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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 39.

European guidelines for diagnosis and treatment of adenovirus infection in leukemia and stem cell transplantation: summary of ECIL‐4 (2011)
Abstract Human adenovirus (HAdV) infections are increasingly recognized as important pathogens in immunocompromised hosts, especially in patients with severely suppressed T‐cell function. The 4th European Conference of Infections in Leukemia (ECIL‐4) has developed evidence‐based guidelines for diagnosis and management of HAdV infections. The risk for HAdV‐associated disease is increased in children, and risk factors for HAdV disease are T‐cell depletion, unrelated and cord blood hematopoietic stem cell transplantation, graft‐versus‐host disease grades III–IV, and lymphopenia. The recommended technique for m...
Source: Transplant Infectious Disease - October 1, 2012 Category: Transplant Surgery Authors: S. Matthes‐Martin, T. Feuchtinger, P.J. Shaw, D. Engelhard, H.H. Hirsch, C. Cordonnier, P. Ljungman, Tags: Review article Source Type: research

Keeping kidneys.
Authors: Abstract Most countries struggle to meet the demand for transplant kidneys, but a few are reaping the benefits of systems dedicated to increasing the number of organ donations after death. Ben Jones and Mireia Bes report. PMID: 23109738 [PubMed - in process]
Source: Bulletin of the World Health Organization - October 1, 2012 Category: Global & Universal Tags: Bull World Health Organ Source Type: research

Should peritoneal dialysis catheters be removed at the time of kidney transplantation?
CONCLUSIONS: : PD catheter removal should be considered at the time of renal transplantation, as postoperative PD-related failure/complication rates are high. PMID: 23093631 [PubMed]
Source: Canadian Urological Association Journal - October 1, 2012 Category: Urology & Nephrology Authors: Warren J, Jones E, Sener A, Drage M, Taqi A, Griffin S, Watson C, Luke PP Tags: Can Urol Assoc J Source Type: research

Phaeohyphomycosis caused by Pyrenochaeta romeroi mimicking a plantar wart in a kidney transplant recipient
Source: Transplant Infectious Disease - October 1, 2012 Category: Transplant Surgery Authors: M.A. Ocampo, J. Kanitakis, A.‐L. Bienvenu, C. Chauvet, S. Euvrard Tags: Letter to the Editor Source Type: research

Selective Cerebro‐Myocardial Perfusion Under Mild Hypothermia During Primary Repair for Aortic Coarctation With Ventricular Septal Defect
Abstract Controversy still exists on the use of deep hypothermic circulatory arrest (DHCA) and selective antegrade cerebral perfusion (SACP) on postoperative recovery. Selective cerebro‐myocardial perfusion (SCMP) has been described in neonatal and infant arch surgery. We therefore report outcomes of patients undergoing SCMP under mild hypothermia compared with DHCA and SACP. One hundred ten consecutive patients undergoing anatomic reconstruction of coarctation of the aorta (CoA) with ventricular septal defect (VSD) closure between January 1999 and July 2011 were retrospectively reviewed. Patients repaired under continuo...
Source: Artificial Organs - October 1, 2012 Category: Transplant Surgery Authors: Huiwen Chen, Haifa Hong, Zhongqun Zhu, Jinfen Liu Source Type: research

Case Report of Extended “Temporary” Use of Levitronix CentriMag Right Ventricular Assist Device
Source: Artificial Organs - October 1, 2012 Category: Transplant Surgery Authors: Philipp Ortmann, Diyar Saeed, Artur Lichtenberg Tags: Letter to the Editor Source Type: research

Medical Outcomes in African American Live Kidney Donors: A Matched Cohort Study
It is uncertain if live kidney donation increases future risk of hypertension and kidney disease in African Americans. We conducted a cohort study across two transplant centers enrolling African Americans who donated between 1993 and 2006. A comparison group of African American nondonors were selected from healthy participants in the Coronary Artery Risk Development in Young Adults (CARDIA) prospective cohort study. A total of 103 donors and 235 matched nondonors were assessed at mean ( ± SD) of 6.8 ± 2.3 and 6.4 ± 2.2 years after donation or cohort entry, respectively. The primary outcome was risk of hypertension in do...
Source: American Journal of Transplantation - October 1, 2012 Category: Transplant Surgery Authors: M. D. Doshi, M. O. Goggins, L. Li, A. X. Garg Tags: Original Article Source Type: research

Endovascular caudal retraction of the cranial end of a misplaced Viatorr TIPS prior to liver transplantation.
We describe the first known manipulation of a covered stent graft prior to transplantation. The stent graft, which extended well into the IVC, was snared from a femoral approach and deflected caudally in order to document feasibility and nonadherence to the vein wall prior to definitive surgical planning of liver transplantation. Provisions were made for endovascular retraction during actual transplant surgery 9 weeks later, but this became unnecessary when manual retraction of the exposed liver enabled suprahepatic IVC clamping. Due to the nonadherent nature of the outer graft material, compared with a bare metal stent, e...
Source: Baylor University Medical Center Proceedings - October 1, 2012 Category: Universities & Medical Training Authors: Ray MJ, Savage C, Klintmalm GB, Rees CR Tags: Proc (Bayl Univ Med Cent) Source Type: research

Center competition and outcome following liver transplantation
The objective was to determine whether competition within a DSA is associated with post‐transplant outcomes and variations in patients waitlisted within a DSA. United Network for Organ Sharing (UNOS) data (38,385 adult cadaveric liver transplant recipients transplanted between 1/1/2003 and 12/31/2009) were analyzed to assess differences in liver recipients and donors and post‐transplant survival by competition among centers. Main outcome measures studied were patient characteristics, actual and risk‐adjusted graft and patient survival‐rates after transplantation, organ quality as quantified by donor risk index (DRI...
Source: Liver Transplantation - October 1, 2012 Category: Transplant Surgery Authors: Jeffrey B. Halldorson, Harry J. Paarsch, Jennifer L. Dodge, Alberto M. Segre, Jennifer Lai, John P. Roberts Tags: Original Article Source Type: research

Cholestatic hepatitis C following liver transplantation: An outcome‐based histological definition, clinical predictors and prognosis
Conclusions: We propose diagnostic criteria for cholestatic HCV, which include specific criteria (the presence of ò 3 of 4 histopathologic lesions on biopsy) and other supportive and exclusionary criteria. Older donor age and rejection increase the risk of cholestatic HCV, and elevation in TB may help identify these patients. © 2012 American Association for the Study of Liver Diseases
Source: Liver Transplantation - October 1, 2012 Category: Transplant Surgery Authors: Elizabeth C. Verna, Rita Abdelmessih, Marcela A. Salomao, Jay Lefkowitch, Roger K. Moreira, Robert S. Brown Tags: Original Articles Source Type: research

Subacute cytomegalovirus appendicitis in a renal transplant recipient
We describe the first case, to our knowledge, documenting CMV appendicitis in a renal transplant patient, and its clinical presentation, diagnosis, and treatment.
Source: Transplant Infectious Disease - October 1, 2012 Category: Transplant Surgery Authors: A. Posen, I. Renckens, X. Sagaert, D. Kuypers Tags: Images in transplant infectious disease Source Type: research

Association of vitamin D receptor FokI and ApaI polymorphisms with human cytomegalovirus disease in the first three months following kidney transplantation.
CONCLUSIONS: The recessive f allelic gene of VDR can be regarded as a risk factor of CMVD while FF recipients have lower incidence of CMVD after kidney transplantation. ApaI genotypes showed no relationship with predisposition to CMVD. PMID: 23044313 [PubMed - in process]
Source: Chinese Medical Journal - October 1, 2012 Category: Journals (General) Authors: Zhao YG, Shi BY, Xiao L, Qian YY, Feng K, He XY, Xu XG Tags: Chin Med J (Engl) Source Type: research

Clinical application of real time-polymerase chain reaction in determining cytomegalovirus viral DNA load in renal transplant recipients.
CONCLUSION: CMV infection is a risk factor of acute renal transplant rejection and CMV infection should be prevented and treated in renal transplant recipients. PMID: 23044327 [PubMed - in process]
Source: Chinese Medical Journal - October 1, 2012 Category: Journals (General) Authors: Zhang CB, Lai HY, Xu HT, Wang DG, Xiao F Tags: Chin Med J (Engl) Source Type: research

A Surveillance Model for Skin Cancer in Organ Transplant Recipients: A 22‐Year Prospective Study in an Ethnically Diverse Population
This study determines overall burden of cancer and relevant intervals for strategic surveillance in an ethnically diverse transplant population. Prospective data on time to first and subsequent cancers and cumulative burden with respect to defined risk factors were analyzed in a cohort of 1010 patients in a UK center over 22 years. Among 931 individuals transplanted >6 months (mean 10.3 years), 1820 skin cancers occurred in 267 (29%) individuals and were multiple in 66%. Cumulative incidence at 5, 10, 20 and 30 years was 11%, 25%, 54% and 74%, with median time to second, third and fourth cancers of 24, 14.7 and 8.4 mont...
Source: American Journal of Transplantation - October 1, 2012 Category: Transplant Surgery Authors: C. A. Harwood, D. Mesher, J. M. McGregor, L. Mitchell, M. L.‐Green, M. Raftery, R. Cerio, I. M. Leigh, P. Sasieni, C. M. Proby Source Type: research

The Protective Effect of St. Thomas Cardioplegia Enriched With Zacopride on the Isolated Rat Heart
Abstract The activation of the heart inward rectifier potassium channel (IK1) can reduce the injury of myocardial cells by shortening the action potential duration and reducing intracellular calcium overload. Zacopride is a selective IK1 agonist and suppresses triggered arrhythmias in rat hearts. This investigation studied the effects of St. Thomas (ST) cardioplegia enriched with Zacopride on the isolated rat heart model. Sprague‐Dawley rat hearts were harvested and perfused for 20 minutes with 37°C Krebs‐Henseleit (KH) buffer followed by 15 minute perfusion with 4°C calcium‐free KH buffer in the Control group (Con...
Source: Artificial Organs - October 1, 2012 Category: Transplant Surgery Authors: Bei Wu, Cun Long, Feilong Hei, Shilei Wang Source Type: research

Incidence of Primary and Second Cancers in Renal Transplant Recipients: A Multicenter Cohort Study
Limited data exist about cancer prognosis and the development of second cancers in renal transplant recipients. In a retrospective cohort study on 3537 patients incidence rates of the first and, if any, of a second cancer, and standardized incidence ratios [SIR (95% CI)] were computed. Two hundred and sixty‐three (7.5%) patients developed a NMSC, and 253 (7.2%) another type of cancer after a median follow‐up of 6.5 and 9.0 years, respectively. A statistically significant excess risk, if compared to an age‐ and sex‐matched reference general population, was observed for Kaposi sarcoma and NMSC, followed by non‐Hodg...
Source: American Journal of Transplantation - October 1, 2012 Category: Transplant Surgery Authors: G. Tessari, L. Naldi, L. Boschiero, E. Minetti, S. Sandrini, F. Nacchia, F. Valerio, C. Rugiu, F. Sassi, E. Gotti, L. Fonte, G. Talamini, G. Girolomoni Tags: Brief Communication Source Type: research

Approach to kidney transplant in sensitized potential transplant recipients.
Abstract More than one-third of patients on waiting lists for kidney transplant are sensitized. Most have previously formed donor-specific and non-donor-specific serum antibodies and/or positive crossmatch by complement-dependent cytotoxity and/or flow cytometry. Two categories of alloantibodies include antibodies against major histocompatibility complex human leukocyte antigen class 1 and class 2 and antibodies against minor histocompatibility complex. A current positive crossmatch is an absolute contraindication for transplant. Positive historical panel reactive antibody and/or donor-specific antibodies (human le...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 1, 2012 Category: Transplant Surgery Authors: Barbari A, Abbas S, Jaafar M Tags: Exp Clin Transplant Source Type: research

Long-term graft function in a randomized clinical trial comparing laparoscopic versus open donor nephrectomy.
CONCLUSIONS: Although earlier experiences with laparoscopic donor nephrectomies were associated with concerns about long-term effects of laparoscopic donation on the graft function in the recipient, our long-term results confirm that laparoscopic donor nephrectomy provides similar graft outcome to open donor nephrectomy. PMID: 23031082 [PubMed - in process]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 1, 2012 Category: Transplant Surgery Authors: Simforoosh N, Basiri A, Shakhssalim N, Gooran S, Tabibi A, Khoshdel A, Ziaee SA Tags: Exp Clin Transplant Source Type: research

Risk factors for steroid-resistant T-cell-mediated acute cellular rejection and their effect on kidney graft and patient outcome.
CONCLUSIONS: Prebiopsy low cyclosporine trough levels and associated chronic changes among patients who were maintained on calcineurin inhibitor-based regimens represented the most-important risk factors for the early steroid-resistant group. Rescue therapies improve short-term graft outcome; however, they did not affect either patient or long-term graft survival after 5 years' follow-up. PMID: 23031083 [PubMed - in process]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 1, 2012 Category: Transplant Surgery Authors: Awadain W, Gheith O, Hassan A, Hassan N, El-Deeb S, El-Agroudy A, Fouda A, Ghoneim MA Tags: Exp Clin Transplant Source Type: research

Resistive index of the remaining kidney in allograft kidney donors.
CONCLUSIONS: Although a statistically significant increase in resistive index values of the remaining kidney was seen 90 days after the nephrectomy, these values have remained within the normal limits of renal resistive index. So, our findings indicate that resistive index measurement is useful in assessing the diseased condition of the remaining kidney after removing the contralateral kidney. PMID: 23031084 [PubMed - in process]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 1, 2012 Category: Transplant Surgery Authors: Nekouei S, Ahmadnia H, Abedi M, Alamolhodaee MH, Abedi MS Tags: Exp Clin Transplant Source Type: research

Sex matching plays a role in outcome of kidney transplant.
CONCLUSIONS: These results revealed that sex mismatching (group 2, male donor to female recipient) had the best 1-year graft function but the same 1-year patient and graft survival. PMID: 23031085 [PubMed - in process]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 1, 2012 Category: Transplant Surgery Authors: Abou-Jaoude MM, Abou-Jaoude WJ, Almawi WY Tags: Exp Clin Transplant Source Type: research

Treatment of refractory cerebral aspergillosis in a liver transplant recipient with voriconazole: case report and review of the literature.
CONCLUSIONS: Voriconazole was effective and safe in the treatment of cerebral aspergillosis in this liver transplant recipient. PMID: 23031086 [PubMed - in process]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 1, 2012 Category: Transplant Surgery Authors: Cherian T, Giakoustidis A, Yokoyama S, Heneghan M, O'Grady J, Rela M, Wendon J, Heaton DN, Verma A Tags: Exp Clin Transplant Source Type: research

Endoscopic Vision‐Based Tracking of Multiple Surgical Instruments During Robot‐Assisted Surgery
Abstract Robot‐assisted minimally invasive surgery is effective for operations in limited space. Enhancing safety based on automatic tracking of surgical instrument position to prevent inadvertent harmful events such as tissue perforation or instrument collisions could be a meaningful augmentation to current robotic surgical systems. A vision‐based instrument tracking scheme as a core algorithm to implement such functions was developed in this study. An automatic tracking scheme is proposed as a chain of computer vision techniques, including classification of metallic properties using k‐means clustering and instrumen...
Source: Artificial Organs - October 1, 2012 Category: Transplant Surgery Authors: Jiwon Ryu, Jaesoon Choi, Hee Chan Kim Source Type: research

MCQs
Regarding the ventricular assist devices (VAD) which of the following are true? Primary graft dysfunction in heart transplant recipients is an indication
Source: Anaesthesia and intensive care medicine - October 1, 2012 Category: Anesthesiology Authors: Henry G.W. Paw, Vijayanand Nadella Tags: Test yourself Source Type: research

Cardiopulmonary transplantation
Abstract: More than 7000 cardiopulmonary transplants were carried out worldwide in 2009 across the 388 centres reporting to the International Registry. The 100,000th heart transplant mark has been passed. Heart transplantation is a proven surgical option for selected patients who have advanced heart failure refractory to surgical or medical management. Lung transplantation is the definitive treatment for end-stage lung disease for patients who have failed medical therapy. More than 90% of adult patients presenting for heart transplantation have dilated cardiomyopathy or ischaemic cardiomyopathy. Anaesthetic principles for ...
Source: Anaesthesia and intensive care medicine - October 1, 2012 Category: Anesthesiology Authors: Barbora Parizkova, I. Gavin Wright Tags: Cardiac anaesthesia Source Type: research

Outcome of Clostridium difficile‐associated disease in solid organ transplant recipients: a prospective and multicentre cohort study
Abstract Clostridium difficile‐associated disease (CDAD) is the most common cause of nosocomial diarrhea. Information about CDAD in solid organ transplant (SOT) recipients is scarce. To determine its epidemiology and risk factors, we conducted a cohort study in which 4472 SOT patients were prospectively included in the RESITRA/REIPI (Spanish Research Network for the Study of Infection in Transplantation) database between July 2003 and July 2006. Forty‐two episodes of CDAD were diagnosed in 36 patients. The overall incidence was 0.94%. Median onset of infection was 31.5 days (range 6–741); in half the cases, onset o...
Source: Transplant International - October 1, 2012 Category: Transplant Surgery Authors: Oscar Len, Dolores Rodríguez‐Pardo, Joan Gavaldà, José María Aguado, Marino Blanes, Nuria Borrell, Germán Bou, Jordi Carratalà, José Miguel Cisneros, Jesús Fortún, Mercé Gurguí, Miguel Montejo, Carlos Cervera, Patricia Muñoz, Angel Asensio, Tags: ORIGINAL ARTICLE Source Type: research

Left Ventricular Assist Device Support and Myocardial Recovery in Recent Onset Cardiomyopathy
Conclusion: In a multicenter registry of ROCM, BTR was common and occurred in the majority of subjects requiring LVAD support. Histology and LVEDD may assist in predicting potential for BTR in ROCM.
Source: Journal of Cardiac Failure - October 1, 2012 Category: Cardiology Authors: John P. Boehmer, Randall C. Starling, Leslie T. Cooper, Guillermo Torre-Amione, Ilan Wittstein, G. William Dec, David W. Markham, Mark J. Zucker, John Gorcsan, Charles McTiernan, Kevin Kip, Dennis M. McNamara, IMAC Investigators Tags: Clinical Investigations Source Type: research

Microlymphatic Surgery for the Treatment of Iatrogenic Lymphedema
Lymphedema is a chronic and progressive condition that occurs after cancer treatment. Autologous lymph node transplant, or microsurgical vascularized lymph node transfer (ALNT), is a surgical treatment option that brings vascularized vascular endothelial growth factor-C–producing tissue into the operated field to promote lymphangiogenesis and bridge the distal obstructed lymphatic system with the proximal lymphatic system. Operative techniques for upper- and lower-extremity ALNT are described with 3 donor lymph node flaps (inguinal, thoracic, cervical). Surgical technique is described for the combination of ALNT with abd...
Source: Clinics in Plastic Surgery - October 1, 2012 Category: Cosmetic Surgery Authors: Corinne Becker, Julie V. Vasile, Joshua L. Levine, Bernardo N. Batista, Rebecca M. Studinger, Constance M. Chen, Marc Riquet Source Type: research

Extensive emphysematous pyelonephritis in a renal allograft treated conservatively: case report and review of the literature
We present a case of severe EPN caused by Klebsiella pneumoniae, successfully managed with early PCD, and propose a step‐up strategy aimed toward graft preservation.
Source: Transplant Infectious Disease - October 1, 2012 Category: Transplant Surgery Authors: S. Alexander, S. Varughese, V.G. David, S.V. Kodgire, R.P. Mukha, N.S. Kekre, V. Tamilarasi, C.K. Jacob, G.T. John Tags: Case report Source Type: research

Clinical significance of quantitative cytomegalovirus detection in bronchoalveolar lavage fluid in lung transplant recipients
ConclusionsDetection of CMV‐positive BAL after the sixth month appears common, but did not correlate with BOS‐free survival after LTx in this study. An increased risk of developing blood antigenemia was observed in patients with positive CMV PCR in BAL, warranting close follow‐up.
Source: Transplant Infectious Disease - October 1, 2012 Category: Transplant Surgery Authors: E. Schlischewsky, T. Fuehner, G. Warnecke, T. Welte, A. Haverich, T. Ganzenmueller, A. Heim, J. Gottlieb Tags: Original Article Source Type: research

Impact of Single-Ventricle Physiology on Death After Heart Transplantation in Adults With Congenital Heart Disease [ORIGINAL ARTICLES: PEDIATRIC CARDIAC]
Conclusions Overall case-mix of ACHD recipients (1V vs 2V) has not changed over time. Initial 1V anatomy increases post-HTx death among ACHD recipients, whereas 2V patients have mortality rates similar to non-CHD recipients. National and international transplant registries should include specific CHD diagnoses because this factor plays such a large role in determining early outcomes.
Source: The Annals of Thoracic Surgery - October 1, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Karamlou, T., Diggs, B. S., Welke, K., Tibayan, F., Gelow, J., Guyton, S. W., Slater, M. S., Broberg, C., Song, H. K. Tags: Congenital - cyanotic, Transplantation - heart ORIGINAL ARTICLES: PEDIATRIC CARDIAC Source Type: research

Author Index
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Source Type: research

Pain Syndrome Induced by Calcineurin Inhibitor and Resolved by Conversion to Sirolimus in a Child After Kidney Transplantation: A Case Report
Abstract: Pain induced by calcineurin inhibitors is a rare complication of unknown pathogenesis. We have reported herein a 7-year-old child who presented with abdominal pain, vomiting, and weight loss showing no significant findings after an extensive laboratory and imaging workup. After conversion from tacrolimus to sirolimus, there was complete resolution of the gastrointestinal symptoms and pain; the patient displays excellent renal function. Calcineurin inhibitor-induced pain syndrome is diagnosis of exclusion but must be considered because the withdrawal of this immunosuppressive agent is associated with improvement ...
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: L.C. Prates, S.Z.P. Rigatto, A.C.B. Lutaif, L.C. Oliveira, L.M. Pereira, L.C. Passerotti, V.M.S. Belangero Tags: Case Reports Source Type: research

Uncommon Cause of Chest Pain in a Renal Transplantation Patient With Autosomal Dominant Polycystic Kidney Disease: A Case Report
We report the case of a 62-year-old male who underwent a kidney transplantation from a cadaveric donor in 1997 (etiology of the ESRD was ADPKD), and was admitted to the emergency department with complaints of chest pain radiating to both shoulders and the interscapular region. An echocardiogram was showed compression of the right atrium by a large liver cyst without associated ventricular dysfunction. Computer tomography–guided drainage of the cyst was performed and an Enterobacter aerogenes sensitive to carbamapenemes was isolated from respective cultures. The patient presented a favorable clinical outcome with prolonge...
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: L. Rodrigues, M. Neves, S. Machado, H. Sá, F. Macário, R. Alves, A. Mota, M. Campos Tags: Case Reports Source Type: research

Use of Enteroscopy for Treating Pancreatitis in a Pancreas and Kidney Transplantation Patient With Roux-en-Y Portoenteric Derivation—A Case Report
We present a case of the use of single-balloon enteroscopy in the treatment of cronic pancreatitis in the donor pancreas.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: A. Costa, W. Takahashi, T. Genzini, E.T. Yamashita, F.E. Pessanha, L.E. Ianhez, R.A. Oliveira, M. Perosa Tags: Case Reports Source Type: research

Single-Balloon Enteroscopy for Treating Roux-en-y Choledochojejunostomy Stenosis After Liver Transplantation: A Case Report
We report a case of single-balloon enteroscopy plus endoscopic retrograde cholangiopancreatography for the treatment of a pinpoint stricture in a hepaticojejunal anastomosis after liver transplantation.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: A. Costa-Genzini, W. Takahashi, R.G. dos Santos, M.T.C.O. Gaboardi, H.M. Noujaim, E.T. Yamashita, M. Perosa, T. Genzini Tags: Case Reports Source Type: research

Case Report of Hepatic Mucormycosis After Liver Transplantation: Successful Treatment With Liposomal Amphotericin B Followed by Posaconazole Sequential Therapy
We describe here an unusual case of hepatic mucormycosis in a liver transplant recipient that was successfully treated with clinical therapy based on liposomal amphotericin B followed by posaconazole, without surgical resection.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: C.S. Abboud, M.D. Bergamasco, C.E.S. Baía, M.P. Lallée, A.S.C. Zan, M.M. Zamorano, O.I. Pereira, S. Mies Tags: Case Reports Source Type: research

Stress-Induced Cardiomyopathy (Takotsubo Cardiomyopathy) After Liver Transplantation—Report of Two Cases
In conclusion, stress-induced cardiomyopathy, an underestimated cause of heart complications, should be considered as a possible cause of cardiac failure in liver transplant patients.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: L.J. Tachotti Pires, M.N. Cardoso Curiati, F. Vissoci Reiche, O.M. Silvestre, S. Mangini, R. Carballo Afonso, B.-H. Ferraz-Neto, F. Bacal Tags: Case Reports Source Type: research

Expression of Pancreatic Endocrine Markers by Mesenchymal Stem Cells From Human Adipose Tissue
Abstract: Mesenchymal stem cells (MSCs) from human adipose tissue have a great potential for use in cell therapy due to their ease of isolation, expansion, and differentiation, besides the relative acceptance from the ethical point of view. Our intention was to isolate and promote in vitro expansion and differentiation of MSCs from human adipose tissue into cells with a pancreatic endocrine phenotype. Human adipose tissue obtained from patients undergoing abdominal dermolipectomy was digested with type I collagenase. MSCs isolated by plastic adherence and characterized by cytochemistry and FACS were expanded in vitro. MSC...
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: A.C. Silva, L.S. Percegona, A.L. França, T.M. dos Santos, C.C. Perini, P. González, C.L.K. Rebelatto, N.O.S. Câmara, C.A.M. Aita Tags: Experimental Studies Source Type: research

Protective Effects of Human Amniotic Fluid Stem Cells in a Model of Aorta Allograft Vasculopathy in Rats
Conclusions: These preliminary results showed that hAFSC suppressed inflammation and myofibroblast migration to the intima, which may contribute to ameliorate vascular changes in CAV.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: A.C. Santana, H. Dellê, R.C. Cavaglieri, M.A.B. Lopes, R.P.V. Francisco, M. Zugaib, S.P. Bydlowski, I.L. Noronha Tags: Experimental Studies Source Type: research

Effects of Prednisone on Mucociliary Clearance in a Murine Model
The objective of this study was to evaluate the effects of prednisone on mucociliary clearance. A total of 120 male Wistar rats were distributed into 4 groups. Animals in P1, P2, and P3 groups received daily doses of prednisone (0.625, 1.25, and 2.5 mg/kg/d), and hosts in the Sal group underwent gavage with saline solution (2.5 mL/d). After 7, 15, and 30 days, treatment, animals were killed. We assessed ciliary beating frequency (CBF), mucociliary transport velocity (MCTV), and mucus transportability (MT). There was no significant difference for CBF regarding dose (P = .089) or treatment duration (P = .175). MCTV values of...
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: K.A. Oliveira-Braga, N.A. Nepomuceno, A.T. Correia, F.B. Jatene, P.M. Pêgo-Fernandes Tags: Experimental Studies Source Type: research

The Impact of Tacrolimus as Rescue Therapy in Children Using a Double Immunosuppressive Regimen After Heart Transplantation
Conclusion: Tacrolimus is effective as rescue therapy for refractory rejection and is a therapeutic option for pediatric patients.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: K.C. Branco, E. Azeka, E. Trindade, F.R.B. Galas, L.A. Hajjar, L. Benvenuti, A. Riso, C. Tanamati, J. Penha, J.O.C. Auler, M. Jatene Tags: Thoracic Transplantation Source Type: research

Tricuspid Valve Injury After Heart Transplantation Due to Endomyocardial Biopsy: An Analysis of 3550 Biopsies
Conclusions: Histological evidence of chordal tissue in EMB specimens is a real-world problem of relatively low frequency. Traumatic tricuspid valve injury due to EMB rarely leads to severe valvular regurgitation; only a minority of patients develop significant clinical symptoms. Hemodynamic and echocardiographic alterations are also less often observed in most patients.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: A.I. Fiorelli, G.H.B. Coelho, V.D. Aiello, L.A. Benvenuti, J.F. Palazzo, V.P. Santos Júnior, B. Canizares, R.R. Dias, N.A.G. Stolf Tags: Thoracic Transplantation Source Type: research

Comparative Analysis of the Complications of 5347 Endomyocardial Biopsies Applied to Patients After Heart Transplantation and With Cardiomyopathies: A Single-center Study
Conclusions: EMB can be accomplished with a low risk of complications and high effectiveness to diagnose CMP and rejection after HT. However, the risk is great among patients with CMP due to their anatomic characteristics. Children also constitute a risk group for EMB due to their small size in addition to the heart disease. The risk of injury to the tricuspid valve was higher among the HT group.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: A.I. Fiorelli, L. Benvenuti, V. Aielo, A.Q. Coelho, J.F. Palazzo, R. Rossener, A.C.P. Barreto, C. Mady, F. Bacal, E. Bocchi, N.A.G. Stolf Tags: Thoracic Transplantation Source Type: research

Risk Factor Analysis of Late Survival After Heart Transplantation According to Donor Profile: A Multi-Institutional Retrospective Study of 512 Transplants
Conclusions: Donor age older than 40 years represents an important risk factor for survival after HTx. Neither donor gender nor norepinephrine use negatively affected early survival.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: A.I. Fiorelli, J.N. Branco, J.J. Dinkhuysen, J.L. Oliveira Junior, T.V. Pereira, L.F.L. Dinardi, M.M. Santos, R.R. Dias, L.A. Pereira, N.A.G. Stolf Tags: Thoracic Transplantation Source Type: research

Risk Factors and Survival Impact of Primary Graft Dysfunction After Lung Transplantation in a Single Institution
Conclusion: PGD showed an important impacts on operative and 90-day mortality rates, mechanical ventilation time, and overall survival among lung transplant patients. PGD at 72 hours was a better predictor of lung transplant outcomes than at 48 hours. The use of donors with a smoking history or of advanced age were risk factors for the development of PGD.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: M.N. Samano, L.M. Fernandes, J.C.B. Baranauskas, A.T. Correia, J.E. Afonso, R.H.O.B. Teixeira, M.L. Caramori, P.M. Pêgo-Fernandes, F.B. Jatene Tags: Thoracic Transplantation Source Type: research

Hepatocellular Carcinoma Recurrence Among Liver Transplant Recipients Within the Milan Criteria
Conclusions: Despite strict candidate selection criteria, HCC recurrence may occur after OLT, bearing a significant impact on posttransplant outcomes to optimize results requires refinements in candidate selection, as well as well-defined cost-effective post-OLT surveillance protocols.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: G. Felga, A.S. Evangelista, P.R. Salvalaggio, L.A. Curvelo, B. Della Guardia, M.D. Almeida, R.C. Afonso, B.H. Ferraz-Neto Tags: Liver, Intestinal, and Multivisceral Transplantation Source Type: research

Co-infection and Clinical Impact of Human Herpesvirus 5 and 6 in Liver Transplantation
Conclusions: HHV-5/6–infected patients displayed more allograft rejection episodes, coinfections, and concomitant bacterial infections, besides an higher risk for CMV disease.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: A.M. Sampaio, A.C. Guardia, A. Milan, A.N. Sasaki, P.D. Andrade, S.H.A. Bonon, R.S.B. Stucchi, S.C. Botelho Costa, I.F.S.F. Boin Tags: Liver, Intestinal, and Multivisceral Transplantation Source Type: research

Can Pre–Liver Transplantation Renal Insufficiency Using a Creatinine Clearance Calculator Predict Long-Term Survival?
The objective of this study was to study renal insufficiency observed pretransplantation and its long-term impact after liver transplantation. Methods: We analyzed retrospectively an electronic database collected prospectively including transplant records from June 1994 to October 2010 using piggyback venous reconstruction. The exclusion criteria were chronic kidney disease, acute hepatic failure, children up to 12 years of age, and retransplantations. Renal insufficiency was defined by the creatinine clearance (CCr) calculated using the Cockcroft-Gault method. Patients were distributed into 3 groups: CCr >90, between 90...
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: I.F.S.F. Boin, E.C. de Ataide, E.P.O. Dias, R.S.B. Stucchi, T. Seva-Pereira, G. Calomeni, C.C. Capel Junior, M. Mazzali Tags: Liver, Intestinal, and Multivisceral Transplantation Source Type: research

Early Allograft Dysfunction and Liver Transplant Outcomes: A Single Center Retrospective Study
Conclusion: Patients with EAD show a significantly higher risk for allograft loss, but with a comparable survival after transplantation. Despite their worse outcomes, it seems that not all of these recipients behave equally.
Source: Transplantation Proceedings - October 1, 2012 Category: Transplant Surgery Authors: P.R. Salvalaggio, G.E. Felga, R.C. Afonso, B.H. Ferraz-Neto Tags: Liver, Intestinal, and Multivisceral Transplantation Source Type: research