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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 23.

New autism risks for school-aged children: Playing at recess and eating fruits and veggies during snack time
According to the work produced by the Greater Boston Physicians for Social Responsibility in 2000, In Harm's Way: Toxic Threats To Child Development, millions of U.S. children exhibit learning disabilities, reduced IQ, and destructive, aggressive behavior due to toxic...
Source: NaturalNews.com - September 22, 2012 Category: Consumer Health Advice Source Type: news

This column will change your life: complainers
Is it time to stop moaning about moaners?Sorry to moan, but have you seen the bad press complainers have been getting lately? Sometimes – hey, don't back away, I want you to listen! – it seems as if you can't open a lifestyle magazine, or self-help book, without being lectured on the importance of avoiding whiners. According to one typical piece, from the American business magazine Inc, spending 30 minutes with a complainer literally destroys your brain, "peel[ing] away neurons in the brain's hippocampus". Yes, you read that correctly. Just half an hour listening to a colleague complaining – about the broken off...
Source: Guardian Unlimited Science - September 21, 2012 Category: Science Authors: Oliver Burkeman Tags: The Guardian Psychology Health & wellbeing Features Life and style Source Type: news

Overactive Bladder Models
The overactive bladder (OAB) can be defined in humans as a urodynamic observation (detrusor overactivity), or symptomatically (urgency, frequency, incontinence, nocturia) as the OAB syndrome. For obvious reasons, there are no animal models of the OAB syndrome. In humans, urinary incontinence can be due to involuntary bladder contractions demonstrable by cystometry during the filling phase. In animals, cystometric bladder hyperactivity (bladder contractions voluntary and/or involuntary) can be found in many animal models. It can occur spontaneously or be provoked, and the pathophysiology may include both peripheral and cent...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

Animal Models of Cystitis
As in other areas of biomedical research, studies of bladder pathology rely heavily in animal models of cystitis. These can be basically divided in two types: induced by systemically administration and locally induced by challenge with immunogens or irritants. The choice between models is not easy, and several factors must be taken into account, namely side effects, intensity of the pathology, simplicity, and/or reproducibility of the method.
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

TRP Channels in the Genitourinary Tract
Recently, TRP channels have been implicated in numerous pathologies of the genitourinary (GU) tract. TRP channels are differently expressed along the GU tract, and several lines of evidence suggest that they also have different roles in the pathophysiology of GU tract diseases. In this chapter, we focus on the expression and role of TRP in the urinary bladder and give an overall idea of TRP channel expression and function in the remaining GU tract.
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

Capsaicin Inhalation Test in Man
Stimulation of TRP receptors on sensory nerves is likely involved in chemically induced airway symptoms. A subgroup of patients has been identified with nonallergic, nonasthmatic symptoms from the upper and lower airway that are induced by environmental stimuli normally regarded as nontoxic. These patients have substantially increased cough response to inhaled capsaicin, known to initiate cough via TRPV1 receptors on airway sensory nerves. Hence, the condition has been termed sensory hyperreactivity (SHR). As a diagnostic tool of SHR, a standardized capsaicin inhalation cough test was developed. However, the capsaicin inha...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

Enhanced Cough, Animal Models
Under specific pathophysiological circumstances, cough becomes a chronic condition. Unfortunately, apart from drugs that treat the underlying diseases that cause the cough symptom, medicines directly oriented to reduce or abolish the cough reflex are limited to narcotic or narcotic-like drugs. The poor availability of antitussive medications is due to many causes but mainly to the poor understanding of the molecular mechanisms that cause and maintain chronic cough. Most of the mechanistic information on cough has been generated from animal models in which there is little or no airway pathology. It is essential then to deve...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

Endotoxin-Induced Airway Inflammation and Asthma Models
Lung inflammation models in experimental animals are particularly important to study the mechanisms and complex neuroimmune interactions involved in the pathophysiological processes, to identify key mediators and target molecules, as well as to test novel drug candidates. Endotoxin (lipopolysaccharide) administration locally into the airways (intranasally or intratracheally) is often used in a variety of laboratory animals for translational research to explore nonallergic inflammatory pathways, as well as to provide information on important mediators and their potential drug targets, although these conditions are not consi...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells
Hypoxic pulmonary vasoconstriction (HPV) is an essential physiological mechanism of the lung which matches perfusion to ventilation to optimize gas exchange. Pulmonary arterial smooth muscle cells (PASMC) are the effector and possibly also the sensor cells of HPV. Contraction of these cells under hypoxia is induced by an increase in intracellular Ca2+ concentration ([Ca2+]i). To investigate details of the hypoxia-induced increase in [Ca2+]i, we use a live cell imaging procedure with fura-2 in isolated wild-type (WT) and gene-deficient mouse PASMC. We also describe here the manganese-quenching method to determine the role o...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

TRP Expression and Function in the Lung Airways
The airways of the lungs are composed of the epithelium, smooth muscle cells, and sensory nerve cells as well as resident immune cells. Transient receptor potential (TRP) channels are expressed in all of these tissues and cells and there is increasing evidence that they play a key role in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). This chapter focuses on what is currently known about TRP expression and function in lung airways by studying specific channel blockers as well as TRP-deficient mouse models. Targeting selected TRP functions may have important therapeutic benefits for re...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

TRPML Channels in Function, Disease, and Prospective Therapies
The transient receptor potential mucolipin (TRPML) subfamily of transient receptor potential cation channels consists of three members (TRPML1-3) that function at various stages of endocytosis. Conventional research in the TRPML field suggests that dysfunction along these endocytic stages underlies the severe psychomotor impairment in mucolipidosis type IV (MLIV). However, recent studies intimate that TRPMLs may be implicated in other neuropathological disorders as well. This review follows the historical development of TRPML research from the clinical description of the first MLIV patient until present-day characteri...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

TRPM8 Channels as Potential Therapeutic Targets for Pain, Analgesia, and Thermoregulation
The perception of temperature is critical in not only acute responses to changes in the environment but also fundamental in regulating homeostatic mechanisms like core body temperature. The somatosensory system detects changes in ambient temperature via the coordinated efforts of thermosensory nerves expressing temperature-sensitive members of the TRP family of ion channels. These channels respond over a wide range of temperatures that covers the entire perceived spectrum from comfortably warm to painfully hot and from pleasingly cool to excruciatingly cold. Many of these channels are receptors for natural products that el...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

The Emerging Role of TRPM7 in the Regulation of Magnesium Homeostasis
We present evidence that TRPM7 is involved in the regulation of Mg2+ influx into proliferating cells, while the TRPM7–TRPM6 complex is involved in the regulation of whole body Mg2+ balance.
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

The Ca2+-Activated Monovalent Cation-Selective Channels TRPM4 and TRPM5
In this review we summarize the current data on the ion channels TRPM4 and TRPM5. These proteins are to date the only molecular candidates for the class of Ca2+-activated cation channels (CAN channels). They form monovalent cation-selective and Ca-impermeable ion channels, which are activated by a rise of the cytosolic Ca2+ concentration. They have been described in a plethora of tissues, and their physiological importance is only now being explored since knockout mice have become available.
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

TRPM2 Function and Potential as a Drug Target
The TRPM subfamily of transient receptor potential channels includes a number of members which are involved in cell proliferation or cell survival. TRPM2, the second member to be cloned, has a key role in the response to oxidative stress. After exposure to oxidant stress, TNFα, concanavalin A, or amyloid β-peptide, ADP-ribose is produced, which binds to a NUDT9-H domain in the C terminus and is a key regulator of channel opening and calcium influx. The important roles of TRPM2 isoforms in cell proliferation and oxidant-induced cell death have been well established in divergent cell types using a broad range of t...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

Canonical Transient Receptor Potential Channel Expression, Regulation, and Function in Vascular and Airway Diseases
The physiological function of all cells is uniquely regulated by changes in cytosolic Ca2+ levels. Although several mechanisms increase cytosolic Ca2+ levels, Ca2+ influx across the plasma membrane upon the release of Ca2+ from the internal stores is one of the major mechanisms in most nonexcitable cells and in some excitable cells. Such Ca2+ channels, which are activated by intracellular Ca2+ store depletion are referred to as store-operated Ca2+ entry (SOCE) channels and have been shown to be essential for many biological functions including fluid and enzyme secretion, immune regulation, hypertension, pulmonary function,...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

TRPA1 in Drug Discovery
TRPA1 is one of the few ion channels with human genetic validation for pain. A TRPA1 gain-of-function mutation is linked to familial episodic pain syndrome in humans. This milestone discovery, coupled with a growing preclinical literature implicating TRPA1 in multiple indications, has made TRPA1 an attractive therapeutic target. With extensive investment across the pharmaceutical industry, several novel nonreactive TRPA1 antagonist series have emerged in patents, and two TRPA1 compounds have recently advanced to human clinical trials. A review of the diverse roles for TRPA1 in pain signaling and other indications such as i...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

TRPV4 and Drug Discovery
Transient receptor potential vanilloid 4 (TRPV4) was first identified in 2000 as an osmolarity sensor. Further investigations rapidly revealed this ion channel to be a polymodal receptor with additional activating or modulating stimuli including warm temperatures, endogenous lipids, and phosphorylation. The broad tissue and cell type distribution of TRPV4, coupled with its varied activation profile, lead to a wide variety of physiological roles. These include sheer stress detection in blood vessels, osteoclast differentiation control in bone, along with temperature monitoring in skin keratinocytes and osmolarity sensing in...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

Nociceptive and Nonnociceptive Roles of TRPV3 and Its “Druggability”
Following the discovery of transient receptor potential vanilloid 1 (TRPV1), the founding member of the subfamily, knowledge accumulation on its biological roles in human pathology is being accelerated by its genetic, physiological, and pharmacological approaches. Owing to these scientific efforts, a series of its TRPV cousins have been found, and currently their characterizations are getting gradually active. TRPV3 was discovered as the last member a decade ago. To date, studies concerning TRPV3 revealed the distinct expression profiles in keratinocytes, extended modality to thermal and chemical insults, unique mode of se...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

TRPV1 as a Polymodal Sensor: Potential to Discover TRPV1 Antagonists Selective for Specific Activating Modalities
The transient receptor potential V1, or TRPV1, channel has a complex polymodal activation profile that integrates information from membrane potential changes, heat, and protons in addition to channel gating following ligand binding. TRPV1 is expressed along the peripheral pain pathway from the distal endings of nociceptor neurons to dorsal root ganglia; but has limited expression in the central nervous system and is detected in arteriolar smooth muscle cells and various epithelia. Several TRPV1 antagonist candidate drugs have been tested in clinical trials over the past 5 years with varying results. The reported side-effec...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

The TRPP Signaling Module: TRPP2/Polycystin-1 and TRPP2/PKD1L1
TRPP ion channels assemble with polycystin-1 family proteins into receptor-channel complexes. TRPP2–Polycystin-1 is required to coordinate renal three-dimensional tissue organization, whereas TRPP2–PKD1L1 is essential for establishment of left–right asymmetry during early embryonic development. The availability of orthologous and heterologous animal models made it feasible not only to characterize the function of single genes, but also to combine gene deficiencies and/or gene overexpression to establish molecular interdependencies. Canonical and noncanonical Wnt signaling have been associated with polycys...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

TRP-Mediated Cytoskeletal Reorganization: Implications for Disease and Drug Development
So far the major focus of Transient Receptor Potential (TRP) channels in the context of pathophysiological disorders was centered exclusively on the ionic conductivity mediated by these channels. However, recently the importance of non-ionic functions of TRP channels in different pathophysiological disorders has emerged. Recently several physical and functional interactions of TRP channels with cytoskeletal components have been characterized. These interactions play important roles in executing the non-ionic functions and regulations of TRP channels per se. In the membranous environment, TRP channels form dynamic signaling...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

Introduction to TRPs: A Quest for Novel Drug Targets
This introduction lists TRP channels as possible pharmaceutical targets and will also refer to some methodological and still scientific caveats. First, it will be highlighted which scientific problems are still necessary to solve, including permeation, gating regulation. This part leads to the methodological aspect of the book. Second, the well-known problem of evaluating expression of several TRP channels in organs which need to be affected will be shortly discussed. Third, natural compounds as evolutionary important small molecules to modify TRP functions will be added. Last, some important diseases which might have prio...
Source: Springer protocols feed by Pharmacology/Toxicology - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

2C-I: designer hallucinogen linked to North Dakota deaths
2C-I 3 out of 5 stars Morbidity Involving the Hallucinogenic Designer Amines MDA and 2C-I. Drees JC et al. J Forensic Sci 2009 Nov;54:1485-1487. Abstract 2C “designer” phenethylamines have high affinity for serotonin (5-HT2) receptors, and have hallucinogenic and stimulant properties somewhat similar to those of MDMA (ecstasy). This family of drugs gets its name because 2 carbon atoms separate the amine group from the ring structure. In the past TPR has discussed 2C-B, which has a bromine group substituted at the 4 position on the phenyl ring. The similar drug 2C-I has iodine in that position. Although this a...
Source: The Poison Review - September 21, 2012 Category: Toxicology Authors: Leon Tags: Medical 2C-B 2C-I death designer drug elijah stai fatality hallucinogen smiles Source Type: news

Nanostripes detect toxic metal cations
Simple sensor could test for toxins in drinking water and fish.
Source: Nanotechweb.org News - September 21, 2012 Category: Nanotechnology Source Type: news

Sperm Chromatin Structure Assay (SCSA®)
The SCSA® is the pioneering assay for the detection of damaged sperm DNA and altered proteins in sperm nuclei via flow cytometry of acridine orange (AO) stained sperm. The SCSA® is considered to be the most precise and repeatable test providing very unique, dual parameter data (red vs. green fluorescence) on a 1,024 × 1,024 channel scale, not only on DNA fragmentation but also on abnormal sperm characterized by lack of normal exchange of histones to protamines. Raw semen/sperm aliquots or purified sperm can be flash frozen, placed in a box with dry ice and shipped by overnight courier to an experienced SCSA&r...
Source: Springer protocols feed by Cell Biology - September 21, 2012 Category: Cytology Source Type: news

Transgenic Modification of Spermatogonial Stem Cells Using Lentiviral Vectors
The continuous production of spermatazoa throughout the reproductive lifetime of a male depends on the maintenance of a pool of progenitor cells called spermatogonial stem cells (SSCs). SSCs represent a very small fraction of the cellular population in the testes and lack definitive molecular markers for their identification. The discovery of conditions that allow one to propagate mouse SSCs in vitro essentially indefinitely has truly facilitated studies of the molecular mechanisms regulating SSC function. While multiple conditions for culturing SSCs have now been described, here we detail a method for culturing SSCs that ...
Source: Springer protocols feed by Cell Biology - September 21, 2012 Category: Cytology Source Type: news

TRP Channels in Drug Discovery
Volume Iseries:Methods in Pharmacology and ToxicologyRecent findings have implied a distinct therapeutic potential for drugs targeting Transient Receptor Potential (TRP) channels in a wide variety of diseases, many with no existing satisfactory treatment options. Thus, the TRP superfamily of ion channels has attracted a great deal of well-deserved attention. TRP Channels in Drug Discovery provides a thorough collection of the most up-to-date ...
Source: Springer Biomedical Sciences titles - September 21, 2012 Category: Biomedical Science Tags: Pharmacology / Toxicology Source Type: news

Fluoride toxicity - Protect yourself with selenium
Excess fluoride may increase your risk for 23 different cancers, lower your child's IQ and school performance and increase oxidative stress throughout your body. But new research has shown that the mineral selenium plays a key role in detoxifying excess fluoride, restoring...
Source: NaturalNews.com - September 21, 2012 Category: Consumer Health Advice Source Type: news

What non-alcohol drugs are used by drinking drivers in Sweden? Toxicological results from ten years of forensic blood samples - Jones AW, Holmgren A.
INTRODUCTION AND METHOD: Using a forensic toxicology database (TOXBASE), the toxicological results from 10years of forensic blood samples from people arrested for driving under the influence of alcohol and/or other drugs were reviewed. RESULTS: Alcohol was...
Source: SafetyLit: All (Unduplicated) - September 21, 2012 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Risk for ingestion of toxic substances in children with Prader-Willi syndrome - McCandless SE, Powell KP, Sandberg U.
This study examined whether individuals with PWS have an increased prevalence of toxic ingestions. A survey regarding...
Source: SafetyLit: All (Unduplicated) - September 21, 2012 Category: Global & Universal Tags: Age: Infants and Children Source Type: news

JOINT PAIN (Arnica Montana, Bryonia, Causticum, Rhus Toxicodendron, Ferrum Phosphoricum) Liquid [Deseret Biologicals, Inc.]
Updated Date: Sep 21, 2012 EST
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - September 21, 2012 Category: Drugs & Pharmacology Source Type: news

Cocaine-associated hyponatremia: is levamisole the culprit?
3 out of 5 stars Hyponatremia Associated with Levamisole-Adulterated Cocaine Use in Emergency Department Patients. Friend K et al. Ann Emerg Med 2012 Jul;60:94-96. Abstract According to reports from the U.S. Drug Enforcement Administration, 69% of illegal cocaine shipments seized in the United States are contaminated with the immunomodulator and anthelmintic agent levamisole. Exposure to this drug from cocaine abuse has been associated with agranulocytosis and necrotizing vasculitis. This case series, from the University of Pennsylvania School of Medicine, describes 3 patients who presented with hyponatremia (initial sod...
Source: The Poison Review - September 20, 2012 Category: Toxicology Authors: Leon Tags: Medical adulteration cocaine hyponatremia levamisole sodium Source Type: news

Stamp-Sized Device Could Cut Liver Test Costs (CME/CE)
(MedPage Today) -- A paper-based device about the size of a postage stamp could improve testing for drug-induced liver toxicity in the developing world, researchers reported.
Source: MedPage Today State Required CME - September 20, 2012 Category: Consumer Health News Source Type: news

Human environments: definition, scope, and the role of toxicology - Hodgson E.
This chapter is a brief introduction to the subject matter of the volume including the complexity and definition of human environments. Exposure to complex mixtures and the problem of interactions are considered as well as the important role of toxicology ...
Source: SafetyLit: All (Unduplicated) - September 20, 2012 Category: Global & Universal Tags: Poisoning Source Type: news

Chemicals of military deployments: revisiting gulf war syndrome in light of new information - Brimfield AA.
Despite the amount of hard work that has gone into elucidating a toxicological basis for Gulf War Illness, we do not appear to have reached a mechanistic understanding. Investigation of long-term low-level exposure as a basis does not seem to have provided...
Source: SafetyLit: All (Unduplicated) - September 20, 2012 Category: Global & Universal Tags: Occupational Issues Source Type: news

Fatal diving accidents in Western Norway 1983-2007 - Ramnefjell MP, Morild I, Mørk SJ, Lilleng PK.
Despite efforts to reduce their number, fatal diving accidents still occur. The circumstances and post-mortem findings in 40 fatal diving accidents in western Norway from 1983 through 2007 were investigated. Diving experience, medical history and toxicolog...
Source: SafetyLit: All (Unduplicated) - September 20, 2012 Category: Global & Universal Tags: Drowning, Suffocation Source Type: news

Claims of GM foods 'link to cancer' disputed by other researchers
Conclusion This study is reported to involve the highest number of rats regularly studied in a GM-diet study. The research also benefits from testing three different dietary concentrations of GM maize over a two-year period, along with GM maize treated with and without Roundup and Roundup alone diluted in water. All the rats in these groups were compared with rats fed only untreated, non-GM feed. The researchers also said that the Roundup concentration in water started at a dose below the range of levels permitted by regulatory authorities. Animal research such as this is highly valuable for looking at the possible toxic e...
Source: NHS News Feed - September 20, 2012 Category: Consumer Health News Tags: Food/diet Cancer Source Type: news

Biochemistry Of Inflammation Detected By Nanoparticles
Inflammation is the hallmark of many human diseases, from infection to neurodegeneration. The chemical balance within a tissue is disturbed, resulting in the accumulation of reactive oxygen species (ROS) such as hydrogen peroxide, which can cause oxidative stress and associated toxic effects. Although some ROS are important in cell signaling and the body's defense mechanisms, these chemicals also contribute to and are indicators of many diseases, including cardiovascular dysfunction...
Source: Health News from Medical News Today - September 20, 2012 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

Portland, Oregon votes to poison its citizens with toxic fluoride chemicals
We here at Natural News have reported regularly on the dangers of adding fluoride to our drinking water, always citing the latest research on the issue to make our point that, quite simply, ingesting even small amounts of the chemical over time can cause medical problems...
Source: NaturalNews.com - September 20, 2012 Category: Consumer Health Advice Source Type: news

Potentially inappropriate medication use in the elderly in Montenegro
Source: BMC Pharmacology and Toxicology Area: Evidence > Medicines Management > References Abstract of paper presented at the 18th Scientific Symposium of the Austrian Pharmacological Society (APHAR), joint meeting with the Croatian, Serbian and Slovenian Pharmacological Societies, Graz, Austria, 20-21 Sep 2012. Background: Potentially inappropriate medications (PIMs) continue to be prescribed and used as first-line treatment for the most vulnerable of older adults, despite evidence of poor outcomes from the use of PIMs in older adults. PIM use is an important and preventable safety concern in the car...
Source: NeLM - Care of Older People - September 20, 2012 Category: Geriatrics Source Type: news

'Zoobiquity' event looks at human and animal similarities in bullying, cancer, obesity, more
WHAT: Bullying among Welsh corgis, cats and children. Infertility in a panda, a cheetah and a math teacher. Self-injury by stallions and adolescents. When it comes to health and psychology, we really have more in common with animals than we think. The second annual "Zoobiquity" conference goes beyond the skin, fur and feathers to demonstrate how humans and animals are profoundly alike, with similar genetics and a striking overlap in health and disease. Over the course of a day at UCLA and the Los Angeles Zoo, doctors and veterinarians will learn from each other by sharing similar cases, visi...
Source: UCLA Newsroom: Health Sciences - September 19, 2012 Category: Universities & Medical Training Source Type: news

FDA Warns Against Use of Diarrhea Drug from El Salvador
Ingredient in Intestinomicina linked to serious health problems, including bone marrow toxicity Source: HealthDay Related MedlinePlus Pages: Diarrhea, Drug Safety
Source: MedlinePlus Health News - September 19, 2012 Category: Consumer Health News Source Type: news

Prenatal PFC Exposure Linked To Lower Birth Weight In Girls
ATLANTA - The National Institute of Environmental Health Sciences published research Aug. 30 in which the researchers conclude that higher prenatal exposure to perfluorochemicals is correlated with lower birth weight in girl infants; researchers also report that higher body mass indexes at 20 months are correlated with higher prenatal exposure to the chemicals.
Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - September 19, 2012 Category: Medical Law Source Type: news

DuPont Removes Lawsuit Alleging Kidney Cancer Link To Fugitive Perfluorooctanoate
COLUMBUS, Ohio - DuPont filed notice of removal Sept. 6 in the U.S. District Court for the Southern District of Ohio in a personal injury lawsuit alleging that ammonium perfluorooctanoate exposure caused the plaintiff to contract renal cancer and required the removal of a kidney (Thomas Yakubik v. E.I. DuPont de Nemours & Co., No. 12-815, S.D. Ohio).
Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - September 19, 2012 Category: Medical Law Source Type: news

Flea Treatment Plaintiffs Oppose Ruling On Certification Before Discovery Permitted
NEWARK, N.J. - The plaintiffs in topical flea and tick treatment products liability class actions coordinated in the U.S. District Court for the District of New Jersey press their argument in a reply brief filed Sept. 7 for discovery before the court considers defense motions to strike class claims and to deny class certification (Aundria Arlandson, et al. v. Hartz Mountain Corp., et al., No. 10-1050 $(coordinated$), D. N.J.; See 8/21/12, Page 30).
Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - September 19, 2012 Category: Medical Law Source Type: news

Property Owners, TVA Offer Plans For Damages Trial In Coal Slurry Spill Litigation
KNOXVILLE, Tenn. - The Tennessee Valley Authority and the plaintiffs seeking to recover for the failure in December 2008 of a coal ash slurry impoundment levy near Kingston, Tenn., filed proposals Sept. 13 for the conduct of the damages phase of the litigation consolidated in the U.S. District Court for the Eastern District of Tennessee; the authority was found liable for the spill in an order issued Aug. 23 based on the record from the September 2011 Phase I trial (In re: Tennessee Valley Authority Ash Spill Cases $(George Chesney$), 09-09 $(consolidated$), E.D. Tenn.; See 9/4/12, Page 4).
Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - September 19, 2012 Category: Medical Law Source Type: news

No Coverage For Successor Company Under Applicable Illinois Law, N.Y. Panel Says
NEW YORK - No coverage is owed to the successor company of an insured for underlying suits alleging injuries caused by exposure to popcorn butter flavoring products because the trial court incorrectly applied New York law rather than Illinois law, which follows a limited de facto merger exception, the First Department New York Supreme Court Appellate Division said Sept. 11 (International Flavors & Fragrances Inc., et al., v St. Paul Protective Insurance Co., No. 601723/08, N.Y. Sup., App. Div., 1st Dept.; 2012 N.Y. App. Div. LEXIS 6050).
Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - September 19, 2012 Category: Medical Law Source Type: news

9th Circuit Panel Denies For Lack Of Jurisdiction Appeal By Excluded Expert
SAN FRANCISCO - A unanimous Ninth Circuit U.S. Court of Appeals panel entered an opinion Sept. 5 denying for lack of jurisdiction an expert's appeal of an order excluding him from a diacetyl exposure personal injury case; the panel also concluded that the expert lacks standing to appeal (Larry I. Newkirk, et uxor v. ConAgra Foods Inc., et al., No. 10-35667 $(consolidated$), 9th Cir.; See 6/21/11, Page 5).
Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - September 19, 2012 Category: Medical Law Source Type: news

No-Evidence Judgment Granted To Refrigeration Contractor In Freon Exposure Lawsuit
ALEXANDRIA, Va. - No-evidence judgment was granted Sept. 11 to a refrigeration contractor in a Freon-exposure personal injury lawsuit in the U.S. District Court for the Eastern District Virginia; opinions by the causation experts designated by the plaintiffs were ruled unreliable and inadmissible (Deborah Zellars v. NexTech Northeast, No. 11-967 $(consolidated$), E.D. Va.; 2012 U.S. Dist. LEXIS 129527).
Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - September 19, 2012 Category: Medical Law Source Type: news