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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 19.

Can Insurance Pre-Authorization Ensure High Quality Melanoma Care? Development of a Simple Algorithm to Verify the Surgical Treatment Plan
The objectives of this study were (1) to develop a simple algorithm to predict guideline-based melanoma treatment; (2) to determine the accuracy and potential causes of failure of the algorithm; and (3) to develop electronic medical record and online interfaces to facilitate provider reporting and potential payer preauthorization.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: B.S. Kester, J.D. Wayne, D.J. Bentrem, R.P. Merkow, K.Y. Bilimoria Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

A Short-Stay Unit for the Post-Operative Care of Thyroidectomy Patients Increases Discharge Efficiency
Patients traditionally recover overnight on a general surgery ward after a thyroidectomy. While these units usually recover patients after major operations, they often lack the efficiency and focus for rapid discharge which is the goal of a short-stay unit. Utilizing a short-stay unit for thyroidectomy patients, who are often discharged in
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: S.M. Vrabec, N. Clark, S.C. Oltmann, H. Chen, R.S. Sippel Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

Ethanol Consumption Improves Insulin Signaling In Chronically Ischemic Myocardium
There is growing evidence that glycemic control after cardiac surgery is important to improve postoperative outcomes. In addition to glycemic control, low to moderate doses of alcohol has been shown to reduce the risk of cardiovascular disease and diabetes compared to abstainers. Although it is not well understood, alcohol mediates its cardioprotective and anti-diabetic effects via the insulin signaling pathway. Previously, we demonstrated that swine with metabolic syndrome treated with alcohol had improved insulin sensitivity. We developed a follow-up study to evaluate the effects of alcohol on ischemic myocardium in anim...
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: N.Y. Elmadhun, A.D. Lassaletta, B. Thomas, A. Sabe, F.W. Sellke Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

Differential Regulation of The Inflammatory Response During Fetal Cardiac Regeneration Following Myocardial Infarction (MI)
Despite modern medical advances, the mortality from heart failure following myocardial infarction (MI) has not changed since the 1950’s. We have shown that the fetal response to MI is very different than the adult. The fetal response results in regeneration of myocardium and restoration of cardiac functionand is associated with rapid resolution of the inflammatory response. In contrast, the adult response to MI results in infarct expansion, a progressive loss of function, and is associated with a persistent inflammatory response. Inflammation isregulated by the production of cytokines, such as tumor necrosis factor alpha...
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: M.W. Morris, M. Allukian, J. Xu, R.C. Caskey, W. Dorsett-Martin, M.E. Mitchell, J.H. Gorman, R.C. Gorman, K.W. Liechty Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

Autologous CD117+ Mesenchymal Stem Cell Injections Provide Superior Therapeutic Benefit as Compared to CD117+ Cardiac-Derived Stem Cells in a Feline Model of Isoproterenol Induced Cardiomyopathy
This study is the first to compare autologous CD117+ CSC and CD117+ MSC treatment after myocardial injury in a large animal model.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: S. Taghavi, T.A. Sharp, J.M. Duran, C.A. Makarewich, S. Khoche, R.M. Berretta, T. Starosta, H. Kubo, M. Barbe, S.R. Houser Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

The CD8+/TCR- Facilitating Cell Population is Comprised of Distinct Cellular Subsets that Exhibit Differential Cytokine Expression: Implications in the Enhancement of Allogeneic Stem Cell Engraftment
In this study, we explore the differential cytokine expression of both the pTC and pDC subpopulations derived from CD8+/TCR- FC.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: M.J. Schuchert, A.L. Opest, R.J. Landreneau, J.D. Luketich, N.N. Gangopadhyay Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

Impact of Donor Cardiac Arrest on Heart Transplantation
Cardiac transplantation is an effective therapy for patients with end-stage heart failure with 1, 5, and 10-year survival figures approaching 80%, 65%, and 43% respectively {Yeatman M et al 1995}. However, this successful therapy is still hindered by a lack of donor organs. In fact, only one in four consented donors are used for heart transplantation {Stehlik et al. 2010}. Undoubtedly, a history of donor cardiac arrest raises genuine trepidation regarding the possibility of poor post-transplant outcomes, such as overall survival and primary graft dysfunction. These concerns are legitimate considering that a history of card...
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: K.W. Southerland, A. Castleberry, M. Mack, J. Williams, M. Daneshmand, C.A. Milano Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

Cardiac Transplantation Can Be Safely Performed Using Diabetic Donors
In this study, we attempt to determine if adult OHT can be safely performed using DD.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: S. Taghavi, S.N. Jayarajan, L. Wilson, E. Komaroff, A.A. Mangi Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

Impact of Extra-Corporeal Membrane Oxygenation or Mechanical Ventilation as Bridge to Combined Heart-Lung Transplantation on Short- and Long-Term Survival
Extracorporeal membrane oxygenation (ECMO) and mechanical ventilation (MV) can be used as a bridge to heart-lung transplantation (HLT). However, few studies have evaluated the impact of these interventions on survival in HLT. The goal of this study was to determine if pre-transplant ECMO or mechanical ventilation affects survival in HLT.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: S.N. Jayarajan, S. Taghavi, E. Komaroff, S. Brann, T. Horai, S. Guy, Y. Toyoda Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

Cardiac Transplantation can be Safely Performed Using Low Donor to Recipient Body Weight Ratios
UNOS criteria for adult heart transplantation (HT) suggest not using donors that have a donor to recipient body weight ratio (WR) of less than 0.8. For female to male transplants, a WR of no less than 0.9 is recommended. We attempt to determine if criteria for WR can be safely extended.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: S.N. Jayarajan, S. Taghavi, L. Wilson, E. Komaroff, A.A. Mangi Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

Cardiac Transplantation With ABO Compatible Donors Has Equivalent Long-Term Survival
In this study, we attempt to determine if adult OHT can be safely performed using ABO compatible donors (ACD).
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: S. Taghavi, S.N. Jayarajan, L. Wilson, E. Komaroff, A.A. Mangi Tags: Oral Session: Wednesday 2/6 7:30 AM to 9:30 AM Source Type: research

Velaparib (ABT-888), A Novel Inhibitor of Poly-Adp Ribosyl Polymerase (PARP), Synergizes with 5-Fluorouracil in Pancreatic Carcinoid Cells
5-Fluorouracil (5-FU) exerts anti-cancer effects by genomically incorporating 5-FU thereby disrupting DNA replication. Notably, cancer cells may evade DNA damage through base excision repair (BER), during which DNA lesions are excised, recruiting poly(ADP-ribose) polymerase (PARP) and scaffolding proteins that re-insert the correct base pair allowing for normal cell division to continue. Recent studies suggest that silencing BER pathway components like PARP using small interfering RNAs or small molecule agents may potentiate DNA damaging agents such as 5-FU. Here, we demonstrate that ABT-888, a novel inhibitor of PARP, che...
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: Y.R. Somnay, S. Lubner, M. Kunnimalaiyaan, H. Chen Source Type: research

NSQIP and NIS Under-report Adverse Events in Appendicitis
Appendectomy is the most common general surgical operation in the USA. Surgical site infection (SSI) is a common complication. Accurate reporting of SSI using established guidelines is critical. NSQIP gathers data prospectively using trained auditors conducting chart review. NIS is an administrative database where data is captured by ICD-9 codes relying on coding and billing records. Each database is established in an effort to assess and promote quality care. The purpose of this study is to compare reported SSI incidence in prospective randomized controlled trials (PRCTs) using CDC definition.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: P.C. Tran, M.K. Liang, U.R. Phatak, N.M. Tapia, L.S. Kao, J.W. Suliburk Source Type: research

Effect of Age and BMI on Mortality and Morbidity in Elective and Emergent General Surgery
The prevalence of obesity and morbid obesity in the United States has exponentially increased over the past several decades. In addition, the elderly population is expected to be the dominant age group by the year 2030 and today represents more than 12% of the total population. Obese elderly patients are increasingly undergoing elective and emergent general surgery. We aim to determine if there is a synergistic effect of Body Mass Index (BMI) and Age on morbidity and mortality in elective and emergent general surgery. We hypothesize that increasing age and BMI have a synergistically negative effect on morbidity and mortali...
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: F.J. Yanquez, D. Grauf, J. Clements, A. Merchant Source Type: research

Effect of Competitive Training on a Virtual Reality Simulator on Surgical Performance: A Randomized Controlled Trial
Increasing concerns regarding patient safety have suggested a need for alternative training methods outside the operating room. Despite increasing conversation centered on applying principles of sports training to surgery, few efforts have been made to fully elucidate the sports training strategies that would be most effective in surgical education. Competitive training has been successful in sport in improving performance, and this study investigates whether competitive training can enhance performance in laparoscopic surgery.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: D.A. Hashimoto, A. Khajuria, L. Beyer-Berjot, N.N. Williams, A. Darzi, R. Aggarwal Source Type: research

Blocking the P2X7 Receptor in a Rat Nerve-Injury Model Improves Long Term Functional Outcomes
Activation of the P2X7 Receptor causes the formation of pannexin pores. These holes allow for the efflux of ATP and the influx of calcium across the cell membrane. Activated P2X7 receptors have been shown to cause cell death in enteric and retinal ganglion cells. Polyethlyene glycol (PEG) and methylene blue (MB) have previously been suggested to delay Wallerian degeneration through a receptor-independent manner if applied during microsuture repair of the severed nerve. Calcium modulation is a critical part of the PEG based axonal repair because once calcium enters the axon, the cut nerve ends seal, preventing PEG based axo...
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: C.L. Rodriguez-Feo, K. Sexton, R.B. Boyer, A.O. Pollins, N.L. Cardwell, L.B. Nanney, B. Shack, W.P. Thayer Source Type: research

Outcomes for Patients with Emphysema Undergoing Surgical Resection of Stage I Non-small Cell Lung Cancer (NSCLC)
The determination of emphysema severity in patients with lung cancer undergoing surgical resection is currently under active investigation. We assessed the 5-year survival of patients with biopsy proven Stage I NSCLC stratified by a visual analog scale for the severity of emphysema.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: M. Bishawi, W.H. Moore, T. Bilfinger Source Type: research

SiRNA Transfection with Cholesterol Modification from Electrospun PET Facilitates Gene Silencing in Human Aortic Smooth Muscle Cells
Anastomotic intimal hyperplasia (AIH) remains the leading cause for prosthetic arterial graft failure. RNAi is a promising tool to silence genes such as Thrombospondin-2 (TSP-2), previously shown by our group to be upregulated in AIH. The present study is aimed at delivering modified TSP-2 siRNA (3’cholesterol tagged TSP-2 siRNA) from electrospun polyethylene terephthalate (ePET) and therefore knocking down TSP-2 gene and ultimately inhibiting AIH.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: M.C. Chun, H.S. Oliver-Allen, C.S. Nabzdyk, S.G. Pathan, M.D. Phaneuf, L. Pradhan-Nabzdyk, F.W. LoGerfo Source Type: research

Combination of Adoptive Cell Transfer with CTLA-4 Blockade Maximizes Melanoma Immunotherapy
The dearth of effective treatment options for advanced melanoma has prompted strong interest in the development of immune-based therapies. Adoptive cell transfer (ACT) of melanoma-specific T cells has shown benefit in limited clinical trials, and augmentation of T cell activity using antibodies against the T cell inhibitory receptor CTLA-4 has been shown to have survival benefit. We used a murine model of melanoma immunotherapy to test the hypothesis that combination immunotherapy using ACT with CTLA-4 blockade may have additive therapeutic benefit.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: D.A. Mahvi, L. Wentworth, J.V. Meyers, C.S. Cho Source Type: research

A MAPK Dependent Pathway Induces Epithelial Mesenchymal Transition (EMT) Via Twist Activation in Human Breast Cancer Cell Lines
Twist is a bHLH transcription factor involved in EMT to transform ectodermal cells into migratory mesenchymal cells during gastrulation. In cancer, EMT instigates cell invasion and migration, the beginnings of the metastatic cascade. Our research has shown osteopontin (OPN) regulates expression of critical EMT transcription factors, Snail, Slug, and Twist. However, the underlying signaling pathway is unknown. We hypothesized that OPN activates Twist in an autocrine manner to induce EMT in human breast cancer.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: N.Y. Li, C.E. Weber, P.Y. Wai, B. Cuevas, P.C. Kuo, Z. Mi Source Type: research

5-Lipoxygenase Inhibition Attenuates Intestinal Polyposis through Suppression of Inflammation
In this study, we hypothesize that an oral 5LO inhibitor, zileution, will attenuate inflammation and polyp growth.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: M.J. Heiferman, J.R. Heiferman, N.R. Blatner, J.D. Phillips, E.C. Cheon, L.M. Knab, E.A. Wayne, K. Khazaie, P.J. Grippo, D.J. Bentrem Source Type: research

Post-Treatment Surveillance in Locoregional Breast Cancer: Guideline Adherence and Patterns in Use of Non-Recommended Testing
Annual mammography and physical exam are currently recommended for the post-treatment surveillance of early stage breast cancer. The current utility of new and non-recommended tests such as dedicated breast MRI, computed tomography (CT) or magnetic resonance imaging (MRI) of the head, chest, and abdomen, or positron emission tomography (PET) is unknown. Objective: To use population-based data to describe current trends in use of recommended and non-recommended tests as surveillance modalities in older women following definitive operation for breast cancer.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: A.D. Parmar, K.M. Sheffield, G.M. Vargas, Y. Han, C. Chao, T.S. Riall Source Type: research

Measuring Postoperative Recovery after Elective Colorectal Resection: Validation of the SF-6D Health Utility Value
Many innovations in colorectal surgery, such as minimally invasive techniques and “fast track” pathways, are costly but may result in faster patient recovery. Economic analyses of these innovations require health state utility values, such as the Short Form-6D (SF-6D), to reflect the construct of “postoperative recovery” in order to calculate quality-adjusted life years and determine cost effectiveness. However it is unknown if the SF-6D is a valid measure of postoperative recovery. We investigated the validity of SF-6D utility value as a measure of postoperative recovery in patients undergoing elective colorectal resection.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: L. Lee, C. Li, N. Elfassy, S.A. Liberman, B. Stein, P. Charlebois, F. Carli, G.M. Fried, L.S. Feldman Source Type: research

Can Surgical Case Complexity be Better Captured? Effect of Secondary CPT Codes on Short-Term Outcome Models After Gastrointestinal Oncologic Operations
An increasing number of studies are using data from ACS NSQIP to assess postoperative outcomes. However, there is concern that additional oncologic case complexity is not captured by the primary CPT code. Our objectives were (1) to use secondary CPT codes to characterize additional complexity of a case, (2) to evaluate the effect of case complexity variables on 30-day outcomes and (3) to assess improvement in risk-predictions with their inclusion.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: R.P. Merkow, D.J. Bentrem, C.Y. Ko, K.Y. Bilimoria Source Type: research

Better Outcomes with Higher Volumes of Acute Care Surgical Procedures
Higher surgical volumes have been associated with improved outcomes after a number of surgical procedures. It is not known whether this is true for acute care surgical procedures where higher volumes might lead to increased pressure on limited resources or delays in treatment. Our objective was to explore the relationship between volume and outcome after selected acute care surgical procedures (ACSP).
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: E.C. Hall, S. Zafar, X. Hui, E.E. Cornwell, A.H. Haider Source Type: research

Quick Response (QR) Codes for Surgical Safety, Is it Ready for Prime Time? Results from a Prospective Pilot Study
The surgical safety checklist has been shown to reduce patient harm by improving communication through consistency and standardization. However, we and others have shown that implementation and compliance are variable which may be a direct result of checkbox fatigue. Introduction of innovative technology such as Quick Response (QR) codes may improve information transfer and positively impact compliance, accuracy and outcomes of the surgical safety process. The purpose of this study is to determine if QR codes can be used to facilitate surgical safety initiatives and to assess perceptions of its use by surgical team stakeho...
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: J.L. Dixon, W.R. Smythe, D.C. Jupiter, H.T. Papaconstantinou Source Type: research

Surgical Care Improvement Project Quality Measures and Surgical Site Infections: Can Integration into the Surgical Safety Checklist Improve Quality Compliance and Clinical Outcomes?
The World Health Organization Surgical Safety Checklist (SSCL) has been shown to decrease mortality and complications including perioperative surgical site infections (SSI). The Surgical Care Improvement Project (SCIP) contains several elements designed to improve surgical patient outcomes. We evaluated the impact of SCIP measure integration within our SSCL on quality compliance and SSI.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: M. Tillman, H. Wehbe-Janek, W.R. Smythe, H.T. Papaconstantinou Source Type: research

Risk Adjusted Analyses to Improve Trauma Care: Comparing a Simple Six Variable Model to the ? Gold Standard?
This study aims to compare a simple six covariate risk adjustment model to the risk adjustment methodology used by the American College of Surgeons Trauma Quality Improvement Program (TQIP) to benchmark trauma centers on mortality.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: Z.G. Hashmi, S. Zafar, E.B. Schneider, E.R. Haut, E.E. Cornwell, V.K. Scott, D.T. Efron, A.H. Haider Source Type: research

5-Lipoxygenase Inhibition Attenuates Intestinal Polyposis Through Suppression of Inflammation
In this study, we hypothesize that an oral 5LO inhibitor, zileution, will attenuate inflammation and polyp growth.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: M.J. Heiferman, J.R. Heiferman, N.R. Blatner, J.D. Phillips, E.C. Cheon, L.M. Knab, E.A. Wayne, K. Khazaie, P.J. Grippo, D.J. Bentrem Source Type: research

Organ Tissue Engineering Using Autologous Decellularized Microcirculatory Beds AS Vascularized Bioscaffolds
Advances in tissue engineering are hampered by the inability of artificial scaffolds to recapitulate complex microvascular structures. However, functional microvascular beds exist throughout the body, they are explantable and readily re-integrated into the systemic circulation (i.e. microvascular free flaps). In the current study we utilize these explantable microvascular beds (EMBs) as scaffolds for progenitor cell seeding as a novel approach to organ-level tissue engineering.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: L.H. Evers, W. Liu, D. Simons, M. Sorkin, M.T. Longaker, G.C. Gurtner Source Type: research

NLRP3 Inflammasome Activates Matrix Metalloproteinase-9: Potential Role in Smooth Muscle Cell Dysfunction in Thoracic Aortic Disease
Excessive matrix metalloproteinase (MMP) activity during inflammation disrupts aortic wall homeostasis, causing progression of thoracic aortic aneurysms and dissections (TAAD). The NLRP3-ASC-caspase-1 inflammasome complex is critically involved in the activation and secretion of inflammatory factors. However, the role of this complex in regulating MMP activity remains unknown. We hypothesize that the NLRP3 inflammasome complex activates MMP-9, leading to cleavage of contractile proteins, resulting in thoracic aortic smooth muscle cell (SMC) dysfunction.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: D. Wu, J.C. Choi, J. Coselli, Y.H. Shen, S.A. LeMaire Source Type: research

Tissue Engineered Small-Diameter Arterial Graft: In Vivo Evaluation of an Electrospun Nanofiber Scaffold
Use of synthetic vascular grafts is contraindicated for small caliber bypass (
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: K.A. Rocco, M.W. Maxfield, P.S. Bagi, H. Kurobe, T. Yi, T. Shinoka, C.K. Breuer Source Type: research

Intravenous Multipotent Adult Progenitor Cell Therapy Improves Spatial Learning After Traumatic Brain Injury
Traumatic brain injury (TBI) is a major cause of death and disability. TBI results in primary changes in cerebral blood flow and intracranial pressure with dire secondary changes that include inflammation and cell death. As a result, TBI can cause cognitive, physical and behavioral deficits that are dependent on the severity and location of the injury. We have demonstrated previously that the intravenous delivery of multipotent adult progenitor cells (MAPCs) after traumatic brain injury provides neuroprotection by preserving the blood brain barrier and systemically attenuating inflammation. But, the cognitive and behaviora...
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: S.S. Bedi, R.A. Hetz, A. Olsen, S. Williams, C. Thomas, P. Smith, J. Hamilton, R.W. Mays, C.S. Cox Source Type: research

Fresh Red Blood Cells Mitigate Human T-cell Suppression Seen with Stored Blood Bank Red Blood Cells
Transfusion of packed red blood cells, while often necessary and life-saving, can produce a myriad of immunologic derangements. This phenomenon, known as transfusion-related immunomodulation (TRIM), demonstrates both immunosuppressive and immunostimulatory effects. Prior studies have shown that exposure to packed red blood cells (PRBCs) will suppress the normal proliferative response of human T cells in culture. This is not a consequence of apoptosis or necrosis. PRBCs of varying ages have exhibited similar behavior. By replacing PRBCs with fresh red blood cells, proliferative capabilities of T cells are restored.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: K.L. Long, C.F. Meier, S.P. Carmichael, J.G. Woodward, A.C. Bernard Source Type: research

Synthesis and Characterization of a Targeted Nitric Oxide-Delivery Vehicle
Vascular interventions continue to fail from restenosis secondary to neointimal hyperplasia. To prevent neointimal hyperplasia, we are developing a novel targeted therapy capable of delivering a therapeutic agent to the site of vascular injury via systemic administration, using a highly customizable peptide amphiphile (PA). We have previously shown that our PA, targeted to a unique collagen-binding sequence (since collagen is exposed to the circulation only after endothelial denudation) localizes to the site of injury after systemic injection. The goal of this current project is to develop and characterize a nitric oxide (...
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: E.S. Moreira, T. Moyer, H. Kassam, S.I. Stupp, M.R. Kibbe Source Type: research

Early Postoperative Oral Feeding in Gastresophageal Tumors Surgery: A Randomized Controlled Trial
With advancements in postoperative cares, attentions are now attracted toward fast recovery after surgery for upper gastrointestinal tumors. For this reason, modern postoperative care (also called Fast Track) now suggests early initiation of oral feeding in patients undergoing resection of gastroesophageal malignancies. However, evidences regarding safety and efficacy of early oral feeding (EOF) after curative gastrectomy and/or esophagectomy are scarce. Moreover, there is not sufficient randomized clinical trial (RCT) regarding this issue. Hence, we conducted the present RCT to investigate clinical outcomes of EOF in pati...
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: S. Shoar, H. Mahmoodzadeh, N. Hosseini Araghi, N. Mahboobi, F. Sirati, Z. Khorgami Source Type: research

Does Pay-for-Performance Improve Surgical Outcomes? Evaluation of Phase 2 of the Premier Hospital Quality Incentive Demonstration Project
Medicare's flagship Pay-for-Performance program, the Premier Hospital Quality Incentive Demonstration (HQID), was initiated in 2003 to reward high performers. The program redesigned its incentive structure in 2006 to also reward quality improvers. The impact of the change in incentive structure on outcomes in surgical populations is unknown.
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: T. Shih, J.B. Dimick Source Type: research

Anticoagulation is Unnecessary for Most Patients With Calf Vein Thrombosis
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: M.J. Anstadt, J.A. Brosius, T. Robertson, R. Milner Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

Anti-Inflammatory Drug Methotrexate Suppresses Experimental Abdominal Aortic Aneurysm in Mice
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: B. Xu, H. Xuan, X. Hu, H. Tanaka, W. Wang, M.E. Gerritsen, R.L. Dalman Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

Novel NF-kB Inhibitor Rescues Mice With High IL-6 Levels in Sepsis, and Reduces Gut Apoptosis in Double Hit Injury: Sepsis Followed by Hemorrhage
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: D. VYAS, S. Samsophear, P. Castro, L. Chaturvedi, L. Azevedo, J. Tepe, M. Basson, S. Patel, A. Vyas Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

Xanthine Oxidoreductase Mediates Wound Healing in C57BL/6 Mice Through Hydrogen Peroxide
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: M.C. Madigan, B.S. Zuckerbraun, M.M. Tarpey, G. Hong, E. Tzeng Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

NADPH Oxidase 2 Deficiency Attenuates Experimental Abdominal Aortic Aneurysm in Mice
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: B. Xu, H. Xuan, H. Tanaka, X. Hu, W. Wang, K.J. Glover, R.L. Dalman Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

The Effect of Surgeon Specialty on Outcomes After Ruptured Abdominal Aortic Aneurysm Repair
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: A.T. Hawkins, A.D. Smith, M.J. Schaumeier, N.D. Hevelone, L.L. Nguyen Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

Mid-term Clinical Outcome of Critical Limb Ischemia After Infrapopliteal Bypass Surgery
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: R. Kyuragi, T. Matsumoto, S. Tanaka, J. Okadome, E. Kawakubo, R. Fukunaga, J. Okazaki, Y. Maehara Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

Differential PECAM-1 Activation and Tissue Factor Expression in HUVEC Exposed to Laminar and Disturbed Pulsatile Flow and Chemical Stimuli
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: T. Moriguchi, B. Davis, R. Abe, B.E. Sumpio Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

Significance of Macrophage-Association Markers in Human Carotid Plaques
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: S.L. Powell White, R.Q. Ding, E. Hitchner, W. Zhou Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

Novel Role of WISP-1/CCN4 in Angiogenesis
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: Z. Liu, Y. Tan, H. Shao, Y. Li, O.C. Velazquez Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

Increased Adipocyte Deposition in Injured Muscle With Aging and Impaired Remodeling in Females
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: C.M. Fearing, H.M. Hancock, M.J. McHale, L. Porter, Z.U. Sarwar, L.M. McManus, P.K. Shireman Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

Single Cell Transcriptional Analysis Reveals A Diminished Subpopulation of Human Adipose Derived Stem Cells in Diabetic Patients
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: M. Sorkin, R. Rennert, M. Januszyk, J.M. Morton, M.T. Longaker, G.C. Gurtner Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research

Femoral Intima Media Thickness as a Marker for Peripheral Arterial Disease
Source: Journal of Surgical Research - January 10, 2013 Category: Surgery Authors: M.S. Etherington, A.J. Layne, E.R. Mohler, J.T. Davis, R.M. Fairman, E.Y. Woo, B.M. Jackson, G.J. Wang Tags: Quickshot Session: Tuesday 2/5 7:30 AM to 9:30 AM Source Type: research