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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 15.

Evaluation of the Psychoeducation Given to the Elderly at Nursing Homes for a Healthy Lifestyle and Developing Life Satisfaction.
Abstract The research was carried out as a pre-test, post-test patterned intervention with one group in order to evaluate the psychoeducation given to older people at nursing homes for a healthy lifestyle and developing life satisfaction. The research was done with 21 female and 21 male older people staying at the state-owned Seyran Bağlari Nursing Home/Elderly Caring Rehabilitation Center and the Ümitköy Nursing Home. In the psychoeducation program, each session was conducted for a duration of 60-90 min in the nursing homes' education classrooms. After the psychoeducation program, the life satisfaction index, ...
Source: Community Mental Health Journal - February 12, 2013 Category: Psychiatry Authors: Tambağ H, Oz F Tags: Community Ment Health J Source Type: research

Initial results of an optimized perfusion system.
CONCLUSION: With the described optimized perfusion system, a significantly lower priming volume, leading to less hemodilution after the onset of CPB, was achieved. The amount of blood transfusions and the inflammatory response were reduced. PMID: 23404056 [PubMed - as supplied by publisher]
Source: Perfusion - February 12, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Starck C, Bettex D, Felix C, Reser D, Dreizler T, Hasenclever P, Falk V Tags: Perfusion Source Type: research

A cluster-based factor rotation.
Abstract A new oblique factor rotation method is proposed, the aim of which is to identify a simple and well-clustered structure in a factor loading matrix. A criterion consisting of the complexity of a factor loading matrix and a between-cluster dissimilarity is optimized using the gradient projection algorithm and the k-means algorithm. It is shown that if there is an oblique rotation of an initial loading matrix that has a perfect simple structure, then the proposed method with Kaiser's normalization will produce the perfect simple structure. Although many rotation methods can also recover a perfect simple struc...
Source: The British Journal of Mathematical and Statistical Psychology - February 12, 2013 Category: Statistics Authors: Yamamoto M, Jennrich RI Tags: Br J Math Stat Psychol Source Type: research

Mesenchymal stem cells from amnion and amniotic fluid in bovine.
This study contributes to reinforce the emerging importance of these cells as ideal tools in veterinary medicine. A deeper evaluation of the immunological properties needs to be performed in order to better understand their role in cellular therapy. PMID: 23404849 [PubMed - as supplied by publisher]
Source: Reproduction - February 12, 2013 Category: Reproduction Medicine Authors: Corradetti B, Meucci A, Bizzaro D, Cremonesi F, Lange-Consiglio A Tags: Reproduction Source Type: research

Prediction of embryo implantation potential by mass spectrometry fingerprinting of the culture medium.
This study has evaluated the performance of a multivariate statistical model to predict embryo implantation potential by processing data from the chemical fingerprinting of culture medium samples used for human embryo culture. The culture medium harvested of 113 embryos from 55 patients undergoing intracytoplasmic sperm injection was collected after embryo transfer. The samples were split into positive (n=29) and negative (n=84) implantation groups according their implantation outcomes (100% or 0% of implantation). The samples were individually diluted and analyzed by electrospray Ionization mass spectrometry (ESI-MS). The...
Source: Reproduction - February 12, 2013 Category: Reproduction Medicine Authors: Cortezzi SS, Cabral EC, Trevisan MG, Ferreira CR, Setti AS, Braga DP, Figueira RD, Iaconelli A, Eberlin MN, Borges E Tags: Reproduction Source Type: research

Purinergic signalling during sterile liver injury
Abstract The liver plays a vital role in the organism, and thousands of patients suffer and even die from hepatic complications every year. Viral hepatitis is one of the most important causes of liver‐related pathological processes. However, sterile liver diseases, such as drug‐induced liver injury, cirrhosis and fibrosis, are still a worldwide concern and contribute significantly to liver transplantation statistics. During hepatocyte death, several genuine intracellular contents are released to the interstitium, where they will trigger inflammatory responses that may boost organ injury. Intracellular purines are key m...
Source: Liver International - February 12, 2013 Category: Gastroenterology Authors: André G. Oliveira, Pedro E. Marques, Sylvia S. Amaral, Jayane L. D. Quintão, Bruno Cogliati, Maria L. Z. Dagli, Vera Rogiers, Tamara Vanhaecke, Mathieu Vinken, Gustavo B. Menezes Tags: Review Article Source Type: research

Association of Shiga toxin glycosphingolipid receptors with membrane microdomains of toxin-sensitive lymphoid and myeloid cells [Research Articles]
Glycosphingolipids (GSLs) of the globo-series constitute specific receptors for Shiga toxins (Stxs) released by certain types of pathogenic Escherichia coli strains. Stx-loaded leukocytes may act as transporter cells in the blood and transfer the toxin to endothelial target cells. Therefore, we performed a thorough investigation on the expression of globo-series GSLs in serum-free cultivated Raji and Jurkat cells, representing B- and T-lymphocyte descendants, respectively, as well as THP-1 and HL-60 cells of the monocyte and granulocyte lineage, respectively. The presence of Stx-receptors in GSL preparations of Raji and TH...
Source: The Journal of Lipid Research - February 12, 2013 Category: Lipidology Authors: Kouzel, I. U., Pohlentz, G., Storck, W., Radamm, L., Hoffmann, P., Bielaszewska, M., Bauwens, A., Cichon, C., Schmidt, M. A., Mormann, M., Karch, H., Muthing, J. Tags: Research Articles Source Type: research

Assessment of the variation in American Society of Anaesthesiologists Physical Status Classification assignment in small animal anaesthesia
Conclusions and clinical relevanceThis study suggests major discrepancies can occur between observers given identical information when using the ASA‐PSC to categorise health status in compromised small animal patients. The significant potential for interobserver variability in classification allocation should be borne in mind when the ASA‐PSC is used for clinical, scientific and statistical purposes.
Source: Veterinary Anaesthesia and Analgesia - February 12, 2013 Category: Veterinary Research Authors: Matthew McMillan, Jacqueline Brearley Tags: Research Paper Source Type: research

Diagnostic value of serum concentrations of high‐mobility group‐box protein 1 and soluble hemoglobin scavenger receptor in brucellosis
Abstract Both cluster of differentiation (CD)4+ and CD8+ T lymphocytes play key roles in immunity to Brucella, in part because they secrete interferon (IFN)‐γ and activate bactericidal functions in macrophages. Therefore, use of markers of macrophage activation may have diagnostic and prognostic significance. High‐mobility group‐box 1 protein (HMGB1), a late‐onset pro‐inflammatory cytokine, is secreted by activated macrophages. Soluble hemoglobin scavenger receptor (sCD163) is a specific marker of anti‐inflammatory macrophages. The aim of this study was to investigate the diagnostic value of HMGB1 and sCD163 c...
Source: Microbiology and Immunology - February 12, 2013 Category: Microbiology Authors: Ayşe Oğuz Ayarcı, Emel Yılmaz, Deniz Sığırlı, Ferah Budak, Güher Göral, Haluk Barbaros Oral Tags: Original Article Source Type: research

Association between plasma cyclic guanosine monophosphate levels and hemodynamic instability during liver transplantation
In conclusion, this study demonstrates increased baseline cGMP production in patients with ESLD, which is significantly associated with severe hypotension during OLT. We suggest that preoperative levels of cGMP correlate with hemodynamic instability during liver graft reperfusion. Liver Transpl 19:191–198, 2013. © 2012 AASLD.
Source: Liver Transplantation - February 12, 2013 Category: Transplant Surgery Authors: Dmitri Bezinover, Zakiyah Kadry, Tadahiro Uemura, Michael Sharghi, Andrea M. Mastro, Donna M. Sosnoski, Priti Dalal, Piotr K. Janicki Tags: Original Article Source Type: research

Use of Non-Steroidal Anti-Inflammatory Drugs That Elevate Cardiovascular Risk: An Examination of Sales and Essential Medicines Lists in Low-, Middle-, and High-Income Countries
Conclusions Listing of NSAIDs on national EMLs should take account of cardiovascular risk, with preference given to low risk drugs. Diclofenac has a risk very similar to rofecoxib, which was withdrawn from worldwide markets owing to cardiovascular toxicity. Diclofenac should be removed from EMLs. Please see later in the article for the Editors' Summary
Source: PLoS Medicine - February 12, 2013 Category: Internal Medicine Authors: Patricia McGettigan et al. Source Type: research

Congenital hypothyroidism after assisted reproductive technology in Japan: comparison between multiples and singletons, 2005--2009
Conclusions: CH was more frequent in multiples compared to singletons. A higher percentage of additional birth defects was also observed in multiples compared to singletons. The familial aggregation of CH was suggested.
Source: BioMed Central - February 12, 2013 Category: Journals (General) Authors: Syuichi Ooki Source Type: research

The addition of a contralateral routing of signals microphone to a unilateral cochlear implant system—A prospective study in speech outcomes
ConclusionsAdding a contralateral microphone to a unilateral CI resulted in a significant improvement in speech understanding in different conditions. This method could provide a greater cost/benefit ratio than bilateral CIs and be a potential improvement for those who are not candidates for bilateral CIs. Level of Evidence2b. Laryngoscope, 2013
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: Roochi Arora, Hosam Amoodi, Suzanne Stewart, Lendra Friesen, Vincent Lin, Julian Nedzelski, Joseph Chen Tags: Otology/Neurotology Source Type: research

Computer‐assisted assessment of ocular synkinesis: A comparison of methods
ConclusionsThe Facial Assessment by Computer Evaluation program yields rapid, consistent, palpebral fissure width measurements, and when combined with a subjective self‐assessment questionnaire yields a comprehensive measure of ocular synkinesis. Our modified application of the Glasgow Facial Palsy Scale did not appear to be a reliable method for quantitative ocular synkinesis assessment. Level of Evidence3b Laryngoscope, 2013
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: Ingrid J. Kleiss, Marc H. Hohman, Olivia E. Quatela, Henri A. M. Marres, Tessa A. Hadlock Tags: Facial Plastics and Reconstructive Surgery Source Type: research

Lifestyle and Dietary Influences on Nosebleed Severity in Hereditary Hemorrhagic Telangiectasia
ConclusionsThis study supports existing treatments and suggests lifestyle and dietary maneuvers that may also improve nosebleeds in HHT. Level of Evidence2c. Laryngoscope, 2013
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: B. Maneesha Silva, Anna E. Hosman, Hannah L. Devlin, Claire L. Shovlin Tags: General Otolaryngology Source Type: research

Microcomputed tomography analysis of the root canal morphology of single‐rooted mandibular canines
ConclusionsThe anatomy and morphology of the root canal of single‐rooted canines varied widely in different levels of the root.
Source: International Endodontic Journal - February 12, 2013 Category: Dentistry Authors: M. A. Versiani, J. D. Pécora, M. D. Sousa‐Neto Tags: Original Article Source Type: research

Efficacy of reciprocating and rotary techniques for removing filling material during root canal retreatment
ConclusionRemaining endodontic filling material was observed on the canal walls of all teeth regardless of the technique used. Hand files combined with Gates‐Glidden burs (Group I) and the reciprocating technique (Group III) removed more filling material from the canal walls than the Mtwo R files. The reciprocating technique was the most rapid method for removing gutta‐percha and sealer, followed by the rotary technique and the hand file technique.© 2013 International Endodontic Journal. Published by Blackwell Publishing Ltd
Source: International Endodontic Journal - February 12, 2013 Category: Dentistry Authors: AS Zuolo, JE Mello, RS Cunha, ML Zuolo, CES Bueno Tags: Original Scientific Article Source Type: research

Nucleotide variation in IL‐10 and IL‐12 and their receptors and cervical and vulvar cancer risk: A hybrid case–parent triad and case–control study
Given the important role of cell mediated immunity in viral clearance and control of premalignant lesions, we hypothesize that variation in the IL‐12/IL‐10 cytokine and cytokine receptor genes may influence cervical and vulvar cancer risk. We evaluated 76 tagSNPs from seven candidate genes (IL-10, IL-12A, IL-12B, IL-10RA, IL-10RB, IL-12RB1, and IL12RB2) in case–parent sets (n=43 cervical squamous cell carcinoma (SCC), n=96 cervical adenocarcinoma, n=53 vulvar SCC), additional cases (n=356 cervical SCC, n=406 cervical adenocarcinoma, and n=473 vulvar SCC) and population based controls (1,111). We calculated log‐addi...
Source: International Journal of Cancer - February 12, 2013 Category: Cancer & Oncology Authors: Shehnaz K. Hussain, Margaret M. Madeleine, Lisa G. Johnson, Qin Du, Denise A. Galloway, Janet R. Daling, Mari Malkki, Effie W. Petersdorf, Stephen M. Schwartz Tags: Epidemiology Source Type: research

Combined paravertebral and intrathecal vs thoracic epidural analgesia for post-thoracotomy pain relief
Conclusions Although VAS scores were statistically lower in the TEA compared with the PVB+ITO group at some observation points, the differences were small and of questionable clinical relevance. Thus, combined PVB and ITO can be considered a satisfactory alternative to TEA for post-thoracotomy pain relief. ClinicalTrials.gov number. NCT00493909.
Source: British Journal of Anaesthesia - February 12, 2013 Category: Anesthesiology Authors: Dango, S., Harris, S., Offner, K., Hennings, E., Priebe, H.- J., Buerkle, H., Passlick, B., Loop, T. Tags: Regional Anaesthesia Source Type: research

Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial
Conclusions Our study showed that the use of propofol resulted in less hypertension and tachycardia at and after intubation than etomidate. But even with the reduced doses given with the BIS-guided protocol, it often caused significant hypotension.
Source: British Journal of Anaesthesia - February 12, 2013 Category: Anesthesiology Authors: Moller Petrun, A., Kamenik, M. Tags: Clinical Practice Source Type: research

The performance of the K10, K6 and GHQ-12 to screen for present state DSM-IV disorders among disability claimants
Conclusions: The K10 and K6 are reliable and valid scales to screen for present state DSM-IV mental disorder. The optimal cut-off scores are 24 (K10) and 14 (K6). The GHQ-12 (optimal cut-off score: 20) is outperformed by the K10 and K6, which are to be preferred above the GHQ-12. The scores on separate items of the K10 and K6 can be used in disability assessment settings as an agenda for an in-depth follow-up clinical interview to ascertain the presence of present state mental disorder.Johan W Groothoff ,Jac JL van der Klink, Sandra Brouwer, These authors contributed equally to this work
Source: BMC Public Health - Latest articles - February 12, 2013 Category: Consumer Health News Authors: Bert CorneliusJohan GroothoffJac KlinkSandra Brouwer Source Type: research

Heparin‐binding protein (HBP) in critically ill patients with influenza A(H1N1) infection
Abstract Heparin‐binding protein (HBP) is an inducer of vascular endothelial leakage in severe infections. Fluid accumulation into alveoli is a general finding in acute respiratory distress syndrome (ARDS). Severe acute respiratory failure with ARDS is a complication of influenza A(H1N1) infection. Accordingly, we studied the HBP levels in critically ill patients with infection of influenza A(H1N1).Critically ill patients in four intensive care units (ICUs) with polymerase chain reaction (PCR) confirmed infection of influenza A(H1N1) were prospectively evaluated. We collected clinical data and blood samples at ICU admiss...
Source: Clinical Microbiology and Infection - February 12, 2013 Category: Microbiology Authors: K.‐M. Kaukonen, R. Linko, H. Herwald, L. Lindbom, E. Ruokonen, T. Ala‐Kokko, V. Pettilä Tags: Original Article Source Type: research

Detection of mosaicism for the polymorphic variants in the 5′‐UTR of hOGG1 by cloning and sequence analysis and pyrosequencing
Mosaicism refers to the presence of genetically distinct cell lines within an organism or a tissue. Somatic mosaicism exists in distinct populations of somatic cells and commonly arises as a result of somatic mutations, mainly in early embryonic development. Single nucleotide polymorphisms (SNPs) are important markers that distinguish between different individuals in heterogeneous biological samples and contribute greatly to disease risk association‐studies. In this work, we investigated the relationship between the functional variants of the 5′‐UTR of the hOGG1 gene and the risk of Type 2 Diabetes (T2DM). Upon detec...
Source: Electrophoresis - February 12, 2013 Category: Biochemistry Authors: Lili Cao, Tianfeng Li, Yanbei Zhu, Wei Zhou, Wenwen Guo, Zhenming Cai, Yuan Xie, Xuan He, Xinxiu Li, Dalong Zhu, Yaping Wang Tags: Research Article Source Type: research

Effectiveness of the physical activity promotion programme on the quality of life and the cardiopulmonary function for inactive people: Randomized controlled trial
Conclusions: Changes in the quality of life measured with EQ-5D in the group of men who carried out the PAPP were statistically significant when comparing between groups. However changes in cardiopulmonary function were not as relevant when comparing between groups. There was a significant effect within each group in the pulmonary outcomes of values in men, within the experimental group.Trial registration: Developed by the University of Malaga. ClinicalTrials.gov ID: NCT01172483.
Source: BMC Public Health - Latest articles - February 12, 2013 Category: Consumer Health News Authors: Rocio Martin-ValeroAntonio Cuesta-VargasMaría Labajos-Manzanares Source Type: research

The most severe somatic complications of eating disorders and methods of their realimentation. Weight gain as a criterion for successful therapy - a myth. The study of 117 patients with anorexia and bulimia nervosa
Anorexia nervosa and bulimia nervosa are primary psychiatric diseases, which can be characterized by food intake problems. A common phenomenon is the focus of treatment only according to body weight, regardless of the patient's metabolic parameters. However, they are complicated by various somatic consequences which can be lethal in approx. 25–35 percent. These statistical data include all deaths of the patients with eating disorders including influence of drug abuse like psychotropic drugs, laxatives, diuretics, thyroid hormones and alcohol. The deaths are also caused by suicide which is most frequent in bulimia nervosa...
Source: Nutrition - February 11, 2013 Category: Nutrition Authors: M. Navrátilová, J. Jarkovský, J. Tůmová, M. Kalendová, L. Sobotka Tags: Selected Abstracts Source Type: research

Taste sensitivity to 6-n-propylthiouracil is associated with endocannabinoid plasma levels in normal-weight individuals
Conclusions: Our data suggest that a higher disinhibition behavior in NTs may be compensated in part, in normal-weight subjects, by the decrease of peripheral endocannabinoids to downregulate the hunger–energy intake circuitry.
Source: Nutrition - February 11, 2013 Category: Nutrition Authors: Iole Tomassini Barbarossa, Gianfranca Carta, Elisabetta Murru, Melania Melis, Andrea Zonza, Claudia Vacca, Patrizia Muroni, Vincenzo Di Marzo, Sebastiano Banni Tags: Applied Nutritional Investigations Source Type: research

Dairy product consumption, calcium intakes, and metabolic syndrome–related factors over 5 years in the STANISLAS study
Conclusion: In men only, a higher consumption of dairy products was associated with positive changes in the metabolic profile in a 5-y period; a higher calcium consumption was associated with a lower 5-y increase of the BMI and waist circumference.
Source: Nutrition - February 11, 2013 Category: Nutrition Authors: Anastasia Samara, Bernard Herbeth, Ndeye Coumba Ndiaye, Fréderic Fumeron, Stéphanie Billod, Gérard Siest, Sophie Visvikis-Siest Tags: Applied Nutritional Investigations Source Type: research

Hyperglycemia and hypoalbuminemia as prognostic mortality factors in patients with enteral feeding
Abstract: Objective: To determine the association of in-hospital mortality in patients with enteral feeding to their glycemic status (normoglycemia, new hyperglycemia, or diabetes) and their levels of serum albumin.Methods: This was an observational, retrospective, descriptive, and longitudinal study. The data were from patients hospitalized at Hospital de Clínicas “José de San Martín” during a 4-y period who had received enteral feeding during the hospitalization period. P < 0.05 was considered statistically significant.Results: Of the 1004 included patients, 558 (55.6%) had normoglycemia, 219 (21.8%) had known dia...
Source: Nutrition - February 11, 2013 Category: Nutrition Authors: Carlos Alfredo González Infantino, Claudio Daniel González, Ruth Sánchez, Natalia Presner Tags: Applied Nutritional Investigations Source Type: research

Nursing workload in neurological intensive care units: Cross-sectional study
Conclusion: The present results are important for the effective planning and use of nursing resources according to the care needs of patients in neuro-ICUs.
Source: Intensive and Critical Care Nursing - February 11, 2013 Category: Nursing Authors: Alda Ferreira Queijo, Renata Soares Martins, Rafaela Andolhe, Elaine Machado Oliveira, Ricardo Luis Barbosa, Katia Grillo Padilha Tags: Original Articles Source Type: research

Self-assessed oral-health status and quality of life of older Chilean
This study aims to examine the self-assessed oral health status and quality of life (QoL) of independent living Chilean older adults, and their distribution by selected socio-demographic characteristics. The study conducted a secondary analysis of data collected as part of a larger study of dependency which involved 4766 independent living older adults, 60 years of age and older, residents of all Chilean Regions. Participants were interviewed using an 11-module instrument. The majority (61.2%) were female. Mean age was 72.3 (s.d. 8.5) years. 47.5% lived with their spouses/partners. The majority had primary education (63.4%...
Source: Archives of Gerontology and Geriatrics - February 11, 2013 Category: Geriatrics Authors: Rodrigo Mariño, Cecilia Albala, Hugo Sanchez, Ximena Cea, Alejandra Fuentes Source Type: research

Test for screening olfactory function in children
Conclusions: Olfactory evaluation is possible for children as young as 3 years old. Child's age influences the number of odors recognized and the specific odors recognition depends also on the home place geographic location and eating habits. Eastern European children most often recognized the following odors: bubble gum, lemon, cola, mint, toffee and fish, as so these odors were considered for olfactory screening test. The 6 odors test has good ability to generalize performance to olfactory status, has normative data and good validity and reliability, is fast, easy and inexpensive to administer.
Source: International Journal of Pediatric Otorhinolaryngology - February 11, 2013 Category: ENT & OMF Authors: Karolina Dżaman, Beata Zielnik-Jurkiewicz, Dariusz Jurkiewicz, Marta Molińska-Glura Tags: Research papers Source Type: research

Etiologies of pediatric craniofacial injuries: A comparison of injuries involving all-terrain vehicles and golf carts
Conclusions: ATVs and golf carts are often exempt from the safety features and regulations required of motor vehicles, and ATV and golf cart accidents represent a significant portion of pediatric traumas. This study found that ATV and golf cart accidents contribute significantly to craniofacial trauma requiring hospitalization, with resultant morbidity and mortality. Further investigation of these injuries and their prevention in the pediatric population is needed before efforts to promote effective safety regulations for such vehicles in the future can be addressed.
Source: International Journal of Pediatric Otorhinolaryngology - February 11, 2013 Category: ENT & OMF Authors: Lauren C. White, Brian J. McKinnon, C. Anthony Hughes Tags: Research papers Source Type: research

Directed educational training improves coding and billing skills for residents
Conclusions: Billing and coding skill was improved after a single directed education session. Residents, who are not responsible for regular billing and coding, were found to have the greatest improvement in skill. However, providers who regularly bill and code had no significant improvement after this session. These data suggest that a single 90min billing and coding education session is effective in preparing those with limited experience to competently bill and code.
Source: International Journal of Pediatric Otorhinolaryngology - February 11, 2013 Category: ENT & OMF Authors: James R. Benke, Sandra Y. Lin, Stacey L. Ishman Tags: Research papers Source Type: research

Comparison of two different adenoidectomy techniques with special emphasize on postoperative nasal mucociliary clearance rates: Coblation technique vs. cold curettage
Abstract: Objective: To compare the cold curettage and coblation techniques for pediatric adenoidectomy by means of intraoperative blood loss, operation time, and pre- and postoperative nasal mucociliary clearance rates.Methods: The study included 60 consecutive patients undergoing adenoidectomy operation upon the diagnosis of adenoid hypertrophy ranging in age 4–8 years (mean age: 5.82±1.25 years). Two groups consist of 30 patients. The two different adenoidectomy techniques were compared by means of intraoperative blood loss, operation duration, preoperative and postoperative nasal mucociliary clearance rate (NMCR) va...
Source: International Journal of Pediatric Otorhinolaryngology - February 11, 2013 Category: ENT & OMF Authors: Mahmut Özkiriş, Seyhan Karaçavuş, Zeliha Kapusuz, Levent Saydam Tags: Research papers Source Type: research

The TIMP-1 expression in germinal centers of hypertrophied adenoids in children
Conclusion: It is difficult to interpret our results. Our findings did not demonstrate changes in TIMP-1 expression according to age. This may indicate that the processes of hyperplasia, hypertrophy and atrophy of adenoid are not influenced by age and support our thesis that adenoid involution is rather the effect of changes in the number of lymphoid follicles that changes in them. However there is a need for further observational studies of TIMPs and MMPs in adenoid tissue.
Source: International Journal of Pediatric Otorhinolaryngology - February 11, 2013 Category: ENT & OMF Authors: Marcin Musiatowiwcz, Mariusz Koda, Stanisław Sulkowski Tags: Research papers Source Type: research

Preauricular sinuses in the pediatric population: Techniques and recurrence rates
Conclusion: Surgical excision of preauricular sinus under microscope guidance and under methylene blue and probe guidance in our series had very low overall recurrence and complication rates compared to that reported in the literature. The microscope group had a lower recurrence rate in comparison to that of the methylene blue and probe group.
Source: International Journal of Pediatric Otorhinolaryngology - February 11, 2013 Category: ENT & OMF Authors: Eng Cern Gan, Rosslyn Anicete, Henry Kun Kiaang Tan, Abhilash Balakrishnan Tags: Research papers Source Type: research

Combination of symptoms and oxygen desaturation index in predicting childhood obstructive sleep apnea
Abstract: Objective: To develop a screening process of obstructive sleep apnea in children based on a combination of symptoms and oxygen desaturation index (ODI).Materials and Methods: We performed a retrospective study of 141 Chinese patients who were referred to a pediatric sleep laboratory for possible obstructive sleep apnea (OSA). The parents of each patient answered a questionnaire before their child underwent polysomnography (PSG) in the laboratory. An apnea–hypopnea index (AHI) greater than five on nocturnal PSG was defined as OSA. The nocturnal PSG was interpreted by a sleep laboratory physician. The ODI and occ...
Source: International Journal of Pediatric Otorhinolaryngology - February 11, 2013 Category: ENT & OMF Authors: Li Chang, Jianxin Wu, Ling Cao Tags: Research papers Source Type: research

The polymorphisms of the MBL2 and MIF genes associated with Pediatric Cochlear Implant Patients
Conclusion: In this study, we found that a subject who is homozygous for the variant allele B of codon 54 of the MBL2and heterozygous for variant allele C of −173 MIF has a risk factor for sensorineural hearing loss.
Source: International Journal of Pediatric Otorhinolaryngology - February 11, 2013 Category: ENT & OMF Authors: Elif Baysal, Sibel Oguzkan-Balci, Orhan Tunc, Fatih Celenk, Murat Deniz, Muzaffer Kanlikama, Merve Kahraman, Sacide Pehlivan Tags: Research papers Source Type: research

Assessment of masticatory performance, bite force, orthodontic treatment need and orofacial dysfunction in children and adolescents
Conclusion: In the studied sample, age, BMI, BF and the presence of sleep bruxism were related to better MP; but the increase in NOT-S scores was significantly related to poorer MP.
Source: Archives of Oral Biology - February 11, 2013 Category: Dentistry Authors: Maria Carolina Salomé Marquezin, Fernanda Yukie Kobayashi, Ana Bheatriz Marangoni Montes, Maria Beatriz Duarte Gavião, Paula Midori Castelo Tags: Mastication Source Type: research

Tumor size increase following preoperative radiation of soft tissue sarcomas does not affect prognosis
ConclusionOur results indicate that a 20% increase in tumor size following preoperative radiotherapy did not result in a worse outcome for patients when compared to those who had stable or decrease local tumor size following preoperative radiotherapy. J. Surg. Oncol © 2013 Wiley Periodicals, Inc.
Source: Journal of Surgical Oncology - February 11, 2013 Category: Cancer & Oncology Authors: Gadini O. Delisca, Vignesh K. Alamanda, Kristin R. Archer, Yanna Song, Herbert S. Schwartz, Ginger E. Holt Tags: Research Article Source Type: research

Diffusion tensor imaging study of white matter fiber tracts in adolescent attention-deficit/hyperactivity disorder
Abstract: A diffusion tensor imaging (DTI) study was conducted in 12 adolescents with attention deficit/hyperactivity disorder and 14 age- and IQ-matched healthy controls. Inter-subject comparison of fractional anisotropy (FA) of the whole brain between the groups was obtained using the tract-based spatial statistics method. Results revealed significantly lower FA in widespread white matter tracts in cases relative to controls. Also, the FA measure of identified regions was associated with cognitive performance.
Source: Psychiatry Research: Neuroimaging - February 11, 2013 Category: Psychiatry Authors: Tzu-Chao Chuang, Ming-Ting Wu, Sheng-Po Huang, Mei-Jui Weng, Pinchen Yang Tags: Brief reports Source Type: research

Connectomics Sheds New Light on Alzheimer’s Disease
Rapid advances in brain imaging have stimulated studies worldwide on the network architecture of the living brain, revealing general organizational principles in functional systems and the fiber connections that support them. Connectomics, a relatively new field stimulated by revolutionary developments in neuroimaging, has opened up a new landscape of discovery in neuroscience and has led to major international initiatives, such as the Human Connectome Project (http://www.humanconnectomeproject.org). Maps of brain connectivity are shedding light on some of the most tantalizing questions in neuroscience: how the brain is or...
Source: Biological Psychiatry - February 11, 2013 Category: Psychiatry Authors: Arthur W. Toga, Paul M. Thompson Tags: Commentaries Source Type: research

More male calves born after Presynch-Ovsynch protocol with 24-hour timed AI in dairy cows
In conclusion, cows treated with Presynch-Ovsynch protocol and inseminated 24 hours after the last GnRH administration of Ovsynch had a higher sex ratio than cows inseminated 12 hours after standing estrus.
Source: Theriogenology - February 11, 2013 Category: Genetics & Stem Cells Authors: R. Youssefi, M. Vojgani, F. Gharagozlou, V. Akbarinejad Tags: Research articles Source Type: research

Protein kinase A (PKA) pathway is functionally linked to androgen receptor (AR) in the progression of prostate cancer.
CONCLUSION: Our study revealed a novel mechanism to precisely define the functional and clinical interrelationship between the cAMP/PKA pathway and AR signaling in the development of androgen-independent growth of CaPs and metastasis progression. PMID: 23410945 [PubMed - as supplied by publisher]
Source: Urologic Oncology - February 11, 2013 Category: Urology & Nephrology Authors: Sarwar M, Sandberg S, Abrahamsson PA, Persson JL Tags: Urol Oncol Source Type: research

Calcium Renal Lithiasis and Bone Mineral Density. Importance of Bone Metabolism in Urinary Lithiasis.
CONCLUSION: We recommend perform markers of bone turnover and fasting calcium/creatinine in patients with recurrent calcium stones by the significant presence of bone mineral density loss, with a level of evidence III. PMID: 23411066 [PubMed - as supplied by publisher]
Source: Actas Urologicas Espanolas - February 11, 2013 Category: Urology & Nephrology Authors: Arrabal-Polo MA, Sierra Girón-Prieto M, Orgaz-Molina J, Zuluaga-Gómez A, Arias-Santiago S, Arrabal-Martín M Tags: Actas Urol Esp Source Type: research

4D Dark Blood Arterial Wall Magnetic Resonance Imaging: Methodology and Demonstration in the Carotid Arteries.
CONCLUSION: 4D blood suppressed MRI of the human vascular system with submillimeter isotropic spatial resolution is feasible in a clinically reasonable scan time, and data obtained in the carotid arteries show good agreement with established MRI techniques. Future efforts will examine the constellation of data provided by the method and investigate its utility for assessing cardiovascular risk. Magn Reson Med, 2013. © 2013 Wiley Periodicals, Inc. PMID: 23400824 [PubMed - as supplied by publisher]
Source: Magnetic Resonance in Medicine - February 11, 2013 Category: Radiology Authors: Koktzoglou I Tags: Magn Reson Med Source Type: research

Whole-Heart Coronary MRA with 3D Affine Motion Correction Using 3D Image-Based Navigation.
CONCLUSION: We demonstrate that 3D-NAV and 3D affine correction can be used to acquire Cartesian whole-heart 3D coronary artery images with 100% scan efficiency with similar image quality as with the state-of-the-art gated and corrected method with approximately 50% scan efficiency. Magn Reson Med, 2013. © 2013 Wiley Periodicals, Inc. PMID: 23400902 [PubMed - as supplied by publisher]
Source: Magnetic Resonance in Medicine - February 11, 2013 Category: Radiology Authors: Henningsson M, Prieto C, Chiribiri A, Vaillant G, Razavi R, Botnar RM Tags: Magn Reson Med Source Type: research

Examining the Association of Health Literacy and Health Behaviors in African American Older Adults: Does Health Literacy Affect Adherence to Antihypertensive Regimens?
This study examined the association of health literacy and adherence behaviors in African American older adults (N = 121) with hypertension using a descriptive correlational design. Health literacy was measured using the Rapid Estimate of Adult Literacy in Medicine survey, and adherence was measured using the Hill-Bone Compliance Scale. Most of the participants were functioning with inadequate health literacy. No statistically significant association was found between health literacy and adherence, but regression analysis showed that age and health status significantly predicted adherence: Those who were younger and report...
Source: Journal of Gerontological Nursing - February 11, 2013 Category: Nursing Authors: Ingram RR, Ivanov LL Tags: J Gerontol Nurs Source Type: research

Assessment of the sealing abilities of several root canal sealers and filling methods.
Conclusions. AH Plus and GuttaFlow sealers showed similar levels of sealing ability. The continuous wave of condensation technique had the best sealing capability when compared to the other techniques. PMID: 23394208 [PubMed - as supplied by publisher]
Source: Acta Odontologica Scandinavica - February 11, 2013 Category: Dentistry Authors: Ozcan E, Eldeniz AU, Aydınbelge HA Tags: Acta Odontol Scand Source Type: research

The Response of the Composite Variability Index to a Standardized Noxious Stimulus During Propofol-Remifentanil Anesthesia.
CONCLUSION:In paralyzed patients, ΔsEMG and ΔCVI might help identify inadequately low levels of analgesia with an acceptable sensitivity and specificity. The impact of profound neuromuscular block on the CVI should be investigated in further studies. PMID: 23400975 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - February 11, 2013 Category: Anesthesiology Authors: Ellerkmann RK, Grass A, Hoeft A, Soehle M Tags: Anesth Analg Source Type: research