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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 7.
[Correspondence] Reanalysis of “Bedside detection of awareness in the vegetative state: a cohort study”
In 2011, Damian Cruse and colleagues reported that a new EEG-based tool was able to show that three of 16 patients in a vegetative state performed a motor imagery task requiring language and short-term memory. This finding, if confirmed, has major implications for diagnosis and care of severely brain-injured patients. We were concerned about the method's validity because of the difficulty of the task, and its critical reliance on certain statistical assumptions. To allow us to test the validity of the method, Cruse and colleagues graciously supplied their data and analysis software.
Source: LANCET - January 25, 2013 Category: Journals (General) Authors: Andrew M Goldfine, Jonathan C Bardin, Quentin Noirhomme, Joseph J Fins, Nicholas D Schiff, Jonathan D Victor Tags: Correspondence Source Type: research
Biomechanical Evaluation of Undersized Drilling on Implant Biomechanical Stability at Early Implantation Times
Conclusions: Different drilling dimensions resulted in variations in insertion torque values (primary stability) and stability maintenance over the first weeks of bone healing.
Source: Journal of Oral and Maxillofacial Surgery - January 25, 2013 Category: ENT & OMF Authors: Paulo G. Coelho, Charles Marin, Hellen S. Teixeira, Felipe E. Campos, Julio B. Gomes, Fernando Guastaldi, Rodolfo B. Anchieta, Lucas Silveira, Estevam A. Bonfante Tags: Dental Implants Source Type: research
Long-Term Results of Implants Immediately Placed Into Extraction Sockets Grafted With β-Tricalcium Phosphate: A Retrospective Study
Conclusion: The use of TCP (Cerasorb) as a grafting material during immediate implant placement allowed no bone loss in 72.1% of the implants, which was very similar to the nongrafted cases for which implants were placed in favorable conditions.
Source: Journal of Oral and Maxillofacial Surgery - January 25, 2013 Category: ENT & OMF Authors: Noga Harel, Ofer Moses, Adi Palti, Zeev Ormianer Tags: Dental Implants Source Type: research
Identifying the translational gap in the evaluation of drug‐induced QTc‐interval prolongation
ConclusionsOur findings indicate that the slope of PKPD relationship in conscious dogs may be used as basis for the prediction of drug‐induced QTc prolongation in humans. Furthermore, the risk for QTc prolongation can be expressed in terms of the probability associated with an increase > 10 ms, allowing direct inferences about the clinical relevance of the pro‐arrhythmic potential of a molecule.
Source: British Journal of Clinical Pharmacology - January 25, 2013 Category: Drugs & Pharmacology Authors: ASY Chain, VFS Dubois, M Danhof, MCJM Sturkenboom, O Della Pasqua, Tags: Translational Research Source Type: research
In vivo comparison between laser‐treated and grit blasted/acid etched titanium
ConclusionLaser surface treatment gives the same results to the grit‐blasting/acid‐etched method and thus is a valid alternative to conventional roughening for dental implant materials.
Source: Clinical Oral Implants Research - January 25, 2013 Category: Dentistry Authors: Ljupcho Prodanov, Edwin Lamers, Joop Wolke, Richard Huiberts, John A. Jansen, X. Frank Walboomers Tags: Original Article Source Type: research
Ex vivo evaluation of various instrumentation techniques and irrigants in reducing E. faecalis within root canals
ConclusionsNo significant differences in terms of reduction in microbial counts were observed between single‐file techniques (SAF and Reciproc) and serial Ni‐Ti instrumentation technique (ProTaper) in combination with irrigants.© 2013 International Endodontic Journal. Published by Blackwell Publishing Ltd
Source: International Endodontic Journal - January 25, 2013 Category: Dentistry Authors: F Basmaci, M D. Öztan, M Kiyan Tags: Original Scientific Article Source Type: research
Collateral ligament injury in the displaced radial head and neck fracture: correlation with fracture morphology and management strategy to the torn ulnar collateral ligament
Background: The purpose of our study was to correlate the morphology of displaced radial head and neck (DRHN) fractures with associated ligament injuries and evaluate the outcomes of management of the torn ulnar collateral ligament (UCL).Methods: Twenty-nine surgically treated patients presenting with a DRHN fracture were classified using the Charalambous classification by 3-dimensional computed tomography. Accordingly, the collateral ligament and overlying muscle injuries and bony contusions were investigated with magnetic resonance imaging. The valgus stress test was performed intraoperatively on 20 patients with magneti...
Source: Journal of Shoulder and Elbow Surgery - January 25, 2013 Category: Orthopaedics Authors: In Hyeok Rhyou, Kyung Chul Kim, Kang Wook Kim, Ji-Ho Lee, Seung Yeon Kim Tags: Elbow Source Type: research
When does combining markers improve classification performance and what are implications for practice?
When an existing standard marker does not have sufficient classification accuracy on its own, new markers are sought with the goal of yielding a combination with better performance. The primary criterion for selecting new markers is that they have good performance on their own and preferably be uncorrelated with the standard. Most often linear combinations are considered. In this paper, we investigate the increment in performance that is possible by combining a novel continuous marker with a moderately performing standard continuous marker under a variety of biologically motivated models for their joint distribution. We fi...
Source: Statistics in Medicine - January 25, 2013 Category: Statistics Authors: Aasthaa Bansal, Margaret Sullivan Pepe Tags: Research Article Source Type: research
Completing the Catalog
Despite the widely held belief that the number of taxonomists is decreasing, there is evidence that increasing numbers of authors are describing species new to science. In parallel, several statistically … [Read more]
Source: This Week in Science - January 25, 2013 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research
Insufficient evidence to determine the impact of patient preferences on clinical outcomes in acupuncture trials: a systematic review
Conclusion: There is little evidence that preferences cause detectable effects on outcomes in acupuncture trials; however, trials use inconsistent methods and poorly report these data. Monitoring the level and effect of preferences in trials is recommended.
Source: Journal of Clinical Epidemiology - January 25, 2013 Category: Epidemiology Authors: Stephanie L. Prady, Jane Burch, Simon Crouch, Hugh MacPherson Tags: Original Articles Source Type: research
Citation bias favoring statistically significant studies was present in medical research
Conclusion: A citation bias favoring significant results occurs in medical research. As a consequence, treatments may seem more effective to the readers of medical literature than they really are.
Source: Journal of Clinical Epidemiology - January 25, 2013 Category: Epidemiology Authors: Anne-Sophie Jannot, Thomas Agoritsas, Angèle Gayet-Ageron, Thomas V. Perneger Tags: Original Articles Source Type: research
Postinterventional Pain and Complications of Sonographically Guided Interventions in the Liver and Pancreas.
Conclusion: Severe pain after sonographically guided interventions is rare. Most patients suffer only from mild pain postinterventionally. PMID: 23354721 [PubMed - as supplied by publisher]
Source: Ultraschall in der Medizin - January 25, 2013 Category: Radiology Authors: Lindner A, Frieser M, Heide R, Wildner D, Neurath MF, Dauth W, Bernatik T, Strobel D Tags: Ultraschall Med Source Type: research
Car driving in schizophrenia: can visual memory and organization make a difference?
Conclusion: The research demonstrates that impairment of visual abilities does not prevent people with schizophrenia from driving and emphasizes the importance of general cognitive status for complex and multidimensional everyday tasks. The findings support the need for further investigation in the field of car driving for this population - a move that will considerably contribute to the participation and well-being. Implication for Rehabilitation Unique approach for driving evaluation in schizophrenia should be designed since direct applications of knowledge and practice acquired from other populations are not reliable...
Source: Disability and Rehabilitation - January 25, 2013 Category: Rehabilitation Authors: Lipskaya-Velikovsky L, Kotler M, Weiss P, Kaspi M, Gamzo S, Ratzon N Tags: Disabil Rehabil Source Type: research
No effect of fibrin sealant on drain output or functional recovery following simultaneous bilateral total knee arthroplasty.
Abstract Background and purpose Blood loss after total knee arthroplasty (TKA) may lead to anemia, blood transfusions, and increased total costs. Also, bleeding into the periarticular tissue may cause swelling and a reduction in quadriceps strength, thus impairing early functional recovery. In this randomized, double-blind, placebo-controlled study, we analyzed the possible effect of fibrin sealant on blood loss and early functional recovery in a fast-track setting. Methods 24 consecutive patients undergoing bilateral simultaneous TKA were included. 10 mL of fibrin sealant (Evicel) was sprayed onto one knee wherea...
Source: Acta Orthopaedica - January 25, 2013 Category: Orthopaedics Authors: Skovgaard C, Holm B, Troelsen A, Lunn TH, Gaarn-Larsen L, Kehlet H, Husted H Tags: Acta Orthop Source Type: research
Correlation dimension estimates of human postural sway.
In this study we have started applying ergodic theory of dynamical systems to explore statistical characteristic of the sway dynamics observed in successive trials of a subject, different subjects in an age group, and finally different age groups constituted by children, adults, and elderly subjects. Five successive 180-s long trials were performed by each of 28 subjects in four age groups at quiet stance with eyes open. Stationary and ergodic signal characteristics of five successive center of pressure time series collected from a subject in antero-posterior direction (CoP(x)) were examined. 97% of the trials were found t...
Source: Human Movement Science - January 25, 2013 Category: Neurology Authors: Gurses S, Celik H Tags: Hum Mov Sci Source Type: research
Flexible‐Dose Fesoterodine in Elderly Adults with Overactive Bladder: Results of the Randomized, Double‐Blind, Placebo‐Controlled Study of Fesoterodine in an Aging Population Trial
ConclusionFesoterodine was associated with significantly greater improvements in most diary variables and participant‐reported outcomes than placebo and was generally well tolerated in older people.
Source: Journal of the American Geriatrics Society - January 25, 2013 Category: Geriatrics Authors: Adrian Wagg, Vik Khullar, Daniela Marschall‐Kehrel, Martin C. Michel, Matthias Oelke, Amanda Darekar, Caty E. Bitoun, David Weinstein, Ian Osterloh Tags: Clinical Investigations Source Type: research
Frailty and Fracture, Disability, and Falls: A Multiple Country Study From the Global Longitudinal Study of Osteoporosis in Women
ConclusionGreater evidence of a frailty phenotype is associated with greater risk of fracture, disability, and falls in women aged 55 and older in 10 countries, with similar patterns across age and geographic region.
Source: Journal of the American Geriatrics Society - January 25, 2013 Category: Geriatrics Authors: Sarah E. Tom, Jonathan D. Adachi, Frederick A. Anderson, Steven Boonen, Roland D. Chapurlat, Juliet E. Compston, Cyrus Cooper, Stephen H. Gehlbach, Susan L. Greenspan, Frederick H. Hooven, Jeri W. Nieves, Johannes Pfeilschifter, Christian Roux, Stuart Sil Tags: Clinical Investigations Source Type: research
Virological failure of staggered and simultaneous treatment interruption in HIV patients who began Efavirenz-based regimens after allergic reactions to nevirapine.
CONCLUSIONS: Among the patients who had an acute allergic reaction to first-line NVP-based therapy and later began an EFV-based regimen, virological outcomes resulting from a staggered interruption of treatment (with a continuation of NRTI backbone therapy for 7 days after discontinuing NVP) did not differ from those of the patients who began an EFV-based regimen as their initial therapy (Control). However, the virological failure of Simultaneous Interruption was possibly higher than those of Control and Staggered Interruption. PMID: 23347647 [PubMed - as supplied by publisher]
Source: AIDS Research and Therapy - January 25, 2013 Category: Infectious Diseases Authors: Siripassorn K, Manosuthi W, Pakdee A, Natprom S, Chaovavanich A, Hengphadpanadamrong N, Woratanarat K, Lueangniyomkul A, Ruxrungtham K Tags: AIDS Res Ther Source Type: research
Editorial statistics and best reviewers award for 2012.
PMID: 23328450 [PubMed - in process]
Source: Circulation Journal - January 25, 2013 Category: Cardiology Authors: Shimokawa H Tags: Circ J Source Type: research
The Association of Preoperative Statin Use and Acute Kidney Injury After Noncardiac Surgery.
CONCLUSIONS:Our data did not support the hypothesis that preoperative statin therapy in doses routinely used to treat hypercholesterolemia is associated with a change in the incidence of AKI, postoperative dialysis, or hospital mortality in patients undergoing noncardiac surgery. PMID: 23354338 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - January 25, 2013 Category: Anesthesiology Authors: Argalious MY, Dalton JE, Sreenivasalu T, O'Hara J, Sessler DI Tags: Anesth Analg Source Type: research
Early-stage microvascular alterations of a new model of controlled cortical traumatic brain injury: 3D morphological analysis using scanning electron microscopy and corrosion casting.
Conclusions The corrosion casting-SEM technique applied to a CCI experimental model proved to be a reliable method for studying the pathophysiology of the vascular alterations occurring at acute and subacute stages after CCI injury. It was also possible to obtain topographical localization of the vascular and cellular events that usually lead to hyperemia, edema, and brain swelling. Moreover, by applying informatic software to anatomical images it was possible to perform quantification and statistical analysis of the observed events. PMID: 23350772 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 25, 2013 Category: Neurosurgery Authors: Sangiorgi S, De Benedictis A, Protasoni M, Manelli A, Reguzzoni M, Cividini A, Dell'orbo C, Tomei G, Balbi S Tags: J Neurosurg Source Type: research
Virulence determinants and biofilm production among Trueperella pyogenes recovered from abscesses of captive forest musk deer.
In conclusion, the current study demonstrated that T. pyogenes was probably the primary pathogen of abscesses in the forest musk deer. Moreover, as an animal origin pathogen, the increasing resistance of T. pyogenes isolates could also associate with a decreased virulence. PMID: 23354327 [PubMed - as supplied by publisher]
Source: Archives of Microbiology - January 25, 2013 Category: Microbiology Authors: Zhao K, Tian Y, Yue B, Wang H, Zhang X Tags: Arch Microbiol Source Type: research
Block Allograft Technique versus Standard Guided Bone Regeneration: A Randomized Clinical Trial
ConclusionsThe block allograft and the standard regenerative procedure showed similar results in terms of regenerated bone volume after 1 year of functional loading. The rhPDGF‐BB positively influenced soft‐tissue healing.
Source: Clinical Implant Dentistry and Related Research - January 25, 2013 Category: Dentistry Authors: Leonardo Amorfini, Marco Migliorati, Alessio Signori, Armando Silvestrini‐Biavati, Stefano Benedicenti Tags: Original Article Source Type: research
Prognostic Validity of the American Joint Committee on Cancer Staging Classification for Midgut Neuroendocrine Tumors [Gastrointestinal Cancer]
Conclusion Stage I and II midgut NETs are associated with identical survival rates. Stage IIIB tumors are heterogeneous, with significant differences in survival observed between resectable mesenteric lymph nodes versus unresectable masses in the root of the mesentery. A higher mitotic cutoff of five per 10 HPF may lead to improved prognostic differentiation between low- and intermediate-grade tumors. Revisions to the current AJCC staging and grading classification may be warranted.
Source: Journal of Clinical Oncology - January 25, 2013 Category: Cancer & Oncology Authors: Strosberg, Weber, Feldman, Coppola, Meredith, Kvols Tags: Diagnosis & Staging, Diagnosis & Staging Gastrointestinal Cancer Source Type: research
Independent evaluation of low‐level laser therapy at 635 nm for non‐invasive body contouring of the waist, hips, and thighs
ConclusionThese data further validate the clinical efficacy and safety of LLLT at 635 nm. Lasers Surg. Med. 45: 1–7, 2013. © 2013 Wiley Periodicals, Inc.
Source: Lasers in Surgery and Medicine - January 25, 2013 Category: Laser Surgery Authors: Elizabeth McRae, Jaime Boris Tags: Clinical Report Source Type: research
Resection of hepatocellular cancer ≤2 cm: Results from two Western centers
Conclusion: Resection of HCC ≤2 cm is safe and achieves excellent results in Western centers. Recurrence continues to be a significant problem. Presence of satellites, platelet count, anatomic resection, and cirrhosis are associated with outcomes after resection, even among such early tumors. Resection should continue to be considered a primary treatment modality in patients with small HCC and well‐preserved liver function. (HEPATOLOGY 2013)
Source: Hepatology - January 25, 2013 Category: Internal Medicine Authors: Sasan Roayaie, Khaled Obeidat, Carlo Sposito, Luigi Mariani, Sherrie Bhoori, Alessandro Pellegrinelli, Daniel Labow, Josep M. Llovet, Myron Schwartz, Vincenzo Mazzaferro Tags: Hepatobiliary Malignancies Source Type: research
Ecological correlates of the distribution limits of two poeciliid species along a salinity gradient
Identifying the environmental factors responsible for the formation of a species' distribution limit is challenging because organisms interact in complex ways with their environments. However, the use of statistical niche models in combination with the analysis of phenotypic variation along environmental gradients can help to reduce such complexity and identify a subset of candidate factors. In the present study, we used such approaches to describe and identify factors responsible for the parapatric distribution of two closely‐related livebearer fish species along a salinity gradient in the lowlands of Trinidad, West Ind...
Source: Biological Journal of the Linnean Society - January 25, 2013 Category: Research Authors: Julián Torres‐Dowdall, Felipe Dargent, Corey A. Handelsman, Indar W. Ramnarine, Cameron K. Ghalambor Tags: Research Article Source Type: research
Association of thymidylate synthase gene 3'-untranslated region polymorphism with sensitivity of non-small cell lung cancer to pemetrexed treatment: TS gene polymorphism and pemetrexed sensitivity in NSCLC
Conclusions: This study showed that TS protein is highly expressed in NSCLC and that polymorphisms of TS 3'-UTR 1494del 6 bp are associated with sensitivity of lung adenocarcinoma patients to pemetrexed treatment. This suggests that TS gene polymorphisms should be further evaluated as prognostic markers for personalized therapy in lung adenocarcinoma.
Source: BioMed Central - January 25, 2013 Category: Journals (General) Authors: Xia WangYadi WangYue WangJian ChengYanyun WangMinwen Ha Source Type: research
The Natural History and Long‐term Outcomes in Patients with Chronic Hepatitis C Genotype 4 after Interferon‐based Therapy
ConclusionsThis study describes, for the first time, the natural history and demonstrates the beneficial long‐term effects of interferon‐based therapy in HCV G4 patients.© 2013 John Wiley & Sons A/S
Source: Liver International - January 25, 2013 Category: Gastroenterology Authors: F.Z. Alfaleh, K. Alswat, A. Helmy, W. Al‐hamoudi, M. El‐sharkawy, M. Omar, A. Shalaby, M.A. Bedewi, Q. Hadad, S. M Ali, A. Alfaleh, AA. Abdo Tags: Original Article Source Type: research
Can lower aldehyde dehydrogenase activity in saliva be a risk factor for oral cavity cancer?
ConclusionLow salivary ALDH activity may be a risk factor for oral cancer development.
Source: Oral Diseases - January 25, 2013 Category: ENT & OMF Authors: J Giebułtowicz, P Wroczyński, D Samolczyk‐Wanyura Tags: Original Article Source Type: research
Graft incorporation and implant osseointegration following the use of autologous and fresh‐frozen allogeneic block bone grafts for lateral ridge augmentation
ConclusionAllogeneic bone block grafts may be an option in cases where a limited amount of augmentation is needed, and the future implant can be expected confined within the inner aspect of the bone block. However, the clinical impact of the relatively poor graft incorporation on the long‐term performance of oral implants placed in AL grafts remains obscure.
Source: Clinical Oral Implants Research - January 25, 2013 Category: Dentistry Authors: Rubens Spin‐Neto, Andreas Stavropoulos, Felipe Leite Coletti, Rafael Silveira Faeda, Luís Antônio Violin Dias Pereira, Elcio Marcantonio Tags: Original Article Source Type: research
Effect of melatonin on chronic bladder‐ischaemia‐associated changes in rat bladder function
Conclusions Arterial occlusive disease may lead to chronic bladder ischaemia and bladder hyperactivity associated with oxidative stress. In the model used, chronic treatment with melatonin protected bladder function and morphology, probably through its free radical scavenging and antioxidative properties. Melatonin may prevent oxidative damage and improve ischaemia‐related bladder dysfunction.
Source: BJU International - January 25, 2013 Category: Urology & Nephrology Authors: Masanori Nomiya, David Mark Burmeister, Norifumi Sawada, Lysanne Campeau, Mona Zarifpour, Osamu Yamaguchi, Karl‐Erik Andersson Tags: Translational Science Source Type: research
Multiple cores of Gleason score 6 correlate with favourable findings at radical prostatectomy
Conclusion A low Gleason score on biopsy is a powerful prognostic finding, such that this favourable outcome is maintained even in the setting of multiple positive cores with GS6.
Source: BJU International - January 25, 2013 Category: Urology & Nephrology Authors: Carla L. Ellis, Patrick C. Walsh, Alan W. Partin, Jonathan I. Epstein Tags: Urological Oncology Source Type: research
Many young men with prostate‐specific antigen (PSA) screen‐detected prostate cancers may be candidates for active surveillance
Conclusions Nearly half of young men with PSA screen‐detected prostate cancer are AS candidates but the overwhelming majority seek treatment. Considering that many tumours show favourable pathology at RP, there is a possibility that these patients may benefit from AS management.
Source: BJU International - January 25, 2013 Category: Urology & Nephrology Authors: Jeri Kim, James Ebertowski, Matthew Janiga, Jorge Arzola, Gayle Gillespie, Michael Fountain, Douglas Soderdahl, Edith Canby‐Hagino, Sally Elsamanoudi, Jennifer Gurski, John W. Davis, Patricia A. Parker, Douglas D. Boyd Tags: Urological Oncology Source Type: research
Long‐term outcome of small, organ‐confined renal cell carcinoma (RCC) is not always favourable
Conclusions Patients with MVI have worse survival than those without MVI. This suggests that long‐term follow‐up of patients with small RCCs is needed because of the risk of recurrence and cancer death even 10 years after surgery, particularly when the disease has apparent MVI.
Source: BJU International - January 25, 2013 Category: Urology & Nephrology Authors: Tetsuya Shindo, Naoya Masumori, Ko Kobayashi, Fumimasa Fukuta, Megumi Hirobe, Akiko Tonooka, Tadashi Hasegawa, Hiroshi Kitamura, Taiji Tsukamoto Tags: Urological Oncology Source Type: research
Osteoporosis knowledge, health beliefs, and healthy bone behaviours in patients on androgen‐deprivation therapy (ADT) for prostate cancer
Conclusions Most patients who are receiving ADT are not receiving appropriate screening, lack basic information about bone health, and are not engaging in the appropriate HBBs. These findings support the application of the Health Belief Model in this population: interventions that teach patients about the implications of bone loss, encourage proper uptake of HBBs, and promote feelings of SE could increase engagement in HBBs to prevent and manage bone loss.
Source: BJU International - January 25, 2013 Category: Urology & Nephrology Authors: Michelle Nadler, Shabbir Alibhai, Pamela Catton, Charles Catton, Matthew J. To, Jennifer M. Jones Tags: Urological Oncology Source Type: research
Docking of the da Vinci Si Surgical System® with single‐site technology
ConclusionThe docking process for a robotic single‐incision cholecystectomy is learned rapidly and does not significantly increase the overall OR time. Copyright © 2013 John Wiley & Sons, Ltd.
Source: The International Journal of Medical Robotics and Computer Assisted Surgery - January 25, 2013 Category: Surgery Authors: Pouya Iranmanesh, Philippe Morel, Nicolas C. Buchs, François Pugin, Francesco Volonte, Usha Seshadri Kreaden, Monika E. Hagen Tags: Original Article Source Type: research
Virological failure of staggered and simultaneous treatment interruption in HIV patients who began Efavirenz-based regimens after allergic reactions to nevirapine
Conclusions: Among the patients who had an acute allergic reaction to first-line NVP-based therapy and later began an EFV-based regimen, virological outcomes resulting from a staggered interruption of treatment (with a continuation of NRTI backbone therapy for 7 days after discontinuing NVP) did not differ from those of the patients who began an EFV-based regimen as their initial therapy (Control). However, the virological failure of Simultaneous Interruption was possibly higher than those of Control and Staggered Interruption.
Source: AIDS Research and Therapy - January 25, 2013 Category: Infectious Diseases Authors: Krittaecho SiripassornWeerawat ManosuthiAranya PakdeeSunanta NatpromAnuttra ChaovavanichNarongsak HengphadpanadamrongKhobchok WoratanaratAroon LueangniyomkulKiat Ruxrungtham Source Type: research
Higher protein diet for weight management in young overweight women: a 12‐month randomized controlled trial
Clinical research on weight management in young women is limited. This randomized controlled trial compared the efficacy of two iso‐energetically restricted (5600 kJ) diets [higher protein (HP): 32% protein, 41% carbohydrate, 25% fat or higher carbohydrate (HC): 20, 58, 21%, respectively] in 71 (HP: n = 36; HC: n = 35) young healthy women (18–25 years; body mass index ≥ 27.5 kg/m2) for weight (kg; percent weight loss), body composition, metabolic and iron changes assessed at baseline, 6 and 12 months. Data: mean (95% CI). In HP completers at 6 months, percent weight loss was higher [HP: 9.3 (5.6–13.1)...
Source: Diabetes, Obesity and Metabolism - January 25, 2013 Category: Endocrinology Authors: H. J. Griffin, H. L. Cheng, H. T. O'Connor, K. B. Rooney, P. Petocz, K. S. Steinbeck Tags: RESEARCH LETTER Source Type: research
Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a meta-analysis of randomised controlled clinical trials
Conclusion Intracoronary BMC treatment leads to a moderate improvement of LVEF and reduction of LVESV at 6 months that sustained at 12 months follow-up, without a clear significant effect on LVEDV, or infarct size. Furthermore, we found that intracoronary cell therapy is significantly associated with a reduction in recurrent AMI and readmission for heart failure, unstable angina or chest pain.
Source: Heart - January 25, 2013 Category: Cardiology Authors: Delewi, R., Andriessen, A., Tijssen, J. G. P., Zijlstra, F., Piek, J. J., Hirsch, A. Tags: Reviews Source Type: research
Comparison of contact angle hysteresis of different probe liquids on the same solid surface.
Abstract Advancing and receding contact angles of water, formamide and diiodomethane were measured on 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) layers deposited on three different solid supports-glass, mica and poly(methyl methacrylate). Up to five statistical monolayers were deposited on the surfaces by spreading DPPC solution. It was found that even on five statistical DPPC monolayers, the hysteresis of a given liquid depends on the kind of solid support. Also on the same solid support the contact angle hysteresis is different for each probe liquid used. The AFM images show that the heights of roughness ...
Source: Colloid and Polymer Science - January 24, 2013 Category: Biotechnology Authors: Chibowski E, Jurak M Tags: Colloid Polym Sci Source Type: research
Robust calibrations on reduced sample sets for API content prediction in tablets: Definition of a cost-effective NIR model development strategy.
Abstract Owing to spectral variations from other sources than the component of interest, large investments in the NIR model development may be required to obtain satisfactory and robust prediction performance. To make the NIR model development for routine active pharmaceutical ingredient (API) prediction in tablets more cost-effective, alternative modelling strategies were proposed. They used a massive amount of prior spectral information on intra- and inter-batch variation and the pure component spectra to define a clutter, i.e., the detrimental spectral information. This was subsequently used for artificial data ...
Source: Analytica Chimica Acta - January 24, 2013 Category: Chemistry Authors: Pieters S, Saeys W, Van den Kerkhof T, Goodarzi M, Hellings M, De Beer T, Heyden YV Tags: Anal Chim Acta Source Type: research
A tutorial on the application of ion-selective electrode potentiometry: An analytical method with unique qualities, unexplored opportunities and potential pitfalls; Tutorial.
Abstract Ion-selective potentiometry enjoys practical utility as a simple analytical technique to measure ionic constituents in complex samples. Advances in the field have improved the selectivity and decreased the detection limit of ion-selective electrodes (ISEs) by orders of magnitude such that trace analysis in micro and nanomolar concentrations is now possible with potentiometric sensors. This tutorial reviews the fundamental principles of ion-selective potentiometry, describes the practical considerations involved in the use of these sensors to measure real samples, and discusses the statistical evaluation of...
Source: Analytica Chimica Acta - January 24, 2013 Category: Chemistry Authors: Lindner E, Pendley BD Tags: Anal Chim Acta Source Type: research
The influence of folate supplementation on global gene expression in normal colonic mucosa of subjects with colorectal adenoma
ConclusionThese results indicate that while folic acid can modify gene expression, it is difficult to separate its effects from the natural variability in gene expression in the colon.
Source: Nahrung / Food - January 24, 2013 Category: Nutrition Authors: Maria Pufulete, Reyad Al‐Ghnaniem Abbadi, Matthew Arno, Mark Ewins, Caroline Green, Estibaliz Aldecoa‐Otalora Astarloa, Tom Sanders, Peter Emery Tags: Research Article Source Type: research
Cigarette smoking and subsequent risk of suicidal ideation among National Guard Soldiers
Conclusions: Army National Guard soldiers who smoke have a greater risk of subsequent suicidal ideation. Depression concurrent with suicidal ideation appears to explain this relationship. If these results are replicated, screening of soldiers who smoke may be recommended as a proactive step towards mitigating the high risk of suicide in military personnel.
Source: Journal of Affective Disorders - January 24, 2013 Category: Neurology Authors: Renee D. Goodwin, Marta R. Prescott, Marijo Tamburrino, Joseph R. Calabrese, Israel Liberzon, Sandro Galea Tags: Preliminary Communication Source Type: research
Do alcohol use disorders destabilize the course of bipolar disorder?
Conclusions: Although alcohol does not seem to affect time to mood episode remission, alcohol use destabilizes the course of illness over the long run as evidenced by associations with more rapid cycling and mood episode recurrence.
Source: Journal of Affective Disorders - January 24, 2013 Category: Neurology Authors: Jeffrey J. Rakofsky, Boadie W. Dunlop Tags: Reviews Source Type: research
The relation of serum nesfatin‐1 level with metabolic and clinical parameters in obese and healthy children
ConclusionsThis is the first study to evaluate nesfatin‐1 levels in relation with anthropometric and metabolic parameters in obese patients who had significantly lower nesfatin‐1 levels. Our results underline that nesfatin‐1 may play an important role in regulation of food intake in obese individuals.
Source: Pediatric Diabetes - January 24, 2013 Category: Endocrinology Authors: Ayhan Abaci, Gonul Catli, Ahmet Anik, Tuncay Kume, Ece Bober Tags: Original Article Source Type: research
Derivation of stochastic differential equations for scrape-off layer plasma fluctuations from experimentally measured statistics
A. Mekkaoui A stochastic differential equation for intermittent plasma density dynamics in magnetic fusion edge plasma is derived, which is consistent with the experimentally measured gamma distribution and the theoretically expected quadratic nonlinearity. The plasma density is driven by a multiplicative Wiene ... [Phys. Plasmas 20, 010701 (2013)] published Wed Jan 23, 2013.
Source: Physics of Plasmas - January 24, 2013 Category: Physics Source Type: research