in C. elegansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Resistance to avermectin, an anti-nematode drug, is conferred by a deletion in a glutamate-gated chloride channel.Authors: Rajarshi Ghosh, Erik C. Andersen, Joshua A. Shapiro, Justin P. Gerke, Leonid Kruglyak (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Rajarshi Ghosh Source Type: research

[Report] High-Latitude Forcing of the South American Summer Monsoon During the Last GlacialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
High-latitude processes in the Northern and Southern Hemispheres both influence the South American Summer Monsoon.Authors: Lisa C. Kanner, Stephen J. Burns, Hai Cheng, R. Lawrence Edwards (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Lisa C. Kanner Source Type: research

[Report] Iron Catalysts for Selective Anti-Markovnikov Alkene Hydrosilylation Using Tertiary SilanesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Iron catalysts offer a potentially cheaper route than platinum for certain commercially useful carbon-silicon compounds.Authors: Aaron M. Tondreau, Crisita Carmen Hojilla Atienza, Keith J. Weller, Susan A. Nye, Kenrick M. Lewis, Johannes G. P. Delis, Paul J. Chirik (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Aaron M. Tondreau Source Type: research

[Report] Revealing the Superfluid Lambda Transition in the Universal Thermodynamics of a Unitary Fermi GasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Thermodynamic quantities for the superfluid transition of a strongly interacting atomic Fermi gas were measured.Authors: Mark J. H. Ku, Ariel T. Sommer, Lawrence W. Cheuk, Martin W. Zwierlein (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Mark J. H. Ku Source Type: research

[Report] Spin-Down of Radio Millisecond Pulsars at GenesisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Numerical calculations show that processes responsible for spinning up millisecond pulsars may also lead them to slow down.Author: Thomas M. Tauris (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Thomas M. Tauris Source Type: research

[Research Article] The Southern Ocean’s Role in Carbon Exchange During the Last DeglaciationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Radiocarbon measurements of deep-sea corals reveal the presence of old, carbon-rich water in the Southern Ocean.Authors: Andrea Burke, Laura F. Robinson (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Andrea Burke Source Type: research

[Research Article] High-Resolution View of the Yeast Meiotic Program Revealed by Ribosome ProfilingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
During yeast sporulation, the production of most proteins is tightly regulated by both messenger RNA levels and translational control.Authors: Gloria A. Brar, Moran Yassour, Nir Friedman, Aviv Regev, Nicholas T. Ingolia, Jonathan S. Weissman (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Gloria A. Brar Source Type: research

[Brevia] Nanoscopy in a Living Mouse BrainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Super high-resolution microscopy resolves neuron dynamics in the cerebral cortex of a living mouse.Authors: Sebastian Berning, Katrin I. Willig, Heinz Steffens, Payam Dibaj, Stefan W. Hell (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Sebastian Berning Source Type: research

[Perspective] Physics: Seeing the Superfluid Transition of a GasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The universal thermodynamic functions of a superfluid formed from a fermion gas of strongly interacting lithium atoms have been measured precisely.Author: Wilhelm Zwerger (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Wilhelm Zwerger Source Type: research

[Perspective] Climate Change: Marching in Near Lock-StepEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A cave record from Peru closely matches climate patterns seen in cores from Greenland and the North Atlantic Ocean.Author: Donald T. Rodbell (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Donald T. Rodbell Source Type: research

[Perspective] Neuroscience: To Stop or Not to Stop?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Does chronic drug abuse cause brain abnormalities, or do they develop before the onset of dependence?Authors: Nora D. Volkow, Ruben D. Baler (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Nora D. Volkow Source Type: research

[Perspective] Evolution: Surviving in a Toxic WorldEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Natural variations in a single gene of wild C. elegans populations confer resistance to the bacterial toxin avermectin.Author: Adrian J. Wolstenholme (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Adrian J. Wolstenholme Source Type: research

[Perspective] Economics: Ready, Steady, CompeteEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Women's willingness to compete can be increased through appropriate affirmative action.Author: Marie Claire Villeval (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Marie Claire Villeval Source Type: research

[Policy Forum] Scientific Publications: Coercive Citation in Academic PublishingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Many journal editors appear to strategically target authors and papers to pressure them into citing the editors' journals.Authors: Allen W. Wilhite, Eric A. Fong (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Allen W. Wilhite Source Type: research

[Books et al.] Books ReceivedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A listing of books received at Science during the week ending 27 January 2012. (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

[Book Review] When Do Incentives Corrupt?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Analyzing incentives in terms of power rather than as trades, Grant concludes that their use to further desired social and political goals raises some ethical concerns.Author: Tyler Cowen (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Tyler Cowen Source Type: research

[Book Review] Have We “Met the Enemy”?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Guillemin describes the aftermath of and investigation into the fall 2001 anthrax letters.Author: David A. Relman (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: David A. Relman Source Type: research

[Letter] Proceed with Planning Despite Multiple ModelsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Author: Robert Dickinson (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Robert Dickinson Source Type: research

[Technical Response] Response to Comment on “Abiotic Pyrite Formation Produces a Large Fe Isotope Fractionation”Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: Romain Guilbaud, Ian B. Butler, Rob M. Ellam (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Romain Guilbaud Source Type: research

[Technical Comment] Comment on “Abiotic Pyrite Formation Produces a Large Fe Isotope Fractionation”Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: Andrew D. Czaja, Clark M. Johnson, Kosei E. Yamaguchi, Brian L. Beard (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Andrew D. Czaja Source Type: research

[Correction] Corrections and ClarificationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research

[Letter] Invasive Species Unchecked by Climate—ResponseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: Michael T. Burrows, David S. Schoeman, Carlos M. Duarte, Mary I. O'Connor, Lauren B. Buckley, Carrie V. Kappel, Camille Parmesan, Benjamin S. Halpern, Chris Brown, Keith M. Brander, John F. Bruno, John M. Pandolfi, William J. Sydeman, Pippa Moore, Wolfgang Kiessling, Anthony J. Richardson, Elvira S. Poloczanska (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Michael T. Burrows Source Type: research

[Letter] Invasive Species Unchecked by ClimateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Author: Philip E. Hulme (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Philip E. Hulme Source Type: research