Statistics Research This is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 34.

Crucial information needs of ICU charge nurses in Finland and Greece
ConclusionsAccurate and real‐time information is a prerequisite for ICU charge nurses' ad hoc decision‐making during daily care management. Identification of the most crucial information is needed when tools for information management are developed.Relevance to clinical practice:The results of this study indicated that a major portion of immediate information needs of ICU charge nurses are internationally common in similar settings.
Source: Nursing in Critical Care - January 1, 2013 Category: Nursing Authors: Heljä Lundgrén‐Laine, Maria Kalafati, Elina Kontio, Tommi Kauko, Sanna Salanterä Tags: Research Source Type: research

Genome‐wide DNA methylation analysis in alcohol dependence
We present evidence that alterations in DNA methylation may be associated with AD, which is consistent with epigenetic theory.
Source: Addiction Biology - January 1, 2013 Category: Addiction Authors: Ruiling Zhang, Qin Miao, Chuansheng Wang, Rongrong Zhao, Wenqiang Li, Colin N. Haile, Wei Hao, Xiang Yang Zhang Tags: Original Article Source Type: research

Inhalation anesthetics and the reproductive risk associated with occupational exposure among women working in veterinary anesthesia
ConclusionsThis study did not show a statistically significant difference in reproductive risk for women working in veterinary anesthesia when compared to women working in veterinary critical care. Overall the incidence for reproductive health problems is similar to the risk for the general population of females in North America.
Source: Veterinary Anaesthesia and Analgesia - January 1, 2013 Category: Veterinary Research Authors: Sandra I Allweiler, Lori R Kogan Tags: Short Communication Source Type: research

Pain and the Alpha‐Sleep Anomaly: A Mechanism of Sleep Disruption in Facioscapulohumeral Muscular Dystrophy
ConclusionsChronic musculoskeletal pain is frequent in FSHD patients, and it represents a major mechanism of sleep disruption.
Source: Pain Medicine - January 1, 2013 Category: Anesthesiology Authors: Giacomo Della Marca, Roberto Frusciante, Catello Vollono, Elisabetta Iannaccone, Serena Dittoni, Anna Losurdo, Elisa Testani, Valentina Gnoni, Salvatore Colicchio, Chiara Di Blasi, Carmen Erra, Salvatore Mazza, Enzo Ricci Tags: Original Article Source Type: research

Individualized two‐stage multiple testing procedures with corresponding interval estimates
We present an alternative method of constructing multiple testing procedures (MTPs) that easily admits corresponding interval estimates. The new method places greater focus on each hypothesis separately while still using all the data. This method is particularly effective in the dependent case. Not only do these new MTPs perform as well as commonly used stepwise procedures but they also have a practical interval property not usually shared by stepwise procedures. That is, acceptance regions have desirable convexity properties. Furthermore, interval estimates associated with these tests are easily obtained. In addition, the...
Source: Biometrical Journal - January 1, 2013 Category: Biotechnology Authors: Arthur Cohen, Yingqiu Ma, Harold B. Sackrowitz Tags: Article Source Type: research

Pelvic floor muscle training included in a pregnancy exercise program is effective in primary prevention of urinary incontinence: A randomized controlled trial
ConclusionPFMT taught in a general exercise class three times per week for at least 22 weeks, without former assessment of ability to perform a correct contraction was effective in primary prevention of UI in primiparous pregnant women. Neurourol. Urodynam. © 2013 Wiley Periodicals, Inc.
Source: Neurourology and Urodynamics - January 1, 2013 Category: Urology & Nephrology Authors: Mireia Pelaez, Silvia Gonzalez‐Cerron, Rocío Montejo, Rubén Barakat Tags: Original Clinical Article Source Type: research

Usability and Potential of Geostatistics for Spatial Discrimination of Multiple Sclerosis Lesion Patterns
CONCLUSIONSThis method in development is a promising candidate to complement standard image‐based statistics by incorporating spatial quantification. The work flow is generic and not limited to analyzing MS lesion patterns. It can be completely automated for the screening of radiological archives.
Source: Journal of Neuroimaging - January 1, 2013 Category: Radiology Authors: Robert Marschallinger, Stefan M. Golaszewski, Alexander B. Kunz, Martin Kronbichler, Gunther Ladurner, Peter Hofmann, Eugen Trinka, Mark McCoy, Jörg Kraus Tags: Experimental Laboratory Research Source Type: research

Impact of Model for End-Stage Liver Disease in the Occurrence of Infectious Events and Survival in a Cohort of Liver Transplant Recipients
Abstract: The Model for End-Stage Liver Disease (MELD), which predicts mortality on the waiting list before liver transplantation, has changed organ allocation criteria to prioritize severely ill patients. The aim of this study was to investigate the impact of the new criteria on the incidence of Healthcare Associated Infections (HAI) and patient survival after liver transplantation. This retrospective cohort included liver transplant recipients from 2005 to 2007. Infection notification followed the recommended criteria of the National Healthcare Safety Network (NHSN). Statistical analysis was performed using the Statisti...
Source: Transplantation Proceedings - January 1, 2013 Category: Transplant Surgery Authors: W.T. Clemente, R.M.C. Romanelli, L.C. Faria, S.S.S. Lima, L.A. Jesus, J.R.G. Cortes, M.D. Sanches, O.L. Cançado, A.S. Lima Tags: Liver Transplantation Source Type: research

Long-term Factors Influencing Survial After Kidney Transplantation
This study applied the methods of literature review and Delphi analysis. The recovery rate of the investigative questionnaire was 100%. Experts variation coefficient was 0.13. Through the statistical analysis, we obtained 12 major influencing factors and 144 detailed indicators final. Through the weighted average, we sequenced the factors according to their importance.
Source: Transplantation Proceedings - January 1, 2013 Category: Transplant Surgery Authors: G. Dongping, L. Yang, S. Xiaobei, X. Junxiang, Y. Yuan, C. Hui Tags: Renal Transplantation Source Type: research

Capecitabine to Reduce Nonmelanoma Skin Carcinoma Burden in Solid Organ Transplant Recipients
ConclusionsSOTRs experienced a clinically and statistically significant decline in incident SCCs during treatment with low‐dose oral capecitabine, with varying degrees of side effects. Larger randomized trials will determine the dose and efficacy of capecitabine for adjuvant treatment of NMSC in SOTRs.
Source: Dermatologic Surgery - January 1, 2013 Category: Dermatology Authors: Bart Endrizzi, Rehana L. Ahmed, Theresa Ray, Arkadiusz Dudek, Peter Lee Tags: Original Article Source Type: research

Complementary and Alternative Medicine Consultations in Urban and Nonurban Areas: A National Survey of 1427 Australian Women
Conclusions: For the population sample studied, the higher overall consultation rates with CAM therapists by Australian nonurban women were caused by consultations for chiropractic care.
Source: Journal of Manipulative and Physiological Therapeutics - January 1, 2013 Category: Complementary Medicine Authors: Jon Adams, David Sibbritt, Alex Broom, Deborah Loxton, Jon Wardle, Marie Pirotta, Chi-Wai Lui Tags: Original Articles Source Type: research

Focal and segmental glomerulosclerosis in renal allograft recipients: A clinico-pathologic study of 37 cases.
Abstract Focal and segmental glomerulosclerosis (FSGS) in renal allografts may occur as a recurrence of primary FSGS, as a de novo phenomenon or as a complication of calcineurin inhibitor toxicity. There are very few studies in the literature describing the clinico-pathologic characteristics of FSGS in renal allografts. To the best of our knowledge, no such study exists from the Indian subcontinent. Thirty-seven cases showing FSGS, of 426 transplant biopsies performed over a 4-year period (2006-2009), were included in this study. The pre- and post-transplant clinical data were noted. FSGS was classified as per the ...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2013 Category: Urology & Nephrology Authors: Gupta R, Sharma A, Mahanta PJ, Agarwal SK, Dinda AK Tags: Saudi J Kidney Dis Transpl Source Type: research

Mucocutaneous manifestations and nail changes in patients with end-stage renal disease on hemodialysis.
This study was undertaken to determine the prevalence of mucocutaneous manifestations in patients with end-stage renal disease (ESRD) who are on HD. In this cross-sectional, descriptive and analytic study conducted in 2009, 100 patients on HD at the Five Azar Hospital in Gorgan city were randomly selected. All the patients underwent detailed examination by a dermatologist to look for lesions in the skin, hair, nail and mucous membranes; if felt necessary, biopsy was obtained from the lesions. The findings were statistically analyzed using SPSS-13 software. For evaluation of normality of distribution, Kolmogorov-Smirnov was...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2013 Category: Urology & Nephrology Authors: Tajbakhsh R, Dehghan M, Azarhoosh R, Haghighi AN, Sadani S, Zadeh SS, Kabootari M, Qorbani M Tags: Saudi J Kidney Dis Transpl Source Type: research

Risk factors for renal scarring in children with primary vesicoureteral reflux disease.
Abstract To determine the incidence of renal scarring among patients with primary vesicoureteral reflux (VUR) and the possible risk factor(s), we studied 90 children (60 girls and 30 boys) with VUR followed in the Pediatric Nephrology Unit at the Ege University Hospital from 1998 to 2003. All the patients were assessed for VUR grade by voiding cystoureterography and for presence of renal scarring by (99 m) technetium dimercapto-succinic acid scintigraphy. All infants with VUR were given low-dose prophylactic antibiotics and followed-up until resolution of the reflux. Grade of reflux and number of urinary tract infe...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2013 Category: Urology & Nephrology Authors: Mir S, Ertan P, Ozkayin N Tags: Saudi J Kidney Dis Transpl Source Type: research

[Postoperative complications of microscopic versus Palomo varicocelectomy for varicocele in army personnel].
CONCLUSION: Microscopic varicocelectomy can be a good choice in the treatment of varicocele in army personnel. PMID: 23353175 [PubMed - in process]
Source: Journal of Southern Medical University - January 1, 2013 Category: Universities & Medical Training Authors: Zeng JH, Hu WL, Luo HH, Wang X, Cao JX, Xie JJ, Lu YJ, Peng YH Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

[Impact of the Water for All Program (PAT) on childhood morbidity and mortality from diarrhea in the Bahia State, Brazil.]
This study aimed to evaluate the impact of the Water for All Program (PAT), launched in Bahia State, Brazil, with the objective of expanding coverage of the water supply and sanitation in areas with high vulnerability to waterborne diseases. A total of 224 municipalities (counties) with adequate vital statistics were selected. A controlled before-and-after study design was used, performing analyses with multivariate negative binomial regression with fixed effects, from 2005 to 2008. PAT coverage - as a continuous variable - was negatively associated (p < 0.01) with the under-five mortality rate. Municipalities with cove...
Source: Cadernos de Saude Publica - January 1, 2013 Category: Global & Universal Authors: Rasella D Tags: Cad Saude Publica Source Type: research

[Tuberculosis among adolescents in two Brazilian State capitals.]
Abstract The study analyzed clinical, laboratory, and radiological characteristics of tuberculosis (TB) among adolescents from two Brazilian State capitals, according to the 2010 Updated Guidelines of the National TB Control Program (NTPC) through a descriptive, retrospective cross-sectional study of reported TB cases from Manaus and Salvador from 1996 to 2003. Patients were divided into two groups: 10 to 14 years and 15 to 19 years of age. Variables were studied through descriptive statistics; 1,781 adolescents were included; 928 (52.1%) were males. Median age was 16 years (SD = 2.3). Pulmonary TB (PTB) occurred i...
Source: Cadernos de Saude Publica - January 1, 2013 Category: Global & Universal Authors: Sant'anna CC, Schmidt CM, March MD, Pereira SM, Barreto ML Tags: Cad Saude Publica Source Type: research

Traffic deaths: recent evolution and regional differences in Bahia State, Brazil.
This study describes the temporal evolution of mortality due to traffic accidents in regions within Bahia State, Brazil, from 1996 to 2007, using data from the Brazilian Mortality Information System. We calculated overall rates of mortality due to traffic accidents and specific rates by type of victim. Temporal evolution was analyzed by means of correlations between rates and years of study, as well as polynomial regression models to evaluate trends. During the study period, the regions analyzed accounted for 60% of deaths due to traffic accidents in Bahia. Excess mortality among males and superior percentage of deaths in ...
Source: Cadernos de Saude Publica - January 1, 2013 Category: Global & Universal Authors: Rios PA, Mota EL Tags: Cad Saude Publica Source Type: research

[Validation of reported location of solid waste using Procrustes analysis in the context of a participatory community initiative.]
This study is part of a community initiative for integrated solid waste management based on "popular epidemiology" and participatory action research. The study proposes a method for validation of spatial data (X and Y data) on solid waste reported by community members. Location of sites was conducted by 76 residents of the La Nopalera community (Yautepec, Morelos, Mexico) and compared with reports by three environmental health experts. Agreement was explored using Procrustes analysis. Experts identified 23 sites with abundant solid waste, while community members only identified 22 sites. There were minimal differences in l...
Source: Cadernos de Saude Publica - January 1, 2013 Category: Global & Universal Authors: Pacheco-Magaña LE, Idrovo AJ, Arenas-Monreal L, Cortez-Lugo M, Sánchez-Zamorano LM Tags: Cad Saude Publica Source Type: research

Professional formation and deformation: repression of personal values and qualities in medical education.
CONCLUSIONS: An international cadre of Healer's Art students identified core personal qualities and values that they may not reveal or feel may be diminished in medical school. Medical training involves not only professional formation but exposure to professional deformation as well. Educators must attend to both gains in professional competence and the personal qualities and values that are at risk in the course of professional development. PMID: 23334962 [PubMed - in process]
Source: Famly Medicine - January 1, 2013 Category: Primary Care Authors: Rabow MW, Evans CN, Remen RN Tags: Fam Med Source Type: research

Comparative study and histomorphometric analysis of bone allografts lyophilized and sterilized by autoclaving, gamma irradiation and ethylene oxide in rats.
CONCLUSION: The three sterilization methods cause similar effects on bone allografts regarding macroscopic and histomorphometric parameters. PMID: 23338116 [PubMed - in process]
Source: Acta Cirurgica Brasileira - January 1, 2013 Category: Surgery Authors: Almeida OM, Jorgetti W, Oksman D, Jorgetti C, Rocha DL, Gemperli R Tags: Acta Cir Bras Source Type: research

Effects of preoperative irradiation using fractioned electron beam on the healing process of colocolonic anastomosis in rats undergoing early and late surgical intervention.
CONCLUSION: The irradiation in divided doses increased local inflammatory cellularity when the surgery was performed later. This result did not affect the increase of complications, nor on the local concentration of collagen, achieving similar clinical outcomes. PMID: 23338117 [PubMed - in process]
Source: Acta Cirurgica Brasileira - January 1, 2013 Category: Surgery Authors: Simões Neto J, Reis Neto JA, Matos D Tags: Acta Cir Bras Source Type: research

A proposal for evaluating the validity of holistic-based admission processes.
Conclusions. Such research evidence is critical for establishing the validity of widely used holistic admission approaches. PMID: 23330903 [PubMed - in process]
Source: Teaching and Learning in Medicine - January 1, 2013 Category: Universities & Medical Training Authors: Kreiter CD Tags: Teach Learn Med Source Type: research

Comparison of the diagnostic performance of response evaluation criteria in solid tumor 1.0 with response evaluation criteria in solid tumor 1.1 on MRI in advanced breast cancer response evaluation to neoadjuvant chemotherapy.
CONCLUSION: RECIST 1.1 showed better diagnostic performance than RECIST 1.0, although there was no statistically significant difference between the two. PMID: 23323026 [PubMed - in process]
Source: Korean J Radiol - January 1, 2013 Category: Radiology Authors: Jeh SK, Kim SH, Kang BJ Tags: Korean J Radiol Source Type: research

Image reporting and characterization system for ultrasound features of thyroid nodules: multicentric korean retrospective study.
CONCLUSION: The predictor model using suspicious malignant US features may be helpful in risk stratification of thyroid nodules. PMID: 23323040 [PubMed - in process]
Source: Korean J Radiol - January 1, 2013 Category: Radiology Authors: Kwak JY, Jung I, Baek JH, Baek SM, Choi N, Choi YJ, Jung SL, Kim EK, Kim JA, Kim JH, Kim KS, Lee JH, Lee JH, Moon HJ, Moon WJ, Park JS, Ryu JH, Shin JH, Son EJ, Sung JY, Na DG, Korean Society of Thyroid Radiology (KSThR), Korean Society of Radiology Tags: Korean J Radiol Source Type: research

Optimizing imaging quality and radiation dose by the age-dependent setting of tube voltage in pediatric chest digital radiography.
CONCLUSION: Protocol C (higher kVp) may help optimize the trade-off between radiation dose and image quality, and it may be acceptable for use in a pediatric age group from these results. PMID: 23323043 [PubMed - in process]
Source: Korean J Radiol - January 1, 2013 Category: Radiology Authors: Guo H, Liu WY, He XY, Zhou XS, Zeng QL, Li BY Tags: Korean J Radiol Source Type: research

Clinician Suspicion of an Alcohol Problem: An Observational Study From the AAFP National Research Network.
CONCLUSION Clinician suspicion of alcohol problems had poor sensitivity but high specificity for identifying patients who had a positive screening test for alcohol problems. These data support the routine use of a screening tool to supplement clinicians' suspicions, which already provide reasonable positive predictive value. PMID: 23319506 [PubMed - in process]
Source: Annals of Family Medicine - January 1, 2013 Category: Primary Care Authors: Vinson DC, Turner BJ, Msed, Manning BK, Galliher JM Tags: Ann Fam Med Source Type: research

Symptoms and risk factors to identify men with suspected cancer in primary care: derivation and validation of an algorithm.
CONCLUSION: The algorithm has good discrimination and could be used to identify those at highest risk of cancer to facilitate more timely referral and investigation. PMID: 23336443 [PubMed - in process]
Source: The British Journal of General Practice - January 1, 2013 Category: Primary Care Authors: Hippisley-Cox J, Coupland C Tags: Br J Gen Pract Source Type: research

Symptoms and risk factors to identify women with suspected cancer in primary care: derivation and validation of an algorithm.
CONCLUSION: The algorithm has good discrimination and could be used to identify those at highest risk of cancer to facilitate more timely referral and investigation. PMID: 23336450 [PubMed - in process]
Source: The British Journal of General Practice - January 1, 2013 Category: Primary Care Authors: Hippisley-Cox J, Coupland C Tags: Br J Gen Pract Source Type: research

Reducing the time before consulting with symptoms of lung cancer: a randomised controlled trial in primary care.
CONCLUSION: Behavioural intervention in primary care shortened the time individuals at high risk of lung disease intended to take before consulting with new chest symptoms (the secondary outcome of the study), but increases in consultation rates and the proportions of consultations within target times were not statistically significant. PMID: 23336469 [PubMed - in process]
Source: The British Journal of General Practice - January 1, 2013 Category: Primary Care Authors: Smith S, Fielding S, Murchie P, Johnston M, Wyke S, Powell R, Devereux G, Nicolson M, Macleod U, Wilson P, Ritchie L, Lee AJ, Campbell NC Tags: Br J Gen Pract Source Type: research

Pediatric liver transplantation outcomes in Korea.
This study presents the epidemiologic data for nearly all pediatric liver transplantation in Korea and shows that the independent prognostic factors in patient survival are chronic rejection and retransplantation. PMID: 23341710 [PubMed - in process]
Source: J Korean Med Sci - January 1, 2013 Category: Journals (General) Authors: Kim JM, Kim KM, Yi NJ, Choe YH, Kim MS, Suh KS, Kim SI, Lee SK, Lee SG Tags: J Korean Med Sci Source Type: research

Diagnostic Accuracy of Tissue Impedance Measurement Interpretation for Correct Veress Needle Placement in Canine Cadavers
ConclusionsDiagnostic accuracy of TIMI for Veress needle placement was higher than has been reported for other tests, and TIMI had a shallow learning curve. TIMI successfully detected all incorrect Veress needle placements. Further prospective evaluation of Veress needle placement with and without TIMI is warranted to determine if its use increases operator detection of inappropriate Veress needle placements or decreases installment phase complication rates.
Source: Veterinary Surgery - January 1, 2013 Category: Veterinary Research Authors: Jacqueline C. Whittemore, Amanda Mitchell, Sara Hyink, Ann Reed Tags: Original Article: Research Source Type: research

Correlation between clinical manifestations of nocturnal enuresis and attentional performance in children with attention deficit hyperactivity disorder (ADHD).
CONCLUSION: Children with ADHD have a high prevalence of NE. ADHD children with NE had a significantly higher dysfunctional voiding symptom score and shorter reaction time in most domains of the TAP test. Further study is needed to discern the impact of NE on the neuropsychological function of ADHD children. PMID: 23332428 [PubMed - in process]
Source: J Formos Med Assoc - January 1, 2013 Category: Journals (General) Authors: Yang TK, Huang KH, Chen SC, Chang HC, Yang HJ, Guo YJ Tags: J Formos Med Assoc Source Type: research

Enhancing the h index for the objective assessment of healthcare researcher performance and impact.
Conclusions This study supports the construct validity of the h index as a measure of healthcare researcher academic rank. It also identifies the assessment value of our developed indices of h(2) upper, h(2) centre, h(2) lower and sRM. These can be applied in combination with the h index to provide additional objective evidence to appraise the performance and impact of an academic healthcare researcher. PMID: 23358276 [PubMed - in process]
Source: J R Soc Med AND (has... - January 1, 2013 Category: Journals (General) Authors: Patel VM, Ashrafian H, Bornmann L, Mutz R, Makanjuola J, Skapinakis P, Darzi A, Athanasiou T Tags: J R Soc Med Source Type: research

So Close, So Far Away: Analysis of Surnames in a Town of Twins (Cândido GodÓi, Brazil)
Summary Cândido GodÓi is a small Brazilian town known for high rates of twin birth. In 2011, a genetic study showed that this localized high rate of twin births could be explained by a genetic founder effect. Here we used isonymic analysis and surname distribution to identify population subgroups within 5316 inhabitants and 665 different surnames. Four clusters were constructed based on different twin rates (P < 0.001; MRPP test). Fisher's α and consanguinity index showed low and high values, respectively, corresponding with observed values in isolated communities with high levels of genetic drift. Values of A and B ...
Source: Annals of Human Genetics - January 1, 2013 Category: Genetics & Stem Cells Authors: Marcelo Zagonel De Oliveira, Lavínia Schüler‐Faccini, Dario A. Demarchi, Emma L. Alfaro, José E. Dipierri, Mauricio R. Veronez, Marlise Colling Cassel, Alice Tagliani‐Ribeiro, Ursula Silveira Matte, Virginia Ramallo Tags: Original Article Source Type: research

Results of phenol red thread test in clinically normal Syrian hamsters (Mesocricetus auratus)
ConclusionThis study provides novel data for normal reference ranges of PRTT values in healthy Syrian hamsters. Results of this study may assist veterinarians in the diagnosis of ocular surface disease and syndromes affecting the tear film in these species.
Source: Veterinary Ophthalmology - January 1, 2013 Category: Veterinary Research Authors: Seyed Mehdi Rajaei, Reza Sadjadi, Amin Sabzevari, M. Selk Ghaffari Tags: Original Article Source Type: research

Sample size determination for testing equality in Poisson frequency data under an AB/BA crossover trial
Assuming that the frequency of occurrence follows the Poisson distribution, we develop sample size calculation procedures for testing equality based on an exact test procedure and an asymptotic test procedure under an AB/BA crossover design. We employ Monte Carlo simulation to demonstrate the use of these sample size formulae and evaluate the accuracy of sample size calculation formula derived from the asymptotic test procedure with respect to power in a variety of situations. We note that when both the relative treatment effect of interest and the underlying intraclass correlation between frequencies within patients are l...
Source: Pharmaceutical Statistics - January 1, 2013 Category: Statistics Authors: Kung‐Jong Lui Tags: Main Paper Source Type: research

Rivaroxaban: an oral factor xa inhibitor.
CONCLUSIONS: Based on the findings of the studies reported in this review, rivaroxaban is an effective option for the prevention of VTE after orthopedic surgery, stroke prevention for nonvalvular AF, and treatment of VTE. At this time, rivaroxaban cannot be recommended for secondary risk reduction after ACS because of the increased bleeding risk. PMID: 23328267 [PubMed - in process]
Source: Clinical Therapeutics - January 1, 2013 Category: Drugs & Pharmacology Authors: Thomas TF, Ganetsky V, Spinler SA Tags: Clin Ther Source Type: research

Comparison of Antiplatelet Efficacy and Tolerability of Clopidogrel Napadisilate With Clopidogrel Bisulfate in Coronary Artery Disease Patients After Percutaneous Coronary Intervention: A Prospective, Multicenter, Randomized, Open-Label, Phase IV, Noninferiority Trial.
CONCLUSIONS: In this study of CAD Korean patients who have undergone PCI, the antiplatelet efficacy of clopidogrel napadisilate was noninferior to that of clopidogrel bisulfate after 4 weeks of maintenance treatment. No statistically significant difference was found in tolerability between the 2 treatment groups. ClinicalTrials.gov identifier: NCT01584791. PMID: 23328268 [PubMed - in process]
Source: Clinical Therapeutics - January 1, 2013 Category: Drugs & Pharmacology Authors: Park JB, Koo BK, Choi WG, Kim SY, Park J, Kwan J, Park CG, Kim HS Tags: Clin Ther Source Type: research

Occupationally Related Contact Dermatitis in North American Food Service Workers Referred for Patch Testing, 1994 to 2010.
CONCLUSIONS: Among FSWs patch tested by the NACDG between 1994 and 2010, the most common allergens were thiuram mix and carba mix. Gloves were the most common source of responsible allergens. PMID: 23340395 [PubMed - as supplied by publisher]
Source: Dermatitis - January 1, 2013 Category: Dermatology Authors: Warshaw EM, Kwon GP, Mathias CG, Maibach HI, Fowler JF, Belsito DV, Sasseville D, Zug KA, Taylor JS, Fransway AF, Deleo VA, Marks JG, Pratt MD, Storrs FJ, Zirwas MJ, Dekoven JG Tags: Dermatitis Source Type: research

Effect of concurrent prescription antiarthralgia pharmacotherapy on persistence to aromatase inhibitors in treatment-naive postmenopausal females.
CONCLUSIONS: Postmenopausal females treatment-naïve to aromatase inhibitor therapy who also received treatment with a prescription antiarthralgia medication did not have significantly higher persistence with aromatase inhibitor therapy. Further research should focus on other possible causes of poor persistence in patients using aromatase inhibitor therapy. PMID: 23324501 [PubMed - in process]
Source: The Annals of Pharmacotherapy - January 1, 2013 Category: Drugs & Pharmacology Authors: Hashem MG, Cleary K, Fishman D, Nichols L, Khalid M Tags: Ann Pharmacother Source Type: research

National utilization patterns of warfarin use in older patients with atrial fibrillation: a population-based study of medicare part d beneficiaries.
CONCLUSIONS: Warfarin use rates vary by patient characteristics and region, with higher rates among residents of the Midwest and among patients seen by cardiologists and PCPs. Preventing stroke-related disability in AF requires implementation of evidence-based initiatives to increase warfarin use. PMID: 23324508 [PubMed - in process]
Source: The Annals of Pharmacotherapy - January 1, 2013 Category: Drugs & Pharmacology Authors: Raji MA, Lowery M, Lin YL, Kuo YF, Baillargeon J, Goodwin JS Tags: Ann Pharmacother Source Type: research

A Likelihood Ratio Test for Genome‐Wide Association under Genetic Heterogeneity
Summary Most existing association tests for genome‐wide association studies (GWASs) fail to account for genetic heterogeneity. Zhou and Pan proposed a binomial‐mixture‐model‐based association test to account for the possible genetic heterogeneity in case‐control studies. The idea is elegant, however, the proposed test requires an expectation‐maximization (EM)‐type iterative algorithm to identify the penalised maximum likelihood estimates and a permutation method to assess p‐values. The intensive computational burden induced by the EM‐algorithm and the permutation becomes prohibitive for direct application...
Source: Annals of Human Genetics - January 1, 2013 Category: Genetics & Stem Cells Authors: Meng Qian, Yongzhao Shao Tags: Original Article Source Type: research

Cytologic and cystoscopic predictors of recurrence and progression in patients with low‐grade urothelial carcinoma
CONCLUSIONS:Cystoscopic findings, such as the presence of multiple lesions, together with concurrent positive or suspicious urine cytology, were associated with recurrence or progression of LGUC. These findings may help to identify high‐risk patients. Cancer (Cancer Cytopathol) 2012;. © 2012 American Cancer Society.
Source: Cancer Cytopathology - January 1, 2013 Category: Pathology Authors: Julie Jackson, Güliz A. Barkan, Umesh Kapur, Eva M. Wojcik Tags: Original Article Source Type: research

Impact of Traveling to Visit Friends and Relatives on Chronic Disease Management
ConclusionsThis study identified a high proportion of problems related to chronic conditions experienced during VFR travel, while pre‐travel appointments tended to focus on infectious disease prevention. A greater emphasis on medication adherence and chronic disease management during VFR travel is also needed during pre‐travel preparations.
Source: Journal of Travel Medicine - January 1, 2013 Category: Infectious Diseases Authors: Holly E. Gurgle, David J. Roesel, Tiffany N. Erickson, Emily Beth Devine Tags: ORIGINAL ARTICLE Source Type: research

The decrease of mean platelet volume after extracorporeal LDL-cholesterol elimination.
CONCLUSION: Mean platelet volume is easily available and is often disregarded, and sometimes may suggest the need for a careful assessment in patients with familial hypercholesterolemia. Mean platelet volume could be one of the markers of therapeutic efficacy in patients with familial hypercholesterolemia treated by extracorporeal LDL-cholesterol elimination that is simple and inexpensive. PMID: 23357146 [PubMed - in process]
Source: Atherosclerosis. Supplements. - January 1, 2013 Category: Cardiology Authors: Blaha M, Kostal M, Lanska M, Blaha V, Foralova I, Filip S, Kubisova M, Maly J Tags: Atheroscler Suppl Source Type: research

Homocysteine in lipoprotein apheresis patients - Retrospective data analysis in apheresis center of a university hospital.
CONCLUSIONS: The prevalence of hyperhomocysteinemia in lipoprotein apheresis patients is high. Neither apheresis nor more conventional methods appear to markedly influence homocysteine serum levels. PMID: 23357153 [PubMed - in process]
Source: Atherosclerosis. Supplements. - January 1, 2013 Category: Cardiology Authors: Tselmin S, Rodionov RN, Müller G, Bornstein S, Julius U Tags: Atheroscler Suppl Source Type: research

Replication of an experiment on extremely diluted thyroxine and highland amphibians.
Abstract INTRODUCTION: The purpose of this study was to reproduce an experiment with diluted thyroxine and amphibians. A detailed account of the difficulties of this line of research has been published by the initial team (Endler and Scherer-Pongratz). One experiment which has been reported reproducible by the initial team and independent researchers is the effect of extremely diluted agitated thyroxine (T30x) versus analogously prepared water (W30x) in amphibians from biotopes above the tree line (highland amphibians). METHODS: (A) The author replicated the experiment. Rana temporaria were taken from an alpine...
Source: Homeopathy - January 1, 2013 Category: Complementary Medicine Authors: Harrer B Tags: Homeopathy Source Type: research

Homeopathic treatment of premenstrual syndrome: a case series.
CONCLUSIONS: Homeopathic treatment was well tolerated and seemed to have a positive impact on PMS symptoms. Folliculinum was the most frequent homeopathic medicine prescribed. There appears to be scope for a properly designed, randomized, placebo-controlled trial to investigate the efficacy of individual homeopathic medicines in PMS. PMID: 23290881 [PubMed - in process]
Source: Homeopathy - January 1, 2013 Category: Complementary Medicine Authors: Danno K, Colas A, Terzan L, Bordet MF Tags: Homeopathy Source Type: research

Degenerative trends of the palmaris longus muscle in a South African population
The literature reports that the palmaris longus muscle (PL) is only found in mammals in which the forelimbs are weight‐bearing extremities. It is suggested that the function of this muscle has been taken over by the other flexors in the forearm. Terms used in the literature to describe the diminishing of this muscle include retrogressive or phylogenetic degenerative trends. The aims of this study were to determine the prevalence of PL in a South African population and whether a phylogenetic degenerative trend for the PL exists. To determine the prevalence of the PL, five groups, representing different age intervals (Year...
Source: Clinical Anatomy - January 1, 2013 Category: Anatomy Authors: G. Venter, A.N. Schoor, M.C. Bosman Tags: Original Communication Source Type: research