Toxicology 
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Acaricidal Activity of DHEMH, Derived from Patchouli Oil, against House Dust Mite, Dermatophagoides farinae.
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This study characterized the acaricidal activity of constituents of patchouli oil extracted from (Pogostemon cablin (Blanco) BENTH) against the house dust mite, Dermatophagoides farinae. A new compound, 2-(1,3-dihydroxy-but-2-enylidene)-6-methyl-3-oxo-heptanoic acid (DHEMH), was isolated from patchouli oil and characterized by (1)H-NMR, (13)C-NMR, LC-MS and elemental analysis (EA). This active component was identified as the hydrolysate of pogostone. Fifteen other constituents found in patchouli oil were also identified by GC-MS, including patchouli alcohol and pogostone. LD(50) studies carried out over 24 h using contac...
Source: Chemical and Pharmaceutical Bulletin - February 6, 2012 Category: Drugs & Pharmacology Authors: Wu HQ, Li L, Li J, He ZD, Liu ZG, Zeng QQ, Wang YS Tags: Chem Pharm Bull (Tokyo) Source Type: research
Clinical and Forensic Signs Related to Cocaine Abuse. - Dinis-Oliveira RJ, Carvalho F, Duarte JA, Proença JB, Santos A, Magalhães T.Email this article to a colleague.
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Good laboratory practice in toxicological analysis requires pre-analytical steps for collection of detailed information related to the suspected poisoning episodes, including biological and non-biological circumstantial evidences, which should be carefully... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - February 6, 2012 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
Scientists Prove Multiple DNA Repair Defect In MonocytesEmail this article to a colleague.
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Scientists working with Professor Bernd Kaina of the Institute of Toxicology at the Medical Center of Johannes Gutenberg University Mainz have demonstrated for the first time that certain cells circulating in human blood - so-called monocytes - are extremely sensitive to reactive oxygen species (ROS). They were also able to clarify the reason for this: ROS are aggressive forms of oxygen that are generated during states of "oxidative stress" and play a significant role in various diseases... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 6, 2012 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news
Can sugar really be toxic? Sadly, yesEmail this article to a colleague.
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Eating excessive amounts of processed sugar is leading to an epidemic in type 2 diabetes, finds Max Pemberton. (Source: Telegraph Health)
Source: Telegraph Health - February 6, 2012 Category: Consumer Health News Source Type: news
Imatinib and beyond - targeting activated tyrosine kinases in myeloproliferative disorders.Email this article to a colleague.
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Abstract
Tyrosine kinases (TKs) play a major role in cellular signal transduction. Deregulated TK activity has been observed in solid cancers and hematologic malignancies. Advances in the understanding of the oncogenic activation of TKs led to the identification of new kinase inhibitors with improved potency, specificity, and efficacy. With the advent of imatinib mesylate, a new era in the management of patients with BCR-ABL+ chronic myelogenous leukemia (CML), gastrointestinal stromal tumors, and myeloproliferative neoplasms including chronic myelomonocytic leukemia with PDGFRB gene rearrangements and hypereosinop...
Source: Onkologie - February 5, 2012 Category: Cancer & Oncology Authors: Hochhaus A, Reiter A, Ernst T, La Rosée P Tags: Onkologie Source Type: research
What Are the Major Diseases Involving Copper Metabolism?Email this article to a colleague.
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Discussion
Nutritional problems can occur in all parts of the world and in all socioeconomic strata. Caloric and/or protein inadequacy unfortunately plagues too many people because of inadequate supplies or availability. Supplemental food programs around the world attempt to provide appropriate nutrition, but can be stymied because of war, political instability, economic instability and many other social factors.
The most common specific nutrient deficiencies are iron and Vitamin D deficiencies. Minerals important for essential nutrition include copper, iodine, selenium and zinc. A typical mixed diet usually provides enou...
Source: PediatricEducation.org - February 5, 2012 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news
The “Black Widow”: Arsenic and Britain’s First Serial KillerEmail this article to a colleague.
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The Daily Mail (U.K.) has a fascinating story today about Mary Ann Cotton (1832 – 1873), Britain’s first serial killer. According to the author, Professor of Criminology David Wilson, a serial killer is someone who kills more than three people over a time period of more than thirty days. Cotton more than met this definition:
Few have heard of the so-called “Black Widow” killer who posed as a wife, widow, mother, friend and nurse to murder perhaps as many as 21 victims [over a period of almost 20 years], living off her husbands before eventually claiming their estates. Two decades before Jack the Rip...
Source: The Poison Review - February 5, 2012 Category: Toxicology Authors: Leon Tags: Medical arsenic black widow forensic toxicology mary ann cotton poisoner serial killer Source Type: news
Abbreviated Radiotherapy Shows Promise in Prostate CaEmail this article to a colleague.
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SAN FRANCISCO (MedPage Today) -- Dramatically condensing radiation treatment for early prostate cancer into just five fractions produces good results without much toxicity, an early-phase study suggested. (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 5, 2012 Category: Hematology Source Type: news
Effect of Arrabidaea chica extracts on the Ehrlich solid tumor developmentEmail this article to a colleague.
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In conclusion, the ethanol and aqueous extracts of A. chica have immunomodulatory and antitumor activities attributed to the presence of flavonoids, such as kaempferol. These effects appear to be related to different mechanisms of action for each extract. This study demonstrates the potential of A. chica as an antitumor agent confirming its use in traditional popular medicine. (Source: Revista Brasileira de Farmacognosia)
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Chemical constituents and evaluation of the toxic and antioxidant activities of Averrhoa carambola leavesEmail this article to a colleague.
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The liquid-liquid partitioning of a crude hydroalcoholic extract of Averrhoa carambola L., Oxalidaceae, leaves led to the isolation of a sterol and three flavone C-glycosides. From the n-hexane fraction β-sitosterol was isolated and from the ethyl acetate fraction apigenin-6-C-β-L-fucopyranoside (1) and apigenin6-C-(2"-O-α-L-rhamnopyranosyl)-β-L-fucopyranoside (2) were obtained. Apigenin6-C-(2"-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside (3) was isolated from the n-butanol fraction. Compound 3 is new, while 1 and 2 have been previously isolated from A. carambola. The antioxidant activity was measured using the DPPH ra...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Wogonin and neobaicalein from Scutellaria litwinowii roots are apoptotic for HeLa cellsEmail this article to a colleague.
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Chemical investigation on the CH2Cl2 fraction of the Scutellaria litwinowii Bornm. & Sint., Lamiaceace, root extract for the first time resulted in the isolation of wogonin, and neobaicalein. These compounds were evaluated for their cytotoxicity towards HeLa cell lines and lymphocytes. Meanwhile, the role of apoptosis was explored in this toxicity. The cells were cultured in RPMI medium and incubated with different concentrations of isolated flavonoids. Cell viability was quantified by MTS assay. Apoptotic cells were determined using propidium iodide staining of DNA fragmentation by flow cytometry (sub-G1peak). Wogonin, an...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Zuclopenthixol: Various toxicities: case reportEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Lamotrigine overdose: Cardiovascular collapse and other toxicities: case reportEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Fluconazole/posaconazole/tretinoin interaction: Gastrointestinal and hepatic toxicity: case reportEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Disulfiram/alcohol interaction: Various toxicities following overdoses, treated with fomepizole: 2 case reportsEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Dasatinib/nilotinib: Various toxicities: case reportEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Dactinomycin/melphalan: Various toxicities: 11 case reportsEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Cisplatin/pemetrexed: Toxic epidermal necrolysis: case reportEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Baclofen overdose: Various toxicities: case reportEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Azithromycin: Hepatocellular toxicity and hepatic encephalopathy in an elderly patient: case reportEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Antineoplastics/folinic acid: Diarrhoea and skin toxicity in an elderly patient: case reportEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Antineoplastics: Various toxicities in older patients: 13 case reportsEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Adalimumab/efalizumab/etanercept/infliximab: Various toxicities: 19 case reportsEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Autophagic proteins: New facets of the oxygen paradox.Email this article to a colleague.
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Abstract
Oxygen (O 2), while essential for aerobic life, can also cause metabolic toxicity through the excess generation of reactive oxygen species (ROS). Pathological changes in ROS production can originate through the partial reduction of O 2 during mitochondrial electron transport, as well as from enzymatic sources. This phenomenon, termed the oxygen paradox, has been implicated in aging and disease, and is especially evident in critical care medicine. Whereas high O 2 concentrations are utilized as a life-sustaining therapeutic for respiratory insufficiency, they in turn can cause acute lung injury. Alveolar ep...
Source: Autophagy - February 5, 2012 Category: Cytology Authors: Jin Y, Tanaka A, Choi AM, Ryter SW Tags: Autophagy Source Type: research
Carotenoid deficiency triggers autophagy in the model green alga Chlamydomonas reinhardtii.Email this article to a colleague.
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In this study we used the unicellular green alga Chlamydomonas reinhardtii to demonstrate that defects in carotenoid biosynthesis lead to the activation of autophagy, a membrane-trafficking process that participates in the recycling and degradation of damaged or toxic cellular components. Carotenoid depletion caused by either the mutation of phytoene synthase or the inhibition of phytoene desaturase by the herbicide norflurazon, resulted in a strong induction of autophagy. We found that high light transiently activates autophagy in wild-type Chlamydomonas cells as part of an adaptation response to this stress. Our results ...
Source: Autophagy - February 5, 2012 Category: Cytology Authors: Pérez-Pérez ME, Couso I, Crespo JL Tags: Autophagy Source Type: research
All bath salts are not mephedroneEmail this article to a colleague.
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2.5 out of 5 stars
“Bath Salt” Ingestion Leading to Severe Intoxication Delirium: Two Cases and a Brief Review of the Emergence of Mephedrone Use. Kasick DP et al. Am J Drug Alcohol Abuse 2012 Jan 5 [Epub ahead of print]
Abstract
This paper from the Ohio State Department of Psychiatry is worth reading for vivid descriptions of acute toxic delirium in two patients after they used a product sold as “bath salts”:
Patient A presented after ingesting “bath salts” sold under the label “Arctic Blast”. He was tachycardic (heart rate = 144.min), anxious and paranoid, and suffering ...
Source: The Poison Review - February 4, 2012 Category: Toxicology Authors: Leon Tags: Medical bath salts mephedrone synthetic cathinones Source Type: news
Molecular dynamics to combat chemical terrorismEmail this article to a colleague.
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A computer programme to find a pathway to decontaminate VX, a toxic nerve agent that featured in the Nicolas Cage film The Rock (Source: Chemistry World | Latest News)
Source: Chemistry World | Latest News - February 3, 2012 Category: Chemistry Source Type: research
Toxic mushroom behind Chinese deaths unmaskedEmail this article to a colleague.
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The killer chemicals that have claimed hundreds of lives in China have been identified in a new species of fungi (Source: Chemistry World | Latest News)
Source: Chemistry World | Latest News - February 3, 2012 Category: Chemistry Source Type: research
[Perspective] Evolution: Surviving in a Toxic WorldEmail this article to a colleague.
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Natural variations in a single gene of wild C. elegans populations confer resistance to the bacterial toxin avermectin.Author: Adrian J. Wolstenholme (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Adrian J. Wolstenholme Source Type: research
Febuary eFactorEmail this article to a colleague.
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Weis addresses industrial hygiene group on mineral fibers
LST fellow makes a move from lab bench to global health
Former NIEHS staff fellow named vice chancellor
Staffers and trainees gain toxicology certification
NIH turns 125
Public health officials work to keep research first during a tough economy
Prins honored by University of Illinois at Chicago
NIEHS Public Interest Partner honored
Superfund promotes safe drinking water at Agua Fria Festival
Registration is underway for NIEHS and HHS national research conference
NTP toxicologist Kamal Abdo remembered
Minisymposium brings epigenetic experts to NIEHS
BPA r...
Source: Environmental Factor - NIEHS Newsletter - February 3, 2012 Category: Environmental Health Source Type: news
What Are the Therapeutic Effects of High-Dose Intravenous Prednisolone in Methanol-Induced Toxic Optic Neuropathy?Email this article to a colleague.
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Journal of Ocular Pharmacology and Therapeutics , Vol. 0, No. 0. (Source: Journal of Ocular Pharmacology and Therapeutics)
Source: Journal of Ocular Pharmacology and Therapeutics - February 3, 2012 Category: Opthalmology Tags: article Source Type: research
Genotoxicity, cytotoxicity and toxicological evaluation of whole plant extracts of the medicinal plant Phyllanthus niruri (Phyllanthaceae).Email this article to a colleague.
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We examined the geno-, cyto- and overall toxicity of P. niruri whole plant ethanolic extract. The extract was administered as a single dose of 30 or 300 mg/kg to laboratory rats by gavage, accompanied by negative (0.9% saline) and positive (10 mg/mL N-ethyl-N-nitrosourea) controls that were injected intramuscularly 48 h after extract administration. The ratio of polychromatic (PCE)/normochromatic erythrocytes (NCE) from femur bone marrow was scored for genotoxicity. Cytotoxicity was determined using descending concentrations (0.2-0.0125 g/mL) of the extract incubated with peripheral blood mononuclear cells. Lactate dehydro...
Source: Genetics and Molecular Research - February 3, 2012 Category: Genetics & Stem Cells Authors: Asare GA, Bugyei K, Sittie A, Yahaya ES, Gyan B, Adjei S, Addo P, Wiredu EK, Adjei DN, Nyarko AK Tags: Genet Mol Res Source Type: research
Switching between anti-TNF-alpha agents does not improve functional capacity in patients with long-standing and active rheumatoid arthritisEmail this article to a colleague.
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CONCLUSION: Switching between anti-TNF-alpha agents is a valid strategy to control disease activity, despite the low likelihood of remission and no significant improvement in functional capacity (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Sugar Should Be Regulated Like Alcohol And Tobacco Say ScientistsEmail this article to a colleague.
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Scientists at the University of California, San Francisco (UCSF), argue that added sweeteners pose dangers to public health, and the government should regulate sugar in the same way as it regulates alcohol and tobacco. They set out their reasons for viewing sugar as "toxic" in a comment article published in Nature this week. First author Robert H... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 3, 2012 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news
Prediction of environmental concentrations of glucocorticoids: The River Thames, UK, as an example.Email this article to a colleague.
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Abstract
Synthetic glucocorticoids (GCs) are consumed in large amounts as anti-inflammatory and immunosuppressive drugs worldwide. Based on what has been learnt from studies of other human pharmaceuticals, they are likely to be present in the aquatic environment. However, to date, information on the environmental concentrations of GCs is very limited. The situation is complicated by the fact that a considerable number of GCs are in everyday use in most developed countries. Hence, obtaining a full picture of GC concentrations in the aquatic environment using the traditional analytical chemistry approach would be tim...
Source: Environment International - February 3, 2012 Category: Environmental Health Authors: Kugathas S, Williams RJ, Sumpter JP Tags: Environ Int Source Type: research
Cadmium [video] | GrrlScientistEmail this article to a colleague.
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What do nuclear reactors, marine diatoms and Monet have in common?This week's element is cadmium, represented by the atomic symbol, Cd, and the atomic number, 48. It is a ductile silvery metal that is special because it is corrosion resistant. Cadmium once had a variety of uses but because it is highly toxic and readily accumulates in living things, its use is being phased out, although it still is in demand by the electronics industry. Named for cadmia (also known as calamine), a naturally occurring form of zinc carbonate, cadmium was originally discovered independently and simultaneously by several Germans after heating...
Source: Guardian Unlimited Science - February 3, 2012 Category: Science Authors: GrrlScientist Tags: Periodic Table Chemistry Science guardian.co.uk Blogposts Source Type: news
Detection Of Cyanide Poisoning Extended By Forensic ResearchEmail this article to a colleague.
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Researchers have found a new biomarker for cyanide poisoning, which may extend its detection window in death investigations by weeks if not months. Unless cyanide is discovered at the time of death on the mouth or nose, elevated cyanide concentrations can only be found for up to two days under current toxicological testing. A team of researchers have found a substance that appears in the liver following cyanide poisoning that could serve as a stable biomarker for a longer period of time. The research, by Dr... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 3, 2012 Category: Consumer Health News Tags: Public Health Source Type: news
Source Of Damage To Donor Organs IdentifiedEmail this article to a colleague.
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For patients with incurable pulmonary conditions, a lung transplantation is the only available treatment option. However, suitable donor organs are scarce, and even getting them to prospective recipients is not easy. As Professor Alexander Dietrich of the Walther Straub Institute of Pharmacology and Toxicology at LMU explains, "An isolated lung which is no longer perfused with blood can become so severely damaged that it is no longer functional. This so-called ischemia-reperfusion injury is one of the major problems in the field of lung transplantation... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 3, 2012 Category: Consumer Health News Tags: Transplants / Organ Donations Source Type: news
Alzheimer's-Related Protein In Brains Of Healthy Adults May Shed Light On Earliest Signs Of DiseaseEmail this article to a colleague.
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Researchers from the Center for Vital Longevity at the University of Texas at Dallas and UT Southwestern Medical Center have completed a large-scale neuroimaging study of healthy adults from age 30 to 90 that measured beta-amyloid protein - a substance whose toxic buildup in the brain is a diagnostic marker for Alzheimer's disease. The findings, published in the online issue of Neurology, the medical journal of the American Academy of Neurology, mark a crucial step toward being able to predict who may be at risk for developing Alzheimer's disease long before symptoms appear... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 3, 2012 Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news
Series of 8 cases of Irukandji syndrome? or bait-and-switchEmail this article to a colleague.
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1.5 out of 5 stars
Irukandji Sydrome [sic] in the Torres Strait: A Series of 8 Cases. McIver LJ et al. Wilderness Environ Med 2011;22:338-342.
Abstract
The problems with this paper merely begin with the dropped “n” in the second word of the title. Then we get to the first sentence of the abstract, where despite the title’s promise of a case series of Irukandji syndrome (or sydrome, or whatever) we find a classic medical literature bait-and-switch:
Objective–To review the presentations of a series of patients with suspected Irukandji syndrome in the Torres Strait, where the syndrome has hitherto bee...
Source: The Poison Review - February 3, 2012 Category: Toxicology Authors: Leon Tags: Medical carukia barnesi irukandji syndrome jellyfish sting Source Type: news
Modification of TiO(2) nanotube surfaces by electro-spray deposition of amoxicillin combined with PLGA for bactericidal effects at surgical implantation sites.Email this article to a colleague.
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Conclusions. This study used electro-spray deposition (ESD) methodology to obtain amoxicillin deposition in nanotube structures of TiO(2) and found the optimal deposition time of amoxicillin/PLGA solution simultaneously performing non-toxicity and a high bactericidal effect for preventing early implant failures.
PMID: 22299831 [PubMed - as supplied by publisher] (Source: Acta Odontologica Scandinavica)
Source: Acta Odontologica Scandinavica - February 3, 2012 Category: Dentistry Authors: Lee JH, Moon SK, Kim KM, Kim KN Tags: Acta Odontol Scand Source Type: research
Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injuryEmail this article to a colleague.
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Conclusions
These results demonstrate the successful pharmacological inhibition of hepatic monocyte/macrophage infiltration by blocking MCP-1 during chronic liver damage in two in vivo models. The associated ameliorated steatosis development suggests that inhibition of MCP-1 is an interesting novel approach for pharmacological treatment in liver inflammation and steatohepatitis. (Source: Gut)
Source: Gut - February 3, 2012 Category: Gastroenterology Authors: Baeck, C., Wehr, A., Karlmark, K. R., Heymann, F., Vucur, M., Gassler, N., Huss, S., Klussmann, S., Eulberg, D., Luedde, T., Trautwein, C., Tacke, F. Tags: Nonalcoholic steatosis Hepatology Source Type: research
In vitro and in vivo safety evaluation of Dipteryx alata Vogel extractEmail this article to a colleague.
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Conclusion:
D. alata barks extract is neither mutagenic by the Ames test nor toxic in the pregnancy of rats, with no physical-neurobehavioral consequences on the rat offsprings development. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - February 3, 2012 Category: Complementary Medicine Authors: Natalia Esteves-PedroThaisa BorimVirginia SbrunegaMagali SilvaPatricia SantosMarcio SantosChariston Dal BeloCassia Regina CardosoEliana VarandaFrancisco GropoMarli GerenuttiYoko Oshima-Franco Source Type: research
Removing Hexazinone from Groundwater with Microbial Bioreactors.Email this article to a colleague.
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Abstract
Hexazinone, a triazine herbicide that is often detected as a ground and surface water contaminant, inhibits electron transport in photosynthetic organisms and is toxic to primary producers that serve as the base of the food chain. This laboratory study evaluated the ability of two types of microbial reactors, i.e., a vegetable oil-based nitrogen-limiting biobarrier and an aerobic slow sand filter, as methods for removing hexazinone from simulated groundwater. The N-limiting biobarriers degraded hexazinone, but did so with a 52 week incubation period and a removal efficiency that varied greatly among repli...
Source: Current Microbiology - February 3, 2012 Category: Microbiology Authors: Hunter WJ, Shaner DL Tags: Curr Microbiol Source Type: research
Countering health threats by chemicals with a potential terrorist background - creating a rapid alert system for Europe.Email this article to a colleague.
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CONCLUSION: The RAS-CHEM database works and will be integrated into the Health Emergency Operations Facility (HEOF) with other European Rapid Alert Systems. Poisons centres receive a large number of enquiries and could be important sentinels in this field of toxicovigilance.
PMID: 22284259 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - February 2, 2012 Category: Internal Medicine Authors: Schaper A, Desel H, Wyke S, Orford R, Griffiths MR, Edwards N, Kupferschmidt H, Mathieu M, Pelclova D, Duarte-Davidson R Tags: Eur J Intern Med Source Type: research
Surface Plasmon Resonance Optical Sensor for Detection of Essential Heavy Metal Ions with Potential for Toxicity: Copper, Zinc and Manganese IonsEmail this article to a colleague.
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(Source: Sensor Letters)
Source: Sensor Letters - February 2, 2012 Category: Medical Equipment Authors: Fen, Yap WingYunus, W. Mahmood MatYusof, Nor Azah Tags: Research Articles Source Type: research
Most Common Tx for Prostate Ca Not Best ValueEmail this article to a colleague.
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SAN FRANCISCO (MedPage Today) -- External beam radiation is the most toxic and expensive among common prostate cancer treatments over the long-term, a national registry study suggested. (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 2, 2012 Category: Hematology Source Type: news
Untangling the mysteries of Alzheimer'sEmail this article to a colleague.
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Researchers have found new evidence that confirms the significance of a protein that neuroscientists call tau to the development of Alzheimer's disease. While earlier studies have focused on tau's aggregation into twisted structures known as "neurofibrillary tangles," the new work emphasizes intermediary steps between single protein units and the much larger tangles – small assemblages of two, three, four or more proteins, which the investigators believe are the most toxic entities in Alzheimer's. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 2, 2012 Category: Science Source Type: news
Various drugs: Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme and maculopapular eruptions: 30 case reportsEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 2, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Vaccines: Various toxicities: 9 case reportsEmail this article to a colleague.
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(Source: Reactions)
Source: Reactions - February 2, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
